CN210811068U - Improved animal catwalk gait analysis system target box - Google Patents

Improved animal catwalk gait analysis system target box Download PDF

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CN210811068U
CN210811068U CN201921288664.7U CN201921288664U CN210811068U CN 210811068 U CN210811068 U CN 210811068U CN 201921288664 U CN201921288664 U CN 201921288664U CN 210811068 U CN210811068 U CN 210811068U
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box
analysis system
gait analysis
box body
animal
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程艳彬
房敏
朱清广
孔令军
章阳阳
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of TCM
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of TCM
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Abstract

The utility model relates to the technical field of experimental apparatus, specifically disclose an improved animal catwalk gait analysis system target box, the target box includes upper box and lower box that interconnect, be equipped with the box through-hole that communicates between upper box and the lower box, be equipped with the stair structure in the lower box, the one end of stair structure is close to the box through-hole setting or is connected the setting with the box through-hole, the other end of stair structure is connected with the bottom surface of lower box; and miniature light sources are arranged inside the upper box body and the lower box body. The utility model discloses modified animal catwalk gait analysis system target case can overcome the feared psychology that the experimental animals produced because of dark and drop, guarantees that the experiment goes on smoothly.

Description

Improved animal catwalk gait analysis system target box
Technical Field
The utility model belongs to the technical field of experimental apparatus technique and specifically relates to a modified animal catwalk gait analysis system target case.
Background
Gait refers to the coordination of the components of the limbs in time and space during the movement of a human, an animal or a machine, and is an important parameter for the analysis of kinematics and behaviours. Gait analysis is a research method for analyzing the functional state of walking by means of modern computer technology and graphic image technology by utilizing the concept, method and means of biomechanics and known anatomical and physiological knowledge. The gait analysis of human body has a wide application range, such as after the nerve injury or the motor system injury of a patient, the rehabilitation or compensation can be carried out by various means, but how the effect is after the recovery is, the gait analysis of the patient is often used for evaluating. Generally, the new repair or compensation techniques must be tested or verified by animal experiments before they are used clinically, and the specific drugs for treating arthritis and other diseases must be tested by animal experiments. Therefore, the gait analysis of the animals has important practical significance, can evaluate the behavioral ability, the motor function and the cognitive ability of the animals, and has important significance for researching the mechanism, preventing and treating diseases such as neurosis, cerebral palsy, diabetes and the like. Animal gait analysis systems have become important devices for developing relevant scientific research.
Currently available CatWalk gait analysis systems (e.g., CatWalk) are commercially availableTMXT animal gait analysis system) comprises a walking platform, a power supply, a control unit, a spring lifting channel, a high-speed camera, a target box, a computer workstation and the like, wherein the target box consists of an upper part and a lower part, the upper part and the lower part are both cuboid structures, the lower part of the cuboid structure is connected with a support into a whole through a cross arm structure which is fixed on the support and extends out, the lower part of the cuboid structure is provided with a single side opening, and experimenters can put a breeding box of experimental animals in the cuboid. The cover plate surface of the lower part is provided with a circular gap, the bottom plate surface of the upper part is absent, and the upper part and the lower part are mutually connected through the circular gapEach other communicates, and lower part cuboid has a circular gap with the side that the platform is connected of walking, and inside experimental animals got into the upper portion cuboid through the breach behind the platform of walking from this to in the circular gap entering lower part cuboid was inside the raising case of placing of cuboid.
The inside of a target box of a catwalk gait analysis system used in the prior experiment is dark, and experimental animals can generate fear psychology to the inside of the target box after passing through a walking platform and are unwilling to enter. And the prior target box consists of an upper part and a lower part, a large fall exists between the upper part and the lower part, and the experimental animal is usually dare to enter the feeding box arranged in the cuboid at the lower part due to the large fall and stays in the target box at the upper part, even the experimental animal returns to the walking platform again, thereby influencing the experimental process. Therefore, aiming at the defects of the prior art, an improved animal catwalk gait analysis system target box needs to be designed and developed, so that the fear psychology of the experimental animal caused by darkness and fall is overcome, and the smooth experiment is ensured.
A search patent document, for example, patent publication No. CN101716078B, discloses a gait analysis system for small animals, comprising: and the positioning and pressure measuring device is used for acquiring the footprint and the contact pressure of the test object in real time. The method mainly realizes that the gait parameters of a test object in a slope or pure hind limb landing state are measured through a preset track, so that the problems of incomplete measurement parameters, complex measurement device and complex measurement method are solved. This patent does not relate to the modification of the target box. The invention discloses an animal model platform for studying Parkinson's disease, which mainly can more accurately reflect a behavior state judgment method of a Parkinson's disease animal model, particularly an MPTP-induced PD mouse model and evaluate the effect of a medicament or a therapy on Parkinson's disease by using the method, but the patent application does not relate to a target box for overcoming animal fear. Among the prior art, about the utility model discloses can overcome the frightening psychology that laboratory animal produced because of dark and drop to do not influence the target case of experimental result, not see the report at present.
Disclosure of Invention
The utility model aims at providing a modified animal catwalk gait analysis system target case overcomes the feared psychology that experimental animals produced because of dark and drop, guarantees to experiment and goes on smoothly
In order to achieve the purpose, the utility model adopts the technical proposal that:
an improved animal catwalk gait analysis system target box comprises an upper box body and a lower box body which are connected with each other, a communicated box body through hole is formed between the upper box body and the lower box body, a step structure is arranged in the lower box body, one end of the step structure is arranged close to or connected with the box body through hole, and the other end of the step structure is connected with the bottom surface of the lower box body; and miniature light sources are arranged inside the upper box body and the lower box body.
In the above improved target box of the animal catwalk gait analysis system, as a preferable scheme, the other end of the step structure is connected with any corner of the bottom surface of the lower box body.
In the above improved animal catwalk gait analysis system target box, as a preferred scheme, the upper box body and the lower box body are both in a cuboid structure, the lower surface of the upper box body is connected with the upper surface of the lower box body, and the long axis of the upper box body and the long axis of the lower box body form an angle of 30-60 degrees.
In the above improved animal catwalk gait analysis system target box, as a preferable scheme, the side surface of the upper box body is provided with a walking platform through hole at a position close to the walking platform of the gait analysis system.
In the above improved animal catwalk gait analysis system target box, as a preferable scheme, the miniature light source is electrically connected with a power supply and a switch of the gait analysis system through wires.
In the above improved target box of the animal catwalk gait analysis system, as a preferable scheme, a feeding box is arranged in the lower box body, and an opening of the feeding box is arranged close to the step structure.
In the above improved target box of the animal catwalk gait analysis system, as a preferable scheme, the box body through hole is arranged at a corner position far away from the walking platform through hole.
In the above improved target box of the animal catwalk gait analysis system, as a preferable scheme, the lower box body is a rectangular box body with a side surface and a single side opening.
In the above improved animal catwalk gait analysis system target box, as a preferable scheme, a movable cover plate is arranged at the position of the single-side opening, the end surface of one side of the movable cover plate is hinged with the top surface of the lower box body, and the movable cover plate can rotate around the hinged shaft.
In the prior art, the inside of a target box of the catwalk gait analysis system is dark, and experimental animals can generate fear psychology to the inside of the target box after passing through a walking platform and are unwilling to enter the target box. And the existing target box is composed of an upper part and a lower part, a large fall exists between the upper part and the lower part, experimental animals are usually dared to enter the feeding box arranged in the cuboid at the lower part due to the large fall and stay in the target box at the upper part, and the experimental animals can return to the walking platform again to influence the experimental process. The utility model discloses modified animal catwalk gait analysis system target case can overcome the feared psychology that the experimental animals produced because of dark and drop, guarantees that the experiment goes on smoothly.
Drawings
Figure 1 is the external structure schematic diagram of the target box of the animal catwalk gait analysis system of the utility model.
Figure 2 is the utility model discloses animal catwalk gait analytic system target case top view.
Figure 3 is the internal structure schematic diagram of the target box of the animal catwalk gait analysis system of the utility model.
Fig. 4 is a top view of a target box of an animal catwalk gait analysis system according to another embodiment of the invention.
Fig. 5 is an external structure diagram of a target box of the animal cathalk gait analysis system in the embodiment 2.
Fig. 6 is an external structure diagram of a target box of the animal cathalk gait analysis system in the embodiment 3.
Detailed Description
The present invention will be further described with reference to the following detailed description. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the disclosure of the present invention, and such equivalents also fall within the scope of the appended claims.
The reference numerals and components referred to in the drawings are as follows:
1. upper box body 2, lower box body 3, box body through hole
4. Step structure 5, micro light source 6, platform through hole
7. Raising box 8, single side opening 9, movable cover plate
Example 1 animal catwalk gait analysis System target Box
Please refer to fig. 1-3. Fig. 1 is the utility model discloses animal catwalk gait analysis system target case external structure schematic diagram, fig. 2 is the utility model discloses animal catwalk gait analysis system target case top view, fig. 3 is the utility model discloses animal catwalk gait analysis system target case internal structure schematic diagram.
An improved animal catwalk gait analysis system target box is used for evaluating the movement defect and gait change caused by pain of an experimental animal under the condition that the experimental animal walks naturally, and is matched with the catwalk gait analysis system for use. The target box comprises an upper box body 1 and a lower box body 2 which are connected with each other, the upper box body and the lower box body are hollow, the lower surface of the upper box body is connected with the upper surface of the lower box body, the shapes of the upper box body and the lower box body do not have special requirements, the upper box body and the lower box body are in cuboid structures, the lower box body is a rectangular box body with a side surface and a single side opening 8, and thus, an experimenter can conveniently place the feeding box of animals in the lower box body. Go up the box through-hole 3 that is equipped with the intercommunication between box and the lower box, the experimental animals that enter into in the upper box can reach the box down through this box through-hole, and then return to the animal feeding case in the box down. The shape of the box through hole has no special requirement, and for example, the box through hole can be round, square or other irregular shapes as long as the box through hole can accommodate the experimental animal to pass through and enter the lower box. Preferably, the box through-hole is provided at a corner position distant from the walking board through-hole. The lower box body is internally provided with a step structure 4 which is obliquely arranged, one end of the step structure is close to the box body through hole or is connected with the box body through hole, the other end of the step structure is connected with the bottom surface of the lower box body, and the step structure is preferably connected with any corner of the bottom surface of the lower box body. The side surface of the upper box body is provided with a walking platform through hole 6 at a position close to the walking platform of the gait analysis system, the size and the shape of the walking platform through hole have no special requirements, and the experimental animal can be accommodated into the upper box body