CN216457425U

CN216457425U - Three laminar sample liquid autosegregation devices

Info

Publication number: CN216457425U
Application number: CN202123000492.9U
Authority: CN
Inventors: 张海燕; 詹晓春; 詹斯喻; 付凤霞
Original assignee: Zhengzhou Zhongpu Medical Equipment Co ltd
Current assignee: Zhengzhou Zhongpu Medical Equipment Co ltd
Priority date: 2021-11-29
Filing date: 2021-11-29
Publication date: 2022-05-10
Anticipated expiration: 2031-11-29

Abstract

The utility model relates to a three-layer type automatic sample liquid separation device which comprises a lower barrel and an upper barrel, wherein the upper barrel and the lower barrel are vertically inserted and matched, a filtering membrane is arranged in the lower barrel, an inserting sleeve part for inserting a cover-opening-free sample bottle is arranged at the upper part of the upper barrel, a poking-breaking structure is arranged in the upper barrel and used for poking and breaking the end part of the cover-opening-free sample bottle in the cover-opening-free sample bottle inserting sleeve process, and the tip part of the poking-breaking structure deviates from the center of the upper barrel. Exempt from to uncap sample bottle is the direct relation of inserting the joining in marriage, and the non-screw thread spiral-assembling, convenient operation, and the sharp portion of disclosing broken structure is skew go up the center of barrel, more do benefit to disclose broken disposable closing cap and make sample liquid flow out.

Description

Three laminar sample liquid autosegregation devices

Technical Field

The utility model relates to the field of sample separation instruments, in particular to a three-layer type automatic sample liquid separation device.

Background

A filter (i.e., a separating device) is required to separate the cells from the cell retaining fluid and adhere the cells to the slide during the process of completing the exfoliated cell smear using the liquid-based cell automatic slide-making apparatus.

The utility model discloses a filter suitable for among automatic film-making equipment of liquid base cell as utility model patent of grant publication No. CN209727578U, it includes filter epitheca, filter screen, filtration membrane, filter inferior valve. The filter upper shell is internally provided with a liquid storage cavity for storing specimen base liquid. The filter screen sets up the intermediate position in filtering the shell for filter the impurity in the sample base fluid. Filter membrane sets up in the inside upper end of filter inferior valve, and filter membrane is located the sponge upper end, and filter membrane is used for filtering the cell. When the cell adsorption filter is used, specimen base liquid is required to be poured into the liquid storage cavity, and then the cells meeting the conditions can be adsorbed on the filter membrane after being sequentially filtered by the filter screen and the filter membrane under negative pressure. The pouring of the specimen liquid requires opening the specimen bottle of the specimen liquid, and some samples of patients may have germs in the air and cause pollution.

Based on the above problem, the utility model patent application No. 202023228558.5 (the same applicant as this case) relates to an exempt from to uncap autosegregation device, adopts this exempt from to uncap autosegregation device, and in the cell separation process, the sample bottle exempts from to uncap, and the mode of sample liquid is not poured into by the manual work, the operation of being convenient for. However, in practice, the sample bottle is spirally loaded into the separation barrel, the tip of the poking structure is positioned in the middle, and the puncture effect is not ideal during the screwing process of the sample bottle.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a three-layer type automatic sample liquid separating device, which solves the problem of poor puncture effect caused by the matching mode of a sample bottle and a separating cylinder.

In order to achieve the purpose, the utility model adopts the following technical scheme:

the utility model provides a three laminar sample liquid autosegregation devices, includes barrel, last barrel down, goes up the barrel and inserts from top to bottom with barrel down and join in marriage, is equipped with filtration membrane in the barrel down, and the upper portion of going up the barrel is equipped with the plug bush portion that supplies to exempt from to cover sample bottle plug bush, goes up to be equipped with in the barrel and disclose broken structure for disclose the tip of exempting from to cover sample bottle at exempting from to cover sample bottle plug bush in-process, disclose the sharp portion of broken structure skew go up the center of barrel.

