CN105067397A - Liquid-based thin cell slide preparation device - Google Patents
Liquid-based thin cell slide preparation device Download PDFInfo
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- CN105067397A CN105067397A CN201510422833.1A CN201510422833A CN105067397A CN 105067397 A CN105067397 A CN 105067397A CN 201510422833 A CN201510422833 A CN 201510422833A CN 105067397 A CN105067397 A CN 105067397A
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- liquid
- slide
- firm banking
- cell
- strainer tube
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Abstract
The invention relates to a liquid-based thin cell slide preparation device. The device comprises a rotary centrifugal mechanism and a plurality of liquid-loading slide preparation mechanisms arranged on the peripheral sides of the rotary centrifugal mechanism separately, wherein each liquid-loading slide preparation mechanism comprises a fixing base and filter pipes vertically inserted at the upper part of the fixing base, and rubber gaskets are arranged at the lower parts of the filter pipes. The invention aims to provide the liquid-based thin cell slide preparation device which is convenient to mount and dismount and good in slice preparation effect. The liquid-based thin cell slide preparation device has the advantages as follows: the liquid loading mechanisms are hinged with the rotary centrifugal mechanisms, so that cell sap in the filter pipes is perpendicularly thrown to slides, and the cell sap is uniformly spread; 2, a filter net is arranged at the lower part of each filter pipe and used for filtering the cell sap in the corresponding filtering pipe, so that cell sap entering the corresponding slide doesn't contain impurities; 3, compared with an L-shaped pipe, each straight tubular filtering pipe can contain more cell sap, and cells on each slide are more sufficient.
Description
Technical field
The present invention relates to a kind of Thinprep pap test pelletizer.
Background technology
ThinPrep cytologic test adopts liquid-based thin-layer cell detection system detect cervical cell and carry out cytology specification diagnosis.
ThinPrep cytologic test principle of work is by gathering vagina or cervical secretions, immerse in liquid basal cell reagent treatment after obtaining cast-off cells and process, cracking composition in reagent can carry out cracking to red blood cell, removes the interference that red blood cell causes assay; Frozen composition simultaneously in reagent can preserve the fixing valuable cell such as leucocyte, Exfoliative cells; And the effective cell be wrapped in mucus is fully separated, prevent the loss of valuable cell.Effective cell is prepared into cell suspension, removes mucus to the interference of film-making finally by filter centrifugation method, make cast-off cells thin slice.The methods such as available HE dyeing, pap staining or other immunohistochemical stainings make cell color, analyzed the cellular morphology checking vagina or uterine neck again by manual observation, diagnose the change in early stage of cervix cancer and cancer thereof, Human infectious warts virus and herpes simplex infections.
Existing centrifugal pelleter complex structure, dismounting inconvenience; And the cell concentration that film-making obtains is few, tiling effects is poor, background is unclean, detects bring difficulty to post analysis.
Summary of the invention
The object of the present invention is to provide a kind of easy accessibility, the Thinprep pap test pelletizer that production effect is good.
Object of the present invention is achieved through the following technical solutions: a kind of Thinprep pap test pelletizer, and it comprises rotating centrifugal mechanism and point some Zhuan Ye producer agencies be located on rotary centrifuge structure outer circumferential side; Described Zhuan Ye producer agency and rotating centrifugal mechanism are hinged, and jointed shaft is perpendicular to the line between Zhuan Ye producer agency center of gravity and rotating centrifugal mechanism turning axle; Described Zhuan Ye producer agency comprises firm banking and is vertically plugged on the strainer tube on firm banking top, the bottom of described firm banking is provided with the slide insertion groove extended in the horizontal direction, and the top of firm banking is provided with the body insert port matched with strainer tube lower end, described body insert port is connected with slide insertion groove, and described strainer tube bottom is provided with cushion rubber.
Compared to prior art, the invention has the advantages that:
1. Zhuan Ye producer agency and rotating centrifugal mechanism are hinged, and when rotating centrifugal mechanism rotates, rotating the centrifugal force produced can throw away Zhuan Ye producer agency, makes vertical the getting rid of on slide of the cell liquid in strainer tube, ensure that the even tiling of cell liquid;
2. the bottom of strainer tube is provided with screen pack, can filter the cell liquid in strainer tube, makes the cell liquid entered on slide not have impurity, and the slide clean background of gained, does not affect detection;
3. straight-cylindrical strainer tube is compared to L shape pipe, and the cell liquid that can put into is more, makes the cell concentration on slide more sufficient.
