CN206649047U - Automatic enzyme immune luminescence analyzer - Google Patents

Abstract

The utility model discloses automatic enzyme immune luminescence analyzer, including workbench, the upper surface of workbench is provided with suction nozzle carrier, sample carrier, reagent carrier, sample-adding concussion hatching unit, board-washing unit and reading cell, the side of workbench is additionally provided with cross slide way, bearing is slidably fitted with cross slide way, two longitudinal rails are provided with bearing, microplate crawl mechanical arm and sample arm are slidably fitted with longitudinal rail, microplate crawl mechanical arm has the first upright arm vertically lifted and the four-drive device of driving the first upright arm lifting, the bottom of first upright arm is installed with microplate grabbing device, sample arm has the 5th drive device of the second upright arm vertically lifted and driving the second upright arm lifting, sampling sample adding device is installed on sample arm.The beneficial effects of the utility model are：The operation such as sample-adding in enzyme linked immunosorbent detection, board-washing, concussion, incubation, reading and interpretation chromogenic reaction result can be automatically performed, improves operating efficiency, is saved manually, and ensure that test effect.

Description

Automatic enzyme immune luminescence analyzer

Technical field

It the utility model is related to biology and medical test equipment technical field, particularly automatic enzyme immune luminescence analyzer.

Background technology

Enzyme linked immunosorbent detection has been widely used in clinical medicine, moved as a kind of method in many immuno analytical methods The analysis fields such as quality testing epidemic disease, Food Science, plant virus, medicament residue, the prevention and control of plant diseases, pest control.This method has the special of height Property and sensitiveness, the almost all of antibody forming system of soluble antigen one can use it to be detected, its minimum detection value It is horizontal to can reach ng even pg.It is that label is stable and without radiation compared with radiommunoassay, the advantages of enzyme-linked immunoassay Property harm；Compared with immunofluorescence assay, enzyme-linked immunoassay is more objective to result judgement.

Because enzyme-linked immunoassay method needs to use plurality of reagents in the detection, and these reagents are reacted according to experiment Need what is sequentially added, while the micropore for detecting reaction plate must also repeatedly be washed, thus manual operations is relatively complicated.

Utility model content

The shortcomings that the purpose of this utility model is to overcome prior art, there is provided a kind of automaticity is high, it is artificial to save Automatic enzyme immune luminescence analyzer.

The purpose of this utility model is achieved through the following technical solutions：Automatic enzyme immune luminescence analyzer, including work Platform, the upper surface of workbench be provided with suction nozzle carrier, sample carrier, reagent carrier, sample-adding concussion hatching unit, board-washing unit and Reading cell, the side of workbench are additionally provided with cross slide way, bearing are slidably fitted with cross slide way, two are provided with bearing Individual longitudinal rail, longitudinal rail, which is located at a longitudinal direction of the bearing in the side of workbench, described two longitudinal rails, leads Microplate crawl mechanical arm is slidably fitted with rail, sample arm, the side of cross slide way are slidably fitted with another longitudinal rail The driving bearing first driving means that transversely guide rail slides are provided with, it is vertical that driving microplate crawl mechanical arm edge is provided with bearing The 3rd drive device that the second drive device and driving sample arm that direction guiding rail slides are slided along longitudinal rail, microplate crawl machinery Arm has the first upright arm vertically lifted and the four-drive device of driving the first upright arm lifting, the first upright arm Bottom be installed with microplate grabbing device, there is sample arm the second upright arm vertically lifted and driving second to hang down 5th drive device of straight-arm lifting, is provided with sampling sample adding device on sample arm.

In use, transversely guide rail slides bearing, microplate crawl mechanical arm and sample arm slide along respective longitudinal rail, So that microplate crawl mechanical arm and sample arm can do two dimensional motion in portion on the table.Microplate captures the microplate of mechanical arm Grabbing device can realize the migration between sample-adding concussion hatching unit, board-washing unit and reading cell, sample arm by microplate Sampling sample adding device can realize the absorption of blood sample and reagent and the sample-adding successively to each microplate.Specifically, sample arm and taking Blood sample is assigned in microplate hole by sample sample adding device, and sample blood enters sample-adding concussion hatching unit, and incubation, concussion are anti- Should, for example, hepatitis B patient, becomes yellow；Microplate captures mechanical arm and microplate is put into board-washing unit by microplate grabbing device, washes away miscellaneous Matter；After cleaning, microplate is grabbed go back to sample-adding position by microplate crawl mechanical arm and microplate grabbing device；Sample arm and sampling sample-adding dress Put extraction reaction reagent to be loaded, reaction reagent is that enzyme is excused from an examination agent, luminescence reagent etc.；Then board-washing again；Constantly repeat to add After sample board-washing, add termination liquid, microplate is put into reading cell reading, host computer goes out result

Described workbench includes the first framework, and the bottom of the first framework is provided with leg, and the top of framework is provided with platform Face.

Described first driving means include motor and transmission device, and bearing is connected by transmission device and motor Connect, described transmission device is conveyer belt transmission or chain drive or device.

The second described drive device includes motor and transmission device, microplate capture mechanical arm by transmission device with Motor connects, and described transmission device is conveyer belt transmission or chain drive or device.

The 3rd described drive device includes motor and transmission device, and sample arm passes through transmission device and motor Connection, described transmission device is conveyer belt transmission or chain drive or device.

Described four-drive device includes motor, the first drive shaft and the first drive gear, the first drive shaft with Longitudinal rail is parallel, and the first drive gear axially slidably, circumferentially fixedly is installed in the first drive shaft, microplate crawl machinery Arm has a vertical through hole being engaged with the first upright arm, and the first upright arm is slidably mounted in the vertical through hole, and first The sidepiece of upright arm is provided with the tooth being meshed with the first drive gear, and the side of microplate crawl mechanical arm is provided with for housing The groove of first drive gear, the first drive gear are located in the groove and are meshed with the tooth of the first upright arm, microplate crawl The baffle plate being axially limited in the first drive gear in groove is additionally provided with mechanical arm, is provided with baffle plate for the first drive shaft The resigning hole passed through.

The first described drive shaft is polygon by the profile intercepted perpendicular to the section of axis, and the first drive gear is set Have be engaged with the first drive shaft, section be polygon endoporus, endoporus with first driving between centers be gap cooperation.So as to realize There is the first drive shaft to drive the rotation of the first drive gear, while the first drive gear can slide axially along the first drive shaft.

The 5th described drive device includes motor, the second drive shaft and the second drive gear, the second drive shaft with Longitudinal rail is parallel, and the second drive gear axially slidably, circumferentially fixedly is installed in the second drive shaft, and sample arm has one The individual vertical through hole being engaged with the second upright arm, the second upright arm are slidably mounted in the vertical through hole, the second upright arm Sidepiece is provided with the tooth being meshed with the second drive gear, and the side of sample arm is provided with for housing the recessed of the second drive gear Groove, the second drive gear are located in the groove and are meshed with the tooth of the second upright arm, are additionally provided with the on sample arm axially Two drive gears are limited in the baffle plate in groove, and the resigning hole passed through for the second drive shaft is provided with baffle plate.

The second described drive shaft is polygon by the profile intercepted perpendicular to the section of axis, and the second drive gear is set Have be engaged with the second drive shaft, section be polygon endoporus, endoporus with second driving between centers be gap cooperation.So as to realize There is the second drive shaft to drive the rotation of the second drive gear, while the second drive gear can slide axially along the second drive shaft.

Described microplate grabbing device includes the second framework being connected with the first upright arm, and the bottom of the second framework is provided with Horizontal guide rail, the both ends of horizontal guide rail are mounted on a handgrip, and handgrip is slidably mounted on horizontal guide rail, the second framework The handgrip motor of the rotary screw being arranged in vertical and driving rotary screw rotation is internally provided with, rotary screw passes through axle Hold rotation and be installed on horizontal guide rail top, handgrip motor is fixedly installed in the second framework, installed on rotary screw by screw thread There are spiral pieces, two handgrips are connected by a swing arm with spiral pieces respectively, and level is provided perpendicular on spiral pieces The first level bearing pin of guide rail, the sleeve being set in outside rotary screw is fixedly installed on horizontal guide rail, is provided with sleeve First level bearing pin is prevented around rotary screw is circumferentially rotatable, the guide groove that is extends in the vertical direction, first level bearing pin from Stretched out in guide groove, a second horizontal bearing pin parallel to first level bearing pin is provided with each handgrip in axle center, put One end of arm passes through chute and the second horizontal hinge by chute and first level hinge, the other end of swing arm.

