CN209203620U - It is a kind of can bidirectional modulation double optical fiber embedding devices - Google Patents
It is a kind of can bidirectional modulation double optical fiber embedding devices Download PDFInfo
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- CN209203620U CN209203620U CN201821583009.XU CN201821583009U CN209203620U CN 209203620 U CN209203620 U CN 209203620U CN 201821583009 U CN201821583009 U CN 201821583009U CN 209203620 U CN209203620 U CN 209203620U
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- sliding rail
- optical fiber
- connecting rod
- range finder
- screw rod
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Abstract
The utility model discloses it is a kind of can bidirectional modulation double optical fiber embedding devices, including connecting rod, two-way range regulating and controlling mechanism and optic fibre fixing device, the lower end of connecting rod is arranged in two-way range regulator control system, and optic fibre fixing device is arranged on two-way range regulating and controlling mechanism；Two-way range regulating and controlling mechanism includes sliding rail, screw rod and two range finder modules, range finder module is slidably connected with sliding rail, the side that two range finder modules are away from each other is connected through a screw thread with the driven end of screw rod, the both ends of sliding rail are provided with fixed ring, and the aperture that screw rod passes through in fixed ring is arranged in parallel with sliding rail；Adjustable range can control accurate；And distance can be adjusted according to actual needs, and screw rod transmission range accuracy is high, and the amount of feeding is small and is easy to accurately control；Range finder module slides on the slide rail, it is ensured that range finder module and optic fibre fixing device steadily translate；Surgical procedure difficulty, while embedding bilateral optical fiber are reduced, operating time is shortened, alleviates the manipulation strength of patient.
Description
Technical field
The utility model belongs to the experimental provision field of research nervous system, and in particular to it is a kind of can bidirectional modulation double light
Fine embedding device.
Background technique
Light genetic technique is a technical way in current Neuroscience Research field.The technology is by U.S. Stamford
Howard Hughes Institute for Medical Research, university Karl Deisseroth teaches study group's utility model, including two technology modules: light
Quick channel protein expression module and optical fibre channel module.Photosensitive channel protein expresses module: using recombinant adeno-associated virus or slowly
Virus is used as carrier, and photosensitive channel protein gene is transfected into the genome of neuron.It is a series of by film on transcription and translation
Process, photosensitive protein rivet is on neuronal cell film.Optical fibre channel module: photosensitive protein is in the light stimulus by specific wavelength
After can open.Currently used is 473nm blue light.Since the light penetration capacity is poor, light need to be conducted by optical fiber specific
Brain area.Under 473nm blue light illumination, photosensitive channel protein is open, to cause the change of cellular activity.Photosensitive channel protein tool
There is the control accuracy of Millisecond, after light stopping, channel is momentarily turned off.
The big technology modules of the two of the technology are only fitted close and can effectively work.It is improved by many years related using gland
Virus and the technology of slow-virus transfection photosensitive channel protein gene have developed into ripe.But the embedding optical fiber in different experiments room
Mode is inconsistent, serious restriction of the success rate by patient's skilled operation degree.Since brain is stringent symmetrical organ.
When regulating and controlling the activity of specific brain area, generally requires bilateral while regulating and controlling, this just needs experimenter in experimental animals such as mouse
The specific brain area of brain bilateral be accurately inserted into optical fiber.However, although by years of training experimenter, it is also difficult to by optical fiber
It carries out precisely embedding.Precision is lower, and causing the data of multiple identical experiment, there are certain deviations.In order to reduce the interference,
Experimenter has to test using more animal, and great waste is caused in time manpower and material resources.
Utility model content
The purpose of this utility model is to provide a kind of two-way width can quantify the accurate double optical fiber embedding devices adjusted, with
Solve left and right in optical fiber embedded process, inconsistent, the low situation of precision of height.