Accompanying drawing explanation
Fig. 1 is the vertical view of a kind of Thinprep pap test pelletizer of the present invention embodiment.
Fig. 2 is the side view of Thinprep pap test pelletizer.
Fig. 3 is the vertical view of firm banking.
Fig. 4 is the side view of firm banking.
Fig. 5 is the perspective view of firm banking.
Fig. 6 is the structural representation of strainer tube.
Label declaration: 1 rotating disk, 1-1 base fixed gap, 1-2 lug boss, 2 firm bankings, 2-1 slide insertion groove, 2-2 body insert port, 2-3 fix ear, 2-4 locating slot, the spacing draw-in groove of 2-5,2-6 guided way, 3 strainer tubes, 3-1 limiting card, 4 cushion rubbers, 5 screen packs.
Embodiment
Below in conjunction with Figure of description and embodiment, content of the present invention is described in detail:
Be the embodiment schematic diagram of a kind of Thinprep pap test pelletizer provided by the invention as shown in Figures 1 to 6.
A kind of Thinprep pap test pelletizer, it comprises rotating centrifugal mechanism and point some Zhuan Ye producer agencies be located on rotary centrifuge structure outer circumferential side; Described Zhuan Ye producer agency and rotating centrifugal mechanism are hinged, and jointed shaft is perpendicular to the line between Zhuan Ye producer agency center of gravity and rotating centrifugal mechanism turning axle.
Described Zhuan Ye producer agency comprises firm banking 2 and is vertically plugged on the strainer tube 3 on firm banking 2 top, the bottom of described firm banking 2 is provided with the slide insertion groove 2-1 extended in the horizontal direction, and the top of firm banking 2 is provided with the body insert port 2-2 matched with strainer tube 3 lower end, described body insert port 2-2 is connected with slide insertion groove 2-1, and described strainer tube 3 bottom is provided with cushion rubber 4.
When rotating centrifugal mechanism is static, strainer tube 3 is arranged in vertical, and namely parallel with the rotating shaft of rotating disk 1, the slide insertion groove 2-1 on firm banking 2 extends along the radial position of rotating disk 1; When rotating centrifugal mechanism rotates, because Zhuan Ye producer agency is hinged on the outer circumferential side of rotating centrifugal mechanism, it rotates the centrifugal force produced and Zhuan Ye producer agency can be thrown away, finally make strainer tube 3 in horizontal level, vertical for cell liquid in strainer tube 3 gets rid of on slide by centrifugal force, ensure that the even tiling of cell liquid; After rotating centrifugal mechanism closes, slide and the cell liquid on it slowly can recover horizontal level under the centrifugal force reduced gradually, and the cell liquid that slide tiles can not slippage again.
Described rotating centrifugal mechanism comprises rotating disk 1, and the outer circumferential side of described rotating disk 1 is provided with some base fixed gap 1-1, is provided with two corresponding lug boss 1-2 in described base fixed gap 1-1; Described firm banking 2 both sides are provided with the two perpendicular fixing ear 2-3 put, and the lateral surface of described fixing ear 2-3 is provided with the locating slot 2-4 cooperatively interacted with lug boss 1-2, and described locating slot 2-4's is opening down.The dismounting between rotating centrifugal mechanism and Zhuan Ye producer agency is convenient in above-mentioned design.During use, first the locating slot 2-4 lower ending opening on fixing ear 2-3 is aimed at the lug boss 1-2 in base fixed gap 1-1, then firm banking 2 is placed straight down, lug boss 1-2 is made to be resisted against the upper end of locating slot 2-4, form a hinged point of fixity, when rotating centrifugal mechanism rotates, firm banking 2 can flip to the outside, equilibrium centrifugation power.
The lower openings of described locating slot 2-4 is hydraucone.Bell-mouth structure of air plays guide effect, is convenient to locating slot 2-4 rapid alignment lug boss 1-2.
Described slide insertion groove 2-1 upper side is provided with the guided way 2-6 for being pressed against slide upper side.
Slide insertion groove 2-1 front end is provided with the recess be convenient to slide and inserted and take out.
