CN208838236U - A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat - Google Patents
A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat Download PDFInfo
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- CN208838236U CN208838236U CN201820732771.3U CN201820732771U CN208838236U CN 208838236 U CN208838236 U CN 208838236U CN 201820732771 U CN201820732771 U CN 201820732771U CN 208838236 U CN208838236 U CN 208838236U
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Abstract
The utility model discloses a kind of tracheae epiglottis opening locators suitable for the noninvasive respiratory tract administration of rat, it include the retainer body made of food-grade macromolecule polymer material, retainer body is in up big and down small conical hollow structure, the height of retainer body is 5cm to 5.5cm, the lower end diameter of retainer body is 0.2cm to 0.4cm, and the lower end of the longitudinal cross-section of retainer body is spherical structure;The upper end of retainer body is laterally fixed at least one handle.The advantage is that: structure is simple, and it is easy to use, safe, it can be realized quick, accurate dropleting medicine-feeding;Using up big and down small conical hollow structure as retainer body, facilitate the irradiation of transmitted light source, rat trachea can be made sufficiently to expose, drug drip process is enable to be completed rapidly and accurately;And the setting of retainer body upper end handle, not only facilitate the gripping of locator, also facilitate will locator be inserted into rat oral procedures in be fixed and direction adjust.
Description
Technical field
The utility model relates to laboratory rat medicine-feeding technology fields, and especially a kind of noninvasive respiratory tract of rat that is suitable for is given
The tracheae epiglottis opening locator of medicine.
Background technique
In contemporary life science, zoopery is indispensable.Various physiological phenomenons and pathomechanism need mostly
It to illustrate or confirm by zoopery.Safe and effective medication is to ensure that the key of Success in Experiment, is experiment knot
Fruit is accurate, true and reliable premise.With the development of science and technology, the progress of human civilization, animal welfare is also increasingly by people
Attention, guarantee that experimental animal enjoys due welfare, reduce animal suffering to the greatest extent during the experiment, provided for it easypro
Suitable, painless experimental situation respects its tremendous contribution made for the raw medical scientific undertakings of the mankind, is embodied in zoopery
One of main path of humanistic care.
Tracheal instillation is the main experimental methods of intrarterial or contamination, and most of experimental animal Intratracheal administration is at present
Invasive, and not can avoid esophagus and be strayed into.In addition, experimenter uses tracheotomy toward contact for the accuracy for guaranteeing administration,
Rat neck skin and Muscle disruption are made into tracheae exposure, drug instils via the notch of tracheae exposure, or with sharp sample introduction
Device punctures tracheae to realize the purpose of tracheal instillation administration.Such method has open wound, is easy to damage experimental animal, and
With the extension of time, zoogenetic infection rate increases, it is possible to cause animal dead, it is also possible to the accuracy of experimental result is influenced,
And it is unfavorable for long-time Intratracheal administration repeatedly;In addition, tracheotomy method is complicated, biggish manpower and time are needed, it can not
Suitable for high-volume zoopery.
Summary of the invention
It is simple that for the current state of the art, the technical problem to be solved by the utility model is to provide structures, user
Just, safety, a kind of tracheae epiglottis suitable for the noninvasive respiratory tract administration of rat that can be realized quick, accurate dropleting medicine-feeding are open
Locator.
Technical solution adopted by the utility model to solve the above technical problems is as follows:
A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat, includes by food-grade macromolecule
Retainer body made of polymer material, retainer body are in up big and down small conical hollow structure, the height of retainer body
Degree is 5cm to 5.5cm, and the lower end diameter of retainer body is 0.2cm to 0.4cm, the lower end of the longitudinal cross-section of retainer body
For spherical structure;The upper end of retainer body is laterally fixed at least one handle.
The technical measures of optimization further include:
The upper end diameter of above-mentioned retainer body is 1cm to 1.2cm.
The quantity of above-mentioned handle is two, and two handles are located along the same line.
The length of above-mentioned handle is 2cm to 3cm.
The width of above-mentioned handle is 0.8cm to 1.2cm.
The section of above-mentioned handle is ellipsoidal structure.
A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat of the utility model, structure letter
It is single, it is easy to make, using up big and down small conical hollow structure as retainer body, facilitate the irradiation of transmitted light source, it can
It exposes rat trachea sufficiently, drug drip process is enable to be completed rapidly and accurately;And retainer body upper end handle is set
Set, not only facilitate the gripping of locator, also facilitate will locator be inserted into rat oral procedures in be fixed and direction adjust.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of embodiment one in the utility model;
Fig. 2 is the cutaway view Amplified image of locator longitudinal cross-section lower end in the utility model;
Fig. 3 is the structural schematic diagram of embodiment two in the utility model.
Specific embodiment
The utility model is described in further detail below in conjunction with figure embodiment.
It is as shown in Figure 1 to Figure 3 the structural schematic diagram of the utility model,
Appended drawing reference therein are as follows: height H, length L, retainer body 1, spherical structure 11, handle 2.
