CN216411319U

CN216411319U - Multi-channel light path structure for dry biochemical detection and biochemical detection equipment thereof

Info

Publication number: CN216411319U
Application number: CN202122911432.6U
Authority: CN
Inventors: 祝启鹏; 张小三; 戴思维
Original assignee: Getein Biotech Inc
Current assignee: Getein Biotech Inc
Priority date: 2021-11-25
Filing date: 2021-11-25
Publication date: 2022-04-29
Anticipated expiration: 2031-11-25

Abstract

The utility model relates to a multi-channel light path structure for dry biochemical detection and biochemical detection equipment thereof, which comprises a light source module, a light conduction element and a detection module, wherein one or more detection units are arranged on the detection module, each detection unit comprises an incident channel and a reflection channel, a convex lens is arranged on the incident channel, and a photocell is arranged on the reflection channel; the light source module comprises a light source, one end of the light conduction element is connected with the light source, and the other end of the light conduction element is connected with the incident channel of the detection unit. The light source module and the detection module are connected through the light conduction element, and the light source module and the detection module can be flexibly arranged, so that the whole structure is more compact. The detection module can be provided with a plurality of detection units, the light source is divided into a plurality of paths by adopting a plurality of paths of optical fiber light guide beams, high-efficiency detection of a plurality of items can be carried out in the same time period, the same type of dry detection is high in efficiency, the items which can be detected are more in the same sample size, and the detection flux is greatly improved.

Description

Multi-channel light path structure for dry biochemical detection and biochemical detection equipment thereof

Technical Field

The utility model belongs to the field of in-vitro diagnostic devices in diagnostic medicine, and particularly relates to a light path structure in dry biochemical detection and biochemical detection equipment containing the light path structure.

Background

Biochemical analysis is one of the important tools commonly used in clinical diagnosis. Various biochemical indexes are measured by analyzing blood or other body fluids, and comprehensive analysis is performed by combining with other clinical data, so that the diagnosis of the types of diseases is facilitated, the organ functions are evaluated, and concurrent factors can be identified, the standard of subsequent treatment can be determined, and the like.

The dry biochemical detection device is mainly used for the quantitative determination of biochemical and chemical components of other body fluid samples such as clinical blood, urine, serum and the like, such as hemoglobin, cholesterol, triglyceride, albumin, C-reactive protein, glucose, uric acid and the like, and is one of the most common clinical instruments.

In clinical practice, the number of samples for hospital test and analysis is rapidly increasing, and new detection items are increasing, so that the traditional manual operation scheme cannot meet the clinical use requirement. Therefore, various biochemical analyzers have been developed. Generally, a wet chemical formula and a dry chemical formula can be classified according to whether a chemical reaction between a sample and a reagent is a solid phase chemical reaction. Wherein, dry chemistry adopts the solid phase reagent technology of multilayer film, only needs to add the liquid sample into the reagent carrier solidified in the special structure, namely the dry reagent, and takes the water in the sample as the solvent, and after dissolving the reagent solidified on the carrier, the reagent reacts with the component to be measured in the sample, thereby carrying out analysis and determination.

In recent years, dry biochemical instruments have been developed rapidly due to the characteristics of rapid and convenient operation, such as reflotron plus type dry biochemical instrument of Roche and 4000ie full-automatic dry biochemical analyzer of FUJIFILM, which adopt dry chemistry methods, and when the instrument is used, a sample is only required to be added on a solid phase carrier dry reagent strip for subsequent determination without a traditional pipeline system. The dry reagent structure is generally divided into a diffusion layer, a filter layer, a reagent layer, a color development layer and a support layer from top to bottom.

In clinical practice, one patient often needs to perform several dry biochemical tests, and the number of patients to be tested is huge, and the current method is to put samples on a dry test instrument one by one for each item test, so that the manual operation cost is high, and the test flux is low.

SUMMERY OF THE UTILITY MODEL

The utility model overcomes the defects in the prior art and provides a multi-channel optical path structure for dry biochemical detection and biochemical detection equipment thereof, which can improve the detection flux.

The specific technical scheme of the utility model is as follows:

a multi-channel light path structure for dry biochemical detection comprises a light source module, a light conduction element and a detection module, wherein one or more detection units are arranged on the detection module, each detection unit comprises an incident channel and a reflection channel, a convex lens is arranged on the incident channel, and a photocell is arranged on the reflection channel;

the light source module comprises a light source, one end of the light conduction element is connected with the light source, and the other end of the light conduction element is connected with the incident channel of the detection unit.

Preferably, a heat dissipation assembly is arranged on one side of the light source away from the light conduction element.

Preferably, the heat dissipation assembly comprises a fan and a heat dissipation fin, one side of the heat dissipation fin is connected with the fan, and the other side of the heat dissipation fin is connected with the light source.

