CN211848004U - Nucleic acid extraction instrument - Google Patents

Abstract

The utility model discloses a nucleic acid extraction appearance, including quick-witted case, material tray, a plurality of suction head, the incubation mechanism of liftable, magnetism adsorption component, hanging flower basket and guided way, be equipped with a plurality of detachable reagent boards on the material tray, all seted up sample groove, schizolysis cistern, washing cistern, elution cistern, waste liquid groove and reaction tank on every reagent board, the rear end of reagent board is located to the reaction tank. The suction head is used for transferring sample, lysate, washing liquid, eluant, waste liquid and nucleic acid, and the liquid heating in the reaction tank can be given to the temperature raising mechanism, and the magnetic force of two piece at least magnets of magnetism absorption subassembly is alternately for the magnetic force increase that the magnetic bead received, magnetism adsorb time is shorter and the effect is better. The design structure of hanging flower basket is ingenious, is convenient for take out the centrifuge tube, and avoids the centrifuge tube to interfere the change of reagent board. The steps of cracking, washing, eluting, waste liquid, transferring nucleic acid and the like of the nucleic acid are all finished in the extractor, so that the workload of personnel is reduced, and the efficiency of extracting the nucleic acid is improved.

Description

Nucleic acid extraction instrument

Technical Field

The utility model relates to a biological detection technical field, in particular to nucleic acid extraction appearance.

Background

The nucleic acid extractor is an instrument for finishing the extraction of sample nucleic acid, and is widely applied to various fields of disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microorganism detection, food safety detection, animal husbandry, molecular biology research and the like. Biological detection is more and more emphasized by people, the nucleic acid extraction step at the current stage is complex, the nucleic acid extraction step needs to be completed by cooperation of multiple devices, and the nucleic acid extraction instrument is produced at the same time, but the nucleic acid extraction instrument at the current stage can only complete partial extraction work, has a huge structure and is complex to operate, and is not beneficial to the work of quickly extracting a large amount of nucleic acid.

SUMMERY OF THE UTILITY MODEL

The utility model discloses aim at solving one of the technical problem that exists among the prior art at least. Therefore, the utility model provides a nucleic acid extraction appearance can accomplish the work of drawing of nucleic acid, easy operation, and extraction rate is fast.

According to the utility model discloses a nucleic acid extraction appearance of first aspect embodiment, including quick-witted case, material tray, a plurality of suction head, the incubation mechanism of liftable, magnetism adsorption component, hanging flower basket and guided way. The front end of the case is provided with a case door, a cavity is arranged in the case, the material tray is arranged in the cavity of the case and can slide back and forth, and the front end of the material tray corresponds to the position of the case door. The material tray is provided with a plurality of detachable reagent plates, each reagent plate is provided with a sample groove, a cracking liquid groove, a washing liquid groove, an elution liquid groove, a waste liquid groove and a reaction groove, and the reaction groove is arranged at the rear end of the reagent plate. The plurality of suction heads are arranged above the material tray, and all the suction heads can be lifted and can move back and forth. The incubation mechanism is arranged below the rear end of the material tray. The magnetic adsorption component is arranged at the rear part of the material tray and can be abutted against the side wall of the reaction tank, the magnetic adsorption component comprises at least two magnets, and the surface of each magnet is parallel to the tangent line of any point of the side wall of the reaction tank. Hanging flower basket rotationally hangs through the swing arm and locates material tray's front end, hanging flower basket are equipped with the centrifuging tube that is used for splendid attire nucleic acid, and the guided way is located material tray's below, the slope has been seted up to the front end of guided way, the hanging flower basket direct or indirect with the guided way butt.

According to the utility model discloses the subject name has following beneficial effect at least:

the suction head is used for transferring sample, lysate, washing liquid, eluant, waste liquid and nucleic acid, and the liquid heating in the reaction tank can be given to incubation mechanism, and the magnetic force of two piece at least magnets is alternately for the magnetic force increase that the magnetic bead received, magnetism adsorption time is shorter and the effect is better, and when material tray slided forward, the hanging flower basket will reduce the height, and the hanging flower basket is close to the chamber door, and the structure is ingenious, is convenient for take out the centrifuge tube, and avoids interfering the change of centrifuging tube reagent board. The steps of cracking, washing, eluting, waste liquid, transferring nucleic acid and the like of the nucleic acid are all finished in the extractor, so that the workload of personnel is reduced, and the efficiency of extracting the nucleic acid is improved.

