CN114231385A - Magnetic rod sleeve with high practicability - Google Patents

Magnetic rod sleeve with high practicability Download PDF

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Publication number
CN114231385A
CN114231385A CN202111366890.4A CN202111366890A CN114231385A CN 114231385 A CN114231385 A CN 114231385A CN 202111366890 A CN202111366890 A CN 202111366890A CN 114231385 A CN114231385 A CN 114231385A
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CN
China
Prior art keywords
spliced pole
rod sleeve
connecting plate
plate
trapezoidal
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Pending
Application number
CN202111366890.4A
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Chinese (zh)
Inventor
袁义勇
刘子贤
刘刚
刘子德
赵华
唐波
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Meidong Huicheng Life Technology Kunshan Co ltd
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Meidong Huicheng Life Technology Kunshan Co ltd
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Priority to CN202111366890.4A priority Critical patent/CN114231385A/en
Publication of CN114231385A publication Critical patent/CN114231385A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
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  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)

Abstract

The invention provides a magnetic rod sleeve with high practicability, which belongs to the technical field of nucleic acid extraction and comprises a connecting plate; the upper end of the connecting plate is provided with a slot, and the side end of the connecting plate is provided with a first circular groove; and latch mechanism, latch mechanism includes first trapezoidal plate, the second spliced pole, first spliced pole, V type groove, hollow section of thick bamboo and V type fixture block, first trapezoidal plate and the equal sliding connection of second spliced pole are in the rectangular channel, second spliced pole fixed connection is in the side of second trapezoidal plate, first spliced pole fixed connection is in the side of first trapezoidal plate, thereby it can carry out mutual joint to make latch mechanism through the latch mechanism that is provided with, thereby it is fixed to make the connecting plate carry out the joint with another group, and then further make the bar cover can make up better with the fixed of connecting plate, thereby make equipment can strengthen the combined function and the dismantlement function of connecting plate better.

