CN209446355U - Pattern detection structure and biological detection platform - Google Patents

Pattern detection structure and biological detection platform Download PDF

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Publication number
CN209446355U
CN209446355U CN201822080580.6U CN201822080580U CN209446355U CN 209446355 U CN209446355 U CN 209446355U CN 201822080580 U CN201822080580 U CN 201822080580U CN 209446355 U CN209446355 U CN 209446355U
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China
Prior art keywords
sample
pattern detection
runner
fluid channel
detection structure
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CN201822080580.6U
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Chinese (zh)
Inventor
刘远昭
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Shanghai weiruibo Biotechnology Co., Ltd
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Abot Nanobiological Technology Co Ltd
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Abstract

The utility model provides a kind of pattern detection structure, which includes overflow plate, offers buffer runner;Filter plate, for filtering sample to be tested, filter plate offers sample runner;Test board, for testing sample to be tested, test board is connected to buffer runner, sample runner.Pattern detection structure provided by the utility model, buffer runner and sample runner are quantitative chamber, by the way that overflow plate and filter plate is separately positioned, buffer and sample can be accurately controlled respectively into the flow in the pattern detection structure, improves the accuracy of fluid sample quantitative detection.

Description

Pattern detection structure and biological detection platform
Technical field
The utility model belongs to biological monitor technical field, is to be related to a kind of pattern detection structure more specifically And biological detection platform.
Background technique
In the medical field, in order to diagnose the reasons such as the cause of disease, forensic identification, drug test, it will usually use detecting instrument The body fluid samples such as blood, urine, saliva are detected, testing result is judged according to the content of various types of cells in analysis sample. Before and after sample imports instrument, it is required to clean the detection module of instrument.In blood sample test, blood Sample also needs first to be settled and filtered etc. operation.In current test equipment, blood filtration module and cleaning module are usual In the same flow-path module, quantitatively control it is inclined can not to may cause testing result into the flow of liquid in modules Difference.
Utility model content
The purpose of this utility model is to provide a kind of pattern detection structures, existing in the prior art without legal to solve The technical issues of amount control enters the flow of liquid in modules, may cause testing result deviation.
In order to achieve the above purposes, the technical solution adopted by the utility model is: provides a kind of pattern detection structure, comprising:
Overflow plate offers buffer runner;
Filter plate, for filtering sample to be tested, the filter plate offers sample runner;
Test board, for testing sample to be tested, the test board connects with the buffer runner, the sample runner It is logical.
Further, the buffer runner include buffer sap cavity, with it is described buffer sap cavity be connected to fluid channel, with it is described The waste liquid chamber of fluid channel connection, the bottom wall of the fluid channel offer the reaction mouth that the test board is flowed into for buffer.
Further, the overflow plate has the circumferential rib for being located on the reaction mouth, institute towards the test board side Circumferential rib is stated to abut against with the test board.
Further, the depth of the buffering sap cavity is greater than the depth of the fluid channel, and the depth of the waste liquid chamber is greater than The depth of the fluid channel.
Further, the first choked flow boss for preventing buffer from flowing back is equipped at the bottom wall of fluid channel entrance, it is described The second choked flow boss for preventing waste reflux is equipped at the bottom wall of fluid channel outlet.
Further, check (non-return) valve, the width of the check (non-return) valve are additionally provided between the first choked flow boss and the fluid channel Degree is less than the width of the fluid channel.
Further, the inlet and exit of the buffering sap cavity are equipped with multiple water conservancy diversion microtrabeculaes being spaced apart from each other.
Further, the filter plate, the test board are set to the same side of the overflow plate.
Further, the avoid holes that the sample runner is flowed into for sample are offered on the overflow plate.
The another object of the utility model is to provide a kind of biological detection platform, including above-mentioned pattern detection structure.
