CN211751166U - Microneedle leading-in type eye patch for moisturizing - Google Patents
Microneedle leading-in type eye patch for moisturizing Download PDFInfo
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- CN211751166U CN211751166U CN201921396139.7U CN201921396139U CN211751166U CN 211751166 U CN211751166 U CN 211751166U CN 201921396139 U CN201921396139 U CN 201921396139U CN 211751166 U CN211751166 U CN 211751166U
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Abstract
The utility model provides a microneedle leading-in type eye patch for moisturizing, a serial communication port, including compound supporting layer, zone of heating, insulating layer, reservoir bed and the hyaluronic acid microneedle array layer that forms in proper order. Compared with the traditional beautifying and moisturizing mode of coating hyaluronic acid on skin, the microneedle on the patch can break through the barrier effect of the stratum corneum of the skin, form a plurality of micropore channels, greatly improve the permeation efficiency of the hyaluronic acid with large molecular weight and enhance the moisturizing effect. And moreover, the moisturizing and water replenishing effects can be further improved through the synergistic effect of the water storage layer and the heating layer.
Description
Technical Field
The utility model belongs to the technical field of beauty and skin care, in particular to a microneedle leading-in eye patch for moisturizing.
Background
Hyaluronic Acid (HA) is a unique linear macromolecular mucopolysaccharide with a molecular weight of 600000-1000000 Da. The molecular structure and the large molecular weight of the water-retaining agent enable the water-retaining agent to absorb water which is 500-1000 times of the self weight, and the water-retaining and water-retaining capacity is very excellent. Hyaluronic acid is widely distributed in various parts of the human body, is one of the main matrix components of the epidermis and dermis of the skin, and enables the skin to be in a full and compact state due to the water retention capacity of the hyaluronic acid. When the human body is aged, the amount of synthesized hyaluronic acid is reduced, resulting in lack of moisture and skin shriveling to form wrinkles. Therefore, hyaluronic acid has wide application in the field of beauty cosmetics and is often used as an epidermal moisturizer to achieve the purposes of enhancing the moisture content of skin, eliminating wrinkles and delaying aging.
However, due to the relatively high molecular weight of hyaluronic acid, it does not penetrate effectively into the dermis layer when applied externally under the barrier action of the stratum corneum of the skin, resulting in a great loss of efficacy in enhancing skin hydration. The permeability on the skin surface is usually enhanced by reducing the molecular weight, but the water retention capacity of hyaluronic acid is positively correlated with the molecular weight, and the moisture retention effect is greatly reduced after the molecular weight is reduced. On the other hand, hyaluronic acid itself does not contain moisture, but achieves a moisturizing effect by absorbing moisture in the surrounding environment (such as air, or skin), and if in a dry environment, it may suck back moisture in the skin, exacerbating skin dryness.
SUMMERY OF THE UTILITY MODEL
In view of this, the to-be-solved technical problem of the utility model lies in providing a microneedle induction type eye pad for moisturizing, the utility model provides a microneedle induction type eye pad has good moisturizing effect.
The utility model provides a microneedle induction type eye patch for moisturizing, including compound supporting layer, zone of heating, insulating layer, reservoir bed and the hyaluronic acid microneedle array layer that forms in proper order.
Preferably, the hyaluronic acid micro-needle array layer comprises a hyaluronic acid base layer and a micro-needle array arranged on the surface of the hyaluronic acid base layer, and the thickness of the hyaluronic acid base layer is 10-500 μm.
Preferably, the molecular weight of the hyaluronic acid is 10kDa to 1500 kDa.
Preferably, the diameter of the bottom of the microneedle structure is 100-1000 microns, the height of the microneedle structure is 100-2000 microns, and the distance between microneedles is 200-5000 microns.
Preferably, the material of the water storage layer is selected from one or more of hypromellose, collagen, amylopectin and polysaccharide polymer.
Preferably, the insulating layer is a polyethylene or polyvinyl chloride film, and the thickness of the insulating layer is 20-200 mu m.
Preferably, the heating layer is a heating membrane containing a metal film electric heating wire, and the temperature of the heating layer is room temperature to 43 ℃ during heating.
Preferably, the support layer is a nonwoven fabric layer.
