CN105866451B - A kind of full-automatic specific protein analyzer - Google Patents
A kind of full-automatic specific protein analyzer Download PDFInfo
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- CN105866451B CN105866451B CN201610243861.1A CN201610243861A CN105866451B CN 105866451 B CN105866451 B CN 105866451B CN 201610243861 A CN201610243861 A CN 201610243861A CN 105866451 B CN105866451 B CN 105866451B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
Abstract
The present invention relates to the field of medical instrument technology, more particularly to a kind of full-automatic specific protein analyzer, including two pieces of support plates arranged in parallel, the sampling mechanism being arranged between two pieces of support plates, arranged on the upper end of two pieces of support plates and it is used for the longitudinal moving mechanism for driving sampling mechanism to move back and forth, arranged on longitudinal moving mechanism and it is used for the transverse moving mechanism for driving sampling mechanism to move left and right, base below sampling mechanism, it is installed in the sample apparatus for placing of the upper surface of base, it is installed in base and the testing agency for detecting sample, and for cleaning the fluid path rinse-system of sampling mechanism.The degree of automation of the full-automatic specific protein analyzer is high, can add sample and reagent automatically, and detects the percentage composition of the glycated protein in detected sample automatically.
Description
Technical field
The present invention relates to the field of medical instrument technology, and in particular to a kind of full-automatic specific protein analyzer.
Background technology
Specific protein analyzer is mainly used for each laboratory and the various albumen in sample is detected, and it is complete such as to detect vein
A variety of specific proteins in blood, peripheral blood, blood plasma, serum, urine, cerebrospinal fluid, saliva, including：Immune globulin, lgG subclass,
Complement, C reactive proteins（CRP）, antistreptolysin O（ASO）, rheumatoid factor（RF）, glycosylated hemoglobin
（HbA1c）, albumin（ALB）, microdose urine protein（MAB）, κ light chains and lambda light chain, ceruloplasmin（CER）, hoptoglobin
（HPT）, light railway albumen（TRF）, C1 inactivation factors（C1IN）, alpha1 Anti-trypsin（AAT）, prealbumin, serum and urine β 2
Microglobulin（BMG）, apolipoprotein（APO）, antithrombin Ⅲ（AT3）, 1 acidoglycoproteins of α（AAG）, alpha2 Macroglobulin
（AMG）Deng.By detecting increasing or lowering for these albumen, the diagnosis to doctor has highly important clinical meaning.It is specific
Protein analyzer accuracy is high, reproducible, either single sample or great amount of samples, can detect at any time, goes out knot immediately
Fruit.But existing specific protein analyzer in the sample loading alternative for carrying out using during sample-adding detection to sample is loaded with hand, is led to
Cross and manually sample is loaded.Reaction reagent and sample are added in cuvette with sample loading gun manually and manually shaken up again
Or stirrer is stirred after shaking up and detected again.This causes sample-adding process to be operated because artificial operation produces bigger difference
Journey is also complicated to the more demanding also so that detection process becomes slow of operating personnel, and when great amount of samples needs detection, meeting is serious
Influence detection speed.
The content of the invention
In order to overcome shortcoming and defect existing in the prior art, it is an object of the invention to provide a kind of full-automatic specific
Protein analyzer, the degree of automation of the full-automatic specific protein analyzer is high, can add sample and reagent automatically, and automatically
Detect the percentage composition of the glycated protein in detected sample.
The purpose of the present invention is achieved through the following technical solutions：A kind of full-automatic specific protein analyzer, including it is mutually flat
Two pieces of support plates that row is set, the sampling mechanism being arranged between two pieces of support plates, arranged on the upper end of two pieces of support plates and be used for
Drive the longitudinal moving mechanism of sampling mechanism back-and-forth motion, arranged on longitudinal moving mechanism and for driving sampling mechanism to move left and right
Transverse moving mechanism, the base below sampling mechanism, be installed in base upper surface sample apparatus for placing, be installed in
Base and for detecting the testing agency of sample and fluid path rinse-system for cleaning sampling mechanism.
Wherein, the sampling mechanism includes the sampling substrate arranged on the transverse moving mechanism, taking arranged on sampling substrate
Sample pipe and rabble and the sampling driving mechanism for driving probe tube and rabble to move up and down；The sampling driving machine
Structure includes the sampling motor for being respectively arranged on the sampling substrate top and bottom and sampling driven shaft and for driving probe tube
The sampling tooth band to move up and down with rabble, the end of the output terminal and sampling driven shaft that sample motor are connected with sampling gear,
Sampling tooth band is engaged on sampling gear.
Wherein, sampling mechanism further includes the sampling slide and stirring slide arranged on sampling substrate, and sampling slide and stirring are slided
Rail is arranged in parallel, and sampling slide slidably connects sampling sliding block, and the side of the sampling tooth band is connected with sampling sliding block, institute
State probe tube and be installed in sampling sliding block, stirring slide slidably connects stirring sliding block, samples the opposite side and stirring sliding block of tooth band
Connection, the rabble are installed in stirring sliding block；Positioning slide is equipped between sampling slide and stirring slide, positioning slide is with taking
Sample slide is parallel, and the right side opening for sampling sliding block is equipped with sampling arc groove, and sampling arc groove is abutted with the surface of positioning slide；
Stirring arc groove is offered on the left of stirring sliding block, stirring arc groove is abutted with the surface of positioning slide.
Wherein, the sampling sliding block offers sampling clip slot, and the sampling tooth band connects through sampling clip slot and sampling sliding block
Connect；The stirring sliding block offers stirring clip slot, and sampling tooth band is connected through stirring clip slot with stirring sliding block；The sampling sliding block
Upper surface offer sampling groove, sample and sampling mounting hole offered in groove, sample in groove and be equiped with sampling latch segment,
The lower end of probe tube from top to bottom sequentially passes through sampling latch segment and sampling mounting hole and is detachably connected with sampling sliding block.