To reach realization above-mentioned purpose, the utility model adopts the following technical solution: it is a kind of can bidirectional modulation double optical fiber
Embedding device, including connecting rod, two-way range regulating and controlling mechanism and optic fibre fixing device, the setting of two-way range regulator control system are connecting
The lower end of bar, optic fibre fixing device are arranged on two-way range regulating and controlling mechanism；Two-way range regulating and controlling mechanism include sliding rail, screw rod and
Two range finder modules, range finder module are slidably connected with sliding rail, the side that two range finder modules are away from each other with the driven end of screw rod
It is connected through a screw thread, the both ends of sliding rail are provided with fixed ring, and the aperture that screw rod passes through in fixed ring is arranged in parallel with sliding rail.
Range finder module uses electronic range measurement module, is provided with digital screen display on range finder module.
Sliding rail and the tie point of connecting rod are located at the midpoint of sliding rail.
Graduation mark is set on sliding rail, and graduation mark is symmetrical arranged centered on the midpoint of sliding rail.
Graduation mark precision on sliding rail is 0.01mm.
The drive end of screw rod is provided with knob, and the surface of knob is provided with non-slip texture.
The screw pitch or lead of screw rod are 100 μm.
Connecting rod is divided into two sections, and wherein the length of connecting rod lower section is less than the length of connecting rod upper section, connecting rod
Lower section diameter is less than the diameter of connecting rod upper section.
The lower end of connecting rod is provided with a horizontal curved trisection, and horizontal curved trisection is fixedly connected with sliding rail.
The junction of fixed ring and screw rod is provided with locking nut.
Compared with prior art, the utility model at least has the advantages that using two-way quantitative regulating device, adjusts
Pitch is from can control accurate；And distance can be adjusted according to actual needs, using screw rod transmission, be driven range accuracy
Height, the amount of feeding is small and is easy to accurately control；Range finder module slides on the slide rail, it is ensured that range finder module and optic fibre fixing device are steady
Surely it translates；Surgical procedure difficulty, while embedding bilateral optical fiber are reduced, operating time is shortened, alleviates the manipulation strength of patient.
Further, electronic range measurement is accurate to 0.01mm, reduces artificial reading bring deviation；
Further, the midpoint of sliding rail is connect with connecting rod, and graduation mark is arranged on sliding rail, and graduation mark is in sliding rail
Be symmetrical arranged centered on point, when mobile range finder module, can ensure that two range finder module both sides is equidistant, synchronize carry out it is flat
When shifting, single driving source can also be used, while driving two range finder modules mobile.
Further, the graduation mark precision on sliding rail be 0.01mm, make operator be easy observation optical fiber first moved further away from
From and position.
Further, the drive end of screw rod is provided with knob, and the surface of knob is provided with non-slip texture, convenient for operation, rotation
Button increases rotation torque, and operation is lighter to be easy to be precisely controlled.
Further, the screw pitch or lead of screw rod are 100 μm, so that the unit amount of feeding of range unit is smaller, mobile essence
Really.
Further, connecting rod is divided into two sections, and wherein the length of connecting rod lower section is less than the length of connecting rod upper section,
The lower section diameter of connecting rod is less than the diameter of connecting rod upper section, and the lower end of connecting rod is provided with a horizontal curved trisection, horizontal buckling
Section, which is fixedly connected with upper section with sliding rail, to be ensured to occupy little space with other device stable connections, lower end, is reduced to the operator visual field
It influences.
Detailed description of the invention
Fig. 1 is the positive structure diagram of the utility model.
Fig. 2 is the overlooking structure diagram of the utility model.
Fig. 3 is the right side structural representation of the utility model.
Wherein: 1- connecting rod, 2- range finder module, 3- screw rod, 4- fixed ring, 5- knob, 6- sliding rail, 7- fixed screw, 8-
Optical fiber clamping device.
Specific embodiment
Specific embodiment of the utility model is given below, it should be noted that the utility model is not limited to following tool
Body embodiment, all equivalent transformations made on the basis of the technical solutions of the present application each fall within the protection scope of the utility model.
