CN204807462U - Saliva sample chemical examination device - Google Patents
Saliva sample chemical examination device Download PDFInfo
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- CN204807462U CN204807462U CN201520558508.3U CN201520558508U CN204807462U CN 204807462 U CN204807462 U CN 204807462U CN 201520558508 U CN201520558508 U CN 201520558508U CN 204807462 U CN204807462 U CN 204807462U
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- saliva sample
- assay device
- saliva
- reagent strip
- sample
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Abstract
The utility model provides a saliva sample chemical examination device, including side flow reagent strip, and this side flow reagent strip including the sample portion that is used for receiving the saliva sample, have chemical reagent's test portion and be located connecting portion between sample portion and the test portion, wherein: sample portion includes the base plate and is used for the filter layer of the particle of filtering saliva sample median, the filter layer is located base plate upper surface and thickness are more than or equal to 0.5 millimeter, flow through the saliva sample of filter layer is absorbed by connecting portion and carries test portion and chemical reagent to produce chemical reaction. The utility model discloses an increase the filter layer that has certain thickness in sample portion, the filtering particle in the saliva that awaits measuring to make other parts of waiting to incline in the saliva can flow smoothly to test portion, accuracy that the reinforcing was test.
Description
Technical field
The utility model relates to fluid test device, more particularly, relates to a kind of device saliva sample being implemented to chemical examination.
Background technology
Lateral flow devices is for whether there is the simplification experiment device detecting target in test sample book.At present, lateral flow devices has been applied in various types of test, comprises pregnancy tests, HIV test and malaria test etc.The test sample book of lateral flow devices can be such as urinate, saliva, blood or fecal sample etc.
Publication number is that European patent discloses of EP1277053 is a kind of for comprising the method and apparatus that saliva carries out diagnostic test to mouth cavity fluid.When this patent is mainly used in solving sputum test, saliva sample is not along the problem of lateral flow test strip flowing.EP1277053 patent is thought, the immobilising main cause of saliva sample is that the relative concentration of the protein material of mucin and other viscosity in sample is higher.This patent is by increasing a pad portion in a device, and this pad portion has salt or other known decomposable asymmetric choice net and the reduction mucin decomposed substance containing the viscosity of mucin fluid.Above-mentioned pad portion specifically can be made up of fiber reinforced glass matrix, to filter separated protein material and other microparticle material from test sample book.By this device, it can be made to move along test-strips without the need to carrying out pre-service to saliva, thus can facilitate and test relatively little saliva sample rapidly.
The pad portion disclosed in EP1277053 patent comprises die-cut portion, and this die-cut portion has the commercial fiber glass materials of about 0.2 mm of thickness.Above-mentioned pad portion can be positioned at indwelling to be had on the bonding pad of detection reagent.Saliva sample is placed in the fiberglass packing portion for decomposing mucin material, and mucin material is subsequently by the glass fiber filter in the glass fibre in pad portion and bottom glass fibre sample pad.Then test sample book is through bonding pad, herein, if assay is present in test sample book, chemical reaction occurs.Then test sample book enters the trapping region that test result can be read.
Chemically examine for some saliva, comprise pepsin analysis, saliva fully can be flowed to obtain test result along above-mentioned lateral flow test strip.But in the test of about 10%, saliva is not fully flowed.
Utility model content
The technical problems to be solved in the utility model is, for the problem that salivary flow under partial picture in above-mentioned lateral flow devices is insufficient, provides a kind of saliva sample assay device.
The technical scheme that the utility model solves the problems of the technologies described above is, a kind of saliva sample assay device is provided, comprise effluent reagent strip, and this effluent reagent strip comprising specimen port for receiving saliva sample, having the test department of chemical reagent and the connecting portion between described specimen port and test department, wherein: described specimen port comprises substrate and the filtering layer for the particulate in filtering saliva sample; Described filtering layer is positioned at described upper surface of base plate and thickness is more than or equal to 0.5 millimeter; The saliva sample flowing through described filtering layer is absorbed by connecting portion and is transported to test department and chemical reagent produces chemical reaction.
In saliva sample assay device described in the utility model, described device also comprises the housing fastened by upper casing and lower casing, and described effluent reagent strip is placed in this housing.
In saliva sample assay device described in the utility model, described upper casing has sample cell and detection window, and the outlet of described sample cell just to the specimen port of the effluent reagent strip in housing, detection window just to the test department of effluent reagent strip.
