CN219930025U - Multipurpose magnetic rack - Google Patents
Multipurpose magnetic rack Download PDFInfo
- Publication number
- CN219930025U CN219930025U CN202320783747.3U CN202320783747U CN219930025U CN 219930025 U CN219930025 U CN 219930025U CN 202320783747 U CN202320783747 U CN 202320783747U CN 219930025 U CN219930025 U CN 219930025U
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- Prior art keywords
- centrifuge tube
- supporting seat
- tube placing
- magnet
- opening
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- 210000001503 joint Anatomy 0.000 claims abstract description 14
- 239000000758 substrate Substances 0.000 claims abstract description 8
- 229910000838 Al alloy Inorganic materials 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 claims description 4
- 229910001172 neodymium magnet Inorganic materials 0.000 claims description 4
- 230000006872 improvement Effects 0.000 abstract description 3
- 239000011324 bead Substances 0.000 description 11
- 238000009434 installation Methods 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 239000012620 biological material Substances 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
Abstract
The present utility model relates to the field of medical devices. The multipurpose magnetic rack comprises a magnetic rack substrate, wherein the magnetic rack substrate comprises a supporting seat, two rows of centrifuge tube placing holes which are arranged front and back are formed in the supporting seat, an opening is formed in one side of the centrifuge tube placing hole in the radial direction, and the opening is positioned on the side wall of the supporting seat; the inner diameter of the centrifuge tube placing hole at the front side is different from that of the centrifuge tube placing hole at the rear side; each centrifuge tube placing hole is in butt joint and conduction with a mounting groove for placing a magnet, and the magnet is arranged in the mounting groove; the bottom of the supporting seat is provided with a front extending part extending forwards and a rear extending part extending backwards, and a limiting groove with an opening at the lower end is arranged between the front extending part and the rear extending part. According to the centrifuge tube, the centrifuge tube placing hole is optimized to be in an open form, so that the occupied volume is reduced under the condition of ensuring the strength as much as possible. Through the setting of the centrifuging tube placing hole of different internal diameters, great improvement the compatibility of device.
Description
Technical Field
The utility model relates to the field of medical instruments, in particular to a body position protection device.
Background
The principle of extracting nucleic acid by a magnetic bead method is that the superparamagnetism silicon oxide nanometer magnetic bead is prepared by modifying and surface-modifying the surface of superparamagnetism nanometer particles by a nanometer technology. The magnetic beads can be specifically identified and efficiently combined with nucleic acid molecules on a microscopic interface. Under the action of hydrochloric acid, isothiocyanate, etc. and external magnetic field, the superparamagnetism nano magnetic beads can separate out nucleic acid from blood, animal tissue, food, pathogenic microbe, etc. The method is widely applied to a plurality of fields such as clinical disease diagnosis, forensic identification, environmental microorganism detection, molecular biology research and the like.
In the current process of extracting nucleic acid by using a magnetic bead method, the magnetic field is usually cited by a magnetic frame to capture the magnetic bead.
The existing magnetic force frame has the following defects:
1) The centrifuge tube placing hole on the existing magnetic rack is often in a closed round hole form (such as a magnetic rack for enriching nucleic acid by a magnetic bead method in aerosol disclosed in publication No. CN 216972486U), and the magnetic rack adopting the round hole causes overlarge volume of the magnetic rack and occupies valuable equipment internal space.
2) Most of the magnetic force frames are only suitable for single-volume pipes, and are not beneficial to being used in environments compatible with pipes with various volumes.
3) The sliding of the installation structure of the existing magnetic frame is one of installation modes, such as a modularized eight-connecting-tube magnetic frame, a modularized support base and a modularized eight-connecting-tube magnetic frame disclosed by publication No. CN 207456907U. But to slidable mounting's magnetic frame, under high flux operation, mechanical vibration and the touching of arm can produce the problem of offset, need carry out the arm calibration often, reduced equipment operating efficiency, can lead to the magnetic bead disturbance simultaneously, influence follow-up experimental operation, reduce the repeatability scheduling problem of production experiment.