Described cushion rubber 4 is set in strainer tube 3 lower tube.Strainer tube 3 carries out sealing by cushion rubber 4 and slide to be fixed, and prevents the cell liquid on slide from leaking.
Screen pack 5 is provided with in described strainer tube 3.Cell liquid in screen pack 5 pairs of strainer tubes 3 filters, and makes the cell liquid entered on slide not have impurity, and the slide clean background of gained, does not affect detection.
Straight-cylindrical strainer tube 3 is compared to L shape pipe, and its pipe body part vertical with slide is more, therefore can put into more cell liquid, and then makes the cell concentration on slide more sufficient.
The lower outside wall of described strainer tube 3 is provided with two limiting card 3-4, described firm banking 2 top and be positioned at body insert port 2-2 periphery and be provided with two and hold limiting card 3-4 along clockwise direction or counterclockwise precession and the spacing draw-in groove 2-5 of clamping location.
Two spacing draw-in groove 2-5 and two are fixing, and ear 2-3 divides the surrounding being located at body insert port 2-2, fixes the surrounding of strainer tube 3, and fixing ear 2-3 madial wall is provided with the depressed part coordinated with strainer tube 3 outline.
The cross section of described spacing draw-in groove 2-5 is the arc raised up.Above-mentioned be arranged so that limiting card 3-4 in precession spacing draw-in groove 2-5 be an elder generation tight after the tight again process of pine, the second half section of arc is a downtrend on the one hand, make strainer tube 3 in precession, have a downforce, make cushion rubber 4 be connected with slide more firm; Another aspect can effectively prevent strainer tube 3 from deviating from spacing draw-in groove 2-5.
Claims (7)
1. a Thinprep pap test pelletizer, is characterized in that: it comprises rotating centrifugal mechanism and point some Zhuan Ye producer agencies be located on rotary centrifuge structure outer circumferential side; Described Zhuan Ye producer agency and rotating centrifugal mechanism are hinged, and jointed shaft is perpendicular to the line between Zhuan Ye producer agency center of gravity and rotating centrifugal mechanism turning axle; Described Zhuan Ye producer agency comprises firm banking (2) and is vertically plugged on the strainer tube (3) on firm banking (2) top, the bottom of described firm banking (2) is provided with the slide insertion groove (2-1) extended in the horizontal direction, and the top of firm banking (2) is provided with the body insert port (2-2) matched with strainer tube (3) lower end, described body insert port (2-2) is connected with slide insertion groove (2-1), and described strainer tube (3) bottom is provided with cushion rubber (4).
2. Thinprep pap test pelletizer according to claim 1, it is characterized in that: described rotating centrifugal mechanism comprises rotating disk (1), the outer circumferential side of described rotating disk (1) is provided with some base fixed gap (1-1), is provided with two corresponding lug bosses (1-2) in described base fixed gap (1-1); Described firm banking (2) both sides are provided with the two perpendicular fixing ears (2-3) put, and the lateral surface of described fixing ear (2-3) is provided with the locating slot (2-4) cooperatively interacted with lug boss (1-2), described locating slot (2-4) opening down.
3. Thinprep pap test pelletizer according to claim 2, is characterized in that: the lower openings of described locating slot (2-4) is hydraucone.
4. Thinprep pap test pelletizer according to claim 1, is characterized in that: described slide insertion groove (2-1) upper side is provided with the guided way (2-6) for being pressed against slide upper side.
5. Thinprep pap test pelletizer according to claim 1, is characterized in that: be provided with screen pack (5) in described strainer tube (3).
6. the Thinprep pap test pelletizer according to claim 1-5 any one, it is characterized in that: the lower outside wall of described strainer tube (3) is provided with two limiting cards (3-1), described firm banking (2) top and be positioned at body insert port (2-2) periphery and be provided with two and hold limiting card (3-1) along clockwise direction or counterclockwise precession and the spacing draw-in groove (2-5) of clamping location.
