CN112871473B - Quick film-making subassembly suitable for horizontal centrifuge - Google Patents
Quick film-making subassembly suitable for horizontal centrifuge Download PDFInfo
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- CN112871473B CN112871473B CN202110036792.8A CN202110036792A CN112871473B CN 112871473 B CN112871473 B CN 112871473B CN 202110036792 A CN202110036792 A CN 202110036792A CN 112871473 B CN112871473 B CN 112871473B
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- container
- slide
- fixing groove
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- horizontal centrifuge
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Centrifugal Separators (AREA)
Abstract
The invention discloses a quick slide making assembly suitable for a horizontal centrifuge, which comprises a container, a slide, filter paper, a support piece and a fixing cap, wherein the container is provided with a slide groove; the container is of a tubular cylindrical structure, the top of the container is provided with an inlet for placing a tissue sample, and the bottom of the container is provided with an outlet for flowing out and filtering the tissue sample; the container is detachably placed in or taken out of the supporting piece, the lower end of the supporting piece is also provided with a first fixing groove for placing a slide, and the outlet of the container is aligned with the first fixing groove; the fixing cap is used for pressing the container into the support; after the container is placed in the support piece, the fixing cap presses the container into the support piece, the outlet of the container is pressed against the slide, and the filter paper is positioned outside the outlet. The slide making device can be better suitable for a horizontal centrifugal liquid-based thin-layer cell machine, only a container, a slide and a fastener are assembled and put into a horizontal centrifugal machine, the manufacturing difficulty is reduced, the efficiency is improved, the sample slide can be quickly made by using the slide making clamp, and the cost expenditure of an inspection department is saved to the maximum extent.
Description
Technical Field
The invention relates to liquid-based thin-layer cell detection, in particular to a rapid slide making assembly suitable for a horizontal centrifuge.
Background
The liquid-based thin-layer cell detection method comprises the following steps: using a sampling brush, using a preserving fluid to rinse the sampling brush and preserving the sample, shaking and dissolving, preparing a liquid-based thin-layer cell, and observing by a microscope. In the prior art, smear preparation is usually carried out manually, when a specimen is prepared manually, exfoliated cells on a glass slide are difficult to coat uniformly, and in addition, due to the fact that the specimen for sampling the exfoliated cells contains mucus, red blood cells and other impurities, the background of a specimen smear is not clean and clear, so that the observation analysis and diagnosis of a pathologist are influenced.
The invention discloses a slide making clamp for a centrifugal liquid-based thin-layer cell slide making machine, which is published in 12/07/2018 by CN108956218A, and the slide making clamp for the centrifugal liquid-based thin-layer cell slide making machine is characterized by comprising a box body for clamping a glass slide, a liquid storage hopper for storing sample liquid and a flow guide pipe, wherein the box body comprises a front side plate, a rear side plate and a bottom plate for connecting the front side plate and the rear side plate, a coating hole is formed in the position, corresponding to the glass slide, on the front side plate, one end of the flow guide pipe is communicated with the coating hole, the other end of the flow guide pipe is communicated with the liquid storage hopper, and a flow guide part inclining downwards from the coating hole to the liquid storage hopper is arranged in the flow guide pipe. The invention solves the problems that in the use process of the existing slide clamp, too much cell thin layer sample liquid is accumulated at the opening during centrifugation because the slide glass is propped against the opening, and finally the sample liquid is diffused along the slide glass, so that the background of the slide glass is fuzzy and not clean, and the analysis and the diagnosis are influenced.
The above scheme has the following disadvantages: the film making clamp in the patent can only be applied to the cell centrifugal smear machine matched with the film making clamp, but the horizontal centrifugal machine which is widely used at present can not be applied. During operation, the horizontal centrifuge causes a liquid-based flow by rotating at high speed. Therefore, designing a sheet making clip suitable for a horizontal centrifuge without changing the structure of the horizontal centrifuge is one of the technical problems to be solved urgently at present.
Disclosure of Invention
The invention aims to provide a quick tabletting assembly suitable for a horizontal centrifuge, and solves the problem that the prior art cannot be perfectly adapted to a horizontal centrifugal liquid-based thin-layer cell machine.
