CN220597478U - Sample integral acquisition assembly - Google Patents

Abstract

The utility model discloses a sample integrated acquisition assembly, which comprises: the storage tube is internally provided with a sampler in a penetrating way, and the bottom end of the storage tube is provided with a plurality of first through holes; a collection tube, the top end of which is open, the collection tube being located below the preservation tube; the rotary sleeve, rotary sleeve's inside is provided with the division board, the division board is followed rotary sleeve's length direction extends, the division board will the inside cavity of rotary sleeve is cut apart into cavity and lower cavity, the rotatory wearing of save pipe is located in the cavity, the collecting pipe is rotatory wears to locate in the lower cavity, wherein, the second through-hole has been seted up on the division board, the second through-hole with first through-hole one-to-one sets up. The utility model realizes the integration of pretreatment operations such as sample collection, separation and the like, thereby reducing the condition that the inspector contacts the sample and improving the inspection efficiency.

Description

Sample integral acquisition assembly

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a sample integrated acquisition assembly.

Background

In the sample detection process, for biological samples (such as feces, tissue samples and the like) which need to be subjected to pretreatment operations such as grinding and the like, the samples need to be transferred from a storage tube to a grinding/treatment tube, and then the treated samples are filled into a collection tube for sealing storage. Because the whole process is manual operation, frequent sampling operation can increase the error of the sample quantity, and the condition that the sample is difficult to take out is easy to occur due to small part of samples, so that the efficiency of the subsequent sample detection is affected.

At present, there are special disposable grinding tubes and preserving tubes on the market, if the detection efficiency is to be prevented from being affected by frequent sample transfer, the grinding tubes and the preserving tubes are usually connected, and a filter membrane is arranged between the grinding tubes and the preserving tubes as a space, but the design has certain defects: the filter membrane is selected to ensure that the size and the thickness meet the requirements of intervals, and meanwhile, the sampling or oscillating amplitude in the processing process is too large, so that the filter membrane is damaged, and cross contamination or sample leakage in the sample processing process is caused.

Therefore, there is a need for a sampling device that conveniently realizes integration of pretreatment operations such as biological sample collection and separation, so that the sample collection and transfer process can be simpler and more convenient, thereby improving the detection efficiency, and avoiding the influence of sample leakage in the integration collection process on the detection efficiency.

Disclosure of Invention

The utility model mainly aims to provide a sample integrated acquisition assembly, which aims to improve the efficiency of sample detection and simultaneously avoid the problems of cross contamination or sample leakage in the sample pretreatment process.

To achieve the above object, the present utility model provides a sample integrated collection assembly, comprising: the storage tube is internally provided with a sampler in a penetrating way, and the bottom end of the storage tube is provided with a plurality of first through holes; a collection tube, the top end of which is open, the collection tube being located below the preservation tube; the rotary sleeve, rotary sleeve's inside is provided with the division board, the division board is followed rotary sleeve's length direction extends, the division board will the inside cavity of rotary sleeve is cut apart into cavity and lower cavity, the rotatory wearing of save pipe is located in the cavity, the collecting pipe wears to locate in the lower cavity, wherein, the second through-hole has been seted up on the division board, the second through-hole with first through-hole one-to-one sets up.

Optionally, the bottom of preserving the pipe is provided with first external screw thread, it is provided with first internal screw thread to go up the intracavity correspondence, rotatory sleeve with preserve through between the pipe first external screw thread with first internal screw thread connection, the top of collecting pipe is provided with the second external screw thread, it is provided with the second internal screw thread to correspond in the cavity down, rotatory sleeve with pass through between the collecting pipe second external screw thread with second internal screw thread connection.

Optionally, the preservation pipe is further provided with a pipe cover, the pipe cover is detachably connected to the top of the preservation pipe, and the bottom of the pipe cover is connected to the sampler.

Optionally, a sample metering hole is formed in the storage tube, and the sampler may partially pass through the sample metering hole.

Optionally, the lower chamber is provided with a filter, which is located above the collection tube.

Optionally, a penetrable sealing port is arranged in the collecting pipe, and the penetrable sealing port is sealed by tin foil paper or plastic packaging film.

Optionally, the sampler is one of a sampling spoon, a sampling tube and a sampling rod.