In use, handgrip motor forward or reverse, driving rotary screw accordingly rotates, and passes through screw thread and cage guiding groove While act on, spiral pieces vertically move up or down, so as to first level bearing pin pass through swing arm drive second Horizontal bearing pin movement, so that handgrip moves along horizontal slide rail, realizes the merging and separation of two handgrips, so as to realize promptly Microplate and the action for unclamping microplate, realize the automatic loading and unloading of microplate.Specifically, when spiral pieces are at uppermost position in fig-ure, two Individual handgrip is in promptly state；When spiral pieces, which are in lowermost position, puts place, two handgrips are in releasing orientation.

Second horizontal bearing pin of two handgrips is divided into the both sides of spiral pieces, and two first levels are set on spiral pieces Bearing pin, two first level bearing pins are respectively with corresponding second horizontal pin axle position in being provided with two and first on homonymy, sleeve Horizontal bearing pin corresponds the guide groove coordinated.

Described swing arm includes the horizontal arm and upright arm being fixedly connected by swing arm bearing pin, and the end of horizontal arm passes through cunning Groove and first level hinge, the end of upright arm passes through chute and the second horizontal hinge.

The first driven gear is fixedly installed on described rotary screw, is fixedly installed on the motor shaft of handgrip motor One drive gear, the first drive gear are meshed with the second drive gear.

Rubber cushion is provided with described handgrip, has both served the effect of increasing friction force, while forms flexible buffer knot Structure, microplate is played a protective role.

Magnet is provided with least one handgrip in two described handgrips, is provided with and is used on the second described framework Detect the magnetic survey device of magnet.When handgrip is in promptly state, magnet is located at magnetic survey device, so as to handgrip Whether realize and detect in promptly state, it is ensured that promptly in place.

One rotation being extends in the vertical direction fixing axle, fixing axle and second are installed at the top of the second described framework First upright arm is fixedly connected, and rotation fixing axle is installed on the second framework by bearing rotary, is fixedly mounted in the second framework There is electric rotating machine, be fixedly installed the second drive gear on the motor shaft of electric rotating machine, rotate and the is installed with fixing axle Two driven gears, the second drive gear are meshed with the second driven gear.During so as to, electric rotating machine forward or reverse, the is driven Two frameworks carry out the rotation of respective direction around rotation fixing axle, and then realize the horizontal rotation of handgrip to adjust crawl or the side of putting down Position.

Described sampling sample adding device includes support baseboard, and support baseboard is fixedly connected with the second vertical axis, support baseboard On be fixedly installed pin fixed seat, pin fixed seat has gas passage, and the top of pin fixed seat is provided with piston element, and pin is fixed The bottom of seat is installed with draw point, and piston element includes body and the piston rod being arranged in body, and body is fixed by pin The gas passage connection draw point of seat, the end of piston rod are fixedly connected with sliding block, and sliding block is loaded on along Vertical Square by screw thread borehole jack To on the sampling sample-adding screw mandrel of setting, one end rotation of sampling sample-adding screw mandrel is installed on support baseboard, samples the another of sample-adding screw mandrel One end connection sampling sample-adding motor, draw point outer cover are equipped with run-bake-needle fault sleeve, and the end of draw point passes run-bake-needle fault sleeve and is provided with suction Head, sampling probe are installed on the suction nozzle, and a lever is provided with support baseboard, and lever is installed on support by locating shaft rotation On bottom plate, one end of lever is connected on run-bake-needle fault sleeve, and the other end of lever is connected with an activation lever and rotated around locating shaft Support pin motor, support pin motor be arranged on support baseboard, the outer cover of described needle body is equipped with spring, and spring one end is connected to In pin fixed seat, the other end of spring is connected on run-bake-needle fault sleeve.

During sampling, sampling sample-adding motor drives piston rod to move upwards by sampling sample-adding screw mandrel and sliding block, so as to pass through Sampling probe draws reagent；During sample-adding, sampling sample-adding motor drives piston rod to move downward by sampling sample-adding screw mandrel and sliding block, from And reagent is discharged by sampling probe.

When run-bake-needle fault operates, pin motor action is held in the palm, one end of activation lever connection support pin motor is moved upwards, so as to which lever connects The one end for connecing run-bake-needle fault sleeve moves downward, and promotes run-bake-needle fault sleeve to move downward, the sample needle that will be installed by run-bake-needle fault sleeve on suction nozzle Release, complete run-bake-needle fault action, run-bake-needle fault sleeve provides a pulling force by spring all the time；After completing run-bake-needle fault action, support pin motor is reverse Rotation, driving, one end of lever connection support pin motor move downward, so as to which one end of lever connection run-bake-needle fault sleeve is moved upwards, Run-bake-needle fault sleeve moves upwards under the collective effect of spring tension and lever thrust, recovers zero-bit.

Electric machine support is fixedly installed on described support baseboard, support pin motor is installed on electric machine support.

The end set of described run-bake-needle fault sleeve has the first magnet, be provided with support baseboard one be used for detect the first magnetic The suction nozzle detection sensor of body, when device is in zero-bit, the first magnet is located at suction nozzle detection sensor.

One end of described lever connection support pin motor is provided with the second magnet, is provided with support baseboard for detecting the The support pin motor detection sensor of two magnets, when device is in zero-bit, the second magnet is at support pin motor detection sensor.From And when device is in zero-bit, due to suction nozzle detection sensor and support pin motor detection sensor while whether detection means is in Zero-bit, play a part of dual fail-safe, it is zero error to ensure electric machine operation state.

The motor shaft of described support pin motor is connected with screw rod, and the spiral being connected by screw thread with screw rod is set with screw rod Sliding sleeve, the side of spiral sliding sleeve are provided with the axis of guide, the chute for housing the axis of guide are provided with lever, lever passes through chute It is connected with spiral sliding sleeve.The rotation of pin electric motor driven screw is held in the palm, spiral sliding sleeve is connected by the axis of guide, chute attachment structure and lever Connect, so as to limit the rotation of spiral sliding sleeve by lever, so as to which the rotation of screw rod make it that axial direction of the screw sheel along screw rod is two-way flat Move, and then drive one end of lever connection spiral sliding sleeve to be moved upwardly or downwardly.

Preferably, the second described magnet is fixedly installed on spiral slide and put.

Preferably, control panel, suction nozzle detection sensor, support pin motor detection sensor are provided with described support baseboard Electrically connected respectively with control panel with support pin motor.

For depositing the suction nozzle carrier of sampling probe, the sample carrier for depositing sample tube, for depositing reaction reagent Reagent carrier, sample-adding concussion hatching unit, board-washing unit and the reading cell of test tube can use commercially available prod.

Preferably, multiple independences that described sample-adding concussion hatching unit includes carrier guide rail and is arranged on carrier guide rail Mechanism is shaken, carrier guide rail is installed on worktable upper surface, and described independent concussion mechanism includes being fixedly installed on carrier guide rail On mounting bracket, the top of mounting bracket is provided with concussion and is incubated pallet, has concussion to be incubated in pallet and be provided with constant-temperature incubation Device, the bottom that concussion is incubated pallet are connected by multiple elastic gum posts with mounting bracket, and electricity is fixedly installed in mounting bracket The motor that arbor is arranged in vertical, the bottom that concussion is incubated pallet are provided with the orientation axes being arranged in vertical, Eccentric bushing is installed, orientation axes are installed on eccentric bushing by bearing on the motor shaft of motor.

Described constant-temperature incubation device is heat-insulated in concussion incubation pallet including being installed on successively along direction from top to bottom Part and heating plate carrier, the direction of heating plate carrier interior edge from top to bottom are sequentially installed with heating plate, heat-conducting piece and microplate.

Preferably, the microplate Location resilient piece for clamping microplate is provided with described heating plate carrier.

Preferably, described heating plate carrier is incubated pallet with concussion by microplate Location resilient piece and is connected, and concussion is incubated support The side wall of disk is provided with the hanging hole for carry microplate Location resilient piece.