In order to realize the purpose of the invention, the invention adopts the following technical scheme: a quick slide making assembly suitable for a horizontal centrifuge comprises a slide making device and a slide glass, wherein the slide making device comprises a container, the slide glass, filter paper, a supporting piece and a fixing cap; the container is in a tubular cylindrical structure, the top of the container is provided with an inlet for placing a tissue sample, and the bottom of the container is provided with an outlet for flowing out and filtering the tissue sample; the container is detachably placed in or taken out of the supporting piece, the lower end of the supporting piece is also provided with a first fixing groove for placing a slide, and the outlet of the container is aligned to the first fixing groove; the fixing cap is used for pressing the container into the support; after the container is placed into the supporting piece, the fixing cap presses the container into the supporting piece, the outlet of the container is pressed against the slide, and the filter paper is positioned outside the outlet; the middle part of the glass slide is provided with a second fixing groove, the glass slide is detachably connected with the first fixing groove of the supporting piece, and the glass slide can be placed into and fixed in the second fixing groove after being taken out of the first fixing groove.
Compared with the prior art, the quick tabletting assembly applicable to the horizontal centrifuge, which adopts the technical scheme, has the following beneficial effects:
the quick slide making assembly suitable for the horizontal centrifugal machine can be better suitable for the horizontal centrifugal liquid-based thin-layer cell machine, and only a container, a slide and a fastener are assembled and placed in the horizontal centrifugal machine, so that the manufacturing difficulty is reduced, and the efficiency is improved.
The slide making clamp can be applied to the existing horizontal centrifuge, namely, on the premise that the centrifuge equipment is not replaced, the sample slide can be quickly made by using the slide making clamp, and the cost expenditure of a laboratory is saved to the maximum extent.
The rapid slide preparation assembly is divided into a slide and a slide preparation device, the slide preparation device can rapidly prepare slides, and the prepared slides can be placed on the corresponding slides for observation and inspection.
Preferably, the second fixing groove is further provided with a side hole, and the side hole is used for facilitating an operator to clamp the slide by using tweezers.
Preferably, the slide glass is further provided with a pressing sheet, and the pressing sheet is used for pressing the slide glass in the second fixing groove.
Preferably, the slide glass is provided with two pressing sheets in total, and the pressing sheets are symmetrical about the center of the second fixing groove.
Preferably, be equipped with the spacing groove on the support piece, the container is equipped with spacing portion, and when spacing portion put into the spacing groove, the relative support piece of container is unable rotatory again, and the container is no longer rotatory after putting into support piece, can effectively ensure that the container can not rock and form too big gap between slide and filter paper, avoids sample liquid to excessively spill, if the gap is too big, sample liquid spills too much, then causes the testing result to have some deviations easily.
Preferably, the support piece outer end is equipped with the external screw thread, and the locking cap is equipped with the internal thread, but locking cap screw in external screw thread compresses tightly spacing portion in spacing groove bottom portion, makes the container relatively fixed on support piece, and the container opening supports on the slide, through rotatory locking cap for the locking cap pushes down the container, and the container carries filter paper and supports firmly on the slide, so as to avoid the container to rock and the liquid that brings spills.
Preferably, the lower end of the container is further provided with a limiting convex ring for fixing the filter paper, the filter paper is wrapped on the periphery of the limiting convex ring, the filter paper is fixed through the limiting convex ring, and the filter paper is firmly fixed by being pressed by the container.
Preferably, the support member is provided with side openings for observing the removal of the container and the slide, the side openings firstly reducing the material consumption of the support member and allowing the operator to observe the state inside the container (the amount, color and other visually observable information of the liquid inside the container).
Drawings
FIG. 1 is a schematic diagram of an embodiment of a rapid tableting assembly suitable for use in a horizontal centrifuge according to the invention.
Fig. 2 is a schematic diagram of a fast tableting assembly suitable for use in a horizontal centrifuge in an embodiment.
Fig. 3 is a schematic diagram of a fast tableting assembly suitable for use in a horizontal centrifuge in an embodiment.
FIG. 4 is a schematic view showing the structure of a slide glass in the example.
Reference numerals: 1. a container; 10. a limit convex ring; 11. a limiting part; 2. glass slide; 3. a support member; 30. a first fixing groove; 31. a limiting groove; 4. a fixing cap; 5. filtering paper; 6. a glass slide; 60. a second fixing groove; 61. side holes.
Detailed Description
The invention is further described below with reference to the accompanying drawings.
A rapid slide making assembly suitable for a horizontal centrifuge as shown in fig. 1 to 4 includes a maker including a container 1, a slide 2, a filter paper 5, a supporter 3 and a fixing cap 4, and a slide 6.
