CN205943069U - Wireless infrared remote control light heredity system - Google Patents
Wireless infrared remote control light heredity system Download PDFInfo
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- CN205943069U CN205943069U CN201620890541.0U CN201620890541U CN205943069U CN 205943069 U CN205943069 U CN 205943069U CN 201620890541 U CN201620890541 U CN 201620890541U CN 205943069 U CN205943069 U CN 205943069U
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Abstract
The utility model discloses a wireless infrared remote control light heredity system. Power supply drive plate, infrared transmitting tubes lamp area, signal source and 5V power are drawn together to the infrared emission hand ladle, infrared receiving terminal includes infrared receiving tube, 3.7V lithium cell, comparison circuit and blue light -emitting diode. Utilize bright the going out in signal source control power supply drive plate's on -off control infrared transmitting tubes lamp area for the same basically and synchronous bright the going out of luminance in infrared transmitting tubes lamp area, infrared receiving tube receives infrared transmitting tubes lamp area infrared transmitting tubes's infrared signal, goes out through comparison circuit control the bright of blue infrared diode, and blue light -emitting diode's light signal passes through the leading -in organism intracellular of optic fibre, realizes effectual photostimulation. The utility model discloses can realize remote wireless control in the experimental box, it is small, high integration, compact structure accurately and timely responds to the remote control signal of signal source, and the infrared remote control scope is big, can not influence the free activity of mouse in on a large scale, is favorable to carrying on the experiment of large -scale behaviouristics.
Description
Technical field
This utility model is related to the method and system of light genetic technique photostimulation, has especially related to a kind of Radio infrared distant
Control light genetic system.
Background technology
Light hereditism (optogenetics) technology, is a kind of by accurately controlling with reference to optical technology and genetics technology
The method of cellular activity processed, using light genetics technology, Neuroscience Research person deep enough can probe into each god in a core group
Through the position between unit and relation, understand inherent interaction between multiple cores groups, thus to brain structure and nervous system
Conformation function has apparent understanding.Except carry out basis neuronal structure research it is often more important that, using this complete equipment
With some animal disease models, can probe under condition of living body, common nervous system disease such as parkinsonism, Alzheimer
The brain pathological change of disease, depression etc., understand in it neuron pathological change, and understand its therapeutic effect, be last solution
Certainly clinical nervous system disease provides multi-faceted therapeutic strategy.And can be used for treatment clinically, it is applied to retina
With the blind patient of pathological changes, patient is allowed to see light again.
Light genetics technology has just become the study hotspot of department of neurology educational circles once releasing, and is extensively used by each laboratory at once
In the research of various brain sciences.Through development in a few years, light hereditism achieves to neuron in cellular resolution level
Manipulation, thus having walked out the first step for realizing neural microdissection.And the light heredity device production market for home and abroad, all
Even it is in the starting stage.
The device of light heredity at present mostly is non-wireless means, stimulates light using fiber-optic transfer or requires mouse head to fix and nothing
Line apparatus volume is bigger than normal, quality lays particular stress on the freely activity that all can be restricted to mice, thus cannot be distinguished from is due to Photic Stimulation
Or the restriction due to equipment produces impact for the behavior of mice, leverages the science of experiment.In addition, wirelessly
Many complexity and the costs also increasing system using wireless charging of power supply mode, make the biological experiment cannot be common
Carry out in biological behavioristics experimental box.
Utility model content
In order to solve the problems, such as in background technology, the purpose of this utility model there are provided a kind of Radio infrared remote control light
Genetic system.
The technical solution adopted in the utility model is：
This utility model includes infrared emission end and infrared receiver end, passes through between infrared emission end and infrared receiver end
The mode of infrared remote control controls the light on and off of the optical signal in infrared receiver end, and it is thin in vivo that optical signal is imported biology by optical fiber
Intracellular, realizes effective photostimulation.
Described infrared emission end includes power drives plate, infrared transmitting tube light bar, signal source and the 5V for power supply
Power supply, power driving circuit is connected with infrared transmitting tube light bar and signal source respectively, 5V power supply respectively with power driving circuit, letter
Number source connects and is powered；
Described infrared receiver end includes infrared receiving tube, 3.7V lithium battery, comparison circuit and blue LED, than
Be connected with infrared receiving tube and blue LED respectively compared with circuit, 3.7V lithium battery respectively with comparison circuit and infrared connect
Closed tube connects.Comparison circuit of the present utility model and the equal designed, designed of power driving circuit.
Control the break-make of power driving circuit using signal source, thus controlling the light on and off of infrared transmitting tube light bar, no matter outward
The change of boundary's temperature it is ensured that the constant current of the total branch road of light bar, and due to the C-V characteristic of infrared transmitting tube is basically identical can
So that the essentially identical and synchronous light on and off of the luminous power of each infrared transmitting tube, infrared receiving tube receives the infrared of infrared transmitting tube
Signal, controls the light on and off of blue infrared diode through comparison circuit, and the optical signal of blue LED imports life by optical fiber
In object inner cell, realize effective photostimulation.
Described infrared transmitting tube light bar is arranged on annular one circle of the peripheral side wall of disposed casing.
Preferably, described infrared transmitting tube light bar wherein is arranged in the case being located apart from top surface 1/4 box height
Make a circle in body sidewall week position, and another is arranged in the position that makes a circle in wall box week being located apart from bottom surface 1/4 box height.
Described power driving circuit includes chip U1, and the DIM end of chip U1 2 feet through resistance R1 and socket JIN1 are even
Connect, the VIN end of chip U1 is connected with 1 foot of socket JIN1 through electric capacity C4 and electric capacity C5 respectively, the VIN end of chip U1 is direct and slotting
3 feet of mouth JIN1 connect, and the GND end of chip U1 is directly connected with 1 foot of socket JIN1, and the SW end of chip U1 through inductance L1 and is inserted
3 feet of mouthful JIN1 connect, and the SW end of chip U1 is connected with 1 foot of socket JIN1 through electric capacity C1 and inductance L2, electric capacity C2 and electric capacity
It is connected on the two ends of inductance L2 after C3 parallel connection with diode D1, after diode Dz1, resistance R2 and resistance R3 series connection, be connected to electric capacity
The two ends of C2, the FB end of chip U1 is connected between diode Dz1 and resistance R2, exit between diode Dz1 and electric capacity C2
Mouth connects the positive pole of described infrared transmitting tube light bar, draws port and connect described infrared emission spot between resistance R2 and resistance R3
The negative pole of band.
Described infrared transmitting tube light bar is to form each group lamp bead group by the series connection of multiple lamp bead, more in parallel by each group lamp bead group
Form light bar.In the branch road of each lamp bead, the small resistor of one 1 Ω -2 Ω of series connection is with balanced balanced current.
The comparison circuit that the first is implemented includes voltage comparator piece U2, and the negative input end of chip U2 connects NPN triode
Between the colelctor electrode of Q1 and resistance R5, the resistance R5 other end is directly connected with power supply VCC, the ground level warp successively of NPN triode Q1
It is connected with power supply VCC after infrared receiving tube D2 and resistance R4, the emitting stage of NPN triode Q1 is grounded GND, chip U2 through resistance R9
Positive input terminal be connected between resistance R6 and resistance R8, the other end of resistance R6 and resistance R8 be connected respectively to power supply VCC and
Ground GND, positive feedback resistor Rf1 two ends are connected directly between positive input terminal and the outfan of chip U2 respectively, and resistance R7 series connection is blue
In parallel with pull-up resistor RL1 after LED1, blue led 1 is described blue LED, and the two ends of pull-up resistor RL1 are respectively
It is connected with chip U2 outfan and power supply VCC, the VCC end of chip is connected with power supply VCC and ground GND respectively with GND end.
The comparison circuit that second is implemented includes voltage comparator chip U3, resistance R10 and infrared receiving tube D3 series connection even
It is connected between power supply VCC and ground GND, resistance R11 and resistance R13 is connected in series between power supply VCC and ground GND, chip U3's
Positive input terminal is connected to resistance R19 and the centre of infrared receiving tube D3, and negative input end is connected in the middle of resistance R11 and resistance R13,
Electric capacity CP1 is connected between positive input terminal and the negative input end of voltage comparator U3, and the outfan of voltage comparator U3 is through resistance
R12 and infrared transmitting tube LED2 connect, the other end ground connection of LED2, the VCC end of voltage comparator U3 and GND end respectively with power supply
VCC is connected with ground GND.
Apart from farther, the circuit design of second embodiment is compacter and little for the infrared remote control of wherein the first embodiment
Type.
The power driving circuit at this utility model infrared emission end can ensure that the brightness of the infrared transmitting tube in light bar is basic
Identical and stable, the design of light bar ensures that mice activity in the range of biological behavioristics experimental box can receive infrared remote control
Signal.Receiving terminal can guarantee that blue LED can respond in time and accurately when receiving infrared remote-controlled signal, and
Light intensity is unrelated with remote control distance and does not receive and does not work completely during signal.
This utility model is powered to the driving plate of transmitting terminal using 5V power supply, and electricity driving plate being exported using signal source
Pressure signal is controlled, thus each infrared transmitting tube synchronizes control in the latter linked light bar to driving plate.By red
The transmission of outer infrared signal between pipe, the final dutycycle of receiving terminal blue led light on and off controlling 3.7V lithium battery power supply and frequency
The characteristics such as rate.
The beneficial effects of the utility model are：
This utility model system may be implemented in remote-wireless manipulation in experimental box, mice activity is not formed and limits, makes
It can move freely in relatively large scope, thus can carry out large-scale Behaviors survey.If can in conjunction with electrophysiological recording instrument
With the effect of stimulation of real time record feedback, record the physiological activity of neuron while stimulation, thus probing into the function of neuron.
Compared to prior art, receiving terminal small volume of the present utility model, highly integrated, compact conformation, for signal source
Remote signal accurately and timely respond, infrared remote control scope is big, does not interfere with mice in freely activity interior on a large scale, favorably
In carrying out large-scale Behaviors survey.
Brief description
Fig. 1 is the theory diagram of this utility model system.
Fig. 2 be 50cm × 50cm × 25cm biological behavioristics experimental box in light bar arrangement schematic diagram.
Fig. 3 is the corresponding physical circuit schematic diagram of Fig. 1 infrared emission end power drives plate.
Fig. 4 is a kind of physical circuit schematic diagram of embodiment in Fig. 1 infrared receiver end.
Fig. 5 is the physical circuit schematic diagram of Fig. 1 infrared receiver end another kind embodiment.
Specific embodiment
Below with reference to the accompanying drawings with reference to specific embodiment, this utility model is further described.
This utility model embodiment is as follows：
This utility model adopts the lithium battery power supply of the 0.4cm3 of 3.7V, infrared wireless remote control, and circuit-board laying-out is compact.Tool
Body implement in all elements realized with relatively low product price and product complexity can controlled in wireless accurate light genetic technique
Function.
Wherein, specific implementation process is, 5V is powered and directly supplied using USB Power Adapter, does not separately put voltage and turns
Change circuit, and the power supply respectively as signal source and power drives plate.Signal source depends on the circumstances, and directly adopts DDS in this example
Signal source, then can save circuit board, direct wiring, and setting control signal is amplitude 5V, frequency 30HZ, dutycycle 30%, biasing
100% pwm signal.Connect power drives plate, wherein the 3 of power drives plate mouthful connecting signal source is to control break-make (high level
Low level), 2 mouthfuls connect 5V power supply, and 1 mouthful is earth terminal.
On power drives plate, the position that two big pads of setting access as light bar.Power drives plate controls thereafter red
Emission spot band light on and off simultaneously and brightness is essentially identical.Because, in infrared transmission, the angle of divergence of infrared emission is little, transmission range
Short restriction, so need light bar to design to ensure can receive infrared signal in the range of biological behavioristics experimental box.
As illustrated in Fig. 2, according to the requirement of biological behavioristics experimental box size, respectively at upper (thick dashed line) and downside (fine dotted line)
Two light bar of setting, a power drives strip carries a light bar, and each light bar band carries the individual little electricity parallel with one another in 28 (7 × 4)
Road plate, infrared transmitting tubes of 6 series connection of each little welding circuit board, the small resistor of 1 Ω -2 Ω that connects in each branch road with
Balanced balanced current.Through infrared signal transmission, infrared receiving tube receives optical signal, is converted into the signal of telecommunication, sentences through comparison circuit
Break and have been received by signal, export high level, drive blue LED to light.Thus ensureing infrared distant by remote-wireless
It is 30Hz that the mode of control utilizes signal source to control the frequency of blue LED flicker, dutycycle 30%.
Couple 593nm blue light using optical fiber, by the optical fiber of implantation, illuminated positioned at brain Semen Armeniacae Amarum core region with blue light
Specific neural circuit, acts on photaesthesia channel C hR2 (Channelrhodopsin-2), opens ion channel, generation action electricity
Position.Corpus amygdaloideum is the core position tackling the basic emotions such as frightened, invasion in brain, is also the portion that rodent controls anxiety
Point.Carry out Behaviors survey, the original mice moving back to corner because frightened can be observed and start to explore the environment of surrounding.Simultaneously
Carry out electro physiology extracellular recording, also provable equipment effectively exports photostimulation.Carry out Y labyrinth using C57 labelling mice simultaneously
Behaviors survey, verifies illumination successful activation VTA-DA neuron, opens award path.
The power drives plate circuit design cardinal principle at infrared emission end is the SEPIC copped wave DC-DC with current feedback
Changer.Kernel control chip adopts the LM3410X of TI company, is voltage reference foot according to FB foot, for LM3410X chip,
190mV can be clamped the voltage at, then output total current can be controlled by feedback resistance R2, realizes constant current output.Select is infrared
The performance of transmitting tube is essentially identical, can with basic guarantee each series connection lamp bead branch current constant as 20mA, then every in light bar
The brightness of lamp bead is essentially identical；This circuit can allow for output voltage and is more than, is less than or equal to input voltage, because chip turns off
In the case of, under the isolation of electric capacity, output voltage is down to 0V completely, that is, output be not required to extra control parts can completely
Turn off, therefore the light on and off for transmitting light bar control the Enable Pin fully relying on conversion chip to control its soft start.
In circuit theory diagrams Fig. 3,1,2,3 port is drawn and is done panel, and wherein 3 mouthfuls connecting signal sources are to control break-make
(high level low level), 2 mouthfuls connect 5V power supply, and 1 mouthful is earth terminal；R1, in order to current limliting, prevents source current excessive damage chip；
, in order to energy storage, after switching off, the energy of C1 storage can make light bar both end voltage be more than electricity to L2 transfer for C4, C5, L1, C1, L2
Source voltage；Schottky diode D1 has switching frequency height and the low advantage of forward voltage drop, as high-frequency rectification；Zener diode
Dz1 is connected in parallel on light bar two ends with R2 with overcurrent protection after connecting；R3 controls the total current flowing through light bar；C2 and C3 is connected in parallel on electricity
Source two ends, the big electrochemical capacitor of one of electric capacity is in order to filter the low frequency component of power supply, the little ceramic electrical of another one electric capacity
Hold in order to eliminate the inductance characteristic that bulky capacitor produces in high frequency, eliminate drain capacitance.This circuit design load capacity will allow defeated
Enter the electric current that end produces maximum 2A, and outfan can produce the up to voltage of 24V it is contemplated that the average pressure drop of every lamp bead exists
1.3V about, and connecting lamp bead matrix by the way of series-parallel connection, the conservative efficiency factor according to 0.6 estimates, every plate can drive
GL100MN lamp bead load up to 216, fully sufficient using and further debug in use more powerful transmitting instead
Pipe.And through the compression of rational placement-and-routing, current plank size controls：24.8×29.8×0.8mm.In power drives plate
On, the position that light bar accesses is two big pads, then only need to make compatible pad and directly driving when designing light bar
Mount on plate.