Pattern detection structure provided by the utility model and the beneficial effect of biological detection platform are: with prior art phase Than overflow plate has buffer runner in the utility model pattern detection structure, and filter plate has sample runner, and buffer can be through It crosses buffer runner and enters and clean test board in test board, sample, which can enter test board by sample runner, to be tested, and is buffered Liquid stream road and sample runner are quantitative chamber, by the way that overflow plate and filter plate is separately positioned, can accurately be controlled respectively slow Fliud flushing and sample enter the flow in the pattern detection structure, improve the accuracy of fluid sample quantitative detection.
Detailed description of the invention
It, below will be to embodiment or the prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model Attached drawing needed in description is briefly described, it should be apparent that, the accompanying drawings in the following description is only that this is practical new Some embodiments of type for those of ordinary skill in the art without any creative labor, can be with It obtains other drawings based on these drawings.
Fig. 1 is the structure chart of pattern detection structure provided by the embodiment of the utility model;
Fig. 2 is the detonation configuration figure of pattern detection structure provided by the embodiment of the utility model;
Fig. 3 is the structure chart one of overflow plate provided by the embodiment of the utility model;
Fig. 4 is the structure chart two of overflow plate provided by the embodiment of the utility model;
Fig. 5 is the structure chart of the first filter plate provided by the embodiment of the utility model;
Fig. 6 is the structure chart of second of filter plate provided by the embodiment of the utility model;
Fig. 7 is the structure chart of the third filter plate provided by the embodiment of the utility model;
Fig. 8 is the structure chart of test board provided by the embodiment of the utility model.
Wherein, each appended drawing reference in figure:
3- overflow plate;301- avoid holes;31- buffers sap cavity;311- propulsive liquid mouth;312- water conservancy diversion microtrabeculae;32- fluid channel; 3201- reacts mouth;3202- sample inflow hole;321- the first choked flow boss;322- check (non-return) valve;323- the second choked flow boss;33- Waste liquid chamber;34- circumferential rib;4- filter plate;401- sample runner;5- test board;51- test section;52- signal conversion part;53- letter Number contact.
Specific embodiment
In order to which technical problem to be solved in the utility model, technical solution and beneficial effect is more clearly understood, with Lower combination accompanying drawings and embodiments, the present invention will be further described in detail.It should be appreciated that specific reality described herein It applies example to be only used to explain the utility model, is not used to limit the utility model.
It should be noted that it can be directly another when element is referred to as " being fixed on " or " being set to " another element On one element or indirectly on another element.When an element is known as " being connected to " another element, it can To be directly to another element or be indirectly connected on another element.
It is to be appreciated that term " length ", " width ", "upper", "lower", "front", "rear", "left", "right", "vertical", The orientation or positional relationship of the instructions such as "horizontal", "top", "bottom" "inner", "outside" is that orientation based on the figure or position are closed System, is merely for convenience of describing the present invention and simplifying the description, rather than the device or element of indication or suggestion meaning are necessary It with specific orientation, is constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include one or more of the features.The meaning of " plurality " is two or two in the description of the present invention, More than, unless otherwise specifically defined.
Fig. 1 and Fig. 2 is please referred to, now pattern detection structure provided by the utility model is illustrated.The pattern detection knot Structure includes overflow plate 3, filter plate 4 and test board 5.Buffer runner is offered on overflow plate 3, offers sample on filter plate 4 Runner 401, buffer runner and sample runner 401 are quantitative chamber, can be precisely controlled the flow of buffer and sample.Filtering Plate 4 is for filtering sample to be tested, such as when sample to be tested is blood, and filter plate 4 is for the haemocyte in filtering blood.Test board 5 for testing sample to be tested, and test board 5 is connected to buffer runner, sample runner 401.When being rinsed, buffer warp Buffer runner is crossed, is then flowed into test board 5, test board 5 is rinsed;When testing, sample passes through 401 mistake of sample runner It is flowed into test board 5 after filter, test board 5 tests sample.