Preferably, a sealing ring is arranged on one side of the convex lens, which is located on the light conduction element, and a gasket is arranged on one side of the convex lens, which is far away from the light conduction element.

Preferably, a detection unit is arranged on the detection module, and the light conduction element is an optical fiber.

Preferably, the detection module is provided with at least 2 detection units.

Preferably, the light conduction element is a multi-path optical fiber light conduction bundle, the multi-path optical fiber light conduction bundle comprises an optical fiber connector and multi-path light conduction optical fibers connected with the optical fiber connector, an optical fiber coupler is arranged in the optical fiber connector, the number of the multi-path light conduction optical fibers corresponds to the number of the detection units one by one, the optical fiber connector is connected with the light source, and one ends, far away from the optical fiber connector, of the multi-path light conduction optical fibers are connected with the incident channels in the detection units one by one.

Preferably, the detection module is provided with 4 detection units, and the light conduction element is a four-path optical fiber light guide bundle.

The utility model also relates to biochemical detection equipment which adopts the multi-channel optical path structure.

The light source module and the detection module are connected through the light conduction element, and the light source module and the detection module can be flexibly arranged, so that the whole structure is more compact. The detection module can be provided with a plurality of detection units, the light source is divided into a plurality of paths by adopting a plurality of paths of optical fiber light guide beams, high-efficiency detection of a plurality of items can be carried out in the same time period, the same type of dry detection is high in efficiency, the items which can be detected are more in the same sample size, and the detection flux is greatly improved.

Drawings

In order to more clearly illustrate the technical solution of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious to those skilled in the art that other drawings can be obtained according to the drawings without any inventive exercise.

FIG. 1 is a schematic structural view of a biochemical detection apparatus according to the present invention;

FIG. 2 is a schematic structural diagram of a light source module according to the present invention;

FIG. 3 is an exploded view of FIG. 2;

FIG. 4 is a schematic view of the structure of the detection module and the light-conducting component according to the present invention;

fig. 5 is a cross-sectional view of fig. 4.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention and the accompanying drawings. It is to be understood that the described embodiments are merely exemplary of the utility model, and not restrictive of the full scope of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. The technical solutions provided by the embodiments of the present invention are described in detail below with reference to the accompanying drawings, and all the parts of the present invention not mentioned are prior art.

Referring to fig. 2 to 5, the utility model relates to a multi-channel light path structure for dry biochemical detection, which comprises a light source module 3, a light transmission element 4 and a detection module 1, wherein one or more detection units are arranged on the detection module 1, each detection unit comprises an incident channel 1-3 and a reflection channel 1-9, a convex lens 1-7 is arranged on the incident channel 1-3, the convex lens 1-7 is arranged on a lens mounting seat 1-1, and a photocell 1-6 is arranged on the reflection channel 1-9. The light source module 3 is arranged on the mounting bracket 3-1, the light source module 3 comprises a light source 3-6, one end of the light conduction element 4 is connected with the light source 3-6, and the other end of the light conduction element is connected with the incident channel 1-3 of the detection unit. The angle α between the incident channel 1-3 and the reflected channel 1-9 may be any value conventional in the art.

Furthermore, a heat dissipation component is arranged on one side of the light source 3-6 away from the light conduction element 4, so that the heat dissipation of the light source 3-6 is facilitated.

Furthermore, the heat dissipation assembly comprises a fan 3-4 and a heat dissipation fin 3-3, the heat dissipation fin 3-3 can adopt an aluminum-based heat dissipation fin, the fan 3-4 is connected with one side of the heat dissipation fin 3-3 through a screw 3-7, and the light source 3-6 is connected with the other side of the heat dissipation fin 3-3 through a screw 3-7.

Furthermore, a sealing ring 1-8 is arranged on one side of the convex lens 1-7, which is positioned on the light transmission element 4, so that on one hand, the protection effect is achieved, and on the other hand, the concentricity of the convex lens 1-7 and the incident channel 1-3 is ensured; the side of the convex lenses 1-7 facing away from the light-conducting element 4 is provided with a gasket (not shown) to ensure a stable position of the convex lenses 1-7.

Furthermore, the detection module 1 is provided with a detection unit, the light conduction element 4 is an optical fiber, one end of the optical fiber is connected with the light sources 3-6, and the other end of the optical fiber is connected with the incident channels 1-3 of the detection unit. The optical fiber is connected with the light source module and the detection module, and the light source module and the detection module can be flexibly placed, so that the whole structure is more compact.

Furthermore, the detection module is provided with at least 2 detection units, so that multiple items of efficient detection can be performed in the same time period, and the detection efficiency is improved.