Wherein, the upper surface of the stirring sliding block offers stirring groove, stirs in groove and offers stirring mounting hole, stirs
Mix and stirring latch segment be equiped with groove, the lower end of rabble from top to bottom sequentially pass through stirring latch segment and stirring mounting hole and
Stirring sliding block is detachably connected；The both sides of the sampling substrate are equipped with rib, and rib is vertically arranged with sampling substrate, rib
Surface offers multiple rib through holes.
Wherein, the longitudinal moving mechanism is vertical including arranged in parallel two for being respectively arranged on two pieces of support plate upper ends
Move slide, the vertical shift sliding seat being slidably connected with vertical shift slide rail and the vertical shift driving machine for driving vertical shift sliding seat to slide
Structure；Vertical shift driving mechanism includes being located therein the vertical shift motor and vertical shift driven shaft of one piece of support plate, is respectively arranged on vertical shift motor
Output terminal and vertical shift driven shaft end two vertical shift gears, be engaged in the vertical shift tooth bands of two vertical shift gears, vertical shift tooth
Band is connected with corresponding vertical shift sliding seat；The top of support plate is equipped with two pieces of spacing block sets, and vertical shift slide rail is arranged on two pieces of limit convexes
Between block.
Wherein, the vertical shift sliding seat offers the vertical shift through hole set along the longitudinal direction, and the vertical shift slide rail is sheathed on
In vertical shift through hole, the wear-resisting body of vertical shift is arranged between vertical shift through hole and vertical shift slide rail；The surface of the wear-resisting body of vertical shift offers
Vertical shift limit card slot, is equipped with vertical shift through hole and the matched vertical shift annular protrusion of vertical shift limit card slot；Vertical shift sliding seat is with indulging
L-type contiguous block is equipped between shifting tooth band, the top of L-type contiguous block is connected with vertical shift sliding seat, and the lower part of L-type contiguous block offers
Vertical shift clip slot, vertical shift tooth band are connected through vertical shift clip slot with L-type contiguous block；L-type contiguous block offers at least two locking screws
Hole, is equiped with clamping screw in locking screw pit, the front end face of clamping screw is abutted with the vertical shift tooth band.
Wherein, the transverse moving mechanism includes being arranged between two vertical shift sliding seats transverse slide rail, be installed in wherein
The traversing motor of one vertical shift sliding seat, the traversing driven shaft for being installed in another vertical shift sliding seat, be respectively arranged on traversing electricity
Two traversing gears of the end of the output terminal of machine and traversing driven shaft, be engaged in the traversing tooth band of two traversing gears, can slide
Dynamic traversing sliding seat, the sampling mechanism arranged on transverse slide rail is installed in traversing sliding seat, traversing tooth band and traversing sliding seat
Connection；Traversing sliding seat offers two traversing through holes, and the transverse slide rail is made of two cylinder being arranged in parallel slides, circle
One of vertical shift sliding seat is fixed in one end of column slide, and the other end is fixed on another vertical shift through traversing through hole and slides
Seat.
Wherein, traversing wear-resisting body, the table of traversing wear-resisting body are arranged between the traversing sliding seat and cylinder slide
Face offers traversing limit card slot, be equipped with traversing through hole with the matched traversing annular protrusion of traversing limit card slot, two are vertical
The upper surface for moving sliding seat is connected with fixed plate, and two long sides of fixed plate are folded upward at forming safe edge, and safe edge offers multiple shields
Side through hole.
Wherein, the sample apparatus for placing is included arranged on the sample Storage tray of mounting base and arranged at least one of mounting base
Reaction box, the upper surface of reaction box are equipped with mounting hole and at least two reacting holes, reaction plate are equiped with mounting hole；In mounting base
Equipped with chip inserted plate, chip inserted plate is equipped with chip inserted mouth, and the front end face of mounting base offers corresponding with chip inserted mouth
Jack, be equiped with port lid at the aperture of mounting hole, the upper surface of port lid offers liquid injection hole；The lower surface of port lid is equipped with button
Part, is equipped with the mounting hole and the matched installation card slot of fastener.
Wherein, the mounting base is equipped with the first mounting groove for being used for installing sample Storage tray and for installing reaction box
Two mounting grooves, the bottom of the first mounting groove are equipped with locating part, and the bottom surface of sample Storage tray is spacing recessed equipped with coordinating with locating part
Groove, the two sides of the second mounting groove offer limit sliding chutes, and the two sides of the reaction box are equipped with matched with limit sliding chutes
Chimb；The bottom surface of reaction box is equipped with locking and is recessed, and the bottom of second mounting groove is equipped with locking through hole, locks and is equipped with through hole
Retaining mechanism, retaining mechanism include being arranged at the aperture of locking through hole and with the locking sphere of locking depression cooperation and arranged on lock
Locking spring below tight sphere.
Wherein, the upper surface of the sample Storage tray offers test tube socket, and the bottom of test tube socket is equipped with gasket；Sample
The two sides of Storage tray offer ventilation slot, and ventilation slot is connected through sample Storage tray with the test tube socket；The reaction box
Two sides offer easy to hold the antiskid groove or anti-skid chequer of reaction box.
Wherein, the testing agency includes being arranged on the detection device of the top of the sample apparatus for placing and is put arranged on sample
Put device rear be used for drive the traversing detection driving device of detection device, the lower surface of detection device is equipped with red emission
Device, blue emitter and red blue light detector；Detection driving device includes being arranged at the installation baffle at mounting base rear, arranged on peace
Fill the detection guide rail, the detection sliding seat being slidably connected with detection guide rail and the inspection for driving detection sliding seat to slide of baffle
Driving mechanism is surveyed, detection device is connected with detecting the upper surface of sliding seat；Detection driving mechanism includes the detection electricity being oppositely arranged
Machine and detection driven shaft, be respectively arranged on the output terminal of detection motor and detect two detection gears, engagements of the end of driven shaft
In the detection tooth band that two are detected gear, detection tooth band is connected with the detection sliding seat.
Wherein, the detection sliding seat includes seat body, the front end face arranged on seat body and is slided with the detection guide rail
The detection sliding block of connection, detection device are installed in the upper surface of a body, and the lower part of seat body offers detection clip slot, the inspection
Tooth band is surveyed to be connected with seat body through detection clip slot；The upper and lower surface of detection guide rail offers arc chute, described
The front end face of detection sliding block offers detection groove, and the two sides up and down for detecting groove are equipped with and the matched arc of arc chute
Shape is raised.