Preferably, the area of the eye patch is about 2-10 cm2The quantity of the micro-needles on the surface of the eye patch is 2000-5000 needles per patch.
Compared with the prior art, the utility model provides a microneedle induction type eye patch for moisturizing, a serial communication port, including compound supporting layer, zone of heating, insulating layer, reservoir bed and the hyaluronic acid micropin array layer that forms in proper order. Compared with the traditional beautifying and moisturizing mode of coating hyaluronic acid on skin, the microneedle on the patch can break through the barrier effect of the stratum corneum of the skin, form a plurality of micropore channels, greatly improve the permeation efficiency of the hyaluronic acid with large molecular weight and enhance the moisturizing effect. And moreover, the moisturizing and water replenishing effects can be further improved through the synergistic effect of the water storage layer and the heating layer. The design of the water storage layer enables the hyaluronic acid layer to obtain continuous moisture supplement, inhibits the hyaluronic acid layer from reversely absorbing moisture from the skin, and realizes the long-time stable moisture supplementing and moisturizing function. The heating layer generates local heating after micro current is supplied, heat is conducted to the microneedle structure layer and the eye skin through the water storage layer, the dissolving rate of the hyaluronic acid microneedles in the skin can be increased, blood circulation is increased by means of the hot compress effect, and the absorption efficiency of hyaluronic acid is improved. The heat of the heating layer can also improve the water diffusion rate of the water storage layer, so that water can more quickly enter the dermis layer through the micropore channels of the horny layer formed after the micro-needles are dissolved. The microporous channels keep a relaxation state under the action of hot compress, and can maintain the continuous entering of water, thereby achieving a stronger water replenishing effect.
In addition, because the micro-needle has reasonable size and height design, when the micro-needle is penetrated into the stratum corneum of the skin, the micro-needle does not hurt the nerve endings and capillary vessels of the dermis, does not generate stabbing pain and bleeding, and has high user acceptance. The micro-pore channel on the skin can be automatically closed after the micro-needle patch is taken down, and the risk of wound infection is small. Convenient to use, the security is high, is applicable to the daily beauty treatment maintenance operation at home.
The microneedle patch of the utility model has simple preparation process, low cost and controllable quality, and is suitable for mass production.
Drawings
Fig. 1 is a schematic structural layering view of a microneedle-introduced eye patch for moisturizing provided by the present invention;
fig. 2 is a top view of a hyaluronic acid microneedle array layer;
fig. 3 is a local SEM photograph of the microneedle eye patch object of the present invention.
Detailed Description
The utility model provides a microneedle induction type eye patch for moisturizing, including compound supporting layer, zone of heating, insulating layer, reservoir bed and the hyaluronic acid microneedle array layer that forms in proper order.
Referring to fig. 1, fig. 1 is a schematic structural layered view of a microneedle-introduced eye patch for moisturizing provided by the present invention. In fig. 1, 1 is a microneedle array, 2 is a hyaluronic acid base layer, 3 is a water storage layer, 4 is an insulating layer, 5 is a heating layer, and 6 is a support layer.
The eye patch provided by the utility model comprises a hyaluronic acid micro-needle array layer, which is shown in fig. 2, and fig. 2 is a top view of the hyaluronic acid micro-needle array layer. The overall shape of the hyaluronic acid base layer is a crescent film, and a hyaluronic acid micro-needle array structure is uniformly distributed on the hyaluronic acid base layer and is vertical to the surface of the base layer.
The hyaluronic acid micro-needle array layer comprises a hyaluronic acid base layer and a micro-needle array arranged on the surface of the hyaluronic acid base layer. Specifically, the hyaluronic acid microneedle array layer comprises a hyaluronic acid base layer and a hyaluronic acid microneedle structure which is perpendicular to the surface of the base layer and is uniformly arranged into an array.
In the utility model, the micro-needle is in the shape of a cone, a cone-like body or a cylinder with a sharp top, the bottom is connected with the base layer, and the tip faces outwards. The diameter, height, arrangement period, arrangement mode, overall size of the patch and other parameters of the microneedle can be adjusted according to actual conditions.
