CN114032171A - Multifunctional magnetic rod sleeve - Google Patents
Multifunctional magnetic rod sleeve Download PDFInfo
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- CN114032171A CN114032171A CN202111366561.XA CN202111366561A CN114032171A CN 114032171 A CN114032171 A CN 114032171A CN 202111366561 A CN202111366561 A CN 202111366561A CN 114032171 A CN114032171 A CN 114032171A
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- magnetic rod
- rod sleeve
- bar magnet
- magnet cover
- groove
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
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Abstract
The invention provides a multifunctional magnetic rod sleeve, which belongs to the technical field of nucleic acid extraction and comprises a magnetic rod sleeve; the fixing plate is arranged at the side end of the magnetic rod sleeve, a rectangular groove is formed in the upper end of the fixing plate, and a clamping groove is formed in the side end of the rectangular groove; and latch mechanism, latch mechanism includes the fixture block, the circular recess, a spring, the lug, the fixture block sets up in the circumference surface of bar magnet cover, the side of fixture block is seted up in the circular recess, spring fixed connection is in the circular recess, lug fixed connection is in the side of spring, lug and draw-in groove activity joint, thereby it fixes better between bar magnet cover and the fixed plate to make the bar magnet cover when carrying out the use through the latch mechanism that is provided with, and the bar magnet cover can arrange and make up better, thereby further promotion bar magnet cover's multifunctionality.
Description
Technical Field
The invention belongs to the technical field of nucleic acid extraction, and particularly relates to a multifunctional magnetic rod sleeve.
Background
With the rapid development of the medical field, more and more nucleic acid-based biological experiments are emerging, and the extraction and detection of nucleic acids can help to make rapid diagnosis of the disease of patients. The magnetic bead method is a novel nucleic acid extraction technology with nano biological magnetic beads as carriers, nucleic acid molecules can be specifically identified and combined with silicon hydroxyl on the surfaces of the magnetic beads, and are aggregated or dispersed under the action of an external magnetic field, so that the nucleic acid is separated and purified. At present, the magnetic bead method for extracting nucleic acid generally comprises four main steps of cracking, combining, washing and eluting. After a sample is cracked, adding a binding solution to bind magnetic beads and nucleic acid, sleeving a magnetic rod in a magnetic rod sleeve, inserting the magnetic rod into the cracking solution, adsorbing the magnetic beads on the surface of the magnetic rod sleeve under the action of a magnetic field, transferring the magnetic beads into a washing solution by the magnetic rod-magnetic rod sleeve, and washing for 2 times generally; after washing, the magnetic rod-magnetic rod sleeve transfers the magnetic beads into the eluent to elute the nucleic acids attached to the magnetic beads. The eluate with the nucleic acids is then transferred to a PCR reaction tube for subsequent molecular diagnostic testing, such as PCR testing.
The magnetic rod sleeve in the prior art is often single in functionality and cannot be used in a multifunctional mode better when being used, so that the application range of the magnetic rod sleeve is small, and the service cycle of the magnetic rod sleeve is short.
Disclosure of Invention
The invention aims to provide a multifunctional magnetic rod sleeve, and aims to solve the problems that the prior art is single in functionality and cannot be used in a multifunctional mode.
In order to achieve the purpose, the invention provides the following technical scheme:
a multi-functional magnetic rod cover comprising:
a magnetic rod sleeve;
the fixing plate is arranged at the side end of the magnetic rod sleeve, a rectangular groove is formed in the upper end of the fixing plate, and a clamping groove is formed in the side end of the rectangular groove; and
the clamping mechanism comprises a clamping block, a circular groove, a spring and a convex block, the clamping block is arranged on the circumferential surface of the magnetic rod sleeve, the circular groove is formed in the side end of the clamping block, the spring is fixedly connected into the circular groove, the convex block is fixedly connected to the side end of the spring, and the convex block is movably clamped with the clamping groove.
As a preferable scheme of the invention, the circumferential surface of the magnetic rod sleeve is fixedly connected with a reinforcing rib; the wall thickness of the reinforcing rib is larger than that of the magnetic rod sleeve.
As a preferable scheme of the invention, the reinforcing rib is movably clamped with a connecting frame, one side end of the connecting frame is provided with a trapezoidal groove, and the trapezoidal groove is matched with the reinforcing rib.
In a preferred embodiment of the present invention, the circumferential surface of the magnet rod sleeve is provided with scale marks.
As a preferable scheme of the invention, a sealing cap is fixedly connected to the upper end of the connecting frame, and the sealing cap is matched with an upper end opening of the magnetic rod sleeve.
