CN211235882U

CN211235882U - Multi-channel microplate reader

Info

Publication number: CN211235882U
Application number: CN201921954895.7U
Authority: CN
Inventors: 张无量
Original assignee: Wuhan Kangzhu Biotechnology Co ltd
Current assignee: Wuhan Kangzhu Biotechnology Co ltd
Priority date: 2019-11-13
Filing date: 2019-11-13
Publication date: 2020-08-11
Anticipated expiration: 2029-11-13

Abstract

The utility model discloses a multi-channel ELIASA, which comprises a device box body, an LED light source, an ELIAS pore plate, a photoelectric detector and a display; the device is characterized in that a box cover plate is hinged to the device box body, a display is arranged in the box cover plate, the LED light source is arranged on the left side of the device box body, the enzyme-labeled pore plate and the photoelectric detector are arranged on the right side of the device box body, multi-channel optical fibers are arranged between the LED light source and the enzyme-labeled pore plate, a multi-channel optical fiber optical signal receiving end is connected with the LED light source, multi-channel optical fiber optical signal output ends are respectively arranged under the enzyme-labeled pore plate, and the photoelectric detector is connected with the display through a connecting wire. The utility model discloses a LED light source, the light source is stable, and light source intensity is high, and light signal decay is little, and a plurality of detection samples can be placed to the ELIAS plate upper surface that sets up simultaneously, and it is high to detect the precision, once can detect a plurality of samples, has effectively improved the detection efficiency among the in-service use process.

Description

Multi-channel microplate reader

Technical Field

The utility model relates to a medical treatment detects technical field, concretely relates to multichannel ELIASA.

Background

The enzyme-linked immunosorbent assay device is a professional instrument for reading and analyzing the results of enzyme-linked immunosorbent assay. The enzyme-linked immunosorbent assay is carried out by enzyme-catalyzed chromogenic substrates coupled on antigens or antibodies, the reaction result is displayed in color, and the concentration of the antibodies or the antigens to be detected in a sample can be judged by the depth of color development, namely the magnitude of absorbance value.

The microplate reader is widely applied to clinical examination, biological research, agricultural science, food and environmental science, and particularly in recent years, due to the application of a large number of enzyme-linked immunoassay kits, the microplate reader is more and more widely applied to the reproductive health care field, and meanwhile, the reproductive health technical level is promoted to be improved.

The working principle of the microplate reader is as follows: the specimen is placed on the ELISA plate, the ELISA plate is placed on an ELISA tray of the detection box, and the motor drives the ELISA tray to move. The composite light emitted by the light source lamp is filtered and then conducted to the detection body group of the detection box through the optical fiber, the detection body group is generally provided with a plurality of detection channels, and the light passing through each channel is changed into a beam of monochromatic light. The ELIAS plate is driven by the ELIAS tray to move, so that a sample hole for placing a sample on the ELIAS plate is aligned with a detection channel of a detection body group, monochromatic light passes through the sample to be detected, one part of the monochromatic light is absorbed by the sample, the other part of the monochromatic light penetrates through the sample to irradiate the photoelectric detector, the photoelectric detector converts light signals with different intensities into corresponding electric signals due to different color development of the sample to be detected, the electric signals are sent into the microprocessor for data processing and calculation to obtain light density values or concentration values and the like after signal processing such as amplification and analog-to-digital conversion, and finally, the result is displayed by the display or. However, the existing detection box body is not stable enough when easily causing the enzyme labeling tray to move left and right, the precision is not high enough, the detection speed is slow, the ELISA plate is not perpendicular to the detection channel, and the dark environment instability of detection is influenced by external light greatly to affect the detection effect.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a multichannel ELIASA can effectively solve current ELIASA and detect the problem that the precision is low, detection speed is slow.

In order to solve the technical problem, the utility model adopts the following technical scheme:

a multi-channel microplate reader comprises a device box body, an LED light source, an elisa pore plate, a photoelectric detector and a display; the device is characterized in that a box cover plate is hinged to the device box body, a display is arranged in the box cover plate, the LED light source is arranged on the left side of the device box body, the enzyme-labeled pore plate and the photoelectric detector are arranged on the right side of the device box body, the photoelectric detector is arranged right above the enzyme-labeled pore plate, multi-channel optical fibers are arranged between the LED light source and the enzyme-labeled pore plate, a multi-channel optical fiber optical signal receiving end is connected with the LED light source, multi-channel optical fiber optical signal output ends are respectively arranged right below the enzyme-labeled pore plate, and the photoelectric detector is connected with the display through a connecting wire.