Wherein, the detection device is connected with touching display.
Wherein, the fluid path rinse-system includes being arranged at the lower section of sampling mechanism and the container for cleaning sampling mechanism
Tank, the first water pump being connected with the water inlet pipe of container tank, the clear water bottle being connected with the first water pump pipe, the water outlet with container tank
The second water pump, the muddy water bottle being connected with the second water pump pipe and the sampling pump being connected with the upper pipes of probe tube of pipe connection, it is molten
Vessel port is offered at the top of gas tank.
Wherein, which further includes supporting rack, the babinet arranged on supporting rack, arranged on supporting rack
The chamber door in front and the opening and closing driving mechanism between supporting rack and chamber door.
Wherein, the opening and closing driving mechanism includes opposed vertical and is arranged at two of supporting rack both sides support vertical bars, vertical
The folding slide being arranged in support vertical bar, the folding sliding block, the folding sliding block that are slideably positioned in folding slide connect with the chamber door
Connect, be used to drive the folding driving mechanism that folding sliding block slides up and down, folding driving dress wherein being equipped with a support vertical bar
Put including be oppositely arranged up and down two fixing axles, be sheathed on the folding gear of two fixing axles respectively, be engaged in two foldings
The folding tooth band of gear, the folding motor being connected with one of folding gear drive, folding tooth band are connected with folding sliding block.
During the use of the present invention, first sample to be tested and reagent are placed in sample apparatus for placing, then by vertical
To moving mechanism and transverse moving mechanism driving sampling mechanism, sample to be tested is drawn by sampling mechanism and is added to mixing region,
Sampling mechanism is cleaned by fluid path rinse-system, then reagent A is drawn by sampling mechanism and is added to mixing region, fully mixes and treats
Sample and reagent A, while sampling mechanism is cleaned by fluid path rinse-system, then test sample will be treated after mixing by sampling mechanism
Product and reagent A are added in detection zone, and reagent B is added to detection zone again after fluid path rinse-system cleaning sampling mechanism,
Finally by the percentage composition of the glycated protein of the liquid in testing agency's detection detection zone, detection is completed.
The orientation of the present invention is with reference to being subject to attached drawing 1.
The beneficial effects of the present invention are：The present invention drives sampling mechanism by longitudinal moving mechanism and transverse moving mechanism
The addition of reagent and sample is automatically performed, then detects by testing agency the percentage of the glycated protein in sample and reagent automatically and contains
Amount, full name automation mechanized operation, detection efficiency is high, and, the present invention is by sampling mechanism automatic sampling, and sampling precision is high, detection knot
Fruit accuracy is high, and good sampling precision can effectively save reagent cost, avoid the waste of reagent.
Brief description of the drawings
Fig. 1 is the decomposition diagram of the present invention.
Fig. 2 is another decomposition diagram of the present invention.
Fig. 3 is the stereogram of sampling mechanism of the invention, longitudinal moving mechanism and transverse moving mechanism.
Fig. 4 is the decomposition diagram of the sampling mechanism of the present invention.
Fig. 5 is the decomposition diagram of the transverse moving mechanism of the present invention.
Fig. 6 is the decomposition diagram of the longitudinal moving mechanism of the present invention.
Fig. 7 is the sample apparatus for placing and testing agency's stereogram of the present invention.
Fig. 8 is the decomposition diagram of the testing agency of the present invention.
Fig. 9 is the decomposition diagram of the sample apparatus for placing of the present invention.
Figure 10 is the schematic diagram of the fluid path rinse-system of the present invention.
Figure 11 is another schematic diagram of the fluid path rinse-system of the present invention.
Figure 12 is the stereogram of the opening and closing driving mechanism of the present invention.
Reference numeral is：1-support plate, 2-sampling mechanism, 3-longitudinal moving mechanism, 4-transverse moving mechanism, 5-
Base, 6-sample apparatus for placing, 7-testing agency, 8-fluid path rinse-system, 9-sampling substrate, 10-probe tube, 11-
Rabble, 12-sampling motor, 13-sampling tooth band, 14-sampling slide, 15-stirring slide, 16-sampling sliding blocks, 17-
Stir sliding block, 18-positioning slide, 19-sampling arc groove, 20-stirring arc groove, 21-sampling groove, 22-sampling
Latch segment, 23-stirring groove, 24-stirring latch segment, 25-rib, 26-vertical shift slide rail, 27-vertical shift sliding seat, 28-
Vertical shift motor, 29-vertical shift tooth band, 30-spacing block set, the wear-resisting body of 31-vertical shift, 32-vertical shift limit card slot, 33-L-type
Contiguous block, 34-transverse slide rail, 35-traversing motor, 36-traversing tooth band, 37-traversing sliding seat, 38-traversing wear-resistant sleeve
Body, 39-traversing limit card slot, 40-fixed plate, 41-safe edge, 42-mounting base, 43-sample Storage tray, 44-reaction box,
45-mounting hole, 46-reacting hole, 47-reaction plate, 48-chip inserted plate, 49-chip inserted mouth, 50-jack, 51-
Port lid, 52-fastener, the 53-the first mounting groove, the 54-the second mounting groove, 55-locating part, 56-limit sliding chutes, 57-chimb,
58-locking sphere, 59-locking spring, 60-test tube socket, 61-ventilation slot, 62-antiskid groove, 63-detection device,
64-detection driving device, 65-installation baffle, 66-detection guide rail, 67-detection sliding seat, 68-detection motor, 69-inspection
Survey tooth band, 70-seat body, 71-detection sliding block, 72-arc chute, 73-arc convex, 74-touching display, 75-
Container tank, the 76-the first water pump, 77-clear water bottle, the 78-the second water pump, 79-muddy water bottle, 80-locking through hole, 81-sampling
Pump, 82-vessel port, 83-supporting rack, 84-babinet, 85-chamber door, 86-opening and closing driving mechanism, 87-support vertical bar, 88-
Folding slide, 89-folding sliding block, 90-fixing axle, 91-folding tooth band, 92-folding motor.