Description

Magnetic rod sleeve with high practicability
Technical Field
The invention belongs to the technical field of nucleic acid extraction, and particularly relates to a magnetic rod sleeve with high practicability.
Background
With the rapid development of the medical field, more and more nucleic acid-based biological experiments are emerging, and the extraction and detection of nucleic acids can help to make rapid diagnosis of the disease of patients. The magnetic bead method nucleic acid extraction is a novel nucleic acid extraction technology taking nano biological magnetic beads as carriers, nucleic acid molecules can be specifically identified and combined with silicon hydroxyl on the surfaces of the magnetic beads, and are aggregated or dispersed under the action of an external magnetic field, so that nucleic acid separation and purification are carried out, and the conventional magnetic bead method nucleic acid extraction generally comprises four main steps of cracking, combining, washing and eluting. After a sample is cracked, adding a binding solution to bind magnetic beads and nucleic acid, sleeving a magnetic rod in a magnetic rod sleeve, inserting the magnetic rod into the cracking solution, adsorbing the magnetic beads on the surface of the magnetic rod sleeve under the action of a magnetic field, transferring the magnetic beads into a washing solution by the magnetic rod-magnetic rod sleeve, and washing for 2 times generally; after washing, the magnetic rod-magnetic rod sleeve transfers the magnetic beads into the eluent to elute the nucleic acids attached to the magnetic beads. The eluate with the nucleic acids is then transferred to a PCR reaction tube for subsequent molecular diagnostic testing, such as PCR testing.
In the prior art, the magnetic rod sleeve is inconvenient to fix when in use and the practicability of the equipment is affected because the combination and disassembly of a plurality of groups cannot be carried out after the magnetic rod sleeve is fixed.
Disclosure of Invention
The invention aims to provide a magnetic rod sleeve with high practicability, and aims to solve the problems that the fixing is inconvenient and the multi-group combination and disassembly cannot be carried out in the prior art.
In order to achieve the purpose, the invention provides the following technical scheme:
a high utility magnet sleeve comprising:
a connecting plate;
a rectangular groove; the upper end of the connecting plate is provided with a rectangular groove, the upper end of the connecting plate is provided with a slot, and the side end of the connecting plate is provided with a first circular groove; and
clamping mechanism, clamping mechanism includes first trapezoidal plate, second spliced pole, first spliced pole, V type groove, hollow section of thick bamboo and V type fixture block, the equal sliding connection of first trapezoidal plate and second spliced pole is in the rectangular channel, second spliced pole fixed connection is in the side of second trapezoidal plate, first spliced pole fixed connection is in the side of first trapezoidal plate, the side of second spliced pole is seted up in V type groove, hollow section of thick bamboo fixed connection is in the side of first spliced pole, V type fixture block fixed connection is in hollow section of thick bamboo.
As a preferable scheme of the invention, a third circular groove is formed at a side end of the rectangular groove, a trapezoidal button is slidably connected to an end of the first trapezoidal plate close to the end of the second trapezoidal plate, an arc-shaped groove is formed at a side end of the trapezoidal button, a limiting rod is arranged in the arc-shaped groove, and a side end of the limiting rod is fixedly connected to the inside of the third circular groove.
As a preferable scheme of the present invention, a first spring is sleeved on a circumferential surface of the second connecting column, and one side end of the first spring is connected to one side end of the rectangular groove.
As a preferable aspect of the present invention, a second spring is sleeved on a circumferential surface of the first connecting post, and one side end of the second spring is connected to the other side end of the rectangular groove.
As a preferred scheme of the present invention, a magnetic rod sleeve is movably clamped in the slot, and a reinforcing rib is fixedly connected to the circumferential surface of the magnetic rod sleeve.
As a preferable scheme of the invention, a second circular groove is formed at a side end of the connecting plate, a concave clamping plate is fixedly connected inside the second circular groove, and an E-shaped clamping block is movably clamped at a side end of the second circular groove.
As a preferable scheme of the invention, the concave clamping plate and the E-shaped clamping block can be replaced, and the surfaces of the connecting plates are both subjected to rounding treatment.
In a preferred embodiment of the present invention, the height of the magnetic rod sleeve is mm ±. mm.
Compared with the prior art, the invention has the beneficial effects that:
1. in this scheme, thereby it can carry out mutual joint to make latch mechanism through the latch mechanism that is provided with to make the connecting plate can carry out the joint with another group and fix, and then further make the bar cover can make up better and the fixed of connecting plate, thereby make equipment can strengthen the combined function and the dismantlement function of connecting plate better.
2. In this scheme, through pressing trapezoidal button to make second trapezoidal plate and first trapezoidal plate slide to keeping away from the end mutually, thereby make V type groove and another clamping mechanism of organizing carry out the joint fixed, thereby make the connecting plate can carry out the combined action better.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a first perspective view of the present invention;
FIG. 2 is a second perspective view of the present invention;
FIG. 3 is a first partial exploded view of the present invention;
FIG. 4 is a second partial exploded view of the present invention;
FIG. 5 is a partial exploded view of the concave card of the present invention;
fig. 6 is a partial exploded view of the trapezoidal button of the present invention.
In the figure: 1. a connecting plate; 2. a slot; 3. a magnetic rod sleeve; 4. a rectangular groove; 5. a first circular groove; 6. a first trapezoidal plate; 7. a first connecting column; 8. a hollow cylinder; 9. a V-shaped clamping block; 10. a second trapezoidal plate; 11. a second connecting column; 12. a first spring; 13. a V-shaped groove; 14. a trapezoidal button; 15. an arc-shaped slot; 16. a limiting rod; 17. a second circular groove; 18. a concave card board; 19. e-shaped fixture blocks; 20. a third circular groove; 21. reinforcing ribs; 22. a second spring.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1
Referring to fig. 1-6, the present invention provides the following technical solutions:
a high utility magnet sleeve comprising:
a connecting plate 1;
a rectangular groove 4; the upper end of the connecting plate 1 is provided with a rectangular groove 4, the upper end of the connecting plate 1 is provided with a slot 2, and the side end of the connecting plate 1 is provided with a first circular groove 5; and
clamping mechanism, clamping mechanism includes first trapezoidal plate 6, second trapezoidal plate 10, second spliced pole 11, first spliced pole 7, V type groove 13, hollow section of thick bamboo 8 and V type fixture block 9, first trapezoidal plate 6 and the equal sliding connection of second spliced pole 11 are in rectangular channel 4, 11 fixed connection of second spliced pole is in the side of second trapezoidal plate 10, first spliced pole 7 fixed connection is in the side of first trapezoidal plate 6, the side of second spliced pole 11 is seted up in V type groove 13, hollow section of thick bamboo 8 fixed connection is in the side of first spliced pole 7, V type fixture block 9 fixed connection is in hollow section of thick bamboo 8.
