CN202366236U - Nucleated cell purifier - Google Patents

Nucleated cell purifier Download PDF

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Publication number
CN202366236U
CN202366236U CN2011204722672U CN201120472267U CN202366236U CN 202366236 U CN202366236 U CN 202366236U CN 2011204722672 U CN2011204722672 U CN 2011204722672U CN 201120472267 U CN201120472267 U CN 201120472267U CN 202366236 U CN202366236 U CN 202366236U
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CN
China
Prior art keywords
blood
depurator
nucleated cell
blood vessel
lower cover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2011204722672U
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Chinese (zh)
Inventor
刘进
杜磊
丁五行
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saipuruite Blood Technology Beijing Co ltd
West China Hospital of Sichuan University
Original Assignee
Saipuruite Blood Technology Beijing Co ltd
West China Hospital of Sichuan University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saipuruite Blood Technology Beijing Co ltd, West China Hospital of Sichuan University filed Critical Saipuruite Blood Technology Beijing Co ltd
Priority to CN2011204722672U priority Critical patent/CN202366236U/en
Application granted granted Critical
Publication of CN202366236U publication Critical patent/CN202366236U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model provides a nucleated cell purifier, which comprises an upper cover, a lower cover and a filter film, wherein the upper cover is communicated with a blood inlet pipe, the lower cover is communicated with a blood outlet pipe, the filter film is fixed between the upper cover and the lower cover, the upper cover and the lower cover are closely combined by welding, the filter film is acetate non-woven fabrics, the aperture of the acetate non-woven fabrics is 7-20 micrometer, the lower end of the nucleated cell purifier is provided with a Murphy's tube for transfusing blood, the upper cover of the nucleated cell purifier is provided with a plurality of blood guide slots crossly arranged or is provided with a structure similar to a shower head for bathing, and blood can be split by the structure to flow over the filter film, thereby leading the filter film to be fully used in various directions. The blood inlet pipe is provided with a needle head interface or a screw interface to be inserted into a blood recycle bag and connected with the blood recycle bag. The nucleated cell purifier can further filter dropping fibers of the filter film in the blood, and furthest reduces air pollution. The nucleated cell purifier can remove all nucleated cells comprising tumor cells in the blood, furthest protects number and function of red blood cells, and guarantees quality of recycled blood.

