CN208297231U - A kind of big bottled sample liquids automatic subpackaging is set - Google Patents
A kind of big bottled sample liquids automatic subpackaging is set Download PDFInfo
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- CN208297231U CN208297231U CN201820957411.3U CN201820957411U CN208297231U CN 208297231 U CN208297231 U CN 208297231U CN 201820957411 U CN201820957411 U CN 201820957411U CN 208297231 U CN208297231 U CN 208297231U
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- sample
- syringe needle
- bottle
- module
- incubator
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Abstract
The utility model discloses a kind of big bottled sample liquids automatic subpackagings to set.The utility model includes sample transportation module, sample crawl flip module, syringe needle plug mechanism, peristaltic pump, current-limiting apparatus and incubator operation module.The utility model design is first automatically transported sample to designated position by transportation module, then sample bottle is grabbed by sample turning manipulator, is directed at syringe needle mechanism, inserts the needle into big bottle, after the completion, it opens peristaltic pump and realizes being drawn into incubator automatically for sample；When the sample sets bacterium completion in incubator, different culture mediums is pumped into respectively by current-limiting apparatus into incubator bottle.The utility model is simple in construction, easy to disassemble and assemble, takes up space smaller, it is easy to accomplish automatic operation.
Description
Technical field
The utility model belongs to food and medicine analysis field, is related to (being more than or equal to 250 milliliters extremely to loaded on big bottle test sample
500 milliliters) in sample carry out automatic subpackaging in three collect bacterium bottle mechanism.
Background technique
The key project that sterility test is controlled as food and medicine quality, in newest 2010 editions GMP " pharmaceutical production quality
Management regulation " and 2015 editions pharmacopeia be proposed and clearly require, be enterprise and regulatory agency to the important of the qualified examination and test of products
Project.The laminar flow platform of one-way gas flow is installed in normal sterile inspection in a controlled environment, and a collection is placed on laminar flow platform
Bacterium instrument completes sterility test.
China's Sterility testing still rests on the complete manually-operated stage, and drug contamination caused by artificial maloperation is not in detection
It is detected and accounts for the 80% of Sterility testing result fault rate, in addition, artificial progress Sterility testing operating efficiency is low, high labor cost
High, universal to Sterility testing brings certain difficulty.And it is flooded with hydrogen peroxide gas in Sterility testing environment and various has
Drug toxicity is chronically at the health for being unfavorable for testing staff in the environment of Sterility testing.In addition, carrying out Sterility testing pair
The technical threshold of operator is higher, and 80% is postgraduate's educational background in the operator of China's Sterility testing, before life's work, also needs
By the post training of longer period of time.Since working environment is severe, great work intensity, employment in training process and later
In the stage, brain drain is serious, leads to the status that employment is difficult, recruitment is difficult, is unfavorable for the sustainable development of industry, makes national drug safety
Lack and ensures.
Summary of the invention
In view of the shortcomings of the prior art, the utility model provides a kind of big bottled sample liquids automatic subpackagings to set.
The utility model technical solution adopted for solving the technical problem is:
The utility model includes sample transportation module, sample crawl flip module, syringe needle plug mechanism, peristaltic pump, current limliting
Device and incubator operation module.
The sample transportation module is mainly made of the belt pulley transport mechanism built on pedestal, and big bottle sample is horizontal
In accommodating in bracket, the receiving bracket is placed on belt.
The sample crawl flip module is realized by gantry-type mechanical arm, including motor, catching robot and lead screw, is grabbed
Take manipulator that the rotary motion of motor is converted into the grasp force of manipulator, manipulator is realized under the action of motor and lead screw
It moves up and down.
With syringe needle manipulator is grabbed, the syringe needle manipulator of grabbing has cooperated with catching robot for the syringe needle plug mechanism
It is operated at the plug of syringe needle, syringe needle is fixed on the fixture that can be mutually attracted with the calutron grabbed in syringe needle manipulator
On；The other end of syringe needle is connected to collection bacterium bottle by hose.
The peristaltic pump and current limliting dress for providing liquid transfer power are provided on the hose line of syringe needle to collection bacterium bottle
It sets.
The current-limiting apparatus includes straight-line electric arbor, servo motor and current limliting slot, and the servo motor is used for hose
It is pressed into current limliting slot, the straight-line electric arbor controls the conducting of current limliting slot inner flexible tube by control extrusion head.
The incubator operation module includes slider-crank mechanism, elevating mechanism and liquid outlet groove, collects bacterium bottle and its fixture
Shift vertical position onto from horizontal position under the action of slider-crank mechanism, the bottleneck of collection bacterium bottle upward, and the fluid hole of bottom of bottle
It is placed exactly in the surface of liquid outlet groove, the liquid in collection bacterium bottle bottle can be flowed into liquid outlet groove.
