CN208373116U - A kind of easy-to-dismount micro-fluidic chip - Google Patents

A kind of easy-to-dismount micro-fluidic chip Download PDF

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Publication number
CN208373116U
CN208373116U CN201820759365.6U CN201820759365U CN208373116U CN 208373116 U CN208373116 U CN 208373116U CN 201820759365 U CN201820759365 U CN 201820759365U CN 208373116 U CN208373116 U CN 208373116U
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CN
China
Prior art keywords
slot
easy
waste liquid
detection
fluidic chip
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201820759365.6U
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Chinese (zh)
Inventor
陈雪叶
刘彦琳
张真
吴中立
韩文博
郑跃
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Liaoning University of Technology
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Liaoning University of Technology
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Filing date
Publication date
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Priority to CN201820759365.6U priority Critical patent/CN208373116U/en
Application granted granted Critical
Publication of CN208373116U publication Critical patent/CN208373116U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of easy-to-dismount micro-fluidic chips, including chip body and shell, chip body includes cover plate and substrate, substrate left end sets loading slot, mixing channel is set on the right side of loading slot, detection slot is set on the right side of mixing channel, waste liquid tank is set on the right side of detection slot, loading slot, mixing channel, miniflow access is set between detection slot and waste liquid tank, cover plate is set above substrate, cover plate left end is set plus sample holes, mix aperture is set on the right side of well, detection hole is set on the right side of mix aperture, waste liquid hole is set on the right side of detection hole, shell is made of outer housing and inner housing, outer housing sets four sample-adding frames, shell intracoelomic cavity sets sliding rail, inner housing lower end sets sliding slot, inner housing bottom surface sets circular hole, inner housing surrounding sets raised baffle.The utility model is analyzed automatically using micro-fluidic chip, detects work, and the sample size needed is few, and testing result accuracy is high, favorable reproducibility, while sliding slot, sliding rail and the circular hole structure being arranged, and makes chip convenient disassembly.

