CN207055568U - A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment - Google Patents
A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment Download PDFInfo
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- CN207055568U CN207055568U CN201720009440.2U CN201720009440U CN207055568U CN 207055568 U CN207055568 U CN 207055568U CN 201720009440 U CN201720009440 U CN 201720009440U CN 207055568 U CN207055568 U CN 207055568U
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Abstract
A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment, solves the problem of being difficult to ensure that probe positions steadiness existing for prior art, couplant thickness evenness is poor, Radiation Center is unstable.Including ultrasonic probe, probe fixing bracket and experiment porch, it is characterised in that:The side of experiment porch sets longitudinal slide rail and longitudinal slide;Elevating mechanism is set on longitudinal slide, connector is set in the middle part of elevating mechanism, lateral adjustment is set on connector;Lateral adjustment front end is provided with the probe fine setting slide of probe fixing bracket, and the bottom of ultrasonic probe sets couplant outer cover, and couplant outer cover is connected with the bottom of probe fine setting slide;The delivery pipe of couplant delivery pump inside couplant outer cover with being connected;The detent of both sides arrangement binding post is provided with the middle part of experiment porch, the opposite side of experiment porch sets fixing card.Its is reasonable in design, compact-sized, and ultrasound wave irradiation central stabilizer, couplant uniform coating thickness, aseptic is good, easy to operate.
Description
Technical field
The utility model belongs to medical experiment apparatus technical field, and in particular to a kind of ultrasound wave irradiation central stabilizer, coupling
Agent uniform coating thickness, aseptic is good, is used for the Experimental Ultrasonic platform of nude mouse tumor animal experiment easily to operate.
Background technology
Current ultrasound wave irradiation experimental animal(Nude mice)The operation of subcutaneous transplantation knurl model, or it is hand-held super by experimenter
Sound instrument pops one's head in complete;Experimental implementation person is difficult to keep probe positions and its stability of detection angle for a long time.Due to
Detection angle is very big to effect of signals, and the signal for easily causing collection gained is all unstable in speed and intensity, it is difficult to sentences
The change of disconnected Transplanted tumor model is due to that experimental animals self reason is also due to caused by probe positions or angle change, because
And reduce the value of monitoring;Experimenter's long-time hand hold transducer can cause finger to ache, deform simultaneously, or even develop into duty
Industry disease.
Also, existing ultrasonic machine generally requires to smear one layer for excluding in operation between probe and experimental animals
The couplant of contact site air, so that the ultrasonic wave that probe is sent can effectively penetrate experimental animals, reach preferable
Detection results.But couplant is required for artificial operation when smearing, i.e. operator squeezes bottled couplant in tested reality
Test on animal body, such operation is comparatively laborious, wastes time and energy, not only adds the working strength of experimenter, but also deposits
Couplant thickness evenness is poor, Radiation Center is unstable, has the deficiency of bacterium etc..Therefore it is necessary the ultrasound to prior art
Experimental provision is improved.
Utility model content
The utility model is aiming above mentioned problem, there is provided a kind of ultrasound wave irradiation central stabilizer, couplant coating layer thickness are equal
Even, aseptic is good, is used for the Experimental Ultrasonic platform of nude mouse tumor animal experiment easily to operate.
Technical scheme is used by the utility model:The Experimental Ultrasonic platform for being used for nude mouse tumor animal experiment includes super
Sonic probe, probe fixing bracket and experiment porch, it is characterised in that:The side of the experiment porch is provided with longitudinal slide rail, longitudinal direction
Longitudinal slide is provided with slide rail, one end of longitudinal slide is provided with longitudinally adjust end;The top of longitudinal slide is provided with vertically
The elevating mechanism of arrangement, connector is provided with the middle part of elevating mechanism, horizontally disposed lateral adjustments machine is provided with connector
Structure;The front end of lateral adjustment is provided with probe fine setting slide, and probe fine setting slide includes slide main body, set in slide main body
The probe chute arranged vertically is equipped with, the sliding end of the probe fixing bracket is arranged on probe chute by fixed knob of popping one's head in
Interior, probe fixed knob is arranged in the knob chute of slide body side;The bare terminal end of probe fixing bracket sets the ultrasound
Probe, the bottom of ultrasonic probe are provided with couplant outer cover, and couplant outer cover is connected with the bottom of probe fine setting slide;Pop one's head in micro-
The top of slide is adjusted to be provided with couplant delivery pump, couplant delivery pump passes through couplant delivery pipe and the inside of couplant outer cover
It is connected;Detent is provided with the middle part of the experiment porch, the both sides of detent are respectively arranged with several binding posts, real
Test on platform, the side relative with longitudinal slide rail is provided with fixing card, one end of fixing card passes through rotary shaft and experiment porch phase
Even, the other end of fixing card is provided with tight locking button.
