CN209205052U - A kind of blood leucocyte-removing filter device - Google Patents
A kind of blood leucocyte-removing filter device Download PDFInfo
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- CN209205052U CN209205052U CN201821822292.7U CN201821822292U CN209205052U CN 209205052 U CN209205052 U CN 209205052U CN 201821822292 U CN201821822292 U CN 201821822292U CN 209205052 U CN209205052 U CN 209205052U
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Abstract
The utility model discloses a kind of blood leucocyte-removing filter device, including two panels outer layer flexible packaging film and stripper loop, closed filter core is provided between the two panels outer layer flexible packaging film；The filter core includes two layers of filter membrane, support tube and the fixed film of two panels internal layer for being respectively provided at two layers of filter membrane edge, and one end of the stripper loop is fixed on filter core top, and the other end is placed between two layers of filter membrane, thus sap cavity after forming sap cavity before filter, center sap cavity and filtering；The fixed film of the internal layer, stripper loop, filter membrane and support tube form closed filter core by high frequency welding；The edge seal of the filter core and outer layer flexible packaging film assembles；Sap cavity offers inlet ducts before the filter, and sap cavity offers delivery channel after the filter.Blood leucocyte-removing filter device provided by the utility model, velocity of blood flow is fast but does not influence leukocyte removal efficiency, has many advantages, such as high pressure resistant steam sterilizing, side leakage free, the blood constituent rate of recovery is high.
Description
Technical field
The utility model relates to a kind of medical filter tool more particularly to a kind of blood leucocyte-removing filter devices.
Background technique
Leucocyte is the important component of human body natural's system of defense, but when it is transfused in company with blood constituent allosome
It can produce many harmful adverse reactions, such as: nonhemolytic febrific reaction (FNHTR), Inefficacy of Platelets Transfusion (PTR), blood transfusion
Graft versus host disease(GVH disease) (GVHD) and the correlated virus (CMV, HTLV-I/II, HIV) etc. of leucocyte carrying may be propagated afterwards.
Therefore, remaining leucocyte is considered as a kind of pollutant in blood and blood constituent, should be removed；This is defeated to clinical safety
Blood reduces blood transfusion risk and has great importance.In order to reduce blood transfusion risk, transfusion safety is improved, is occurred a variety of for going
Except the filter device of leucocyte in blood and blood constituent.Two classes are broadly divided into, one kind is hard filter housing filter device, another
For soft filter device.The former cannot carry out low-temperature and high-speed centrifugation together with plastic blood bag using the shell of ABS, PC injection molding to divide
It from blood constituent, is centrifuged again due to can only first filter, so fresh plasma cannot be obtained using above there is certain limitation
And platelets by manual collection.And flexible packing material is used, high speed centrifugation can be carried out together with plastic blood bag, obtain fresh plasma and blood
A variety of blood constituents such as platelet.Therefore soft leucocyte-removing filter device is more and more applied.
American documentation literature US2003/0150793A1 discloses a kind of flexible package filter device, the structure used for before filtering and
Filter latter two chamber.A kind of leucocyte-removing filter device disclosed in Chinese patent literature CN200810015729.0, using soft knot
Structure bag body is fixed in soft bag body by inner support, forms before filter and filter latter two chamber, and blood is separated with blood after filter before filtering
It opens.Chinese patent literature CN201220471656.8 discloses a kind of soft shell filter for removing white blood cell, including two panels PVC outer membrane and
Filter membrane component, the filter membrane component are located between two panels PVC outer membrane, sap cavity after forming sap cavity before filtering and filtering, and after filter at sap cavity
Equipped with annular brace pipe.But the problem of above-mentioned design maximum is: will block filter membrane when occurring grumeleuse or micro- aggressiveness in blood, and lead
It causes blood that cannot filter completely, needs to re-replace filter device or go white blood ingredient to use as non-.Chinese patent text
The shortcomings that offering the Soft Roll fixed filter that CN201220471656.8 is related to is the heat seal welding of filter material and filter membrane, and there are more polygon
Edge causes blood outlet flow unsmooth, and then keeps blood residence time inside filter too long, causes to waste, while to blood
Quality affects.There are enough liquid out for the flexible package filter that Chinese patent literature CN200820153904.8 is related to
Channel, but filter material is superimposed, and is unfavorable for the complicated blood situation of reply, thus have much room for improvement.
Utility model content
The technical problem to be solved by the utility model is to provide a kind of blood leucocyte-removing filter device, velocity of blood flow is fast
But leukocyte removal efficiency is not influenced, has many advantages, such as high pressure resistant steam sterilizing, side leakage free, the blood constituent rate of recovery is high.