Disclosure of Invention
The present utility model has been made to solve the above-mentioned at least one technical problem, and provides a multipurpose magnetic rack.
The technical scheme of the utility model is as follows: the multipurpose magnetic rack comprises a magnetic rack substrate, wherein the magnetic rack substrate comprises a supporting seat, and is characterized in that two rows of centrifuge tube placing holes which are arranged front and back are formed in the supporting seat, an opening is formed in one side of the centrifuge tube placing holes in the radial direction, and the opening is positioned on the side wall of the supporting seat;
the inner diameter of the centrifuge tube placing hole at the front side is different from that of the centrifuge tube placing hole at the rear side;
each centrifuge tube placing hole is in butt joint and conduction with a mounting groove for placing a magnet, and the magnet is arranged in the mounting groove;
the bottom of the supporting seat is provided with a front extending part extending forwards and a rear extending part extending backwards, and a limiting groove with an opening at the lower end is formed between the front extending part and the rear extending part.
According to the centrifuge tube, the centrifuge tube placing hole is optimized to be in an open form, so that the occupied volume is reduced under the condition of ensuring the strength as much as possible. Through the setting of the centrifuging tube placing hole of different internal diameters, great improvement the compatibility of device. The magnetic force frame deflection caused by vibration is solved through the combination of the front extension part, the rear extension part and the limiting groove. After the supporting seat slides into the installation chute through the front extension part and the rear extension part, the limiting block lifted from bottom to top is inserted into the limiting groove, so that the longitudinal limiting of the magnetic frame is realized.
Further preferably, the opening direction of the mounting groove is directed toward the centrifuge tube placement hole and toward the side of the opening of the adjacent centrifuge tube placement hole.
Further preferably, the opening end of the mounting groove is in butt joint and conduction with an imbedding port for mounting the magnet, and one side of the imbedding port, which is far away from the mounting groove, is positioned on the side wall of the supporting seat;
the opening is in butt joint and conduction with the imbedding opening.
The magnet is convenient to install through the open side of centrifuging tube place hole.
Further preferably, the magnet is connected with the mounting groove in an interference fit manner.
Is convenient for installation.
Further preferably, the central angle of the centrifuge tube placement hole is more than 270 degrees and less than 360 degrees.
Further preferably, the tops of the front side and the rear side of the supporting seat are provided with protrusions extending outwards, the tops of the protrusions are flush with the top of the supporting seat, and gaps between adjacent protrusions are opposite to openings of adjacent centrifuge tube placing holes;
the protrusion distance of the front side of the supporting seat is different from the protrusion distance of the rear side of the supporting seat.
The positioning structure is convenient for sliding into the equipment as a magnetic rack through the bulge. The distance between adjacent bulges is used for knowing whether the magnetic force frame slides into the large hole side or the small hole side, so that the positioning of the front side and the rear side of the magnetic force frame is facilitated.
Further preferably, the support seat comprises an upper part, a middle part and a lower part which are arranged from top to bottom;
the lower portion is provided with the front extension and the rear extension;
the front side and the rear side of the middle part are both inwards contracted at the upper part and the lower part;
the central angle of the centrifuge tube placing hole positioned at the upper part is larger than the central angle of the centrifuge tube placing hole positioned at the middle part.
Further preferably, the upper portion is provided with the projection.
Further improve the stability of putting in centrifuging tube place the hole.
Further preferably, the number of centrifuge tube placement holes on any one of the front and rear sides of the support seat is twice the number of centrifuge tube placement holes on the other side.
Further preferably, the centrifuge tube placement holes on the front side and the rear side of the support seat are different in number;
and the centrifuge tube placing holes on one side with less centrifuge tube placing holes are arranged in a left-right mirror symmetry manner on the supporting seat, and the center of the left-right direction on one side with less centrifuge tube placing holes is provided with a positioning bulge on the supporting seat.
The positioning of the central position of the magnetic rack in the left-right direction is convenient.
Further preferably, both ends all run through to the lateral wall of magnetic force frame in limit groove.
