CN207081735U

CN207081735U - A kind of biological chip reading apparatus

Info

Publication number: CN207081735U
Application number: CN201720738963.0U
Authority: CN
Inventors: 艾平发; 胡楠; 李涛; 黎稳
Original assignee: Zhongshan Core Biotechnology Co Ltd
Current assignee: Zhongshan Core Biotechnology Co Ltd
Priority date: 2017-06-22
Filing date: 2017-06-22
Publication date: 2018-03-09
Anticipated expiration: 2027-06-22

Abstract

The utility model discloses a kind of biological chip reading apparatus, including support, liquid-transfering gun, first drive mechanism, material component, reagent refrigerating device, it is arranged at the material component and multiple chip incubating devices at the reagent refrigerating device rear, needle device is washed with what the multiple chip incubating device was disposed adjacent, it is set up in the multiple chip incubating device and the device for cleaning chip and its signal supervisory instrument washed above needle device, for driving the second drive mechanism of the device for cleaning chip and the signal supervisory instrument back and forth movement, and it is arranged at the syringe needle collection device and waste collecting device of work top bottom.With this structure design, by under the driving effect of the first drive mechanism and the second drive mechanism, the a series of activities such as making, incubation, test and the cleaning of chip sample can be automatically performed, chip testing efficiency is greatly improved, effectively reduces test job amount.

Description

A kind of biological chip reading apparatus

Technical field

It the utility model is related to biochip technical field of measurement and test, more particularly to a kind of biological chip reading apparatus.

Background technology

Biological chip testing technology, it is fixed on using fluorescence, biotin or other method mark on bio-chip substrate Biomolecule (such as DNA, RNA, protein molecular, antigen, antibody) target, and will be marked by building some special detection means Note signal changes into the view data for being available for analyzing and processing, to obtain and analyze the life of the biomolecule on biochip The various information such as thing, physics, chemistry, the time of day of diagnostic biomolecule.

Biochip test equipment is widely used in the fields such as scientific research, medicine, health, is to be used to catch and handle biological core The instrument of piece image, traditional biochip supplies analysis have the following disadvantages：(1) automaticities are low, so that surveying Try less efficient.(2) lacks necessary chip incubating device and cleaning device, can not be efficiently incubated, after use Device is fast and effectively cleaned, so that cleaning efficiency is not high and not clean enough, and then to cause when reusing Test result produces error.

Utility model content

The purpose of this utility model is to provide a kind of automaticity height, time saving and energy saving biological chip reading apparatus.

To use following technical scheme up to this purpose, the utility model：

A kind of biological chip reading apparatus, including support, set up with the support above liquid-transfering gun, for driving the shifting The first multi-shaft interlocked drive mechanism of liquid rifle, be arranged at the support work top material component, with the material component The reagent refrigerating device that is disposed adjacent, it is arranged at the material component and multiple chips at the reagent refrigerating device rear are incubated Device, be disposed adjacent with the multiple chip incubating device wash needle device, be set up in the multiple chip incubating device and wash Device for cleaning chip and its signal supervisory instrument above needle device, for driving the device for cleaning chip and the signal to examine Survey the second drive mechanism of device back and forth movement and be arranged at the syringe needle collection device and waste collection of work top bottom Device.

Wherein, the material component include sample loading device, be arranged at the sample loading device side dilution position, And the syringe needle box of the dilution position side is arranged at, the side of the syringe needle box is provided with reagent refrigerating device.

Wherein, first drive mechanism includes first slide rail and institute of the parallel shelf located at the support two lateral walls The first slide rail is stated to slide the second slide rail set and come and go the liquid-transfering gun slided along the second slide rail length direction, First slide rail is set along the support Y direction, and second slide rail is set along the support X-direction.

Wherein, second drive device includes threeth cunning of the parallel shelf located at the multiple chip incubating device both ends Rail, and the portal frame being slidably matched with the 3rd slide rail, the device for cleaning chip and signal supervisory instrument difference It is arranged at the both sides of the crossbeam of the portal frame.

Wherein, the cross rail top of the portal frame is provided with first for driving the device for cleaning chip up and down motion Motor, and the second motor for driving the signal supervisory instrument to move up and down.