According to the utility model discloses a some embodiments, the swing arm is kept away from the one end of material tray pass through the hinge with the hanging flower basket is connected, the one end of hinge with the upper surface butt of guided way.

According to some embodiments of the utility model, the one end of hinge is equipped with the runner, the hinge passes through the upper surface butt of runner and guided way.

According to some embodiments of the utility model, the top of machine incasement is equipped with second glide machanism, second glide machanism is connected with the lifter plate through third glide machanism, be equipped with the cylinder on the lifter plate, suction head detachably install in on the cylinder.

According to the utility model discloses a some embodiments, second glide machanism includes matched with second slide rail and second slider, the second slide rail sets up along the fore-and-aft direction, be equipped with the riser on the second slider, the lifter plate pass through the third glide machanism with the riser is connected, the second slider is connected with first linear drive mechanism.

According to the utility model discloses a some embodiments, third glide machanism includes matched with third slide rail and third slider, the third slide rail sets up on the riser, the third slide rail sets up along upper and lower direction, on the third slider was located to the lifter plate, the lifter plate was connected with first lift actuating mechanism.

According to the utility model discloses a some embodiments, the top of material tray front end is equipped with the second diaphragm, second diaphragm rear end is equipped with a plurality of U type opening, the suction head can stretch into U type opening just the up end of suction head can with the downside butt of second diaphragm.

According to some embodiments of the utility model, incubation mechanism includes first diaphragm and locates sleeve on the first diaphragm, the sleeve can hold the reaction tank, telescopic inner wall is equipped with the heating wire.

According to some embodiments of the present invention, the incubation mechanism further comprises a fourth sliding mechanism and a third lifting driving mechanism, the first transverse plate is arranged on the fourth sliding mechanism and connected with an output end of the third lifting driving mechanism.

According to the utility model discloses a some embodiments, the material tray is connected through first glide machanism bottom of quick-witted incasement, the material tray is connected with second sharp actuating mechanism.

Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.

Drawings

The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:

FIG. 1 is a first schematic diagram of a nucleic acid extractor according to an embodiment of the present invention;

FIG. 2 is a second schematic diagram of the nucleic acid extractor according to the embodiment of the present invention;

FIG. 3 is a schematic view of a test card of the nucleic acid extractor shown in FIG. 2;

FIG. 4 is a schematic diagram of a material tray, a basket and a guide rail of the nucleic acid extractor according to the embodiment of the present invention;

FIG. 5 is a schematic diagram of a pipette tip, a syringe, a vertical plate, a lifting plate, a second sliding mechanism and a third sliding mechanism of the nucleic acid extractor according to an embodiment of the present invention;

FIG. 6 is a schematic view of an incubation mechanism of the nucleic acid extractor according to the embodiment of the present invention.

Detailed Description

Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.

In the description of the present invention, it should be understood that the orientation or positional relationship indicated with respect to the orientation description, such as up, down, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

In the description of the present invention, a plurality of means are one or more, a plurality of means are two or more, and the terms greater than, less than, exceeding, etc. are understood as not including the number, and the terms greater than, less than, within, etc. are understood as including the number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.

In the description of the present invention, unless there is an explicit limitation, the words such as setting, installation, connection, etc. should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in combination with the specific contents of the technical solution.

