CN203988056U - A kind of mice photo-thermal whipping dolorimeter - Google Patents
A kind of mice photo-thermal whipping dolorimeter Download PDFInfo
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- CN203988056U CN203988056U CN201420393092.XU CN201420393092U CN203988056U CN 203988056 U CN203988056 U CN 203988056U CN 201420393092 U CN201420393092 U CN 201420393092U CN 203988056 U CN203988056 U CN 203988056U
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Abstract
This utility model provides a kind of simple and easy mice photo-thermal whipping dolorimeter, comprises thermal source main frame, pressure regulator and control device three parts.Wherein in thermal source main frame, be provided with adjustable light sources support, light source is installed on light source bracket; The top of main frame is provided with bakelite plate, is carved with groove on bakelite plate, is provided with through hole in groove, and the center of this through hole corresponding light source, and the light source that mice sees through by the through hole on bakelite plate carries out pain sensation test; Main frame one side is provided with fan for heat radiation; Pressure regulator is used for changing output voltage and regulates the intensity of light source; The controller time relay, power control switch, timing reset switch, light control switch, by the time relay, timing, the reset etc. of whole instrument are operated, realize the semi-automation of instrument, simplify simple to operate, testing result is accurate, can in the teaching of universities and scientific research institutions or scientific experiment, promote the use of.
Description
Technical field
The invention belongs to medical animal experiment equipment, relate to a kind of mice photo-thermal whipping dolorimeter, be mainly used in Spurs pain method and detect in the experiment of the pain sensation.
Background technology
Pain is a kind of physiology and mental activity of complexity, is one of modal symptom on current clinical medicine.The body functions such as can causing shock that has an intense pain changes, and long-standing chronic pain can make patient overwhelmed with sorrow, is also usually that patient is caused a disease, disabled or lethal reason.The experiment that the pain sensation detects is everlasting in some laboratory animals and is carried out, and its cardinal principle is that laboratory animal is applied to the particular stimulation that causes pain reaction, by evaluating medicine, the impact of pain reaction is carried out to quantitatively its pain effect.The stimulating method that causes pain has a variety of; mainly be divided into physical property (heat, electricity, machinery) and the large class of chemical two; caused reaction is also different, mainly contains emissivity and shrinks back, is beneficial to posture, the powerful escape behavior (as run, jump) who stimulates and the protectiveness activity (as lick, sting, struggle) extending etc. escaped.Spurs pain method is method the most frequently used in pain sensation test experience, comprises radiant heat stimulus method, hot plate stimulus method and hot water contracting tail method etc.
Traditional simple and easy photo-thermal dolorimeter adopts the halogen lamp of 22V/250W conventionally, and light optically focused funnel on outer housing forms light beam irradiates in surveying pain position.Survey pain position and be generally 1/3 place, mouse tail rear end.Survey when pain, will survey pain position aligning lens focus, by the keying of switch, control photothermal irradiation time, the time that starts to leave to mousetail thermal source from irradiation mouse tail is recorded as TFL.Experiment starts the front basic TFL of first measuring, and by regulating heat source strength that basic TFL is controlled to 3-5 second, heat source strength adopts rheostat to regulate.Basis TFL, every continuous measurement at least 5 minutes three times, is got its meansigma methods as Basic Pain Threshold value.After drug injection, determine the time that needs the time point of record and continue record according to drug potency.For preventing scalding, TFL is no more than 10 seconds.
Traditional simple and easy photo-thermal dolorimeter stimulates and surveys the making of pain method principle according to radiant heat, although also can measure the pain reaction of animal, but there is certain defect: as unstable in the halogen bulb light source being adopted, after scioptics focus on, its visible light beam, except irradiating in surveying pain position, also has a large amount of light beams to spread to all directions; And bulb self and can not leaving in time at the heat at optically focused position after heat production; Moreover automaticity is lower, operating process step is more.These defects not only can cause the collimation error to experimenter, easily make operator divert one's attention, but also can affect the physiological status of laboratory animal, finally cause experimental result to produce larger error.
Summary of the invention
The purpose of this utility model is for problems of the prior art, and a kind of light stability, rapid heat dissipation, mice photo-thermal whipping dolorimeter that automaticity is higher are provided.
Mice photo-thermal whipping dolorimeter of the present utility model, comprises thermal source main frame, pressure regulator and controller three parts; Wherein thermal source main frame comprises housing, and light source bracket is set in housing, and light source is installed on light source bracket; One side of housing is provided with fan; The top of housing is provided with bakelite plate, is carved with groove on bakelite plate, is provided with through hole in groove, and the center of this through hole corresponding light source.The light source that mice sees through by the through hole on bakelite plate carries out pain sensation test.Input, the outfan of pressure regulator connect fan, light source by wire respectively.Can change output voltage and regulate the intensity of light source by pressure regulator.Controller comprises fixed mount and the time relay, power control switch, timing reset switch, light control switch fixed thereon, and the time relay connects the input end of pressure regulator by wire.Power control switch, timing reset switch, light control switch respectively control instrument main power unlatching or close the timing of the time relay or reset, and in main frame, light source and fan are opened simultaneously or close; The Circuits System of the whole device of time relay control, to realize the semi-automation of instrument.
In order to make the position of light source adjustable, light source bracket comprises the longitudinal carrier that is fixed on housing medial wall and by nut horizontal support mounted thereto, light source is arranged on horizontal support.Horizontal support can regulate by nut on longitudinal carrier.
Described time relay band digital display screen, so that timing.
Described light source is 8V/50W halogen lamp, makes light source under lower-wattage, just can produce high current, and light is dark, self light-gathering is good, can farthest reduce the interference to experimenter and laboratory animal.
Fan is selected DC/AC mute fan, in realizing heat radiation, can reduce the interference to experimenter and laboratory animal as far as possible.