In a preferred embodiment of the present invention, the height of the magnetic rod sleeve is mm ±. mm.
In a preferred embodiment of the present invention, the magnetic rod sleeve is conical, and the diameter of the open end of the magnetic rod sleeve is larger than that of the closed end of the magnetic rod sleeve.
In a preferred embodiment of the present invention, the closed end of the magnetic rod sleeve has a hemispherical structure.
Compared with the prior art, the invention has the beneficial effects that:
1. in this scheme, thereby make the bar magnet cover fix between bar magnet cover and the fixed plate better when carrying out the use through the latch mechanism that is provided with, thereby make the bar magnet cover arrange better and make up, thereby further promotion bar magnet cover's functional, and the multifunctionality of bar magnet cover, thereby and the scale mark that the circumference surface through the bar magnet cover was provided with makes the bar magnet cover read through the milliliter of the inside solution of scale mark better when carrying out the use.
2. In this scheme, set up some rectangular channels through the upper end of fixed plate and can make the bar magnet cover can fix through between latch mechanism and the fixed plate better, and the clearance of rectangular channel is bigger than current relatively to make the bar magnet cover can avoid infecting better when testing and examining, thereby lifting means's detection precision, the practicality of reinforcing equipment, lifting means's functionality.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a first perspective view of the present invention;
FIG. 2 is a second perspective view of the present invention;
FIG. 3 is a first exploded view of the present invention;
FIG. 4 is a second exploded view of the present invention;
FIG. 5 is an enlarged view of a portion of the invention at A in FIG. 4;
fig. 6 is a third exploded view of the present invention.
In the figure: 1. a fixing plate; 2. a rectangular groove; 3. a card slot; 4. a clamping block; 5. a magnetic rod sleeve; 6. scale lines; 7. reinforcing ribs; 8. a connecting frame; 9. a trapezoidal groove; 10. a sealing cap; 11. a circular groove; 12. a spring; 13. and (4) a bump.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1
Referring to fig. 1-6, the present invention provides the following technical solutions:
a multi-functional magnetic rod cover comprising:
a magnetic rod sleeve 5;
the fixing plate 1 is arranged at the side end of the magnetic rod sleeve 5, the upper end of the fixing plate 1 is provided with a rectangular groove 2, and the side end of the rectangular groove 2 is provided with a clamping groove 3; and
the clamping mechanism comprises a clamping block 4, a circular groove 11, a spring 12 and a convex block 13, the clamping block 4 is arranged on the circumferential surface of the magnetic rod sleeve 5, the circular groove 11 is arranged at the side end of the clamping block 4, the spring 12 is fixedly connected in the circular groove 11, the convex block 13 is fixedly connected at the side end of the spring 12, and the convex block 13 is movably clamped with the clamping groove 3.
In the embodiment of the invention, the magnetic rod sleeve 5 is made of transparent glass material, so that the magnetic rod sleeve 5 can better display the internal solution when in use, thereby improving the practicability of the equipment and the functionality of the equipment, the fixed plate 1 is made of recyclable plastic material, so that the fixed plate 1 can be better recycled after in use, thereby further improving the environmental protection function of the equipment, the rectangular grooves 2 play a role in placing the fixture blocks 4, the magnetic rod sleeve 5 can be better fixed with the fixed plate 1 through the clamping mechanism by the rectangular grooves 2 arranged at the upper end of the fixed plate 1, and the gap of the rectangular grooves 2 is larger than that of the prior art, so that the magnetic rod sleeve 5 can better avoid infection when in test and detection, thereby improving the detection accuracy of the equipment, the practicality of reinforcing equipment, lifting means's functionality, thereby make bar magnet cover 5 fix between bar magnet cover 5 and fixed plate 1 better when using through the latch mechanism that is provided with, thereby make bar magnet cover 5 arrange and make up better, thereby further promotion bar magnet cover 5's functionality, and bar magnet cover 5's multifunctionality, thereby and the scale mark 6 that is provided with through the circumferential surface of bar magnet cover 5 makes bar magnet cover 5 read through the milliliter of the inside solution of scale mark 6 better when using, wherein fixture block 4 plays and carries out connection effect with bar magnet cover 5, circular slot 11 plays and realizes carrying out fixed action with spring 12, spring 12 plays and realizes connecting lug 13, thereby make lug 13 can be better and draw-in groove 3 between carry out movable joint effect.
Specifically, referring to the figure, the circumferential surface of the magnetic rod sleeve 5 is fixedly connected with a reinforcing rib 7; the wall thickness of the reinforcing ribs 7 is larger than that of the magnetic rod sleeve 5.