In saliva sample assay device described in the utility model, described lower casing has the placement position for placing effluent reagent strip, and on described placement position the position of the specimen port of corresponding effluent reagent strip higher than the position of corresponding test department.
In saliva sample assay device described in the utility model, described sample cell is infundibulate and outlet is positioned at bottom.
In saliva sample assay device described in the utility model, described sample site is in the first end of effluent reagent strip, and the second end of described effluent reagent strip also has the absorbent portion be connected with test department.
In saliva sample assay device described in the utility model, described filtering layer is made up of adhesive-free fiber type.
In saliva sample assay device described in the utility model, described connecting portion is made up of adhesive-free fiber type, and described test department is made up of the nitrocellulose membrane with chemical reagent.
In saliva sample assay device described in the utility model, described adhesive-free fiber type is borosilicate glass mocrofibers dimension.
In saliva sample assay device described in the utility model, the thickness of described filtering layer is between 0.5 millimeter and 1 millimeter.
Saliva sample assay device of the present utility model has following beneficial effect: by having certain thickness filtering layer in specimen port increase, particulate in filtering saliva to be measured, thus make to treat other parts in the saliva of side can smooth flow to test department, strengthen the accuracy of chemical examination.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the utility model saliva sample assay device embodiment.
Fig. 2 be in Fig. 1 effluent reagent strip along the sectional view of A-A line.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the utility model is further elaborated.It is emphasized that specific embodiment described herein is only in order to explain the utility model, and be not used in restriction the utility model.
Fig. 1 is the schematic diagram of the utility model saliva sample assay device embodiment, and this device can be used for carrying out different classes of chemical examination to saliva sample.Saliva sample assay device in the present embodiment comprises effluent reagent strip 30, and this effluent reagent strip 30 comprising specimen port for receiving saliva sample, having the test department 33 of chemical reagent and the connecting portion 32 between specimen port and test department 33.Above-mentioned specimen port comprises substrate 35 and the filtering layer 31 for the particulate in filtering saliva sample, and wherein filtering layer 31 is adhesively fixed on the upper surface of substrate 35 and the thickness of this filtering layer 31 is more than or equal to 0.5 millimeter (preferably between 0.75 millimeter and 1 millimeter).The saliva sample flowing through filtering layer 31 from top is absorbed by connecting portion 32 and carries (passing through capillary action) to produce chemical reaction to test department 33 and chemical reagent, and shows result of laboratory test.
Above-mentioned filtering layer 31 specifically can be made up of adhesive-free fiber type (such as borosilicate glass mocrofibers dimension).Correspondingly, connecting portion 32 also can be made up of adhesive-free fiber type.
Along with saliva to be measured passes filtering layer 31 by capillary flow, be wherein greater than the particulate of specific dimensions by filtering, other composition is then slowly also released into connecting portion 32 constantly.Filtered saliva sample, through fixed substrate 35 aquation, migrates to test department 33 subsequently and produces chemical reaction with chemical reagent, and show result of laboratory test by modes such as color changes.Test department 33 can be made up of nitrocellulose membrane and corresponding chemical reagent.
Above-mentioned saliva sample assay device also can comprise housing, and this shell is formed (such as by the bayonet fittings of the card column 21 on lower casing 20 with upper casing 10) by upper casing 10 and lower casing 20 fastening, and effluent reagent strip 30 is placed in this housing.Especially, upper casing 10 has sample cell 11 and detection window 12, and the outlet of sample cell 11 just to the specimen port (filtering layer 31) of the effluent reagent strip 30 in housing, detection window 12 just to the test department 33 of effluent reagent strip 30.Enter housing for ease of saliva to be measured and reach filtering layer 31, the sample cell 11 on upper casing 10 is for infundibulate and outlet is positioned at bottom.
Lower casing 20 then has the placement position 22 for placing effluent reagent strip 30, and place the position of position higher than test department of the specimen port of corresponding effluent reagent strip 30 on position 22, thus saliva to be measured can be moved to test section under gravity and not reflux.
In above-mentioned effluent reagent strip 30, specimen port can be positioned at the first end of effluent reagent strip 30, and the second end of this effluent reagent strip 30 also has the absorbent portion 34 be connected with test department 33.Like this, the residue saliva to be measured flowing to test department 33 is extracted out by absorbent portion 34 by the capillary action continued.