Optionally, the preservation tube is internally provided with grinding beads and preservation liquid.

The utility model has the beneficial effects that: the preservation pipe and the collecting pipe are connected through the rotary sleeve, when the pretreatment operation is needed to be carried out on the sample, the sample can be directly operated in the preservation pipe, the sample flow between the preservation pipe and the collecting pipe is controlled through the separation of the partition plate, the integration of the pretreatment operations such as biological sample collection and separation is conveniently realized, the condition that a inspector contacts the sample is reduced, and the inspection efficiency is improved.

Meanwhile, the setting of the sampler further prevents the inspector from contacting the sample to infect diseases, and the sampler is inserted into the preservation tube through the sample quantitative hole, so that preliminary uniform quantitative treatment of the sample can be realized.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic view of a sample integrated acquisition assembly according to the present utility model;

FIG. 2 is a schematic cross-sectional view of a sample integrated acquisition assembly according to an embodiment of the present utility model;

FIG. 3 is a schematic cross-sectional view of a holding tube according to an embodiment of the present utility model;

FIG. 4 is a schematic cross-sectional view of a rotary sleeve according to the present utility model;

FIG. 5 is a schematic cross-sectional view of a header of the present utility model;

FIG. 6 is a schematic cross-sectional view of a holding tube according to another embodiment of the present utility model;

FIG. 7 is a schematic cross-sectional view of another angle of the sample integral acquisition assembly of the present utility model.

Reference numerals illustrate:

a storage tube 1; a sampler 11; a first through hole 12; a first external thread 13; a tube cover 14; a sample metering hole 15; grinding beads 16; a collection tube 2; a second external thread 21; a penetrable seal 22; rotating the sleeve 3; a partition plate 31; a second through hole 32; an upper chamber 33; a lower chamber 34; a first internal thread 35; a second internal thread 36; a filter 37.

The achievement of the objects, functional features and advantages of the present utility model will be further described with reference to the accompanying drawings, in conjunction with the embodiments.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It should be noted that, if directional indications (such as up, down, left, right, front, and rear … …) are included in the embodiments of the present utility model, the directional indications are merely used to explain the relative positional relationship, movement conditions, etc. between the components in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are correspondingly changed.

In addition, if there is a description of "first", "second", etc. in the embodiments of the present utility model, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, if the meaning of "and/or" is presented throughout this document, it is intended to include three schemes in parallel, taking "a and/or B" as an example, including a scheme, or B scheme, or a scheme where a and B meet simultaneously. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present utility model.

An embodiment of the present utility model proposes a sample integrated collection assembly, referring to fig. 1 to 4, which includes a storage tube 1, a collection tube 2, and a rotation sleeve 3, wherein the storage tube 1 and the collection tube 2 are connected through the rotation sleeve 3. Specifically, a partition plate 31 is disposed inside the rotary sleeve 3, the partition plate 31 extends along the length direction of the rotary sleeve 3, the partition plate 31 divides a chamber inside the rotary sleeve 3 into an upper chamber 33 and a lower chamber 34, the holding tube 1 is rotatably inserted into the upper chamber 33, and the collecting tube 2 is inserted into the lower chamber 34. Wherein, the top end of the collecting pipe 2 is opened, a plurality of first through holes 12 are provided at the bottom end of the preservation pipe 1, a plurality of second through holes 32 are provided on the partition plate 31, and the second through holes 32 are arranged in one-to-one correspondence with the first through holes 12. In this embodiment, the storage tube 1 and the collection tube 2 are connected by the rotary sleeve 3, and when a sample needs to be subjected to pretreatment operation, the storage tube 1 can be directly operated to complete the pretreatment operation of the sample in the storage tube 1, so that the pretreatment operation integration of biological sample collection, separation and the like is realized, and the process of sample collection and transfer can be simpler and more convenient. Meanwhile, a partition plate 31 in the rotary sleeve 3 is designed to be partitioned, and the holding tube 1 is rotated relative to the rotary sleeve 3 to control the closure of the first through hole 12 and the second through hole 32, thereby controlling the sample flow between the holding tube 1 and the collecting tube 2.