Pattern detection structure provided by the utility model, compared with prior art, the pattern detection that the use of the new type provides Overflow plate 3 has buffer runner in structure, and filter plate 4 has sample runner 401, and buffer can enter by buffer runner Test board is cleaned in test board 5, sample, which can enter test board 5 by sample runner, to be tested, buffer runner and sample flow Road is quantitative chamber, by the way that overflow plate 3 and filter plate 4 is separately positioned, can accurately control respectively buffer and sample into Enter the flow in the pattern detection structure, improves the accuracy of fluid sample quantitative detection.
In one of the embodiments, referring to Fig. 2, a kind of tool as pattern detection structure provided by the utility model Body embodiment, overflow plate 3 abut setting with upper cover plate 2, and filter plate 4 abuts setting, and filter plate 4 and test with overflow plate 3 Plate 5 is set to the same side of overflow plate 3, and overflow plate 3 is set between upper cover plate 2 and test board 5.In this way, sample enters filter plate 4 When, need to offer avoid holes 301, avoid holes 301 and sample entrance port 202 and sample runner on overflow plate 3, overflow plate 3 401 entrance faces, and sample is entered in sample runner 401 by the avoid holes 301.
Fig. 3 and Fig. 4 is please referred in one of the embodiments, as pattern detection structure provided by the utility model A kind of specific embodiment, buffer runner include the fluid channel 32 and fluid channel for buffering sap cavity 31, being connected to buffering sap cavity 31 The waste liquid chamber 33 of 32 connections, the bottom wall of fluid channel 32 offer the reaction mouth 3201 that test board 5 is flowed into for buffer.Buffer into After entering to buffer sap cavity 31, fluid channel 32 is flowed into, test board 5 is flowed by reaction mouth 3201, flows into waste liquid chamber after rinsing test board 5 33.Optionally, buffering 31 inlet of sap cavity has propulsive liquid mouth 311 compatible with buffer inlet 201, makes to buffer sap cavity 31 The side wall of side wall and buffer inlet 201 is tightly connected.Optionally, the quantity of reaction mouth 3201 is multiple, along fluid channel 32 Length direction is sequentially distributed.
In one of the embodiments, referring to Fig. 3, a kind of tool as pattern detection structure provided by the utility model Body embodiment buffers and is equipped with water conservancy diversion microtrabeculae 312 at the entrance and exit of sap cavity 31, and the quantity of water conservancy diversion microtrabeculae 312 is multiple And be spaced apart, the effect of water conservancy diversion microtrabeculae 312 is to increase the homogeneity of liquid flowing, there is certain guiding to make liquid With.Water conservancy diversion microtrabeculae 312 can be cylindrical, and depth is less than or equal to the depth of buffering sap cavity 31.When water conservancy diversion microtrabeculae 312 is in circle When cylindricality, the ratio of the height of water conservancy diversion microtrabeculae 312 and its diameter in 1:1 between 1:5, the diameter of water conservancy diversion microtrabeculae 312 with it is adjacent Spacing ratio between water conservancy diversion microtrabeculae 312 in 1:0.5 between 1:1, the cross-sectional area of water conservancy diversion microtrabeculae 312 and buffering sap cavity 31 Area ratio is between 3% to 15%.More specifically, the width of the entrance and exit of buffering sap cavity 31 is respectively less than the width of central cavity Degree, first is that can guarantee the capacity of buffering sap cavity 31, second is that being more convenient for controlling flow.
Optionally, the outlet place of facing of overflow plate 3 and sample runner 401 offers sample inflow hole 3202, sample flow When entering the setting in hole 3202 so that sample flows to sample exit port, enter in fluid channel 32 by sample inflow hole 3202, then from Enter in test board 5 in the reaction mouth 3201 of 32 bottom of fluid channel.The width and depth one of sample runner 401 and fluid channel 32 Fixed, capacity is also certain, can accurately control the flow of sample, guarantee the accuracy of testing result.
In one of the embodiments, referring to Fig. 3, a kind of tool as pattern detection structure provided by the utility model Body embodiment, the depth of fluid channel 32 are less than the depth of buffering sap cavity 31, and the depth of fluid channel 32 is less than the depth of waste liquid chamber 33 Degree.In this way, Cai Huixiang fluid channel 32 flows when the buffer in buffering sap cavity 31 has a certain amount, rinse as much as possible micro- The side wall of runner 32, and the liquid in waste liquid chamber 33 will not guarantee the accuracy of testing result towards 32 adverse current of fluid channel.
In one of the embodiments, referring to Fig. 3, a kind of tool as pattern detection structure provided by the utility model Body embodiment, the inlet of fluid channel 32 are provided with the first choked flow boss 321, prevent liquid reflux in fluid channel 32 to slow In fliud flushing chamber 31, the first choked flow boss 321 can be positive arc-shaped or ellipse arc, and height is higher than the depth of fluid channel 32, First choked flow boss 321 is across the two sides of fluid channel 32, height and 32 whole height of fluid channel of the first choked flow boss 321 Ratio is between 5/10 to 9/10.The exit of fluid channel 32 is provided with the second choked flow boss 323, prevents in waste liquid chamber 33 Into fluid channel 32, the second choked flow boss 323 can be positive arc-shaped or ellipse arc liquid reflux, and height is higher than fluid channel 32 depth, the second choked flow boss 323 are also across the two sides of fluid channel 32, the height and fluid channel of the second choked flow boss 323 The ratio of 32 whole heights is between 5/10 to 9/10.
