CN208912101U - A kind of cell-preservation liquid bottle of double film layer functions - Google Patents
A kind of cell-preservation liquid bottle of double film layer functions Download PDFInfo
- Publication number
- CN208912101U CN208912101U CN201820476772.6U CN201820476772U CN208912101U CN 208912101 U CN208912101 U CN 208912101U CN 201820476772 U CN201820476772 U CN 201820476772U CN 208912101 U CN208912101 U CN 208912101U
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- Prior art keywords
- cell
- liquid
- bottle
- layers
- prefiltration
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- 239000007788 liquid Substances 0.000 title claims abstract description 31
- 238000004321 preservation Methods 0.000 title claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 18
- 238000011045 prefiltration Methods 0.000 claims abstract description 12
- 210000000270 basal cell Anatomy 0.000 claims abstract description 10
- 239000012528 membrane Substances 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 abstract description 13
- 239000012535 impurity Substances 0.000 abstract description 6
- 210000003743 erythrocyte Anatomy 0.000 abstract description 5
- 210000004969 inflammatory cell Anatomy 0.000 abstract description 5
- 238000003860 storage Methods 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 7
- 210000002919 epithelial cell Anatomy 0.000 description 4
- 210000003097 mucus Anatomy 0.000 description 4
- 238000012216 screening Methods 0.000 description 4
- 208000019065 cervical carcinoma Diseases 0.000 description 3
- 238000009595 pap smear Methods 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Centrifugal Separators (AREA)
- Sampling And Sample Adjustment (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
This patent is related to a kind of plastic bottle containing double medium filtration nethike embrane for holding cell-preservation liquid for liquid-based cell sample manufacturing.More particularly to a kind of guarantor's storage bottle for realizing the impurity in double medium filtration and removal sample, inflammatory cell, red blood cell, Mini Tissue cell.It is made of plastic bottle body, prefiltration net, two layers of filtering net film, bottle cap and suction pipe, can be realized liquid basal cell and fast and safely effectively filter and screen.
Description
Technical field
The present invention relates to it is a kind of for liquid-based cell sample manufacturing hold cell-preservation liquid containing double medium filtration nethike embrane
Plastic bottle.It is widely used in exfoliative cytology, more particularly to a kind of impurity realized in double medium filtration and removal sample, filter
Except guarantor's storage bottle of inflammatory cell, red blood cell, Mini Tissue cell.Can be realized liquid basal cell fast and safely effectively filtering and
Screening, can more effectively be enriched with the epithelial cell of diagnostic significance, improve the slice-making quality of liquid basal cell sample.
Background technique
Cervical carcinoma is multiple one of the malignant tumour of women, cervical carcinoma be can early find, early treatment, can cure one
Kind disease.TCT is mainly used for the screening of cervical carcinoma, and the process of domestic liquid-based cell sample manufacturing is all realized by hand, and what is used is heavy
Drop plate, feed bin safety is poor, needs to overturn when removing liquid in feed bin and topple over, easy cross contamination, and safety is poor.
The screening of cast-off cells includes following operation: being sampled using sample-taking brush, protects in storage bottle and saved, vibrated
And it is uniformly dissolved, Thinprep pap test film-making and dye piece, microscopically observation.Flaking method based on manual film-making, including from
Heart sedimentation, membrane type film-making etc., centrifugal settling method are a kind of current medical most commonly used cast-off cells film-makers of testing agency
Method.
The exfoliated cell preservative fluid bottle of centrifugal settling method film-making at present is the plastic bottle of not filter screen mostly, after sampling
Sample-taking brush, which is directly placed into, to be saved in liquid plastic bottle, and liquid basal cell, which is eluted in, to be saved in liquid, and impurity and mucus etc. are with cast-off cells
It is attached on glass slide, influences slice-making quality and sees the observation and analytical judgment of piece doctor.
Prefiltration nethike embrane of the present invention can effectively impurity screening and mucus, it is only necessary to which normally oscillation dissolution can be realized, side
Just it operates；Synchronous two layers of filtering net film can filter out inflammatory cell, red blood cell, Mini Tissue cell, can more effectively be enriched with
There is the epithelial cell of diagnostic significance, improve the slice-making quality of liquid basal cell sample, it is ensured that film-making and dye tablet quality.
Summary of the invention
As shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4, Fig. 5, Fig. 6, a kind of cell-preservation liquid bottle of double film layer functions, feature exists
In, including plastic bottle body, prefiltration net, two layers of filtering net film, bottle cap and suction pipe, wherein prefiltration mesh number 120-150 mesh, two
1000 mesh of layer filtering net film mesh number, it is after the filtering of prefiltration nethike embrane and two layers of filtering net film filter out that suction pipe position, which corresponds to liquid,
Effective liquid basal cell.