In this embodiment: thereby make the further promotion of the stability of bar magnet cover 5 through the fixed strengthening rib 7 in the circumference surface of bar magnet cover 5, and the wall thickness of strengthening rib 7 is great than the wall thickness of bar magnet cover 5 for bar magnet cover 5 can further promotion life.
Specifically referring to fig. 4 and 5, the reinforcing rib 7 is movably clamped with a connecting frame 8, one side end of the connecting frame 8 is provided with a trapezoidal groove 9, and the trapezoidal groove 9 is matched with the reinforcing rib 7.
In this embodiment: the link 8 plays and to carry out the fixed action better with sealed cap 10, thereby make through some sealed caps 10 of the upper end fixed connection of link 8 can be better after buckling with the upper end opening of bar magnet cover 5 sealed, thereby make bar magnet cover 5 can further reinforcing bar magnet cover 5's sealed function when using, trapezoidal groove 9 plays the realization can carry out the joint better between link 8 and the strengthening rib 7, thereby make link 8 can dismantle better, thereby strengthen the functionality of link 8.
Specifically referring to fig. 6, the circumference surface of the magnetic rod sleeve 5 is provided with scale marks 6.
In this embodiment: thereby make the staff can carry out the milliliter of the inside solution of bar magnet cover 5 better and read through scale mark 6 that the circumference part at bar magnet cover 5 was provided with to make the practicality and the functionality of bar magnet cover 5 further promote.
Specifically referring to fig. 5 and 6, the upper end of the connecting frame 8 is fixedly connected with a sealing cap 10, and the sealing cap 10 is matched with the upper end opening of the magnetic rod sleeve 5.
In this embodiment: after the upper end opening of sealed cap 10 and bar magnet cover 5 meshes, bar magnet cover 5 when removing or transmitting the use this moment, can further strengthen the sealed function of equipment to further promote the precision of bar magnet cover 5, strengthen the practicality of equipment.
Specifically, referring to fig. 6, the height of the magnetic rod sleeve 5 is 23mm ± 0.02 mm.
In this embodiment: the height of the magnetic rod sleeve 5 is 23mm +/-0.02 mm, so that the magnetic rod sleeve 5 can better enhance the test function when in use, and further the practicability of the equipment is further enhanced.
Specifically, referring to fig. 1 and 3, the magnetic rod sleeve 5 is tapered, and the diameter of the open end is larger than that of the closed end.
In this embodiment: thereby the shape through bar magnet cover 5 is the toper and makes solution guarantee better after placing in bar magnet cover 5 that bar magnet cover 5 can strengthen its stability better when using, is greater than the blind end diameter through its open end diameter to make it can empty the solution of inside better after the test is accomplished, thereby further promote the practicality.
Specifically, referring to fig. 2, the closed end of the magnetic rod sleeve 5 is a hemispherical structure.
In this embodiment: the blind end through bar magnet cover 5 is the hemisphere structure to make bar magnet cover 5 using can make bar magnet cover 5's structure can be more stable, thereby make the life of equipment can promote better.
The working principle and the using process of the invention are as follows: at first locate the circumference surface of bar cover 5 with 4 covers of fixture block, then place fixture block 4 and work in rectangular channel 2 this moment latch mechanism, lug 13 at this moment when lug 13 is close to the draw-in groove 3 that has been seted up to the side of rectangular channel 2 this moment lug 13 at first stretches out and draws back through spring 12, then slide lug 13 area, rectangular channel 2 and fixture block 4 phase-match this moment, then lug 13 is gone into in draw-in groove 3 this moment lug 13 and draw-in groove 3 and is matchd, accomplish the joint function of equipment this moment, thereby it can be better fixed between bar cover 5 and fixed plate 1 to make bar cover 5 arrange better and make up when using, thereby make bar cover 5 can arrange better and make up, thereby further promotion bar cover 5's functionality, and bar cover 5's multifunctionality, and thereby it carries out bar cover 5 better through scale mark 6 that bar cover 5's circumferential surface is provided with thereby make bar cover 5 carry out bar cover 5 through scale mark 6 when using better The internal solution is read in milliliters.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. A multi-functional magnetic rod cover, comprising:
a magnetic rod sleeve (5);
the fixing plate (1) is arranged at the side end of the magnetic rod sleeve (5), a rectangular groove (2) is formed in the upper end of the fixing plate (1), and a clamping groove (3) is formed in the side end of the rectangular groove (2); and
clamping mechanism, clamping mechanism includes fixture block (4), circular recess (11), spring (12), lug (13), fixture block (4) set up in the circumference surface of bar magnet cover (5), the side of fixture block (4) is seted up in circular recess (11), spring (12) fixed connection is in circular recess (11), lug (13) fixed connection is in the side of spring (12), lug (13) and draw-in groove (3) activity joint.
2. The multifunctional magnetic rod sleeve as claimed in claim 1, wherein: the circumferential surface of the magnetic rod sleeve (5) is fixedly connected with a reinforcing rib (7); the wall thickness of the reinforcing rib (7) is larger than that of the magnetic rod sleeve (5).
3. The multifunctional magnetic rod sleeve as claimed in claim 2, wherein: the reinforcing rib (7) is movably clamped with a connecting frame (8), a trapezoidal groove (9) is formed in one side end of the connecting frame (8), and the trapezoidal groove (9) is matched with the reinforcing rib (7).
4. The multifunctional magnetic rod sleeve as claimed in claim 3, wherein: the circumference surface of the magnetic rod sleeve (5) is provided with scale marks (6).
5. The multifunctional magnetic rod sleeve as claimed in claim 4, wherein: the upper end of the connecting frame (8) is fixedly connected with a sealing cap (10), and the sealing cap (10) is matched with an upper end opening of the magnetic rod sleeve (5).
6. The multifunctional magnetic rod sleeve as claimed in claim 5, wherein: the height of the magnetic rod sleeve (5) is 23mm +/-0.02 mm.
7. The multifunctional magnetic rod sleeve as claimed in claim 5, wherein: the magnetic rod sleeve (5) is conical, and the diameter of the opening end of the magnetic rod sleeve is larger than that of the closed end of the magnetic rod sleeve.
8. The multifunctional magnetic rod sleeve as claimed in claim 6, wherein: the closed end of the magnetic rod sleeve (5) is of a hemispherical structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111366561.XA CN114032171A (en) | 2021-11-18 | 2021-11-18 | Multifunctional magnetic rod sleeve |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111366561.XA CN114032171A (en) | 2021-11-18 | 2021-11-18 | Multifunctional magnetic rod sleeve |
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| Publication Number | Publication Date |
|---|---|
| CN114032171A true CN114032171A (en) | 2022-02-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111366561.XA Pending CN114032171A (en) | 2021-11-18 | 2021-11-18 | Multifunctional magnetic rod sleeve |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017152698A1 (en) * | 2016-03-08 | 2017-09-14 | 湖南圣湘生物科技有限公司 | Magnetic bead-based nucleic acid extraction apparatus and use method |
| CN210215361U (en) * | 2019-06-12 | 2020-03-31 | 杭州丰盈生物科技有限公司 | Special eight-linkage magnetic rod sleeve for nucleic acid extraction |
| CN212640511U (en) * | 2020-06-23 | 2021-03-02 | 苏州康梦元生物科技有限公司 | Single-row magnetic rod sleeve |
| CN212770659U (en) * | 2020-06-23 | 2021-03-23 | 苏州康梦元生物科技有限公司 | 48 hole bar magnet cover |
| CN214529057U (en) * | 2021-01-19 | 2021-10-29 | 武汉纳磁生物科技有限公司 | Self-locking magnetic rod sleeve assembly |
| CN214529058U (en) * | 2021-02-05 | 2021-10-29 | 厦门甄准生物技术有限公司 | Nucleic acid extraction magnetic rod sleeve and extraction device |
-
2021
- 2021-11-18 CN CN202111366561.XA patent/CN114032171A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017152698A1 (en) * | 2016-03-08 | 2017-09-14 | 湖南圣湘生物科技有限公司 | Magnetic bead-based nucleic acid extraction apparatus and use method |
| CN210215361U (en) * | 2019-06-12 | 2020-03-31 | 杭州丰盈生物科技有限公司 | Special eight-linkage magnetic rod sleeve for nucleic acid extraction |
| CN212640511U (en) * | 2020-06-23 | 2021-03-02 | 苏州康梦元生物科技有限公司 | Single-row magnetic rod sleeve |
| CN212770659U (en) * | 2020-06-23 | 2021-03-23 | 苏州康梦元生物科技有限公司 | 48 hole bar magnet cover |
| CN214529057U (en) * | 2021-01-19 | 2021-10-29 | 武汉纳磁生物科技有限公司 | Self-locking magnetic rod sleeve assembly |
| CN214529058U (en) * | 2021-02-05 | 2021-10-29 | 厦门甄准生物技术有限公司 | Nucleic acid extraction magnetic rod sleeve and extraction device |
Non-Patent Citations (1)
| Title |
|---|
| 张开慧;: "新一代的磁珠法核酸自动提取仪研究进展", 甘肃畜牧兽医, vol. 49, no. 04, pages 53 - 56 * |
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