CN108761109A - Sampling device and detection analysis instrument with the device - Google Patents

Sampling device and detection analysis instrument with the device Download PDF

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Publication number
CN108761109A
CN108761109A CN201810796055.6A CN201810796055A CN108761109A CN 108761109 A CN108761109 A CN 108761109A CN 201810796055 A CN201810796055 A CN 201810796055A CN 108761109 A CN108761109 A CN 108761109A
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CN
China
Prior art keywords
sample
mobile platform
sampling device
trigger
positioning component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810796055.6A
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Chinese (zh)
Inventor
邹继华
朱磊
徐磊
陈宇迪
徐勇
冯喆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangxi Wei Shui Biotechnology Co Ltd
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Jiangxi Wei Shui Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangxi Wei Shui Biotechnology Co Ltd filed Critical Jiangxi Wei Shui Biotechnology Co Ltd
Priority to CN201810796055.6A priority Critical patent/CN108761109A/en
Publication of CN108761109A publication Critical patent/CN108761109A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742Type of codes
    • G01N2035/00752Type of codes bar codes

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention provides a kind of sampling device, including support baseboard, setting guide rail and the mobile platform for carrying sample on support baseboard;Drive component, multiposition positioning component, sample reading assembly;Wherein drive component driving mobile platform is moved along guide rail, and multiposition positioning component is for determining that mobile platform is positioned at desired location, and sample reading assembly is for judging whether there is sample and reading sample information.The present invention drives mobile platform to be moved along guide rail by the way that drive component is arranged, sampler sampling can be located in sample position automatically by coordinating multiposition positioning component and sample reading assembly to realize sampling device simultaneously, terminal with compact integral structure reliability is high, easy to operate, and sampling device operates steadily.

Description

Sampling device and detection analysis instrument with the device
Technical field
The present invention relates to technical field of medical equipment, and in particular to a kind of inspection detection device, more particularly, to one kind point Analyse detection sampling device.
Background technology
The detection of piarhemia parting is for the cholesterol level for measuring all kinds of lipoprotein.It is different according to the density of lipoprotein, it can be with Lipoprotein is divided into chylomicron (CM), very low density lipoprotein (VLDL), intermediated-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in vain.Current clinically conventional determining not only has total cholesterol (T-CH), also LDL- C, HDL-C.Wherein the too high levels of LDL-C are easy to cause atherosclerosis, and HDL-C there is certain protection to make blood vessel With.But it has recently been demonstrated that either LDL-C or HDL-C all have heterogeneity, clinical meaning is also not exactly the same. As LDL-C is segmented into many subfractions, sdLDL-C (sdLDL-C), since its structure more causes It is close, it is more prone to cause atherosclerosis, also referred to as Type B, and big and light low density lipoprotein cholesterol (LLDL-C) then phase The ability of atharosclerosis is weaker than under, also known as A types.In HDL-C, it can also at least be divided into two kinds of main subgroups Point, such as big and light HDL2 particles and small and dense HDL3 particles, some research evidences have shown that the subgroup for measuring HDL The risk of angiocardiopathy can preferably be reacted than only measuring HDL by dividing.The sampling device of traditional analysis detecting instrument mostly uses Disc rotation movement mode, volume shared by device is big, and using when need that manually centrifuge tube is fixed in sample rack, it is fixed After be placed on designated position, then sample rack to designated position is gripped by coordinate mechanical arm and is sampled, inconvenient, detection efficiency is very It is low.
Invention content
In order to solve the above technical problems, the present invention provides a kind of easy to operate, the detecting system sample introduction that occupies little space dress It sets.
The technical solution of the present invention is to provide a kind of sampling device, including support baseboard, on support baseboard setting guide rail and Carry the mobile platform of sample;Drive component, multiposition positioning component, sample reading assembly;Wherein drive component driving movement Platform is moved along guide rail, and for determining that mobile platform is positioned at desired location, sample reading assembly is used for multiposition positioning component It judges whether there is sample and reads sample information;
Further include resetting probe unit to be used to judge whether to send out the instruction that mobile platform is mobile or resets, resets detection Unit can be fixed on support baseboard, can also be fixed on other positions of detection analysis instrument.
