CN210113275U - Anti-pollution nucleic acid extraction system - Google Patents
Anti-pollution nucleic acid extraction system Download PDFInfo
- Publication number
- CN210113275U CN210113275U CN201920626202.5U CN201920626202U CN210113275U CN 210113275 U CN210113275 U CN 210113275U CN 201920626202 U CN201920626202 U CN 201920626202U CN 210113275 U CN210113275 U CN 210113275U
- Authority
- CN
- China
- Prior art keywords
- station
- nucleic acid
- acid extraction
- base
- stirring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model aims at providing an anti-pollution nucleic acid extraction system, including a base, set up shell body on the base, set up the station unit inside the shell body, set up the unit of drawing that is used for nucleic acid to draw in station unit top, the station unit includes a station platform, and the station bench is provided with the station that is used for laying reagent container, and the station platform is equipped with a plurality of inlet ports at station department fretwork, shell body upper portion, is equipped with a plurality of ventholes on the base, and venthole department is equipped with the negative pressure source. The utility model discloses construct a negative pressure system according to the structure of nucleic acid extraction appearance to form a top-down's air current to pressure differential, waste liquid waste gas in the nucleic acid extraction appearance is discharged along air current to pressure differential direction, makes the waste liquid waste gas that produces in the nucleic acid extraction process can discharge downwards in time, avoids waste liquid waste gas and the sample in the reagent container to mix and causes the pollution, and can reduce the sample that causes because of the air flow and volatilize.
Description
Technical Field
The utility model relates to an anti-pollution nucleic acid extraction system.
Background
The nucleic acid extraction instrument is a device commonly used in laboratories and hospitals, generally comprises a closed space enclosed by a shell, wherein the closed space is internally provided with nucleic acid extraction equipment, and when the nucleic acid extraction equipment works, the closed space is closed. Because the liquid reagent is often needed to be used when extracting nucleic acid, and the liquid reagent is often easy to volatilize, after the nucleic acid extraction equipment works for a period of time, the volatilized reagent is collected in a closed space, so that when the nucleic acid extraction is finished and the nucleic acid extractor is opened, the gaseous reagent can be leaked into the atmosphere to cause air pollution, and the gaseous reagent left in the nucleic acid extractor can cause pollution to the reagent extracting nucleic acid next time. In addition, when nucleic acid is extracted, different reagents are volatilized and then are in a closed space together, so that chemical reaction is easily caused between the reagents, and the reagents extracting nucleic acid are further polluted.
SUMMERY OF THE UTILITY MODEL
For overcoming the defects of the prior art, the embodiment of the utility model provides an anti-pollution nucleic acid extraction system, it constructs a negative pressure system according to the structure of nucleic acid extraction appearance to form a top-down's air current to pressure differential, waste liquid waste gas in the nucleic acid extraction appearance is discharged along air current to pressure differential direction, make the waste liquid waste gas that produces in the nucleic acid extraction process can in time discharge downwards, avoid waste liquid waste gas and the sample mixture among the reagent container to cause the pollution, and can reduce the sample that causes because of the air flow and volatilize.
In order to achieve the aim, the anti-pollution nucleic acid extraction system comprises a base, a shell arranged on the base, a station unit arranged inside the shell, and an extraction unit arranged above the station unit and used for extracting nucleic acid, wherein the station unit comprises a station platform, the station platform is provided with a station for placing a reagent container, the station platform is hollow at the station, the upper part of the shell is provided with a plurality of air inlets, the base is provided with a plurality of air outlets, and the air outlets are provided with negative pressure sources.
Preferably, there are 4 ventholes, set up 4 corners at the base respectively.
Preferably, the negative pressure source is a negative pressure electric fan.
Preferably, the lower side of the station table is provided with a separation plate, the base is provided with a support frame for supporting the separation plate, and the separation plate is provided with a vent hole at a position corresponding to the station at the upper side of the negative pressure source.
Preferably, the vent holes are honeycomb holes.