from the walking platform. The micro light sources 5 are arranged in the upper box body and the lower box body, the micro light sources in the upper box body can be arranged on the inner surface of the box body near the through hole 6 of the walking table or near the through hole of the box body, and the micro light sources in the lower box body can be arranged on the inner surface of the box body near the step structure. The micro light source has no special requirement, as long as it can provide enough illumination for the target box, for example, the micro light source can be a micro Light Emitting Diode (LED), a common micro bulb, a micro cold cathode tube, a micro energy saving lamp tube or a micro energy saving lamp tube. The micro light source is electrically connected to the power supply and the switch to perform the illumination operation, and the operation principle is common knowledge and will not be described herein, for example, the power supply may be disposed on the inner surface of the target box, the sidewall of the target box, or the outer surface of the target box, the power switch may be disposed on the outer surface of the box body, and the micro light source may be connected in series with the power switch and the power supply to perform the operation. The power supply of the catwalk gait analysis system can be used for supplying power to the miniature light source, and after the power supply of the catwalk gait analysis system is started, the miniature light source is electrified to work, so that the additional arrangement of the power supply can be avoided.
As a preferred embodiment of this embodiment, as shown in fig. 2, the upper box and the lower box are both of a rectangular parallelepiped structure, the width of the upper box is smaller than that of the lower box, the lower surface of the upper box is connected with the upper surface of the lower box, the long axis of the upper box is parallel to that of the lower box, and the side of the upper box provided with the walking platform through hole extends to the outside of the lower box, so that the side of the upper box provided with the walking platform through hole can be placed on the catwalk gait analysis system, and the experimental animal can conveniently crawl through the walking platform through hole and enter the upper box. As another preferred embodiment of this embodiment, as shown in fig. 4, the upper box and the lower box are both of a rectangular parallelepiped structure, the width of the upper box is smaller than that of the lower box, the lower surface of the upper box is connected with the upper surface of the lower box, the long axis of the upper box and the long axis of the lower box form an angle of 30-60 degrees, and the side of the upper box provided with the walking platform through hole extends to the outside of the lower box, so that the side of the upper box provided with the walking platform through hole can be placed on the catwalk gait analysis system, and the experimental animal can conveniently crawl through the walking platform through hole and enter the upper box.
The utility model discloses a use method: the method comprises the steps of placing a lower box body on a cross arm structure extending out of a support of a catwalk gait analysis system and fixing the lower box body with the cross arm structure, aligning a walking platform through hole of an upper box body at the tail end of a walking platform of the system or putting the walking platform at the edge of the walking platform, starting a power supply to enable a micro light source to be electrified to illuminate the inside of a target box, placing a feeding box in the lower box body to enable an opening of the feeding box to face a step structure, enabling an experimental animal to enter the upper box body through the walking platform through hole in an experimental process after passing through the walking platform, enabling the experimental animal to enter the lower box body from the box body through hole in the upper box body to the other end, enabling the experimental animal to enter the lower box body in the lower part through the step structure in the lower box body, and arranging a.
In the prior art, the inside of a target box of the catwalk gait analysis system is dark, and experimental animals can generate fear psychology to the inside of the target box after passing through a walking platform and are unwilling to enter the target box. And the existing target box is composed of an upper part and a lower part, a large fall exists between the upper part and the lower part, experimental animals are usually dared to enter the feeding box arranged in the cuboid at the lower part due to the large fall and stay in the target box at the upper part, and the experimental animals can return to the walking platform again to influence the experimental process. The utility model discloses modified animal catwalk gait analysis system target case can overcome the feared psychology that the experimental animals produced because of dark and drop, guarantees that the experiment goes on smoothly.
Example 2 animal catwalk gait analysis System target Box
Referring to fig. 5, fig. 5 is a schematic external structural view of a target box of the animal cathalk gait analysis system of the embodiment. The structure of the target box of the present embodiment is substantially the same as that of embodiment 1, except that: a feeding box 7 is arranged in the lower box body, and an opening (not shown in the figure) of the feeding box faces the step structure. The size of the rearing box is suitable for the accommodating space in the lower box body, the structure of the rearing box has no special requirement as long as the rearing box is suitable for being placed in the lower box body and does not influence the experimental process, and for example, the rearing box can adopt the conventional commercially available common animal rearing box (such as a congeneric guinea pig breeding cage TK-TS-1) or the animal rearing box described in the conventional patent literature.
Example 3 animal catwalk gait analysis System target Box
Referring to fig. 6, fig. 6 is a schematic external structural view of a target box of the animal cathalk gait analysis system of the embodiment. The structure of the target box of the present embodiment is substantially the same as that of embodiment 1, except that: the single-side opening is provided with a movable cover plate 9, the size of the movable cover plate is equal to or slightly larger than that of the single-side opening, and the end surface of one side of the movable cover plate is hinged with the top surface of the lower box body, so that the movable cover plate can rotate around the hinged shaft. The effect of removable cover does not influence on the one hand and raises getting of case and put, and on the other hand can protect the experimental animal through removable cover's fender effect, avoids the experimental animal in the experimentation to fall down the injury by this single face opening from the target case, avoids influencing the experiment progress.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and additions can be made without departing from the principles of the present invention, and these improvements and additions should also be regarded as the protection scope of the present invention.