Further, it includes initial position probe unit and final position probe unit to reset probe unit, is respectively set At the original position of mobile platform movement and final position.
Further, further include sample rack, sample rack can be fixed on mobile platform or detachably connect with mobile platform It connects;Preferably sample rack is detachably connected with mobile platform.
Further, drive component includes driving motor, synchronous belt, synchronizing wheel and the driving company being connect with mobile platform Fitting, to realize that mobile platform moves.
Further, multiposition positioning component includes that sample reads positioning component and just last position positioning component, and sample is read Mobile platform is positioned at sample information reading, sample position by positioning component, and sample reading assembly will determine that in this position at this time With the presence or absence of sample, while sample information can also be read;Just end position positioning component by mobile platform be positioned at initial position and End position eventually.
Further, sample read positioning component positioning position be sample information reading position and sample position, it is each Position includes mutually matched signalling means and trigger.
Further, signalling means is optocoupler or optoelectronic switch, and trigger is chopper blade, and wherein chopper blade is dentation chopping the light Piece.
Further, multiposition positioning component is set to mobile platform bottom surface, i.e. multiposition positioning component installation space is Between mobile platform and support baseboard, sampling device volume is reduced to the greatest extent, save detection analysis instrument space.
The advantages of the present invention:The present invention drives mobile platform to be moved along guide rail by the way that drive component is arranged, Coordinating multiposition positioning component and sample reading assembly to realize sampling device simultaneously can be located in sample position automatically Sampler samples, and terminal with compact integral structure reliability is high, easy to operate, and sampling device operates steadily.
Description of the drawings
Fig. 1 is the schematic elevation view of sampling device of the present invention.
Fig. 2 is the schematic top plan view of sampling device of the present invention.
Fig. 3 is the schematic side view of sampling device of the present invention.
Fig. 4 is the partial structural diagram of sampling device of the present invention.
Fig. 5 is the schematic diagram at another visual angle of Fig. 4 structures.
Fig. 6 is the schematic diagram at the another visual angle of Fig. 4 structures.
Fig. 7 is the structural schematic diagram of the second trigger in Fig. 4.
Fig. 8 is the structural schematic diagram of the first trigger in Fig. 4.
Reference numeral:1- support baseboards, 2- drive components, 21- synchronizing wheels, 22- synchronous belts, 23- stepper motors, 24- drive Follower link, 3- multiposition positioning components, 31- samples reading positioning component, the first signalling means of 311-, the first triggers of 312-, 313- second signal devices, the second triggers of 314-, 314a- teeth lack, 314b- teeth, the first last position positioning components of 32-, 321- initial bits Signalling means, the whole last position signalling means of 322-, 4- sample reading assemblies, 41- sample identification units, 42- sample information reading units, 43- linking arms, 5- guide rails, 51- sliding blocks, 6- mobile platforms, 61- sample racks, 62- samples, 7- reset probe unit, 71- startings Position detection unit, 72- final position probe units
Specific implementation mode
The invention will be further described With reference to embodiment.
The present invention provides a kind of sampling device, as shown in Figures 1 to 3, including support baseboard 1, guide rail is arranged on support baseboard 1 5 and carrying sample mobile platform 6;Drive component 2, multiposition positioning component 3, sample reading assembly 4;Wherein drive component 2 Driving mobile platform 6 is moved along guide rail 5, and multiposition positioning component 3 is for determining that mobile platform 6 is positioned at desired location, sample Reading assembly 3 is for judging whether there is sample and reading sample information;Drive component 2, multiposition positioning component 3, sample are read It takes component 4 that can be set on support baseboard, other positions of detection analysis instrument can also be set to.
Further include the instruction for resetting probe unit 7 and being used to judge whether to send out the movement of mobile platform 6 or resetting, resets and visit Surveying unit 7 can be fixed on support baseboard 1, can also be fixed on other positions of detection analysis instrument.
In further improved embodiment, it includes initial position probe unit 71 and final position to reset probe unit 7 Probe unit 72 is respectively arranged at original position and the final position of the movement of mobile platform 6.Resetting probe unit 7 can be with Can be specifically mirror reflection, diffusing reflection formula, slot using optoelectronic switch, such as infrared photoelectric switch, reflection type optical relay Formula, correlation, optic fiber photoelectric switch etc..