Further, the light conduction element 4 is a multi-path optical fiber light conduction bundle, the multi-path optical fiber light conduction bundle includes an optical fiber connector 4-1 and a multi-path light conduction optical fiber 4-2 connected with the optical fiber connector 4-1, an optical fiber coupler (not shown in the figure) is arranged in the optical fiber connector 4-1, and the number of the multi-path light conduction optical fibers 4-2 corresponds to the number of the detection units one to one. The specific structure of the multi-fiber light guide bundle can be found in patent document CN 213091939U. When the multi-path optical fiber light guide bundle is adopted, an optical fiber lens barrel 3-2 is arranged in front of a light source 3-6 on a light source module 3, an optical fiber connector 4-1 is connected with the optical fiber lens barrel 3-2, one end, far away from the optical fiber connector 4-1, of the multi-path light guide optical fiber 4-2 is connected with incident channels 1-3 on a lens mounting seat 1-1 in a plurality of detection units one by one, and the multi-path light guide optical fiber 4-2 is pressed on the lens mounting seat 1-1 by a pressing plate 1-5. Preferably, 4 detection units are arranged on the detection module 1, and the light conduction element 4 is a four-path optical fiber light guide bundle.

Further, a lens support 3-5 can be arranged between the optical fiber lens barrel 3-2 and the light source 3-6, a convex lens (not shown in the figure) can be placed on the lens support 3-5, the light source 3-6 emits light, and the light enters the optical fiber lens barrel 3-2 after being focused by the convex lens.

Referring to fig. 1, the present invention further relates to a biochemical detection apparatus, which includes a rotatable disc 2 and a detection mechanism, wherein the disc 2 is provided with a plurality of clamping positions (not shown in the figure) for clamping reagent strips; the detection mechanism comprises a multi-channel light path structure, a detection module 1 of the multi-channel light path structure is arranged below the disc 2, the position of the light source module 3 can be flexibly placed according to actual conditions, and the light conduction element 4 connects the light source module 3 with the detection module 1. When each clamping position on the disc 2 rotates to the position of the detection module 1, the information of the reagent strip clamped on the clamping position is detected.

The light sources 3-6 can adopt single wavelength or multiple wavelengths; during detection, the LED light source 3-6 emits light, enters the optical fiber lens barrel 3-2, is divided into four parts by an optical fiber coupler in the optical fiber connector 4-1, is transmitted to the incident channel 1-3 of the 4 detection units through the four light guide optical fibers 4-2, is focused by the convex lens 1-7 and then irradiates each detection hole on the bottom surface of the reagent strip, reflected light is reflected to the PD photocell 1-6 from the reflection channel 1-9, the light sensed by the PD photocell 1-6 is converted into an electric signal, and the measured light signal intensity is calculated by using a detection reflection photometry to realize the concentration detection function.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A multi-channel light path structure for dry biochemical detection is characterized by comprising a light source module, a light conduction element and a detection module, wherein one or more detection units are arranged on the detection module, each detection unit comprises an incident channel and a reflection channel, a convex lens is arranged on the incident channel, and a photocell is arranged on the reflection channel;

2. The multi-channel optical circuit structure of claim 1, wherein a side of the light source remote from the light conducting element is provided with a heat sink assembly.

3. The multi-channel optical circuit structure of claim 2, wherein the heat dissipation assembly comprises a fan and a heat dissipation fin, one side of the heat dissipation fin is connected to the fan, and the other side of the heat dissipation fin is connected to the light source.

4. The multi-channel optical circuit structure of claim 1, wherein the convex lens is provided with a sealing ring at a side of the light-transmitting member, and a gasket is provided at a side of the convex lens away from the light-transmitting member.

5. A multi-channel optical circuit structure as claimed in any one of claims 1 to 4, wherein the detection module is provided with a detection unit, and the light conducting element is an optical fiber.

6. A multi-channel optical circuit structure as claimed in any one of claims 1 to 4, wherein at least 2 detection units are provided on the detection module.

7. The multi-channel optical circuit structure according to claim 6, wherein the optical conduction element is a multi-channel optical fiber light conduction bundle, the multi-channel optical fiber light conduction bundle includes an optical fiber connector and a plurality of multi-channel optical fiber light conduction fibers connected to the optical fiber connector, an optical fiber coupler is disposed in the optical fiber connector, the number of the multi-channel optical fiber light conduction fibers corresponds to the number of the detection units one by one, the optical fiber connector is connected to the light source, and one end of the multi-channel optical fiber light conduction fiber far away from the optical fiber connector is connected to the incident channels of the plurality of detection units one by one.

8. The multi-channel optical circuit structure of claim 7, wherein the detection module is provided with 4 detection units, and the light conducting element is a four-way optical fiber light guide bundle.

9. A biochemical detection apparatus, characterized by comprising a multi-channel optical path structure according to claims 1 to 8.