Described board-washing unit includes board-washing flow regulator, and the board-washing flow regulator is arranged in framework, washed Plate flow regulator includes at least two barrels, and each bucket is respectively connected with first magnetic valve, and each first magnetic valve is logical Cross the first port that multiple-pass joint connects the first three-way connection, the second port of the first three-way connection is sequentially connected the by pipeline The water inlet pipe of one regulating valve and pump, the 3rd port of the first three-way connection are sequentially connected the second regulating valve and the second three-way connection First port, the outlet pipe of the second port connection pump of the second three-way connection, the 3rd port of the second three-way connection is sequentially connected Second solenoid valve and cleaning brush.

In use, only opening first magnetic valve, whole device is supplied water by a bucket, second solenoid valve during pump work Open, meanwhile, the Flow-rate adjustment of cleaning brush water outlet is realized by the first regulating valve, the 3rd port of the first three-way connection connects successively The structure of the second regulating valve and the first port of the second three-way connection is connect, forms loop, to realize the protection to pump.

The first described regulating valve is identical with the structure of the second regulating valve, and the first regulating valve and the second regulating valve include valve Body, valve rod, valve element and valve seat, valve body are provided with valve rod installation passage, first medium passage and second medium passage, and described first Medium channel is mutually perpendicular to and connected with second medium passage, and the valve seat is embedded in first medium flow channel, the valve Bar is installed in valve rod installation passage by screw thread, and valve rod stretches into one end connection valve element of valve body, the valve element and valve seat phase Coordinate.First regulating valve and the second regulating valve can be used alone.

The first described regulating valve and the other end of the valve rod of the second regulating valve are respectively connected with what a driving stem rotated Drive device.

Described drive device is the motor axis connection of motor, valve rod and motor.

Preferably, a kind of described board-washing flow regulator includes three buckets, and described multiple-pass joint is four-way connection.

The Flow-rate adjustment of cleaning brush water outlet is realized by the first regulating valve, the protection to pump is realized by the second regulating valve.

Described reading cell includes any one or two kinds in luminous reading plotter and optical filtering reading plotter.

Preferably, described luminous reading plotter includes luminous microplate and is arranged at the reading support plate on luminous microplate top, The plug mounting hole for extending vertically through reading support plate is provided with reading support plate, guide-lighting plug is installed in plug mounting hole, it is guide-lighting Plug is provided with the vertical through hole penetrated for reading fiber unit, and the upper end of the side wall of guide-lighting plug is provided with what is radially extended Annular convex edge, annular convex edge play a part of axial limiting, avoid guide-lighting plug from being dropped out of plug mounting hole, stifled positioned at leaded light The top of head is provided with the fiber fixed frame being fixedly installed on reading support plate, and fiber fixed frame is the cartridge type of under shed, guide-lighting Plug is located inside fiber fixed frame, and compression spring, optical fiber are provided between the top surface of guide-lighting plug top surface and fiber fixed frame The top surface of fixed mount is provided with the resigning hole penetrated for reading fiber unit, and reading fiber unit sequentially passes through resigning hole and compression After spring, the vertical through hole of guide-lighting plug is penetrated, reading fiber unit is fixedly connected with fiber fixed frame, reading fiber unit The luminous reading module connection of other end connection, by luminous reading module process data and obtains result data.

During work, guide-lighting plug is overlaid in the presence of compression spring on luminous microplate, pressure uniformly, stably, so as to The sealing between guide-lighting plug and luminous microplate is ensure that, and then make it that measurement device precision is secure, meanwhile, compression spring is also With the function of implementing correction.

Described luminous microplate, which is fixedly installed on, to be vertically moved on frame, vertically move frame be slidably mounted on it is longitudinally disposed On first level guide rail, driving is additionally provided with first level guide rail and vertically moves frame moves horizontally along first level guide rail the One drive device；First level guide rail is slidably mounted on the second horizontal guide rail transversely set, on the second horizontal guide rail also It is provided with the second drive device that driving first level guide rail moves horizontally along the second horizontal guide rail.

Described first driving means include being divided into first driving wheel and the first driven pulley at first level guide rail both ends, First driving wheel is connected with the first motor, and the first timing belt is arranged between the first driving wheel and the first driven pulley, and longitudinal direction is moved Moving frame is fixedly connected with the first timing belt.

The second described drive device includes being divided into second driving wheel and the second driven pulley at the second horizontal guide rail both ends, Second driving wheel is connected with the second motor, and the second timing belt, the first water are arranged between the second driving wheel and the second driven pulley Level gauge is fixedly connected with the second timing belt.

Guide-lighting plug is overlaid in the presence of compression spring on luminous microplate, and pressure uniformly, stably, is led so as to ensure that Sealing between light plug and luminous microplate, and then make it that measurement device precision is secure；Meanwhile compression spring also has implementation The function of correction；There is provided the translation mechanism that the luminous microplate of driving planar does two dimensional motion, so as to improve detection effect Rate.

Preferably, described optical filtering reading plotter includes bottom plate, and support is installed with bottom plate, and described support includes The front panel and rear board being fixedly connected, mounting groove is formed between front panel and rear board, motor is installed on rear side of rear board, The motor shaft of motor is stretched into mounting groove, and is installed with drive gear on the part that is located in mounting groove of motor shaft, is installed Filter wheel, bearing and contact roller are installed in groove, multiple peaces for being used to install optical filter are circumferentially uniformly laid with filter wheel Hole is filled, optical filter is mounted in each mounting hole, the gear teeth, the gear teeth and driving are provided with the outer circumference surface of the rear side of filter wheel Gear is meshed, and ring-shaped step locating surface is provided with the outer circumference surface of the front side of filter wheel, and bearing and contact roller are covered on On the ring-shaped step locating surface, bearing and drive gear set up separately in the left and right sides of filter wheel bottom and support filter wheel, compress Wheel is arranged at the top of filter wheel and compresses filter wheel.

Optical filtering reading plotter, can only just can be easily by filter wheel by unclamping contact roller by using said structure Take out, so as to when device transports, can individually deposit, overcome easy to be shatter when optical filter together transports with device lack Fall into.Meanwhile support, contact roller are formed to filter wheel from top pair from front and rear sides and the left and right sides using bearing and drive gear Filter wheel, which is formed, to be compressed, and is formed firm location structure, is avoided the dislocation of filter wheel, plant running is reliable and stable.

Described bearing and contact roller is mounted on the leading flank of rear board.

The centre of described filter wheel is provided with phase magnet, and the bottom of mounting groove is provided with for sensing positioning magnetic The close examination zero position switch of iron, the axis for examining zero position switch and filter wheel closely are located in same vertical plane.So as to examine zero position switch closely It can monitor whether filter wheel is in accurate location in real time, when filter wheel misplaces, close examination zero position switch can be examined in time Measure, concurrently send alarm signal to host computer.

Light supply apparatus is installed with the bottom plate of the front side of support, described light supply apparatus includes bulb and fixation The light source passage being arranged on rear side of bulb, is provided with the through hole penetrated for light source passage on front panel, light source passage with positioned at filter The optical filter on halo top is aligned, and optical fiber, optical fiber ligase mark reading module, by enzyme mark reading mould are provided with rear side of support Monochromatic light is incided test solution by block, and realizes photoelectric signal transformation, obtains analytical parameters.

The outer cover of described bulb is equipped with tubular sheath, and the end of tubular sheath is provided with fan.

Optical filtering reading plotter only easily can just be taken out filter wheel by unclamping contact roller, so as to be transported in device It when defeated, can individually deposit, overcome the defects of easily shatter when optical filter together transports with device；Using bearing and sliding tooth Wheel is formed firm from front and rear sides and the left and right sides form support to filter wheel, contact roller is formed to filter wheel from top and compressed Location structure, avoid the dislocation of filter wheel, plant running is reliable and stable.Meanwhile structure of the present utility model is easily changed filter Mating plate, the optical filter of different-waveband is placed on filter wheel itself, when in use, the filter for changing filter wheel can be removed according to demand Mating plate, so as to be convenient for changing the optical filter of different wave length.The utility model uses four point positioning, when needing to remove filter wheel, Breaking contact roller into two with one's hands easily can just take out filter wheel because contact roller be in itself can automatically reset elastic component, inside it Provided with angle spring, automatic pinch roller can be achieved, when needing to break into two with one's hands, be also prone to break into two with one's hands.

Close examination zero position switch can monitor whether filter wheel is in accurate location in real time, when filter wheel misplaces, examine It can in time be detected depending on zero position switch, concurrently send alarm signal to host computer.