The utility model has the beneficial effects that the utility model realizes that bottled sample is automatically transported to specified greatly in isolator
Position automatically grabs sample bottle, and syringe needle exchanges plug for automatically, automatically turns on peristaltic pump, automatic current limiting, the upper and lower cap stopper of automatic cover simultaneously
The operation such as hose is sheared, syringe needle catching robot structure is simple, the cost of system is utmostly reduced, for three hose difficulties
The difficulty of remaining current-limiting operation is connected in realization any one, the method directly controlled using three linear motors only needs to control
Any one motor moving axis head, which compresses hose, can be thus achieved the current limliting of hose, and structure is simple, succinct, easy to operate maximum limit
Degree reduces costs.Generally speaking, during the utility model largely alleviates Sterility testing, complicated hose
Installation, the installation of current limliting sum aggregate bacterium bottle, the plug of syringe needle exchange for operation and may the false positive bacterium as caused by maloperation operate, energy
Enough functions of effectively improving Sterility testing, realize the full-automatic intelligent of whole process.
Detailed description of the invention
The side general structure schematic diagram of Fig. 1 the utility model；
The other side general structure schematic diagram of Fig. 2 the utility model；
Fig. 3 is for trial jar robot manipulator structure schematic diagram；
Fig. 4 syringe needle plug modular structure schematic diagram；
Fig. 5 incubator operation module schematic diagram；
Fig. 6 current-limiting apparatus schematic diagram.
Specific embodiment
Below by drawings and examples, the technical solution of the utility model is described in further detail.
The utility model, will be in trial jar by the realization of serial automatic operation process mainly for big bottled test sample
Sample be dispensed into connected collection bacterium bottle and add corresponding culture medium.The utility model design includes that following module is real
Existing relevant operation: sample bottle is transported to specified station by exterior sterilization cabin by sample transportation module；Sample grabs flip module,
Specified angle rotation is completed when can be convenient crawl sample bottle, and extracting for subsequent sample；Syringe needle plug module, can be convenient by
Syringe needle is inserted into sample bottle；Wriggling pump module opens the pump after completing syringe needle insertion work, and turning for liquid may be implemented
It moves；Current limliting module based on motor can carry out any conducting operation control to hose in subsequent culture medium filling process
System；Incubator operation module may be implemented incubator rotation, rise, and cooperation cutting mechanism realizes liquid with cap stopper mechanism is pulled out
Filter operation is finally completed the shearing and encapsulation of incubator sample.
As depicted in figs. 1 and 2, whole mechanical structure specifically includes that sample delivery module；Sample crawl flip module,
Wriggling pump module, current-limiting apparatus module and incubator operation module be wherein:
Sample delivery module: since big bottle sample 2 is to be horizontally placed on 1 the inside of bracket for accommodating and fixing it, cradle bottom surface
Area can be bigger, therefore the movement can be completed with belt transmission, therefore conveyor module is mainly by building the skin on pedestal
Belt wheel transport mechanism composition.There are manipulators to grab space at position among bottle, and manipulator is facilitated to grab.
As shown in figure 3, sample crawl flip module includes: for the fixed bracket 3 of trial jar manipulator, sample catching robot pawl
12.Specific structure: sample catching robot pawl 12 is fixed on the fixed bracket 3 of manipulator, the fixed bracket 3 of manipulator can laterally and
Longitudinal movement, gripper have crawl and rotating function, realize big bottling liquid sample grabbing syringe needle position from conveyer belt position
It sets, after insertion needle, rotates 180 degree, peristaltic pump 6 opens the extraction work that can start liquid.
Wriggling pump module: peristaltic pump 6 is made of current mature peristaltic pump system, can when its unlatching for hose mechanism
To realize the extraction work of liquid；When incubator one end syringe needle is inserted into sample bottle, other end incubator is placed in the fixed dress of incubator
It sets, when intermediate three hoses are had already accessed to inside current-limiting apparatus, opens peristaltic pump, it can be by the liquid in sample bottle by pressure
Body is pumped into incubator.
As shown in figure 4, the syringe needle in syringe needle plug module 4 is fixed on one can mutually be attracted with manipulator calutron
Fixture on, sliding rail 7 with longitudinal movement sliding block 13 on, manipulator is fixed on transverse shifting sliding block 14, and syringe needle is together with fixture
After being picked up by manipulator, by plc control system control manipulator servo motor by scheduled route syringe needle is moved to it is specified
Position makes hose be in the state that is straightened, and by syringe needle with hose be moved to wriggling head slot and current limliting groove location just on
Side, this is that a set of one end is syringe needle, and other end is connected the device of three collection bacterium bottles by hose, facilitates and carry out next behaviour
Make.
