CN212770659U

CN212770659U - 48 hole bar magnet cover

Info

Publication number: CN212770659U
Application number: CN202021190884.9U
Authority: CN
Inventors: 覃莉清; 张雅雯
Original assignee: Suzhou Kangmengyuan Biotechnology Co ltd
Current assignee: Suzhou Kangmengyuan Biotechnology Co ltd
Priority date: 2020-06-23
Filing date: 2020-06-23
Publication date: 2021-03-23
Anticipated expiration: 2030-06-23

Abstract

The utility model relates to a 48-hole magnetic bar sleeve, which comprises a base plate; 48 pipe sleeves which are uniformly distributed in six rows and eight columns are vertically arranged on the substrate; one end of each of the 48 pipe sleeves connected with the base plate is open, the other end of each pipe sleeve is closed, and a magnetic rod can be accommodated in each pipe sleeve; the utility model discloses can form a complete set and be used for 48 hole's deep hole board to carry out the magnetic separation operation, and compare with the bar magnet cover of current 96 holes or 384 holes, clearance grow between the pipe box, the magnetic bead adsorbs in the bar magnet cover surface at the removal in-process, and the favourable sample cross infection that reduces to improve the degree of accuracy.

Description

48 hole bar magnet cover

Technical Field

The utility model relates to the field of biology, in particular to a 48-hole magnetic rod sleeve.

Background

With the rapid development of the medical field, more and more nucleic acid-based biological experiments are emerging, and the extraction and detection of nucleic acids can help to make rapid diagnosis of the disease of patients. The magnetic bead method is a novel nucleic acid extraction technology with nano biological magnetic beads as carriers, nucleic acid molecules can be specifically identified and combined with silicon hydroxyl on the surfaces of the magnetic beads, and are aggregated or dispersed under the action of an external magnetic field, so that the nucleic acid is separated and purified.

The existing magnetic separation technology has two modes, one is to place a deep hole plate filled with a liquid sample on a magnetic frame, and the other is to insert a magnetic rod sleeve provided with a magnetic rod into the deep hole plate filled with the liquid sample; for example, in the deep hole plate disclosed in the prior art 201620175899.5, the number of the cylindrical deep holes is 48, and a non-common-wall structure is adopted, so that compared with a wall-connected structure in the prior art, the contact area between the holes is reduced, the edge distance between the holes is increased, and when liquid transfer, oscillation and other operations are performed, the liquid transfer phenomenon of liquid is favorably reduced, and the cross contamination of samples is further reduced; however, the common magnetic rod sleeve at present only has 96 holes or 384 holes, and does not have a 48-hole magnetic rod sleeve.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a 48 hole bar covers in order to overcome prior art not enough.

In order to achieve the above purpose, the utility model adopts the technical scheme that: a48-hole magnetic rod sleeve comprises a substrate; 48 pipe sleeves which are uniformly distributed in six rows and eight columns are vertically arranged on the substrate; and 48 pipe sleeves are opened at one end connected with the base plate, the other end is closed, and the magnetic rods can be accommodated in the pipe sleeves.

Preferably, the closed end of the pipe sleeve is of a hemispherical structure.

Preferably, the sleeve is tapered with an open end diameter greater than a closed end diameter.

Preferably, four corners of the substrate are respectively provided with a bayonet protruding the upper surface of the substrate.

Preferably, the base plate, the pipe sleeve and the bayonet are integrally formed by injection molding.

Preferably, a reinforcing part is further arranged at the joint of the opening end of the pipe sleeve and the base plate; the wall thickness of the reinforcement is greater than the wall thickness of the pipe sleeve.

Preferably, the side wall of the reinforcing part is arc-shaped, and the diameter of the upper end is larger than that of the lower end.

Preferably, the base plate is provided with a through hole for mounting the pipe sleeve; the hole wall of the through hole is of an inwards concave structure; and the outer surface of the reinforcing part is provided with a convex structure corresponding to the concave structure.

Preferably, the concave structure and the convex structure are both arc-shaped.

Preferably, the upper end of the reinforcing part is provided with a positioning flange; the diameter of the positioning flange is larger than that of the through hole.

Because of above-mentioned technical scheme's application, compared with the prior art, the utility model have the following advantage:

the utility model discloses can form a complete set and be used for 48 hole's deep hole board to carry out the magnetic separation operation, and compare with the bar magnet cover of current 96 holes or 384 holes, clearance grow between the pipe box, the magnetic bead adsorbs in the bar magnet cover surface at the removal in-process, and the favourable sample cross infection that reduces to improve the degree of accuracy.

Drawings

The technical scheme of the utility model is further explained by combining the attached drawings as follows:

fig. 1 is a schematic structural view of a 48-hole magnetic rod sleeve according to the present invention;

fig. 2 is a sectional view of a 48-hole magnetic rod sleeve according to the present invention;

fig. 3 is a schematic view of the installation of the base plate and the single pipe sleeve according to the present invention.