Embodiment
For the ease of the understanding of those skilled in the art, the present invention is made into one with reference to embodiment and attached drawing 1- Figure 12
The explanation of step, the content that embodiment refers to not are limitation of the invention.
A kind of full-automatic specific protein analyzer, including arranged in parallel two pieces of support plates 1, it is arranged at two pieces of supports
Sampling mechanism 2 between plate 1, arranged on the upper end of two pieces of support plates 1 and for driving what sampling mechanism 2 moved back and forth to vertically move
Mechanism 3, arranged on longitudinal moving mechanism 3 and for driving transverse moving mechanism 4 that sampling mechanism 2 moves left and right, arranged on sampler
The base 5 of the lower section of structure 2, be installed in base 5 upper surface sample apparatus for placing 6, be installed in base 5 and for detecting sample
Testing agency 7 and the fluid path rinse-system 8 for cleaning sampling mechanism 2.
The present invention drives sampling mechanism 2 to be automatically performed reagent and sample by longitudinal moving mechanism 3 and transverse moving mechanism 4
Addition, then detect by testing agency 7 percentage composition of the glycated protein in sample and reagent automatically, full name automation behaviour
To make, detection efficiency is high, and, the present invention is by 2 automatic sampling of sampling mechanism, and sampling precision is high, and testing result accuracy is high, and good
Good sampling precision can effectively save reagent cost, avoid the waste of reagent.
Wherein, the sampling mechanism 2 includes the sampling substrate 9 arranged on the transverse moving mechanism 4, arranged on sampling substrate 9
Probe tube 10 and rabble 11 and the sampling driving mechanism for driving probe tube 10 and rabble 11 to move up and down；Institute
State sampling driving mechanism include being respectively arranged on the sampling motor 12 of sampling substrate 9 top and bottom and sampling driven shaft and
For the sampling tooth band 13 for driving probe tube 10 and rabble 11 to move up and down, sample the output terminal of motor 12 and sample driven shaft
End be connected with sampling gear, sampling tooth band 13 is engaged on sampling gear.Specifically, sampling substrate 9 is installed in the horizontal stroke
To the traversing sliding seat 37 of moving mechanism 4；Sample and be arranged with sampling bearing between the end of driven shaft and sampling gear.By taking
Sample tooth band 13 drives probe tube 10 and rabble 11 completes sampling and stirring work, divides without setting up two bar sampling tooth bands 13 separately
Not Qu Dong probe tube 10 and rabble 11 work, it is simple in structure, beneficial to the Miniaturization Design of protein analyzer, and sample and stirring
Automation mechanized operation, work efficiency are high.
Wherein, sampling mechanism 2 further includes the sampling slide 14 and stirring slide 15 arranged on sampling substrate 9, samples slide 14
Arranged in parallel with stirring slide 15, sampling slide 14 slidably connects sampling sliding block 16, the side of the sampling tooth band 13
It is connected with sampling sliding block 16, the probe tube 10 is installed in sampling sliding block 16, and stirring slide 15 slidably connects stirring sliding block 17,
The opposite side of sampling tooth band 13 is connected with stirring sliding block 17, and the rabble is installed in stirring sliding block 17；Sample slide 14 and stir
Mix and positioning slide 18 is equipped between slide 15, positioning slide 18 is parallel with sampling slide 14, and the right side opening of sampling sliding block 16 is equipped with
Arc groove 19 is sampled, sampling arc groove 19 is abutted with the surface of positioning slide 18；The left side of stirring sliding block 17, which offers, to be stirred
Arc groove 20 is mixed, stirring arc groove 20 is abutted with the surface of positioning slide 18.Sampling sliding block is positioned by positioning slide 18
16, the stability of sampling sliding block 16 is good, will not shake, and passes through positioning slide 18 and positions stirring sliding block 17, stirs sliding block 17
Stability it is good, will not shake.
Wherein, the sampling sliding block 16 offers sampling clip slot, and the sampling tooth band 13 is slided through sampling clip slot and sampling
Block 16 connects；The stirring sliding block 17 offers stirring clip slot, and sampling tooth band 13 is connected through stirring clip slot with stirring sliding block 17；
The upper surface of the sampling sliding block 16 offers sampling groove 21, samples and sampling mounting hole 45 is offered in groove 21, and sampling is recessed
Sampling latch segment 22 is equiped with groove 21, the lower end of probe tube 10 from top to bottom sequentially passes through sampling latch segment 22 and sampling is installed
Hole 45 is detachably connected with sampling sliding block 16.Sampling sliding block 16 and stirring sliding block 17 respectively by sample clip slot and stir clip slot and
Sampling tooth band 13 connects, and connective stability is good；Probe tube 10 is fixedly mounted by sampling latch segment 22, the installation of probe tube 10 is steady
It is qualitative good, it is not easy to loosen, probe tube 10 is detachably connected with sampling sliding block 16, is conveniently replaceable probe tube 10.
Wherein, the upper surface of the stirring sliding block 17 offers stirring groove 23, stirs and stirring peace is offered in groove 23
Hole 45 is filled, stirs and stirring latch segment 24 is equiped with groove 23, the lower end of rabble 11 from top to bottom sequentially passes through stirring locking
Block 24 and stirring mounting hole 45 are detachably connected with stirring sliding block 17；The both sides of the sampling substrate 9 are equipped with rib 25, rib
25 are vertically arranged with sampling substrate 9, and the surface of rib 25 offers multiple 25 through holes of rib.Peace is fixed by stirring latch segment 24
Rabble 11 is filled, the mounting stability of rabble 11 is good, is not easy to loosen, and rabble 11 is detachably connected with stirring sliding block 17, just
In replacement rabble 11.