Further, the poking structure comprises a supporting seat and a tip part positioned at the upper part of the supporting seat, and a space for the sample liquid to flow downwards is arranged between the supporting seat and the inner wall of the lower barrel body.

Furthermore, an inverted T-shaped groove is formed in the outer wall of the upper barrel body, the inverted T-shaped groove comprises a vertical slot and a rotating groove communicated with the bottom of the vertical slot, a rotating protrusion is arranged on the inner wall of the lower portion of the uncapping-free sample bottle, and the rotating groove is used for enabling the rotating protrusion to rotate and move within a set range; or the outer wall of the upper barrel body is provided with a rotating lug, the inner wall of the lower part of the uncapping-free sample bottle is provided with a T-shaped groove, the T-shaped groove comprises a vertical slot and a rotating groove communicated with the upper part of the vertical slot, and the rotating groove is used for allowing the rotating lug to rotate and move within a set range.

Further, the lower tip of exempting from to uncap sample bottle is equipped with disposable closing cap, rotatory protruding or T-slot is located disposable closing cap's downside.

Furthermore, the outer wall of the uncovering-free sample bottle is provided with a positioning hole corresponding to the position of the rotating convex or the T-shaped groove.

Furthermore, the positioning hole penetrates through the bottle body of the uncapping-free sample bottle.

Further, exempt from to uncap sample bottle includes shell and bottle chamber, and bottle chamber lower extreme is the throat portion, and bottle chamber lower extreme is equipped with disposable closing cap, rotatory protruding or T-slot setting forms annular cavity between shell and the throat portion in the shell bottom for with the plug bush portion cooperation of last barrel.

Further, the outer wall of the uncovering-free sample bottle is provided with an anti-slip structure.

Furthermore, the lower part of the upper barrel is provided with a thread structure, the upper part of the lower barrel is provided with a thread structure, and the upper barrel and the lower barrel are matched in a moving mode in the vertical direction.

Further, barrel upper portion is equipped with filtration membrane bearing structure down, and filtration membrane bearing structure includes the support otter board and is located the sponge layer on the support otter board, filtration membrane is located the upside on sponge layer.

The utility model has the beneficial effects that:

in the separation, during the film-making, the one end of the disposable closing cap of exempting from to uncap sample bottle that will contain sample liquid is down, insert on barrel upper portion, the sharp portion of the broken structure of disclosing in going up the barrel can puncture disposable closing cap and get into, the sample bottle of exempting from to uncap rotates slightly, sample liquid can flow down, sample liquid can be by exempting from to uncap in the sample bottle along disclosing the broken structure and flowing into last barrel, carry out coarse filtration through the filter screen, then further flow to filtration membrane, the cell adhesion that will need the separation is in filtration membrane department, the separating operation of required sample has been realized. Exempt from to uncap sample bottle is the relation of direct plug-in fit, and the non-screw thread is adorned soon, convenient operation, and disclose the sharp portion of breaking the structure and deviate go up the center of barrel, more do benefit to and disclose and break disposable closing cap and make sample liquid flow.

Drawings

FIG. 1 is a schematic view of the outer shape of the automatic separating apparatus of the present invention;

FIG. 2 is a cross-sectional view of the autosegregation apparatus of the present invention (with the piercing tip extending into the uncap-free sample vial);

FIG. 3 is a schematic view of a construction of a decapping-free sample vial;

FIG. 4 is a schematic view of another angle configuration of a decapped sample vial;

FIG. 5 is a schematic structural view of the upper cylinder;

FIG. 6 is a schematic view of another angular configuration of the upper barrel;

fig. 7 is a structural schematic view of the lower cylinder.

1. Exempt from to uncap sample bottle, 11, bottle lid, 12, locating hole, 13, throat portion, 14, non-skid protrusions, 15, disposable closing cap, 16, shell, 17, bottle chamber, 18, rotatory protruding, 2, go up the barrel, 21, disclose broken structure, 211, point portion, 22, the groove of falling T, 221, vertical slot, 222, rotatory groove, 23, guide way, 3, lower barrel, 31, filtration membrane bearing structure, 311, support otter board, 312, standing groove, 32, the guide strip.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.