The utility model is to solve above-mentioned technical problem and the technical solution adopted is that provide a kind of blood leucocyte-removing mistake
Device, including two panels outer layer flexible packaging film and stripper loop are filtered, is provided with closed filter core between the two panels outer layer flexible packaging film；
The filter core includes two layers of filter membrane, support tube and the fixed film of two panels internal layer for being respectively provided at two layers of filter membrane edge, the stripper loop
One end be fixed on filter core top, the other end is placed between two layers of filter membrane, thus formed filter before sap cavity, center sap cavity and filter after liquid
Chamber；The fixed film of the internal layer, stripper loop, filter membrane and support tube form closed filter core by high frequency welding；The filter core and outer
The edge seal assembling of layer flexible packaging film；Sap cavity offers inlet ducts before the filter, and sap cavity offers outlet guide after the filter
Pipe.
Above-mentioned blood leucocyte-removing filter device, wherein the filter core by sandwich stripper loop two layers of filter membrane, branch
The fixed film periphery hot melt of stay tube and internal layer is made, and by two layers of complete heat seal in filter membrane edge.
Above-mentioned blood leucocyte-removing filter device, wherein the filter membrane includes coarse filtration layer filter membrane and filter bed of essence filter membrane, institute
It states stripper loop to be placed among coarse filtration layer filter membrane and filter bed of essence filter membrane, and coarse filtration layer filter membrane and filter bed of essence filter membrane is formed separately
Heart sap cavity；Form sap cavity before filtering between the fixed film of the coarse filtration layer filter membrane and a piece of internal layer, the filter bed of essence filter membrane with another
Sap cavity after filter is formed between the fixed film of internal layer.
Above-mentioned blood leucocyte-removing filter device, wherein the support tube is placed on filter bed of essence filter membrane and internal layer is fixed
Among film, and it is connected together by hot melting way.
Above-mentioned blood leucocyte-removing filter device, wherein be equipped with and reinforce at the hot melt of the filter membrane and the fixed film of internal layer
Site, the reinforcement site are made of the discontinuous groove that hot pressing is formed.
Above-mentioned blood leucocyte-removing filter device, wherein the stripper loop by soft medical PVC conduit thermal synthesis ring,
The fixed film of the internal layer and outer layer flexible packaging film use medical PVC film；The support tube, inlet ducts and delivery channel are adopted
With medical PVC material.
Above-mentioned blood leucocyte-removing filter device, wherein the material of the coarse filtration layer filter membrane and filter bed of essence filter membrane is not
With the ultra-fine polyester non-woven fabric filtering material in aperture.
Above-mentioned blood leucocyte-removing filter device, wherein the coarse filtration layer filter membrane is 1~6 layer, and every layer with a thickness of 0.5
~2mm, maximum diameter of hole are 20~150 μm；The filter bed of essence filter membrane is 2~14 layers, and every layer with a thickness of 0.5~2mm, maximum diameter of hole
It is 12~21 μm.
The utility model comparison prior art has following the utility model has the advantages that blood leucocyte-removing mistake provided by the utility model
Filter device, using soft sheathing material and filter membrane, heat position be resistant in high temperature and high pressure steam sterilization process and
It does not rupture, edge is without leaking hunting when blood filtration；Suitable for filter out whole blood, red cell suspension, blood plasma, 99% or more blood platelet
Leucocyte；Easy to use, stock utilization is high, copes with complicated blood situation, goes white effect good and batch easy to accomplish
Production.
Detailed description of the invention
Fig. 1 is the utility model blood leucocyte-removing filter device the schematic diagram of the section structure；
Fig. 2 is the utility model blood leucocyte-removing filter device structural schematic diagram.
In figure:
1 inlet ducts, 2 outer layer flexible packaging film, 3 support tube
4 stripper loop, 5 filter core 6 reinforces site
7 delivery channel, 8 internal layer stent 9-1 coarse filtration layer filter membrane
11 center sap cavity of sap cavity before 9-2 filter bed of essence filter membrane 10 is filtered
Sap cavity after 12 filters
Specific embodiment
The utility model will be further described with reference to the accompanying drawings and examples.
Fig. 1 is the utility model blood leucocyte-removing filter device structural schematic diagram；Fig. 2 goes white for the utility model blood
Cell filtering device the schematic diagram of the section structure.
Referring to Figure 1 and Fig. 2, blood leucocyte-removing filter device provided by the utility model, including it is inlet ducts 1, outer
Layer flexible packaging film 2, stripper loop 4, filter core 5 and delivery channel 7 form.The filter core 5 is by coarse filtration layer filter membrane 9-1, stripper loop 4, essence
The fixed film 8 of filtering layer filter membrane 9-2, support tube 3 and internal layer is integrated by hot melting way.