The diameter of the bottom of the microneedle structure is 100-1000 mu m, the height of the microneedle structure is 100-2000 mu m, and the distance between the microneedles is 200-5000 mu m
Preferably, the diameter of the bottom of the micro-needle is 100-300 μm, the height is 300-600 μm, the curvature radius of the tip is 1-20 μm, the distance between the micro-needles is 300-500 μm,
during the application process, the micro-needle structure can leave micron-sized pores on the skin around the eyes, so that the stratum corneum barrier of the skin is broken through, and high-molecular-weight hyaluronic acid is delivered into the dermis.
The molecular weight of the hyaluronic acid is 10 kDa-1500 kDa. Preferably, the hyaluronic acid has a molecular weight of 300 kDa.
The hyaluronic acid substrate is a meniscus film in the whole shape, has flexibility and can be attached to the skin around eyes. The area is about 2-10 cm2The thickness is 10 to 500 μm. Preferably, the hyaluronic acid substrate is in the shape of a meniscus film with an area of about 4cm2The thickness was 200. mu.m.
In the eye patch, the number of the micro needles is 2000-5000 needles per patch.
The water storage layer is made of hydrogel materials, preferably one or more of hypromellose, collagen, amylopectin and polysaccharide polymers.
The insulating layer is a polyethylene or polyvinyl chloride film and is used for electric insulation between the water storage layer and the heating layer. The thickness is 20 to 200 μm. Preferably, the insulating layer has a thickness of 100 μm.
The heating layer is a heating membrane containing a metal film electric heating wire. The heating layer is heated at room temperature to 43 ℃. In the present invention, the room temperature is defined as 25 ± 5 ℃.
The base material for supporting is non-woven fabric or similar material with supporting effect.
The heating layer, the insulating layer and the water storage layer are sequentially coated and adhered on the base material and are collectively called as auxiliary functional layers.
Fig. 3 is a partial SEM photograph of the microneedle eye patch object of the present invention. The photograph is an SEM photograph of the hyaluronic acid microneedle array layer.
The utility model also provides a preparation technology of above-mentioned eye paste, it includes:
1) mixing hyaluronic acid powder with distilled water to obtain a mixture;
2) placing the mixture in an ultrasonic machine for ultrasonic treatment for 30min, and standing at room temperature for 12h to form a uniform hyaluronic acid aqueous solution;
3) performing surface treatment on a PDMS micro-needle mold with micropores, and plating a gold film on the surface, wherein the thickness of the gold film is 5 nm;
4) pouring the hyaluronic acid aqueous solution into a mold, and placing the mold in a vacuum drying oven for vacuum drying;
5) stripping and cutting after the hyaluronic acid solution is dried to form a film to obtain a hyaluronic acid microneedle structure layer, and sealing by using a sealing device after sterilization;
6) sequentially coating a water storage layer, an insulating layer and a heating layer on a non-woven fabric or a base layer made of similar materials with a supporting function to obtain an auxiliary functional layer, and sealing by using a sealing device after sterilization;
the use steps of the micro-needle eye patch of the utility model are as follows: when the hyaluronic acid microneedle structure layer is used, the hyaluronic acid microneedle structure layer is pressed inwards with the microneedle surfaces and pasted on the skin around the eyes, the auxiliary functional layer package is opened, the hydrogel surface faces inwards and covers the hyaluronic acid microneedle structure layer, and the hyaluronic acid microneedle structure layer and the hydrogel surface are tightly combined through pressing to form a water gradient to be led into the hyaluronic acid layer. Micro current is introduced through the power supply to enable the heating layer to slightly heat, and the power supply is turned off after a certain time. The application time of the eye patch is recommended to be 0.5-8 hours, wherein the electrifying time of the heating layer is recommended to be 10-60 minutes, the electrification is carried out at the beginning time of the eye patch application, and the power supply is turned off after the electrification is carried out for 10-60 minutes. So as to ensure that the hyaluronic acid is fully dissolved in the skin and achieve the best moisturizing effect. After the hyaluronic acid micro-needle structure layer and the auxiliary functional layer are used, the residual hyaluronic acid micro-needle structure layer and the auxiliary functional layer are torn off and discarded, and the face is cleaned by clean water and is smeared with moisturizing cream.