In one of the embodiments, referring to Fig. 3, a kind of tool as pattern detection structure provided by the utility model Body embodiment, is additionally provided with check (non-return) valve 322 between fluid channel 32 and buffer chamber 31, the width of check (non-return) valve 322 is less than fluid channel 32 width, so that the liquid in fluid channel 32 can not flow back.Optionally, the ratio of the width of check (non-return) valve and 32 width of fluid channel Between 1/12 to 6/12.Overflow plate 3 not only has check (non-return) valve 322 in one of the embodiments, but also has the first choked flow boss 321, the liquid in dual guarantee fluid channel 32 will not be back in buffering sap cavity 31.Certainly, in other embodiments, overflow plate 3 can also only include the first choked flow boss 321 or check (non-return) valve 322.
In one of the embodiments, referring to Fig. 4, a kind of specific reality as pattern detection structure provided by the invention Mode is applied, overflow plate 3 has the circumferential rib 34 for being located on reaction mouth 3201, circumferential rib 34 and test board 5 towards 5 side of test board It abuts against, the effect of circumferential rib 34 is: being abutted against with test board 5, liquid is made to enter the channel of test board 5 from reaction mouth 3201 Sealing, prevents buffer from leaking, and in assembly, does not need to melt connection overflow plate 3 and test board using chemical reagent such as glue 5, convenient disassembly.Specifically, the border of each reaction mouth 3201 is provided with a circumferential rib 34, alternatively, being arranged on overflow plate 3 There is a circumferential rib 34, which is centered around around all reaction mouths 3201.Optionally, the height and width of circumferential rib 34 The ratio of degree is in 1:1 between 1:5.The shape of circumferential rib 34 is not construed as limiting herein, can be around reaction mouth 3201.
Referring to Fig. 5, having sample runner 401 on filter plate 4, sample runner 401 can be S-shaped.Further, sample Runner 401 can be inverted structure, i.e. sample runner 401 is gradually increased from its entrance to the width of outlet, to increase haemocyte Sedimentation rate.Filter plate 4 is whole to be chosen as being made of transparent or translucent material material, is facilitated in observation filter plate 4 Situation.It in another embodiment, further include the storage being connected to runner referring to Fig. 6, filter plate 4a has sample runner 401a Chamber 402, convenient for storing the haemocyte etc. of residual packing.In another embodiment, referring to Fig. 7, filter plate 4b has sample flow Road 401b and sample runner 401c, sample runner 401b are identical with the entrance and exit of sample runner 401c, multiple sample runners 401 design can promote the efficiency and effect of sample dialysis.The structure and quantity of sample runner 401 herein without limitation, including It is not limited to above-mentioned three kinds of situations.Optionally, it is 40 μ l to 60 μ l that sample runner 401, which quantifies reservoir volume,.
Referring to Fig. 8, test board 5 include with the test section 51 that reacts 3201 face of mouth, the quantity of test section 51 with react The quantity of mouth 3201 is identical.Test board 5 further includes signal contact 52, and the bio signal after signal contact 52 will test is transformed into electricity Signal, and it is transmitted to external display lamp or display, to read testing result.
The utility model also provides a kind of biological detection platform, including the pattern detection structure in any of the above-described embodiment, It may also include upper cover plate and bottom plate etc., overflow plate 3, filter plate 4 and test board 5 are set between upper cover plate and bottom plate.
Biological detection platform provided by the utility model, overflow plate has buffer runner, mistake in pattern detection structure Filter plate has sample runner, and buffer can enter by buffer runner cleans test board in test board, sample can pass through sample Runner, which enters test board, to be tested, and buffer runner and sample runner are quantitative chamber, by by overflow plate and filter plate It is separately positioned, buffer and sample can be accurately controlled respectively into the flow in the pattern detection structure, improve fluid sample The accuracy of quantitative detection.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this Made any modifications, equivalent replacements, and improvements etc., should be included in the utility model within the spirit and principle of utility model Protection scope within.