Wherein, the longitudinal moving mechanism 3 includes being respectively arranged on arranged in parallel two of two pieces of 1 upper ends of support plate
Vertical shift slide rail 26, the vertical shift sliding seat 27 being slidably connected with vertical shift slide rail 26 and slide for driving vertical shift sliding seat 27
Vertical shift driving mechanism；Vertical shift driving mechanism includes being located therein the vertical shift motor 28 and vertical shift driven shaft of one piece of support plate 1, respectively
Arranged on vertical shift motor 28 output terminal and vertical shift driven shaft end two vertical shift gears, be engaged in the vertical of two vertical shift gears
Tooth band 29 is moved, vertical shift tooth band 29 is connected with corresponding vertical shift sliding seat 27；The top of support plate 1 is equipped with two pieces of spacing block sets 30,
Vertical shift slide rail 26 is arranged between two pieces of spacing block sets 30.Specifically, it is arranged between the end of vertical shift driven shaft and vertical shift gear
Vertical shift bearing.Drive vertical shift tooth band 29 to move by vertical shift motor 28, then drive vertical shift sliding seat 27 to move by vertical shift tooth band 29
It is dynamic, so as to fulfill the vertical shift for the horizontal mobile device being installed on vertical shift sliding seat 27, and then 2 vertical shift of sampling mechanism is driven, it is complete
Work into longitudinal sample presentation, the degree of automation is high, and sample presentation is efficient；Power set are used as using vertical shift motor 28, it is vertical easy to control
The stroke of shifting；The movement of vertical shift sliding seat 27 is driven to compare belt with promptness is preferably driven using vertical shift tooth band 29, OK
The control accuracy of journey is high；Spacing block set 30 plays the role of limiting the range of vertical shift sliding seat 27.
Wherein, the vertical shift sliding seat 27 offers the vertical shift through hole set along the longitudinal direction, 26 sets of the vertical shift slide rail
In vertical shift through hole, the wear-resisting body 31 of vertical shift is arranged between vertical shift through hole and vertical shift slide rail 26；The wear-resisting body 31 of vertical shift
Surface offers vertical shift limit card slot 32, is equipped with and the matched vertical shift annular protrusion of vertical shift limit card slot 32 in vertical shift through hole；
L-type contiguous block 33 is equipped between vertical shift sliding seat 27 and vertical shift tooth band 29, top and the vertical shift sliding seat 27 of L-type contiguous block 33 connect
Connect, the lower part of L-type contiguous block 33 offers vertical shift clip slot, and vertical shift tooth band 29 is connected through vertical shift clip slot with L-type contiguous block 33；L
Type contiguous block 33 offers at least two locking screw pits, and clamping screw, the front end of clamping screw are equiped with locking screw pit
Face is abutted with the vertical shift tooth band 29.The setting of the wear-resisting body 31 of vertical shift can be effectively prevented from vertical shift sliding seat 27 and be worn
And damage the dimensional stability of vertical shift sliding seat 27；Using limit card slot and the wear-resisting body 31 of annular protrusion location and installation vertical shift,
The connective stability of the wear-resisting body 31 of vertical shift and vertical shift sliding seat 27 is good, is not easy to loosen；L-type contiguous block 33 is logical with vertical shift tooth band 29
The connection of vertical shift clip slot is crossed, connective stability is good, is not easy to loosen；Vertical shift tooth band 29, vertical shift tooth band 29 and L are locked by clamping screw
The connective stability of type contiguous block 33 is good, is not easy to loosen, and dismounting and change vertical shift tooth band 29 is efficient and convenient.
Wherein, the transverse moving mechanism 4 includes being arranged between two vertical shift sliding seats 27 transverse slide rail 34, be installed in
The traversing motor 35 of one of vertical shift sliding seat 27, the traversing driven shaft for being installed in another vertical shift sliding seat 27, difference
Arranged on traversing motor 35 output terminal and traversing driven shaft end two traversing gears, be engaged in the horizontal strokes of two traversing gears
Moving tooth band 36, be slidably arranged on the traversing sliding seat 37 of transverse slide rail 34, the sampling mechanism 2 is installed in traversing sliding seat 37,
Traversing tooth band 36 is connected with traversing sliding seat 37；Traversing sliding seat 37 offers two traversing through holes, the transverse slide rail 34 by
One of vertical shift sliding seat 27 is fixed in two cylinder slide compositions being arranged in parallel, one end of cylinder slide, and the other end is worn
Cross traversing through hole and be fixed on another vertical shift sliding seat 27.Specifically, it is arranged between the end of traversing driven shaft and traversing gear
There is traversing bearing.Drive traversing tooth band 36 to move by traversing motor 35, then traversing sliding seat 37 is driven by traversing tooth band 36
Mobile, so as to fulfill the traversing completion sample presentation of sampling mechanism 2 on traversing sliding seat 37 is installed in, the degree of automation is high, sample presentation effect
Rate is high；Power set are used as using traversing motor 35, easy to control traversing stroke；Traversing slip is driven using traversing tooth band 36
The movement of seat 37 compares belt with promptness is preferably driven, and the control accuracy of stroke is high；Pass through two circles being arranged in parallel
Column slide positions traversing sliding seat 37, and the positioning accuracy of traversing sliding seat 37 is high.
Wherein, traversing wear-resisting body 38, traversing wear-resisting body are arranged between the traversing sliding seat 37 and cylinder slide
38 surface offers traversing limit card slot 39, is equipped with and the matched traversing convex annular of traversing limit card slot 39 in traversing through hole
To rise, the upper surface of two vertical shift sliding seats 27 is connected with fixed plate 40, and two long sides of fixed plate 40 are folded upward at forming safe edge 41,
Safe edge 41 offers multiple 41 through holes of safe edge.The setting of fixed plate 40 effectively enhance vertical shift sliding seat 27 and cylinder slide it
Between connective stability.