Wherein, the device for cleaning chip includes being connected with first motor fixed mount, along the fixation Frame one side short transverse slides up and down the wiper mechanism of setting and is arranged between the wiper mechanism and the fixed mount Bolster；The wiper mechanism includes purge block, and is arranged at the purge block bottom surface and along the cleaning block length The uniform cleaning needle in direction and waste liquid pin, the cleaning needle penetrate with penetrating the cleaning chamber set along the purge block length direction Set, the waste liquid pin is set with penetrating the waste liquid chamber set insertion along the purge block length direction, the cleaning chamber and institute State waste liquid chamber to connect with corresponding external pump body phase, the both ends of the fixed mount one side are respectively along the fixed mount height side To guide pillar is provided with, the purge block is slided with the guide pillar and set, and the bolster is arranged to spring, and the bolster is arranged In one end of the guide pillar and inconsistent with the upper side of the purge block and/or downside.

Wherein, the signal supervisory instrument includes the test bracket with second motor fastening, and is set up in Test probe assembly in the cavity of the test bracket；A test bracket at least cavity wall can with the test bracket Dismantling connection, the cavity top of the test bracket offers along the test bracket length direction to be visited for adjusting the test The elongated slot of needle assemblies installation site；The test probe assembly includes two probe fixed plates, the setting that upper and lower parallel interval is set Support column between two probe fixed plate, along the uniform probe of the two probe fixed plates length direction and level It is arranged at the limiting plate of multiple probe bottoms；The support column is arranged in pairs two in two probe fixed plate respectively End, and the probe fixed plate positioned at the top fastens with the screw rod being arranged in the elongated slot.

Wherein, the chip incubating device includes being incubated platform, the heating plate for being embedded in the incubation platform bottom and temperature spy Head, the 3rd drive mechanism for being arranged at described incubation platform one end, and be connected with the drive shaft of the 3rd drive mechanism Lid is incubated, round slide of platform length direction is incubated described in the incubation cover rim and is set；3rd drive mechanism includes being anchored on The supporting plate for being incubated you portion, the guide rail set along the supporting plate length direction, the supporting plate is arranged at away from institute The one end for stating incubation platform is provided with stepper motor and the round silk braid for sliding setting of drive screw along the stepper motor, The silk braid fastens with the end for being incubated lid, and the lid that is incubated fastens with the sliding block that the guide rail is slidably matched.

Wherein, the reagent refrigerating device includes refrigerating box, the refrigeration lid being arranged at the top of the refrigerating box, is arranged at institute Refrigerating box side is stated to be used for the 4th drive mechanism of the refrigeration lid automatic open-close and be arranged at the system of the refrigerating box bottom Cold structure, a side wall of the refrigeration lid and the refrigerating box are hinged；The refrigerating box is provided with multiple refrigeration cavitys, described Refrigerate and be provided through osculum between the bottom of cavity and the side wall of the refrigerating box；The refrigeration mechanism includes being brought into close contact Cooling piece in the refrigerating box bottom surface, the fin being arranged at below the cooling piece and it is arranged at the fin The fan of lower section.

Wherein, the needle device of washing includes cleaning block body, the useless of setting is penetrated along the purge block body length direction Sap cavity and water-injecting cavity and multiple clean-out openings along the purge block body length direction uniformly, the clean-out opening are arranged at institute The top of cleaning block body is stated, the multiple clean-out opening is set with the waste liquid chamber and water-injecting cavity insertion, the clean-out opening bag Include along the first clean-out opening for being vertically arranged of cleaning block body, and be arranged at the first clean-out opening bottom hole and with the waste liquid chamber The second clean-out opening set is penetrated, the diameter of first clean-out opening is more than the diameter of second clean-out opening, and described first is clear The bottom hole of hole flushing is provided with the sphere being engaged with being sheathed on the bulb stopper of waste liquid pin periphery.

The beneficial effects of the utility model：The utility model includes support, set up and the liquid-transfering gun above the support, use In drive the first multi-shaft interlocked drive mechanism of the liquid-transfering gun, be arranged at the support work top material component, with Reagent refrigerating device that the material component is disposed adjacent, it is arranged at the material component and the reagent refrigerating device rear Multiple chip incubating devices, be disposed adjacent with the multiple chip incubating device wash needle device, be set up in the multiple chip Incubating device and the device for cleaning chip washed above needle device and its signal supervisory instrument, for driving the device for cleaning chip With the second drive mechanism of the signal supervisory instrument back and forth movement and it is arranged at the syringe needle collection device of work top bottom And waste collecting device., can by under the driving effect of the first drive mechanism and the second drive mechanism with this structure design The a series of activities such as making, incubation, test and the cleaning of chip sample are automatically performed, are greatly improved chip testing effect Rate, effectively reduce test job amount.