Referring to fig. 1 and 2, a nucleic acid extractor includes a housing 100, a material tray 200, a plurality of suction heads 400, a liftable incubation mechanism 500, a magnetic adsorption assembly 600, a basket 700, and guide rails 1000. A box door is arranged at the front end of the case 100, a cavity is arranged in the case 100, the material tray 200 is arranged in the cavity of the case 100 and can slide back and forth, and the front end of the material tray 200 corresponds to the position of the box door. The material tray 200 is provided with a plurality of detachable reagent plates 300, referring to fig. 3, each reagent plate 300 is provided with a sample tank 310, a lysis liquid tank 320, a washing liquid tank 330, an elution liquid tank 340, a waste liquid tank 350 and a reaction tank 360, and the reaction tank 360 is arranged at the rear end of the reagent plate 300. The plurality of suction heads 400 are arranged above the material tray 200, all the suction heads 400 can be lifted and can move back and forth, and the suction heads 400 are used for transferring samples, lysis solution, washing solution, eluent, waste liquid and nucleic acid. The incubation mechanism 500 is disposed below the rear end of the material tray 200, and the incubation mechanism 500 heats the liquid in the reaction tank 360. Magnetic adsorption subassembly 600 locates the rear of material tray 200, and can with the lateral wall butt of reaction tank 360, magnetic adsorption subassembly 600 includes two piece at least magnets, the surface of magnet is parallel with the tangent line of any point of reaction tank 360 lateral walls. The magnetic force direction of at least two magnets is crossed, so that the magnetic force of the magnetic beads is increased, the magnetic adsorption time is shorter and the effect is better. Hanging flower basket 700 rotationally hangs the front end of locating material tray 200 through swing arm 800, hanging flower basket 700 is equipped with the centrifuging tube 900 that is used for splendid attire nucleic acid, material tray 200's below is located to guided way 1000, slope 1010 has been seted up to the front end of guided way 1000, hanging flower basket 700 is direct or indirect with guided way 1000 butt, material tray 200 when sliding forward, hanging flower basket 700 will reduce the height, hanging flower basket 700 is close to the chamber door, the structure is ingenious, be convenient for take out centrifuging tube 900, and avoid centrifuging tube 900 to interfere the change of reagent board 300. The steps of cracking, washing, eluting, waste liquid, transferring nucleic acid and the like of the nucleic acid are all finished in the extractor, so that the workload of personnel is reduced, and the efficiency of extracting the nucleic acid is improved.

Referring to fig. 4, one end of the swing arm 800 away from the material tray 200 is connected to the basket 700 through a hinge shaft 1100, and one end of the hinge shaft 1100 abuts against the upper surface of the guide rail 1000, so that the basket 700 is always horizontal under the action of gravity, and the basket 700 moves along the track of the upper surface of the guide rail 1000. In this embodiment, two swing arms 800, two guide rails 1000 and two hinge shafts 1100 are arranged, the two swing arms 800 are respectively arranged at the left side and the right side of the material tray 200, the two guide rails 1000 are respectively arranged below the left side and the right side of the material tray 200, two ends of the hanging basket 700 are respectively connected with the two swing arms 800 through the two hinge shafts 1100, the upper surfaces of the guide rails 1000 at one ends of the hinge shafts 1100 are abutted, and when the material tray 200 slides, the hanging basket 700 slides more stably. Further, the basket 700 includes a support plate and two ear plates respectively disposed at two ends of the support plate, and the ear plates are connected to the hinge shaft 1100, so that the support plate is always kept horizontal under the action of gravity, thereby preventing the nucleic acid from overflowing from the centrifuge tube 900.

Further, a rotating wheel is arranged at one end, abutted to the upper surface of the guide rail 1000, of the hinge shaft 1100, and the hinge shaft 1100 is abutted to the upper surface of the guide rail 1000 through the rotating wheel, so that friction force applied to the material tray 200 during sliding can be reduced. In another embodiment, the guide rails 1000 are disposed below the material tray 200, the upper surface of the guide rails 1000 abuts against the lower surface of the basket 700, and the basket 700 can slide on the guide rails 1000.

Referring to fig. 2 and 5, a second sliding mechanism 1200 is disposed above the chassis 100, the second sliding mechanism 1200 is connected to a lifting plate 1400 through a third sliding mechanism 1300, the lifting plate 1400 is connected to a first linear driving mechanism 2200, the first linear driving mechanism 2200 drives the lifting plate 1400 to slide back and forth, the lifting plate 1400 is further connected to a first lifting driving mechanism 2000, the first lifting driving mechanism 2000 drives the lifting plate 1400 to move up and down, a syringe 1500 is disposed on the lifting plate 1400, a piston rod of the syringe 1500 is connected to a second lifting driving mechanism 2100, and the suction head 400 is detachably mounted on the syringe 1500. Under the cooperation of the first linear driving mechanism 2200 and the first elevation driving mechanism 2000, the function of the suction head 400 extending into the sample tank 310, the lysis liquid tank 320, the washing liquid tank 330, the elution liquid tank 340, the waste liquid tank 350 or the reaction tank 360, or the function of the suction head 400 withdrawing from the sample tank 310, the lysis liquid tank 320, the washing liquid tank 330, the elution liquid tank 340, the waste liquid tank 350 or the reaction tank 360 is realized. The second elevation driving mechanism 2100 drives the piston rod of the syringe 1500, so that the function of sucking or spraying liquid by the suction head 400 can be realized, and finally, the transfer of the sample, the lysate, the washing solution, the eluent, the waste liquid or the nucleic acid can be realized, and the operation is convenient and fast.

