CN211505170U - Optical fiber optical device for immunofluorescence test - Google Patents
Optical fiber optical device for immunofluorescence test Download PDFInfo
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- CN211505170U CN211505170U CN201921849558.1U CN201921849558U CN211505170U CN 211505170 U CN211505170 U CN 211505170U CN 201921849558 U CN201921849558 U CN 201921849558U CN 211505170 U CN211505170 U CN 211505170U
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- 230000003287 optical effect Effects 0.000 title claims abstract description 46
- 238000012360 testing method Methods 0.000 title claims abstract description 43
- 238000010166 immunofluorescence Methods 0.000 title claims abstract description 17
- 239000013307 optical fiber Substances 0.000 title claims description 37
- 239000000835 fiber Substances 0.000 claims abstract description 21
- 230000005540 biological transmission Effects 0.000 claims description 4
- 230000005284 excitation Effects 0.000 abstract description 6
- 238000009434 installation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 9
- 238000001514 detection method Methods 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 6
- 239000011324 bead Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 2
- 230000008054 signal transmission Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
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Abstract
The utility model discloses an optic fibre optical device for immunofluorescence test, including shell and fixed apron, through screw fixed connection between shell and the fixed apron, screw fixedly connected with bottom plate is passed through to the inside of shell, the positive left and right sides of bottom plate difference fixedly connected with left double-beam axle support and right double-beam axle support, the utility model relates to an immunofluorescence technical field. This an optic fibre optical device for immunofluorescence test, through setting up optic fibre as fluorescence excitation light and receiving fluorescence signal's conduction piece, can be with on the fluorescence point of exciting light direct emission test card, also can directly convey the fluorescence signal of excitation to the sensor simultaneously and detect, need not through optical element focus processing, the cost is saved, and the sense terminal of flexible optic fibre can remove at will, all can be stable with light conduction to test card and sensor on, simultaneously because the sensor is fixed to be set up, small, the installation is convenient with the debugging.
Description
Technical Field
The utility model relates to an immunofluorescence technical field specifically is an optical fiber device for immunofluorescence test.
Background
Immunofluorescence technology, also known as the fluorescent antibody technology, is the first one developed in the labeled immunization technology. It is a technology established on the basis of immunology, biochemistry and microscope technology. Some researchers have tried to bind antibody molecules to some tracer substances and use antigen-antibody reactions to localize the antigenic substance in tissues or cells. The technology is mainly characterized in that: strong specificity, high sensitivity and high speed. The main disadvantages are: the problem of non-specific staining is not completely solved, the objectivity of result judgment is insufficient, and the technical procedure is also complicated.
The existing immunofluorescence detection device usually adopts a light source to directly irradiate emitted light onto a fluorescence point through an optical structure for fluorescence excitation, fluorescence emitted after excitation is also sent to a sensor through the optical structure, the optical structures are complex, the optical structures are composed of a plurality of optical filters, optical lenses and the like, the assembly and debugging are complex, the cost is high, the system consistency of the structure is poor, and the test error is large.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art, the utility model provides an optical fiber device for immunofluorescence test has solved the immunofluorescence detection device equipment complicacy of current laser detection formula, and the cost is higher, and the system of this kind of structure is unanimous relatively poor, and the test error is great problem also.
In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: an optical fiber optical device for immunofluorescence test comprises a shell and a fixed cover plate, wherein the shell and the fixed cover plate are fixedly connected through screws, the shell is internally and fixedly connected with a bottom plate through screws, the left side and the right side of the front surface of the bottom plate are respectively and fixedly connected with a left double-optical-shaft support and a right double-optical-shaft support, a double optical shaft is fixedly connected between the left double-optical-shaft support and the right double-optical-shaft support, the surface of the double optical shaft is sleeved with a linear bearing, the upper side and the lower side of the outer surface of the linear bearing are respectively sleeved with an optical fiber fixing seat and an optical shaft beam, the optical fiber fixing seat and the optical shaft beam are fixedly connected through screws, an optical fiber penetrates through the inner part of the optical fiber fixing seat, the left side of the front surface of the bottom plate is fixedly connected with a sensor clamping seat through screws, a sensor, and one end of the optical fiber is clamped with the front of the lamp bead through a fixing sleeve, the rear end of the optical fiber penetrates through the sensor clamping seat and extends to the inside of the sensor clamping seat, a test card fixing plate is fixedly connected between the front surfaces of the left double-optical-shaft support and the right double-optical-shaft support, and a test card is clamped inside the test card fixing plate.