Embodiment one,
A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat, includes by food-grade macromolecule
Retainer body 1 made of polymer material, retainer body 1 are in up big and down small conical hollow structure, retainer body 1
Height H is 5cm to 5.5cm, and the lower end diameter of retainer body 1 is 0.2cm to 0.4cm, the longitudinal cross-section of retainer body 1
Lower end be spherical structure 11;The upper end of retainer body 1 is laterally fixed with a handle 2.
Retainer body 1 and handle 2 are made of food-grade high molecular polymer;Such as food-grade PP, food-grade PE etc..
In embodiment, the upper end diameter of retainer body 1 is 1cm to 1.2cm.
In embodiment, the length L of handle 2 is 2cm to 3cm.
In embodiment, the width of handle 2 is 0.8cm to 1.2cm.
In embodiment, the section of handle 2 is ellipsoidal structure.
Using the retainer body 1 of up big and down small conical hollow structure, facilitate the irradiation of transmitted light source, rat can be made
Tracheae sufficiently exposes, and drug drip process is enable to be completed rapidly and accurately;And the setting of handle 2, not only facilitate locator
Hold, also facilitate will locator be inserted into rat oral procedures in be fixed and direction adjust.Cooperate rat physiological characteristic, be
Rat trachea is set sufficiently to expose, the lower end diameter of retainer body 1 is 0.2cm to 0.4cm;In addition cooperate rat
Oral cavity structure, the height of retainer body 1 are 5cm to 5.5cm.The spherical structure 11 of 1 lower end of retainer body, it is fixed to can be avoided
When the device insertion of position, the oral cavity of rat is caused to scratch.
Embodiment two,
Locator in the present embodiment is similar to the locator structure in embodiment one, the difference is that in the present embodiment,
The quantity of handle 2 is two, and two handles 2 are located along the same line.Two handles being located along the same line 2 are set, are inserted into
Behind the oral cavity of rat, handle 2 is stretched out from two sides, and fixation is more stable;In addition, two sides are respectively provided with handle 2, can be avoided in operation
Some blind areas make to operate more convenient.
It is suitable for the noninvasive tracheal instillation administration method of laboratory rat using one kind of this locator, comprising the following steps:
Step 1: after rat anesthesia, by rat vertical hanging on glass plate, rat oral cavity in the experimenter visual field hereinafter,
Use shadowless lamp for transmitted light source;
Step 2: an experimenter, which involves rat tongue after fixing rat head, is exposed to oral external, and will
Light-resource fousing is in rat oral cavity, and another one experimenter is then slowly inserted into locator by oral cavity until tracheae epiglottis, works as observation
When breathing generated white bubble to rat trachea and float up and down, indicate that rat trachea exposure portion is correct,
Step 3: via locator that drug is slow as administration device using microsyringe or blunt nosed sample introduction needle at this time
Pipe is instilled, after drug drip, listens rat lung sound with stethoscope, when hearing rat lung moist rales,
It indicates that drug can smoothly enter into tracheae, removes locator after the completion of drug drip.
Using the locator of the utility model, the noninvasive tracheal instillation administration to rat can be realized, it will not injury rats
Tracheae, operating method is accurately, conveniently, safely;During instillation, tracheae is high-visible, can be avoided drug and is strayed into esophagus, instils
Method is simple, and dosage is accurate, can freely control dosage, and micro- dosage and larger dose are all applicable.
The most preferred embodiment of the utility model has illustrated, the various change or remodeling made by those of ordinary skill in the art
All without departing from the scope of the utility model.
Claims (6)
1. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat, includes by food-grade polyphosphazene polymer
Retainer body (1) made of object material is closed, it is characterized in that: the retainer body (1) is in up big and down small conical hollow
The height (H) of structure, the retainer body (1) is 5cm to 5.5cm, and the lower end diameter of the retainer body (1) is
0.2cm to 0.4cm, the lower end of the longitudinal cross-section of the retainer body (1) are spherical structure (11);The locator
The upper end of main body (1) is laterally fixed at least one handle (2).
2. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat according to claim 1,
Be characterized in: the upper end diameter of the retainer body (1) is 1cm to 1.2cm.
3. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat according to claim 2,
Be characterized in: the quantity of the handle (2) is two, and two handles (2) are located along the same line.
4. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat according to claim 3,
Be characterized in: the length (L) of the handle (2) is 2cm to 3cm.
5. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat according to claim 4,
Be characterized in: the width of the handle (2) is 0.8cm to 1.2cm.
6. a kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat according to claim 5,
Be characterized in: the section of the handle (2) is ellipsoidal structure.
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CN201820732771.3U CN208838236U (en) | 2018-05-17 | 2018-05-17 | A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat |
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CN201820732771.3U CN208838236U (en) | 2018-05-17 | 2018-05-17 | A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat |
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CN208838236U true CN208838236U (en) | 2019-05-10 |
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CN201820732771.3U Active CN208838236U (en) | 2018-05-17 | 2018-05-17 | A kind of tracheae epiglottis opening locator suitable for the noninvasive respiratory tract administration of rat |
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