In saliva sample assay device described in the utility model, the thickness of described filtering layer is between 0.75 millimeter and 1 millimeter.
The above; be only the utility model preferably embodiment; but protection domain of the present utility model is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the utility model discloses; the change that can expect easily or replacement, all should be encompassed within protection domain of the present utility model.Therefore, protection domain of the present utility model should be as the criterion with the protection domain of claim.
Claims (10)
1. a saliva sample assay device, it is characterized in that: comprise effluent reagent strip, and this effluent reagent strip comprising specimen port for receiving saliva sample, having the test department of chemical reagent and the connecting portion between described specimen port and test department, wherein: described specimen port comprises substrate and the filtering layer for the particulate in filtering saliva sample; Described filtering layer is positioned at described upper surface of base plate and thickness is more than or equal to 0.5 millimeter; The saliva sample flowing through described filtering layer is absorbed by connecting portion and is transported to test department and chemical reagent produces chemical reaction.
2. saliva sample assay device according to claim 1, is characterized in that: described device also comprises the housing fastened by upper casing and lower casing, and described effluent reagent strip is placed in this housing.
3. saliva sample assay device according to claim 2, it is characterized in that: described upper casing has sample cell and detection window, and the outlet of described sample cell just to the specimen port of the effluent reagent strip in housing, described detection window just to the test department of effluent reagent strip.
4. saliva sample assay device according to claim 3, is characterized in that: described lower casing has the placement position for placing effluent reagent strip, and on described placement position the position of the specimen port of corresponding effluent reagent strip higher than the position of corresponding test department.
5. saliva sample assay device according to claim 3, is characterized in that: described sample cell is infundibulate and outlet is positioned at bottom.
6. saliva sample assay device according to claim 1, is characterized in that: described sample site is in the first end of effluent reagent strip, and the second end of described effluent reagent strip also has the absorbent portion be connected with test department.
7. the saliva sample assay device according to any one of claim 1-6, is characterized in that: described filtering layer is made up of adhesive-free fiber type.
8. saliva sample assay device according to claim 7, it is characterized in that: described connecting portion is made up of adhesive-free fiber type, described test department is made up of the nitrocellulose membrane with chemical reagent.
9. saliva sample assay device according to claim 8, is characterized in that: described adhesive-free fiber type is borosilicate glass mocrofibers dimension.
10. saliva sample assay device according to claim 1, is characterized in that: the thickness of described filtering layer is between 0.5 millimeter and 1 millimeter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520558508.3U CN204807462U (en) | 2015-07-29 | 2015-07-29 | Saliva sample chemical examination device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520558508.3U CN204807462U (en) | 2015-07-29 | 2015-07-29 | Saliva sample chemical examination device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204807462U true CN204807462U (en) | 2015-11-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520558508.3U Active CN204807462U (en) | 2015-07-29 | 2015-07-29 | Saliva sample chemical examination device |
Country Status (1)
| Country | Link |
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| CN (1) | CN204807462U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106596537A (en) * | 2016-12-15 | 2017-04-26 | 四川沃文特生物技术有限公司 | Reagent card shell |
| US20190324018A1 (en) * | 2018-04-19 | 2019-10-24 | Mark D. Noar | Saliva reagent strip for detecting concentration of pepsin or pepsinogen |
-
2015
- 2015-07-29 CN CN201520558508.3U patent/CN204807462U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106596537A (en) * | 2016-12-15 | 2017-04-26 | 四川沃文特生物技术有限公司 | Reagent card shell |
| US20190324018A1 (en) * | 2018-04-19 | 2019-10-24 | Mark D. Noar | Saliva reagent strip for detecting concentration of pepsin or pepsinogen |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170616 Address after: British Hull KARs Castle Hill Hospital Lu Daisy Building 2 Patentee after: Yadi biomedical Co.,Ltd. Address before: Hull City, England Patentee before: TECHNOSTICS LTD. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230609 Address after: 26-23 Huibei Road, Liangxi District, Wuxi City, Jiangsu Province Patentee after: Meian innovative medical technology Wuxi Co.,Ltd. Address before: Hull tower, Castle Hill Hospital, 2 floor, Daisy building, UK Patentee before: Yadi biomedical Co.,Ltd. |