Compared with the traditional beautifying and moisturizing mode of coating hyaluronic acid on skin, the microneedle on the patch can break through the barrier effect of the stratum corneum of the skin, form a plurality of micropore channels, greatly improve the permeation efficiency of the hyaluronic acid with large molecular weight and enhance the moisturizing effect. And moreover, the moisturizing and water replenishing effects can be further improved through the synergistic effect of the water storage layer and the heating layer. The design of the water storage layer enables the hyaluronic acid layer to obtain continuous moisture supplement, inhibits the hyaluronic acid layer from reversely absorbing moisture from the skin, and realizes the long-time stable moisture supplementing and moisturizing function. The heating layer generates local heating after micro current is supplied, heat is conducted to the microneedle structure layer and the eye skin through the water storage layer, the dissolving rate of the hyaluronic acid microneedles in the skin can be increased, blood circulation is increased by means of the hot compress effect, and the absorption efficiency of hyaluronic acid is improved. The heat of the heating layer can also improve the water diffusion rate of the water storage layer, so that water can more quickly enter the dermis layer through the micropore channels of the horny layer formed after the micro-needles are dissolved. The microporous channels keep a relaxation state under the action of hot compress, and can maintain the continuous entering of water, thereby achieving a stronger water replenishing effect.
In addition, because the micro-needle has reasonable size and height design, when the micro-needle is penetrated into the stratum corneum of the skin, the micro-needle does not hurt the nerve endings and capillary vessels of the dermis, does not generate stabbing pain and bleeding, and has high user acceptance. The micro-pore channel on the skin can be automatically closed after the micro-needle patch is taken down, and the risk of wound infection is small. Convenient to use, the security is high, is applicable to the daily beauty treatment maintenance operation at home.
The microneedle patch of the utility model has simple preparation process, low cost and controllable quality, and is suitable for mass production.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (8)
1. A microneedle leading-in type eye patch for replenishing water and moisturizing is characterized by comprising a supporting layer, a heating layer, an insulating layer, a water storage layer and a hyaluronic acid microneedle array layer which are sequentially compounded.
2. The eye patch according to claim 1, wherein the hyaluronic acid micro-needle array layer comprises a hyaluronic acid base layer and a micro-needle array arranged on the surface of the hyaluronic acid base layer, and the thickness of the hyaluronic acid base layer is 10-500 μm.
3. The eye patch according to claim 2, wherein the hyaluronic acid has a molecular weight of 10kDa to 1500 kDa.
4. The eye patch according to claim 1, wherein the diameter of the bottom of the microneedle structure is 100-1000 μm, the height of the microneedle structure is 100-2000 μm, and the distance between the microneedles is 200-5000 μm.
5. The eye patch as claimed in claim 1, wherein the insulating layer is a polyethylene or polyvinyl chloride film with a thickness of 20-200 μm.
6. The eye mask according to claim 1, wherein the heating layer is a heating film containing a metal thin film heating wire, and the temperature of the heating layer is room temperature to 43 ℃ when the heating layer is heated.
7. The eye mask of claim 1, wherein the support layer is a nonwoven layer.
8. According to claim 1The eye patch is characterized in that the area of the eye patch is about 2-10 cm2The quantity of the micro-needles on the surface of the eye patch is 2000-5000 needles per patch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921396139.7U CN211751166U (en) | 2019-08-26 | 2019-08-26 | Microneedle leading-in type eye patch for moisturizing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921396139.7U CN211751166U (en) | 2019-08-26 | 2019-08-26 | Microneedle leading-in type eye patch for moisturizing |
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| Publication Number | Publication Date |
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| CN211751166U true CN211751166U (en) | 2020-10-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921396139.7U Active CN211751166U (en) | 2019-08-26 | 2019-08-26 | Microneedle leading-in type eye patch for moisturizing |
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| CN (1) | CN211751166U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797128A (en) * | 2021-08-31 | 2021-12-17 | 华南理工大学 | Thermal response type borneol-based steam instant microneedle eye mask and preparation method and application thereof |
-
2019
- 2019-08-26 CN CN201921396139.7U patent/CN211751166U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797128A (en) * | 2021-08-31 | 2021-12-17 | 华南理工大学 | Thermal response type borneol-based steam instant microneedle eye mask and preparation method and application thereof |
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