The elevating mechanism of longitudinal slide Upper vertical arrangement, including the lifting slide bar and lift adjustment spiral shell being parallel to each other
Bar, the lower end for lifting slide bar and lift adjustment screw rod are connected with longitudinal slide, and the upper end for lifting slide bar and lift adjustment screw rod is set
It is equipped with lift adjustment end;Horizontally disposed lateral adjustment on the connector, including the horizontal sliding bar and horizontal stroke being parallel to each other
To adjusting screw rod, the front end of horizontal sliding bar and lateral adjustments screw rod is connected with probe fine setting slide, horizontal sliding bar and lateral adjustments
The rear end of screw rod is provided with lateral adjustments end;The connector set in the middle part of the elevating mechanism includes contiguous block, is set on contiguous block
Be equipped with for respectively with lifting slide bar and the slide bar through hole that is connected of horizontal sliding bar, and for respectively with lift adjustment screw rod and horizontal stroke
The tapped through hole being connected to adjusting screw rod.To finely tune the transverse direction and vertical position of slide to probe, accurate, stable adjust is carried out
It is whole.
The both sides of the experiment porch detent, are respectively arranged with several slotted holes;It is described to be arranged in detent
The binding post of both sides is arranged in slotted hole, and the lower end for bundling post is provided with locking nut.With according to animal experiment body
The position of specific size, neatly regulation binding post, facilitates the fixation of animal experiment body.
Scale is provided with the inwall of the couplant outer cover for being arranged on ultrasonic probe bottom.With to couplant coating
Thickness is marked, and is easy to the regulation of couplant thickness evenness.
The couplant outer cover for being arranged on ultrasonic probe bottom, the connected mode with probe fine setting slide bottom is removable
Formula connects.In order to the cleaning and replacing of couplant outer cover.
The bottom of the experiment porch is provided with four adjustable support legs.In order to the regulation of experiment porch flatness.
The beneficial effects of the utility model:Because the utility model is using the experiment porch of side setting longitudinal slide rail, indulge
Longitudinal slide is set on to slide rail, and longitudinal slide one end sets longitudinally adjust end;Longitudinal slide top sets the liter arranged vertically
Descending mechanism, elevating mechanism middle part set connector, horizontally disposed lateral adjustment are set on connector;Lateral adjustment
Front end is set in the slide main body of probe fine setting slide, sets the probe chute arranged vertically, and the sliding end of probe fixing bracket is set
Put in probe chute;The bottom of the ultrasonic probe of probe fixing bracket bare terminal end sets couplant outer cover, and couplant outer cover is with visiting
The bottom of head fine setting slide is connected;The couplant delivery pump that probe fine setting slide top is set is by couplant delivery pipe with coupling
The inside of agent outer cover is connected;The middle part of experiment porch sets detent, and the both sides of detent set binding post, experiment porch
Upper, relative with longitudinal slide rail side sets the structure type of fixing card, so its is reasonable in design, it is compact-sized, make ultrasonic real
During testing, the distance between ultrasound wave irradiation center and transplantable tumor focusing surface are preferably;Improve traditional-handwork pressurization fixation
Mode of operation, caused couplant uneven thickness, Radiation Center is unstable, has the defects of bacterium;Ultrasound wave irradiation central stabilizer, coupling
Mixture uniform coating thickness, aseptic is good, easy to operate, disclosure satisfy that the requirement of ultrasound wave irradiation in zoopery.
Brief description of the drawings
Fig. 1 is a kind of structural representation of the present utility model.
Fig. 2 is Fig. 1 partial enlarged view.