Claims (9)

1. An improved animal catwalk gait analysis system target box comprises an upper box body and a lower box body which are connected with each other, wherein a communicated box body through hole is formed between the upper box body and the lower box body; and miniature light sources are arranged inside the upper box body and the lower box body.
2. The improved animal catwalk gait analysis system target box according to claim 1, characterized in that the other end of the step structure is connected to any corner of the bottom surface of the lower box body.
3. The improved animal catwalk gait analysis system target box according to claim 1, characterized in that the upper box and the lower box are both cuboid structures, the lower surface of the upper box is connected with the upper surface of the lower box, and the long axis of the upper box and the long axis of the lower box form an angle of 30-60 degrees.
4. The improved animal catwalk gait analysis system target box according to claim 3, wherein the side of the upper box body is provided with a walking stage through hole at a position close to the walking stage of the gait analysis system.
5. The improved animal catwalk gait analysis system target box according to claim 1, wherein the miniature light source is electrically connected to the power supply and switch of the gait analysis system by wires.
6. The improved animal catwalk gait analysis system target box according to claim 1, characterized in that a feeding box is provided in the lower box body, the opening of the feeding box being located adjacent to the step structure.
7. The improved animal catwalk gait analysis system target box according to claim 4, characterized in that the box through hole is located at a corner position away from the walking platform through hole.
8. The improved animal catwalk gait analysis system target box according to claim 3, characterized in that the lower box is a rectangular box with a lateral single-sided opening.
9. The improved animal catwalk gait analysis system target box according to claim 8, characterized in that a removable cover is provided at the position of the single-side opening, the end surface of one side of the removable cover is hinged with the top surface of the lower box body, and the removable cover can rotate around the hinged shaft.
CN201921288664.7U 2019-08-09 2019-08-09 Improved animal catwalk gait analysis system target box Active CN210811068U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114176016A (en) * 2021-12-02 2022-03-15 中国科学院深圳先进技术研究院 Telescopic shading sound-proof animal behavioristics experiment box
CN114342816A (en) * 2021-12-01 2022-04-15 吉林农业大学 Device for testing analysis capability of experimental animal by using climbing ladder

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114342816A (en) * 2021-12-01 2022-04-15 吉林农业大学 Device for testing analysis capability of experimental animal by using climbing ladder
CN114176016A (en) * 2021-12-02 2022-03-15 中国科学院深圳先进技术研究院 Telescopic shading sound-proof animal behavioristics experiment box
CN114176016B (en) * 2021-12-02 2023-02-10 中国科学院深圳先进技术研究院 Telescopic shading sound-proof animal behavioristics experiment box
WO2023097760A1 (en) * 2021-12-02 2023-06-08 中国科学院深圳先进技术研究院 Animal ethology experiment box

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