Wherein, the sample apparatus for placing 6 is included arranged on the sample Storage tray 43 of mounting base 42 and arranged on mounting base 42
At least one reaction box 44, the upper surface of reaction box 44 are equipped with 45 and at least two reacting hole 46 of mounting hole, and mounting hole 45 is built-in
Equipped with reaction plate 47；Chip inserted plate 48 is equipped with mounting base 42, chip inserted plate 48 is equipped with chip inserted mouth 49, mounting base 42
Front end face offer jack 50 corresponding with chip inserted mouth 49, port lid 51, port lid 51 are equiped with the aperture of mounting hole 45
Upper surface offer liquid injection hole；The lower surface of port lid 51 is equipped with fastener 52, is equipped with the mounting hole 45 and matches with fastener 52
The installation card slot of conjunction.Sample apparatus for placing 6 is provided with sample Storage tray 43 available for storing samples and reagent and for mixing
The reaction box 44 of sample and reagent, simultaneous reactions box 44 are equipped with for detecting the reaction plate 47 used, can meet sample box at the same time
The demand of the storage of reagent, the mixing of sample and reagent and detection；And reaction box 44 is equipped with least two reacting holes 46, sample
Product the reagent different from two kinds can be mixed in two reacting holes 46 respectively at the same time, be effectively improved protein analyzer
Work efficiency；Specifically, the quantity of the chip inserted mouth 49 is 4.The setting of chip inserted mouth 49 is easy to according to difference
The different chip of detection project grafting so that protein analyzer can detect different detection projects.
Wherein, the mounting base 42 is equipped with the first mounting groove 53 for being used for installing sample Storage tray 43 and is reacted for installing
Second mounting groove 54 of box 44, the bottom of the first mounting groove 53 are equipped with locating part 55, and the bottom surface of sample Storage tray 43 is equipped with and limit
The limiting groove that position part 55 coordinates, the two sides of the second mounting groove 54 offer limit sliding chutes 56, the both sides of the reaction box 44
Face is equipped with chimb 57 matched with limit sliding chutes 56；The bottom surface of reaction box 44 is equipped with locking and is recessed, second mounting groove 54
Bottom be equipped with locking through hole 80, is equipped with retaining mechanism in locking through hole 80, retaining mechanism, which includes being arranged at, locks through hole 80
The locking sphere 58 and the locking spring 59 arranged on 58 lower section of locking sphere coordinated at aperture and with locking depression.Specifically, institute
The quantity for stating the first mounting groove 53 is 1, and the quantity of the second mounting groove 54 is 4.Pass through the first mounting groove 53 and second respectively
54 location and installation sample Storage tray 43 of mounting groove and reaction box 44, accurate positioning are easy for installation；During assembling, reaction box 44 is from
The front of two mounting grooves 54 is slipped into the second mounting groove 54, meanwhile, chimb 57 is inserted into spacing by the front of the second mounting groove 54
In sliding slot 56, the installation of reaction box 44 is completed.The limit installation of reaction box 44, positioning are completed by chimb 57 and limit sliding chutes 56
Accurately, and easy to the dismounting and change of reaction box 44；Reaction box 44 is locked by retaining mechanism, reaction box 44 is difficult to slide, and just
In dismounting
Wherein, the upper surface of the sample Storage tray 43 offers test tube socket 60, and the bottom of test tube socket 60 is equipped with pad
Piece；The two sides of sample Storage tray 43 offer ventilation slot 61, and ventilation slot 61 is through sample Storage tray 43 and the test tube socket
60 connections；The two sides of the reaction box 44 are offered easy to hold the antiskid groove 62 or anti-skid chequer of reaction box 44.In reality
Use during the test tube equipped with sample or reagent can be inserted directly into test tube socket 60 for protein analyzer use；It is logical
The setting of wind groove 61 is easy in test tube insertion sample Storage tray 43；The setting personnel easy to operation of antiskid groove 62 or anti-skid chequer
Reaction box 44 is held, reaction box 44 is pulled out out of second mounting groove 54.
Wherein, the testing agency 7 is included arranged on the detection device 63 of the top of the sample apparatus for placing 6 and arranged on sample
6 rear of product apparatus for placing be used for drive the traversing detection driving device 64 of detection device 63, the lower surface of detection device 63 is set
There are red emitter, blue emitter and red blue light detector；Detection driving device 64 includes being arranged at 42 rear of mounting base
Installation baffle 65, the detection guide rail 66 arranged on installation baffle 65, with detect the detection sliding seat 67 that is slidably connected of guide rail 66 and
For the detection driving mechanism for driving detection sliding seat 67 to slide, detection device 63 is connected with detecting the upper surface of sliding seat 67；
Detection driving mechanism includes the detection motor 68 that is oppositely arranged and detection driven shaft, be respectively arranged on the output terminal that detects motor 68 and
Detect two detection gears of the end of driven shaft, be engaged in the detection tooth band 69 of two detection gears, detection tooth band 69 and institute
Detection sliding seat 67 is stated to connect.Specifically, detect and be arranged with detection bearing between the end of driven shaft and detection gear.In reality
Use during, while multigroup sample to be tested and reagent are added in multiple reaction boxes 44, then by detecting driving device
The top of 64 driving detection devices 63 traversing to each reaction boxes 44 successively, launches equicohesive feux rouges and blue light, while by red
Blue light detector collects the feux rouges reflected and blue light light intensity, red according to formula glycosylated hemoglobin/total hemoglobin=reflection
Light light intensity/reflection blue light light intensity, obtains testing result successively；The present invention can disposably detect the component of multigroup sample to be tested,
Detection efficiency is high.
Wherein, the detection sliding seat 67 includes seat body 70, the front end face arranged on seat body 70 and is led with the detection
The detection sliding block 71 that rail 66 is slidably connected, detection device 63 are installed in the upper surface of a body 70, and the lower part of seat body 70 opens up
There is detection clip slot, the detection tooth band 69 is connected through detection clip slot with seat body 70；Detect upper surface and the following table of guide rail 66
Face offers arc chute 72, and the front end face of the detection sliding block 71 offers detection groove, detects the both sides up and down of groove
Face is equipped with arc convex 73 matched with arc chute 72.By detecting 71 fixed seat body 70 of sliding block, seat can be avoided
Body 70 is directly contacted with detection guide rail 66, is slided for a long time and is worn seat body 70, detection tooth band 69 by detect clip slot with
Seat body 70 connects, and connective stability is good；Specifically, arc convex 73 submerges fastening detection guide rail 66 in arc chute 72,
Being completely embedded property is good between detecting 66 box of guide rail detection sliding block 71.