The relative prior art of this utility model has the following advantages:
1, survey pain principle design according to radiant heat stimulus method and make, its light source stability is good, the good heat dissipation effect of thermal source parts;
2, the position of light source and intensity are adjustable, test adapting under different condition;
3, adopt the time relay to carry out the operation such as timing, reset and circuit control of whole instrument, realize instrument semi-automation, simplified simple to operately, testing result is accurate, can in the teaching of universities and scientific research institutions or scientific experiment, promote the use of.
Brief description of the drawings
Fig. 1 is the main structure chart of this utility model mice photo-thermal whipping dolorimeter.
Fig. 2 is the structure chart of Fig. 1 medium-height trestle 1 and support 2.
Fig. 3 is this utility model photo-thermal whipping dolorimeter circuit structure diagram.
Detailed description of the invention
Below in conjunction with accompanying drawing, structure and the work process of this utility model photo-thermal whipping dolorimeter are described further.
With reference to Fig. 1, a kind of mice photo-thermal whipping dolorimeter, comprises thermal source main frame 1, pressure regulator 7 and 8 three parts of controller.Wherein thermal source main frame comprises housing (the square housing of the 20cm × 20cm × 20cm making for rustless steel), light source bracket is set in housing, this light source bracket comprises the longitudinal carrier 3 being fixed on housing medial wall and fixedly mounts horizontal support 4 thereon by nut, and the height of horizontal support 4 can regulate by nut; Light source 5. light source 5 choice for use 8V/50W halogen lamp are installed, for thermal source main frame provides light and heat on horizontal support 4.One side of housing is provided with the fan DC/AC mute fan 6 that power is 220W, for the heat radiation of whole host apparatus.The top of housing is provided with bakelite plate 2, is carved with groove on bakelite plate, is provided with through hole in groove, and the center of this through hole corresponding light source 5.The light source that mice sees through by bakelite plate small through hole carries out pain sensation test.
Pressure regulator 7 adopts common pressure regulator, and its input, outfan connect fan 6, light source 5 by wire respectively.
Controller 8 comprises fixed mount (for the stainless steel frame of 16cm × 16cm × 8cm) and the time relay 12, power control switch 9, timing reset switch 10, light control switch 11 fixed thereon, and the time relay 12 connects the input end of pressure regulator 7 by wire.Power control switch 9 is controlled the unlatching of main power or is closed; The 10 control time timing of timing reset switch or reset; Light control switch 11 controls light source and fan opens simultaneously or cuts out; The time relay 12 is with digital display screen, can be used for timing, and can control by it Circuits System of whole instrument.The time relay 12 is containing eight joints, and 4. wherein 2. 7. control circuit main power, 1. control timing, 1. 3. controls timing and reset, and 5. 8. controls light source (with reference to Fig. 3).Power control switch 9 upper lefts are connected attaching plug 13 with upper right, left connection 2., right connection 7., control the opening and closing of main power.Timing reset switch 10 lower-lefts connect 1., left connection 3., control reset and timing.The left connection of light control switch 11 1., 4. upper left connect, timing when connection.The right connection pressure regulator input interface of light control switch 11 one end, 5. bottom right connects, the input interface other end connects pressure regulator plug 14 one end simultaneously, 8. the pressure regulator plug other end connects, and pressure regulator input interface connects fan, output interface connects light source, jointly regulates the opening and closing of light source and fan.
Claims (5)
1. a mice photo-thermal whipping dolorimeter, is characterized in that: comprise thermal source main frame (1), pressure regulator (7) and controller (8) three parts; Wherein thermal source main frame comprises housing, and light source bracket is set in housing, and light source (5) is installed on light source bracket; One side of housing is provided with fan (6); The top of housing is provided with bakelite plate (2), is carved with groove on bakelite plate, is provided with through hole in groove, and the center of this through hole corresponding light source (5); Input, the outfan of pressure regulator (7) connect fan (6), light source (5) by wire respectively; Controller (8) comprises fixed mount and the time relay (12), power control switch (9), timing reset switch (10), light control switch (11) fixed thereon, and the time relay (12) connects the input end of pressure regulator (7) by wire.
2. mice photo-thermal whipping dolorimeter as claimed in claim 1, it is characterized in that: described light source bracket comprises the longitudinal carrier (3) that is fixed on housing medial wall and by nut horizontal support (4) mounted thereto, light source (5) is arranged on horizontal support (4).
3. mice photo-thermal whipping dolorimeter as claimed in claim 1, is characterized in that: described time relay band digital display screen.
4. mice photo-thermal whipping dolorimeter as claimed in claim 1, is characterized in that: described light source is 8V/50W halogen lamp.
5. mice photo-thermal whipping dolorimeter as claimed in claim 1, is characterized in that: fan is DC/AC mute fan.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420393092.XU CN203988056U (en) | 2014-07-16 | 2014-07-16 | A kind of mice photo-thermal whipping dolorimeter |
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| CN201420393092.XU CN203988056U (en) | 2014-07-16 | 2014-07-16 | A kind of mice photo-thermal whipping dolorimeter |
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| CN203988056U true CN203988056U (en) | 2014-12-10 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198593A (en) * | 2017-06-30 | 2017-09-26 | 中国人民解放军第四军医大学 | A kind of universal temperature-sensitive stimulation instrument |
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2014
- 2014-07-16 CN CN201420393092.XU patent/CN203988056U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198593A (en) * | 2017-06-30 | 2017-09-26 | 中国人民解放军第四军医大学 | A kind of universal temperature-sensitive stimulation instrument |
| CN107198593B (en) * | 2017-06-30 | 2023-08-04 | 中国人民解放军第四军医大学 | Universal thermosensitive stimulator |
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