Brief description of the drawings

Fig. 1 is a kind of axonometric drawing of biological chip reading apparatus of the utility model.

Fig. 2 is the axonometric drawing of the second drive mechanism in Fig. 1.

Fig. 3 is the axonometric drawing of Fig. 1 chips cleaning devices.

Fig. 4 is the axonometric drawing of signal supervisory instrument in Fig. 1.

Fig. 5 is the axonometric drawing of Fig. 1 chips incubating devices.

Fig. 6 is the axonometric drawing of reagent cold storage plant in Fig. 1.

Fig. 7 is the front view that needle device is washed in Fig. 1.

Fig. 8 is the sectional view in AA sections in Fig. 7.

Fig. 9 is the axonometric drawing that needle device is washed in Fig. 1.

Figure 10 is the axonometric drawing of waste collecting device in Fig. 1.

Embodiment

Further illustrate the technical solution of the utility model below in conjunction with the accompanying drawings and by embodiment.

As shown in Figure 1 to Figure 2, a kind of biological chip reading apparatus in the present embodiment, including support 1, erection and the support 1 The liquid-transfering gun 2 of top, the work for driving the first multi-shaft interlocked drive mechanism 3 of the liquid-transfering gun 2, being arranged at the support 1 The material component for making table top, the reagent refrigerating device 4 being disposed adjacent with the material component, it is arranged at the material component and institute State multiple chip incubating devices 5 at the rear of reagent refrigerating device 4, wash pin with what the multiple chip incubating device 5 was disposed adjacent Device 6, the device for cleaning chip 8 for being set up in the multiple chip incubating device 5 and washing the top of needle device 6 and its signal detection dress Put 7, the second drive mechanism 9 for driving device for cleaning chip 8 and the signal supervisory instrument 7 back and forth movement and It is arranged at the syringe needle collection device 11 and waste collecting device 12 of work top bottom.

Specifically, the material component includes sample loading device 13, is arranged at the side of sample loading device 13 Dilution position 14 and the syringe needle box 15 for being arranged at the dilution position side, the side of the syringe needle box 15 is provided with reagent refrigerating Device 4.

In the present embodiment, as shown in figure 1, first drive mechanism 3 is located at the opposite sides of support 1 including parallel shelf First slide rail 31 of wall, the second slide rail 32 for setting is slided with first slide rail 31 and along the length of the second slide rail 32 Direction comes and goes the liquid-transfering gun 2 slided, and Y direction of first slide rail 31 along the support 1 is set, second slide rail 32 are set along the X-direction of the support 1, afterwards with reference to the up and down motion of liquid-transfering gun, realize liquid-transfering gun above support table top Three-shaft linkage.

With reference to shown in Fig. 2, second drive device includes parallel shelf located at the multiple both ends of chip incubating device 5 3rd slide rail 91, and the portal frame 92 being slidably matched with the 3rd slide rail, the device for cleaning chip 8 and signal inspection The both sides that device 7 is respectively arranged at the crossbeam of the portal frame are surveyed, further, the cross rail top of the portal frame 92 is provided with For the first motor 93 for driving the device for cleaning chip 8 to move up and down, and for driving the signal detection to fill Put the second motor 94 of 7 up and down motions.In the present embodiment, the side relative with the 3rd slide rail 91 is provided with for portal frame The guide rod 95 slided is come and gone, the effect for the timing belt that portal frame is driven by the 3rd motor 97 of driving is past along the 3rd slide rail Return motion.The setting of first motor 93 and the second motor 94, realizes device for cleaning chip 8 and signal detection respectively The up and down motion of device 7.It will not be described here.