Further include sample rack 61 in further improved embodiment, sample rack 61 can be fixed on mobile platform 6 or It is detachably connected with mobile platform 6;Preferably sample rack 61 is detachably connected with mobile platform 6, if sample rack 61 is fixed on shifting Moving platform 6 then needs the setting-out directly in instrument, and setting-out space can suffer restraints, setting-out efficiency is low, and not easy cleaning, and sample This 61 it is detachable then can outside instrument setting-out, it can be achieved that sample rack quick-replaceable, instrument down time is saved than setting-out on instrument Time improves detection efficiency.
In further improved embodiment, drive component 2 include driving motor 21, synchronous belt 22, synchronizing wheel 23 and The drive connection part 24 being connect with mobile platform 6, to realize that mobile platform 6 moves, wherein stepping may be used in driving motor 21 Motor drives mobile platform 6 to move preferably to coordinate with synchronous belt 22, synchronizing wheel 23.
In further improved embodiment, multiposition positioning component 3 includes that sample reads positioning component 31 and just last position Positioning component 32, as shown in figures 4-6.Sample reads positioning component 31 and mobile platform 6 is positioned at sample information reading, sampling Position, what sample reading assembly 4 will determine that sample rack 61 at this time whether there is sample 62 in this position, while can also read sample This 62 information, such as the present embodiment use bar code scan mode, i.e., there is barcode mark, sample reading assembly 4 to have on sample 62 There is bar code scanning function, when sample rack 61 positions, sample reading assembly 4 can obtain the position of sample rack 61 by scanning With the presence or absence of the information of sample and existing sample 62;Just mobile platform 6 is positioned at initial position by end position positioning component 32 Sample can be reapposed wherein when mobile platform 6 is located at initial position with last position eventually, when mobile platform 6 is located at end eventually Enter next round recurrent state when position to wait for resetting, and when sample rack 61 be it is detachable be set to mobile platform 6 when, first Beginning position or eventually last position can by directly by dismantling, installing new samples frame 61 in a manner of replace sample and improve detection efficiency.
In further improved embodiment, it is sample information reading position that sample, which reads the position that positioning component 31 positions, (judgement sample whether there is or not, read sample information) and sample position (sample) convenient for sampler, and each position is including phase interworking Mutually matched first signalling means, 311 and first trigger 312, sample is arranged in the signalling means and trigger of conjunction, wherein sample position Mutually matched 313 and second trigger 314 of second signal device is arranged in this information reading position.First signalling means 311, second is believed Number 313 stagger arrangement of device is set on support baseboard 1, and the first trigger 312, the second trigger 314 are correspondingly arranged in mobile platform 6 On;Certain signalling means, trigger can also be arranged in turn, i.e. the first signalling means 311,313 stagger arrangement of second signal device are set to On mobile platform 6 and the first trigger 312, the second trigger 314 are correspondingly arranged on support baseboard 1, or are set to detection The other positions of analyzer play the role of trigger signal to make mobile platform 6 position as long as corresponding and cooperating ?.In addition, just last position positioning component 32 is equipped with just last position signalling means, it is initial bit signalling means 321 and whole last position signal respectively Device 322, the two and the 314 mutual cooperation trigger signal of the second trigger for being moved to just last position, make mobile platform 6 be positioned at initially Position or eventually last position.
In further improved embodiment, signalling means is optocoupler or optoelectronic switch, and trigger is chopper blade, this implementation In example, sample reading assembly is one group, and signalling means is one, and chopper blade is a dentation chopper blade, and chopper blade has multiple teeth just It is positioned according to sample placement location on sample rack in mobile platform.As a further improvement, the chopper blade of the second trigger 314 Tooth is formed by the intervals multiple tooth 314b and lacks 314a, tooth 314b lacks whether 314a stops that light passes through to form optical signal triggering with tooth The scarce 314a quantity of signalling means, wherein tooth is identical as 62 quantity of sample, and the sample size as shown in Fig. 2,7 is 16, and tooth lacks 314a numbers Amount is 16;When mobile platform 6 moves, when each tooth, which lacks 314a, passes through second signal device 313, mobile platform 6 positions, sample This reading assembly 4 to sample judge and information is read, and reading finishes mobile platform 6 and continues to move to finish until reading.The The chopper blade of one trigger 312 is dentation chopper blade, and sample size is 16 in the present embodiment, and sampling process is four times altogether, often Secondary four samples, therefore the chopper blade of the first trigger 312 has 4 teeth, when mobile platform 6 moves, when each tooth passes through the Then mobile platform 6 positions when one signalling means 311, and sampler carries out primary sample, and mobile platform 6 continues to move to after sampling Until gross sample.