Wherein: 1. a substrate; 2. pipe sleeve; 3. a bayonet; 4. a reinforcing portion; 5. a convex structure; 6. and positioning the flanges.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

Fig. 1-2 show a 48-hole magnetic rod sleeve according to the present invention, which comprises a substrate 1; the substrate 1 is vertically provided with 48 pipe sleeves 2 which are uniformly distributed in six rows and eight columns; one end of each of the 48 pipe sleeves 2 connected with the substrate 1 is open, the other end of each pipe sleeve is closed, and a magnetic rod can be accommodated in each pipe sleeve; 48 hole bar cover can form a complete set and be used for 48 hole deep hole boards to carry out the magnetic separation operation, and compare with current 96 hole or 384 hole bar covers, the clearance grow between the pipe box 2, the magnetic bead adsorbs at bar cover surface in the removal in-process, favourable reduction sample cross infection to improve the degree of accuracy.

Further, the blind end of pipe box 2 is half spherical structure, compares with the blind end of V-arrangement structure, and not only absorbent magnetic bead is more even, and can avoid appearing the hanging phenomenon, and simultaneously, the distance of bar magnet distance blind end bottom among the half spherical structure is littleer than the distance of bar magnet distance blind end bottom among the V-arrangement structure, and then reaches better magnetism and inhale the effect.

Furthermore, the pipe sleeve 2 is conical, and the diameter of the opening end of the pipe sleeve is larger than that of the closing end of the pipe sleeve, so that the pipe sleeve can be conveniently inserted into a deep hole plate.

Further, four corners of the substrate 1 are respectively provided with bayonets 3 protruding the upper surface of the substrate 1, so that the substrate can be applied to nucleic acid extraction equipment, and is convenient for mechanical arm grabbing.

Further, base plate 1, pipe box 2, the integrative injection moulding of bayonet socket 3, not only the manufacturing of being convenient for, and can guarantee that the blind end of pipe box 2 is located same horizontal plane, the error that significantly reduces.

Furthermore, a reinforcing part 4 is arranged at the joint of the opening end of the pipe sleeve 2 and the base plate 1; the wall thickness of the reinforcing part 4 is larger than that of the pipe sleeve 2, so that the reinforcing effect is achieved, and the connecting strength of the pipe sleeve 2 is improved.

Further, the side wall of the reinforcing part 4 is arc-shaped, and the diameter of the upper end is larger than that of the lower end; not only plays a transition role, but also plays a buffering effect.

Example two:

as shown in fig. 3, the difference from the first embodiment is that: the base plate 1 and the pipe sleeve 2 are in detachable design; the base plate 1 is provided with a through hole for mounting the pipe sleeve 2; the hole wall of the through hole is of an inwards concave structure; the outer surface of the reinforcing part 4 is provided with a convex structure 5 corresponding to the concave structure; the pipe sleeve 2 can be clamped on the base plate 1 through the matching of the concave structure and the convex structure 5, so that the damaged single sleeve pipe can be conveniently replaced, and the waste phenomenon caused by the fact that the whole magnetic rod sleeve needs to be replaced due to the damage of the single sleeve pipe is avoided; of course, the base plate 1 and the reinforcing part 4 may be screwed together.

Further, the concave structure and the convex structure 5 are both arc-shaped, so that the installation and the disassembly are convenient.

Further, a positioning flange 6 is arranged at the upper end of the reinforcing part 4; the diameter of the positioning flange 6 is larger than that of the through hole, so that the positioning function is achieved.

The above is only a specific application example of the present invention, and does not constitute any limitation to the protection scope of the present invention. All the technical solutions formed by equivalent transformation or equivalent replacement fall within the protection scope of the present invention.

Claims

1. A48 hole bar cover which is characterized in that: comprises a substrate; 48 pipe sleeves which are uniformly distributed in six rows and eight columns are vertically arranged on the substrate; and 48 pipe sleeves are opened at one end connected with the base plate, the other end is closed, and the magnetic rods can be accommodated in the pipe sleeves.

2. The 48-hole magnetic sleeve as claimed in claim 1, wherein: the closed end of the pipe sleeve is of a hemispherical structure.

3. The 48-hole magnetic sleeve according to claim 1 or 2, characterized in that: the pipe sleeve is conical, and the diameter of the opening end of the pipe sleeve is larger than that of the closed end of the pipe sleeve.

4. A 48-hole magnet rod sleeve as claimed in claim 3, wherein: the four corners of the substrate are respectively provided with bayonets protruding out of the upper surface of the substrate.

5. The 48-hole magnetic sleeve according to claim 4, wherein: the base plate, the pipe sleeve and the bayonet are integrally formed in an injection molding mode.

6. The 48-hole magnetic sleeve according to claim 5, wherein: a reinforcing part is also arranged at the joint of the opening end of the pipe sleeve and the substrate; the wall thickness of the reinforcement is greater than the wall thickness of the pipe sleeve.

7. The 48-hole magnetic sleeve according to claim 6, wherein: the lateral wall of rib is the arc, and the upper end diameter is greater than the lower extreme diameter.

8. The 48-hole magnetic sleeve according to claim 7, wherein: the base plate is provided with a through hole for mounting the pipe sleeve; the hole wall of the through hole is of an inwards concave structure; and the outer surface of the reinforcing part is provided with a convex structure corresponding to the concave structure.

9. The 48-hole magnetic rod sleeve according to claim 8, wherein: the concave structure and the convex structure are both arc-shaped.

10. The 48-hole magnetic sleeve according to claim 9, wherein: the upper end of the reinforcing part is provided with a positioning flange; the diameter of the positioning flange is larger than that of the through hole.