Description

The nucleated cell depurator
Technical field
This utility model relates to a kind of blood filter, is specifically related to a kind of blood nucleated cell and purifies filter.
Background technology
The autoblood recovery has not been a new noun concerning much human in the art; It mainly mixes autoblood in the suction storage blood jar through vacuum suction with a certain amount of heparin; Concentrate in the container handling (Centrifuge Cup) erythrocyte is centrifugal through high speed centrifugation, lighter material (blood plasma, thrombin, flushing liquor, free hemoglobin, cell debris) then overflows from container handling and enters in the waste fluid bag.When being full of erythrocyte in the container handling, injecting normal saline and clean.Cell is by the normal saline clean, and leukocyte, platelet, free hemoglobin etc. are diluted repeatedly and discharge, and stop centrifugal treating, and the erythrocyte after the washing is pumped to and has promptly accomplished autohemic recovery in the transfusion bags.Above-mentioned whole process can realize through blood recovery system, in operation, is widely used.
Autoblood reclaims and to have significant superiority in the art, shows: 1. for patient has practiced thrift spending, and the patients that transfuse blood in a large number of the more need of amount of bleeding especially; 2. solved in the art trouble and worry for the patient of special blood group (is the negative patient of Rh like blood group) with blood; 3. significantly reduced the generation of the various infectious diseases of propagating through the allosome blood transfusion, like hepatitis B, AIDS etc.; 4. significantly reduced because of the anaphylactoid generation due to the allosome blood transfusion; 5. practice thrift the blood source, that reduces that blood bank faces uses blood pressure power.
But autoblood reclaims the contraindication that it is also arranged in the art, because of blood recovery system does not possess the function of sterilizing and removing tumor cell, so the blood of open injury and tumour patient can not reclaim, spreads with systemic infection and the tumor that prevents to cause because of septicemia.In addition, erythrocyte number and the function through the normal saline washing all has very macrolesion.How can in art, guarantee to reclaim the safety of blood in the autoblood recovery, and protect erythrocytic quantity of institute's washed blood and function to greatest extent, to reclaim quality to reach best blood, be the continuous problem of exploring of scholars of this area always.
Utility model patent ZL200910210857.5 discloses a kind of safe, reliable and strong disposable use tumor cell filter of clinical practice property, and tumor cell can not be survived in the filtering blood of this cell filter.But this cell filter in use, and filtering blood exists and to be filtered the film safety hidden danger such as fiber contamination and air pollution that come off.
Summary of the invention
In view of this, in order to overcome the deficiency of prior art, this utility model provides in a kind of further filtering blood the filter membrane fiber that comes off, and reduces air pollution nucleated cell depurator to greatest extent.
The nucleated cell depurator that this utility model provides; Said depurator comprise the loam cake that is communicated with blood vessel, be communicated with the lower cover of blood vessel and be fixed on loam cake and lower cover between filter membrane, combine closely through welding between said loam cake and lower cover, said filter membrane is the acetate non-woven fabrics of aperture 7-20 μ m; Saidly enter the center that blood vessel is positioned at loam cake; Go out the center that blood vessel is positioned at lower cover, said nucleated cell depurator is a flat, and said depurator lower end is provided with blood transfusion and uses Murphy tube.
The filter membrane aperture is 20-40 μ m in the Murphy tube, can the fiber filter that comes off in the blood after the acetate non-woven fabrics filters be fallen.
Further, on the said depurator upper and lower cover inwall several crisscross blood guide channels are set all.
Groove in the said blood guiding groove can guide blood scatter and flows through filter membrane, and the filter membrane all directions can both be fully used.
Further, said depurator loam cake is by inside and outside two-layer the composition, and internal layer is offered homodisperse aperture, and the cavity of inside and outside two interlayers communicates with the dispersion apertures of advancing on blood vessel and the internal layer of outer center.
Said depurator loam cake is similar has a bath with the structure of shower head, blood is scatter flow through filter membrane, and the filter membrane all directions can both be fully used.
Further, saidly advance blood vessel and steam vent is set near the position of nucleated cell depurator.
Because this steam vent is away from filter membrane, it is cleaner to be arranged on the steam vent that covers in the purification, is difficult for being polluted by outside air.
Further, saidly advance blood vessel and needle hub is set inserts in the blood reclaiming bag and be connected with the blood reclaiming bag.
Guarantee the sterile working, prevent blood contamination in the operating process.
Further, saidly advance blood vessel the screw socket interface is set, said screw socket interface is connected with the blood reclaiming bag through inserting in blood reclaiming bag with its screw socket progressive joint that is complementary.
In the same assurance sterile working process, blood is not contaminated.
Further, said with advance the blood reclaiming bag that blood vessel is connected and be provided with containing mark, every 12-200cm 2Filter membrane disposable filtering blood volume 200-1200ml is preferably 400-1200ml.
When tumor operation blood reclaims, for the blood flow volume of avoiding purifying surpasses the depurator working range, the special blood reclaiming bag that is complementary with it according to its working range design, and on bag, be carved with scale.
The beneficial effect of this utility model is:
This utility model is the filter membrane fiber that comes off in the filtering blood fully, and reduces the pollution of blood in sterile working's process to greatest extent.With the washing of MAP liquid it being soaked into the back uses; No matter whether contain tumor cell in the filtering blood; This filter all can with all nucleated cell or filter out or destruction; Cause through no longer containing active nucleated cell in the blood of filter, yet to there not being nuclear erythrocyte but not have destruction.Be applicable to that blood reclaims in tumor patient and the non-tumor patient art, the filtration of storehouse blood.
Description of drawings
Fig. 1 is this utility model nucleated cell depurator (lower end is provided with blood transfusion and uses Murphy tube) structural representation;
Fig. 2 is provided with the upper and lower cover of several crisscross blood guide channels for this utility model nucleated cell depurator;
Fig. 3 has a bath with the structural representation of shower head for this utility model depurator loam cake is similar;
Fig. 4 advances blood vessel and near the position of nucleated cell depurator the steam vent sketch map is set for this utility model is said;
Fig. 5 is provided with the sketch map that is connected with the blood reclaiming bag in the needle hub insertion blood reclaiming bag for this utility model advances blood vessel;
Fig. 6 advances the screw socket interface sketch map that blood vessel is provided with for said;
Fig. 7 is that said screw socket interface is through inserting the sketch map that is connected with the blood reclaiming bag in blood reclaiming bag with its screw socket progressive joint that is complementary.
Wherein: 1-Murphy tube (interior band filter membrane), the blood guiding groove that 2-is crisscross, the 3-filter membrane, 4-is similar to have a bath with the depurator loam cake of shower head structure; 5-blood reclaiming bag, 6-steam vent, 7-nucleated cell depurator; The 8-syringe needle, 9-screw socket, 10-screw socket interface.
The specific embodiment
Below will be with reference to accompanying drawing, the preferred embodiment of this utility model is carried out detailed description, preferred embodiment has been merely explanation this utility model, rather than in order to limit the protection domain of this utility model.
Embodiment 1
A kind of nucleated cell depurator of this utility model; Said depurator comprise the loam cake that is communicated with blood vessel, be communicated with the lower cover of blood vessel and be fixed on loam cake and lower cover between filter membrane 3, combine closely through welding between said loam cake and lower cover, said filter membrane is the acetate non-woven fabrics of aperture 7-20 μ m; Saidly enter the center that blood vessel is positioned at loam cake; Go out the center that blood vessel is positioned at lower cover, said nucleated cell depurator is a flat, and said depurator 7 lower ends are provided with blood transfusion with Murphy tube 1.
Several crisscross blood guide channels 2 all are set on the said depurator upper and lower cover inwall.
Said depurator loam cake is by inside and outside two-layer the composition, and internal layer is offered homodisperse aperture, and the cavity of inside and outside two interlayers communicates with several dispersion apertures of advancing on blood vessel and the internal layer of outer center, promptly similar having a bath with depurator 7 loam cakes 4 of shower head structure.
Saidly advance blood vessel and steam vent 6 is set near the position of nucleated cell depurator.
Saidly advance blood vessel and syringe needle 8 interfaces are set insert in the blood reclaiming bag 5 and be connected with the blood reclaiming bag.
Saidly advance blood vessel screw socket interface 10 is set, said screw socket 9 interfaces are connected with the blood reclaiming bag through inserting in blood reclaiming bag with its screw socket progressive joint that is complementary.
Said with advance the blood reclaiming bag that blood vessel is connected and be provided with containing mark, every 12-200cm 2Filter membrane disposable filtering blood volume 200-1200ml.
Adopt blood recovery system that autoblood in the art is reclaimed; Wherein cleaning mixture adopts the MAP alserver's solution; Anti-freezing liquid is prepared with the ratio of 1000ml:300mg by MAP alserver's solution and heparin sodium, and the blood after blood recovery system is handled is stored in the blood bag after this utility model nucleated cell filter filters.Evidence can be removed all nucleated cell in the blood, comprises tumor cell.Compared with prior art, protect erythrocyte number and function to greatest extent, guaranteed the quality of the blood that reclaims.
Although through some preferred embodiment with reference to this utility model; This utility model is described; But those of ordinary skill in the art is to be understood that; Can make various changes to it in form with on the details, and the spirit and the scope of this utility model that does not depart from appended claims and limited.

