CN208959374U - A kind of general mixed type solid-phase extraction column - Google Patents
A kind of general mixed type solid-phase extraction column Download PDFInfo
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- CN208959374U CN208959374U CN201821237869.8U CN201821237869U CN208959374U CN 208959374 U CN208959374 U CN 208959374U CN 201821237869 U CN201821237869 U CN 201821237869U CN 208959374 U CN208959374 U CN 208959374U
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Abstract
The utility model provides a kind of general mixed type solid-phase extraction column, including column tube, casing, the first push rod and the second push rod, column tube both ends are hatch frame, one end of casing is equipped with the second sieve plate, outlet tube is communicated on the nozzle side wall of column tube one end, one end of casing equipped with the second sieve plate is detachably connected with the column tube mouth close to outlet tube one end, and the first push rod protrudes into the column tube far from outlet tube one end and opposite column tube is reciprocating；Outlet tube and column tube are mutually separated by the first sieve plate, rotating piston has been protruded into activity in outlet tube, the outer diameter of rotating piston and the internal diameter of outlet tube match, side wall close to the outlet tube at the first sieve plate end is equipped with protruding block, one end side wall of the rotating piston protruded into inside outlet tube is equipped with the groove to match with protruding block, and the bottom of outlet tube is equipped with liquid outlet.The extraction column greatly improves extraction efficiency and the working efficiency of operator, therefore it is with a wide range of applications in the preceding processing operation of raw material catalogue.
Description
Technical field
The utility model relates to field of detection of food safety, and in particular to a kind of general mixed type solid-phase extraction column.
Background technique
Currently, solid-phase extraction column (SPE column) is a kind of sample for extracting, separating, be concentrated developed from chromatographic column
Product pretreating device.SPE technology can approximatively regard a kind of simple chromatographic process as, be based on liquid-solid phase chromatographic theory, utilize
The liquid chromatography separation principle of selective absorption and selective elution, by the way of selective absorption, selective elution pair
Sample is enriched with, is separated, is purified, and is a kind of including liquid phase and solid phase physics extraction process.More common method is to make liquid
Sample solution retains wherein measured matter by adsorbent, then appropriate strength solvents is selected to wash away impurity, then with a small amount of solvent
Elution measured matter rapidly, to achieve the purpose that quick separating purification and concentration.Also alternative adsorptive hindrance impurity, and allow
Measured object outflow；Or adsorbing contaminant and measured matter simultaneously, reuse suitable solvent selectivity elution measured matter.Solid phase extraction
It takes the application of column to substantially increase people's lives, very big help is played for the development of scientific research and agricultural aspect.So
And most of extraction columns on existing market are all made of the filler of compacting as adsorbent, however this mode has following lack
Fall into: 1, the porosity between filler reduces, and the contact area of sample and filler declines, and affects the adsorption efficiency of target；2, liquid
The flowing velocity of body sample and eluent in filler reduces, and greatly extends the operating time；3, it is needed when using two class fillers
New extraction column is re-replaced, the practical value of extraction column is reduced；4, the solid-phase extraction column of two class fillers is in depth of packing
In the case where raising, extraction efficiency is further below a kind of single extraction efficiency of the extraction column of filler.
Utility model content
In order to solve the above technical problem of the existing technology, the utility model provides a kind of general mixed type solid phase
Extraction column.
To achieve the goals above, the utility model the following technical schemes are provided:
A kind of general mixed type solid-phase extraction column, including column tube, casing, the first push rod and the second push rod, the column tube two
End is hatch frame, and one end of described sleeve pipe is equipped with the second sieve plate, is communicated with out on the nozzle side wall of described column tube one end
Liquid pipe, one end of the described sleeve pipe equipped with the second sieve plate is detachably connected with the column tube mouth close to outlet tube one end, described
First push rod protrudes into the column tube far from outlet tube one end and opposite column tube is reciprocating；The outlet tube and column tube pass through the
One sieve plate is mutually separated, and rotating piston, the internal diameter phase of the outer diameter and outlet tube of the rotating piston have been protruded into activity in the outlet tube
Match, the side wall close to the outlet tube at the first sieve plate end is equipped with protruding block, protrudes into the rotating piston inside outlet tube
One end side wall is equipped with the groove to match with protruding block, and the bottom of the outlet tube is equipped with liquid outlet；
When casing is docked with column tube, second push rod protrudes into casing and facing sleeve is reciprocating, and two classes are filled out
Material is separately positioned in described sleeve pipe and column tube；
When casing is not docked with column tube, second push rod is protruded into column tube and opposite column tube is reciprocating, filler
It is arranged in the column tube.
Further, clamping groove and clamping block, the clamping block are respectively equipped on the column tube and the flank of casing docking
It is interference fitted with clamping groove, is equipped with sealing ring with the sleeve interface that the column tube is connected to each other.
Further, the clamping block and clamping groove are two pairs, are evenly distributed on the flank of nozzle.
Further, the outer end face of the rotating piston is equipped with knob.