The container 1 is of a tubular cylindrical structure, the top of the container 1 is provided with an inlet for placing a tissue sample, and the bottom of the container 1 is provided with an outlet for flowing and filtering the tissue sample;
the container 1 is detachably placed in or taken out of the support member 3, the lower end of the support member 3 is also provided with a first fixing groove 30 for placing the slide 2, and the outlet of the container 1 is aligned with the first fixing groove 30;
the fixing cap 4 is used to press the container 1 into the support 3;
after the container 1 is placed in the support 3, the fixing cap 4 presses the container 1 into the support 3, the outlet of the container 1 is pressed against the slide 2, and the filter paper 5 is positioned outside the outlet.
The supporting member 3 is provided with a limiting groove 31, the container 1 is provided with a limiting part 11, and when the limiting part 11 is placed in the limiting groove 31, the container 1 can not rotate relative to the supporting member 3.
The outer end of the support piece 3 is provided with an external thread, the fixing cap 4 is provided with an internal thread, the fixing cap 4 can be screwed in the external thread to compress the limiting part 11 at the bottom of the limiting groove 31, so that the container 1 is relatively fixed on the support piece 3, and the opening of the container 1 is propped against the glass slide 2.
The lower end of the container 1 is also provided with a limiting convex ring 10 used for fixing the filter paper 5, and the filter paper 5 is wrapped on the periphery of the limiting convex ring 10.
The support 3 is provided with a side opening for taking out the observation container 1 and the slide 2.
The middle part of the slide 6 is provided with a second fixing groove 60, the slide 2 is detachably connected with the first fixing groove 30 of the support 3, and the slide 2 can be placed and fixed in the second fixing groove 60 after being taken out of the first fixing groove 30. The second fixing groove 60 is also provided with a side hole 61 for facilitating an operator to grip the slide 2 using tweezers.
The specific implementation mode of the invention is as follows:
1. the slide 2 is placed in the first fixing groove 30, the filter paper 5 is sleeved on one side of the limiting convex ring 10, and the container 1 is pressed against the slide 2 to clamp the filter paper 5 firmly.
2. The container 1 is inserted into the bottom of the support 3.
3. At this time, the fixing cap 4 is screwed with the support 3 so that the container 1 is firmly fixed in the support 3 and put into a horizontal centrifugal liquid-based thin layer cell machine.
4. The horizontal centrifugal liquid-based thin layer cell machine is started, the container 1 moves the internal tissue slurry towards the open side of the container 1 with centrifugation, the liquid is filtered through the filter paper 5, and the specimen is left in the middle of the slide 2.
5. After centrifugation, all the specimens to be observed remain on the slide 2, the fixing cap 4 is removed, the container 1 is removed and the slide 2 is removed again.
6. The taken slide 2 is prevented from being in the second fixing groove 60 of the slide 6, the rotary pressing piece 62 presses the slide 2 in the second fixing groove 60, and at the moment, the slide 6 is taken into a detection instrument to observe the slide 2.
The foregoing is a preferred embodiment of the present invention, and it will be apparent to those skilled in the art that various changes and modifications may be made without departing from the spirit of the invention, and these should be considered to be within the scope of the invention.
Claims (8)
1. The utility model provides a quick film-making subassembly suitable for horizontal centrifuge which characterized in that: comprises a slide maker and a slide glass (6),
the slide maker comprises a container (1), a slide (2), filter paper (5), a support (3) and a fixing cap (4);
the container (1) is of a tubular cylindrical structure, the top of the container (1) is provided with an inlet for placing a tissue sample, and the bottom of the container (1) is provided with an outlet for flowing out and filtering the tissue sample;
the container (1) is detachably placed in or taken out of the supporting piece (3), a first fixing groove (30) for placing the slide (2) is further formed in the lower end of the supporting piece (3), and an outlet of the container (1) is aligned to the first fixing groove (30);
the fixing cap (4) is used for pressing the container (1) into the support (3);
after the container (1) is placed in the support piece (3), the fixing cap (4) presses the container (1) into the support piece (3), the outlet of the container (1) is pressed against the slide (2), and the filter paper (5) is positioned outside the outlet;
the middle part of the glass slide (6) is provided with a second fixing groove (60), the glass slide (2) is detachably connected with the first fixing groove (30) of the supporting piece (3), and the glass slide (2) can be placed into and fixed in the second fixing groove (60) after being taken out of the first fixing groove (30).
2. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 1, wherein: the second fixing groove (60) is also provided with a side hole (61) for facilitating an operator to clamp the slide (2) by using tweezers.
3. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 1, wherein: the slide glass (6) is also provided with a pressing sheet (62), and the pressing sheet (62) is used for pressing the slide glass (2) in the second fixing groove (60).
4. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 3, wherein: the glass slide (6) is provided with two pressing sheets (62), and the pressing sheets (62) are centrosymmetric with respect to the second fixing groove (60).
5. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 1, wherein: the supporting piece (3) is provided with a limiting groove (31), the container (1) is provided with a limiting part (11), and when the limiting part (11) is placed in the limiting groove (31), the container (1) can not rotate relative to the supporting piece (3).
6. A rapid tableting assembly adapted for use in a horizontal centrifuge as claimed in claim 5, wherein: the outer end of the support piece (3) is provided with an external thread, the fixing cap (4) is provided with an internal thread, the fixing cap (4) can be screwed in the external thread to compress the limiting part (11) at the bottom of the limiting groove (31), so that the container (1) is relatively fixed on the support piece (3), and the opening of the container (1) is abutted to the glass slide (2).
7. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 1 wherein: the lower end of the container (1) is further provided with a limiting convex ring (10) for fixing the filter paper (5), and the filter paper (5) wraps the periphery of the limiting convex ring (10).
8. A rapid tableting assembly suitable for use in a horizontal centrifuge as claimed in claim 1, wherein: the supporting piece (3) is provided with a side opening for taking out the observation container (1) and the slide (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110036792.8A CN112871473B (en) | 2021-01-12 | 2021-01-12 | Quick film-making subassembly suitable for horizontal centrifuge |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110036792.8A CN112871473B (en) | 2021-01-12 | 2021-01-12 | Quick film-making subassembly suitable for horizontal centrifuge |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112871473A CN112871473A (en) | 2021-06-01 |
| CN112871473B true CN112871473B (en) | 2022-06-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110036792.8A Active CN112871473B (en) | 2021-01-12 | 2021-01-12 | Quick film-making subassembly suitable for horizontal centrifuge |
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| CN (1) | CN112871473B (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952239A (en) * | 1997-06-12 | 1999-09-14 | Shandon, Inc. | Cytology chamber with port to receive collection bottle and method of use |
| CN101246096A (en) * | 2008-03-12 | 2008-08-20 | 郑明� | Centrifugal pellet mill and hanging cradle used for the same |
| CN202216865U (en) * | 2011-07-01 | 2012-05-09 | 长沙康柏恩医疗科技有限公司 | Filter and settling device for fast smear making of liquid based cytology |
| CN203606191U (en) * | 2013-11-26 | 2014-05-21 | 上海宇度医学科技股份有限公司 | Thin-layer liquid-based cell slide maker |
| CN106092679A (en) * | 2016-06-05 | 2016-11-09 | 镇江立昌智能装备有限公司 | Liquid basal cell natural subsidence pelletizer |
| CN205719705U (en) * | 2016-06-25 | 2016-11-23 | 南京健邦锦源医疗仪器有限公司 | A kind of Thinprep pap test film-making folder |
| CN107807028A (en) * | 2017-11-22 | 2018-03-16 | 张祝妹 | Thinprep pap test film-making device |
| CN108956219A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Thinprep pap test pelleter is pressed from both sides with film-making |
-
2021
- 2021-01-12 CN CN202110036792.8A patent/CN112871473B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952239A (en) * | 1997-06-12 | 1999-09-14 | Shandon, Inc. | Cytology chamber with port to receive collection bottle and method of use |
| CN101246096A (en) * | 2008-03-12 | 2008-08-20 | 郑明� | Centrifugal pellet mill and hanging cradle used for the same |
| CN202216865U (en) * | 2011-07-01 | 2012-05-09 | 长沙康柏恩医疗科技有限公司 | Filter and settling device for fast smear making of liquid based cytology |
| CN203606191U (en) * | 2013-11-26 | 2014-05-21 | 上海宇度医学科技股份有限公司 | Thin-layer liquid-based cell slide maker |
| CN106092679A (en) * | 2016-06-05 | 2016-11-09 | 镇江立昌智能装备有限公司 | Liquid basal cell natural subsidence pelletizer |
| CN205719705U (en) * | 2016-06-25 | 2016-11-23 | 南京健邦锦源医疗仪器有限公司 | A kind of Thinprep pap test film-making folder |
| CN108956219A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Thinprep pap test pelleter is pressed from both sides with film-making |
| CN107807028A (en) * | 2017-11-22 | 2018-03-16 | 张祝妹 | Thinprep pap test film-making device |
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| CN112871473A (en) | 2021-06-01 |
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