The utility model has advantages below：

The utility model can be automatically performed sample-adding, board-washing, concussion, incubation, reading and interpretation in enzyme linked immunosorbent detection and show Colour response result etc. operates, and improves operating efficiency, saves manually, and ensure that test effect.

Brief description of the drawings

Fig. 1 is structural representation of the present utility model.

Fig. 2 is the first upright arm of the present utility model and four-drive device attachment structure schematic diagram.

Fig. 3 is the structural representation of microplate grabbing device of the present utility model.

Fig. 4 is that microplate grabbing device of the present utility model removes the structural representation after the second framework.

Fig. 5 is handgrip and handgrip motor attachment structure schematic diagram

Fig. 6 is the structural representation of sampling sample adding device of the present utility model.

Fig. 7 is the structural representation of the automatic run-bake-needle fault structure of sampling sample adding device.

Fig. 8 is the attachment structure schematic diagram of the lever of sampling sample adding device.

Fig. 9 is the structural representation that sample-adding of the present utility model shakes hatching unit.

Figure 10 is that independent concussion mechanism removes the structural representation that concussion is incubated after pallet.

Figure 11 is the structural representation of board-washing flow regulator.

Figure 12 is the first regulating valve of board-washing flow regulator and the structural representation of the second regulating valve.

Figure 13 is the structural representation of the first regulating valve and the second regulating valve that are connected with drive device.

Figure 14 is the structural representation of luminous reading plotter.

Figure 15 is the reading fiber unit and reading support plate, guide-lighting plug assembling structure schematic diagram of luminous reading plotter.

Figure 16 is the structural representation of optical filtering reading plotter.

Figure 17 is that optical filtering reading plotter unloads the structural representation after front panel and tubular sheath.

In figure, 1- suction nozzle carriers, 2- sample carriers, 3- reagent carriers, 4- sample-adding concussion hatching units, 5- board-washing units, 6- lights reading plotter, 7- cross slide ways, 8- bearings, 9- longitudinal rails, 10- microplates crawl mechanical arm, 11- sample arms, 12- the One drive device, the drive devices of 13- second, 14- teeth, the upright arms of 15- first, 16- four-drive devices, 17- microplates crawl dress Put, the upright arms of 18- second, the drive devices of 19- the 5th, 20- sampling sample adding devices, 21- frameworks, 22- legs, 23- table tops, 24- First drive shaft, the drive gears of 25- first, 26- baffle plates, the drive shafts of 27- second, the frameworks of 28- second, 29- horizontal guide rails, 30- Handgrip, 31- rotary screws, 32- handgrip motors, 33- swing arms, 34- spiral pieces, 35- first level bearing pins, 36- sleeves, 37- Guide groove, the second horizontal bearing pins of 38-, the driven gears of 39- first, the drive gears of 40- first, 41- rubber cushions, 42- magnets, 43- Magnetic survey device, 44- rotation fixing axles, 45- electric rotating machines, the drive gears of 46- second, the driven gears of 47- second, 48- branch Support bottom plate, 49- pin fixed seats, 50- draw points, 51- run-bake-needle fault sleeves, 52- suction nozzles, 53- levers, 54- locating shafts, 55- support pin motors, 56- springs, 57- electric machine supports, the magnets of 58- first, 59- suction nozzle detection sensors, the magnets of 60- second, 61- support pin motor detections Sensor, 62- screw rods, 63- spiral sliding sleeves, the 64- axis of guides, 65- chutes, 66- piston elements, 67- sliding blocks, 68- sampling sample-addings Screw mandrel, 69- sampling sample-adding motors, 70- sampling probes, 71- carrier guide rails, 72- mounting brackets, 73- concussions are incubated pallet, 74- bullets Property glue post, 75- motors, 76- orientation axes, 77- eccentric bushings, 78- bearings, 79- thermal insulation barriers, 80- heating plate carriers, 81- add Backing, 82- heat-conducting pieces, 83- microplates, 84- microplate Location resilient pieces, 85- optical filtering reading plotters, 86- buckets, the magnetic valves of 87- first, 88- multiple-pass joints, the three-way connections of 89- first, the regulating valves of 90- first, 91- pumps, the regulating valves of 92- second, 93- the two or three are connected Head, 94- second solenoid valves, 95- cleaning brush, 96- valve bodies, 97- valve rods, 98- valve elements, 99- valve seats, 100- valve rod installation passages, 101- first medium passages, 102- second medium passages, 103- drive devices, 104- light microplate, 105- reading support plates, 106- Guide-lighting plug, 107- fiber fixed frames, 108- reading fiber units, 109- vertically move frame, 110- first level guide rails, 111- Second horizontal guide rail, the driven pulleys of 112- first, the motors of 113- first, the timing belts of 114- first, the driving wheels of 115- second, The driven pulleys of 116- second, the motors of 117- second, 118- compression springs, 119- bottom plates, 120- front panels, 121- rear boards, 122- mounting grooves, 123- motors, 124- drive gears, 125- filter wheels, 126- bearings, 127- contact rollers, the 128- gear teeth, 129- Ring-shaped step locating surface, 130- phase magnets, 131- close examination zero position switchs, 132- bulbs, 133- light source passages, 134- tubulars shield Set, 135- fans, the luminous reading modules of 136-, 137- enzyme mark reading modules.

Embodiment

The utility model is further described below in conjunction with the accompanying drawings：

As shown in Figure 1 and Figure 2, automatic enzyme immune luminescence analyzer, including workbench, the upper surface of workbench are provided with suction Head carrier 1, sample carrier 2, reagent carrier 3, sample-adding concussion hatching unit 4, board-washing unit 5 and reading cell, the one of workbench Side is additionally provided with cross slide way 7, and bearing 8 is slidably fitted with cross slide way 7, and two longitudinal rails 9 are provided with bearing 8, indulges Direction guiding rail 9 is located at bearing 8 and peace is slided on a longitudinal rail 9 in the side of workbench, described two longitudinal rails 9 Mechanical arm 10 is captured equipped with microplate, sample arm 11 is slidably fitted with another longitudinal rail 9, the side of cross slide way 7 is set There are driving bearing 8 first driving means 12 that transversely guide rail 7 slides, driving microplate crawl mechanical arm 10 is provided with bearing 8 The 3rd drive device that the second drive device 13 and driving sample arm 11 slided along longitudinal rail 9 are slided along longitudinal rail 9, it is micro- Plate crawl mechanical arm 10 has the first upright arm 15 vertically lifted and the 4 wheel driven of driving the first upright arm 15 lifting Dynamic device 16, the bottom of the first upright arm 15 are installed with microplate grabbing device 17, and sample arm 11, which has, vertically to be risen Second upright arm 18 of drop and the 5th drive device 19 of driving the second upright arm 18 lifting, be provided with sample arm 11 sampling plus Sampling device 20.

In use, transversely guide rail 7 slides bearing 8, microplate crawl mechanical arm 10 and sample arm 11 are led along respective longitudinal direction Rail 9 slides, so that microplate crawl mechanical arm 10 and sample arm 11 can do two dimensional motion in portion on the table.Microplate captures The microplate grabbing device 17 of mechanical arm 10 can be realized microplate in sample-adding concussion hatching unit 4, board-washing unit 5 and reading cell Between migration, the sampling sample adding device 20 of sample arm 11 can realize blood sample and reagent absorption and to each microplate successively plus Sample.Specifically, blood sample is assigned in microplate hole by sample arm 11 and sampling sample adding device 20, sample blood enters sample-adding and shaken Hatching unit 4 is swung, is incubated, concussion reaction, for example, hepatitis B patient, becomes yellow；Microplate captures mechanical arm 10 and microplate grabbing device Microplate is put into board-washing unit 5 by 17, washes away impurity；After cleaning, microplate crawl mechanical arm 10 and microplate grabbing device 17 will Microplate grabs go back to sample-adding position；Sample arm 11 and sampling sample adding device 20 extract reaction reagent and are loaded, and reaction reagent is excused from an examination for enzyme Agent, luminescence reagent etc.；Then board-washing again；After constantly repeating sample-adding board-washing, add termination liquid, microplate is put into reading cell reads Number, host computer go out result

Described workbench includes the first framework 21, and the bottom of the first framework 21 is provided with leg 22, the top of framework 21 Table top 23 is installed.