Preferably, the extraction unit comprises a frame, a stirring device and a magnetic attraction device which are arranged on the frame, and an up-and-down driving device for driving the stirring device and the magnetic attraction device to move up and down.
Preferably, agitating unit includes the stirring frame, sets up the stirring consumptive material on the stirring frame, inhale the magnetism device and include the magnetic frame, set up the magnetic rod on the magnetic frame, the stirring consumptive material includes a plurality of stirring rods that correspond with the reagent container, the stirring rod axle center is provided with the ascending magnetism blind hole of inhaling of opening, the magnetic rod can be inserted and inhale the magnetism blind hole, drive arrangement inhales the magnetism drive arrangement of the up-and-down motion of stirring frame and drive magnetic frame from top to bottom including the stirring drive arrangement of drive stirring frame up-and-down motion.
Preferably, the station unit further comprises a rotating assembly, the station table can rotate around the rotating assembly, and the rack is fixedly arranged on the rotating assembly.
Preferably, the rotating assembly comprises a rotating base fixedly arranged on the base, a station seat rotatably arranged on the rotating base and a rack seat used for installing the rack, a transmission part in transmission connection with the rotary driving device is arranged at the lower end of the station seat, the station platform is arranged at the upper end of the station seat, and the rack seat is fixedly connected with the rotating base.
Preferably, a boss used for limiting and bearing is arranged on the rotary base, the station seat is arranged on the boss, the lower side of the rack seat is a connecting portion, the upper side of the rack seat is an installation portion, a limiting portion used for limiting the upper side of the station seat is arranged between the connecting portion and the installation portion, the rack is installed on the installation portion, and the connecting portion is fixedly connected with the rotary base after penetrating through the station seat.
Compared with the prior art, the utility model the advantage do:
the venthole and the negative pressure source of anti-pollution system set up on the base, can form a top-down air flow inside the nucleic acid extraction appearance when anti-pollution system starts for waste liquid waste gas that the nucleic acid extraction in-process produced can in time be got rid of downwards, avoids waste liquid waste gas and the sample in the reagent container to mix and causes the pollution, and can reduce the sample that causes because of the air flow and volatilize.
The utility model discloses realize processes such as schizolysis, combination, washing and elution of magnetic bead method through using different reagent container (deep hole board) at nucleic acid extraction's in-process, increased the experimental group number widely at a nucleic acid extraction's in-process, accelerated nucleic acid extraction widely, this equipment compact structure, small in size, operation are stable simultaneously, easily control, rate of heating is fast, has very big improvement on spatial layout, excellent in use effect.
The product creatively arranges the rack at the position of the rotating shaft of the station table through the arrangement of the rotating assembly, the rack can be kept fixed when the rotating assembly realizes the rotation of the station table, the spatial structure layout of the product is improved, the spatial structure and the size of the product are greatly reduced, and meanwhile, the nucleic acid extraction process is optimized, so that the station arrangement and the layout of the nucleic acid extraction process are improved, the placement of the station reagent container can be completed only by rotating the station table for one circle, the extraction process can be started immediately, and the repositioning is not needed.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
fig. 2 is a schematic view of the internal structure of the present invention;
fig. 3 is an exploded view of the rotating assembly.
Detailed Description
In the description of the present invention, the terms "upper", "lower", "front" and "rear" indicate the position or positional relationship based on the position or positional relationship shown in the drawings, and are only for convenience of description of the present invention rather than requiring the present invention to be constructed and operated in a specific position, and thus, should not be construed as limiting the present invention.
The following describes the present invention with reference to the accompanying drawings.
