CN209646519U - Micro-channel structure and biological detection platform - Google Patents
Micro-channel structure and biological detection platform Download PDFInfo
- Publication number
- CN209646519U CN209646519U CN201822085955.8U CN201822085955U CN209646519U CN 209646519 U CN209646519 U CN 209646519U CN 201822085955 U CN201822085955 U CN 201822085955U CN 209646519 U CN209646519 U CN 209646519U
- Authority
- CN
- China
- Prior art keywords
- fluid channel
- micro
- channel
- buffer
- depth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
It includes overflow plate that the utility model, which provides a kind of micro-channel structure and biological detection platform, the micro-channel structure, and overflow plate offers buffer runner, and buffer runner includes: buffering sap cavity, is flowed into for buffer；Fluid channel, for providing buffer, and the outlet with buffering sap cavity for component to be cleaned；Waste liquid chamber, is connected to fluid channel；Wherein, the depth of waste liquid chamber is greater than the depth of fluid channel.Micro-channel structure and biological detection platform provided by the utility model, the depth of waste liquid chamber is greater than the depth of fluid channel, in order to avoid the intracavitary waste reflux of waste liquid is into fluid channel, its structure is simple, waste reflux can be prevented by only needing the depth difference of setting fluid channel and waste liquid chamber, guarantee the accuracy of testing result.
Description
Technical field
The utility model belongs to biological monitor technical field, more specifically, be related to a kind of micro-channel structure and
Biological detection platform.
Background technique
In order to quickly screen illness, the diagnosis cause of disease, the reasons such as forensic identification, need using detecting instrument to blood, saliva,
The biological samples such as gastric juice are detected, and there is still a need for trained technicians for most quantitative testing in laboratory environments
It uses.Understand the physical condition of oneself in real time in order to facilitate patient, part detecting instrument has been reduced to make at home for patient
Portable detector.There is discardable module, i.e. disinfection abandons after a single use, can drop mould in portable detector
Block is internal usually to have fluid channel in order to guarantee quantitative detection, and sample to be tested and buffer flow into fluid channel first, then
Test module is flowed to, to control flow.But in actual use, the liquid in fluid channel is easy reflux, causes to detect
As a result inaccurate.
Utility model content
The purpose of this utility model is to provide a kind of micro-channel structures, to solve in fluid channel existing in the prior art
Liquid solution flow back caused by testing result inaccuracy technical problem.
In order to achieve the above purposes, the technical solution adopted by the utility model is: provides a kind of micro-channel structure, including overflow
Plate, the overflow plate offer buffer runner, and the buffer runner includes:
Sap cavity is buffered, is flowed into for buffer；
Fluid channel, for providing buffer, and the outlet with the buffering sap cavity for component to be cleaned；
Waste liquid chamber is connected to the fluid channel；
Wherein, the depth of the waste liquid chamber is greater than the depth of the fluid channel.
Further, the depth of the buffering sap cavity is greater than the depth of the fluid channel.
Further, the first choked flow boss for preventing buffer from flowing back is equipped at the bottom wall of the fluid channel entrance.
Further, the second choked flow boss for preventing waste reflux is equipped at the bottom wall of the fluid channel outlet.
Further, check (non-return) valve, the width of the check (non-return) valve are additionally provided between the first choked flow boss and the fluid channel
Degree is less than the width of the fluid channel.
Further, the inlet and exit of the buffering sap cavity are equipped with anti-blocking portion.
Further, the anti-blocking portion includes multiple water conservancy diversion microtrabeculaes being spaced apart from each other.
Further, the bottom wall of the fluid channel offers the reaction mouth that detection zone is flowed into for buffer.
Further, the overflow plate has the circumferential rib for preventing leakage, the ring backwards to the fluid channel side
Shape gilled rings is set to the border of the reaction mouth.
The utility model also provides a kind of biological detection platform, including above-mentioned micro-channel structure, further include with it is described micro-
Runner connection and the test board for detecting sample.
The beneficial effect of micro-channel structure provided by the utility model is: compared with prior art, the utility model is micro-
Buffer runner is offered on the overflow plate of flow passage structure, buffer runner includes buffering sap cavity, fluid channel and waste liquid chamber, buffering
Liquid in sap cavity rinses the component of the needs such as test board cleaning by fluid channel, and waste liquid back flows back into waste liquid chamber, wherein giving up
The depth of sap cavity is greater than the depth of fluid channel, in order to avoid the intracavitary waste reflux of waste liquid is into fluid channel, structure is simple, it is only necessary to set
The depth difference for setting fluid channel and waste liquid chamber can prevent waste reflux, guarantee the accuracy of testing result.