Further, the flank that the column tube and casing are connected to each other is the plane perpendicular with tube body.
The utility model has the advantages that the utility model provides a kind of general mixed type solid-phase extraction column, it is described in the utility model solid
Phase extraction column has the advantage that
1, solid-phase extraction column realizes the mixing of liquid and filler by the way of filler mixing in column, and this hybrid mode makes
The time of contact for obtaining liquid and filler greatly shortens, while greatly improving the contact area of liquid and filler, so that former
When expecting that the adsorption efficiency and eluent of sample and filler are improved the elution efficiency of object, and then shortening Solid Phase Extraction
Between, save the dosage of eluent；
2, the addition of random fill eliminates preceding processing operation of the compacting filler before use；
3, the solid-phase extraction column is accompanied with a casing, and casing, which can choose, to be docked to form two class raw materials of filling with column tube
Solid-phase extraction column, to meet different samples and different extraction purpose extraction demands, casing is with column tube the case where not docking
Under, a kind of filler can also be loaded in a column tube completes extracting operation；
4, the liquid outlet of the extraction column is arranged on one end side wall for the column tube mouth being connected to each other with casing, when casing and column tube
When not docking, by pushing the push rod of outlet tube opposite side that liquid can be discharged；When casing is docked with column tube, outlet tube is located at
Between two tube bodies, pushes the push rod at both ends to centre, liquid can be discharged；
The utility model simple structure and reasonable design, while the structure of cylinder can be adjusted according to different extraction demands,
For the extraction column to the short processing time of sample, volume is few, to greatly improve extraction efficiency and the work of operator
Efficiency, therefore the solid-phase extraction column of the utility model is with a wide range of applications in the preceding processing operation of raw material catalogue.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
In figure: 1, the first push rod；2, the second push rod；3, column tube；4, casing；5, the second sieve plate；6, clamping groove；7, the first sieve
Plate；8, protruding block；9, rotating piston；10, outlet tube；11, liquid outlet；12, clamping block.
Specific embodiment
Further describe the utility model combined with specific embodiments below, but examples are merely exemplary, it is not right
The scope of the utility model constitutes any restrictions.It will be understood by those skilled in the art that without departing from the utility model
Under spirit and scope can details to technical solutions of the utility model and form modify or replace, but these modifications and replace
It changes and each falls in the protection scope of the utility model.
Embodiment 1
A kind of general mixed type solid-phase extraction column, as shown in Figure 1, being pushed away including column tube 3, casing 4, the first push rod 1 and second
Bar 2,3 both ends of column tube are hatch frame, and one end of described sleeve pipe 4 is equipped with the second sieve plate 5, close to described 3 one end of column tube
Outlet tube 10 is communicated on nozzle side wall, one end of the described sleeve pipe 4 equipped with the second sieve plate 5 and the column close to 10 one end of outlet tube
Nozzle is detachably connected, and the interior and opposite column tube 3 of column tube 3 that first push rod 1 protrudes into separate 10 one end of outlet tube is made past
Multiple movement；The outlet tube 10 and column tube 3 are mutually separated by the first sieve plate 7, and rotating piston has been protruded into activity in the outlet tube 10
9, the internal diameter of the outer diameter and outlet tube 10 of the rotating piston 9 matches, close to the side wall of the outlet tube 10 at the first sieve plate end
It is equipped with protruding block 8, one end side wall of the rotating piston 9 protruded into outlet tube 10 inside with protruding block 8 equipped with matching
The bottom of groove, the outlet tube 10 is equipped with liquid outlet 11；
When casing 4 is docked with column tube 3, second push rod 2 protrudes into casing 4 and facing sleeve 4 is reciprocating, and two
Class filler is separately positioned in described sleeve pipe 4 and column tube 3；
When casing 4 is not docked with column tube 3, second push rod 2 is protruded into column tube 3 and opposite column tube is reciprocating,
Filler is arranged in the column tube 3.
Clamping groove 6 and clamping block 12,12 He of clamping block are respectively equipped on the flank that the column tube 3 and casing 4 dock
Clamping groove 6 is interference fitted, and 4 contact surface of casing being connected to each other with the column tube 3 is equipped with sealing ring.
The clamping block 12 and clamping groove 6 are two pairs, are evenly distributed on the flank of nozzle.
The outer end face of the rotating piston 9 is equipped with knob.
The flank that the column tube 3 and casing 4 are connected to each other is the plane perpendicular with tube body.