The embodiment of the utility model comprises the following steps:

as shown in fig. 1 to 7, a three-layer type automatic sample liquid separation device includes a lower cylinder 3 and an upper cylinder 2, the upper cylinder 2 and the lower cylinder 3 are inserted and matched up and down, a filter screen (not shown) is arranged in the upper cylinder 2, a filter membrane is arranged in the lower cylinder 3, and the filter screen is positioned above the filter membrane 6. The upper part of the upper barrel body 2 is provided with a plug bush part for a plug bush of the uncapping-free sample bottle, and the upper barrel body 2 is internally provided with a poking structure 21 for poking the end part of the uncapping-free sample bottle in the process of the uncapping-free sample bottle plug bush. A filter screen for coarse filtering the sample liquid, such as filtering residues therein; a filtration membrane for filtering cells, etc., and leaving the cells to be separated at the filtration membrane.

As shown in fig. 1-4, the uncapping-free sample bottle comprises a shell 16 and a bottle cavity 17, wherein the lower end part of the bottle cavity 17 is a necking part 13, the lower end part of the bottle cavity is provided with a disposable sealing cover 15, and the upper part of the bottle cavity is opened for containing sample liquid. The upper portion of exempting from to uncap sample bottle is equipped with bottle lid 11, and is the spiral assembly, during the sample, for example get patient's sputum, open the bottle lid, screw the bottle lid after getting well, make the sample liquid of getting not expose in the air.

The shell 16 extends downwards from the connection part of the shell and the bottle cavity, and forms an annular cavity with the necking part 13, and the annular cavity is used for being matched with the plug sleeve part of the upper barrel body 2, so that the uncapping-free sample bottle 1 is plugged and sleeved on the outer side of the upper barrel body 2.

As shown in fig. 5, the breaking structure 21 includes a supporting seat and a tip 211 located at the upper portion of the supporting seat, the tip 211 of the breaking structure is offset from the center of the upper barrel 2, that is, the tip is aligned with the non-center position of the disposable cover at the bottom of the uncapping-free sample bottle, which is more beneficial to breaking the disposable cover. A space for the sample liquid to flow downwards is arranged between the supporting seat and the inner wall of the lower barrel body 3, namely, after the disposable sealing cover is broken, the sample liquid can flow downwards into the upper and lower barrel bodies 3 to be filtered for one time.

As shown in fig. 5 and 6, the outer wall of the upper cylinder 2 is provided with two inverted T-shaped grooves 22, and the two inverted T-shaped grooves 22 are arranged along the periphery of the upper cylinder 2 at 180-degree intervals. The inverted T-shaped groove 22 comprises a vertical slot 221 and a rotating groove 222 communicated with the bottom of the vertical slot 221, a rotating protrusion 18 is arranged on the inner wall of the lower part of the uncapping-free sample bottle, and the rotating groove 222 is used for allowing the rotating protrusion 18 to rotate and move within a set range, namely the uncapping-free sample bottle can rotate clockwise or anticlockwise for a set angle, so that the disposable sealing cover can be better torn; the rotary boss is positioned at the lower side of the disposable sealing cover and is arranged on the inner wall of the shell.

As shown in fig. 4, the outer wall of the uncapping-free sample bottle 1 is provided with a positioning hole 12 at a position corresponding to the rotation protrusion, and the positioning hole 12 penetrates through the body of the sample bottle, i.e., the housing. The positioning hole 12 serves as an identification function, and an operator can quickly align the positioning hole with the inverted T-shaped groove 22 of the upper cylinder body 2, so that the uncapping-free sample bottle can be quickly inserted into the upper cylinder body 2. Preferably, the positioning holes 12 are strip-shaped holes in the up-down direction. The positioning hole 12 has another function that after the uncapping-free sample bottle is inserted into the upper barrel 2, the positioning hole is communicated with the inside and the outside, pressure difference is balanced, and the downward flow of sample liquid is facilitated.