As shown in FIG. 1 to 3, it is a kind of can bidirectional modulation double optical fiber embedding devices, including connecting rod 1, two-way range tune
Mechanism and optic fibre fixing device are controlled, the lower end of connecting rod 1 is arranged in two-way range regulator control system, and optic fibre fixing device is arranged double
To on regulating and controlling mechanism；Two-way range regulating and controlling mechanism includes sliding rail 6, screw rod 3 and two range finder modules 2, range finder module 2 and sliding
Rail 6 is slidably connected, and driven end of the side that two range finder modules 2 are away from each other with screw rod 3 is connected through a screw thread, and the two of sliding rail 6
End is provided with fixed ring 4, and the aperture that screw rod 3 passes through in fixed ring 4 is arranged in parallel with sliding rail 6；Range finder module 2 uses electronic range measurement
Module 2 is provided with digital screen display on range finder module 2；Sliding rail 6 and the tie point of connecting rod 1 are located at the midpoint of sliding rail 6.
Graduation mark is set on sliding rail 6, and graduation mark is symmetrical arranged centered on the midpoint of sliding rail 6；Graduation mark essence on sliding rail 6
Degree is 0.01mm；The drive end of screw rod 3 is provided with knob 5, and the surface of knob 5 is provided with non-slip texture.
The screw pitch or lead of screw rod 3 are 100 μm；Connecting rod 1 is divided for two sections, and wherein the length of 1 lower section of connecting rod is small
In the length of 1 upper section of connecting rod, the lower section diameter of connecting rod 1 is less than the diameter of connecting rod upper section, and the lower end of connecting rod 1 is provided with
One horizontal curved trisection, horizontal curved trisection are fixedly connected with sliding rail 6.
The utility model is preferred, and the junction of fixed ring 4 and screw rod 3 is provided with locking nut.
The overall length 17cm of connecting rod 1, upper section are long 15cm, and the cylindrical metal rod of diameter 0.8cm, lower section is long 2cm, directly
The cylindrical metal rod of diameter 0.4cm；Two-way range regulator control system is connected in connecting rod lower end.Two-way range regulator control system includes:
Indicate the sliding rail, range finder module 2, digital screen display, screw rod, fixed ring, knob of millimeter scale.There is screw thread in fixed ring, to screw rod
Play fixed function；The two cooperates the control accurate, it can be achieved that distance simultaneously.Numerical value can provide a reasonable range
Optic fibre fixing device is connected with electronic range measurement module 2, and optic fibre fixing device includes optical fiber clamping device 8 and fixed spiral shell
Silk 7；Optical fiber clamping device 8 is long 1cm, outer diameter 0.4cm, internal diameter 0.25cm, the circular hollow metal bar of interior depth 0.5cm；Optical fiber
Clamping device side wall is passed through away from the threaded hole for having diameter 0.15cm at the 0.25cm of bottom for fixed screw 7.
Two-way range regulator control system is connected in 1 lower end of connecting rod；Two-way range regulator control system includes: to indicate a millimeter scale
Sliding rail 6, range finder module 2, digital screen display, screw rod, fixed ring 4 and knob.Range finder module 2 is integrated integrated with digital screen display
Device is connected with sliding rail.When 2 inside of range finder module is in the middle line of sliding rail 6, distance is 0mm；When range finder module 2 along sliding rail by
When middle line is mobile to two sides, number is gradually increased；Screw rod 3 is placed through the fixed ring 4 at 6 both ends of sliding rail, the drive end of screw rod 3 with
Knob 5 is connected, and by rotating knob 5, range finder module 2 can be made to translate on the slide rail.
Along being connected in optic fibre fixing device and the range finder module 2 of two-way range regulator control system, including optical fiber clamping device with
Fixed screw, fixed screw are screwed in from the preformed hole of optical fiber clamping device side wall, play fixed function to optical fiber.
As an alternative embodiment of the utility model, screw rod 3 passes through fixed ring 4, and screw rod 3 is arranged in parallel with sliding rail 6,
Feed screw nut is provided on screw rod 3, feed screw nut is fixedly connected with range finder module 2.
The preferred connecting rod 1 of the utility model is welded and fixed with sliding rail 6.