Referring to fig. 1-2, an anti-pollution nucleic acid extraction system, including a base 1, set up shell body 2 on base 1, set up the station 31 unit inside shell body 2, set up the extraction element that is used for nucleic acid extraction above station 31 unit, station 31 unit includes a station platform 3, be provided with the station 31 that is used for laying reagent container 32 on the station platform 3, station platform 3 is in station 31 department fretwork, shell body 2 upper portion is equipped with a plurality of inlet ports 41, be equipped with a plurality of ventholes 42 on base 1, venthole 42 department is equipped with negative pressure source 43. As a preferred scheme, the air inlet holes 41 are arranged at a place which is not easy to be directly observed at the upper part of the back surface of the outer shell 2, so that the overall aesthetic degree of the product is facilitated, the air inlet holes 41 are distributed in an array mode of 3 rows and 4 columns, the openings of the air inlet holes 41 are downward, and the dust is prevented from entering the inner part of the outer shell 2; the venthole 42 has 4, sets up respectively in 4 corners of base 1, and negative pressure source 43 is the negative pressure electric fan for the inside air current of shell body 2 is to pressure differential distribution evenly, improves anti-pollution efficiency and effect.
The venthole 42 and the negative pressure source 43 of anti-pollution system set up on base 1, can form a top-down air flow inside the nucleic acid extraction appearance when anti-pollution system starts for waste liquid waste gas that the nucleic acid extraction in-process produced can in time be got rid of downwards, avoids waste liquid waste gas and the sample in the reagent container 32 to mix and causes the pollution, and can reduce the sample that causes because of the air flow and volatilize.
Referring to fig. 2, preferably, a partition plate 44 is disposed under the working table 3, a support frame 45 for supporting the partition plate 44 is disposed on the base 1, and the partition plate 44 is provided with a vent hole 46 at a position corresponding to the working position 31 on the upper side of the negative pressure source 43, wherein the vent hole 46 is a honeycomb hole. The flow direction of air can be better guided to division board 44, improves anti-pollution effect, and division board 44 can keep apart the reagent that drips from station platform 3 simultaneously to the mechanism to station platform 3 downside plays the protection isolation effect. In addition, the partition plate 44 can also shield the internal structure of the extractor, thereby improving the visual effect of the extractor and improving the aesthetic degree.
Referring to fig. 2, the extraction unit preferably includes a frame 5, a stirring device and a magnetic attraction device disposed on the frame 5, and an up-and-down driving device for driving the stirring device and the magnetic attraction device to move up and down, the station 31 unit further includes a rotating assembly 9, the station table 3 can rotate around the rotating assembly 9, and the frame 5 is fixedly disposed on the rotating assembly 9. As the best embodiment, the reagent container 32 is a deep hole plate with 96 holes or 24 holes, the station table 3 is a rotary table, 8 stations 31 are uniformly arranged on the station table 3, a mounting structure matched with the deep hole plate is arranged at each station 31, the deep hole plate is arranged at the station 31, the station 31 for arranging the deep hole plate is hollow, different reagents are pre-arranged in the deep hole plate according to experimental requirements, and the deep hole plates on the 8 stations 31 comprise a sample deep hole plate, a deep hole plate for containing magnetic beads, a washing deep hole plate, an elution deep hole plate and the like. Of course, the number of stations 31 may be changed accordingly or different deep hole plates may be used, depending on experimental requirements.
The stirring device comprises a stirring frame 71, stirring consumables 72 arranged on the stirring frame 71, the magnetism suction device comprises a magnetic frame 61, a magnetic rod 62 arranged on the magnetic frame 61, the stirring consumables 72 comprise a plurality of stirring rods corresponding to reagent containers, the axis of each stirring rod is provided with a magnetism suction blind hole with an upward opening, the magnetic rod 62 can be inserted into the magnetism suction blind hole, and the up-and-down driving device comprises a stirring driving device 82 for driving the stirring frame 71 to move up and down and a magnetism suction driving device 81 for driving the magnetic frame 61 to move up and down.
The rotating assembly 9 comprises a rotating base 91 fixedly arranged on the base 1, a station seat 92 rotatably arranged on the rotating base 91 and a rack seat 93 used for installing a rack 5, a boss 95 used for limiting and bearing is arranged on the rotating base 91, the station seat 92 is arranged on the boss 95, the station platform 3 is arranged at the upper end of the station seat 92, a transmission piece 94 is arranged at the lower end of the station seat 92, the rotating driving device is in transmission connection with the transmission piece 94 and drives the station seat 92 to rotate so as to drive the station platform 3 to rotate, the lower side of the rack seat 93 is a connecting part 97, the upper side of the rack seat 96 is an installing part 96, a limiting part 98 used for limiting the upper side of the station seat 92 is arranged between the connecting part 97 and the installing part 96, the rack 5 is installed on the installing part 96, and the connecting part 97 is fixedly connected with the rotating base.