Described first driving means 12 include motor and transmission device, and bearing 8 passes through transmission device and driving electricity Machine connects, and described transmission device is conveyer belt transmission or chain drive or device.

The second described drive device 13 includes motor and transmission device, and microplate captures mechanical arm 10 and filled by being driven Put and be connected with motor, described transmission device is conveyer belt transmission or chain drive or device.

The 3rd described drive device includes motor and transmission device, and sample arm 11 passes through transmission device and driving electricity Machine connects, and described transmission device is conveyer belt transmission or chain drive or device.

Described four-drive device 16 includes motor, the first drive shaft 24 and the first drive gear 25, and first drives Moving axis 24 is parallel with longitudinal rail 9, and the first drive gear 25 is installed on the first drive shaft 24 axially slidable, circumferentially fixedly On, microplate crawl mechanical arm 10 has a vertical through hole being engaged with the first upright arm 15, and the first upright arm 15 slides peace Loaded in the vertical through hole, the sidepiece of the first upright arm 15 is provided with the tooth 14 being meshed with the first drive gear 25, and microplate is grabbed The side of mechanical arm 10 is taken to be provided with groove for housing the first drive gear 25, the first drive gear 25 is located in the groove And be meshed with the tooth 14 of the first upright arm 15, it is additionally provided with microplate crawl mechanical arm 10 and axially limits the first drive gear 25 Baffle plate 26 in groove, the resigning hole passed through for the first drive shaft 24 is provided with baffle plate 26.

The first described drive shaft 24 is polygon by the profile intercepted perpendicular to the section of axis, the first drive gear 25 Be provided be engaged with the first drive shaft 24, section be polygon endoporus, between endoporus and the first drive shaft 24 for gap coordinate. So as to realize that the first drive shaft 24 drives the first drive gear 25 to rotate, while the first drive gear 25 can be along the first drive shaft 24 slide axially.

The 5th described drive device 19 includes motor, the second drive shaft 27 and the second drive gear, the second driving Axle 27 is parallel with longitudinal rail 9, and the second drive gear axially slidably, circumferentially fixedly is installed in the second drive shaft 27, is added Sample arm 11 has a vertical through hole being engaged with the second upright arm 18, and the second upright arm 18 is slidably mounted on the vertical through hole Interior, the sidepiece of the second upright arm 18 is provided with the tooth being meshed with the second drive gear, and the side of sample arm 11, which is provided with, to be used for The groove of accommodating second drive gear, the second drive gear are located in the groove and are meshed with the tooth of the second upright arm 18, added The baffle plate 26 being axially limited in the second drive gear in groove is additionally provided with sample arm 11, is provided with baffle plate 26 and is driven for second The resigning hole that moving axis 27 passes through.

The second described drive shaft 27 is polygon by the profile intercepted perpendicular to the section of axis, and the second drive gear is set Be equipped be engaged with the second drive shaft 27, section be polygon endoporus, between endoporus and the second drive shaft 27 for gap coordinate.From And realize there is the second drive shaft 27 to drive the rotation of the second drive gear, while the second drive gear can be along the second drive shaft 27 axially Slide.

Described microplate grabbing device includes the second framework 28 being connected with the first upright arm, and the bottom of the second framework 28 is set Horizontal guide rail 29 is equipped with, the both ends of horizontal guide rail 29 are mounted on a handgrip 30, and handgrip 30 is slidably mounted on horizontal guide rail On 29, the rotary screw 31 being arranged in vertical that is internally provided with of the second framework 28 is grabbed with what driving rotary screw 31 rotated Torch machine 32, rotary screw 31 are installed on the top of horizontal guide rail 29 by bearing rotary, and handgrip motor 32 is fixedly installed in second In framework 28, spiral pieces 34 are provided with by screw thread on rotary screw 31, two handgrips 30 respectively by a swing arm 33 with Spiral pieces 34 are connected, and the first level bearing pin 35 of horizontal guide rail 29, horizontal guide rail 29 are provided perpendicular on spiral pieces 34 On be fixedly installed the sleeve 36 being set in outside rotary screw 31, be provided with sleeve 36 prevent first level bearing pin 35 around rotation Turn the guide groove 37 that screw rod 31 is circumferentially rotatable, is extends in the vertical direction, first level bearing pin 35 is stretched out of guide groove 37 Go out, a second horizontal bearing pin 38 parallel to first level bearing pin 35 is provided with each handgrip 30 in axle center, swing arm 33 One end is be hinged by chute and first level bearing pin 35, and the other end of swing arm 33 is be hinged by chute and the second horizontal bearing pin 38.

In use, the forward or reverse of handgrip motor 32, driving rotary screw 31 accordingly rotates, and is led by screw thread and sleeve 36 Acted on while to groove 37, spiral pieces 34 vertically move up or down, so as to which first level bearing pin 35 passes through Swing arm 33 drives the second horizontal bearing pin 38 to move, so that handgrip 30 moves along horizontal slide rail, realizes the conjunction of two handgrips 30 And and separation, so as to realize promptly microplate and unclamp the action of microplate, realize the automatic loading and unloading of microplate.Specifically, work as spiral slide When block 34 is at uppermost position in fig-ure, two handgrips 30 are in promptly state；When spiral pieces 34, which are in lowermost position, puts place, two Handgrip 30 is in releasing orientation.

Second horizontal bearing pin 38 of two handgrips 30 is divided into the both sides of spiral pieces 34, and two are set on spiral pieces 34 First level bearing pin 35, two first level bearing pins 35 are located at homonymy with the corresponding second horizontal bearing pin 38 respectively, on sleeve 36 It is provided with two and corresponds the guide groove 37 coordinated with first level bearing pin 35.

Described swing arm 33 includes the horizontal arm and upright arm being fixedly connected by the bearing pin of swing arm 33, and the end of horizontal arm leads to Cross chute to be hinged with first level bearing pin 35, the end of upright arm is be hinged by chute and the second horizontal bearing pin 38.

The first driven gear 39 is fixedly installed on described rotary screw 31, fixes and sets on the motor shaft of handgrip motor 32 The first drive gear 40 is equipped with, the first drive gear 40 is meshed with the second drive gear 46.

Rubber cushion 41 is provided with described handgrip 30, has both served the effect of increasing friction force, while is formed flexible slow Structure is rushed, microplate is played a protective role.

Magnet 42 is provided with two described handgrips 30 at least one handgrip 30, is set on the second described framework 28 It is equipped with the magnetic survey device 43 for detecting magnet 42.When handgrip 30 is in promptly state, magnet 42 is located at magnetic survey At device 43, so as to whether realize detection in promptly state to handgrip 30, it is ensured that promptly in place.

The top of the second described framework 28 is provided with the rotation a being extends in the vertical direction fixing axle 44, fixing axle with The two the first upright arms are fixedly connected, and rotation fixing axle 44 is installed on the second framework 28 by bearing rotary, the second framework 28 Electric rotating machine 45 is inside installed with, the second drive gear 46 is fixedly installed on the motor shaft of electric rotating machine 45, rotation is fixed The second driven gear 47 is installed with axle 44, the second drive gear 46 is meshed with the second driven gear 47.So as to rotation During 45 forward or reverse of motor, the second framework 28 is driven to carry out the rotation of respective direction around rotation fixing axle 44, and then realize and grab The horizontal rotation of hand 30 captures or put down orientation to adjust.

Described sampling sample adding device includes support baseboard 48, and support baseboard 48 is fixedly connected with the second vertical axis, support Pin fixed seat 49 is fixedly installed on bottom plate 48, pin fixed seat 49 has gas passage, and the top of pin fixed seat 49 is provided with work Plunger member 66, the bottom of pin fixed seat 49 are installed with draw point 50, and piston element 66 includes body and is arranged in body Piston rod, body connect draw point 50 by the gas passage of pin fixed seat 49, and the end of piston rod is fixedly connected with sliding block 67, sliding Block 67 is loaded on the sampling being arranged in vertical by screw thread borehole jack and is loaded on screw mandrel 68, sampling sample-adding screw mandrel 68 one end rotation peace Loaded on support baseboard 48, the other end connection sampling sample-adding motor 69 of sampling sample-adding screw mandrel 68, the outer cover of draw point 50 is equipped with de- Needle sleeve 51, the end of draw point 50 pass run-bake-needle fault sleeve 51 and are provided with suction nozzle 52, and sampling probe 70 is installed on the suction nozzle 52, branch One lever 53 is installed, lever 53 is installed on support baseboard 48 by the rotation of locating shaft 54, lever 53 on support bottom plate 48 One end is connected on run-bake-needle fault sleeve 51, and the other end of lever 53 is connected with the support pin that an activation lever 53 rotates around locating shaft 54 Motor 55, support pin motor 55 are arranged on support baseboard 48, and the outer cover of described needle body is equipped with spring 56, and the one end of spring 56 connects It is connected in pin fixed seat 49, the other end of spring 56 is connected on run-bake-needle fault sleeve 51.