In the embodiment of the invention, the connecting plate 1 is made of corrosion-resistant material, so that when the connecting plate 1 is used for placing the magnetic rod sleeve 3, the magnetic rod sleeve 3 can be better ensured to be fixed, the equipment is more stable, the rectangular groove 4 can better fix the clamping mechanism, so that the clamping mechanism can better push the first trapezoidal plate 6 and the second trapezoidal plate 10, the clamping mechanism can be clamped with each other through the arranged clamping mechanism, so that the connecting plate 1 can be clamped and fixed with another group, and further the magnetic rod sleeve can be better combined and fixed with the connecting plate 1, so that the equipment can better enhance the combining function and the disassembling function of the connecting plate 1, wherein the first trapezoidal plate 6 can fix the first connecting column 7, second trapezoidal plate 10 plays the realization and carries out the fixed action with second spliced pole 11, first spliced pole 7 plays the realization and carries out the fixed action with hollow section of thick bamboo 8, hollow section of thick bamboo 8 plays the realization and carries out the fixed action with V type fixture block 9, wherein the material of hollow section of thick bamboo 8 can adopt recoverable plastics to make, thereby make hollow section of thick bamboo 8 after using for a long time, make hollow section of thick bamboo 8 can possess the environmental protection function better when needs are replaced, V type groove 13 plays and realizes after second spliced pole 11 carries out the joint through with V type fixture block 9, can carry out the fixed action with connecting plate 1 better.
Specifically, referring to fig. 1-6, a third circular groove 20 is formed at a side end of the rectangular groove 4, a trapezoidal button 14 is slidably connected to an end of the first trapezoidal plate 6 close to the second trapezoidal plate 10, an arc-shaped groove 15 is formed at a side end of the trapezoidal button 14, a limiting rod 16 is disposed in the arc-shaped groove 15, and a side end of the limiting rod 16 is fixedly connected to the third circular groove 20.
In this embodiment: third circular slot 20 plays the realization and carries out the fixed action with gag lever post 16, after fixing gag lever post 16 through third circular slot 20, thereby it is spacing to make gag lever post 16 can be better with trapezoidal button 14, trapezoidal button 14 plays the realization and slides first trapezoidal plate 6 and second trapezoidal plate 10, through pressing trapezoidal button 14, thereby it slides to keeping away from the end mutually to make second trapezoidal plate 10 and first trapezoidal plate 6, thereby it is fixed to make V type groove 13 carry out the joint with another set of latch mechanism, thereby make connecting plate 1 can make up the effect better.
Specifically, referring to the figure, the circumferential surface of the second connecting column 11 is sleeved with a first spring 12, and one side end of the first spring 12 is connected with one side end of the rectangular groove 4.
In this embodiment: first spring 12 plays the realization and carries out concertina movement after second spliced pole 11, thereby makes second spliced pole 11 can reset better through the flexible of first spring 12 to realize that equipment can separate better after the combination, be connected through a side of first spring 12 and a side of rectangular channel 4, thereby make second spliced pole 11's stability further promote.
Specifically referring to fig. 2 and 6, the second spring 22 is sleeved on the circumferential surface of the first connecting post 7, and one side end of the second spring 22 is connected to the other side end of the rectangular groove 4, so as to further improve the stability of the device and enhance the practicability of the device.
In this embodiment: second spring 22 plays the realization and after first spliced pole 7 carries out concertina movement, thereby make first spliced pole 7 can reset better through the flexible of second spring 22, thereby realize that equipment can separate better after the combination, be connected with another side of first trapezoidal plate 6 through a side of second spring 22, thereby make the stability of first spliced pole 7 further promote, and then further promote the stability of equipment, the practicality of reinforcing equipment.
Specifically, referring to fig. 3 and 4, the magnetic rod sleeve 3 is movably clamped in the slot 2, and the circumferential surface of the magnetic rod sleeve 3 is fixedly connected with the reinforcing rib 21.
In this embodiment: the magnetic rod sleeve 3 is made of corrosion-resistant recyclable materials, so that the service life of the magnetic rod sleeve 3 is further prolonged, and the magnetic rod sleeve 3 is made of recyclable materials, so that the equipment is more environment-friendly and the practicability of the equipment is further improved.
Specifically referring to fig. 3 and 5, a second circular groove 17 is formed at a side end of the connecting plate 1, a concave clamping plate 18 is fixedly connected inside the second circular groove 17, and an E-shaped clamping block 19 is movably clamped at a side end of the second circular groove 17.
In this embodiment: second circular slot 17 plays and fixes concave cardboard 18 better, thereby fixes concave cardboard 18 through second circular slot 17 and makes the stability of concave cardboard 18 further promote, and then makes equipment strengthen its stability better when using, and concave cardboard 18 plays and realizes carrying out the joint with E type fixture block 19 and can be connected with the outside better and fixed function later.
Specifically, referring to fig. 1 and 5, the concave clip plate 18 and the E-shaped clip plate 19 can be replaced, and the surface of the connecting plate 1 is rounded.
In this embodiment: the concave clamping plate 18 and the E-shaped clamping block 19 can be replaced, so that the device can be better convenient to disassemble and assemble in use, and the practicability of the device and the functionality of the device are further improved.
Specifically, referring to fig. 2, the height of the magnetic rod sleeve 3 is 23mm ± 0.02 mm.
In this embodiment: the height of the magnetic rod sleeve 3 is 23mm +/-0.02 mm, so that the magnetic rod sleeve 3 can be used by workers better and conveniently when in use, and the practicability of the magnetic rod sleeve 3 and the functionality of the magnetic rod sleeve 3 are further improved.
The working principle and the using process of the invention are as follows: firstly, the magnetic rod sleeve 3 is clamped in the slot 2, then the second circular groove 17 arranged at the side end of the connecting plate 1 is connected with the concave clamping plate 18, then the V-shaped clamping block 9 is clamped, at the moment, the V-shaped clamping block 9 can be fixed with the outside, when a plurality of groups of the connecting plate 1 need to be combined, a plurality of groups of the connecting plate 1 can be clamped, at the moment, two groups of clamping mechanisms are matched, at the moment, the trapezoidal button 14 is pressed, at the moment, the second trapezoidal plate 10 and the first trapezoidal plate 6 slide towards the far end, at the moment, the first spring 12 and the second spring 22 slide, at the moment, the V-shaped clamping block 9 and the V-shaped groove 13 are matched, at the moment, the clamping function of the equipment is completed, the clamping mechanisms can be mutually clamped through the arranged clamping mechanisms, so that the connecting plate 1 can be clamped and fixed with another group, and further, the magnetic rod sleeve can be better combined and fixed on the connecting plate 1, so that the device can better enhance the combining function and the disassembling function of the connecting plate 1.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (8)