Preferably, the front surface of the bottom plate and the right side of the right double-optical-shaft support are fixedly connected with a motor support through screws, and the inside of the motor support is fixedly connected with a stepping motor.
Preferably, the bottom end of the output shaft of the stepping motor penetrates through the motor support and extends to the lower part of the motor support, and the bottom end of the output shaft of the stepping motor is fixedly connected with a driving belt pulley.
Preferably, the bottom of the left double-optical-shaft support is rotatably connected with a driven belt wheel through a rotating shaft, the surface of the driven belt wheel is in transmission connection with the surface of the driving belt wheel through a belt, and the surface of the belt is fixedly connected with the bottom of the optical-shaft beam.
Preferably, the fixed cover plate is rotatably connected with a rear cover in the front of the test card.
Preferably, a microswitch is fixedly connected to the front side of the bottom of the left double-optical-shaft support.
Advantageous effects
The utility model provides an optic fibre optical device for immunofluorescence test. Compared with the prior art, the method has the following beneficial effects:
(1) the optical fiber optical device for immunofluorescence test is characterized in that an optical fiber fixing seat and an optical axis beam are respectively sleeved on the upper side and the lower side of the outer surface of a linear bearing, the optical fiber fixing seat and the optical axis beam are fixedly connected through screws, an optical fiber penetrates through the inside of the optical fiber fixing seat, the left side of the front surface of a bottom plate is fixedly connected with a sensor clamping seat through screws, a sensor is clamped in the sensor clamping seat, a lamp bead penetrates through the inside of the sensor clamping seat and is positioned above the sensor, one end of the optical fiber is clamped with the front surface of the lamp bead through a fixing sleeve, the rear end of the optical fiber penetrates through the sensor clamping seat and extends into the inside of the sensor clamping seat, a test card fixing plate is fixedly connected between the front surfaces of a left double-optical-shaft bracket and a right double-optical-shaft bracket, a test card is clamped, can directly excite the fluorescence point through optic fibre with the excitation light source, can directly convey the fluorescence of test card to the sensor simultaneously and detect, need not to handle through optical element focus, the cost is saved, the loaded down with trivial details step of a plurality of light filters and optical lens equipment debugging has been saved simultaneously, and the sense terminal of flexible optic fibre can remove at will, all can be stable with light conduction to sensor, it is convenient quick and accurate to detect, simultaneously because the sensor is fixed to be set up, the wire can not swing among the testing process, consequently, the not hard up signal transmission stability problem that leads to of wire has been avoided.
(2) The optical fiber optical device for immunofluorescence test is characterized in that a biaxial shaft is fixedly connected between a left biaxial shaft support and a right biaxial shaft support, the surface of the biaxial shaft is sleeved with a linear bearing, the upper side and the lower side of the outer surface of the linear bearing are respectively sleeved with an optical fiber fixing seat and an optical shaft beam, the optical fiber fixing seat and the optical shaft beam are fixedly connected through screws, the front side of a bottom plate is positioned on the right side of the right biaxial shaft support and is fixedly connected with a motor support through screws, a stepping motor is fixedly connected inside the motor support, the bottom end of an output shaft of the stepping motor penetrates through the motor support and extends to the lower side of the motor support, the bottom end of the output shaft of the stepping motor is fixedly connected with a driving belt wheel, the bottom of the left biaxial shaft support is rotatably connected with a driven belt wheel through a rotating shaft, the surface of the driven belt is in transmission connection with the surface of, the stepping motor is matched with the driving belt wheel and the driven belt wheel to drive the belt to transmit, the optical fiber fixing seat can be indirectly pulled to linearly reciprocate along the double optical axes through the optical axis beam, the test card can be comprehensively detected, and the structure is simple and the operation is convenient.
Drawings
FIG. 1 is a perspective view of the external structure of the present invention;
FIG. 2 is an exploded view of the structure of the present invention;
FIG. 3 is an enlarged view of a portion of the substrate of FIG. 2;
fig. 4 is a partial enlarged view of the utility model at B in fig. 2;
FIG. 5 is a perspective view of the local structure of the present invention;
FIG. 6 is a schematic diagram of a conventional laser inspection method;
fig. 7 is a schematic diagram of the optical fiber detection method of the present invention.