Description

A kind of easy-to-dismount micro-fluidic chip
Technical field
The utility model relates to a kind of micro fluidic chip technical field, specifically a kind of easy-to-dismount micro-fluidic chip.
Background technique
Microfluidic chip technology is basic biology, chemistry, the sample preparation of medical analysis process, reaction, separation, detection etc. Operating unit is integrated on the chip of one piece of micro-meter scale, is automatically performed analysis overall process, its production raw material are mainly by each Kind glass, quartz, silicon wafer, polymer material, elastic material and metal etc., are mainly used in the fields such as biology, chemistry, medicine, Especially in terms of analysis, inspection, act on huge.
It analyzed using microfluidic chip technology, examine that few with amount of samples, detection accuracy is high, favorable reproducibility Advantage, and directly micro-fluidic chip is fixedly mounted for most equipment, dismantles very inconvenient when something goes wrong, and replacement is more tired Difficulty, therefore the problem of a kind of easy-to-dismount micro-fluidic chip becomes current urgent need to resolve is provided.
Summary of the invention
1, it to solve the problems, such as
Directly micro-fluidic chip is fixedly mounted for existing most equipment, dismantle when something goes wrong it is very inconvenient, Replacement more difficult problem, it is above-mentioned to solve the purpose of this utility model is to provide a kind of easy-to-dismount micro-fluidic chip The problem of being proposed in background technique.
2, technical solution
To achieve the above object, the utility model provides the following technical solutions:
A kind of easy-to-dismount micro-fluidic chip, including chip body and shell, the chip body include cover plate and base Piece, the substrate left end are set there are four loading slot, and the loading slot right side is equipped with mixing channel, is equipped with detection on the right side of the mixing channel Slot, the detection slot right side are equipped with waste liquid tank, miniflow access are equipped between the loading slot, mixing channel, detection slot and waste liquid tank, Cover plate is equipped with above the substrate, the cover plate left end is equipped with well, and the well is oppositely arranged and constitutes with loading slot Sample addition zone, the well right side are equipped with mix aperture, and the mix aperture and mixing channel are oppositely arranged and constitute mixing chamber, described mixed It closes and is equipped with detection hole on the right side of hole, the detection hole and detection slot are oppositely arranged and constitute sensing chamber, setting on the right side of the detection hole Waste liquid hole, the waste liquid hole and waste liquid tank are oppositely arranged and constitute waste liquid chamber, and the shell is made of outer housing and inner housing, institute It states outer housing side and is equipped with opening, set that there are four be loaded frame, the shell intracoelomic cavity bottom face on the left of the outer housing upper surface It is respectively arranged on the left side and the right side sliding rail, sliding slot is respectively set at left and right sides of the inner housing lower end surface, the inner housing bottom surface is equipped with Circular hole, the inner housing surrounding edge are equipped with raised baffle.
As a further solution of the present invention: the cover plate and substrate are glass material, and size, shape complete one It causes.
The substrate is connected by way of glue envelope integral with cover plate as a further solution of the present invention,.
The well is identical as loading slot openings of sizes, shape as a further solution of the present invention,.
The mix aperture is identical as mixing channel openings of sizes, shape as a further solution of the present invention,.
The detection hole is identical as detection slot openings of sizes, shape as a further solution of the present invention,.
The waste liquid hole is identical as waste liquid tank openings of sizes, shape as a further solution of the present invention,.
The sample-adding frame and the sample addition zone of chip Your Majesty are oppositely arranged as a further solution of the present invention,.
The outer housing is slidably connected inner housing as a further solution of the present invention,.
The inner housing is sunk structure and shape, size and chip master as a further solution of the present invention, Body is identical.
3, beneficial effect
Compared with prior art, the utility model has the beneficial effects that
(1) the utility model carries out detection work using micro-fluidic chip, and the sample size needed is few, testing result accuracy Height, favorable reproducibility.
(2) the utility model is equipped with sliding slot, sliding rail and circular hole, chip convenient disassembly.
(3) chip body of the utility model includes double-layer structure, and separately manufactured work efficiency is high.
(4) the utility model connects sample addition zone, mixing chamber, sensing chamber and waste liquid chamber by setting miniflow access, automatic complete It is easy to operate at analysis, checkout procedure.
(5) the utility model does production material using glass, and production cost is low, and manufacturing process is simple.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of easy-to-dismount micro-fluidic chip.
Fig. 2 is the structural schematic diagram of chip body in easy-to-dismount micro-fluidic chip.
Fig. 3 is the cross-sectional view of chip body in easy-to-dismount micro-fluidic chip.
Fig. 4 is the structural schematic diagram of shell in easy-to-dismount micro-fluidic chip.
In figure: 1- chip body;2- shell;3- cover plate;4- substrate;5- circular hole;6- loading slot;7- mixing channel;8- Detection slot;9- waste liquid tank;10- miniflow access;11- well;12- mix aperture;13- detection hole;14- waste liquid hole;15- sample-adding Room;16- mixing chamber;17- sensing chamber;18- waste liquid chamber;19- outer housing;20- inner housing;21- is loaded frame;22- baffle.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, the range that subordinate protects in the utility model.
Please refer to Fig. 1~4, in the utility model embodiment, a kind of easy-to-dismount micro-fluidic chip, including chip body 1 and shell 2, the chip body 1 includes cover plate 3 and substrate 4, and the cover plate 3 and substrate 4 are glass material, 3 He of cover plate 4 size of substrate, shape are completely the same, and 4 left end of substrate is set there are four loading slot 6, and mixing channel is equipped on the right side of the loading slot 6 7, detection slot 8 is equipped on the right side of the mixing channel 7, is equipped with waste liquid tank 9 on the right side of the detection slot 8, the loading slot 6, mixing channel 7, Detection slot 8 and waste liquid tank 9 are located on a horizontal line, are equipped between the loading slot 6, mixing channel 7, detection slot 8 and waste liquid tank 9 Miniflow access 10, is equipped with cover plate 3 above the substrate 4, the substrate 4 connected by way of glue envelope with cover plate 3 it is integral, it is described 3 left end of cover plate is equipped with plus sample holes 11, and the well 11 is identical with 6 openings of sizes of loading slot, shape, the well 11 and Loading slot 6 is oppositely arranged and constitutes sample addition zone 15, is equipped with mix aperture 12 on the right side of the well 11, the mix aperture 12 with mix 7 openings of sizes of slot, shape are identical, and the mix aperture 12 is oppositely arranged and constitutes mixing chamber 16, the mix aperture 12 with mixing channel 7 Right side is equipped with detection hole 13, and the detection hole 13 is identical as 8 openings of sizes of detection slot, shape, the detection hole 13 and detection slot 8 It is oppositely arranged and is constituted sensing chamber 17, waste liquid hole 14 is set on the right side of the detection hole 13, the waste liquid hole 14 is open with waste liquid tank 9 Size, shape are identical, and the waste liquid hole 14 is oppositely arranged and constitutes waste liquid chamber 18 with waste liquid tank 9, logical using the miniflow on substrate 4 Sample addition zone 15, mixing chamber 16, sensing chamber 17 can be connected to by road 10 with waste liquid chamber 18, and the shell 1 is by outer housing 19 and interior Shell 20 is constituted, and 19 side of outer housing is equipped with opening, sets that there are four be loaded frame 21, institute on the left of 19 upper surface of outer housing It states sample-adding frame 21 to be oppositely arranged with the sample addition zone 15 in chip body 1, at left and right sides of the 19 inner cavity bottom face of outer housing respectively Equipped with sliding rail, the outer housing 19 is slidably connected inner housing 20, and sliding slot is respectively set at left and right sides of 20 lower end surface of inner housing, The sliding slot is correspondingly arranged with sliding rail, and the inner housing 20 is sunk structure, the recess of inner housing 20 size, shape and chip Main body 1 is identical, can be stuck in chip body 1 in inner housing 20 is recessed, 20 bottom surface of inner housing is equipped with circular hole 5, convenient Chip body 1 is dismantled, and 20 surrounding edge of inner housing is equipped with raised baffle 22.
The working principle of the utility model is: need to first pull open shell 2 when work, chip body 1 is put into inner housing 20, is led to It crosses the sample-adding frame 21 on shell 2 multiple samples and reagent are added in sample addition zone 15 respectively, sample and reagent pass through miniflow access 10, which sequentially enter mixing chamber 16, is mixed, then enters control laboratory 17 by miniflow access 10, is completed after examining in control laboratory 17 Solution enters waste liquid chamber 18, finally takes out chip body 1, is cleared up.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting Related claim.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (10)