The course of work following steps of the utility model:
1 is inserted into optical fiber on bilateral optic fibre fixing device, tightens fixed screw；
2 rotation knobs 5, adjust the spacing of two range finder modules 2, pass through digital screen display observed reading；
3 exposure skulls, optical fiber is adjusted to above specific brain area, and brill opens skull, and optical fibre slow is inserted into；
4 utilize bone cement by optical fiber and skull close adhesion, after cement solidification, unscrew fixed screw, are raised above shifting
Open the device, the embedding completion of optical fiber.
Claims (10)
1. one kind can bidirectional modulation double optical fiber embedding devices, which is characterized in that including connecting rod (1), two-way range regulate and control machine
Structure and optic fibre fixing device, the setting of two-way range regulator control system are arranged in the lower end of connecting rod (1), optic fibre fixing device two-way
On regulating and controlling mechanism；Two-way range regulating and controlling mechanism includes sliding rail (6), screw rod (3) and two range finder modules (2), range finder module
(2) it is slidably connected with sliding rail (6), the side that two range finder modules (2) are away from each other is connected with the driven end of screw rod (3) by screw thread
It connects, the both ends of sliding rail (6) are provided with fixed ring (4), and aperture of the screw rod (3) on fixed ring (4) is parallel with sliding rail (6) to be set
It sets.
2. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that range finder module (2) is adopted
With electronics range finder module (2), range finder module is provided with digital screen display on (2).
3. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that sliding rail (6) with connect
The tie point of bar (1) is located at the midpoint of sliding rail (6).
4. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that sliding rail is arranged on (6)
Graduation mark, graduation mark are symmetrical arranged centered on the midpoint of sliding rail (6).
5. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that the quarter on sliding rail (6)
Degree line precision is 0.01mm.
6. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that the active of screw rod (3)
End is provided with knob (5), and the surface of knob (5) is provided with non-slip texture.
7. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that the screw pitch of screw rod (3)
Or lead is 100 μm.
8. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that connecting rod (1) is divided into
Two sections, wherein the length of connecting rod (1) lower section is less than the length of connecting rod (1) upper section, and the lower section diameter of connecting rod (1) is small
In the diameter of connecting rod upper section.
9. it is according to claim 1 can bidirectional modulation double optical fiber embedding devices, which is characterized in that under connecting rod (1)
End is provided with a horizontal curved trisection, and horizontal curved trisection is fixedly connected with sliding rail (6).
10. according to claim 1~9 it is described in any item can bidirectional modulation double optical fiber embedding devices, which is characterized in that it is fixed
The junction of ring (4) and screw rod (3) is provided with locking nut.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821583009.XU CN209203620U (en) | 2018-09-27 | 2018-09-27 | It is a kind of can bidirectional modulation double optical fiber embedding devices |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821583009.XU CN209203620U (en) | 2018-09-27 | 2018-09-27 | It is a kind of can bidirectional modulation double optical fiber embedding devices |
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| Publication Number | Publication Date |
|---|---|
| CN209203620U true CN209203620U (en) | 2019-08-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201821583009.XU Active CN209203620U (en) | 2018-09-27 | 2018-09-27 | It is a kind of can bidirectional modulation double optical fiber embedding devices |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110946660A (en) * | 2019-12-30 | 2020-04-03 | 中国科学技术大学 | Adjustable double-hole core inserting needle clamping device and stereotaxic apparatus comprising same |
| CN116081460A (en) * | 2023-04-07 | 2023-05-09 | 阿尔法起重机有限公司 | Low-clearance portal crane |
-
2018
- 2018-09-27 CN CN201821583009.XU patent/CN209203620U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110946660A (en) * | 2019-12-30 | 2020-04-03 | 中国科学技术大学 | Adjustable double-hole core inserting needle clamping device and stereotaxic apparatus comprising same |
| CN110946660B (en) * | 2019-12-30 | 2021-05-07 | 中国科学技术大学 | Adjustable double-hole core inserting needle clamping device and stereotaxic apparatus comprising same |
| CN116081460A (en) * | 2023-04-07 | 2023-05-09 | 阿尔法起重机有限公司 | Low-clearance portal crane |
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