Claims (10)

1. pattern detection structure characterized by comprising
Overflow plate offers buffer runner;
Filter plate, for filtering sample to be tested, the filter plate offers sample runner;
Test board, for testing sample to be tested, the test board is connected to the buffer runner, the sample runner.
2. pattern detection structure as described in claim 1, which is characterized in that the buffer runner include buffering sap cavity, with The fluid channel of the buffering sap cavity connection, the waste liquid chamber being connected to the fluid channel, the bottom wall of the fluid channel are offered for slow Fliud flushing flows into the reaction mouth of the test board.
3. pattern detection structure as claimed in claim 2, which is characterized in that the overflow plate has towards the test board side There is the circumferential rib for being located on the reaction mouth, the circumferential rib is abutted against with the test board.
4. pattern detection structure as claimed in claim 2, which is characterized in that the depth of the buffering sap cavity is greater than the miniflow The depth in road, the depth of the waste liquid chamber are greater than the depth of the fluid channel.
5. pattern detection structure as claimed in claim 2, which is characterized in that be equipped at the bottom wall of fluid channel entrance for preventing First choked flow boss of buffer reflux is equipped with the second choked flow for preventing waste reflux at the bottom wall of fluid channel outlet Boss.
6. pattern detection structure as claimed in claim 5, which is characterized in that the first choked flow boss and the fluid channel it Between be additionally provided with check (non-return) valve, the width of the check (non-return) valve is less than the width of the fluid channel.
7. pattern detection structure as claimed in claim 2, which is characterized in that the inlet and exit of the buffering sap cavity are equal Equipped with multiple water conservancy diversion microtrabeculaes being spaced apart from each other.
8. pattern detection structure as described in claim 1, which is characterized in that the filter plate, the test board are set to described The same side of overflow plate.
9. pattern detection structure as described in claim 1, which is characterized in that offered on the overflow plate and flow into institute for sample State the avoid holes of sample runner.
10. biological detection platform, which is characterized in that including the described in any item pattern detection structures of claim 1-9.
CN201822080580.6U 2018-12-11 2018-12-11 Pattern detection structure and biological detection platform Active CN209446355U (en)

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Application Number Priority Date Filing Date Title
CN201822080580.6U CN209446355U (en) 2018-12-11 2018-12-11 Pattern detection structure and biological detection platform

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Application Number Priority Date Filing Date Title
CN201822080580.6U CN209446355U (en) 2018-12-11 2018-12-11 Pattern detection structure and biological detection platform

Publications (1)

Publication Number Publication Date
CN209446355U true CN209446355U (en) 2019-09-27

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Effective date of registration: 20191108

Address after: J, building 6, No. 1288, Yecheng Road, Jiading District, Shanghai

Patentee after: Shanghai weiruibo Biotechnology Co., Ltd

Address before: Room 10, unit 111-113, floor 1, building 5, science and technology Avenue, Hong Kong Science Park, Shatin, Hong Kong, China

Patentee before: ABOT NANOBIOLOGICAL TECHNOLOGY CO., LTD.