Detailed description of the invention
It, below will be to embodiment or the prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
Attached drawing needed in description is briefly described, it should be apparent that, the accompanying drawings in the following description is only that this is practical new
Some embodiments of type for those of ordinary skill in the art without any creative labor, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the structure chart one of micro-channel structure provided by the embodiment of the utility model；
Fig. 2 is the structure chart two of micro-channel structure provided by the embodiment of the utility model；
Fig. 3 is the partial enlarged view of A in Fig. 1；
Fig. 4 is the partial enlarged view of B in Fig. 1.
Wherein, each appended drawing reference in figure:
3- overflow plate；301- avoid holes；31- buffers sap cavity；311- propulsive liquid mouth；312- water conservancy diversion microtrabeculae；32- fluid channel；
3201- reacts mouth；3202- sample inflow hole；321- the first choked flow boss；322- check (non-return) valve；323- the second choked flow boss；33-
Waste liquid chamber；34- circumferential rib.
Specific embodiment
In order to which technical problem to be solved in the utility model, technical solution and beneficial effect is more clearly understood, with
Lower combination accompanying drawings and embodiments, the present invention will be further described in detail.It should be appreciated that specific reality described herein
It applies example to be only used to explain the utility model, is not used to limit the utility model.
It should be noted that it can be directly another when element is referred to as " being fixed on " or " being set to " another element
On one element or indirectly on another element.When an element is known as " being connected to " another element, it can
To be directly to another element or be indirectly connected on another element.
It is to be appreciated that term " length ", " width ", "upper", "lower", "front", "rear", "left", "right", "vertical",
The orientation or positional relationship of the instructions such as "horizontal", "top", "bottom" "inner", "outside" is that orientation based on the figure or position are closed
System, is merely for convenience of describing the present invention and simplifying the description, rather than the device or element of indication or suggestion meaning are necessary
It with specific orientation, is constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more of the features.The meaning of " plurality " is two or two in the description of the present invention,
More than, unless otherwise specifically defined.
It is existing referring to FIG. 1 to FIG. 4, that micro-channel structure provided by the utility model is illustrated.The micro-channel structure packet
Overflow plate 3 is included, buffer runner is offered on overflow plate 3, buffer runner includes buffering sap cavity 31, fluid channel 32 and waste liquid chamber
33.The top of overflow plate 3 is provided with upper cover plate, and upper cover plate is used to seal the top of buffer runner, becomes closed slow
Fliud flushing runner.It buffers sap cavity 31 to flow into for buffer, fluid channel 32 is used to control the flow of buffer or sample to be tested, waste liquid
Chamber 33 is for storing waste liquid, the outlet of fluid channel 32 and buffering sap cavity 31, the outlet of waste liquid chamber 33 and fluid channel 32.
In this way, as the liquid in buffering sap cavity 31 gradually increases, buffer enters fluid channel 32 after buffer enters buffering sap cavity 31
In, the buffer in fluid channel 32 flows into component to be cleaned, provides buffer for component to be cleaned, and the liquid after rinsing returns
Into waste liquid chamber 33.Wherein, the depth of waste liquid chamber 33 is greater than the depth of fluid channel 32, guarantees that the liquid in waste liquid chamber 33 will not return
It flow in fluid channel 32.More specifically, overflow plate 3 is horizontally disposed, the top of fluid channel 32 and waste liquid chamber 33 is in same level
On face, when the depth of waste liquid chamber 33 is greater than the depth of fluid channel 32, the bottom surface of waste liquid chamber 33 is lower than the bottom surface of fluid channel 32, makes to give up
The liquid stored in sap cavity 33 will not flow back.
Micro-channel structure provided by the utility model, compared with prior art, the overflow of the utility model micro-channel structure
Buffer runner is offered on plate 3, buffer runner includes buffering sap cavity 31, fluid channel 32 and waste liquid chamber 33, buffers sap cavity 31
In liquid the component of the needs cleaning such as test board is rinsed by fluid channel 32, waste liquid back flows back into waste liquid chamber 33, wherein giving up
The depth of sap cavity 33 is greater than the depth of fluid channel 32, in case the waste reflux in waste liquid chamber 33, into fluid channel 32, structure is simple
It is single, it is only necessary to which that the depth difference that fluid channel 32 and waste liquid chamber 33 is arranged can prevent waste reflux, guarantee the accuracy of testing result.