Further, the second sliding mechanism 1200 includes a second sliding rail and a second sliding block which are matched with each other, the second sliding rail is disposed on the inner wall of the case 100, the second sliding rail is disposed along the front-back direction, a vertical plate is disposed on the second sliding block, the third sliding mechanism 1300 is disposed on the vertical plate, the first linear driving mechanism 2200 is disposed on the inner wall of the case 100, the output end of the first linear driving mechanism 2200 is connected with the second sliding block, and the first linear driving mechanism 2200 can drive the second sliding block to slide along the track of the second sliding rail, so as to drive the vertical plate and the third sliding mechanism 1300 to slide.

Third glide machanism 1300 includes matched with third slide rail and third slider, and the third slide rail sets up on the riser, and the third slide rail sets up along upper and lower direction, and lifter plate 1400 locates on the third slider, and first lift actuating mechanism 2000 locates on the riser and is connected with lifter plate 1400, and first lift actuating mechanism 2000 can drive third slider and lifter plate 1400 and go up and down on the riser. The body of the needle cylinder 1500 is connected to the lifting plate 1400, the second lifting driving mechanism 2100 is disposed on the lifting plate 1400, the output end of the second lifting driving mechanism 2100 is connected to the piston rod, and the piston rod is connected to the lifting plate 1400 through the fifth sliding mechanism. The fifth sliding mechanism comprises a fifth sliding rail and a fifth sliding block which are matched, the fifth sliding rail is arranged on the lifting plate 1400, and the fifth sliding block is connected with the piston rod.

The first elevation driving mechanism 2000, the second elevation driving mechanism 2100 and the first linear driving mechanism 2200 may include a motor, a lead screw and a lead screw nut, wherein an output end of the motor is connected to the lead screw, and the lead screw nut is disposed on the lead screw. In another embodiment, the first elevation driving mechanism 2000, the second elevation driving mechanism 2100, and the first linear driving mechanism 2200 may each be a cylinder.

In this embodiment, the number of the second sliding mechanisms 1200 is two, two second sliding rails are respectively disposed on two inner walls of the case 100, the two second sliding rails are parallel to each other, and a vertical plate is disposed on the two second sliding blocks in a straddling manner. The third glide mechanism 1300 is also provided with two, two third slide rails are arranged on the vertical plate, and the lifting plate 1400 is arranged on the two third slide blocks in a spanning manner. Such a structure can make the vertical plate and the lifting plate 1400 more stable when sliding.

Referring further to fig. 2, a second transverse plate 1600 is disposed above the front end of the material tray 200, a plurality of U-shaped openings 1700 are disposed at the rear end of the second transverse plate 1600, the suction head 400 can extend into the U-shaped openings 1700, and the upper end surface of the suction head 400 can abut against the lower side surface of the second transverse plate 1600. When the suction head 400 extends into the U-shaped opening 1700, the syringe 1500 is lifted up so that the upper end surface of the suction head 400 abuts against the lower side surface of the second transverse plate 1600, and the syringe 1500 is lifted up continuously so that the suction head 400 can fall off from the syringe 1500. The reagent plate 300 is provided with a slot for accommodating the suction head 400, and the suction head 400 can fall into the slot, so that the suction head 400 can be conveniently and quickly replaced.

Referring to FIG. 6, the incubation mechanism 500 includes a first horizontal plate 510 and a sleeve 520 disposed on the first horizontal plate 510, the sleeve 520 can accommodate the reaction tank 360, and the inner wall of the sleeve 520 is provided with heating wires not shown. The incubation mechanism 500 further comprises a fourth sliding mechanism 530 and a third lifting/lowering driving mechanism 540, wherein the first horizontal plate 510 is disposed on the fourth sliding mechanism 530 and connected to an output end of the third lifting/lowering driving mechanism 540. When the third elevating driving mechanism 540 drives the sleeve 520 to ascend and cover the reaction tank 360, the heating wire is energized to heat the liquid substance in the reaction tank 360, i.e., the incubation process, thereby accelerating the understanding of the cells. When it is not necessary to heat the contents of the reaction tank 360, the third elevating driving mechanism 540 drives the sleeve 520 to descend.