In an embodiment, referring to fig. 2, a sampler 11 is disposed in the storage tube 1 in a penetrating manner, so that a inspector can place a sample into the storage tube 1, and the inspector can be prevented from contacting the sample to infect diseases.

In an embodiment, referring to fig. 3-5, a first external thread 13 is disposed at the bottom of the storage tube 1, a first internal thread 35 is correspondingly disposed in the upper chamber 33, the rotary sleeve 3 is connected with the storage tube 1 through the first external thread 13 and the first internal thread 35, a second external thread 21 is disposed at the top of the collection tube 2, a second internal thread 36 is correspondingly disposed in the lower chamber 34, and the rotary sleeve 3 is connected with the collection tube 2 through the second external thread 21 and the second internal thread 36. In this embodiment, the rotational connection between both the holding tube 1 and the collecting tube 2 and the rotating sleeve 3 is achieved by the thread shape of the respective connection. The first external thread 13 and the second external thread 21 are each a spirally convex structure, and the first internal thread 35 and the second internal thread 36 are each a spirally concave structure. When the two thread shapes are matched with each other, the connection between them can be achieved by rotating the above-mentioned male and female threads. When connecting, can produce a frictional force between external screw thread and the internal screw thread to make the connection between them more firm, be convenient for its is fixed, simultaneously, through rotatory external screw thread and internal screw thread, can realize fast save pipe 1 with collect pipe 2 both with rotatory sleeve 3 between be connected and disconnection, overall connection structure is convenient and practical.

In one embodiment, referring to fig. 3, the holding tube 1 has a built-in grinding beads 16 and a holding fluid, wherein in some sample pretreatment operations, the grinding beads 16 can help mix the sample in the holding fluid, promote the reaction, and the holding fluid can protect the sample from oxidation, decomposition, or other damage in order to hold the sample ready for subsequent analysis or operation. The sampler 11 includes, but is not limited to, one of a sampling spoon, a sampling tube, and a sampling wand.

In an embodiment, referring to fig. 3, the storage tube 1 is further provided with a tube cover 14, the tube cover 14 is detachably connected to the top of the storage tube 1, and the bottom of the tube cover 14 is fixedly connected to the sampler 11. The tube cover 14 is rotatably connected to the preservation tube 1 through threads, the sampling spoon can be selected for the sampler 11, the detachably connected preservation cover 14 can facilitate sample access in the preservation tube 1, the sampler 11 and the tube cover 14 are connected through buckling, magnetic attraction, threads and the like, the sampler 11 can be controlled to transfer or place samples through holding the tube cover 14, and the possibility of infection of diseases caused by contact of bacteria by a tester is reduced.

In another embodiment, referring to fig. 6, the holding tube 1 is provided with a sample metering hole 15, and the sampler 11 may partially pass through the sample metering hole 15. Wherein, the collector can be a sampling rod, and the sampler 11 is inserted into the preservation solution in the preservation tube 1 through the sample quantifying hole 15, so that preliminary uniform quantitative treatment of the sample can be realized.

In an embodiment, see fig. 4, the lower chamber 34 is provided with a filter 37, which filter 37 is located above the collection tube 2. Wherein the lower chamber 34 is provided with a groove for accommodating the filters 37, and a plurality of filters 37 may be provided above the collection tube 2 in order to more thoroughly filter the sample after the pretreatment operation, and the pore size and the filtering efficiency of each filter 37 may be gradually increased to filter the sample layer by layer. The sample processed in the preservation tube 1 flows into the lower part of the rotary sleeve 3 through the interval, then enters the collecting tube 2 through the filter 37, and the residue is trapped in the collecting tube 2, so that the sample residue is effectively separated, the sample collection flow is greatly simplified, and the sample after the pretreatment operation can be conveniently collected and prepared for the subsequent use together with the automatic detection equipment.

In one embodiment, referring to fig. 5, a penetrable seal 22 is disposed in the collecting tube 2, and the penetrable seal 22 is sealed by a foil or plastic sealing film. The purpose of the puncture-type sealing port 22 is to ensure the safety of the collected sample, and to facilitate the taking out and detection of the sample in the collection tube 2, and the puncture-type sealing port 22 is made of a material with certain flexibility and abrasion resistance, so that the tube can be effectively sealed, and the puncture-type sealing port is easy to tear when unsealed, so that the sample is easy to take out, and the operation is convenient and quick. In addition, the tinfoil paper and the plastic packaging film have good air tightness and moisture resistance, and can effectively prevent the sample from being oxidized and spoiled, thereby ensuring the quality of the sample.