Further, a light source switch and a light intensity regulator are further arranged on the LED light source mounting plate, and a light reflection plate is further arranged on the LED light source mounting plate.

Furthermore, an optical filter plate is arranged between the multichannel optical fiber optical signal receiving end and the LED light source, and the optical filter plate is movably arranged on the side wall of the device box body.

Furthermore, the enzyme-labeled pore plate is arranged on the pore plate chute, a sample holding cavity is arranged on the enzyme-labeled pore plate, the sample holding cavity is of a detachable structure, and the joint of the enzyme-labeled pore plate and the photoelectric detector is sealed.

Furthermore, a clamping structure is arranged on the side wall of the box body cover plate, a locking mechanism is arranged on the side wall of the box body of the device, and a device handle is arranged on the upper surface of the box body cover plate.

Compared with the prior art, the utility model discloses following beneficial effect has:

the utility model adopts the LED light source, the light source is stable, the light source intensity is high, the multichannel optical fiber is adopted as the propagation medium system of the light, the attenuation of the light signal is small, and the light can be accurately and stably transmitted to the lower part of the enzyme-labeled pore plate; a plurality of detection samples can be placed on the enzyme-labeled pore plate that sets up simultaneously, need examine time measuring, only need place the sample behind the insertion device box on the enzyme-labeled pore plate, can accomplish and detect, detect the precision height, once can detect a plurality of samples, effectively improved the detection efficiency among the in-service use process.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention.

Fig. 2 is a schematic structural diagram of a top view of the present invention.

Fig. 3 is a schematic structural diagram of the front view of the present invention.

In the figure: 1-box cover plate, 2-display, 3-photoelectric detector, 4-enzyme labeled pore plate, 5-device box, 6-LED light source, 7-light source switch, 8-light intensity regulator, 9-light filter plate and 10 multi-channel optical fiber.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Example 1

A multi-channel microplate reader comprises a device box body 5, an LED light source 6, an elisa pore plate 4, a photoelectric detector 3 and a display 2; the device comprises a device box body 5, a box body cover plate 1, a display 2, a light source mounting plate, an LED light source 6, a light reflection plate, a light source switch 7, a light intensity regulator 8, a light source switch, a light intensity regulator 8, a light reflection plate, a light source, an enzyme-labeled pore plate 4 and a photoelectric detector 3, wherein the box body cover plate 1 is hinged on the device box body 5, the display 2 is arranged in the box body cover plate 1, the light source mounting plate is arranged on the left side of the device box body 5, the LED light source 6 is connected with an external power supply, the light source switch 7 and the light intensity regulator 8 are arranged on the LED light source mounting plate 6, the LED light source is provided with a plurality of intensity levels, the light intensity can be regulated through the light intensity regulator 8 so, the detection device is characterized in that a multi-channel optical fiber 10 is arranged between the LED light source 6 and the enzyme-labeled pore plate 4, an optical signal receiving end of the multi-channel optical fiber 10 is connected with the LED light source 6, optical signal output ends of the multi-channel optical fiber 10 are respectively arranged under the enzyme-labeled pore plate 4, the light source is effectively transmitted to the enzyme-labeled pore plate 4 through the multi-channel optical fiber 10, an optimal mounting point of each detection device is arranged in the space of the box body of the effective combination device, the number of output ports of the multi-channel optical fiber 10 is set according to the number of pore plates on the enzyme-labeled pore plate 4, illumination of each sample is ensured, the photoelectric detector 3 is connected with the display 2 through a connecting wire, and a detection result is transmitted to the display 2 to be displayed. The multichannel microplate reader can effectively avoid the heat generated by the light source from influencing the temperature of the sample, avoids influencing the accuracy of enzyme activity and immunoassay result determination, can detect a plurality of samples at one time, displays the sample result according to corresponding sample information, and effectively improves the detection precision and detection efficiency of the microplate reader.