1. a kind of easy-to-dismount micro-fluidic chip, including chip body (1) and shell (2), which is characterized in that the chip master Body (1) includes cover plate (3) and substrate (4), and substrate (4) left end is set there are four loading slot (6), on the right side of the loading slot (6) Equipped with mixing channel (7), detection slot (8) are equipped on the right side of the mixing channel (7), are equipped with waste liquid tank (9) on the right side of the detection slot (8), Miniflow access (10) are equipped between the loading slot (6), mixing channel (7), detection slot (8) and waste liquid tank (9), the substrate (4) Top is equipped with cover plate (3), and cover plate (3) left end is equipped with well (11), and the well (11) is opposite with loading slot (6) to be set It sets and constitutes sample addition zone (15), be equipped with mix aperture (12) on the right side of the well (11), the mix aperture (12) and mixing channel (7) It is oppositely arranged and constitutes mixing chamber (16), be equipped with detection hole (13) on the right side of the mix aperture (12), the detection hole (13) and inspection It surveys slot (8) to be oppositely arranged and constitute sensing chamber (17), waste liquid hole (14) is set on the right side of the detection hole (13), the waste liquid hole (14) it is oppositely arranged and constitutes waste liquid chamber (18) with waste liquid tank (9), the shell (2) is by outer housing (19) and inner housing (20) structure At outer housing (19) side is equipped with opening, is set on the left of outer housing (19) upper surface there are four sample-adding frame (21), described Outer housing (19) inner cavity bottom face is respectively arranged on the left side and the right side sliding rail, is respectively set at left and right sides of inner housing (20) lower end surface Sliding slot, inner housing (20) bottom surface are equipped with circular hole (5), and inner housing (20) surrounding edge is equipped with raised baffle (22)。
2. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the cover plate (3) and substrate (4) For glass material, and size, shape are completely the same.
3. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the substrate (4) and cover plate (3) It is connected by way of glue envelope integral.
4. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the well (11) and sample-adding Slot (6) openings of sizes, shape are identical.
5. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the mix aperture (12) with mix Slot (7) openings of sizes, shape are identical.
6. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the detection hole (13) and detection Slot (8) openings of sizes, shape are identical.
7. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the waste liquid hole (14) and useless Liquid bath (9) openings of sizes, shape are identical.
8. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the sample-adding frame (21) and chip Sample addition zone (15) in main body (1) is oppositely arranged.
9. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that outer housing (19) sliding connects Connect inner housing (20).
10. easy-to-dismount micro-fluidic chip according to claim 1, which is characterized in that the inner housing (20) is recessed It falls into structure and shape, size is identical as chip body (1).
CN201820759365.6U 2018-05-22 2018-05-22 A kind of easy-to-dismount micro-fluidic chip Expired - Fee Related CN208373116U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820759365.6U CN208373116U (en) 2018-05-22 2018-05-22 A kind of easy-to-dismount micro-fluidic chip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820759365.6U CN208373116U (en) 2018-05-22 2018-05-22 A kind of easy-to-dismount micro-fluidic chip

Publications (1)

Publication Number Publication Date
CN208373116U true CN208373116U (en) 2019-01-15

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Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113281499A (en) * 2021-05-18 2021-08-20 厦门先明生物技术有限公司 Microfluidic immunoassay joint detection device and using method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113281499A (en) * 2021-05-18 2021-08-20 厦门先明生物技术有限公司 Microfluidic immunoassay joint detection device and using method thereof

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20190115

Termination date: 20190522