During sampling, sampling sample-adding motor 69 drives piston rod to move upwards by sampling sample-adding screw mandrel 68 and sliding block 67, from And reagent is drawn by sampling probe 70；During sample-adding, sampling sample-adding motor 69 drives and lived by sampling sample-adding screw mandrel 68 and sliding block 67 Stopper rod moves downward, so as to discharge reagent by sampling probe 70.

When run-bake-needle fault operates, support pin motor 55 is acted, and one end of the connection support pin of activation lever 53 motor 55 is moved upwards, so as to One end that lever 53 connects run-bake-needle fault sleeve 51 moves downward, and promotes run-bake-needle fault sleeve 51 to move downward, by run-bake-needle fault sleeve 51 by suction nozzle The sample needle installed on 52 is released, and completes run-bake-needle fault action, and run-bake-needle fault sleeve 51 provides a pulling force by spring 56 all the time；Complete run-bake-needle fault After action, support pin motor 55 reversely rotates, and drives, and one end of the connection support pin of lever 53 motor 55 moves downward, so as to lever 53 One end of connection run-bake-needle fault sleeve 51 is moved upwards, run-bake-needle fault sleeve 51 under the collective effect of the pulling force of spring 56 and the thrust of lever 53 to Upper motion, recover zero-bit.

Electric machine support 57 is fixedly installed on described support baseboard 48, support pin motor 55 is installed on electric machine support 57.

The end set of described run-bake-needle fault sleeve 51 has the first magnet 58, and one is provided with support baseboard 48 and is used to detect The suction nozzle detection sensor 59 of first magnet 58, when device is in zero-bit, the first magnet 58 is located at suction nozzle detection sensor 59.

One end of the described connection support pin of lever 53 motor 55 is provided with the second magnet 60, and use is provided with support baseboard 48 In the detection sensor of support pin motor 55 for detecting the second magnet 60, when device is in zero-bit, the second magnet 60 is positioned at support pin motor At 55 detection sensors.So as to when device is in zero-bit, due to suction nozzle detection sensor 59 and ask pin motor 55 to detect sensing Whether detection means is in zero-bit to device simultaneously, plays a part of dual fail-safe, it is zero error to ensure electric machine operation state.

The motor shaft of described support pin motor 55 is connected with screw rod 62, is set with screw rod 62 and is connected by screw thread and screw rod 62 The spiral sliding sleeve 63 connect, the side of spiral sliding sleeve 63 are provided with the axis of guide 64, are provided with lever 53 for housing the axis of guide 64 Chute 65, lever 53 is connected by chute 65 with spiral sliding sleeve 63.The drive screw 62 of support pin motor 55 rotates, spiral sliding sleeve 63 It is connected by the axis of guide 64, the attachment structure of chute 65 with lever 53, so as to limit the rotation of spiral sliding sleeve 63 by lever 53, so as to The rotation of screw rod 62 causes axial two-direction moving of the screw sheel along screw rod 62, and then drives lever 53 to connect spiral sliding sleeve 63 One end is moved upwardly or downwardly.

Preferably, the second described magnet 60 is fixedly installed on spiral sliding sleeve 63.

Preferably, control panel is provided with described support baseboard 48, suction nozzle detection sensor 59, support pin motor 55 detect Sensor and support pin motor 55 electrically connect with control panel respectively.

For depositing the suction nozzle carrier of sampling probe, the sample carrier for depositing sample tube, for depositing reaction reagent Reagent carrier, sample-adding concussion hatching unit, board-washing unit and the reading cell of test tube can use commercially available prod.

Preferably, described sample-adding concussion hatching unit includes carrier guide rail 71 and is arranged at multiple on carrier guide rail 71 Independent concussion mechanism, carrier guide rail 71 are installed on worktable upper surface, and described independent concussion mechanism includes being fixedly installed on load Mounting bracket 72 on frame guide rail 71, the top of mounting bracket 72 are provided with concussion and are incubated pallet 73, have concussion to be incubated pallet 73 Constant-temperature incubation device is inside installed, the bottom that concussion is incubated pallet 73 is connected by multiple elastic gum posts 74 with mounting bracket 72, The motor 75 that motor shaft is arranged in vertical is fixedly installed in mounting bracket 72, the bottom that concussion is incubated pallet 73 is set The orientation axes 76 being arranged in vertical are equipped with, eccentric bushing 77 is installed on the motor shaft of motor 75, orientation axes 76 pass through Bearing 78 is installed on eccentric bushing 77.

Described constant-temperature incubation device include along direction from top to bottom be installed on successively concussion be incubated in pallet 73 every Warmware 79 and heating plate carrier 80, the direction of the interior edge of heating plate carrier 80 from top to bottom are sequentially installed with heating plate 81, heat-conducting piece 82 and microplate 83.

Preferably, the microplate Location resilient piece 84 for clamping microplate 83 is provided with described heating plate carrier 80.

Preferably, described heating plate carrier 80 is incubated pallet 73 with concussion by microplate Location resilient piece 84 and is connected, and shakes The side wall of incubation pallet 73 is provided with the hanging hole for carry microplate Location resilient piece 84.

Described board-washing unit includes board-washing flow regulator, and the board-washing flow regulator is arranged in framework, such as Shown in Figure 11,12,13, board-washing flow regulator includes at least two barrel 86, and each bucket 86 is respectively connected with first electromagnetism Valve 87, each first magnetic valve 87 connect the first port of the first three-way connection 89 by multiple-pass joint 88, and the one or three connects First 89 second port is sequentially connected the water inlet pipe of the first regulating valve 90 and pump 91 by pipeline, and the 3rd of the first three-way connection 89 the Port is sequentially connected the second regulating valve 92 and the first port of the second three-way connection 93, and the second port of the second three-way connection 93 connects The outlet pipe of pump 91 is connect, the 3rd port of the second three-way connection 93 is sequentially connected second solenoid valve 94 and cleaning brush 95.

In use, only opening first magnetic valve 87, supplied water by 86 pairs of whole devices of a bucket, second when pump 91 works Magnetic valve 94 is opened, meanwhile, the Flow-rate adjustment of the water outlet of cleaning brush 95 is realized by the first regulating valve 90, the first three-way connection 89 3rd port is sequentially connected the structure of the second regulating valve 92 and the first port of the second three-way connection 93, forms loop, to realize Protection to pump 91.

The first described regulating valve 90 is identical with the structure of the second regulating valve 92, the first regulating valve 90 and the second regulating valve 92 Include valve body 96, valve rod 97, valve element 98 and valve seat 99, valve body 96 is provided with valve rod installation passage 100, first medium passage 101 and second medium passage 102, the first medium passage 101 is mutually perpendicular to and connected with second medium passage 102, described Valve seat 99 is embedded in first medium flow channel, and the valve rod 97 is installed in valve rod installation passage 100 by screw thread, valve Bar 97 stretches into one end connection valve element 98 of valve body 96, and the valve element 98 is engaged with valve seat 99.First regulating valve 90 and second is adjusted Section valve 92 can be used alone.

The first described regulating valve 90 and the other end of the valve rod 97 of the second regulating valve 92 are respectively connected with a driving stem The drive device 103 of 97 rotations.

Described drive device 103 is the motor axis connection of motor, valve rod 97 and motor.

Preferably, a kind of described board-washing flow regulator includes three buckets 86, and described multiple-pass joint 88 is four-way Joint.

The Flow-rate adjustment of the water outlet of cleaning brush 95 is realized by the first regulating valve 90, is realized by the second regulating valve 92 to pump 91 Protection.

Described reading cell includes any one or two kinds in luminous reading plotter 6 and optical filtering reading plotter 85.