Fig. 3 is a kind of structural representation of the connector in Fig. 1.
Fig. 4 is a kind of use state partial schematic diagram of the present utility model.
Number explanation in figure:1 couplant outer cover, 2 ultrasonic probes, 3 probe fixing brackets, 4 probe fine setting slides, 5 couplants
Delivery pump, 6 horizontal sliding bars, 7 lateral adjustments screw rods, 8 lift adjustment ends, 9 lifting slide bars, 10 lift adjustment screw rods, 11 are laterally adjusted
Save end, 12 connectors, 13 longitudinal slides, 14 longitudinal slide rails, 15 longitudinally adjust ends, 16 adjustable support legs, 17 experiment porch, 18 positioning
Groove, 19 slotted holes, 20 locking nuts, 21 binding posts, 22 rotary shafts, 23 tight locking buttons, 24 fixing cards, 25 slide main bodys, 26 are visited
Head chute, 27 knob chutes, 28 probe fixed knobs, 29 scales, 30 couplant delivery pipes, 31 contiguous blocks, 32 slide bar through holes, 33
Tapped through hole, 34 couplant coatings, 35 animal experiment bodies.
Embodiment
Concrete structure of the present utility model is described in detail according to Fig. 1~4.The ultrasound that this is used for nude mouse tumor animal experiment is real
The ultrasonic probe 2 that platform includes being used for ultrasound wave irradiation, the probe fixing bracket 3 of fixed ultrasonic probe 2 are tested, and places animal experiment body
Experiment porch 17, wherein, the middle part of experiment porch 17 is provided with the detent 18 for being easy to animal experiment body placement positioning.It is fixed
The both sides of position groove 18, it is provided with four binding posts 21 for being used to fix animal experiment body four limbs;The side of experiment porch 17 is set
The arc fixing card 24 for fixing animal experiment body head is equipped with, one end of arc fixing card 24 passes through rotary shaft 22 and experiment
The upper surface of platform 17 is connected, and the other end of arc fixing card 24 is provided with the tight locking button 23 for the card 24 that is locked.
For the consideration according to the specific size of animal experiment body, neatly regulation binding post 21 position, the detent 18 of experiment porch 17
Both sides set the opening position of binding post 21, are respectively arranged with four slotted holes 19;Four binding posts 21 are separately positioned on slotted hole
In 19, and the lower end for bundling post 21 is provided with the butterfly locking nut 20 for the position of fixation binding post 21, to facilitate animal
The fixation of test body.For the ease of the regulation of the flatness of experiment porch 17, the bottom of experiment porch 17 is provided with four adjustable supportings
Leg 16.
Other side on experiment porch 17, relative with arc fixing card 24, it is provided with for before and after fine setting slide 4 of popping one's head in
The longitudinal slide rail 14 vertically moved, longitudinal slide 13 is provided with longitudinal slide rail 14, one end of longitudinal slide 13, which is provided with, to be used for
The longitudinally adjust end 15 of lengthwise position before and after regulation probe fine setting slide 4.The top of longitudinal slide 13 is provided with what is arranged vertically
Elevating mechanism, elevating mechanism include two lifting slide bars 9 arranged in parallel, lifting are provided between two lifting slide bars 9
Adjusting screw rod 10, lift adjustment screw rod 10 are arranged in parallel with lifting slide bar 9;Lift the lower end of slide bar 9 and lift adjustment screw rod 10
Be connected with the top of longitudinal slide 13, lift slide bar 9 and lift adjustment screw rod 10 upper end be provided with it is micro- for adjusting probe
Adjust the lift adjustment end 8 of the upper-lower height position of slide 4.The connector 12 of L-shaped, lift adjustment spiral shell are provided with the middle part of elevating mechanism
Bar 10 is connected with the vertical tapped through hole 33 on the contiguous block 31 of L-shaped connector 12, and lifting slide bar 9 is connected with L-shaped connector 12
Upright sliding bar through hole 32 on block 31 is connected.Horizontally disposed lateral adjustment is provided with L-shaped connector 12, is laterally adjusted
Section mechanism includes two horizontal sliding bars 6 arranged in parallel, and lateral adjustments screw rod 7 is provided between two horizontal sliding bars 6, horizontal
It is arranged in parallel to adjusting screw rod 7 and horizontal sliding bar 6;The rear end of horizontal sliding bar 6 and lateral adjustments screw rod 7 is provided with to be visited for adjusting
The lateral adjustments end 11 of head fine setting slide 4 or so lateral attitude.The lateral adjustments screw rod 7 of lateral adjustment and L-shaped connector
Horizontal screw thread through hole 33 on 12 contiguous blocks 31 is connected, and horizontal sliding bar 6 is then sliding with the level on the contiguous block 31 of L-shaped connector 12
Rod through-hole 32 is connected.The front end of lateral adjustment horizontal sliding bar 6 and lateral adjustments screw rod 7, and for ultrasonic probe 2
The probe that lower position is finely adjusted is finely tuned slide 4 and is connected, and with accurate, smoothly adjustment probe fine setting slide 4 transverse direction and erects
Straight position.