With reference to shown in Fig. 3, the device for cleaning chip 8 include be connected with first motor fixed mount 81, The wiper mechanism 82 of setting is slided up and down along the one side short transverse of fixed mount 81 and is arranged at the wiper mechanism 82 Bolster 83 between the fixed mount；The wiper mechanism 82 includes purge block 821, and is arranged at the purge block 821 bottom surfaces and along the length direction of purge block 821 uniform cleaning needle 822 and waste liquid pin 823, the cleaning needle 822 with The cleaning chamber 824 set along the length direction of purge block 821 insertion, which penetrates, to be set, the waste liquid pin 823 with along the cleaning The length direction of block 821 insertion set waste liquid chamber 825 insertion set, it is described cleaning chamber 824 and the waste liquid chamber 825 with it is corresponding External pump body phase connection, the both ends of the one side of fixed mount 81 are provided with guide pillar along the fixed mount short transverse respectively 84, the purge block 821 is slided with the guide pillar 84 and set, and the bolster 83 is arranged to spring, and the bolster 83 is arranged In one end of the guide pillar and inconsistent with the upper side of the purge block 821.

With reference to shown in Fig. 4, the signal supervisory instrument 7 includes the test bracket 71 with second motor fastening, And it is set up in the test probe assembly 72 in the cavity of the test bracket 71；The test bracket 71 has a cavity wall and institute State test bracket 71 to be detachably connected, offered at the top of the cavity of the test bracket 71 along the length direction of test bracket 71 For adjusting the elongated slot 711 of the test installation site of probe assembly 72；The test probe assembly 72 includes parallel up and down Two probe fixed plates 721 every setting, the support column 722 being arranged between two probe fixed plate 721, along two probe The uniform probe 723 of the length direction of fixed plate 721 and the limiting plate 724 for being horizontally placed on multiple probe bottoms；Institute Support column 722 is stated to be arranged in pairs respectively in the both ends of two probe fixed plate 721, and positioned at the probe fixed plate of the top 721 fasten with the screw rod being arranged in the elongated slot 711.With the signal supervisory instrument of this structure design, pass through test bracket Set, good shield effectiveness can be played to test probe assembly 72, can effectively strengthen test accuracy, meanwhile, test The setting of elongated slot in support, easily test probe assembly can be adjusted.

With reference to shown in Fig. 5 and Fig. 6, the chip incubating device 5 includes being incubated platform 51, is embedded in incubation platform 51 bottom Heating plate and temp probe, the 3rd drive mechanism 52 for being arranged at described incubation platform 51 one end, and with the described 3rd driving The incubation lid 53 that the drive shaft of mechanism 52 is connected, the incubation lid 53 come and go slip along incubation platform 51 length direction and set Put；3rd drive mechanism 52 includes being anchored on the supporting plate 521 of incubation platform 51 end, grown along the supporting plate 521 Degree direction set guide rail 522, be arranged at the supporting plate 521 away from it is described incubation platform 51 one end be provided with stepper motor 523 and along the stepper motor 523 drive screw 524 come and go slide set silk braid 525, the silk braid 525 with it is described The end fastening of lid 53 is incubated, the sliding block 526 that the incubation lid 53 is slidably matched with the guide rail 522 fastens.Set with this structure Meter, after chip to be tested is positioned over incubation platform, you can by being incubated the movement of lid, make chip to be tested be in a relative closure Cavity in, so as to accelerate the incubation efficiency of biochip to be measured.

With reference to shown in Fig. 6, the reagent refrigerating device 4 includes refrigerating box 41, is arranged at the cold of the top of refrigerating box 41 Hide lid 42, be arranged at the side of refrigerating box 41 for the 4th drive mechanism 43 for refrigerating the automatic open-close of lid 42, Yi Jishe The refrigeration mechanism 44 of the bottom of refrigerating box 41 is placed in, a side wall of the refrigeration lid 42 and the refrigerating box 41 is hinged；Institute State refrigerating box 41 and be provided with multiple refrigeration cavitys, run through between the bottom of the refrigeration cavity and the side wall of the refrigerating box 41 and set It is equipped with osculum；The refrigeration mechanism 44 includes being brought into close contact the cooling piece 441 in the bottom surface of refrigerating box 41, being arranged at institute State the fin 442 of the lower section of cooling piece 441 and be arranged at the fan 443 of the lower section of fin 442.In present embodiment, 4th drive mechanism is using motor driving timing belt, and then the folding for driving the mode of the jointed shaft of refrigeration lid to drive refrigeration to cover, It will not be described here.In present embodiment, osculum can be connected with external pump body phase, accelerate condensate liquid to outflow with this, prevent from tiring out Sewage or ice slag are formed after poly- in refrigeration chamber.