Claims (7)

1. nucleated cell depurator, said depurator comprise the loam cake that is communicated with to advance blood vessel, be communicated with the lower cover of blood vessel and be fixed on loam cake and lower cover between filter membrane, combine closely through welding between said loam cake and lower cover; Said filter membrane is the acetate non-woven fabrics of aperture 7-20 μ m; Saidly enter the center that blood vessel is positioned at loam cake, go out the center that blood vessel is positioned at lower cover, said nucleated cell depurator is a flat; It is characterized in that said depurator lower end is provided with blood transfusion and uses Murphy tube.
2. according to the described nucleated cell depurator of claim 1, it is characterized in that, several crisscross blood guide channels all are set on the said depurator upper and lower cover inwall.
3. according to the described nucleated cell depurator of claim 1; It is characterized in that; Said depurator loam cake is by inside and outside two-layer the composition, and internal layer is offered homodisperse aperture, and the cavity of inside and outside two interlayers communicates with the dispersion apertures of advancing on blood vessel and the internal layer of outer center.
4. according to the described nucleated cell depurator of claim 1, it is characterized in that, saidly advance blood vessel and steam vent is set near the position of nucleated cell depurator.
5. according to the described nucleated cell depurator of claim 1, it is characterized in that, saidly advance blood vessel and needle hub is set inserts in the blood reclaiming bag and be connected with the blood reclaiming bag.
6. according to the described nucleated cell depurator of claim 1, it is characterized in that saidly advance blood vessel the screw socket interface is set, said screw socket interface is connected with the blood reclaiming bag through inserting in blood reclaiming bag with its screw socket progressive joint that is complementary.
7. according to the described nucleated cell depurator of claim 1, it is characterized in that, said with advance the blood reclaiming bag that blood vessel is connected and be provided with containing mark, every 12-200cm 2Filter membrane disposable filtering blood volume 400-1200ml.
CN2011204722672U 2011-11-24 2011-11-24 Nucleated cell purifier Expired - Fee Related CN202366236U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011204722672U CN202366236U (en) 2011-11-24 2011-11-24 Nucleated cell purifier

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011204722672U CN202366236U (en) 2011-11-24 2011-11-24 Nucleated cell purifier

Publications (1)

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CN202366236U true CN202366236U (en) 2012-08-08

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109529444A (en) * 2018-12-17 2019-03-29 刘向晖 The filtering technique and filter of haemocyte in a kind of removal blood sample

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109529444A (en) * 2018-12-17 2019-03-29 刘向晖 The filtering technique and filter of haemocyte in a kind of removal blood sample

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120808

Termination date: 20201124

CF01 Termination of patent right due to non-payment of annual fee