Probe fine setting slide 4 include slide main body 25, be disposed with vertically in slide main body 25 lifted for ultrasonic probe 2 it is micro-
The probe chute 26 being oriented to is adjusted, the sliding end of probe fixing bracket 3 is arranged in probe chute 26 by fixed knob 28 of popping one's head in, visited
Head fixed knob 28 is arranged in the knob chute 27 of the side of slide main body 25 setting.It is solid that ultrasonic probe 2 is fixedly installed on probe
Determine the bare terminal end of frame 3, the lower outside of ultrasonic probe 2 is arranged with cylindric, the couplant outer cover 1 of upper and lower opening, outside couplant
Cover 1 is connected with the bottom of slide main body 25 of probe fine setting slide 4.For the ease of the cleaning and replacing of couplant outer cover 1, coupling
Agent outer cover 1 and the connected mode of the bottom of 4 slide main body of probe fine setting slide 25 are removable connection.Probe finely tunes the upper of slide 4
Portion is provided with the couplant delivery pump 5 for conveying couplant into couplant outer cover 1, and couplant delivery pump 5 passes through couplant
Delivery pipe 30 is connected with the inside of couplant outer cover 1.According to needs are used, the thickness of couplant is filled in couplant outer cover 1
It can be 5~20mm to spend adjustable range.For the purpose that the thickness of couplant coating 34 is marked, ultrasonic probe 2 is arranged on
Mark scale 29 is provided with the inwall of the couplant outer cover 1 of bottom, in order to the regulation of couplant thickness evenness.
This is used for the Experimental Ultrasonic platform of nude mouse tumor animal experiment when in use, first, by postanesthetic animal experiment body
35(Such as:Nude mice)It is placed in the detent 18 of experiment porch 17, the four limbs of animal experiment body 35 is fixed on binding post
On 21, reuse fixing card 24 and fix the head of animal experiment body 35.Then, ultrasonic probe 2 is fixed on into probe to fix
On frame 3, and couplant outer cover 1 is installed in pop one's head in and finely tunes the bottom of slide 4.According to irradiation zone needed for animal experiment body 35
Physical location, the lift adjustment that longitudinally adjust end 15, the elevating mechanism upper end that longitudinal one end of slide 13 is set are set is adjusted respectively
The lateral adjustments end 11 that end 8 and lateral adjustment rear end are set, couplant of the drive connection in probe fine setting slide 4 bottom
Outer cover 1, the top of the irradiation zone of animal experiment body 35 is moved to, makes lower surface and the animal experiment body 35 of couplant outer cover 1
Body surface is in contact.Fully by the transplantable tumor position of animal experiment body 35 below ultrasonic probe 2, conveniently to irradiate;And
It ensure that the relative stability between ultrasonic probe 2 and animal experiment body 35, it is ensured that experiment is carried out in order.