In one of the embodiments, referring to Fig. 1, one kind as micro-channel structure provided by the utility model is specific
Embodiment, the depth of fluid channel 32 are less than the depth of buffering sap cavity 31, and the bottom surface of buffering sap cavity 31 is lower than the bottom of fluid channel 32
Face, when so that buffer is full of buffering sap cavity 31, Cai Huixiang fluid channel 32 flows, its role is to: first is that rinsing as much as possible
The side wall of fluid channel 32 is convenient for quantitative detection second is that the flow of buffer can be precisely controlled.
Fig. 1 and Fig. 4 is please referred in one of the embodiments, one as micro-channel structure provided by the utility model
Specific embodiment is planted, the first choked flow boss 321 for preventing buffer from flowing back is equipped at the bottom wall of 32 entrance of fluid channel, the
One choked flow boss 321 can be positive the boss that arc-shaped, ellipse arc or corner are arc, and the first choked flow boss 321 is across
The two sides of fluid channel 32, height are greater than the depth of fluid channel 32, so that the top of the first choked flow boss 321 and fluid channel 32
The spacing on top is smaller, can not only prevent the liquid reflux in fluid channel 32, moreover it is possible to which accurate control enters in fluid channel 32
The flow of liquid.Optionally, the ratio of the height of the first choked flow boss 321 and 32 whole height of fluid channel 5/10 to 9/10 it
Between.
Fig. 1 and Fig. 3 is please referred in one of the embodiments, one as micro-channel structure provided by the utility model
Kind of specific embodiment, is equipped with the second choked flow boss 323 for preventing waste reflux at the bottom wall that fluid channel 32 exports, and second
Choked flow boss 323 can be positive the boss that arc-shaped, ellipse arc or corner are arc, and the second choked flow boss 323 is also across
The two sides of fluid channel 32, height are greater than the depth of fluid channel 32, so that the top of the second choked flow boss 323 and fluid channel 32
The spacing on top is smaller, can not only prevent the liquid reflux in waste liquid chamber 33, prevents in fluid channel 32 in the detection process
Sample enters in waste liquid chamber 33, accurate to control sample flow, moreover it is possible to which accurate control enters the flow of the liquid in waste liquid chamber 33, i.e.,
Accurately control flushing dose.Optionally, the ratio of the height of the second choked flow boss 323 and 32 whole height of fluid channel 5/10 to
Between 9/10.
Fig. 1 and Fig. 3 is please referred in one of the embodiments, one as micro-channel structure provided by the utility model
Kind specific embodiment, is additionally provided with check (non-return) valve 322, the width of check (non-return) valve 322 is small between the first choked flow boss 321 and fluid channel 32
In the width of fluid channel 32, so that the liquid in fluid channel 32 can not flow back.Optionally, the width of check (non-return) valve and fluid channel 32 are wide
The ratio of degree is between 1/12 to 6/12.Certainly, in other embodiments, overflow plate 3 can also only include the first choked flow boss 321
Or check (non-return) valve 322.
Fig. 1 and Fig. 4 is please referred in one of the embodiments, one as micro-channel structure provided by the utility model
Kind specific embodiment, the inlet and exit for buffering sap cavity 31 are equipped with anti-blocking portion 312.The effect in anti-blocking portion 312 is
The homogeneity for increasing liquid flowing has certain guiding role to liquid.More specifically, the entrance and exit of buffering sap cavity 31
Width be respectively less than the width of central cavity, first is that can guarantee buffer sap cavity 31 capacity, second is that being more convenient for controlling flow.
Fig. 1, Fig. 3 and Fig. 4 are please referred in one of the embodiments, as micro-channel structure provided by the utility model
A kind of specific embodiment, anti-blocking portion 312 include multiple water conservancy diversion microtrabeculaes being spaced apart from each other.Water conservancy diversion microtrabeculae can be cylindrical,
Height is less than or equal to the depth of buffering sap cavity 31.When water conservancy diversion microtrabeculae 312 is cylindrical, the height of water conservancy diversion microtrabeculae is straight with it
The ratio of diameter is in 1:1 between 1:5, and the spacing ratio between the diameter and adjacent guide microtrabeculae of water conservancy diversion microtrabeculae is in 1:0.5 to 1:1
Between, the cross-sectional area of water conservancy diversion microtrabeculae and the area ratio of buffering sap cavity 31 are between 3% to 15%.Liquid can from water conservancy diversion microtrabeculae it
Between gap flow through, change liquid buffering sap cavity 31 in original flow path, increase liquid flowing homogeneity.At other
In embodiment, it is possible to use the strainer with hole replaces water conservancy diversion microtrabeculae.