With reference to shown in Fig. 7 to Fig. 9, the needle device 6 of washing includes cleaning block body 61, cleans the length of block body 61 along described Waste liquid chamber 62 and water-injecting cavity 63 that direction insertion is set and multiple cleanings along cleaning block body 61 length direction uniformly Hole, the clean-out opening be arranged at it is described cleaning block body 61 top, the multiple clean-out opening with the waste liquid chamber 62 and note The insertion of water cavity 63 is set, and further, the clean-out opening includes the first clean-out opening 64 being vertically arranged along cleaning block body 61, with And the bottom hole of the first clean-out opening 64 and the second clean-out opening 65 set with the waste liquid chamber 62 insertion are arranged at, described first is clear The diameter of hole flushing 64 is more than the diameter of second clean-out opening 65, and the bottom hole of first clean-out opening 64 is provided with and be sheathed on useless The sphere 641 that the bulb stopper of liquid pin periphery is engaged, is flowed into waste water chamber for the ease of the water in water-injecting cavity, in the first clean-out opening 64 It is provided with through hole 66 in side wall between water-injecting cavity 63, in the present embodiment, waste liquid chamber 62 and water-injecting cavity 63 are respectively arranged with water Pump,, can be first by the first clean-out opening 64 corresponding to the insertion of multiple waste liquid pins when being cleaned to waste liquid pin with this structure design It is interior, and the bulb stopper of shank periphery and the sphere 641 of the bottom of the first clean-out opening 64 are brought into close contact, by being produced in waste liquid chamber 62 Negative pressure the waste liquid in waste liquid pin is emptied, and then by the through hole 66 in the side wall of the first clean-out opening 64 to the first clean-out opening Injected clear water in 64, outer surface of waste liquid pin is cleaned with this.

With reference to shown in Figure 10, cleaned to prevent from washing needle device 6, chip incubating device 5 and its device for cleaning chip 8 During sewage outflow to ground, washing needle device 6, multiple chip incubating devices 5 and its device for cleaning chip being arranged side by side 8 bottom sets waste collecting device 12, and the waste collecting device is arranged to the container that bottom surface is inclined to set, to cause sewage Flow to relatively low one end, and discharged by bottom discharge mouth 121.

Technical principle of the present utility model is described above in association with specific embodiment.These descriptions are intended merely to explain this reality With new principle, and the limitation to scope of protection of the utility model can not be construed in any way.Based on explanation herein, Those skilled in the art, which would not require any inventive effort, can associate other embodiments of the present utility model, These modes are fallen within the scope of protection of the utility model.