In further improved embodiment, sample is to be staggered in arrangement, compact-sized saving space, sample reading assembly 4 With sample identification unit 41 and sample information reading unit 42, sample identification unit 41 whether there is sample at positioning for identification This, sample information reading unit 42 is for reading specific sample information, sample identification unit 41 and sample information reading unit 42 are fixed on by the linking arm 43 of L-type on support baseboard 1, and sample reading assembly 4 can be Laser Scanning Equipment, such as reflect Type optical interruption device, wherein sample information reading unit 42 can be specifically bar code scan equipment.Sample identification unit 41 is set to The front of moving direction when sample is read, sample information reading unit 42 are set to the rear of moving direction when sample is read, often When secondary scanning, sample identification unit 41, sample information reading unit 42 scan respectively adjacent sample (adjacent sample refer to from Scanning direction observation does not consider to be staggered in arrangement the sample of adjacent states when whole samples be in same plane), reach substantially together Step judgement sample whether there is and read the purpose of sample information, save sweep time.
In further improved embodiment, multiposition positioning component 3 is set to 6 bottom surface of mobile platform, i.e. multiposition is fixed 3 installation space of hyte part reduces sampling device volume to the greatest extent between mobile platform 6 and support baseboard 1, saves detection analysis instrument Space.Guide rail 5 can select the linear guide in the present embodiment, set on guide rail 5 as needed for the linear guide or ring-shaped guide rail Sliding block 51 is set, sliding block 51 connect with support movable platform with mobile platform and makes the more stable movement of mobile platform.
The present invention also provides a kind of detection analysis instrument with above-mentioned sampling device, sampling device is solid by support baseboard 1 Due to detection analysis instrument.
The above-mentioned detection analysis instrument with sampling device of the present invention is piarhemia parting detector.
The course of work of sampling device of the present invention is as follows:
After placing sample (carrying information bar code mark) first in sample rack 61, sample rack 61 is installed on mobile platform 6; After 2 acceptance test order of drive component, initial position probe unit 71 to sample rack 61 whether there is or not judging, if nothing, instrument without Sample rack is alarmed, and is read if so, then driving the mobile platform 6 being fixed in the linear guide 5 to be steadily moved to sample by drive component 2 4 position of component is taken, and reads positioning component 31 with sample and cooperates, sample is scanned successively, if sample identification unit 41 identification no specimens then record this case, and scanning bar code by sample information reading unit 42 if having sample reads sample letter Breath judges to sample position and by driving successively after the completion of scanning according to the first signalling means 311 of sampling and the cooperation of the first trigger 312 The driving of component 2, positioning, after the completion of sampling, drive component 2 drives mobile platform 6 that sample rack 61 is transported to final position, at this time Second trigger 314 triggers eventually that last position signalling means 322 is to make mobile platform 6 be positioned at final position, after taking sample rack 61 away, Final position probe unit 72 detects no specimen frame, therefore triggering judges that signal, drive component 2 drive mobile platform 6 to move To initial position, the second trigger 314 triggers initial bit signalling means 321 to make mobile platform 6 be positioned at initial position at this time, Waiting recycles next time.Stability low-noise when sample of the present invention frame moves, and controllability height is positioned, particularly suitable for various one's duty The detecting instrument of group sampling can be automatically performed sample information and read and position, and sampling automatic positioning, terminal with compact integral structure It is compact, it is simple to operate.
The present embodiments relate to material, reagent and experimental facilities, unless otherwise instructed, be meet inspection detection The commercial product in field.
The above is merely a preferred embodiment of the present invention, it is noted that for those skilled in the art For, under the premise of not departing from core of the invention technology, improvements and modifications can also be made, these improvements and modifications are also answered Belong to the scope of patent protection of the present invention.With any change in the comparable meaning and scope of claims of the present invention, all It is considered as being included within the scope of the claims.