Start couplant delivery pump 5, couplant is injected by couplant outer cover 1 and animal experiment by couplant delivery pipe 30
In the semiclosed accommodating cavity that the body surface of body 35 is formed, and by the scale 29 on the inwall of couplant outer cover 1, to observe couplant coating
34 thickness;When the thickness of couplant coating 34 reaches thickness needed for ultrasound wave irradiation, couplant delivery pump 5 is closed.Unclamp probe
The probe fixed knob 28 of the side of slide 4 is finely tuned, probe fixing bracket 3 and the ultrasonic probe 2 connected thereon is finely tuned up and down, makes to surpass
The lower end of sonic probe 2 is in contact with the couplant coating 34 in couplant outer cover 1 and is in rational test position;Afterwards, tighten
Probe fixed knob 28.Finally, ultrasonic probe 2 is opened, ultrasound wave irradiation is carried out to the subcutaneous transplantation knurl model of animal experiment body 35, with
Obtain experimental data.So as to alleviate the working strength of experimenter, it is ensured that probe positions and its stability of detection angle,
Avoid hand-held ultrasound probe, grip hand shaking caused by acoustic beam offset error;Stably irradiate transplantable tumor position, lifting prison
Survey the effective value of data.
Claims (6)
1. a kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment, including ultrasonic probe(2), probe fixing bracket(3)And reality
Test platform(17), it is characterised in that:The experiment porch(17)Side be provided with longitudinal slide rail(14), longitudinal slide rail(14)On
It is provided with longitudinal slide(13), longitudinal slide(13)One end be provided with longitudinally adjust end(15);Longitudinal slide(13)Top
The elevating mechanism arranged vertically is provided with, connector is provided with the middle part of elevating mechanism(12), connector(12)On be provided with water
The lateral adjustment that plain cloth is put;The front end of lateral adjustment is provided with probe fine setting slide(4), probe fine setting slide(4)
Including slide main body(25), slide main body(25)On be provided with the probe chute arranged vertically(26), the probe fixing bracket(3)
Sliding end pass through fixed knob of popping one's head in(28)It is arranged on probe chute(26)It is interior, fixed knob of popping one's head in(28)It is arranged in slide master
Body(25)The knob chute of side(27)It is interior;Probe fixing bracket(3)Bare terminal end the ultrasonic probe is set(2), ultrasonic probe
(2)Bottom be provided with couplant outer cover(1), couplant outer cover(1)Slide is finely tuned with probe(4)Bottom be connected;Pop one's head in micro-
Adjust slide(4)Top be provided with couplant delivery pump(5), couplant delivery pump(5)Pass through couplant delivery pipe(30)With coupling
Mixture outer cover(1)Inside be connected;The experiment porch(17)Middle part be provided with detent(18), detent(18)'s
Both sides are respectively arranged with several binding posts(21), experiment porch(17)Upper and longitudinal slide rail(14)Relative side is provided with
Fixing card(24), fixing card(24)One end pass through rotary shaft(22)With experiment porch(17)It is connected, fixing card(24)It is another
End is provided with tight locking button(23).
2. the Experimental Ultrasonic platform according to claim 1 for nude mouse tumor animal experiment, it is characterised in that:The longitudinal direction
Slide(13)The elevating mechanism of Upper vertical arrangement, including the lifting slide bar being parallel to each other(9)With lift adjustment screw rod(10), rise
Slide bar drops(9)With lift adjustment screw rod(10)Lower end and longitudinal slide(13)It is connected, lifts slide bar(9)With lift adjustment screw rod
(10)Upper end be provided with lift adjustment end(8);The connector(12)Upper horizontally disposed lateral adjustment, including it is mutual
Parallel horizontal sliding bar(6)With lateral adjustments screw rod(7), horizontal sliding bar(6)With lateral adjustments screw rod(7)Front end and probe it is micro-
Adjust slide(4)It is connected, horizontal sliding bar(6)With lateral adjustments screw rod(7)Rear end be provided with lateral adjustments end(11);The lifting
The connector set in the middle part of mechanism(12)Including contiguous block(31), contiguous block(31)On be provided with for respectively with lift slide bar
(9)And horizontal sliding bar(6)Connected slide bar through hole(32), and for respectively with lift adjustment screw rod(10)With lateral adjustments spiral shell
Bar(7)Connected tapped through hole(33).
3. the Experimental Ultrasonic platform according to claim 1 for nude mouse tumor animal experiment, it is characterised in that:The experiment
Platform(17)Detent(18)Both sides, be respectively arranged with several slotted holes(19);It is described to be arranged in detent(18)
The binding post of both sides(21)It is arranged on slotted hole(19)It is interior, and bundle post(21)Lower end be provided with locking nut(20).
