CN207444137U - A kind of tissue block freezing device - Google Patents

Abstract

The utility model discloses a kind of tissue block freezing devices, including cryopreservation tube, a casing that can be taken off are provided in the cryopreservation tube, described sleeve pipe is interior to be arranged to multiple parking spaces for being used to store tissue block, and a described sleeve pipe generally engraved structure along its axial direction.The utility model in cryopreservation tube by being equipped with sleeve, and it is divided into the parking space of several storage tissue blocks in casing, it is uniformly stored in each layer parking space so that tissue block can separate, so as to ensure that tissue block comes into full contact with interior cryopreservation tube frozen stock solution, it avoids a large amount of deposited tube bottoms of tissue block that from cannot coming into full contact with frozen stock solution, causes the unnecessary damage of tissue block.

Description

A kind of tissue block freezing device

Technical field

The utility model is related to cryopreservation device design fields, and in particular to a kind of tissue block freezing device.

Background technology

Stem cell is the cell of a kind of ability and multinomial differentiation potential with self-renewing.Under certain condition, it can To be divided into multiple functions cell, there is the potential function for regenerating various histoorgans and human body.The tissue-derived of stem cell has Very much, including umbilical cord, Cord blood, tooth, menstrual blood, placenta, amnion and fat etc..

Stem cell rich content in umbilical cord tissue is valuable Biological information resources.To ensure the stem cell in umbilical cord tissue Activity is put into after need to umbilical cord tissue being cut into 0.1-0.3 cubic millimeters of tissue block in tissue freezing solution, long-term in liquid nitrogen container It preserves.Umbilical cord tissue block is placed in common cryopreservation tube at present, and tissue block can sink to tube bottom, is unfavorable for tissue block and is come into full contact with group Frozen stock solution is knitted, which is badly in need of solving, and ensures the quality of storage tissue.

Utility model content

The problem of for being proposed in background technology, the utility model provides a kind of tissue block freezing device, including freezing Pipe, is provided with a casing that can be taken off in the cryopreservation tube, is arranged in described sleeve pipe along its axial direction multiple for storing tissue The parking space of block, and a described sleeve pipe generally engraved structure.

It is preferred that it is provided with to pick and place the opening of the tissue block on described sleeve pipe side wall.

It is preferred that be additionally provided with enabling in the opening, each parking space be equipped with there are one opening the door or Multiple parking spaces share an enabling.

It is preferred that the caliber of described sleeve pipe is less than the caliber of the cryopreservation tube, the pipe range of described sleeve pipe is less than described freeze The pipe range of pipe.

It is preferred that the hollow out hole in described sleeve pipe is less than the size of the tissue block.

It is preferred that described sleeve pipe and cryopreservation tube are made of low-temperature resistance plastics.

It is preferred that the cryopreservation tube is made of pipe shaft and pipe lid.

It is preferred that frozen stock solution is housed in the cryopreservation tube.

The utility model due to using the technology described above, is allowed to compared with prior art, have the following advantages that and accumulate Pole effect：

Tissue block freezing device provided by the utility model, is equipped with sleeve in cryopreservation tube, and if being divided into casing The parking space of dry storage tissue block, is uniformly stored in so that tissue block can separate in each layer parking space, so as to It ensure that tissue block comes into full contact with interior cryopreservation tube frozen stock solution, avoid a large amount of deposited tube bottoms of tissue block that from cannot coming into full contact with and freeze Liquid causes the unnecessary damage of tissue block.

Description of the drawings

With reference to attached drawing, pass through the above-mentioned and other spy for stating detailed description, being more clearly understood that the utility model hereafter It seeks peace advantage, wherein：

Fig. 1 is the structure diagram of tissue block freezing device provided by the utility model；

Fig. 2 is the structure diagram of the utility model middle sleeve.

Symbol description：

1- pipe shafts

2- pipe lids

3- casings

4- opens the door

Specific embodiment

Referring to the attached drawing for showing the utility model embodiment, the utility model is described in more detail.However, this reality It can be realized in many different forms with new, and should not be construed as being limited by the embodiment herein proposed.On the contrary, it proposes These embodiments be in order to reach fully and complete disclosure, and make those skilled in the art understand completely this practicality newly The scope of type.In these attached drawings, for clarity, the size and relative size in layer and region may be exaggerated.

With reference to Fig. 1-2, the utility model provides a kind of tissue block freezing device, including cryopreservation tube, is set in cryopreservation tube There is a casing 3 that can be taken off, casing 3 is interior to be arranged to multiple parking spaces for being used to store tissue block along its axial direction, and casing 3 is whole Body is an engraved structure.