Detailed description of the invention
Fig. 1 is three-dimensional figure after plastic bottle body of the present invention is transparent
Fig. 2 is three-dimensional figure after plastic bottle body of the present invention is transparent
Fig. 3 is three dimensional sectional view of the present invention
Fig. 4 is front view of the present invention
Fig. 5 is the cross-sectional view of left view of the present invention
Fig. 6 is the cross-sectional view that the present invention looks up direction
1. plastic bottle body；2. two layers of filtering net film；3. prefiltration net；4. bottle cap；5. suction pipe.
Liquid in bottle is divided into three regions: containing impurity and mucus, the promising useful liquid in middle layer in the prefiltration nethike embrane of upper layer
Basal cell contains inflammatory cell, red blood cell, Mini Tissue cell below two layers of filtering net film.
Specific embodiment
A kind of cell-preservation liquid bottle of double film layer functions by plastic bottle body, prefiltration net, two layers of filtering net film, bottle cap and
Suction pipe is constituted, and the invention major function part is the prefiltration screen membrane mesh number 120- of the cell-preservation liquid bottle of double film layer functions
150 mesh filter out impurity and mucus；Two layers of 1000 mesh of filtering net film mesh number, have filtered out inflammatory cell, red blood cell, Mini Tissue
Cell；Liquid basal cell effectively filter and screen, the epithelial cell of diagnostic significance can be more effectively enriched with, mention
The high slice-making quality of liquid basal cell sample, while ensure that the accuracy of inspection.
Doctor is sampled using sample-taking brush, sample-taking brush with sample be put into protect storage bottle in saved, save liquid into
Row pretreatment, acquisition have the specimen preserving liquid bottle of cell sample to be transmitted to laboratory, and laboratory operation personnel receive guarantor's storage bottle
When, vibrated and be uniformly dissolved, it is no longer necessary to add separating liquid and cleaning solution, do not need to be shaken and be centrifuged again with it is quiet
It sets, can directly take middle layer to there is the epithelial cell of diagnostic significance to carry out Thinprep pap test film-making and dye piece, system is greatly saved
It the piece time, improves work efficiency, while better ensuring that the quality control process of sample.
Claims (2)
1. a kind of cell-preservation liquid bottle of double film layer functions, which is characterized in that including plastic bottle body, prefiltration net, two layers of mistake
Screen membrane, bottle cap and suction pipe, wherein prefiltration mesh number 120-150 mesh, two layers of 1000 mesh of filtering net film mesh number.
2. a kind of cell-preservation liquid bottle of double film layer functions according to claim 1, it is characterised in that suction pipe position pair
Answering liquid is effective liquid basal cell after the filtering of prefiltration nethike embrane and two layers of filtering net film filter out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820476772.6U CN208912101U (en) | 2018-04-04 | 2018-04-04 | A kind of cell-preservation liquid bottle of double film layer functions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820476772.6U CN208912101U (en) | 2018-04-04 | 2018-04-04 | A kind of cell-preservation liquid bottle of double film layer functions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208912101U true CN208912101U (en) | 2019-05-31 |
Family
ID=66691699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820476772.6U Expired - Fee Related CN208912101U (en) | 2018-04-04 | 2018-04-04 | A kind of cell-preservation liquid bottle of double film layer functions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208912101U (en) |
-
2018
- 2018-04-04 CN CN201820476772.6U patent/CN208912101U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: Cell preserving fluid bottle with double-membrane layering function Effective date of registration: 20200611 Granted publication date: 20190531 Pledgee: Bank of China Limited Nanjing City Branch Pledgor: NANJING FROEASY TECHNOLOGY DEVELOPMENT Co.,Ltd. Registration number: Y2020980002988 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20210727 Granted publication date: 20190531 Pledgee: Bank of China Limited Nanjing City Branch Pledgor: NANJING FROEASY TECHNOLOGY DEVELOPMENT Co.,Ltd. Registration number: Y2020980002988 |
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| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A cell preservation solution bottle with double membrane layering function Effective date of registration: 20210728 Granted publication date: 20190531 Pledgee: Bank of China Limited by Share Ltd. Nanjing Xuanwu sub branch Pledgor: NANJING FROEASY TECHNOLOGY DEVELOPMENT Co.,Ltd. Registration number: Y2021980006952 |
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| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220602 Granted publication date: 20190531 Pledgee: Bank of China Limited by Share Ltd. Nanjing Xuanwu sub branch Pledgor: NANJING FROEASY TECHNOLOGY DEVELOPMENT CO.,LTD. Registration number: Y2021980006952 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A cell preservation solution bottle with double membrane layering function Effective date of registration: 20220607 Granted publication date: 20190531 Pledgee: Bank of China Limited by Share Ltd. Nanjing Xuanwu sub branch Pledgor: NANJING FROEASY TECHNOLOGY DEVELOPMENT CO.,LTD. Registration number: Y2022980007274 |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190531 |
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| CF01 | Termination of patent right due to non-payment of annual fee |