Preferably, as shown in Figure 14,15, described luminous reading plotter 6 includes luminous microplate 104 and is arranged at luminous micro- The reading support plate 105 on the top of plate 104, the plug mounting hole for extending vertically through reading support plate 105 is provided with reading support plate 105, block up Guide-lighting plug 106 is installed in head mounting hole, guide-lighting plug 106 is provided with the vertical through hole penetrated for reading fiber unit 108, The upper end of the side wall of guide-lighting plug 106 is provided with the annular convex edge radially extended, and annular convex edge plays a part of axial limiting, Avoid guide-lighting plug 106 from being dropped out of plug mounting hole, be provided with positioned at the top of guide-lighting plug 106 and be fixedly installed in reading branch Fiber fixed frame 107 on plate 105, fiber fixed frame 107 are the cartridge type of under shed, and guide-lighting plug 106 is located at fiber fixed frame Inside 107, compression spring 118, fiber fixed frame are provided between the top surface of the guide-lighting top surface of plug 106 and fiber fixed frame 107 107 top surface is provided with the resigning hole penetrated for reading fiber unit 108, reading fiber unit 108 sequentially pass through resigning hole and After compression spring 118, the vertical through hole of guide-lighting plug 106 is penetrated, reading fiber unit 108 is fixed with fiber fixed frame 107 to be connected Connect, the luminous reading module 136 of other end connection of reading fiber unit 108 connects, by the luminous processing data of reading module 136 simultaneously Obtain result data.

During work, guide-lighting plug 106 is overlaid in the presence of compression spring 118 on luminous microplate 104, pressure uniformly, It is stable, so as to ensure that the sealing between guide-lighting plug 106 and luminous microplate 104, and then make it that measurement device precision is secure, Meanwhile compression spring 118 also has the function of implementing correction.

Described luminous microplate 104, which is fixedly installed on, to be vertically moved on frame 109, is vertically moved frame 109 and is slidably mounted on edge On longitudinally disposed first level guide rail 110, driving is additionally provided with first level guide rail 110 and vertically moves frame 109 along first The first driving means that horizontal guide rail 110 moves horizontally；First level guide rail 110 is slidably mounted on the second water transversely set On level gauge 111, it is horizontal along the second horizontal guide rail 111 that driving first level guide rail 110 is additionally provided with the second horizontal guide rail 111 The second mobile drive device.

Described first driving means are driven including the first driving wheel and first for being divided into the both ends of first level guide rail 110 Wheel 112, the first driving wheel is connected with the first motor 113, and it is same to be arranged with first between the first driving wheel and the first driven pulley 112 Band 114 is walked, frame 109 is vertically moved and is fixedly connected with the first timing belt 114.

The second described drive device includes being divided into second driving wheel 115 and second at the both ends of the second horizontal guide rail 111 Driven pulley 116, the second driving wheel 115 are connected with the second motor 117, are covered between the second driving wheel 115 and the second driven pulley 116 Provided with the second timing belt, first level guide rail 110 is fixedly connected with the second timing belt.

Guide-lighting plug 106 is overlaid in the presence of compression spring 118 on luminous microplate 104, pressure uniformly, stably, from And the sealing between guide-lighting plug 106 and luminous microplate 104 is ensure that, and then make it that measurement device precision is secure；Meanwhile press Contracting spring 118 also has the function of implementing correction；There is provided the translation machine that the luminous microplate 104 of driving planar does two dimensional motion Structure, so as to improve detection efficiency.

Preferably, as shown in Figure 16,17, described optical filtering reading plotter 85 includes bottom plate 119, and peace is fixed on bottom plate 119 Equipped with support, described support includes the front panel 120 and rear board 121 that are fixedly connected, front panel 120 and rear board 121 it Between form mounting groove 122, the rear side of rear board 121 is provided with motor 123, and the motor shaft of motor 123 is stretched into mounting groove 122, And drive gear 124 is installed with the part that is located in mounting groove 122 of motor shaft, filter wheel is installed in mounting groove 122 125th, bearing 126 and contact roller 127, multiple mounting holes for being used to install optical filter are circumferentially uniformly laid with filter wheel 125, Be mounted on optical filter in each mounting hole, be provided with the gear teeth 128 on the outer circumference surface of the rear side of filter wheel 125, the gear teeth 128 with Drive gear 124 is meshed, and ring-shaped step locating surface 129, bearing 126 are provided with the outer circumference surface of the front side of filter wheel 125 It is covered on the ring-shaped step locating surface 129 with contact roller 127, bearing 126 and drive gear 124 set up separately in filter wheel 125 The left and right sides of bottom simultaneously supports filter wheel 125, and contact roller 127 is arranged at the top of filter wheel 125 and compresses filter wheel 125.

Optical filtering reading plotter 85 by using said structure, can only by unclamp contact roller 127 just can easily by Filter wheel 125 takes out, so as to when device transports, can individually deposit, it is easy when optical filter together transports with device to overcome The defects of shatter.Meanwhile branch is formed to filter wheel 125 from front and rear sides and the left and right sides using bearing 126 and drive gear 124 Support, contact roller 127 are formed to filter wheel 125 from top and compressed, and are formed firm location structure, are avoided the dislocation of filter wheel 125, Plant running is reliable and stable.

Described bearing 126 and contact roller 127 is mounted on the leading flank of rear board 121.

The centre of described filter wheel 125 is provided with phase magnet 130, and the bottom of mounting groove 122, which is provided with, to be used for Sense the close examination zero position switch 131 of phase magnet 130, close examination zero position switch 131 is with the axis of filter wheel 125 positioned at same vertical In face.So as to which close examination zero position switch 131 can monitor whether filter wheel 125 is in accurate location in real time, when filter wheel 125 is sent out During raw dislocation, close examination zero position switch 131 can detect in time, concurrently send alarm signal to host computer.

Light supply apparatus is installed with the bottom plate 119 of the front side of support, described light supply apparatus includes bulb 132 With the light source passage 133 for being fixedly installed on the rear side of bulb 132, be provided with front panel 120 penetrated for light source passage 133 it is logical Hole, light source passage 133 align with the optical filter positioned at the top of filter wheel 125, optical fiber are provided with rear side of support and (is not shown in figure Go out), optical fiber ligase mark reading module 137, monochromatic light is incided into test solution by enzyme mark reading module 137, and realize photoelectricity Signal is changed, and obtains analytical parameters.

The outer cover of described bulb 132 is equipped with tubular sheath 134, and the end of tubular sheath 134 is provided with fan 135.

Optical filtering reading plotter 85 only easily can just be taken out filter wheel 125 by unclamping contact roller 127, so as to When device transports, it can individually deposit, overcome the defects of easily shatter when optical filter together transports with device；Using bearing 126 and drive gear 124 support, contact roller 127 are formed to filter wheel 125 from front and rear sides and the left and right sides from top to filtering Wheel 125, which is formed, to be compressed, and is formed firm location structure, is avoided the dislocation of filter wheel 125, plant running is reliable and stable.Meanwhile this The structure of utility model is easily changed optical filter, and the optical filter of different-waveband is placed on filter wheel 125 itself, when in use, can To remove the optical filter for changing filter wheel 125 according to demand, so as to be convenient for changing the optical filter of different wave length.The utility model is adopted With four point positioning, when needing to remove filter wheel 125, breaking contact roller 127 into two with one's hands easily can just take out filter wheel 125, because For contact roller 127 be in itself can automatically reset elastic component, be internally provided with angle spring, can be achieved automatic pinch roller, needing When breaking into two with one's hands, it is also prone to break into two with one's hands.

Close examination zero position switch 131 can monitor whether filter wheel 125 is in accurate location in real time, when filter wheel 125 occurs During dislocation, close examination zero position switch 131 can detect in time, concurrently send alarm signal to host computer.