The inlet ducts 1, delivery channel 7, filter core 5 and outer layer flexible packaging film 2 heat closely sealed edge by high frequency processing
Blood leucocyte-removing filter device is made.
The stripper loop 4 is built among filter core 5, and stripper loop 4 is an elliptical annular body, the upper end and 5 top of filter core
Position is fixed through heat seal, and lower end is placed on 5 bottom of filter core, and coarse filtration layer filter membrane 9-1 and filter bed of essence filter membrane 9-2 are separated, and is formed
Center sap cavity 11 makes blood after the filtering of coarse filtration layer, slightly stops into the sap cavity and flow into filter bed of essence again.Purpose is to make blood
Micro- aggressiveness and blood clot in liquid etc. are stopped in coarse filtration layer, and guarantee is smooth by the blood filtration of filter bed of essence, reduce blocking, are improved
The rate of filtration and do not influence filter effect.
The support tube 3 is placed among filter bed of essence filter membrane 9-2 and the fixed film 8 of internal layer, and one hot melt is fixed, it is therefore intended that anti-
Only filter bed of essence filter membrane 9-2 is adhered on the fixed film 8 of internal layer, is conducive to blood and is flowed out.Due to the presence of support tube 3, after maintaining filter
The smooth outflow of blood improves the rate of filtration, reduces the loss of blood after filter.
The fixed film 8 of the internal layer of the filter core 5 of the utility model filter device and the outer layer flexible packaging film 2 of 5 two sides of filter core pass through
After high frequency heat seal, sap cavity 10 before filtering is formed between outer layer flexible packaging film 2 and the coarse filtration layer filter membrane 9-1 of filter core 5, in outer layer Soft Roll
Fill sap cavity 12 after forming filter between film 2 and the filter bed of essence filter membrane 9-2 of filter core 5.The inlet ducts 1 are placed on outer layer flexible packaging film
Between 2 and the fixed film 8 of internal layer of coarse filtration layer side, it is fixed in the preceding sap cavity 10 of filter by high frequency heat seal；The other end connects with blood bag,
Guarantee that blood is flowed into the preceding sap cavity 10 of filter by inlet ducts before filtering.Described 7 one end of delivery channel is placed on outer layer flexible package
Between film 2 and the fixed film 8 of the internal layer of filter bed of essence side, it is fixed on by high frequency heat seal after filtering 12 in sap cavity；The other end and collecting bag
It is connected, guarantees to go white blood to flow into collecting bag in sap cavity 12 after filtering.Edge is heated in the fixed film 8 of the internal layer of filter core 5
Have and reinforce site 6, for the discontinuous groove that hot pressing mode is formed, guarantees the stability of hot melt zone, prevent side leakage and blood stream
Out.
The blood leucocyte-removing filter device of the utility model filters preceding sap cavity in use, blood enters by inlet ducts 1
10, through coarse filtration layer filter membrane 9-1 coarse filtration, into center sap cavity 11, while by micro- aggressiveness, the blood clot etc. in cell fragment, blood
It intercepts；Blood again can be quickly through through filter bed of essence filter membrane 9-2 filter layer, and removes leucocyte therein, enters liquid after filter
In chamber 12, flowed out in collecting bag by delivery channel 7.
The filter membrane material of the blood leucocyte-removing filter device of the utility model is the ultra-fine polyester non-woven fabric of different pore size
Filtering material or other filtering materials, it is preferred that, coarse filtration layer filter membrane 9-1 constitutes every thickness degree by 1~6 layer of filtering material
For 0.5~2mm, maximum diameter of hole is 20~150 μm；Filter bed of essence filter membrane 9-2 is made of 2~14 layers of filtering material, every layer with a thickness of
0.5~2mm, maximum diameter of hole are 12~21 μm.Inlet ducts 1, delivery channel 7 are all made of soft medical PVC material；It is whole soft
It is soft, anti-extrusion, high temperature high voltage resistant steam sterilizing.
The blood leucocyte-removing filter device of the utility model can pass through inlet ducts 1 and delivery channel 7 and outer order blood
Bag or multi-linked blood bag integrally sterilize after being connected, and can be subjected to 50kPa atmospheric pressure 2min after high temperature and high pressure steam sterilizing and not occur
Gas leakage.