4. the Experimental Ultrasonic platform according to claim 1 for nude mouse tumor animal experiment, it is characterised in that:The setting
In ultrasonic probe(2)The couplant outer cover of bottom(1)Inwall on be provided with scale(29).
5. the Experimental Ultrasonic platform according to claim 1 for nude mouse tumor animal experiment, it is characterised in that:The setting
In ultrasonic probe(2)The couplant outer cover of bottom(1), slide is finely tuned with probe(4)The connected mode of bottom is removable connection.
6. the Experimental Ultrasonic platform according to claim 1 for nude mouse tumor animal experiment, it is characterised in that:The experiment
Platform(17)Bottom be provided with four adjustable support legs(16).
Priority Applications (1)
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CN201720009440.2U CN207055568U (en) | 2017-01-05 | 2017-01-05 | A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment |
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CN201720009440.2U CN207055568U (en) | 2017-01-05 | 2017-01-05 | A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment |
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CN201720009440.2U Expired - Fee Related CN207055568U (en) | 2017-01-05 | 2017-01-05 | A kind of Experimental Ultrasonic platform for nude mouse tumor animal experiment |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109821161A (en) * | 2019-03-22 | 2019-05-31 | 常州立新医疗美容诊所有限公司 | A kind of medical treatment shaping fat melting equipment |
CN109875602A (en) * | 2019-01-28 | 2019-06-14 | 高密市人民医院 | A kind of auxiliary device for ultrasound diagnosis |
WO2019114046A1 (en) * | 2017-12-13 | 2019-06-20 | 深圳先进技术研究院 | Ultrasonic device and animal fixation device |
CN110169839A (en) * | 2019-05-29 | 2019-08-27 | 上海塔望智能科技有限公司 | A kind of animal spinal cord injury test macro |
CN111759534A (en) * | 2020-07-06 | 2020-10-13 | 温州大学 | Auxiliary device for artificial blood vessel installation |
CN112807125A (en) * | 2021-01-28 | 2021-05-18 | 复旦大学 | Multi-channel small animal ultrasonic stimulation device |
CN113952073A (en) * | 2021-12-08 | 2022-01-21 | 华中科技大学同济医学院附属协和医院 | Mouth gag is fixed to toy tongue for experiments |
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2017
- 2017-01-05 CN CN201720009440.2U patent/CN207055568U/en not_active Expired - Fee Related
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2019114046A1 (en) * | 2017-12-13 | 2019-06-20 | 深圳先进技术研究院 | Ultrasonic device and animal fixation device |
CN109875602A (en) * | 2019-01-28 | 2019-06-14 | 高密市人民医院 | A kind of auxiliary device for ultrasound diagnosis |
CN109875602B (en) * | 2019-01-28 | 2021-10-15 | 王希林 | Auxiliary device for ultrasonic diagnosis |
CN109821161A (en) * | 2019-03-22 | 2019-05-31 | 常州立新医疗美容诊所有限公司 | A kind of medical treatment shaping fat melting equipment |
CN110169839A (en) * | 2019-05-29 | 2019-08-27 | 上海塔望智能科技有限公司 | A kind of animal spinal cord injury test macro |
CN111759534A (en) * | 2020-07-06 | 2020-10-13 | 温州大学 | Auxiliary device for artificial blood vessel installation |
CN111759534B (en) * | 2020-07-06 | 2023-09-26 | 温州大学 | Auxiliary device for artificial blood vessel installation |
CN112807125A (en) * | 2021-01-28 | 2021-05-18 | 复旦大学 | Multi-channel small animal ultrasonic stimulation device |
CN113952073A (en) * | 2021-12-08 | 2022-01-21 | 华中科技大学同济医学院附属协和医院 | Mouth gag is fixed to toy tongue for experiments |
CN113952073B (en) * | 2021-12-08 | 2023-08-15 | 华中科技大学同济医学院附属协和医院 | Small animal tongue fixing mouth gag for experiments |
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CF01 | Termination of patent right due to non-payment of annual fee | ||
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Granted publication date: 20180302 Termination date: 20210105 |