Fig. 1 and Fig. 4 is please referred to, as a kind of specific embodiment of micro-channel structure provided by the utility model, miniflow
The bottom wall in road 32 offers the reaction mouth 3201 that detection zone is flowed into for buffer.After buffer enters buffering sap cavity 31, flow into micro-
Runner 32 flows into test board 5 by reaction mouth 3201, flows into waste liquid chamber 33 after rinsing detection zone.Optionally, buffering sap cavity 31 enters
There is propulsive liquid mouth 311 compatible with buffer inlet 201 at mouthful, make to buffer the side wall of sap cavity 31 and the side wall of buffer inlet
It is tightly connected.Optionally, the quantity of reaction mouth 3201 is multiple, and the length direction along fluid channel 32 is sequentially distributed.Detection zone can
For the test board for detecting sample.
Optionally, the bottom wall of fluid channel 32 is also provided with sample inflow hole 3202, the setting of sample inflow hole 3202 so that
When sample flows to sample exit port, enter in fluid channel 32 by sample inflow hole 3202, then the reaction from 32 bottom of fluid channel
Enter in test board in mouth 3201.More specifically, sample inflow hole 3202 is set to the inlet of fluid channel 32.
Optionally, avoid holes 301 are also provided on overflow plate 3, avoid holes 301 and the entrance of sample face, and sample is worn
It crosses avoid holes to flow into the channel that other circulate for sample, for example, flowing into the filter plate for filtering sample, avoid holes 301
Effect be convenient for layout overflow plate 3 and filter plate etc..
In one of the embodiments, referring to Fig. 2, one kind as micro-channel structure provided by the utility model is specific
Embodiment, overflow plate 3 have the circumferential rib 34 for preventing leakage backwards to 31 side of fluid channel, and circumferential rib 34 is located on reaction
The border of mouth 3201.Circumferential rib 34 is abutted against with test board, and the effect of circumferential rib 34 is: being abutted against with test board, is made liquid
It is sealed from the channel that reaction mouth 3201 enters test board, prevents buffer from leaking, in assembly, do not need using chemistry such as glue
Reagent melts connection overflow plate 3 and test board, convenient disassembly.Specifically, the border of each reaction mouth 3201 is provided with one
Circumferential rib 34, alternatively, being provided with a circumferential rib 34 on overflow plate 3, which is centered around the week of all reaction mouths 3201
It encloses.Optionally, the ratio of the height of circumferential rib 34 and width is in 1:1 between 1:5.The shape of circumferential rib 34 does not limit herein
It is fixed, it can be around reaction mouth 3201.
The utility model also provides a kind of biological detection platform, including the micro-channel structure in any of the above-described embodiment, also
Including the test board for detecting sample, test board is connected to fluid channel 32.Specifically, the reaction mouth 3201 of fluid channel 32 and survey
Test plate (panel) faces, and liquid is flowed into test board by reaction mouth 3201.The biological detection platform further includes being covered on overflow plate 3
Upper cover plate, upper cover plate seals the top of buffer runner.
Biological detection platform provided by the utility model offers buffer runner on the overflow plate 3 of micro-channel structure,
Buffer runner includes buffering sap cavity 31, fluid channel 32 and waste liquid chamber 33, and the liquid buffered in sap cavity 31 is rushed by fluid channel 32
The component of the needs such as test board cleaning is washed, waste liquid back flows back into waste liquid chamber 33, and wherein the depth of waste liquid chamber 33 is greater than fluid channel
32 depth, in order to avoid the waste reflux in waste liquid chamber 33 is into fluid channel 32, structure is simple, it is only necessary to fluid channel 32 be arranged and give up
The depth difference of sap cavity 33 can prevent waste reflux, guarantee the accuracy of testing result.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
Made any modifications, equivalent replacements, and improvements etc., should be included in the utility model within the spirit and principle of utility model
Protection scope within.
Claims (10)
1. micro-channel structure, which is characterized in that including overflow plate, the overflow plate offers buffer runner, the buffer
Runner includes:
Sap cavity is buffered, is flowed into for buffer；
Fluid channel, for providing buffer, and the outlet with the buffering sap cavity for component to be cleaned；
Waste liquid chamber is connected to the fluid channel；
Wherein, the depth of the waste liquid chamber is greater than the depth of the fluid channel.