This product passes through the setting of rotating assembly 9, creatively sets up frame 5 in the position of station platform 3 rotation axis, can keep frame 5 fixed when rotating assembly 9 realizes station platform 3's rotation, the spatial structure overall arrangement of product has been improved, the spatial structure and the size of product have been reduced widely, the process of nucleic acid extraction has been optimized more simultaneously, make station 31 setting and the overall arrangement of nucleic acid extraction process improve, only need station platform 3 to rotate the round can accomplish placing of station 31 reagent container 32, need not to rotate many times and can place the deep hole board according to the nucleic acid extraction process, and can stand immediately and begin the extraction process, need not to relocate again.
During nucleic acid extraction, the extraction unit is fixed in the original position, the station table 3 is driven to rotate by the rotary driving device according to the experimental process, and the deep-hole plates on different stations 31 are used, so that the transfer of magnetic beads and samples between the deep-hole plates on different stations 31 is completed, and the process of nucleic acid extraction is completed. The utility model discloses realize processes such as schizolysis, combination, washing and elution of magnetic bead method through using different reagent container 32 (deep-hole board) at nucleic acid extraction's in-process, with present market nucleic acid extraction appearance completely different, increased the experimental group number widely at a nucleic acid extraction's an in-process, accelerated nucleic acid extraction widely, and this equipment structure is simple, novel, and easy operation is convenient, and nucleic acid extraction is effectual.
Variations and modifications to the above-described embodiments may occur to those skilled in the art, in light of the above teachings and teachings. Therefore, the present invention is not limited to the specific embodiments disclosed and described above, and some modifications and changes to the present invention should fall within the protection scope of the claims of the present invention. Furthermore, although specific terms are employed herein, they are used in a generic and descriptive sense only and not for purposes of limitation.
Claims (10)
1. A contamination-preventive nucleic acid extraction system characterized by: it includes a base, sets up shell body on the base, sets up at the inside station unit of shell body, sets up the unit of drawing that is used for nucleic acid to draw in station unit top, the station unit includes a station platform, and the station bench is provided with the station that is used for laying reagent container, and the station platform is in station department fretwork, shell body upper portion is equipped with a plurality of inlet ports, be equipped with a plurality of ventholes on the base, venthole department is equipped with the negative pressure source.
2. The anti-contamination nucleic acid extraction system of claim 1, wherein: the venthole has 4, sets up respectively 4 corners of base.
3. The anti-contamination nucleic acid extraction system of claim 1, wherein: the negative pressure source is a negative pressure electric fan.
4. The anti-contamination nucleic acid extraction system of claim 1, wherein: the lower side of the station platform is provided with a separation plate, the base is provided with a support frame for supporting the separation plate, and the separation plate is provided with an air vent at the position corresponding to the station on the upper side of the negative pressure source.
5. The anti-contamination nucleic acid extraction system of claim 4, wherein: the vent holes are honeycomb holes.
6. The anti-contamination nucleic acid extraction system of any one of claims 1 to 5, wherein: the extraction unit comprises a frame, a stirring device and a magnetic absorption device which are arranged on the frame, and an up-and-down driving device for driving the stirring device and the magnetic absorption device to move up and down.
7. The anti-contamination nucleic acid extraction system of claim 6, wherein: agitating unit includes the stirring frame, sets up the stirring consumptive material on the stirring frame, inhale the magnetic device and include magnetic frame, set up the magnetic rod on magnetic frame, the stirring consumptive material includes a plurality of stirring rods that correspond with reagent container, the stirring rod axle center is provided with the ascending magnetism blind hole of inhaling of opening, the magnetic rod can insert inhale the magnetism blind hole, drive arrangement inhales the magnetism drive arrangement including the stirring drive arrangement of drive stirring frame up-and-down motion and drive magnetic frame up-and-down motion from top to bottom.