Is convenient for saving materials and reducing dead weight.
Further preferably, the magnet is an N52 strength neodymium iron boron permanent magnet.
The magnetic field intensity is high, the magnetic beads can be gathered efficiently, and the separation of nucleic acid and waste liquid is facilitated. Meanwhile, heat generated by electrifying the electromagnet in the extraction process is avoided, and the damage to biological materials is less.
Further preferably, the material of the supporting seat is aviation aluminum alloy. The aviation aluminum alloy material reduces the occupied volume under the condition of keeping the strength of the frame body as much as possible.
The beneficial effects are that:
1) The utility model provides a small-volume compatible magnetic rack which can be used for automatic nucleic acid extraction.
2) The aviation aluminum alloy base has the advantages of high strength, high toughness and high corrosion resistance, and can effectively resist pressure, impact force and corrosion in the experimental process.
3) The front extension part, the rear extension part and the limiting groove are convenient for fixing the corresponding positions of the insertion equipment, and cannot easily generate position deviation due to mechanical vibration.
4) The magnet adopts N52 intensity neodymium-iron-boron permanent magnet, and the magnetic field intensity is big, can high-efficient gathering magnetic bead, makes things convenient for the separation of nucleic acid and waste liquid.
5) The magnetic rack adopts an open design, so that the magnetic rack can be suitable for consumable materials of different systems, and the use efficiency of the magnetic rack is improved.
The utility model has reliable use and easy installation, solves the problems that the prior magnetic rack has overlarge volume and occupies precious equipment internal space, the magnetic rack is mostly a single-volume pipe which is a single magnetic rack, is not beneficial to being compatible with various consumables, and can generate position deviation due to mechanical vibration and mechanical arm touch under high-flux operation working conditions, is suitable for automatic warehouse building equipment, can effectively improve the compatibility and the working efficiency of the automatic warehouse building equipment, and improves the stability of the structure of the warehouse building equipment.
Drawings
FIG. 1 is a schematic structural view of embodiment 1 of the present utility model;
FIG. 2 is a rear view of embodiment 1 of the present utility model;
FIG. 3 is a front view of embodiment 1 of the present utility model;
fig. 4 is a right side view of embodiment 1 of the present utility model.
In the figure: 1 is a supporting seat, 2 is a first magnet, 3 is a second magnet, 4 is a rear hole, 5 is a front hole, 6 is a limit groove, 7 is a front extension part, 8 is a rear extension part,
Detailed Description
The utility model is further described below with reference to the accompanying drawings.
Referring to fig. 1 to 4, embodiment 1, a multipurpose magnetic rack, comprising a magnetic rack substrate, wherein the magnetic rack substrate comprises a support base 1, two rows of centrifuge tube placing holes arranged front and back are formed in the support base 1, an opening is formed in one side of the centrifuge tube placing hole in the radial direction, and the opening is positioned on the side wall of the support base 1; and the inner diameter of the centrifuge tube placing hole (front hole 5) at the front side is different from the inner diameter of the centrifuge tube placing hole (rear hole 4) at the rear side; each centrifuge tube placing hole is in butt joint and conduction with a mounting groove for placing a magnet, and the magnet is arranged in the mounting groove; the bottom of the supporting seat 1 is provided with a front extension part 7 extending forwards and a rear extension part 8 extending backwards, and a limit groove 6 with an opening at the lower end is arranged between the front extension part 7 and the rear extension part 8. Both ends all run through to the lateral wall of magnetic force frame about spacing groove 6. According to the centrifuge tube, the centrifuge tube placing hole is optimized to be in an open form, so that the occupied volume is reduced under the condition of ensuring the strength as much as possible. Through the setting of the centrifuging tube placing hole of different internal diameters, great improvement the compatibility of device. The magnetic frame deflection caused by vibration is solved by the combination of the front extension part 7, the rear extension part 8 and the limit groove 6. After the supporting seat 1 slides into the installation chute through the front extension part 7 and the rear extension part 8, the limiting block lifted from bottom to top is inserted into the limiting groove 6, so that the longitudinal limiting of the magnetic frame is realized. The limiting block can be a telescopic rod of the lifting cylinder. Of course, the lifting device can also be a limiting block connected with a telescopic rod of the lifting cylinder.