Wherein, the detection device 63 is connected with touching display 74.During actual use, touch screen displays energy
Enough to show testing result, personnel easy to operation read testing result.
Wherein, the fluid path rinse-system 8 includes being arranged at the lower section of sampling mechanism 2 and for cleaning sampling mechanism 2
Container tank 75, the first water pump 76 being connected with the water inlet pipe of container tank 75, the clear water bottle 77 being connected with 76 pipe of the first water pump, with
Second water pump 78 of the water outlet pipe connection of container tank 75, the muddy water bottle 79 and and probe tube being connected with 78 pipe of the second water pump
The sampling pump 81 of 10 upper pipes connection, offers vessel port 82 at the top of dissolving.In actual use, the first water is started
Clear water in clear water bottle 77 is sent in container tank 75 by pump 76, starts the probe tube that sampling mechanism 2 will be arranged on sampling mechanism 2
10 or rabble 11 through vessel port 82 be sent into container tank 75 in sampled part is cleaned, start the second water pump after the completion of cleaning
Sewage in container tank 75 is detached container tank 75 by 78, completes the cleaning of sampling mechanism 2；The present invention can clean probe tube automatically
10 and rabble 11, cleaning is time-consuming short, is effectively improved the work efficiency of protein analyzer.
Wherein, which further includes supporting rack 83, the babinet 84 arranged on supporting rack 83, arranged on branch
The chamber door 85 in the front of support 83 and the opening and closing driving mechanism 86 between supporting rack 83 and chamber door 85.Driven by folding
Motivation structure 86 automatically controls the folding of chamber door 85, easy to control quick.
Wherein, the opening and closing driving mechanism 86 includes two support vertical bars that opposed vertical is arranged at 83 both sides of supporting rack
87th, the folding slide 88 supported in vertical bar 87, the folding sliding block 89 for being slideably positioned in folding slide 88, folding cunning are vertically arranged at
Block 89 is connected with the chamber door 85, is used to drive the folding that folding sliding block 89 slides up and down wherein being equipped with a support vertical bar 87
Driving device, the folding driving mechanism include be oppositely arranged up and down two fixing axles 90, be sheathed on two fixing axles 90 respectively
Folding gear, the folding tooth band 91 for being engaged in two folding gears, the folding being connected with one of folding gear drive electricity
Machine 92, folding tooth band 91 are connected with folding sliding block 89.In actual use, start folding motor 92 and drive folding tooth band 91
Movement, folding tooth band 91 drives folding sliding block 89 to move upwards, so as to drive chamber door 85 to open up.
Above-described embodiment is the preferable implementation of the present invention, and in addition, the present invention can be realized with other manner,
Do not depart from and any on the premise of present inventive concept obviously replace within protection scope of the present invention.
Claims (8)
- A kind of 1. full-automatic specific protein analyzer, it is characterised in that：Including two pieces of support plates arranged in parallel, it is arranged at Sampling mechanism between two pieces of support plates, arranged on the upper end of two pieces of support plates and the longitudinal direction for driving sampling mechanism to move back and forth Moving mechanism, arranged on longitudinal moving mechanism and for driving transverse moving mechanism that sampling mechanism moves left and right, arranged on sampler Base below structure, be installed in base upper surface sample apparatus for placing, be installed in base and the detection for detecting sample Mechanism and the fluid path rinse-system for cleaning sampling mechanism；The sampling mechanism includes the sampling substrate, the probe tube arranged on sampling substrate and stirring arranged on the transverse moving mechanism Bar and the sampling driving mechanism for driving probe tube and rabble to move up and down；The sampling driving mechanism includes difference Arranged on the sampling motor and sampling driven shaft of the sampling substrate top and bottom and for driving probe tube and rabble The sampling tooth band of lower movement, the end of the output terminal and sampling driven shaft that sample motor are connected with sampling gear, and sampling tooth band is nibbled Close on sampling gear；Sampling mechanism further includes the sampling slide and stirring slide arranged on sampling substrate, and sampling slide and stirring slide are parallel to each other Set, sampling slide slidably connects sampling sliding block, and the side of the sampling tooth band is connected with sampling sliding block, the probe tube dress Arranged on sampling sliding block, stirring slide slidably connects stirring sliding block, and the opposite side for sampling tooth band is connected with stirring sliding block, described to stir Mix bar and be installed in stirring sliding block；Positioning slide is equipped between sampling slide and stirring slide, positioning slide is parallel with sampling slide, The right side opening for sampling sliding block is equipped with sampling arc groove, and sampling arc groove is abutted with the surface of positioning slide；Stir sliding block Left side offers stirring arc groove, and stirring arc groove is abutted with the surface of positioning slide.
- A kind of 2. full-automatic specific protein analyzer according to claim 1, it is characterised in that：The longitudinal moving mechanism It is vertical including being respectively arranged on arranged in parallel two vertical shift slide rail of two pieces of support plate upper ends, being slidably connected with vertical shift slide rail Move sliding seat and the vertical shift driving mechanism for driving vertical shift sliding seat to slide；Vertical shift driving mechanism includes being located therein one The vertical shift motor and vertical shift driven shaft of block support plate, are respectively arranged on the two of the output terminal of vertical shift motor and the end of vertical shift driven shaft A vertical shift gear, the vertical shift tooth band for being engaged in two vertical shift gears, vertical shift tooth band are connected with corresponding vertical shift sliding seat；Support plate Top be equipped with two pieces of spacing block sets, vertical shift slide rail is arranged between two pieces of spacing block sets.
- A kind of 3. full-automatic specific protein analyzer according to claim 2, it is characterised in that：The vertical shift sliding seat is opened Equipped with the vertical shift through hole set along the longitudinal direction, the vertical shift slide rail is sheathed in vertical shift through hole, vertical shift through hole and vertical shift slide rail Between be arranged with the wear-resisting body of vertical shift；The surface of the wear-resisting body of vertical shift offers vertical shift limit card slot, be equipped with vertical shift through hole with The matched vertical shift annular protrusion of vertical shift limit card slot；L-type contiguous block is equipped between vertical shift sliding seat and vertical shift tooth band, L-type connects The top for connecing block is connected with vertical shift sliding seat, and the lower part of L-type contiguous block offers vertical shift clip slot, and vertical shift tooth band passes through vertical shift clip slot It is connected with L-type contiguous block；L-type contiguous block offers at least two locking screw pits, and clamping screw is equiped with locking screw pit, The front end face of clamping screw is abutted with the vertical shift tooth band.