As shown in figure 1, the outer wall of the uncapping-free sample bottle is provided with an anti-skidding structure, a plurality of anti-skidding lugs 14 are adopted, and an operator is not easy to skid hands during operation.

As shown in fig. 5 and 6, the lower part of the upper cylinder 2 is provided with a thread structure, and the upper part of the lower cylinder 3 is provided with a thread structure, both of which are external threads in this embodiment, for fixedly mounting with a corresponding support plate. The thread structure is convenient to process and manufacture and is also convenient to be installed with other equipment in a matching way.

As shown in fig. 6, the upper cylinder 2 and the lower cylinder 3 are movably engaged in the vertical direction, in this embodiment, a vertical guide groove 23 is formed on the lower inner wall of the upper cylinder 2; as shown in fig. 7, the outer wall of the lower barrel 3 is provided with a guide strip 32 at a position corresponding to the guide groove, and the upper barrel 2 and the lower barrel 3 can move relatively only in the vertical direction by the cooperation of the guide groove 23 and the guide strip 32. In order to install the upper barrel body 2 conveniently, the outer wall of the upper barrel body 2 is also provided with anti-skid projections.

As shown in fig. 7, the upper part of the lower cylinder 3 is provided with a filtering membrane supporting structure 31, which includes a supporting screen 311 and a sponge layer (not shown) on the supporting screen, and the filtering membrane is located on the upper side of the sponge layer. A placing groove 312 for placing a sponge layer is formed on the supporting net plate, and the placing groove enables the filtering membrane to be positioned at the highest point of the lower barrel 3. The sponge layer has a plurality of through-hole structures, and the sample liquid after being convenient for to filter flows downwards, and the sponge layer supports filtration membrane, and under the negative pressure effect, filtration membrane is difficult to be destroyed, sets up the sponge layer moreover after, also be convenient for the epilogue shift to on the glass with the adsorbed cell of filtration membrane.

The principle of the automatic separation device of the present invention is summarized as follows:

exempt from to uncap sample bottle 1 for gather sample liquid in advance, open detachable bottle lid 11 can, cover the bottle lid after finishing, guarantee not expose in the air. In the separation, during the film-making, the one end of the disposable closing cap 15 of the sample bottle of will exempting from to uncap is down, insert on barrel 2 upper portion, the rotatory protruding 18 of the sample bottle of exempting from to uncap gets into the vertical slot 221 in the groove of falling T of barrel 2 in proper order, rotatory groove 222, the point portion 211 of disclosing the broken structure has pierced the bottom of sample bottle this moment, twist slightly again and exempt from to uncap the sample bottle, sample liquid can flow out downwards, the suction pressure of barrel 3 down cooperates simultaneously, sample liquid can flow into barrel 2 smoothly, carry out coarse filtration through the filter screen, then further flow to filtration membrane, the aperture of filtration membrane sets up to accord with and sets up the requirement, the cell that will need the separation is left in filtration membrane department, adsorb on filtration membrane surface. Next, similar to the operation in the prior art, the lower barrel 3 is detached downward relative to the upper barrel 2, the filter membrane is exposed, the slide is horizontally inserted above the filter membrane, and the lower barrel 3 is moved upward by a set distance so that the filter membrane contacts the slide to adhere the cells thereon to the slide, thereby realizing cell transfer and completing slide preparation.

In this embodiment, the disposable cover is made of aluminum foil, or a thin film, or the disposable cover of the uncapping-free sample bottle is made thin, and made thin like the sample bottle body made of the same material, and can be punctured by the puncturing structure with the tip.