Solid-phase extraction column described in the utility model has following two operation format:
(1) casing is not docked with column tube
When casing is not docked with column tube, the second push rod 2 and the first push rod 1 are separately positioned on the both ends of column tube 3, column tube 3
Inside it is put into a kind of filler or mixed type filler；Rotating piston 9 screws in outlet tube 1 and makes the recessed of protruding block 8 and 9 end of rotating piston
Slot matches, to block outlet tube trickle, pours into raw material catalogue to be adsorbed from the corresponding column tube mouth of the first push rod 1,
The second push rod 2 and the first push rod 1 are pushed up and down, so that raw material catalogue and filler are come into full contact with and adsorbed completely；It is mixed
After conjunction, rotating piston 9 is stretched out into a part, so that the end of rotating piston 9 is detached from protruding block 8, rotation rotating piston 9 to rotate
The groove face liquid outlet 11 of plug 9, compresses the second push rod 2 and the first push rod 1 makes raw material liq sample after processing from out
It is flowed out in liquid mouth；
After raw material liq sample flows out, rotating piston 9 is blocked by outlet tube 10 with identical operation, is then pushed away from first
The corresponding column tube mouth of bar 1 pours into eluent, the second push rod 2 and the first push rod 1 is pushed, so that eluent is filled with filler
Tap is touched and elutes object from filler, and eluent is discharged and is collected using ibid identical operation.
(2) casing is docked with column tube
The clamping block 12 of 4 flank of casing is aligned to the clamping groove 6 of 3 flank of column tube, so that column tube 3 is mutually clamped with casing 4, is led to
The fastness that ensure that clamping using the snap fit of interference fit is crossed, while the sealing ring being arranged on casing 4 ensure that connection
Column tube 3 and casing 4 are separated by the leakproofness at place, the second sieve plate 5 that casing 4 is equipped with, so that in two pipes respectively
Two class raw materials are added, to meet the separation demand of different target object.Wherein, the absorption of raw material catalogue and elution action are the same as in (1)
The mode of operation that the casing is not docked with column tube.
Claims (5)
1. a kind of general mixed type solid-phase extraction column, which is characterized in that including column tube, casing, the first push rod and the second push rod, institute
Stating column tube both ends is hatch frame, and one end of described sleeve pipe is equipped with the second sieve plate, on the nozzle side wall of described column tube one end
It is communicated with outlet tube, the column tube mouth of one end of the described sleeve pipe equipped with the second sieve plate and close outlet tube one end is detachably in succession
It connects, first push rod protrudes into the column tube far from outlet tube one end and opposite column tube is reciprocating；The outlet tube and column
Pipe is mutually separated by the first sieve plate, and rotating piston has been protruded into activity in the outlet tube, the outer diameter of the rotating piston and outlet tube
Internal diameter matches, and the side wall close to the outlet tube at the first sieve plate end is equipped with protruding block, protrudes into described inside outlet tube
One end side wall of rotating piston is equipped with the groove to match with protruding block, and the bottom of the outlet tube is equipped with liquid outlet；
When casing is docked with column tube, second push rod protrudes into casing and facing sleeve is reciprocating, two class fillers point
It She Zhi not be in described sleeve pipe and column tube；
When casing is not docked with column tube, second push rod is protruded into column tube and opposite column tube is reciprocating, filler setting
In the column tube.
2. a kind of general mixed type solid-phase extraction column according to claim 1, which is characterized in that the column tube and casing pair
It is respectively equipped with clamping groove and clamping block, the clamping block and clamping groove interference fit on the flank connect, is connected to each other with the column tube
Sleeve interface be equipped with sealing ring.
3. a kind of general mixed type solid-phase extraction column according to claim 2, which is characterized in that the clamping block and clamping
Slot is two pairs, is evenly distributed on the flank of nozzle.
4. a kind of general mixed type solid-phase extraction column according to claim 1, which is characterized in that the outer end of the rotating piston
Face is equipped with knob.
5. a kind of general mixed type solid-phase extraction column according to claim 1, which is characterized in that the column tube and casing phase
The flank of docking is the plane perpendicular with tube body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821237869.8U CN208959374U (en) | 2018-08-02 | 2018-08-02 | A kind of general mixed type solid-phase extraction column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821237869.8U CN208959374U (en) | 2018-08-02 | 2018-08-02 | A kind of general mixed type solid-phase extraction column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208959374U true CN208959374U (en) | 2019-06-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201821237869.8U Active CN208959374U (en) | 2018-08-02 | 2018-08-02 | A kind of general mixed type solid-phase extraction column |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393947A (en) * | 2019-09-04 | 2019-11-01 | 广东省生物工程研究所（广州甘蔗糖业研究所） | A kind of preparation method of chromatography column apparatus and chromatographic column |
| CN111097193A (en) * | 2019-12-31 | 2020-05-05 | 绿城农科检测技术有限公司 | Quick solid phase extraction device |
-
2018
- 2018-08-02 CN CN201821237869.8U patent/CN208959374U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110393947A (en) * | 2019-09-04 | 2019-11-01 | 广东省生物工程研究所（广州甘蔗糖业研究所） | A kind of preparation method of chromatography column apparatus and chromatographic column |
| CN110393947B (en) * | 2019-09-04 | 2024-03-26 | 广东省生物工程研究所（广州甘蔗糖业研究所） | Chromatographic column device and preparation method of chromatographic column |
| CN111097193A (en) * | 2019-12-31 | 2020-05-05 | 绿城农科检测技术有限公司 | Quick solid phase extraction device |
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