The rear of material tray 200 is located to magnetism absorption subassembly 600, and when material tray 200 moved backward, magnetism absorption subassembly 600 and reaction tank 360's lateral wall butt to carry out the magnetism and adsorb the step, the magnetic bead that will carry nucleic acid adsorbs the lateral wall at reaction tank 360.

The material tray 200 is connected to the bottom of the cavity of the chassis 100 through a first sliding mechanism 1800, the material tray 200 is connected to a second linear driving mechanism 1900, and the second linear driving mechanism 1900 drives the material tray 200 to slide back and forth. In this embodiment, there are two first sliding mechanisms 1800, the first sliding mechanisms 1800 includes a first sliding rail and a second sliding rail that are matched with each other, the two first sliding rails are disposed side by side and connected to the chassis 100, the first sliding rails are disposed along the front-back direction, and the material tray 200 is disposed across the two first sliding blocks. The second linear driving mechanism 1900 includes a motor, a lead screw, and a lead screw nut, wherein the output end of the motor is connected to the lead screw, and the lead screw nut is disposed on the lead screw and connected to the material tray 200. In another embodiment, the second linear drive mechanism 1900 is an air cylinder. In this embodiment, the material tray 200 is provided with five reagent plates 300, and further, the material tray 200 is provided with five sliding grooves one by one, each reagent plate 300 is provided with a bump, and the bump can slide in the sliding groove and can be taken out from the sliding groove.

The nucleic acid extractor comprises the following steps: the operator puts the sample liquid, the lysis solution, the washing solution and the eluent into the sample tank 310, the lysis solution tank 320, the washing solution tank 330 and the eluent tank 340 respectively in advance, wherein the lysis solution contains magnetic beads. The first linear driving mechanism 2200 and the first elevation driving mechanism 2000 drive the pipette head 400 to extend into the sample tank 310, the sample liquid is drawn into the pipette head 400 by the syringe 1500, then the pipette head 400 extends into the reaction tank 360, the syringe 1500 sprays the sample liquid into the reaction tank 360, then the pipette head 400 adds the lysis solution from the lysis solution tank 320 into the reaction tank 360, and the cells are lysed.

The second linear driving mechanism 1900 drives the material tray 200 to move backward, the third lifting driving mechanism 540 drives the incubation mechanism 500 to ascend to be close to the reaction tank 360, the incubation mechanism 500 heats the mixed liquid in the reaction tank 360, the suction head 400 continuously sucks and sprays the mixed liquid in the reaction tank 360, which is equivalent to the action of stirring the mixed liquid, the incubation and the stirring can accelerate the cracking of the liquid cells of the sample, the efficiency of extracting nucleic acid is improved, the liquid cells of the sample release impurities such as nucleic acid, protein and the like, and the nucleic acid is adsorbed on the magnetic beads to form a mixed body.

After the cell lysis is completed, the material tray 200 is driven to move backward, the reaction well 360 is close to the magnetic adsorption member 600, and the mixture is concentrated on the sidewall of the reaction well 360, thereby previously concentrating the nucleic acid in one region. The pipette tip 400 is then driven to aspirate the mixed solution in the reaction tank 360 into the waste liquid tank 350, leaving a mixture. Since the nucleic acid is concentrated in one area, the nucleic acid can be prevented from being removed by mistake when the mixed waste liquid is pumped, so that the nucleic acid can be stored in the maximum limit, and the accuracy of measuring the concentration of the nucleic acid can be improved.

Since impurities such as proteins remain when the mixed waste liquid is sucked, the pipette tip 400 is driven to feed the washing liquid into the reaction tank 360, the impurities such as proteins mixed in the mixture are diluted in the washing liquid, and the pipette tip 400 is driven again, so that the mixed waste liquid composed of the washing liquid and the impurities such as proteins is sucked into the waste liquid tank 350, thereby effectively improving the purity of nucleic acids. The reaction tank 360 may be filled with a washing solution and mixed waste solution may be removed several times. After most impurities are removed, the suction head 400 is driven to add eluent into the reaction tank 360 after washing, and the magnetic beads and nucleic acid are separated by the eluent, so that the nucleic acid can be conveniently extracted subsequently. Finally, the suction head 400 is driven to suck the nucleic acid into the centrifuge tube 900, the material tray 200 is driven to move forward, and the centrifuge tube 900 is close to the door of the box so that the centrifuge tube 900 can be conveniently taken out from the box 100.