2. micro-channel structure as described in claim 1, which is characterized in that the depth of the buffering sap cavity is greater than the fluid channel
Depth.
3. micro-channel structure as described in claim 1, which is characterized in that be equipped at the bottom wall of the fluid channel entrance for preventing
Only the first choked flow boss of buffer reflux.
4. micro-channel structure as described in claim 1, which is characterized in that be equipped at the bottom wall of the fluid channel outlet for preventing
Only the second choked flow boss of waste reflux.
5. micro-channel structure as claimed in claim 3, which is characterized in that between the first choked flow boss and the fluid channel
It is additionally provided with check (non-return) valve, the width of the check (non-return) valve is less than the width of the fluid channel.
6. micro-channel structure as described in claim 1, which is characterized in that the inlet and exit of the buffering sap cavity are all provided with
There is anti-blocking portion.
7. micro-channel structure as claimed in claim 6, which is characterized in that the anti-blocking portion includes multiple water conservancy diversion being spaced apart from each other
Microtrabeculae.
8. micro-channel structure as described in claim 1, which is characterized in that the bottom wall of the fluid channel is offered for buffering liquid stream
Enter the reaction mouth of detection zone.
9. micro-channel structure as claimed in claim 8, which is characterized in that the overflow plate has backwards to the fluid channel side
For preventing the circumferential rib of leakage, the circumferential rib is located on the border of the reaction mouth.
10. biological detection platform, which is characterized in that including the described in any item micro-channel structures of claim 1-9, further include with
The fluid channel connection and the test board for detecting sample.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822085955.8U CN209646519U (en) | 2018-12-11 | 2018-12-11 | Micro-channel structure and biological detection platform |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822085955.8U CN209646519U (en) | 2018-12-11 | 2018-12-11 | Micro-channel structure and biological detection platform |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209646519U true CN209646519U (en) | 2019-11-19 |
Family
ID=68507731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201822085955.8U Active CN209646519U (en) | 2018-12-11 | 2018-12-11 | Micro-channel structure and biological detection platform |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209646519U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939752A (en) * | 2018-12-11 | 2019-06-28 | 安博特纳米生物科技有限公司 | Micro-channel structure and biological detection platform |
-
2018
- 2018-12-11 CN CN201822085955.8U patent/CN209646519U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939752A (en) * | 2018-12-11 | 2019-06-28 | 安博特纳米生物科技有限公司 | Micro-channel structure and biological detection platform |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101262950B (en) | A flow metered analyzer | |
| US3345910A (en) | Colorimeter flow cell | |
| KR20110084240A (en) | Disposable cassette and method of use for blood analysis on blood analyzer | |
| JP5506440B2 (en) | Liquid sample quantifier | |
| CN208224274U (en) | A kind of micro-fluidic chip and the analysis instrument with the micro-fluidic chip | |
| WO2010032804A1 (en) | Analysis device and analysis method | |
| KR102481408B1 (en) | Multiple-use sensor assembly for body fluids | |
| CN209646519U (en) | Micro-channel structure and biological detection platform | |
| JPH03257366A (en) | Blood circuit and blood measuring apparatus and method | |
| US3867042A (en) | Cuvette construction | |
| CN105921185A (en) | Urine multi-index detection microfluidic device and preparation method thereof | |
| CN109939752A (en) | Micro-channel structure and biological detection platform | |
| CN209446355U (en) | Pattern detection structure and biological detection platform | |
| CN209680120U (en) | Biological detection platform | |
| JP6130788B2 (en) | Sample injection apparatus for biochemical analysis, flow-type biochemical analysis apparatus, and hemoglobin component measurement method | |
| US20220280937A1 (en) | Arrangement for analyzing a liquid sample | |
| CN205879767U (en) | Liquid analysis slide glass | |
| ES2910048T3 (en) | Provision for the individualized blood test of a patient and its use | |
| JP3814559B2 (en) | Endotoxin concentration measuring device | |
| CN107449712B (en) | Method and device for detecting reagent in channel and cell analyzer system | |
| CN207198160U (en) | A kind of carrier for preventing detection reagent bar mighty torrent | |
| CN206387811U (en) | The device of analyte in a kind of detection sample | |
| CN211424010U (en) | Multi-range water quality analyzer flow path system | |
| CN109967138A (en) | Biological detection platform | |
| SE503669C2 (en) | Procedure for analysis and apparatus for carrying out the procedure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |