CN206188357U - Ampoule sample automatic collection device based on aseptic detection flow - Google Patents
Ampoule sample automatic collection device based on aseptic detection flow Download PDFInfo
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- CN206188357U CN206188357U CN201621192204.0U CN201621192204U CN206188357U CN 206188357 U CN206188357 U CN 206188357U CN 201621192204 U CN201621192204 U CN 201621192204U CN 206188357 U CN206188357 U CN 206188357U
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- ampoule
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- receiving flask
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Abstract
The utility model discloses an ampoule sample automatic collection device based on aseptic detection flow. The utility model relates to a there is special alloy blade to carry out the preliminary treatment to the ampoule, the blade leaves the mar one in the bottleneck department of ampoule, prepare for now cutting the step, adopt a set of form of three mount to fix three ampoule again, it strikes absolutely to use three hammer once to accomplish three ampoule nipple, a serial communication port, after the cutting of accomplishing the ampoule, adopt three injection syringes to utilize the peristaltic pump to absorb the liquid medicine in the ampoule simultaneously, accomplish liquid medicine delivery to the sample enrichment bottle in the process of sample enrichment. The utility model discloses a can one batch collect 30 bottle of medicine liquid, reduced the possibility that the liquid medicine received emery wheel particle and glass's pollution simultaneously. This utility model structure is simple in addition, easy dismounting, and shared space is less, easily realizes the automation mechanized operation.
Description
Technical field
The utility model belongs to food and medicine analysis field, is related to a kind of sample to ampoule bottle to carry out the dress of automatic collection
Put.
Background technology
In recent years, China occurs a lot of food, drug quality security incident so that matter of the government and street levels to food medicine
Amount ensures to pay much attention to.Sterility test as food and medicine quality control key project, in 2010 editions newest GMP《Medicine
Quality of production management regulation》It is proposed with 2015 editions pharmacopeia and is clearly required, is that enterprise and regulator examine to qualified products
The big event tested.Normal sterile checks the laminar flow platform that one-way gas flow is installed in a controlled environment, is put on laminar flow platform
A germ collector is put to complete sterility test.Sterility test instrument contains Sterilized isolator, membrane filtration system（Collection bacterium operation instrument
And Bacteria Incubator）, the part such as microbiological incubator, substitute normal sterile inspection method, there is provided controlled gnotobasis is simultaneously implemented
Steriling test, with integrated level it is high, input cost is low, environment controllability is more preferable the characteristics of, be increasingly taken seriously, obtain extensively
Application cross process automation to realize collection bacterium, improve the efficiency of collection bacterium process.The utility model is for wherein mostly important
The sample ampoules bottle packaging sample of packaging carries out enrichment procedure.Modern ampoule is fired with glass tube, is widely used in Sheng
Put ejection preparation and air high-purity chemical medicine must be completely cut off.The nipple naked light of ampoule encapsulates to completely cut off air, neck part
Mark is indicated, bottleneck can fracture when the pressure is exerted, to extract liquid.In the modern times are medical, first with emery wheel in bottle before opening
Cut is cut out at neck, bottleneck of sterilizing, makes liquid all flow into bottle by nipple upwards, and then bottleneck fractures.It is easy to break
Type ampoule indicates the position that producer cuts in advance at nipple, and nipple directly fractures along these lines.However,
Open ampoule bottle and there is many unsafe factors, for example：Defective ampoule or faulty operation are inducible in unlatching peace
Nipple even bottle is broken into pieces during small jar, causing medical worker to be injured may fall into the liquid polluting glass fragment.Peace
The particulate of glass and emery wheel also results in liquid medicine contamination in small jar opening process.
The content of the invention
The purpose of this utility model is directed to and is installed on the food and medicine sample of ampoule bottle and carries out the automatic richness of quick collection
Acquisition means.
The utility model technical solution adopted for solving the technical problem is：
The utility model includes collecting bottle rack and collection module, cutter sweep module, knocking device module, Ampoule bottle holder
Disk and connecting gear module.
The collecting mechanism includes receiving flask, collection bacterium flexible pipe, peristaltic pump, extraction pin fixture, receiving flask support base, collection
Bottle rack, receiving flask upset motor, rack drives motor, screw mandrel, belt, big belt wheel；Collect bottle rack and be fixed on receiving flask branch
On support base, receiving flask upset motor is fixed on collection bottle rack, and receiving flask is fixed on the rotatable position of collection bottle rack, when
Electric motor starting, it is possible to achieve 360 degree of Arbitrary Rotations；Collection bacterium flexible pipe includes a syringe needle by one end, and other end includes three
The flexible pipe suit composition of individual syringe needle a, needle end inserts receiving flask bottleneck, and three needle ends are placed in extraction fixture, extract fixture
It is placed on screw mandrel, screw mandrel is fixed on limiting plate, the end of screw mandrel is connected by belt with big belt wheel, and big belt wheel is fixed on tooth bar
On motor, tooth bar motor drives big belt wheel to rotate, and is rotated by belt drive screw mandrel, is moved down on realization extraction pin fixture
It is dynamic, opened when ampoule bottle and finished, extract syringe needle fixture and be displaced downwardly in ampoule bottle, peristaltic pump is opened, realize ampoule bottle sample liquids
Extract.
The cutter sweep is made up of cutting rod and corresponding parallel moving mechanism, and cutter sweep is by bottom cutting blade plus side
Face baffle plate is constituted, its lower hollow；The cutting function of cutter sweep is by roller gear, tooth bar, bevel pinion, bevel gear wheel, tooth
The parallel moving mechanism of bar motor composition realizes that rack drives motor is fixed on limiting plate bottom, and bevel gear wheel drives with tooth bar
Dynamic motor is connected, and bevel pinion is engaged by being fixed on motion rod member on limiting plate with bevel gear wheel, and roller gear is fixed on limit
On the plate of position, tooth bar is placed in cutter sweep top, when motor starts, by parallel moving mechanism, it is possible to achieve the transverse direction of tooth bar is come
Return is dynamic, realizes that ampoule bottle cutting pretreatment and ampoule papilla axustica lagenae are reclaimed.
The knocking device includes tapping hammer, connecting rod, taps motor, turnover panel, and three tap hammer and are fixed on by a polished rod
On limiting plate, equipped with motor is tapped, the lower section of polished rod is connecting rod, and connecting rod passes through quadric chain and turnover panel phase for one end of polished rod
Even.
The ampoule bottle pallet and connecting gear module include sample tray and conveyer belt two parts, there is array on pallet
Hole, the inwall of hole posts rubber ring；Conveyer belt is driven by motor, including conveyer belt, and spool, the pallet equipped with sample is placed in
On conveyer belt, the movement of conveyer belt bearing tray.
The beneficial effects of the utility model：The special ampoule bottle-neck that the utility model is used in isolator cuts, oneself
Dynamic opener and the three pin suction methods based on peristaltic pump, specific innovation are mainly reflected in the following aspects：
（1）Need batch to open ampoule bottle for Sterility testing or during making up a prescription and prevent the problem of pollution, using elder generation
Ampoule bottle-neck is pre-processed, is farthest to reduce because cutting disintegrating slag causes pollution；
（2）After need to being taken considerable time using ampoule bottle is cut in batch for ampoule bottle Sample intraocular transfer enrichment,
The three pin suction methods based on peristaltic pump, realize the efficiently concentrating for ampoule bottle sample；
（3）The utility model have simple structure, it is lightweight, be swift in motion, steadily, reliability, energy-conservation and it is free from environmental pollution,
The advantages of easily realizing stepless speed regulation, easily realize overload protection, easily realize complicated action.
Generally speaking, during the utility model largely alleviates Sterility testing, complicated Liquid extracting mistake
Journey and the false positive bacterium that may be caused by maloperation operate, and can effectively improve the function of Sterility testing.