In the figure: the device comprises a shell 1, a fixed cover plate 2, a base plate 3, a left double-optical-shaft support 4, a right double-optical-shaft support 5, a double optical shaft 6, a linear bearing 7, an optical fiber fixing seat 8, an optical shaft beam 9, a sensor clamping seat 10, a microswitch 11, a sensor 12, an optical fiber 13, a test card fixing plate 14, a test card 15, a motor support 16, a stepping motor 17, a driving belt wheel 18, a driven belt wheel 19, a belt 20, a rear cover 21 and a lamp bead 22.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-7, the present invention provides a technical solution: an optical fiber optical device for immunofluorescence test comprises a shell 1 and a fixed cover plate 2, a rear cover 21 is rotatably connected inside the fixed cover plate 2 and located right ahead of a test card 15, the shell 1 and the fixed cover plate 2 are fixedly connected through screws, a bottom plate 3 is fixedly connected inside the shell 1 through screws, a motor support 16 is fixedly connected through screws on the front side of the bottom plate 3 and located on the right side of a right double-optical-shaft support 5, a stepping motor 17 is fixedly connected inside the motor support 16, the shell 1 is further provided with a circuit board for connecting the stepping motor 17, a microswitch 11 and a sensor 12, the bottom end of an output shaft of the stepping motor 17 penetrates through the motor support 16 and extends to the lower side of the motor support 16, a driving belt wheel 18 is fixedly connected to the bottom end of the output shaft of the stepping motor 17, a left double-optical-shaft support 4 and a right double-optical-shaft support 5 are fixedly connected to the, and a biaxial shaft 6 is fixedly connected between the left biaxial shaft support 4 and the right biaxial shaft support 5, the bottom of the left biaxial shaft support 4 is rotatably connected with a driven belt wheel 19 through a rotating shaft, the surface of the driven belt wheel 19 is in transmission connection with the surface of a driving belt wheel 18 through a belt 20, the surface of the belt 20 is fixedly connected with the bottom of an optical shaft beam 9, a stepping motor 17 is matched with the driving belt wheel 18 and the driven belt wheel 19 to drive the belt 20 to transmit, the optical fiber fixing seat 8 can be indirectly pulled to linearly reciprocate along the biaxial shaft 6 through the optical shaft beam 9, the test card 15 can be comprehensively detected, the structure is simple, the operation is convenient, a microswitch 11 is fixedly connected at the front side of the bottom of the left biaxial shaft support 4, when the optical shaft beam 9 touches the microswitch 11, the stepping motor 17 can be controlled to rotate reversely, a linear bearing 7 is sleeved on the surface of the biaxial shaft 6, the upper side and the lower side of the outer surface of the, and pass through screw fixed connection between optic fibre fixing base 8 and the optical axis roof beam 9, optic fibre 13 has been run through to the inside of optic fibre fixing base 8, screw fixed connection has sensor cassette 10 is passed through to the positive left side of bottom plate 3, and the inside joint of sensor cassette 10 has sensor 12, the inside of sensor cassette 10 and the top through connection who is located sensor 12 have lamp pearl 22, and the one end of optic fibre 13 and the front of lamp pearl 22 are through fixed cover joint, sensor 12 is the dedicated optical element of fluorescence detection, the rear end of optic fibre 13 runs through sensor cassette 10 and extends to the inside of sensor cassette 10, fixedly connected with test card fixed plate 14 between the front of two optical axis mount 4 in a left side and two optical axis mount 5 in a right side, and the inside joint of test card fixed plate 14 has test card 15.
Referring to fig. 5-6, can see the difference of traditional technological means with the technical means that the utility model adopts, the utility model discloses a technological means through set up optic fibre 13 as fluorescence excitation light and the conduction piece of receiving fluorescence signal, can directly convey the fluorescence of test card 15 to sensor 12 and detect, need not through optical element focus processing, the cost is saved, and the sense terminal of flexible optic fibre 13 can remove at will, all can be stable with light conduction to sensor 12, it is convenient quick to detect, simultaneously because sensor 12 is fixed to be set up, the wire can not swing in the testing process, consequently, the not hard up signal transmission stability problem that leads to of wire has been avoided.