1. A magnetic rod sleeve with high practicability is characterized by comprising:
a connecting plate (1);
a rectangular groove (4); the upper end of the connecting plate (1) is provided with a rectangular groove (4), the upper end of the connecting plate (1) is provided with a slot (2), and the side end of the connecting plate (1) is provided with a first circular groove (5); and
clamping mechanism, clamping mechanism includes first trapezoidal plate (6), second trapezoidal plate (10), second spliced pole (11), first spliced pole (7), V type groove (13), hollow section of thick bamboo (8) and V type fixture block (9), equal sliding connection in rectangular channel (4) of first trapezoidal plate (6) and second spliced pole (11), second spliced pole (11) fixed connection is in the side of second trapezoidal plate (10), first spliced pole (7) fixed connection is in the side of first trapezoidal plate (6), the side of second spliced pole (11) is seted up in V type groove (13), hollow section of thick bamboo (8) fixed connection is in the side of first spliced pole (7), V type fixture block (9) fixed connection is in hollow section of thick bamboo (8).
2. The high utility magnetic sleeve as claimed in claim 1, wherein: third circular slot (20) have been seted up to the side of rectangular channel (4), the end sliding connection that is close to mutually of first trapezoidal plate (6) and second trapezoidal plate (10) has trapezoidal button (14), arc wall (15) have been seted up to the side of trapezoidal button (14), be provided with gag lever post (16) in arc wall (15), the side fixed connection of gag lever post (16) is in third circular slot (20).
3. A highly practical magnet rod sleeve according to claim 2, wherein: the circumference surface of the second connecting column (11) is sleeved with a first spring (12), and one side end of the first spring (12) is connected with one side end of the rectangular groove (4).
4. A practical magnet rod sleeve according to claim 3, wherein: the circumferential surface of the first connecting column (7) is sleeved with a second spring (22), and one side end of the second spring (22) is connected with the other side end of the rectangular groove (4).
5. The high utility magnetic rod sleeve according to claim 4, wherein: the magnetic rod sleeve (3) is movably clamped in the slot (2), and reinforcing ribs (21) are fixedly connected to the circumferential surface of the magnetic rod sleeve (3).
6. The high utility magnetic rod sleeve according to claim 5, wherein: the side end of the connecting plate (1) is provided with a second circular groove (17), a concave clamping plate (18) is fixedly connected to the inside of the second circular groove (17), and an E-shaped clamping block (19) is movably clamped at the side end of the second circular groove (17).
7. The high utility magnetic rod sleeve according to claim 6, wherein: the concave clamping plate (18) and the E-shaped clamping block (19) can be replaced, and the surface of the connecting plate (1) is subjected to rounding treatment.
8. The utility model discloses a high practicality bar cover of claim 7, characterized by: the height of the magnetic rod sleeve (3) is 23mm +/-0.02 mm.
CN202111366890.4A 2021-11-18 2021-11-18 Magnetic rod sleeve with high practicability Pending CN114231385A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111366890.4A CN114231385A (en) 2021-11-18 2021-11-18 Magnetic rod sleeve with high practicability