Example 2

On embodiment 1's basis, be provided with light filter plate 9 between multichannel optic fibre 10 light signal receiving terminal and the LED light source 6, light filter plate 9 can be changed according to the detection demand, light filter plate 9 activity sets up on the lateral wall of device box 5, and the light filter plate 9 that sets up can be according to the light filtration that the detection demand sent the light source for monochromatic light, is adapted to the detection of all kinds of samples, improves and detects the precision.

Example 3

On the basis of embodiment 1-2, enzyme-labeled orifice plate 4 sets up on the orifice plate spout, is provided with sample holding chamber on the enzyme-labeled orifice plate 4, and sample holding chamber sets up to detachable structure, and enzyme-labeled orifice plate 4 sets up with 3 junctions of photoelectric detector are sealed, and the orifice plate wall sets up to lighttight material, can prevent adjacent sample detection mutual interference, avoids the interference of other light simultaneously, and sample holding chamber is once detected the back direct replacement and is carried out the standard and wash, puts into new sample holding chamber and detects again, has avoided the sample solution to remain the condition that causes cross contamination.

Example 4

On the basis of the embodiment 1-3, the side wall of the box cover plate 1 is provided with the clamping structure, the side wall of the device box 5 is provided with the locking mechanism, the upper surface of the box cover plate 1 is provided with the device handle, the microplate reader is compact in structure and small in size, and the locking mechanism and the handle are convenient to carry, so that the microplate reader has high popularization value.

Reference throughout this specification to embodiments means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment described generally in this application. The appearances of the same phrase in various places in the specification are not necessarily all referring to the same embodiment. Further, when a particular feature, structure, or characteristic is described in connection with any embodiment, it is submitted that it is within the scope of the invention to effect such feature, structure, or characteristic in connection with other embodiments.

Although the invention has been described herein with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this invention. More specifically, various variations and modifications are possible in the component parts and/or arrangements of the subject combination arrangement within the scope of the disclosure, the drawings and the appended claims. In addition to variations and modifications in the component parts and/or arrangements, other uses will also be apparent to those skilled in the art.

Claims

1. A multi-channel microplate reader comprises a device box body (5), an LED light source (6), an elisa pore plate (4), a photoelectric detector (3) and a display (2); the device box (5) is articulated with a box cover plate (1), and a display (2) is arranged in the box cover plate (1), and is characterized in that: the device is characterized in that the LED light source (6) is arranged on the left side of the device box body (5), the enzyme-labeled pore plate (4) and the photoelectric detector (3) are arranged on the right side of the device box body (5), the photoelectric detector (3) is arranged right above the enzyme-labeled pore plate (4), the multi-channel optical fiber (10) is arranged between the LED light source (6) and the enzyme-labeled pore plate (4), the optical signal receiving end of the multi-channel optical fiber (10) is connected with the LED light source (6), the optical signal output end of the multi-channel optical fiber (10) is respectively arranged right below the enzyme-labeled pore plate (4), and the photoelectric detector (3) is connected with the display (2) through a connecting wire.

2. The multi-channel microplate reader of claim 1, wherein: the LED light source (6) mounting plate is further provided with a light source switch (7) and a light intensity regulator (8), and the LED light source (6) mounting plate is further provided with a light reflection plate.

3. The multi-channel microplate reader of claim 1, wherein: an optical filter plate (9) is arranged between the optical signal receiving end of the multi-channel optical fiber (10) and the LED light source (6), and the optical filter plate (9) is movably arranged on the side wall of the device box body (5).

4. The multi-channel microplate reader of claim 1, wherein: the ELISA plate (4) is arranged on the plate chute, a sample holding cavity is arranged on the ELISA plate (4), the sample holding cavity is of a detachable structure, and the joint of the ELISA plate (4) and the photoelectric detector (3) is sealed.

5. The multi-channel microplate reader of claim 1, wherein: the clamping structure is arranged on the side wall of the box body cover plate (1), the locking mechanism is arranged on the side wall of the device box body (5), and the device handle is arranged on the upper surface of the box body cover plate (1).