The utility model is equipped with sleeve in cryopreservation tube, and the storage for being divided into several storage tissue blocks in casing is empty Between so that tissue block can separate uniformly be stored in each layer parking space, ensure that tissue block come into full contact in Cryopreservation tube frozen stock solution avoids a large amount of deposited tube bottoms of tissue block that from cannot coming into full contact with frozen stock solution, causes the unnecessary damage of tissue block.

Tissue block freezing device provided by the utility model can be used for storing umbilical cord tissue block, placenta tissue block, amnion The various organizations such as tissue block, liver organization block, renal tissue block, are not limited herein.

In the present embodiment, cryopreservation tube is made of the pipe lid 2 that pipe shaft 1 and lid are located in 1 upper end opening of pipe shaft, built with Frozen stock solution；Cryopreservation tube can directly use cryopreservation tube of the prior art, not be limited herein.

In the present embodiment, the caliber of casing 3 is less than the caliber of cryopreservation tube, and the pipe range of casing 3 is again smaller than the pipe of cryopreservation tube It is long, consequently facilitating casing is smoothly encased in cryopreservation tube.Moreover, casing 3 is an engraved structure, it can be by opening up several holes Etc. modes realize；3 hollow out of casing sets to ensure casing 3 as after in cryopreservation tube, and the frozen stock solution in casing 3 is via hollow-out parts It is flowed into the parking space of each layer of casing；Further, the hollow out hole on casing 3 is less than the size of tissue block, so as to anti- Only tissue block leaks out casing and is packed together.

In the present embodiment, the number of plies of the parking space formed in casing 3 is at least two layers, can be according to the big of cryopreservation tube pipe It is small to wait because usually setting, it is not limited herein, such as shown in Fig. 1, the parking space that is of five storeys is set in casing 3.

Further, 3 side wall of casing each stores sky and is additionally provided with to pick and place the opening of tissue block, is provided in opening It opens the door, opens the door and open tissue block being placed into cryopreservation tube；Wherein, since entire cryopreservation device is smaller, in the present embodiment In opening on each layer parking space share one and open the door 4.Certainly, each parking space can also match somebody with somebody respectively in other embodiments It opens the door there are one standby, is not limited herein.

In the present embodiment, casing 3 and cryopreservation tube are made of low-temperature resistance plastics.

Below with regard to the operation principle of tissue block freezing device provided by the utility model, it is further described：

First, casing is taken out and is placed in sterile plate, the enabling on sleeve side walls is opened with aseptic nipper, by tissue Block, which is put into, to be uniformly placed into the parking space of each layer, turns off the enabling on side wall；

Casing is put into cryopreservation tube, frozen stock solution is added in, tightens pipe lid；Cryopreservation tube is put into program temperature reduction box -80 DEG C Overnight, it is then transferred in liquid nitrogen container after a period of time and preserves for a long time.

Those skilled in the art should be understood that the utility model can be realized with many other concrete forms without de- Spirit or scope from itself.Although the case study on implementation of the utility model has been described, it should be understood that the utility model should not limit Be made as these embodiments, those skilled in the art can as defined by the following claims the spirit of the utility model and Within the scope of make change and modification.

Claims (8)

1. a kind of tissue block freezing device, which is characterized in that including cryopreservation tube, a set that can be taken off is provided in the cryopreservation tube Pipe, described sleeve pipe is interior to be arranged to multiple parking spaces for being used to store tissue block along its axial direction, and described sleeve pipe generally one is engraved Hollow structure.

2. tissue block freezing device according to claim 1, which is characterized in that be provided with to take on described sleeve pipe side wall Put the opening of the tissue block.

3. tissue block freezing device according to claim 2, which is characterized in that enabling is additionally provided in the opening, often A parking space be equipped with there are one open the door or multiple parking spaces to share an enabling.

4. tissue block freezing device according to claim 1, which is characterized in that the caliber of described sleeve pipe is less than described freeze The caliber of pipe, the pipe range of described sleeve pipe are less than the pipe range of the cryopreservation tube.

5. tissue block freezing device according to claim 1, which is characterized in that the hollow out hole in described sleeve pipe is less than institute State the size of tissue block.

6. tissue block freezing device according to claim 1, which is characterized in that described sleeve pipe and cryopreservation tube are using anti-low Warm plastics are made.

7. tissue block freezing device according to claim 1, which is characterized in that the cryopreservation tube is by pipe shaft and pipe lid structure Into.

8. tissue block freezing device according to claim 1, which is characterized in that frozen stock solution is housed in the cryopreservation tube.