As shown in figure 5, the slider-crank mechanism 16 in incubator operation module 10 is located at the lower section of medium bottle pedestal, it is whole
A slider-crank mechanism is located on lifter plate, and lifter plate is located at the position of the intermediate through slot of liquid outlet groove plate, can be in stepping
The rotation of motor driven lead screw to realize moving up and down for slider-crank mechanism, complete incubator and emit by cooperation cap stopper pull-plug device 11
The removal and capping work of plug cover after culture medium installs additional and emit plug, then mobile by cutting mechanism 9 and cutting mechanism
The shearing of the realization thribble of sliding block 8,15.
As shown in fig. 6, hose current limliting module includes: current-limiting apparatus baffle 5, incubator hose 17；Hose clamping motor 18；
Current limliting linear motor 19,20,21.Concrete mechanism: current-limiting apparatus is needed mainly for the addition of culture medium when adding culture medium
Culture medium is pumped into corresponding incubator bottle respectively, is at this moment needed in an addition culture medium into three culture bottles
In addition limitation flows into other two culture bottle, hose clamping motor 18 is placed on level board, and there is block facet on clamping motor head
Hose can be limited in flexible pipe groove by plate；Three current limliting motors 19,20,21 and clamping motor 18 are placed on same level plate,
And respectively there is a pressure head on compression bar head；When work, incubator hose 17 is pressed into current limliting by hose clamping motor 18 first
Then card slot in device version controls three straight-line electric arbors, any one hose conducting and current limliting can be realized.
Claims (1)
1. a kind of big bottled sample liquids automatic subpackaging is set, it is located in isolator, including sample transportation module, sample crawl overturning
Module, syringe needle plug mechanism, peristaltic pump, current-limiting apparatus and incubator operation module, it is characterised in that:
The sample transportation module is mainly made of the belt pulley transport mechanism built on pedestal, and big bottle sample is horizontally placed on appearance
It receives in bracket, the receiving bracket is placed on belt；
The sample crawl flip module is realized by gantry-type mechanical arm, including motor, catching robot and lead screw, gripper
The rotary motion of motor is converted into the grasp force of manipulator by tool hand, and manipulator is realized up and down under the action of motor and lead screw
It is mobile；
The syringe needle plug mechanism, which has, grabs syringe needle manipulator, described to grab syringe needle manipulator and catching robot cooperation completion needle
The plug operation of head, syringe needle are fixed on the fixture that one can mutually be attracted with the calutron grabbed in syringe needle manipulator；Needle
The other end of head is connected to collection bacterium bottle by hose；
It is provided on the hose line of syringe needle to collection bacterium bottle for providing the peristaltic pump and current-limiting apparatus of liquid transfer power；
The current-limiting apparatus includes straight-line electric arbor, servo motor and current limliting slot, and the servo motor is for hose to be pressed into
In current limliting slot, the straight-line electric arbor controls the conducting of current limliting slot inner flexible tube by control extrusion head；
The incubator operation module includes slider-crank mechanism, elevating mechanism and liquid outlet groove, and collection bacterium bottle and its fixture are in song
Vertical position is shifted onto from horizontal position under the action of handle slide block mechanism, and upward, and the fluid hole of bottom of bottle is just for the bottleneck of collection bacterium bottle
Positioned at the surface of liquid outlet groove, the liquid collected in bacterium bottle bottle can be flowed into liquid outlet groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820957411.3U CN208297231U (en) | 2018-06-21 | 2018-06-21 | A kind of big bottled sample liquids automatic subpackaging is set |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820957411.3U CN208297231U (en) | 2018-06-21 | 2018-06-21 | A kind of big bottled sample liquids automatic subpackaging is set |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208297231U true CN208297231U (en) | 2018-12-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820957411.3U Expired - Fee Related CN208297231U (en) | 2018-06-21 | 2018-06-21 | A kind of big bottled sample liquids automatic subpackaging is set |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112226348A (en) * | 2020-10-26 | 2021-01-15 | 达尔文实验机器人成都有限公司 | Bacteria collecting method of microorganism detection robot system applying biomedical injection |
-
2018
- 2018-06-21 CN CN201820957411.3U patent/CN208297231U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112226348A (en) * | 2020-10-26 | 2021-01-15 | 达尔文实验机器人成都有限公司 | Bacteria collecting method of microorganism detection robot system applying biomedical injection |
| CN112226348B (en) * | 2020-10-26 | 2023-06-16 | 达尔文实验机器人成都有限公司 | Bacteria collecting method of microbial detection robot system using biological medicine injection |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181228 Termination date: 20190621 |