Brief description of the drawings
Fig. 1 the utility model overall construction drawings；
Fig. 2 the utility model cutter sweep module diagrams；
Fig. 3 is the utility model knocking device module diagram；
Fig. 4 is the utility model ampoule bottle pallet schematic diagram；
Fig. 5 is the utility model ampoule bottle connecting gear schematic diagram；
Fig. 6 is the utility model syringe needle connection diagram；
Fig. 7 is limiting plate schematic diagram in the utility model mechanical structure；
Fig. 8 is cutter sweep detailed maps in the utility model mechanical structure；
In figure, 1, receiving flask, 2, collection bacterium flexible pipe, 3, peristaltic pump, 4, ampoule bottle, 5, pallet, 6, cutter sweep, 7, spacing
Plate, 8, extract pin fixture, 9, wheeled support frame, 10, receiving flask support base, 11, collect bottle rack, 12, receiving flask upset
Motor, 13,14,15, roller gear, 16, tooth bar, 17, bevel pinion, 18, bevel gear wheel, 19, rack drives motor, 20, small
Belt wheel, 21, belt, 22, big belt wheel, 23, tap motor, 24, tap hammer, 25, polished rod, 26, turnover panel, 27, connecting rod, 28, transmission
Band, 29,30, spool, 31 3 pin draw-out devices.
Specific embodiment
Below by drawings and Examples, the technical solution of the utility model is described in further detail.
As shown in Figure 1, Figure 2 and Figure 3, integral mechanical structure mainly includes：Collect bottle rack and collection module, cutter sweep
Module, knocking device module, ampoule bottle pallet and connecting gear module are constituted, wherein：
Buffering bottle rack and collecting mechanism include receiving flask 1, collection bacterium flexible pipe 2, peristaltic pump 3, extract pin fixture 8, receiving flask
Support base 10, collection bottle rack 11, receiving flask upset motor 12, rack drives motor 19, screw mandrel 20, belt 21, big belt wheel
22。
Concrete structure：Collect bottle rack 11 to be fixed in receiving flask support base 10, receiving flask upset motor 12 is fixed on
Collect on bottle rack 11, receiving flask 1 is fixed on the rotatable position of collection bottle rack, works as electric motor starting, it is possible to achieve 360 degree any
Angle rotates, and collection bacterium flexible pipe 2 includes a syringe needle by one end, and other end includes three flexible pipe suit compositions of syringe needle, work
When, a needle end inserts receiving flask bottleneck, and three needle ends are placed in extraction fixture 8, and middle one point of three joint area snaps in compacted
Dynamic pump, extracts fixture 8 and is placed on screw mandrel 20, and screw mandrel 20 is fixed on limiting plate 7, and the end of screw mandrel passes through belt 21 and big belt wheel
22 connections, big belt wheel 22 is fixed on rack drives motor 19, and tooth bar motor 19 drives big belt wheel 22 to rotate, by the band of belt 21
Dynamic screw mandrel 20 is rotated, and realizes extracting moving up and down for pin fixture 8, is opened when ampoule bottle and finished, and is extracted syringe needle fixture 8 and is displaced downwardly to peace
In small jar bottle 4, peristaltic pump 3 is opened, empty surge flask air, form negative pressure, realize that ampoule bottle sample liquids are extracted.
Cutter sweep module includes：Cutter sweep 6, roller gear 13,14,15, tooth bar 16, bevel pinion 17, auger tooth
Wheel 18, rack drives motor 19.
Concrete structure：Cutter sweep module is made up of cutter sweep and corresponding motion, and cutter sweep 6 is by bottom
Cutting blade adds side board to constitute, and its lower hollow, tooth bar 16 is fixed on cutter sweep 6；Rack drives motor 19 is fixed
In the bottom of limiting plate 7, bevel gear wheel 18 is connected with rack drives motor 19, and bevel pinion 17 is transported by being fixed on limiting plate 7
Lever part is engaged with bevel gear wheel 18, and roller gear is fixed on limiting plate 7, when rack drives motor 19 starts, by auger
Gear 18, bevel pinion 17, roller gear 13,14,15 and tooth bar 16 can realize being moved back and forth for tooth bar, realize ampoule
Bottle cutting pretreatment and ampoule papilla axustica lagenae are reclaimed.
Knocking device module includes：Limiting plate 7, taps motor 23, taps hammer 24, polished rod 25, turnover panel 26, connecting rod 27.
Concrete structure：Tap motor 24 to be fixed on limiting plate 7 by polished rod 26, three tap hammer 25 and are fixed on polished rod 26
On, connecting rod 27 is placed on limiting plate 7, can be rotated, and turnover panel 26 is fixed on connecting rod, after cutting module end-of-job, is installed
Percussion motor 23 in the side of limiting plate 7 starts, and drives three to tap hammer 25 and taps three ampoule bottles simultaneously, by ampoule papilla axustica lagenae
Remove down.Afterwards, tap motor 23 to be rotated further, percussion is hammered the beam contact of 25 and connecting rod 27 into shape, and cross bar is lifted.Cross bar with
Quadric chain is linked, and turnover panel 26 is lifted, and nipple is fallen into the collecting tank of move portion, and is moved into nipple by move portion useless
In product collecting box.
Ampoule bottle pallet and connecting gear module include：Pallet 5, wheeled support frame 9, conveyer belt 28, spool 29,30.
Concrete structure：There are 3*10 totally 30 holes on pallet 5, the inwall in hole posts rubber ring, playing prevents ampoule bottle from turning
Dynamic effect, ampoule bottle 4 is placed in pallet 5, and pallet 5 is placed on conveyer belt 28, and conveyer belt 28 is supported by spool 29,30, spool
It is placed on wheeled support frame 28.The ampoule bottle that will be equipped with measuring samples 4 is needed to insert pallet before the Sterility testing for carrying out sample
In hole on 5, the pallet 5 that will be equipped with sample is placed on conveyer belt 29, conveyer belt 29 can bearing tray movement, sample 4 is defeated
Delivering to subsequent module carries out example enrichment work.
The embrittlement of bottle is easily caused during the unlatching of ampoule bottle, causes the splashing of sample, therefore will be to ampoule bottle-neck position
Pre-processed, then could be carried out operation of breakage to it.During being pre-processed to ampoule bottle, to ampoule bottle-neck
Core technology of the present utility model when the mechanism for carrying out surface trimming pretreatment designs, when ampoule bottle is sent to specified location,
With a sharp blade, 3 bottles of transversely arranged ampoule bottles are once cut, current depth of cut is not deep, simply marks
One cut, in order to when hand hammer hammer action is carried out, efficiently and effectively complete ampoule bottle unlatching work.After cutting terminates,
Installed in the percussion electric motor starting of main chamber body side surface, drive three to tap hammer and tap three ampoule bottles simultaneously, by ampoule papilla axustica lagenae
Remove down.Afterwards, the motor is rotated further, and makes the beam contact of percussion hammer and front, and cross bar is lifted.Cross bar and double leval jib machine
Structure is linked, and turnover panel is lifted, and nipple is fallen into the collecting tank of move portion, and nipple is moved into waste collection case by move portion
In.
By the automatic enrichment procedure to ampoule bottle sample, also dropped simultaneously in the raising for improving sterility test efficiency accuracy rate
It is low in the past due to human users are lack of standardization or human error caused by sterility test sample bacterium long situation, reduce enterprise
The expenditure of the aspects such as duplicate detection, the analysis of causes, with important practical significance.
To sum up, the utility model devises special metals blade and ampoule bottle is pre-processed, bottle of the blade in ampoule bottle
One cut is left at neck, is prepared to cut below step, then three ampoules are fixed in the form of three one group of fixed mounts
Bottle, once three ampoule papilla axustica lagenaes of completion are knocked off to tap hammer using three, and are removed broken glass by special mechanism, are completed
After the cutting of ampoule bottle, while liquid is delivered into sample using the liquid in peristaltic pump ampoule bottle using three injection-tubes
The process of example enrichment is completed in product enrichment bottle.The utility model can be collected with a batch to 30 bottle liquid medicines, while drop
Low liquid is subject to the possibility of the pollution of emery wheel particulate and glass.The other utility model simple structure, convenient disassembly is shared
Space is smaller, it is easy to accomplish automation mechanized operation.