The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.

Claims (10)

1. A nucleic acid extractor, comprising:

case (100): the front end is provided with a box door;

material tray (200): the reagent plate is arranged in the case (100) and can slide back and forth, a plurality of detachable reagent plates (300) are arranged, each reagent plate (300) is provided with a sample groove (310), a cracking liquid groove (320), a washing liquid groove (330), an elution liquid groove (340), a waste liquid groove (350) and a reaction groove (360), and the reaction groove (360) is arranged at the rear end of the reagent plate (300);

the suction heads (400) are arranged above the material tray (200), can be lifted and moved back and forth, and are used for transferring samples, lysate, washing liquid, eluent, waste liquid and nucleic acid;

liftable incubation mechanism (500): is arranged below the rear end of the material tray (200);

magnetic adsorption assembly (600): the device comprises at least two magnets, wherein the magnets are arranged behind the material tray (200) and can be abutted against the side wall of the reaction tank (360), and the surfaces of the magnets are parallel to the tangent line of any point of the side wall of the reaction tank (360);

basket (700): the material tray (200) is rotatably hung at the front end of the material tray through a swing arm (800) and is provided with a centrifugal tube (900) for containing nucleic acid;

the guide rail (1000) is arranged below the material tray (200), a slope (1010) is formed in the front end of the guide rail (1000), and the hanging basket (700) is directly or indirectly abutted to the guide rail (1000).

2. The nucleic acid extractor of claim 1, wherein: one end, far away from the material tray (200), of the swing arm (800) is connected with the hanging basket (700) through a hinge shaft (1100), and one end of the hinge shaft (1100) is abutted to the upper surface of the guide rail (1000).

3. The nucleic acid extractor of claim 2, wherein: one end of the hinge shaft (1100) is provided with a rotating wheel, and the hinge shaft (1100) is abutted to the upper surface of the guide rail (1000) through the rotating wheel.

4. The nucleic acid extractor of claim 1, wherein: the machine is characterized in that a second sliding mechanism (1200) is arranged above the inside of the machine case (100), the second sliding mechanism (1200) is connected with a lifting plate (1400) through a third sliding mechanism (1300), a needle cylinder (1500) is arranged on the lifting plate (1400), and the suction head (400) is detachably arranged on the needle cylinder (1500).

5. The nucleic acid extractor of claim 4, wherein: the second sliding mechanism (1200) comprises a second sliding rail and a second sliding block which are matched, the second sliding rail is arranged along the front-back direction, a vertical plate is arranged on the second sliding block, the lifting plate (1400) is connected with the vertical plate through a third sliding mechanism (1300), and the second sliding block is connected with a first linear driving mechanism (2200).

6. The nucleic acid extractor of claim 5, wherein: third glide machanism (1300) are including matched with third slide rail and third slider, the third slide rail sets up on the riser, the third slide rail sets up along upper and lower direction, on third slider was located to lifter plate (1400), lifter plate (1400) were connected with first lift actuating mechanism (2000).

7. The nucleic acid extractor according to any one of claims 1 to 6, wherein: the top of material tray (200) front end is equipped with second diaphragm (1600), second diaphragm (1600) rear end is equipped with a plurality of U type opening (1700), suction head (400) can stretch into U type opening (1700) just the up end of suction head (400) can with the downside butt of second diaphragm (1600).

8. The nucleic acid extractor of claim 1, wherein: the incubation mechanism (500) comprises a first transverse plate (510) and a sleeve (520) arranged on the first transverse plate (510), the sleeve (520) can accommodate the reaction tank (360), and the inner wall of the sleeve (520) is provided with an electric heating wire.

9. The nucleic acid extractor of claim 8, wherein: the incubation mechanism (500) further comprises a fourth sliding mechanism (530) and a third lifting driving mechanism (540), and the first cross plate (510) is arranged on the fourth sliding mechanism (530) and connected with the output end of the third lifting driving mechanism (540).

10. The nucleic acid extractor of claim 1, wherein: the material tray (200) is connected to the bottom in the case (100) through a first sliding mechanism (1800), and the material tray (200) is connected with a second linear driving mechanism (1900).

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