The centrifuge tube placement hole on the front side is used as a front hole 5, and the centrifuge tube placement hole on the rear side is used as a rear hole 4, as shown in fig. 1, wherein the inner diameter of the front hole is larger than that of the rear hole. The inner diameter of the front hole may be smaller than the inner diameter of the rear hole.
The outer diameter of the installation groove for butt joint of centrifuge tube placing holes with large aperture in the centrifuge tube placing holes on the front side and the rear side is larger than that of the installation groove for butt joint of centrifuge tube placing holes with small aperture. The first magnet 2 is arranged in the mounting groove communicated with the front hole, and the second magnet 3 is arranged in the mounting groove communicated with the rear hole. The outer diameter of the first magnet is larger than that of the second magnet.
The opening direction of the mounting groove faces the centrifuge tube placing hole and faces one side of the opening of the adjacent centrifuge tube placing hole. The opening end of the mounting groove is in butt joint and conduction with an imbedding port for mounting the magnet, and one side of the imbedding port, which is far away from the mounting groove, is positioned on the side wall of the supporting seat; the opening is in butt joint and conduction with the imbedding opening. The magnet is convenient to install through the open side of centrifuging tube place hole. The magnet is connected with the mounting groove in an interference fit manner. Is convenient for installation.
The central angle of the centrifuge tube placing hole is larger than 270 degrees and smaller than 360 degrees. The centrifuging tube is placed the hole and is included upper portion and the lower part that set up from top to bottom, and the inner wall of upper portion is the face of cylinder. The inner wall of the lower part is conical with wide upper part and narrow lower part. The mounting groove is in butt joint and conduction with the lower part. The lower part is in butt joint and conduction with the imbedding port. The placement opening coincides locally with the lower part.
The tops of the front side and the rear side of the supporting seat 1 are provided with bulges extending outwards, the tops of the bulges are flush with the top of the supporting seat 1, and gaps between adjacent bulges are opposite to openings of adjacent centrifuge tube placing holes; the protrusion distance of the front side of the supporting seat 1 is different from the protrusion distance of the rear side of the supporting seat 1. The positioning structure is convenient for sliding into the equipment as a magnetic rack through the bulge. The distance between adjacent bulges is used for knowing whether the magnetic force frame slides into the large hole side or the small hole side, so that the positioning of the front side and the rear side of the magnetic force frame is facilitated.
The support seat 1 comprises an upper part, a middle part and a lower part which are arranged from top to bottom; the lower part is provided with a front extension 7 and a rear extension 8; the front side and the rear side of the middle part are both retracted at the upper part and the lower part; the central angle of the centrifuge tube placing hole at the upper part is larger than the central angle of the centrifuge tube placing hole at the middle part. The upper part is provided with a bulge. Further improve the stability of putting in centrifuging tube place the hole. The upper, middle and lower left sides are flush, and the right sides are also flush.
Specific example 2, based on specific example 1, the centrifuge tube placement holes on the front and rear sides of the support seat are different in number; and the left and right mirror symmetry setting of the centrifuge tube placing holes of one side with less centrifuge tube placing holes is arranged on the supporting seat, and the center of the left and right direction of the one side with less centrifuge tube placing holes is provided with a positioning bulge. The positioning of the central position of the magnetic rack in the left-right direction is convenient. The number of centrifuge tube placing holes on any one side of the front side and the rear side of the supporting seat is twice as many as the number of centrifuge tube placing holes on the other side.
Example 3 the magnet of example 1 was a N52 strength neodymium-iron-boron permanent magnet. The magnetic field intensity is high, the magnetic beads can be gathered efficiently, and the separation of nucleic acid and waste liquid is facilitated. Meanwhile, heat generated by electrifying the electromagnet in the extraction process is avoided, and the damage to biological materials is less.
The material of the supporting seat is aviation aluminum alloy. The aviation aluminum alloy material reduces the occupied volume under the condition of keeping the strength of the frame body as much as possible.
The foregoing is merely a preferred embodiment of the present utility model and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present utility model, which are intended to be comprehended within the scope of the present utility model.
Claims (10)
1. The multipurpose magnetic rack comprises a magnetic rack substrate, wherein the magnetic rack substrate comprises a supporting seat, and is characterized in that two rows of centrifuge tube placing holes which are arranged front and back are formed in the supporting seat, an opening is formed in one side of the centrifuge tube placing holes in the radial direction, and the opening is positioned on the side wall of the supporting seat;
the inner diameter of the centrifuge tube placing hole at the front side is different from that of the centrifuge tube placing hole at the rear side;
each centrifuge tube placing hole is in butt joint and conduction with a mounting groove for placing a magnet, and the magnet is arranged in the mounting groove;
the bottom of the supporting seat is provided with a front extending part extending forwards and a rear extending part extending backwards, and a limiting groove with an opening at the lower end is formed between the front extending part and the rear extending part.
2. A multipurpose magnetic stand as claimed in claim 1, wherein: the opening end of the mounting groove is in butt joint and conduction with an imbedding port for mounting a magnet, and one side of the imbedding port, which is far away from the mounting groove, is positioned on the side wall of the supporting seat;
the opening is in butt joint and conduction with the imbedding opening.
3. A multipurpose magnetic stand as claimed in claim 1, wherein: the magnet is connected with the mounting groove in an interference fit mode.
4. A multipurpose magnetic stand as claimed in claim 1, wherein: the central angle of the centrifuge tube placing hole is larger than 270 degrees and smaller than 360 degrees.
5. A multipurpose magnetic stand as claimed in claim 1, wherein: the tops of the front side and the rear side of the supporting seat are provided with bulges extending outwards, the tops of the bulges are flush with the top of the supporting seat, and gaps between adjacent bulges are opposite to openings of adjacent centrifuge tube placing holes;
the protrusion distance of the front side of the supporting seat is different from the protrusion distance of the rear side of the supporting seat.
6. A multipurpose magnetic stand as claimed in claim 1, wherein: the supporting seat comprises an upper part, a middle part and a lower part which are arranged from top to bottom;
the lower portion is provided with the front extension and the rear extension;
the front side and the rear side of the middle part are both inwards contracted at the upper part and the lower part;
the central angle of the centrifuge tube placing hole positioned at the upper part is larger than the central angle of the centrifuge tube placing hole positioned at the middle part.
7. A multipurpose magnetic stand as claimed in claim 1, wherein: the number of centrifuge tube placing holes on any one side of the front side and the rear side of the supporting seat is twice as many as the number of centrifuge tube placing holes on the other side.
8. A multipurpose magnetic stand as claimed in claim 1, wherein: the number of centrifuge tube placing holes on the front side and the rear side of the supporting seat is different;
and the centrifuge tube placing holes on one side with less centrifuge tube placing holes are arranged in a left-right mirror symmetry manner on the supporting seat, and the center of the left-right direction on one side with less centrifuge tube placing holes is provided with a positioning bulge on the supporting seat.
9. A multipurpose magnetic shelf as claimed in any one of claims 1 to 8, wherein: the magnet is an N52-strength neodymium-iron-boron permanent magnet.
10. A multipurpose magnetic shelf as claimed in any one of claims 1 to 8, wherein: the material of supporting seat is aviation aluminum alloy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320783747.3U CN219930025U (en) | 2023-04-11 | 2023-04-11 | Multipurpose magnetic rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320783747.3U CN219930025U (en) | 2023-04-11 | 2023-04-11 | Multipurpose magnetic rack |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219930025U true CN219930025U (en) | 2023-10-31 |
Family
ID=88489794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320783747.3U Active CN219930025U (en) | 2023-04-11 | 2023-04-11 | Multipurpose magnetic rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219930025U (en) |
-
2023
- 2023-04-11 CN CN202320783747.3U patent/CN219930025U/en active Active
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