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111366890.4A CN114231385A (en) 2021-11-18 2021-11-18 Magnetic rod sleeve with high practicability

Publications (1)

Publication Number Publication Date
CN114231385A true CN114231385A (en) 2022-03-25

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CN202111366890.4A Pending CN114231385A (en) 2021-11-18 2021-11-18 Magnetic rod sleeve with high practicability

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015062549A1 (en) * 2013-11-01 2015-05-07 利多(香港)有限公司 Nucleic acid extraction device
CN212293552U (en) * 2020-04-29 2021-01-05 海南科晶生物技术有限公司 PCR tube
CN214203101U (en) * 2021-01-21 2021-09-14 赵阳 Adjustable simulation display board for system integration
CN214529058U (en) * 2021-02-05 2021-10-29 厦门甄准生物技术有限公司 Nucleic acid extraction magnetic rod sleeve and extraction device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015062549A1 (en) * 2013-11-01 2015-05-07 利多(香港)有限公司 Nucleic acid extraction device
CN212293552U (en) * 2020-04-29 2021-01-05 海南科晶生物技术有限公司 PCR tube
CN214203101U (en) * 2021-01-21 2021-09-14 赵阳 Adjustable simulation display board for system integration
CN214529058U (en) * 2021-02-05 2021-10-29 厦门甄准生物技术有限公司 Nucleic acid extraction magnetic rod sleeve and extraction device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张开慧;: "新一代的磁珠法核酸自动提取仪研究进展", 甘肃畜牧兽医, vol. 49, no. 04, pages 53 - 56 *

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Application publication date: 20220325