In other embodiments, the outer wall of the upper cylinder body may be provided with a rotating protrusion, the inner wall of the lower portion of the sample bottle may be provided with a T-shaped groove, the T-shaped groove may include a vertical slot and a rotating groove communicated with an upper portion of the vertical slot, and the rotating groove may be used for the rotating protrusion to rotate within a set range. The T-shaped groove is positioned at the lower side of the disposable sealing cover, and the outer wall of the sample bottle is provided with a positioning hole corresponding to the T-shaped groove.

The present invention is not limited to the above-mentioned preferred embodiments, and any other products in various forms can be obtained by anyone in the light of the present invention, but any changes in the shape or structure thereof, which have the same or similar technical solutions as those of the present application, fall within the protection scope of the present invention.

Claims

1. The utility model provides a three laminar sample liquid autosegregation devices which characterized in that: the upper barrel and the lower barrel are inserted and matched up and down, a filtering membrane is arranged in the lower barrel, an inserting sleeve part for supplying an uncovering-free sample bottle inserting sleeve is arranged on the upper portion of the upper barrel, a poking-breaking structure is arranged in the upper barrel and used for poking the end part of an uncovering-free sample bottle in the uncovering-free sample bottle inserting sleeve process, and the sharp part of the poking-breaking structure is deviated from the center of the upper barrel.

2. The three-layer type automatic sample liquid separation device according to claim 1, wherein: the poking and breaking structure comprises a supporting seat and a tip part positioned on the upper part of the supporting seat, and a space for the sample liquid to flow downwards is arranged between the supporting seat and the inner wall of the lower barrel.

3. The three-layer type automatic sample liquid separation device according to claim 1, wherein: the outer wall of the upper barrel is provided with an inverted T-shaped groove, the inverted T-shaped groove comprises a vertical slot and a rotating groove communicated with the bottom of the vertical slot, the inner wall of the lower part of the uncapping-free sample bottle is provided with a rotating protrusion, and the rotating groove is used for allowing the rotating protrusion to rotate and move within a set range; or the outer wall of the upper barrel body is provided with a rotating lug, the inner wall of the lower part of the uncapping-free sample bottle is provided with a T-shaped groove, the T-shaped groove comprises a vertical slot and a rotating groove communicated with the upper part of the vertical slot, and the rotating groove is used for allowing the rotating lug to rotate and move within a set range.

4. Three-layer type sample liquid automatic separation device according to claim 3, characterized in that: the lower end of the uncapping-free sample bottle is provided with a disposable sealing cover, and the rotary convex or T-shaped groove is positioned on the lower side of the disposable sealing cover.

5. Three-layer type sample liquid automatic separation device according to claim 3, characterized in that: and the outer wall of the uncovering-free sample bottle is provided with a positioning hole corresponding to the position of the rotating convex or the T-shaped groove.

6. The three-layer type automatic sample liquid separation device according to claim 5, wherein: the positioning hole penetrates through the bottle body of the uncapping-free sample bottle.

7. The three-layer type automatic sample liquid separation device according to claim 6, wherein: exempt from to uncap sample bottle includes shell and bottle chamber, and bottle chamber lower extreme is the throat portion, and bottle chamber lower extreme is equipped with disposable closing cap, rotatory protruding or T-slot setting forms annular cavity between shell and the throat portion in the shell bottom for with the plug bush portion cooperation of last barrel.

8. The three-layer type automatic sample liquid separation device according to claim 1, wherein: the outer wall of the uncapping-free sample bottle is provided with an anti-skidding structure.

9. The three-layer type automatic sample liquid separation device according to claim 1, wherein: the lower part of the upper barrel is provided with a thread structure, the upper part of the lower barrel is provided with a thread structure, and the upper barrel and the lower barrel are matched in a moving mode in the vertical direction.

10. Three-layer type automatic separation device for sample liquid according to any one of claims 1 to 9, characterized in that: lower barrel upper portion is equipped with filtration membrane bearing structure, and filtration membrane bearing structure includes the support otter board and is located the sponge layer on the support otter board, filtration membrane is located the upside on sponge layer.