When the device is used, the rear cover 21 is opened, the test card 15 is placed into the test card fixing plate 14 from an opening behind the rear cover 21, then the rear cover 21 is covered, the device is powered on and started, the stepping motor 17 drives the driving belt wheel 1 to rotate, the belt 20 is driven to rotate by matching with the driven belt wheel 19, the optical axis beam 9 and the optical fiber fixing seat 8 on the optical axis beam are pulled to move leftwards, the front end of the optical fiber 13 scans the test card 15, meanwhile, the lamp beads 22 emit light, the light excites the test card through the optical fiber 13, fluorescence reflected by the test card is transmitted to the sensor 12 through the optical fiber 13 for induction detection, then detection data are transmitted out, after scanning, the optical axis beam 9 touches the micro switch 11, the circuit changes, the stepping motor 17 is controlled to rotate reversely to reset the optical fiber fixing seat 8, once detection is finished, the device is closed, and the rear.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. An optical fiber optical device for immunofluorescence test, includes shell (1) and fixed apron (2), pass through screw fixed connection between shell (1) and the fixed apron (2), its characterized in that: the sensor comprises a shell (1), wherein a bottom plate (3) is fixedly connected in the shell (1) through screws, the left side and the right side of the front of the bottom plate (3) are respectively and fixedly connected with a left double-optical-shaft support (4) and a right double-optical-shaft support (5), a double optical shaft (6) is fixedly connected between the left double-optical-shaft support (4) and the right double-optical-shaft support (5), a linear bearing (7) is sleeved on the surface of the double optical shaft (6), an optical fiber fixing seat (8) and an optical shaft beam (9) are respectively sleeved on the upper side and the lower side of the outer surface of the linear bearing (7), the optical fiber fixing seat (8) and the optical shaft beam (9) are fixedly connected through screws, an optical fiber (13) penetrates through the optical fiber fixing seat (8), a sensor clamping seat (10) is fixedly connected on the left side of the front of the bottom, the inside of sensor cassette (10) and the top through connection who is located sensor (12) have lamp pearl (22), and the one end of optic fibre (13) and the front of lamp pearl (22) are through fixed cover joint, the rear end of optic fibre (13) runs through sensor cassette (10) and extends to the inside of sensor cassette (10), fixedly connected with test card fixed plate (14) between the front of left side double-pivot mount (4) and right side double-pivot mount (5), and the inside joint of test card fixed plate (14) has test card (15).
2. The fiber optic device of claim 1, wherein: the front of the bottom plate (3) is located on the right side of the right double-optical-shaft support (5) and is fixedly connected with a motor support (16) through screws, and a stepping motor (17) is fixedly connected inside the motor support (16).
3. The fiber optic device of claim 2, wherein: the bottom end of the output shaft of the stepping motor (17) penetrates through the motor support (16) and extends to the lower part of the motor support (16), and the bottom end of the output shaft of the stepping motor (17) is fixedly connected with a driving belt wheel (18).
4. The fiber optic device of claim 1, wherein: the bottom of the left double-optical-axis support (4) is rotatably connected with a driven belt wheel (19) through a rotating shaft, the surface of the driven belt wheel (19) is in transmission connection with the surface of the driving belt wheel (18) through a belt (20), and the surface of the belt (20) is fixedly connected with the bottom of the optical-axis beam (9).
5. The fiber optic device of claim 1, wherein: the inner part of the fixed cover plate (2) is positioned right ahead the test card (15) and is rotationally connected with a rear cover (21).
6. The fiber optic device of claim 1, wherein: the front side of the bottom of the left double-optical-shaft support (4) is fixedly connected with a microswitch (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921849558.1U CN211505170U (en) | 2019-10-30 | 2019-10-30 | Optical fiber optical device for immunofluorescence test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921849558.1U CN211505170U (en) | 2019-10-30 | 2019-10-30 | Optical fiber optical device for immunofluorescence test |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211505170U true CN211505170U (en) | 2020-09-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921849558.1U Active CN211505170U (en) | 2019-10-30 | 2019-10-30 | Optical fiber optical device for immunofluorescence test |
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| Country | Link |
|---|---|
| CN (1) | CN211505170U (en) |
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- 2019-10-30 CN CN201921849558.1U patent/CN211505170U/en active Active
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Effective date of registration: 20240525 Address after: 610051 Room 601, 6 / F, unit 2, building 1, No. 2-18, Jianshe Road, Chenghua District, Chengdu, Sichuan Patentee after: Zhong Hao Country or region after: China Address before: 300400 Tianjin Medical Equipment Industrial Park, Qingguang Village, Beichen District, Tianjin Patentee before: TIANJIN PAIPU DAYE INSTRUMENT TECHNOLOGY Co.,Ltd. Country or region before: China |