The infrared receiver end of the first embodiment, such as Fig. 4, using the most frequently used voltage comparator LM393 it is ensured that not
Receive during infrared signal that LED1 keeps not working and the distance between brightness and infrared tube are unrelated, and it is electric to add audion to amplify
Stream is thus amplify the excursion of output voltage signal.R4 is in order to the current limliting of infrared receiving tube；Current signal is converted into electricity by R5
Pressure signal inputs as negative voltage；R6 and R8 determines reference voltage；Rf1, as positive feedback resistance, constitutes hysteresis circuitry, mesh
Be in order that comparator work more stable；RL1 is to push away to exempt from pull-up resistor；R7 series LED 1 adopts common anode connection, then only have
Current-limiting resistance R7 partial pressure, reduces the power consumption on pull-up resistor RL1, and can control LED by the direct current-limiting resistance that adjusts
Brightness；JPWR1, as the two ends of power supply, is parallel with electric capacity C6, electric capacity C7 and electric capacity C8, processes for power filter.
The infrared receiver end of second embodiment, such as Fig. 4, are provided without the electric current that audion amplifies infrared receiving tube output
Signal, leads to the response range of infrared tube to reduce, but the size of receiver board can significantly reduce.Wherein, R10 is used for sensing electricity
Stream sampling；R11 and R13 common threshold value voltage；Cp1 filters for input signal, is used for filtering High-frequency Interference；C9 is used for power supply
Filtering；R12 is used for LED2 current limliting.Compared with embodiment one, some experiment redundancy branch roads original all remove, LED2
It is changed to common cathode type of drive.
In being embodied as, the TLV3691 super low-power consumption recommending output mode ratio that comparator is produced using Texas Instrument (TI) company
Compared with device, built-in hysteresis link, the lagging feedback of outside can be omitted, reduce circuit board volume further.Sensor and transmitting tube
Infrared tube PT100MF and GL100MN being produced using Sharp (SHARP) company.Due to being that the regular manufacturer of famous brand produces, should
Two kinds of elements can find reliable data book, provides accurate theoretical foundation for design.Additionally, the rwo is joined for manufacturer
To infrared tube, both transmitting and receive frequency spectrum on just can match well, electricity conversion can reach 95%
More than.And its transmitting tube GL100MN small volume while there is certain power, can be very flexible when arranging array；
Simultaneously reception pipe PT100MF dark current low (<100nA), the big (saturation of out-put dynamic range>10mA), sensitivity is high and volume
Compact, volume can be reduced further for receptor.The size of receptor can accomplish 9.8mm × 7.5mm × 0.8mm at present.
Thus, this utility model can achieve that in light bar, infrared transmitting tube both end voltage is consistent, in 50cm × 50cm × 25cm
Biological behavioristics proof box in, all standing of infrared remote-controlled signal distribution, and there is not the jitter phenomenon of signal；Receiving terminal can
To ensure 593nm blue LED light power stability.Finally realize signal source for spies such as the dutycycle of 593nm blue led, frequencies
The precise control of property is thus obtain effective optical stimulus signal.
This utility model has the outstanding advantages such as big, the headset equipment small volume of remote range it is adaptable to light genetic system,
A series of biological experiment researchs can be carried out, such as Photic Stimulation, in ChR2, produces action potential；Probe into whether illumination successfully swashs
VTA-DA neuron alive, opens award path etc..
Claims (6)
1. a kind of Radio infrared remote control light genetic system it is characterised in that：Including infrared emission end and infrared receiver end, infrared
Control the light on and off of the optical signal in infrared receiver end by way of infrared remote control between transmitting terminal and infrared receiver end；
Described infrared emission end includes power drives plate, infrared transmitting tube light bar, signal source and the 5V power supply for power supply,
Power drives plate is connected with infrared transmitting tube light bar and signal source respectively；
Described infrared receiver end includes infrared receiving tube, 3.7V lithium battery, comparison circuit and blue LED, relatively more electric
Road is connected with infrared receiving tube and blue LED respectively；
Control the break-make of power driving circuit using signal source, thus controlling the light on and off of infrared transmitting tube light bar, infrared receiving tube
Receive the infrared signal of infrared transmitting tube light bar infrared tube, control the light on and off of blue LED through comparison circuit.
2. a kind of Radio infrared remote control light genetic system according to claim 1 it is characterised in that：Described infrared emission
Spot band is arranged on annular one circle of the peripheral side wall of disposed casing.