Utility model device can be connected in different blood bag systems according to the demand of clinical use, including
Single blood bag and multi-linked blood bag system, for removing in a variety of blood such as whole blood, red suspension, blood plasma, blood platelet and blood constituent
Leucocyte can be effectively improved the rate of filtration of blood, guarantee leucocyte removal effect, improve Blood calldack rate, provide safe
Blood and blood constituent have biggish clinical value for clinical use.
Although the utility model is disclosed as above with preferred embodiment, so it is not intended to limit the utility model, any
Those skilled in the art, without departing from the spirit and scope of the utility model, when can make a little modification and it is perfect, therefore this
The protection scope of utility model, which is worked as, to be subjected to the definition of the claims.
Claims (8)
1. a kind of blood leucocyte-removing filter device, which is characterized in that including two panels outer layer flexible packaging film (2) and stripper loop (4),
Closed filter core (5) are provided between the two panels outer layer flexible packaging film (2)；The filter core (5) includes two layers of filter membrane, support tube
(3) and be respectively provided at two layers of filter membrane edge two panels internal layer it is fixed film (8), one end of the stripper loop (4) is fixed on filter core (5)
Top, the other end are placed between two layers of filter membrane, thus sap cavity (12) after forming sap cavity (10) before filter, center sap cavity (11) and filtering；
The internal layer fixed film (8), stripper loop (4), filter membrane and support tube (3) form closed filter core (5) by high frequency welding；It is described
Filter core (5) and the edge seal of outer layer flexible packaging film (2) assemble；Sap cavity (10) offers inlet ducts (1) before the filter, described
Sap cavity (12) offers delivery channel (7) after filter.
2. blood leucocyte-removing filter device as described in claim 1, which is characterized in that the filter core (5) is by sandwich
Fixed film (8) the periphery hot melt of two layers of filter membrane, support tube (3) and the internal layer of stripper loop (4) is made, and two layers of filter membrane edge is complete
Heat seal.
3. blood leucocyte-removing filter device as described in claim 1, which is characterized in that the filter membrane includes coarse filtration layer filter membrane
(9-1) and filter bed of essence filter membrane (9-2), the stripper loop (4) are placed in coarse filtration layer filter membrane (9-1) and filter bed of essence filter membrane (9-2)
Between, and coarse filtration layer filter membrane (9-1) and filter bed of essence filter membrane (9-2) are formed separately center sap cavity (11)；The coarse filtration layer filter membrane (9-
1) sap cavity (10) before filtering is formed between a piece of internal layer fixed film (8), the filter bed of essence filter membrane (9-2) is fixed with another internal layer
Sap cavity (12) after filtering is formed between film (8).
4. blood leucocyte-removing filter device as claimed in claim 3, which is characterized in that the support tube (3) is placed on essence
Filtering layer filter membrane (9-2) and internal layer fixed film (8) are intermediate, and are connected together by hot melting way.
5. blood leucocyte-removing filter device as described in claim 1, which is characterized in that the filter membrane and the fixed film of internal layer
(8) it is equipped at hot melt and reinforces site (6), reinforcement site (6) is made of the discontinuous groove that hot pressing is formed.
6. blood leucocyte-removing filter device as described in claim 1, which is characterized in that the stripper loop (4) is by soft doctor
With PVC conduit thermal synthesis ring, the internal layer fixed film (8) and outer layer flexible packaging film (2) use medical PVC film；The support
Pipe (3), inlet ducts (1) and delivery channel (7) are all made of medical PVC material.
7. blood leucocyte-removing filter device as claimed in claim 3, which is characterized in that the coarse filtration layer filter membrane (9-1) and
The material of filter bed of essence filter membrane (9-2) is the ultra-fine polyester non-woven fabric filtering material of different pore size.
8. blood leucocyte-removing filter device as claimed in claim 7, which is characterized in that the coarse filtration layer filter membrane is 1~6
Layer, every layer with a thickness of 0.5~2mm, maximum diameter of hole is 20~150 μm；The filter bed of essence filter membrane be 2~14 layers, every layer with a thickness of
0.5~2mm, maximum diameter of hole are 12~21 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821822292.7U CN209205052U (en) | 2018-11-05 | 2018-11-05 | A kind of blood leucocyte-removing filter device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821822292.7U CN209205052U (en) | 2018-11-05 | 2018-11-05 | A kind of blood leucocyte-removing filter device |
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| Publication Number | Publication Date |
|---|---|
| CN209205052U true CN209205052U (en) | 2019-08-06 |
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| CN201821822292.7U Active CN209205052U (en) | 2018-11-05 | 2018-11-05 | A kind of blood leucocyte-removing filter device |
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- 2018-11-05 CN CN201821822292.7U patent/CN209205052U/en active Active
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