Claims

A kind of 1. biological chip reading apparatus, it is characterised in that：Including support, set up with the liquid-transfering gun above the support, be used for Drive the first multi-shaft interlocked drive mechanism of the liquid-transfering gun, be arranged at the support work top material component and institute State reagent refrigerating device that material component is disposed adjacent, be arranged at the material component and the reagent refrigerating device rear it is more Individual chip incubating device, be disposed adjacent with the multiple chip incubating device wash needle device, be set up in the multiple chip and incubate Educate device and the device for cleaning chip washed above needle device and its signal supervisory instrument, for drive the device for cleaning chip and Second drive mechanism of the signal supervisory instrument back and forth movement and be arranged at the syringe needle collection device of work top bottom with And waste collecting device.
A kind of 2. biological chip reading apparatus according to claim 1, it is characterised in that：The material component adds including sample Carry the dilution position for putting, being arranged at the sample loading device side and be arranged at the syringe needle box of the dilution position side, institute The side for stating syringe needle box is provided with reagent refrigerating device.
A kind of 3. biological chip reading apparatus according to claim 1, it is characterised in that：First drive mechanism includes flat Row is set up in the first slide rail of the support two lateral walls, slides the second slide rail set, Yi Jiyan with first slide rail The second slide rail length direction comes and goes the liquid-transfering gun slided, and first slide rail is set along the support Y direction, institute The second slide rail is stated to set along the support X-direction.
A kind of 4. biological chip reading apparatus according to claim 1, it is characterised in that：Second drive device includes flat Row is set up in the 3rd slide rail at the multiple chip incubating device both ends, and the gantry being slidably matched with the 3rd slide rail Frame, the device for cleaning chip and the signal supervisory instrument are respectively arranged at the both sides of the crossbeam of the portal frame.
A kind of 5. biological chip reading apparatus according to claim 4, it is characterised in that：The cross rail top of the portal frame is set The first motor for driving the device for cleaning chip to move up and down is equipped with, and for driving the signal detection to fill Put the second motor of up and down motion.
A kind of 6. biological chip reading apparatus according to claim 5, it is characterised in that：The device for cleaning chip include with Fixed mount that first motor is connected, the cleaning machine for sliding up and down along the fixed mount one side short transverse setting Structure and the bolster being arranged between the wiper mechanism and the fixed mount；The wiper mechanism includes purge block, and Be arranged at the purge block bottom surface and along the purge block length direction uniform cleaning needle and waste liquid pin, the cleaning needle with The cleaning chamber set along purge block length direction insertion, which penetrates, to be set, the waste liquid pin with along the purge block length direction The waste liquid chamber insertion that insertion is set is set, and the cleaning chamber and the waste liquid chamber connect with corresponding external pump body phase, described The both ends of fixed mount one side are provided with guide pillar along the fixed mount short transverse respectively, and the purge block is slided with the guide pillar Set, the bolster is arranged to spring, the bolster be sheathed on one end of the guide pillar and with the upside of the purge block Face and/or downside are inconsistent.
A kind of 7. biological chip reading apparatus according to claim 5, it is characterised in that：The signal supervisory instrument include with The test bracket of the second motor fastening, and the test probe assembly being set up in the cavity of the test bracket； A test bracket at least cavity wall is detachably connected with the test bracket, along institute at the top of the cavity of the test bracket Test bracket length direction is stated to offer for adjusting the elongated slot for testing probe assembly installation site；The test probe groups Part includes two probe fixed plates that upper and lower parallel interval sets, the support column being arranged between two probe fixed plate, along institute State the uniform probe of two probe fixed plate length directions and be horizontally placed on the limiting plate of multiple probe bottoms；Institute State support column to be arranged in pairs respectively in the both ends of two probe fixed plate, and be located at the probe fixed plate of the top with being arranged at Screw rod fastening in the elongated slot.
A kind of 8. biological chip reading apparatus according to claim 1, it is characterised in that：The chip incubating device includes incubating Educate platform, the heating plate for being embedded in the incubation platform bottom and temp probe, the 3rd driving machine for being arranged at described incubation platform one end Structure, and the incubation lid being connected with the drive shaft of the 3rd drive mechanism, incubation platform length side described in the incubation cover rim Set to round slide；3rd drive mechanism includes being anchored on the supporting plate in the incubation you portion, along the supporting plate Length direction set guide rail, be arranged at the supporting plate away from it is described incubation platform one end be provided with stepper motor, Yi Jiyan The drive screw of the stepper motor comes and goes the silk braid for sliding and setting, and the silk braid fastens with the end for being incubated lid, described Lid is incubated to fasten with the sliding block that the guide rail is slidably matched.
A kind of 9. biological chip reading apparatus according to claim 1, it is characterised in that：The reagent refrigerating device includes cold Hide case, the refrigeration lid being arranged at the top of the refrigerating box, be arranged at the refrigerating box side for the refrigeration lid automatic open-close The 4th drive mechanism and be arranged at the refrigeration mechanism of the refrigerating box bottom, the refrigeration lid and the one of the refrigerating box Side wall is hinged；The refrigerating box is provided with multiple refrigeration cavitys, the bottom of the refrigeration cavity and the side wall of the refrigerating box Between be provided through osculum；The refrigeration mechanism includes being brought into close contact the cooling piece in the refrigerating box bottom surface, set Fin below the cooling piece and the fan being arranged at below the fin.
A kind of 10. biological chip reading apparatus according to claim 1, it is characterised in that：The needle device of washing includes cleaning Block body, penetrate along the purge block body length direction waste liquid chamber set and water-injecting cavity and along the cleaning block body The uniform multiple clean-out openings of length direction, the clean-out opening are arranged at the top of the cleaning block body, the multiple clean-out opening Set with the waste liquid chamber and water-injecting cavity insertion, the clean-out opening includes the first cleaning being vertically arranged along cleaning block body Hole, and the first clean-out opening bottom hole and the second clean-out opening set with waste liquid chamber insertion are arranged at, described first is clear The diameter of hole flushing is more than the diameter of second clean-out opening, and the bottom hole of first clean-out opening is provided with and is sheathed on outside waste liquid pin The sphere that the bulb stopper enclosed is engaged.