- A kind of 4. full-automatic specific protein analyzer according to claim 2, it is characterised in that：The transverse moving mechanism Including the transverse slide rail between two vertical shift sliding seats, the traversing motor for being installed in one of vertical shift sliding seat, installing Traversing driven shaft in another vertical shift sliding seat, be respectively arranged on the output terminal of traversing motor and the end of traversing driven shaft Two traversing gears, the traversing tooth band for being engaged in two traversing gears, slidably arranged on the traversing sliding seat, described of transverse slide rail Sampling mechanism is installed in traversing sliding seat, and traversing tooth band is connected with traversing sliding seat；Traversing sliding seat offer two it is traversing logical Hole, the transverse slide rail are made of two cylinder being arranged in parallel slides, and one of vertical shift is fixed in one end of cylinder slide Sliding seat, the other end are fixed on another vertical shift sliding seat through traversing through hole.
- A kind of 5. full-automatic specific protein analyzer according to claim 4, it is characterised in that：The traversing sliding seat with Traversing wear-resisting body is arranged between cylinder slide, the surface of traversing wear-resisting body offers traversing limit card slot, traversing through hole Interior be equipped with is connected with fixed plate with the matched traversing annular protrusion of traversing limit card slot, the upper surface of two vertical shift sliding seats, Two long sides of fixed plate are folded upward at forming safe edge, and safe edge offers multiple safe edge through holes.
- A kind of 6. full-automatic specific protein analyzer according to claim 1, it is characterised in that：The sample apparatus for placing Including the sample Storage tray arranged on mounting base and at least one reaction box arranged on mounting base, the upper surface of reaction box is equipped with installation Hole and at least two reacting holes, are equiped with reaction plate in mounting hole；Chip inserted plate is equipped with mounting base, chip inserted plate is equipped with Chip inserted mouth, the front end face of mounting base offer jack corresponding with chip inserted mouth, hole are equiped with the aperture of mounting hole Lid, the upper surface of port lid offers liquid injection hole；The lower surface of port lid is equipped with fastener, is equipped with the mounting hole and is engaged with fastener Installation card slot.
- A kind of 7. full-automatic specific protein analyzer according to claim 6, it is characterised in that：The mounting base, which is equipped with, to be used The first mounting groove in installing sample Storage tray and the second mounting groove for installing reaction box, the bottom of the first mounting groove is equipped with Locating part, the bottom surface of sample Storage tray are equipped with the limiting groove coordinated with locating part, and the two sides of the second mounting groove open up limited Position sliding slot, the two sides of the reaction box are equipped with and the matched chimb of limit sliding chutes；The bottom surface of reaction box is equipped with locking and is recessed, The bottom of second mounting groove is equipped with locking through hole, and retaining mechanism is equipped with locking through hole, and retaining mechanism includes being arranged at lock The locking sphere and the locking spring below locking sphere coordinated at the aperture of tight through hole and with locking depression.
- A kind of 8. full-automatic specific protein analyzer according to claim 1, it is characterised in that：The testing agency includes Arranged on the detection device of the top of the sample apparatus for placing and arranged on sample apparatus for placing rear for driving detection device Traversing detection driving device, the lower surface of detection device are equipped with red emitter, blue emitter and red blue light detector；Inspection Surveying driving device includes being arranged at the installation baffle at mounting base rear, the detection guide rail arranged on installation baffle, is slided with detection guide rail The detection sliding seat of dynamic connection and the detection driving mechanism for driving detection sliding seat to slide, detection device are slided with detection The upper surface connection of seat；Detection driving mechanism includes the detection motor being oppositely arranged and detection driven shaft, is respectively arranged on detection electricity The output terminal of machine and two detection gears of the end of detection driven shaft, the detection tooth band for being engaged in two detection gears, detection Tooth band is connected with the detection sliding seat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610243861.1A CN105866451B (en) | 2016-04-19 | 2016-04-19 | A kind of full-automatic specific protein analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610243861.1A CN105866451B (en) | 2016-04-19 | 2016-04-19 | A kind of full-automatic specific protein analyzer |
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| CN105866451A CN105866451A (en) | 2016-08-17 |
| CN105866451B true CN105866451B (en) | 2018-05-01 |
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| CN201610243861.1A Active CN105866451B (en) | 2016-04-19 | 2016-04-19 | A kind of full-automatic specific protein analyzer |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI657246B (en) * | 2018-04-09 | 2019-04-21 | 冷泉港生物科技股份有限公司 | Automatic liquid injection method and device for detecting single genetic disease |
| CN108931176A (en) * | 2018-07-27 | 2018-12-04 | 潘锐 | A kind of high accuracy depth detection device |
| CN111589489B (en) * | 2020-04-13 | 2021-10-22 | 青岛海尔生物医疗股份有限公司 | Test tube storage system and storage method |
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| US5902548A (en) * | 1996-07-03 | 1999-05-11 | Beckman Instruments, Inc. | Automatic chemistry analyzer |
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| CN104483499A (en) * | 2014-12-30 | 2015-04-01 | 深圳市汇松科技发展有限公司 | Full-automatic particular protein analyzer |
| CN205594017U (en) * | 2016-04-19 | 2016-09-21 | 广东优尼德生物科技有限公司 | Full -automatic specific protein analyzer |
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| JPS5850463A (en) * | 1981-09-19 | 1983-03-24 | Fujitsu General Ltd | Biochemical analyzer |
| US5902548A (en) * | 1996-07-03 | 1999-05-11 | Beckman Instruments, Inc. | Automatic chemistry analyzer |
| CN203502427U (en) * | 2013-09-26 | 2014-03-26 | 北京利德曼生化股份有限公司 | Mechanical arm for sample application |
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| CN105866451A (en) | 2016-08-17 |
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