The utility model is illustrated in more detail below by way of examples. However, the following examples are illustrative only and the scope of the present utility model should not be construed as being limited by the following examples. It will be apparent to those skilled in the art that any changes, modifications or alterations may be made without departing from the spirit of the utility model.

The sample integrated collection assembly of this example, see fig. 2-5, includes a holding tube 1, a collection tube 2, a tube cap 14, a rotating sleeve 3, and a sampling spoon. The tube cover 14 of the sample integrated acquisition assembly is connected with a sampling spoon, the tube cover 14 is connected with the preservation tube 1 through rotation, preservation liquid and grinding beads 16 are contained in the preservation tube 1, the preservation tube 1 is connected with the collection tube 2 through the rotary sleeve 3, a partition plate 31 is arranged in the rotary sleeve 3, the partition plate 31 needs to be communicated through the rotary preservation tube 1 when the hole position between the preservation tube 1 and the rotary sleeve 3 corresponds to the hole position, and therefore liquid is prevented from flowing into the collection tube 2 in advance.

When the device is used, a user can hold the tube cover 14 by hand, collect a required biological sample (faeces, tissue samples and the like) by using the sampling spoon, then the preservation tube 1 is placed in the vortex oscillator to be uniformly mixed for one minute, the sample is ensured to be uniformly dispersed in the preservation liquid, the preservation tube is kept stand for fifteen minutes, then the mixed liquid flows into the collecting tube 2 through the spaced small holes by means of gravity by rotating the preservation tube 1 to open the holes on the spacing plate 31, a filter 37 is further arranged between the rotating sleeve 3 and the collecting tube 2, and the liquid in the collecting tube 2 after the filtration is completed can be used as the sample of a nucleic acid extraction experiment.

The foregoing description is only of the optional embodiments of the present utility model, and is not intended to limit the scope of the utility model, and all the equivalent structural changes made by the description of the present utility model and the accompanying drawings or the direct/indirect application in other related technical fields are included in the scope of the utility model.

Claims (8)

1. A sample integrated acquisition assembly, comprising:

the storage tube is internally provided with a sampler in a penetrating way, and the bottom end of the storage tube is provided with a plurality of first through holes;

a collection tube, the top end of which is open, the collection tube being located below the preservation tube;

the rotary sleeve, rotary sleeve's inside is provided with the division board, the division board is followed rotary sleeve's length direction extends, the division board will the inside cavity of rotary sleeve is cut apart into cavity and lower cavity, the rotatory wearing of save pipe is located in the cavity, the collecting pipe wears to locate in the cavity down, wherein, a plurality of second through-holes have been seted up on the division board, the second through-hole with first through-hole one-to-one sets up.

2. The sample integrated collection assembly according to claim 1, wherein a first external thread is provided at the bottom of the storage tube, a first internal thread is provided in the upper chamber, the rotary sleeve is connected with the storage tube through the first external thread and the first internal thread, a second external thread is provided at the top of the collection tube, a second internal thread is provided in the lower chamber, and the rotary sleeve is connected with the collection tube through the second external thread and the second internal thread.

3. The sample integrated collection assembly of claim 1, wherein the preservation tube is further provided with a tube cap removably attached to a top of the preservation tube, and wherein a bottom of the tube cap is attached to the sampler.

4. The integrated sample collection assembly of claim 1, wherein the preservation tube has a sample metering orifice formed therein, the sampler being partially passable through the sample metering orifice.

5. The sample integrated collection assembly of claim 2, wherein the lower chamber is provided with a filter, the filter being located above the collection tube.

6. The integrated sample collection assembly of claim 1, wherein a penetrable seal is disposed within the collection tube, the penetrable seal being sealed with a foil or plastic sealing membrane.

7. The sample integrated acquisition assembly of claim 1, wherein the sampler is one of a sampling spoon, a sampling tube, and a sampling wand.

8. The sample integrated collection assembly of claim 1, wherein the preservation tube houses a polishing bead and a preservation fluid.