7. Thinprep pap test pelletizer according to claim 6, is characterized in that: the cross section of described spacing draw-in groove (2-5) is the arc raised up.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510422833.1A CN105067397A (en) | 2015-07-17 | 2015-07-17 | Liquid-based thin cell slide preparation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510422833.1A CN105067397A (en) | 2015-07-17 | 2015-07-17 | Liquid-based thin cell slide preparation device |
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| CN105067397A true CN105067397A (en) | 2015-11-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510422833.1A Pending CN105067397A (en) | 2015-07-17 | 2015-07-17 | Liquid-based thin cell slide preparation device |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018045A (en) * | 2016-07-04 | 2016-10-12 | 邱加伟 | Pipetting mechanism for sectioning and staining cells |
| CN106318856A (en) * | 2016-08-11 | 2017-01-11 | 马杰 | Cell enrichment device |
| CN107389400A (en) * | 2017-07-10 | 2017-11-24 | 柴传程 | One kind is easily assembled medical slice production folder |
| CN108517311A (en) * | 2018-04-20 | 2018-09-11 | 麦克奥迪（厦门）医疗诊断系统有限公司 | For detaching and the separating liquid of enrichment of cell, kit and its application |
| CN112268773A (en) * | 2020-11-11 | 2021-01-26 | 吉林万方医疗科技有限公司 | Liquid-based cell full-automatic sheet making machine |
| CN113702125A (en) * | 2021-08-12 | 2021-11-26 | 姚香怡 | Full-automatic sheet making machine and sheet making process method |
| CN118376803A (en) * | 2024-06-26 | 2024-07-23 | 长沙远安生物科技有限公司 | Sample injection device for liquid-based thin-layer cell pelleter |
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| US20050001124A1 (en) * | 2003-05-23 | 2005-01-06 | Litke Mark R. | Lamp mounting assembly |
| CN101246096A (en) * | 2008-03-12 | 2008-08-20 | 郑明� | Centrifugal pellet mill and hanging cradle used for the same |
| CN201965046U (en) * | 2010-12-28 | 2011-09-07 | 三明市博昇模具塑胶制品有限公司 | Liquid-based cell sample manufacturing plastic clip |
| CN203117021U (en) * | 2013-03-28 | 2013-08-07 | 张向华 | Cell smear device |
| CN204389249U (en) * | 2014-12-31 | 2015-06-10 | 珠海市丽拓发展有限公司 | Storehouse is hung in centrifugal film-making |
| CN204731087U (en) * | 2015-07-17 | 2015-10-28 | 邱加伟 | Thinprep pap test pelletizer |
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2015
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050001124A1 (en) * | 2003-05-23 | 2005-01-06 | Litke Mark R. | Lamp mounting assembly |
| CN101246096A (en) * | 2008-03-12 | 2008-08-20 | 郑明� | Centrifugal pellet mill and hanging cradle used for the same |
| CN201965046U (en) * | 2010-12-28 | 2011-09-07 | 三明市博昇模具塑胶制品有限公司 | Liquid-based cell sample manufacturing plastic clip |
| CN203117021U (en) * | 2013-03-28 | 2013-08-07 | 张向华 | Cell smear device |
| CN204389249U (en) * | 2014-12-31 | 2015-06-10 | 珠海市丽拓发展有限公司 | Storehouse is hung in centrifugal film-making |
| CN204731087U (en) * | 2015-07-17 | 2015-10-28 | 邱加伟 | Thinprep pap test pelletizer |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018045A (en) * | 2016-07-04 | 2016-10-12 | 邱加伟 | Pipetting mechanism for sectioning and staining cells |
| CN106318856A (en) * | 2016-08-11 | 2017-01-11 | 马杰 | Cell enrichment device |
| CN107389400A (en) * | 2017-07-10 | 2017-11-24 | 柴传程 | One kind is easily assembled medical slice production folder |
| CN108517311A (en) * | 2018-04-20 | 2018-09-11 | 麦克奥迪（厦门）医疗诊断系统有限公司 | For detaching and the separating liquid of enrichment of cell, kit and its application |
| CN112268773A (en) * | 2020-11-11 | 2021-01-26 | 吉林万方医疗科技有限公司 | Liquid-based cell full-automatic sheet making machine |
| CN113702125A (en) * | 2021-08-12 | 2021-11-26 | 姚香怡 | Full-automatic sheet making machine and sheet making process method |
| CN113702125B (en) * | 2021-08-12 | 2024-01-26 | 姚香怡 | Full-automatic pelleter and pelleter process method |
| CN118376803A (en) * | 2024-06-26 | 2024-07-23 | 长沙远安生物科技有限公司 | Sample injection device for liquid-based thin-layer cell pelleter |
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Application publication date: 20151118 |
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