8. The anti-contamination nucleic acid extraction system of claim 6, wherein: the station unit further comprises a rotating assembly, the station table can rotate around the rotating assembly, and the rack is fixedly arranged on the rotating assembly.
9. The anti-contamination nucleic acid extraction system of claim 8, wherein: the rotary assembly comprises a rotary base fixedly arranged on the base, a station seat rotatably arranged on the rotary base and a rack seat used for installing a rack, a transmission part in transmission connection with the rotary driving device is arranged at the lower end of the station seat, the station platform is arranged at the upper end of the station seat, and the rack seat is fixedly connected with the rotary base.
10. The anti-contamination nucleic acid extraction system of claim 9, wherein: the rotary base is provided with a boss for limiting and bearing, the station seat is arranged on the boss, the lower side of the rack seat is provided with a mounting part for connecting part and upper side, a limiting part for limiting the upper side of the station seat is arranged between the connecting part and the mounting part, the rack is mounted on the mounting part, and the connecting part is fixedly connected with the rotary base after passing through the station seat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920626202.5U CN210113275U (en) | 2019-04-30 | 2019-04-30 | Anti-pollution nucleic acid extraction system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920626202.5U CN210113275U (en) | 2019-04-30 | 2019-04-30 | Anti-pollution nucleic acid extraction system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210113275U true CN210113275U (en) | 2020-02-25 |
Family
ID=69579217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920626202.5U Active CN210113275U (en) | 2019-04-30 | 2019-04-30 | Anti-pollution nucleic acid extraction system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210113275U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111996101A (en) * | 2020-08-07 | 2020-11-27 | 襄阳市远杰精密机械有限公司 | Full-automatic nucleic acid extraction instrument with reduced sample pollution probability |
-
2019
- 2019-04-30 CN CN201920626202.5U patent/CN210113275U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111996101A (en) * | 2020-08-07 | 2020-11-27 | 襄阳市远杰精密机械有限公司 | Full-automatic nucleic acid extraction instrument with reduced sample pollution probability |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN206338921U (en) | Air cleaner | |
| CN107519709A (en) | Air cleaner | |
| CN210113275U (en) | Anti-pollution nucleic acid extraction system | |
| CN106867883B (en) | Automatic nucleic acid extraction instrument | |
| WO2015176548A1 (en) | Integrated processing mechanism for uniformly-mixing and filtering sample | |
| CN103861735B (en) | Magnetic separation device | |
| CN111154641A (en) | Full-automatic nucleic acid extraction amplifications detector | |
| CN212833819U (en) | Device for sorting cells by using magnetic beads | |
| CN115161188A (en) | Air microorganism detection system and method | |
| CN209584238U (en) | Magnetic method nucleic acid automatic extracting device | |
| CN212864734U (en) | Automatic nucleic acid extraction instrument | |
| CN210113279U (en) | Novel nucleic acid extraction appearance | |
| EP4050336A1 (en) | Enricher, enrichement system, sample manufacturing system, and sample detection system | |
| CN109442579A (en) | Self-cleaning aeration device | |
| CN216620159U (en) | Air purifier | |
| CN216367351U (en) | A exhaust treatment device for enameled wire processing | |
| CN209911052U (en) | Sampling device for chemical analysis and detection | |
| CN208642048U (en) | A kind of chemical laboratory emission-control equipment | |
| CN208373116U (en) | A kind of easy-to-dismount micro-fluidic chip | |
| CN207483723U (en) | A kind of instrument for extracting nucleic acid | |
| CN110988328A (en) | Full-automatic fluorescence labeling single cell suspension preparation device and matched sample loading tube | |
| CN109847467B (en) | Medical clean bench | |
| CN212264114U (en) | Laboratory fume chamber | |
| CN109576151A (en) | Magnetic method nucleic acid automatic extracting device | |
| CN218989291U (en) | Magnetic attraction mechanism and sample extraction equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |