CN207877750U - A kind of portable nucleic acid extraction magnetic frame - Google Patents
A kind of portable nucleic acid extraction magnetic frame Download PDFInfo
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- CN207877750U CN207877750U CN201820142239.6U CN201820142239U CN207877750U CN 207877750 U CN207877750 U CN 207877750U CN 201820142239 U CN201820142239 U CN 201820142239U CN 207877750 U CN207877750 U CN 207877750U
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- nucleic acid
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- acid extraction
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Abstract
The utility model discloses a kind of portable nucleic acid extraction magnetic frames, including the bottom plate and top plate being mutually parallel, the front and rear panels being mutually parallel are erected between bottom plate and top plate, it is additionally provided with the middle connecting plate that both ends are separately connected front and rear panels, the both sides of middle connecting plate are equipped with several magnetic devices being from top to bottom vertically arranged, the both ends of top plate and the both sides of foreboard are equipped with several through-holes for placing response pipe, fixing slot corresponding with lead to the hole site is equipped on bottom plate and back plate, when reaction tube is placed from the through-hole on top plate, it can be by stronger magnetic force, the sample larger suitable for volume, when reaction tube is placed from the through-hole on foreboard, the magnetic force being subject to is smaller, sample suitable for small volume, selection is carried out to placement location according to different sample volumes and improves adsorption efficiency, this utility model is used for Bioexperiment clothing arts.
Description
Technical field
The utility model is related to Bioexperiment clothing arts, more particularly to a kind of portable nucleic acid extraction magnetic frame.
Background technology
Paramagnetic particle method extract nucleic acid, be with nanotechnology to the surface of superparamagnetic nano particle carry out improve and surface repair
After decorations, it is prepared into superparamagnetism silica nanometer magnetic bead, can specifically be identified with nucleic acid molecules on micro interface and efficiently
In conjunction with.It, can be from blood, animal tissue, food under the action of salt and externally-applied magnetic field using the superparamagnetism of silica nanoparticle
Isolate DNA and RNA in product, pathogenic microorganism equal samples, can be applicable to clinical disease diagnosis, transfusion safety, Forensic Identification,
The multiple fields such as environmental microorganism detection, food safety detection, molecular biology research.
Paramagnetic particle method nucleic acid extraction can be generally divided into four steps:Sample cracks --- nucleic acid specificity is attached on magnetic bead ---
The washing of magnetic bead and nucleic acid conjugates --- nucleic acid is eluted from magnetic bead and is detached.
In general, the washing needs of magnetic bead and nucleic acid conjugates are adsorbed magnetic bead using external magnetic.And according to cracking
The washing of the difference of sample size, magnetic bead and nucleic acid conjugates can carry out in different size reaction tube.But it is existing on the market
Magnetic frame specification is mostly between 1.5~2mL, and the position provided with multiple placing response pipes so that volume is larger, carries not
Just.And the sample of large volume is carried out there is still a need for multiplicating after packing, it is time-consuming and laborious.
Utility model content
The purpose of this utility model is to provide a kind of high portable nucleic acid extraction magnetic frames of adsorption efficiency.
Technical solution adopted in the utility model is：
A kind of portable nucleic acid extraction magnetic frame, including the bottom plate and top plate that are mutually parallel, erect between bottom plate and top plate
The front and rear panels being mutually parallel, are additionally provided with the middle connecting plate that both ends are separately connected front and rear panels, and the both sides of middle connecting plate are equipped with
Several magnetic devices, several magnetic devices are from top to bottom vertically arranged, and the both ends of top plate and the both sides of foreboard are equipped with several use
In the through-hole of placing response pipe, fixing slot corresponding with lead to the hole site is equipped on bottom plate and back plate.
It is further used as the improvement of technical solutions of the utility model, the both ends on top plate are arranged symmetrically, and there are two through-holes, preceding
The both sides of plate are respectively provided with an exhausting hole, and the diameter of each exhausting hole is different, and the diameter of through-hole on the top is arranged with setting preceding
The diameter of through-hole on plate is different.
It is further used as the improvement of technical solutions of the utility model, magnetic devices are several cylindrical magnetic stripes, each magnetic dress
It sets and extends transversely through middle connecting plate.
Be further used as the improvement of technical solutions of the utility model, magnetic devices altogether there are five, five magnetic devices are vertical
Middle connecting plate is arranged in close to the side of back plate.
It is further used as the improvement of technical solutions of the utility model, magnetic devices are detachably fixed with middle connecting plate and connect, in
Connecting plate is equipped with several mounting holes for installing magnetic devices, and the both ends of each mounting hole are equipped with flexible fixing piece.
It is further used as the improvement of technical solutions of the utility model, the often end of each mounting hole is all provided with there are four fixing piece, and four
A fixing piece is circumferentially angularly distributed around the central shaft of mounting hole.
It is further used as the improvement of technical solutions of the utility model, the open end of each fixing slot is equipped with consolidating of being auxiliarily fixed
Fixed circle.
The beneficial effects of the utility model：This portable nucleic acid extraction magnetic frame, is equipped in top plate and foreboard for putting
The through-hole of reaction tube is set, and magnetic devices are vertically arranged in the both sides of middle connecting plate, when reaction tube is placed from the through-hole on top plate
When, the larger sample of volume can be suitable for by stronger magnetic force, when reaction tube is placed from the through-hole on foreboard, be subject to
Magnetic force is smaller, is suitable for the sample of small volume, and carrying out selection to placement location according to different sample volumes improves absorption effect
Rate.
Description of the drawings
The utility model is described in further detail below in conjunction with the accompanying drawings：
Fig. 1 is the overall structure diagram of the utility model embodiment；
Fig. 2 is the left view of the utility model embodiment；
Fig. 3 is the magnetic devices mounting structure schematic diagram of the utility model embodiment.
Specific implementation mode
Referring to Fig.1~Fig. 3, the utility model are a kind of portable nucleic acid extraction magnetic frame, including the bottom plate 1 being mutually parallel
With top plate 2, the foreboard 3 being mutually parallel and back plate 4 are erected between bottom plate 1 and top plate 2, are additionally provided with both ends and are separately connected 3 He of foreboard
The both sides of the middle connecting plate 5 of back plate 4, middle connecting plate 5 are equipped with several magnetic devices 6, and several magnetic devices 6 are vertical from top to bottom to be arranged
Row, the both ends of top plate 2 and the both sides of foreboard 3 are equipped with several through-holes 7 for placing response pipe, are all provided in bottom plate 1 and back plate 4
There is fixing slot corresponding with 7 position of through-hole 8.
Specifically, in practical operation, the placement location of reaction tube can be selected according to the volume of sample.Work as sample
Volume it is larger when, reaction tube can be stretched to the bottom of reaction tube from the through-hole 7 of top plate 2 and fixing slot 8 on bottom plate 1 coordinates,
For reaction tube by the magnetic force of all magnetic devices 6 arranged from side vertical, the interior magnetic bead contained of reaction tube will be by magnetic at this time
Property device 6 attract and be fixed on tube wall, the nucleic acid being adsorbed on magnetic bead will also be fixed therewith, at this time by other in reaction tube
Substance backward walking, you can realize the separation of nucleic acid.
When the small volume of sample, then excessive magnetic force is not needed, therefore reaction tube can be set from the through-hole 7 of foreboard 3
Enter to fixing slot 8 on the bottom of reaction tube and back plate 4 and coordinate, reaction tube will be by the magnetic devices of the part from side at this time
6 magnetic force.And more reaction tubes can be placed on foreboard 3 simultaneously, to improve the efficiency of experiment.
As the utility model preferred embodiment, the both ends on top plate 2 are symmetrical arranged there are two through-hole 7, foreboard 3
Both sides are respectively provided with an exhausting hole 7, and the diameter of each exhausting hole 7 is different, and the diameter of through-hole 7 on the top is arranged and is arranged in foreboard
The diameter of through-hole 7 on 3 is different, and the different through-hole 7 of diameter is applicable to the reaction tube of different-diameter, can be according to actual use feelings
Condition is selected.
As the utility model preferred embodiment, magnetic devices 6 are several cylindrical magnetic stripes, and each magnetic devices 6 are equal
Middle connecting plate 5 is extended transversely through, most of structure of magnetic devices 6 is located among middle connecting plate 5, avoids getting rusty, prolong the service life.
As the utility model preferred embodiment, magnetic devices 6 altogether there are five, five magnetic devices 6 are vertically arranged
In middle connecting plate 5 close to the side of back plate 4, when reaction tube is stretched into from foreboard 3, the position of magnetic devices 6 will be relatively close to reaction
The bottom of pipe, convenient for the magnetic bead absorption in reaction bottom of the tube that will sink.
As the utility model preferred embodiment, magnetic devices 6 are detachably fixed with middle connecting plate 5 and connect, middle connecting plate 5
Several mounting holes for installing magnetic devices 6 are equipped with, the both ends of each mounting hole are equipped with flexible fixing piece, this is solid
Determining part structure allows magnetic devices 6 to dismantle and can be adjusted to the extension elongation of magnetic devices 6 according to use demand, with
Just the size of magnetic force is controlled.
As the utility model preferred embodiment, the often end of each mounting hole is all provided with that there are four fixing piece 9, four fixations
Part 9 is circumferentially angularly distributed around the central shaft of mounting hole, ensure that the firm of magnetic devices 6.
As the utility model preferred embodiment, the open end of each fixing slot 8 is equipped with the retainer plate being auxiliarily fixed,
So that the tube bottom placement of reaction tube is more steady.
This portable nucleic acid extraction magnetic frame is suitable for the sample of different volumes by placing response pipe from different directions
Demand, and improve the efficiency of experiment.Simultaneously as the through-hole 7 with different-diameter, therefore adapt to the reaction of plurality of specifications
Pipe, has widened the scope of application.And the adjustability of magnetic devices 6 makes the operation of experiment more careful, experiment effect is more preferable.
Certainly, the invention is not limited to the above embodiment, and those skilled in the art are without prejudice to originally
Equivalent variations or replacement can be also made under the premise of utility model spirit, these equivalent modifications or replacement are all contained in the application
In claim limited range.
Claims (7)
1. a kind of portable nucleic acid extraction magnetic frame, it is characterised in that：It is described including the bottom plate (1) being mutually parallel and top plate (2)
The foreboard (3) being mutually parallel and back plate (4) are erected between bottom plate (1) and top plate (2), are additionally provided with both ends and are separately connected the foreboard
(3) and the middle connecting plate of back plate (4) (5), the both sides of the middle connecting plate (5) are equipped with several magnetic devices (6), several magnetism
Device (6) is from top to bottom vertically arranged, and the both ends of the top plate (2) and the both sides of foreboard (3) are equipped with several anti-for placing
Should pipe through-hole (7), be equipped with fixing slot (8) corresponding with the through-hole (7) position on the bottom plate (1) and back plate (4).
2. portable nucleic acid extraction magnetic frame according to claim 1, it is characterised in that：Both ends on the top plate (2)
The through-hole (7) there are two being symmetrical arranged, the both sides of the foreboard (3) are respectively provided with through-hole (7) described in a row, respectively arrange the through-hole
(7) diameter is different, and the diameter of the through-hole on the top (7) and the through-hole (7) being arranged on the foreboard (3) is arranged
Diameter is different.
3. portable nucleic acid extraction magnetic frame according to claim 1, it is characterised in that：The magnetic devices (6) are if be
Dry cylinder magnetic stripe, each magnetic devices (6) extend transversely through the middle connecting plate (5).
4. portable nucleic acid extraction magnetic frame according to claim 3, it is characterised in that：The magnetic devices (6) are shared
Five, five magnetic devices (6) are vertically arranged the side close to the back plate (4) in the middle connecting plate (5).
5. portable nucleic acid extraction magnetic frame according to claim 4, it is characterised in that：The magnetic devices (6) and institute
It states middle connecting plate (5) and is detachably fixed connection, the middle connecting plate (5) is equipped with several peaces for installing the magnetic devices (6)
Hole is filled, the both ends of each mounting hole are equipped with flexible fixing piece (9).
6. portable nucleic acid extraction magnetic frame according to claim 5, it is characterised in that：The often end of each mounting hole is equal
If there are four the fixing piece (9), four fixing pieces (9) are circumferentially angularly distributed around the central shaft of the mounting hole.
7. portable nucleic acid extraction magnetic frame according to claim 1, it is characterised in that：Each the fixing slot (8) are opened
Mouth end is equipped with the retainer plate being auxiliarily fixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820142239.6U CN207877750U (en) | 2018-01-26 | 2018-01-26 | A kind of portable nucleic acid extraction magnetic frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820142239.6U CN207877750U (en) | 2018-01-26 | 2018-01-26 | A kind of portable nucleic acid extraction magnetic frame |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207877750U true CN207877750U (en) | 2018-09-18 |
Family
ID=63508735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820142239.6U Active CN207877750U (en) | 2018-01-26 | 2018-01-26 | A kind of portable nucleic acid extraction magnetic frame |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207877750U (en) |
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2018
- 2018-01-26 CN CN201820142239.6U patent/CN207877750U/en active Active
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