Claims (1)
1. the ampoule bottle sample automatic collecting device based on Sterility testing flow, including collection bottle rack and collection module, cutting
Apparatus module, knocking device module, ampoule bottle pallet and connecting gear module, it is characterised in that：
The collecting mechanism includes receiving flask, collection bacterium flexible pipe, peristaltic pump, extraction pin fixture, receiving flask support base, receiving flask branch
Frame, receiving flask upset motor, rack drives motor, screw mandrel, belt, big belt wheel；Collect bottle rack and be fixed on receiving flask support bottom
On seat, receiving flask upset motor is fixed on collection bottle rack, and receiving flask is fixed on the rotatable position of collection bottle rack, works as motor
Start, it is possible to achieve 360 degree of Arbitrary Rotations；Collection bacterium flexible pipe includes a syringe needle by one end, and other end includes three pins
The flexible pipe suit composition of head a, needle end inserts receiving flask bottleneck, and three needle ends are placed in extraction fixture, extract fixture and are placed in
On screw mandrel, screw mandrel is fixed on limiting plate, and the end of screw mandrel is connected by belt with big belt wheel, and big belt wheel is fixed on rack drives
On motor, tooth bar motor drives big belt wheel to rotate, and is rotated by belt drive screw mandrel, realizes extracting moving up and down for pin fixture,
Opened when ampoule bottle and finished, extracted syringe needle fixture and be displaced downwardly in ampoule bottle, open peristaltic pump, realize that ampoule bottle sample liquids are taken out
Take；
The cutter sweep is made up of cutting rod and corresponding parallel moving mechanism, and cutter sweep adds side board by bottom cutting blade
Constitute, its lower hollow；The cutting function of cutter sweep is by roller gear, tooth bar, bevel pinion, bevel gear wheel, rack drives
The parallel moving mechanism of motor composition realizes that rack drives motor is fixed on limiting plate bottom, bevel gear wheel and rack drives motors
It is connected, bevel pinion is engaged by being fixed on motion rod member on limiting plate with bevel gear wheel, and roller gear is fixed on limiting plate,
Tooth bar is placed in cutter sweep top, when motor starts, by parallel moving mechanism, realizes being moved back and forth for tooth bar, completes
Ampoule bottle cutting pretreatment and ampoule papilla axustica lagenae are reclaimed；
The knocking device include tap hammer, connecting rod, tap motor, turnover panel, three tap hammer into shape be fixed on by a polished rod it is spacing
On plate, equipped with motor is tapped, the lower section of polished rod is connecting rod, and connecting rod is connected by quadric chain with turnover panel for one end of polished rod；
The ampoule bottle pallet and connecting gear module include sample tray and conveyer belt two parts, there is array hole on pallet
Hole, the inwall of hole posts rubber ring；Conveyer belt is driven by motor, including conveyer belt, and spool, the pallet equipped with sample is placed in biography
Send and take, the movement of conveyer belt bearing tray.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621192204.0U CN206188357U (en) | 2016-11-06 | 2016-11-06 | Ampoule sample automatic collection device based on aseptic detection flow |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621192204.0U CN206188357U (en) | 2016-11-06 | 2016-11-06 | Ampoule sample automatic collection device based on aseptic detection flow |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206188357U true CN206188357U (en) | 2017-05-24 |
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ID=58733843
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| CN201621192204.0U Active CN206188357U (en) | 2016-11-06 | 2016-11-06 | Ampoule sample automatic collection device based on aseptic detection flow |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109226130A (en) * | 2018-09-26 | 2019-01-18 | 广州珂诚包装技术有限公司 | A kind of composite soft tube impurity cleaning device |
| CN111896760A (en) * | 2020-07-15 | 2020-11-06 | 宁波华仪宁创智能科技有限公司 | Control method of closed space and automatic sample introduction method |
| CN112141980A (en) * | 2020-10-22 | 2020-12-29 | 溧阳市人民医院 | Automatic ampoule opener |
-
2016
- 2016-11-06 CN CN201621192204.0U patent/CN206188357U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109226130A (en) * | 2018-09-26 | 2019-01-18 | 广州珂诚包装技术有限公司 | A kind of composite soft tube impurity cleaning device |
| CN111896760A (en) * | 2020-07-15 | 2020-11-06 | 宁波华仪宁创智能科技有限公司 | Control method of closed space and automatic sample introduction method |
| CN112141980A (en) * | 2020-10-22 | 2020-12-29 | 溧阳市人民医院 | Automatic ampoule opener |
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