Claims (10)

1. automatic enzyme immune luminescence analyzer, it is characterised in that：Including workbench, the upper surface of workbench is provided with suction nozzle carrier (1), sample carrier (2), reagent carrier (3), sample-adding concussion hatching unit (4), board-washing unit (5) and reading cell, workbench Side be additionally provided with cross slide way (7), bearing (8) is slidably fitted with cross slide way (7), bearing is provided with two on (8) Longitudinal rail (9), longitudinal rail (9) are located at bearing (8) in the side of workbench, described two longitudinal rails (9) Microplate crawl mechanical arm (10) is slidably fitted with one longitudinal rail (9), is slidably fitted with and adds on another longitudinal rail (9) Sample arm (11),

The side of cross slide way (7) is provided with driving bearing (8) first driving means (12) that transversely guide rail (7) slides,

The second drive device (13) that driving microplate crawl mechanical arm (10) slides along longitudinal rail (9) is provided with bearing (8) The 3rd drive device slided with driving sample arm (11) along longitudinal rail (9),

Microplate crawl mechanical arm (10) has the first upright arm (15) and the first upright arm of driving (15) vertically lifted The four-drive device (16) of lifting, the bottom of the first upright arm (15) are installed with microplate grabbing device (17),

Sample arm (11) has the second upright arm (18) for vertically lifting and the second upright arm of driving (18) lifts the Five drive devices (19), sampling sample adding device (20) is installed on sample arm (11).

2. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：Described workbench includes first Framework (21), the bottom of the first framework (21) are provided with leg (22), and the top of framework (21) is provided with table top (23).

3. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：Described four-drive device (16) motor, the first drive shaft (24) and the first drive gear (25), the first drive shaft (24) and longitudinal rail (9) are included Parallel, the first drive gear (25) is installed in the first drive shaft (24) axially slidable, circumferentially fixedly, microplate crawl machinery Arm (10) has a vertical through hole being engaged with the first upright arm (15), and it is vertical that the first upright arm (15) is slidably mounted on this In through hole, the sidepiece of the first upright arm (15) is provided with the tooth (14) being meshed with the first drive gear (25), microplate gripper The side of tool arm (10) is provided with the groove for housing the first drive gear (25), and the first drive gear (25) is located at the groove Interior and with the first upright arm (15) tooth (14) is meshed, and is additionally provided with the first driving on microplate crawl mechanical arm (10) axially Gear (25) is limited in the baffle plate (26) in groove, and the resigning hole passed through for the first drive shaft (24) is provided with baffle plate (26).

4. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：The 5th described drive device (19) motor, the second drive shaft (27) and the second drive gear are included, the second drive shaft (27) is flat with longitudinal rail (9) OK, the second drive gear axially slidably, circumferentially fixedly is installed in the second drive shaft (27), and sample arm (11) has one The vertical through hole being engaged with the second upright arm (18), the second upright arm (18) are slidably mounted in the vertical through hole, and second hangs down The sidepiece of straight-arm (18) is provided with the tooth being meshed with the second drive gear, and the side of sample arm (11) is provided with for housing the The groove of two drive gears, the second drive gear are located in the groove and are meshed with the tooth of the second upright arm (18), sample arm (11) be additionally provided with the baffle plate (26) axially the second drive gear being limited in groove on, baffle plate is provided with for second on (26) The resigning hole that drive shaft (27) passes through.

5. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：Described microplate grabbing device bag The second framework (28) being connected with the first upright arm is included, the bottom of the second framework (28) is provided with horizontal guide rail (29), and level is led The both ends of rail (29) are mounted on a handgrip (30), and handgrip (30) is slidably mounted on horizontal guide rail (29), the second framework (28) the handgrip motor for being internally provided with the rotary screw (31) being arranged in vertical and driving rotary screw (31) rotation (32), rotary screw (31) is installed on horizontal guide rail (29) top by bearing rotary, and handgrip motor (32) is fixedly installed in In two frameworks (28), spiral pieces (34) are provided with by screw thread on rotary screw (31), two handgrips (30) pass through one respectively Individual swing arm (33) is connected with spiral pieces (34), and the first level of horizontal guide rail (29) is provided perpendicular on spiral pieces (34) Bearing pin (35), it is fixedly installed on horizontal guide rail (29) and is set in the outside sleeve (36) of rotary screw (31), on sleeve (36) It is provided with and prevents first level bearing pin (35) around rotary screw (31) is circumferentially rotatable, the guide groove that is extends in the vertical direction (37), first level bearing pin (35) is stretched out out of guide groove (37), be provided with each handgrip in axle center (30) one it is parallel In the second horizontal bearing pin (38) of first level bearing pin (35), one end of swing arm (33) passes through chute and first level bearing pin (35) Be hinged, the other end of swing arm (33) is be hinged by chute and the second horizontal bearing pin (38).

6. automatic enzyme immune luminescence analyzer according to claim 5, it is characterised in that：On described rotary screw (31) The first driven gear (39) is fixedly installed, the first drive gear (40) is fixedly installed on the motor shaft of handgrip motor (32), First drive gear (40) is meshed with the second drive gear (46).

7. automatic enzyme immune luminescence analyzer according to claim 5, it is characterised in that：Described the second framework (28) Top is provided with the rotation a being extends in the vertical direction fixing axle (44), and fixing axle is fixedly connected with the two the first upright arms, Rotation fixing axle (44) is installed on the second framework (28) by bearing rotary, and electric rotating is installed with the second framework (28) Machine (45), is fixedly installed the second drive gear (46) on the motor shaft of electric rotating machine (45), fixed in rotation fixing axle (44) Second driven gear (47) is installed, the second drive gear (46) is meshed with the second driven gear (47).

8. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：Described sampling sample adding device bag Support baseboard (48) is included, support baseboard (48) is fixedly connected with the second vertical axis, and being fixedly installed pin on support baseboard (48) consolidates Reservation (49), pin fixed seat (49) have gas passage, and the top of pin fixed seat (49) is provided with piston element (66), and pin is fixed The bottom of seat (49) is installed with draw point (50), and piston element (66) includes body and the piston rod being arranged in body, pipe Body connects draw point (50) by the gas passage of pin fixed seat (49), and the end of piston rod is fixedly connected with sliding block (67), sliding block (67) it is loaded on the sampling being arranged in vertical by screw thread borehole jack to be loaded on screw mandrel (68), screw mandrel (68) one end rotation of sampling sample-adding Turn to be installed on support baseboard (48), the other end connection sampling sample-adding motor (69) of sampling sample-adding screw mandrel (68), draw point (50) Outer cover is equipped with run-bake-needle fault sleeve (51), and the end of draw point (50) passes run-bake-needle fault sleeve (51) and is provided with suction nozzle (52), sampling probe (70) it is installed on the suction nozzle (52), a lever (53) is installed on support baseboard (48), lever (53) passes through locating shaft (54) rotation be installed on support baseboard (48), one end of lever (53) is connected on run-bake-needle fault sleeve (51), lever (53) it is another One end is connected with the support pin motor (55) that an activation lever (53) rotates around locating shaft (54), and support pin motor (55) is arranged at branch Supportting on bottom plate (48), the outer cover of described draw point is equipped with spring (56), and spring (56) one end is connected in pin fixed seat (49), The other end of spring (56) is connected on run-bake-needle fault sleeve (51).

9. automatic enzyme immune luminescence analyzer according to claim 8, it is characterised in that：Described support pin motor (55) Motor shaft is connected with screw rod (62), and the spiral sliding sleeve (63) being connected by screw thread with screw rod (62), spiral shell are set with screw rod (62) The side of rotation sliding sleeve (63) is provided with the axis of guide (64), and the chute for housing the axis of guide (64) is provided with lever (53) (65), lever (53) is connected by chute (65) with spiral sliding sleeve (63), support pin motor (55) drive screw (62) rotation, spiral Sliding sleeve (63) is connected by the axis of guide (64), chute (65) attachment structure with lever (53).

10. automatic enzyme immune luminescence analyzer according to claim 1, it is characterised in that：Described sample-adding concussion hatching Unit includes carrier guide rail (71) and the multiple independent concussion mechanisms being arranged on carrier guide rail (71), carrier guide rail (71) installation In worktable upper surface, described independent concussion mechanism includes the mounting bracket (72) being fixedly installed on carrier guide rail (71), The top of mounting bracket (72) is provided with concussion and is incubated pallet (73), has concussion to be incubated in pallet (73) and is provided with constant-temperature incubation dress Put, the bottom that concussion is incubated pallet (73) is connected by multiple elastic gum posts (74) with mounting bracket (72), mounting bracket (72) On be fixedly installed the motor (75) that motor shaft is arranged in vertical, the bottom that concussion is incubated pallet (73) is provided with edge The orientation axes (76) that vertical direction is set, eccentric bushing (77) is provided with the motor shaft of motor (75), and orientation axes (76) are logical Bearing (78) is crossed to be installed on eccentric bushing (77).