3. a kind of Radio infrared remote control light genetic system according to claim 1 it is characterised in that：Described power drives
Circuit includes chip U1, and the DIM end of chip U1 is connected with 2 feet of socket JIN1 through resistance R1, and the VIN end of chip U1 is respectively through electricity
Hold C4 and electric capacity C5 to be connected with 1 foot of socket JIN1, the VIN end of chip U1 is directly connected with 3 feet of socket JIN1, chip U1's
GND end is directly connected with 1 foot of socket JIN1, and the SW end of chip U1 is connected with 3 feet of socket JIN1 through inductance L1, chip U1's
SW end is connected with 1 foot of socket JIN1 through electric capacity C1 and inductance L2, is connected on diode D1 after electric capacity C2 and electric capacity C3 parallel connection
It is connected to the two ends of electric capacity C2, the FB end of chip U1 is even after the two ends of inductance L2, diode Dz1, resistance R2 and resistance R3 series connection
It is connected between diode Dz1 and resistance R2, draw port between diode Dz1 and electric capacity C2 and connect described infrared transmitting tube light bar
Positive pole, between resistance R2 and resistance R3 draw port connect described infrared transmitting tube light bar negative pole.
4. a kind of Radio infrared remote control light genetic system according to claim 1 it is characterised in that：Described infrared emission
Spot band is to form each group lamp bead group by the series connection of multiple lamp bead, then forms light bar by the parallel connection of each group lamp bead group.
5. a kind of Radio infrared remote control light genetic system according to claim 1 it is characterised in that：Described comparison circuit
Including voltage comparator piece U2, the negative input end of chip U2 connects between colelctor electrode and the resistance R5 of NPN triode Q1, resistance R5
The other end is directly connected with power supply VCC, the ground level of NPN triode Q1 successively after infrared receiving tube D2 and resistance R4 with power supply
VCC connects, and the emitting stage of NPN triode Q1 is grounded GND through resistance R9, and the positive input terminal of chip U2 is connected to resistance R6 and resistance
Between R8, the other end of resistance R6 and resistance R8 is connected respectively to power supply VCC and ground GND, and positive feedback resistor Rf1 two ends are straight respectively
It is connected on positive input terminal and the outfan of chip U2 in succession, in parallel with pull-up resistor RL1 after resistance R7 series connection blue led 1, pull-up electricity
The two ends of resistance RL1 are connected with chip U2 outfan and power supply VCC respectively, the VCC end of chip and GND end respectively with power supply VCC
It is connected with ground GND.
6. a kind of Radio infrared remote control light genetic system according to claim 1 it is characterised in that：
Described comparison circuit includes voltage comparator chip U3, and resistance R10 and infrared receiving tube D3 are connected in series in power supply VCC
And ground GND between, resistance R11 and resistance R13 is connected in series between power supply VCC and ground GND, and the positive input terminal of chip U3 connects
In the centre of resistance R19 and infrared receiving tube D3, negative input end is connected in the middle of resistance R11 and resistance R13, and electric capacity CP1 connects
Between the positive input terminal and negative input end of voltage comparator U3, the outfan of voltage comparator U3 is through resistance R12 and infrared
Penetrate pipe LED2 to connect, the other end ground connection of LED2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620890541.0U CN205943069U (en) | 2016-08-16 | 2016-08-16 | Wireless infrared remote control light heredity system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620890541.0U CN205943069U (en) | 2016-08-16 | 2016-08-16 | Wireless infrared remote control light heredity system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109410558A (en) * | 2018-06-20 | 2019-03-01 | 深圳市宏芯达科技有限公司 | A kind of infrared code Intelligent Compression chip |
| CN112133079A (en) * | 2019-06-25 | 2020-12-25 | 深圳拓邦股份有限公司 | Infrared detection circuit and method |
-
2016
- 2016-08-16 CN CN201620890541.0U patent/CN205943069U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109410558A (en) * | 2018-06-20 | 2019-03-01 | 深圳市宏芯达科技有限公司 | A kind of infrared code Intelligent Compression chip |
| CN109410558B (en) * | 2018-06-20 | 2023-12-12 | 深圳市宏芯达科技有限公司 | Intelligent compression chip for infrared codes |
| CN112133079A (en) * | 2019-06-25 | 2020-12-25 | 深圳拓邦股份有限公司 | Infrared detection circuit and method |
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