Claims (17)

1. sampling device, which is characterized in that including support baseboard;
Guide rail is set to the support baseboard;
The mobile platform for carrying sample, is set to the support baseboard, can be moved along the guide rail;
Drive component drives the mobile platform to be moved along the guide rail;
The mobile platform is positioned at desired location by multiposition positioning component;
Sample reading assembly judges whether to have sample on mobile platform and reads sample information;
Wherein, drive component, multiposition positioning component, sample reading assembly are set on support baseboard, or are set to detection Other positions of analyzer.
2. sampling device according to claim 1, which is characterized in that further include resetting probe unit for judging whether to send out Go out the instruction that mobile platform is mobile or resets, the reset probe unit is fixed on the support baseboard, or is fixed on Other positions of detection analysis instrument.
3. sampling device according to claim 2, which is characterized in that the reset probe unit includes initial position detection Unit and final position probe unit are respectively arranged at original position and the final position of the mobile platform movement.
4. sampling device according to claim 1, which is characterized in that further include sample rack, the sample rack is fixed on shifting Moving platform is detachably connected with mobile platform.
5. sampling device according to claim 1, which is characterized in that the multiposition positioning component includes that sample reading is fixed Hyte part and just last position positioning component, the sample read positioning component and the mobile platform are positioned at sample information reading position It sets or the mobile platform is positioned at initial position and eventually last position by sample position, the just last position positioning component.
6. sampling device according to claim 5, which is characterized in that the position that the sample reads positioning component positioning is Sample information reading position and sample position, each position include mutually matched signalling means and trigger.
7. sampling device according to claim 6, which is characterized in that the signalling means is optocoupler or optoelectronic switch, institute It is chopper blade to state trigger, and the chopper blade is dentation chopper blade.
8. sampling device according to claim 6, which is characterized in that mutually matched first signalling means is arranged in sample position With the first trigger, mutually matched second signal device and the second trigger is arranged in sample information reading position;First letter Number device, second signal device stagger arrangement are set on the support baseboard, and first trigger, the second trigger are correspondingly arranged in institute State on mobile platform or the first signalling means, second signal device stagger arrangement are set on mobile platform and the first trigger, second touch Hair device be correspondingly arranged on support baseboard, or be set to detection analysis instrument other positions can cooperate trigger signal to Mobile platform is set to position.
9. sampling device according to claim 8, which is characterized in that the just last position positioning component includes can be with second The mutually matched initial bit signalling means of trigger and eventually last position signalling means.
10. sampling device according to claim 8, which is characterized in that first trigger is quantity and the sampling of tooth The identical dentation chopper blade of number, second trigger are that tooth lacks quantity dentation chopper blade identical with sample size.
11. sampling device according to claim 1, which is characterized in that the sample reading assembly includes specimen discerning list Member and sample information reading unit are fixed on the support baseboard by linking arm, and sample identification unit is set to sample reading The front of moving direction when taking, sample information reading unit are set to the rear of moving direction when sample is read.
12. sampling device according to claim 11, which is characterized in that sample identification unit can laser scanning, sample letter Cease reading unit can bar code scan, sample has a recognizable bar code information, and every time scanning when sample identification unit, sample information Reading unit scans adjacent sample respectively.
13. sampling device according to claim 1, which is characterized in that the multiposition positioning component is set to the shifting Moving platform bottom surface.
14. sampling device according to claim 1, which is characterized in that the driving component includes driving motor, synchronization Band, synchronizing wheel and the drive connection part being connect with the mobile platform, the driving motor are stepper motor.
15. detection analysis instrument, which is characterized in that have claim 1~14 any one of them sampling device.
16. detection analysis instrument according to claim 15, which is characterized in that the sampling device is installed by support baseboard In detection analysis instrument.
17. detection analysis instrument according to claim 15, which is characterized in that it is piarhemia parting detector, it is each for measuring The cholesterol level of class lipoprotein.
CN201810796055.6A 2018-07-19 2018-07-19 Sampling device and detection analysis instrument with the device Pending CN108761109A (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Address after: 330000 the three or four tier of science and technology 2 building, electronic information industry park, Nanchang economic and Technological Development Zone, Nanchang, Jiangxi.

Applicant after: Jiangxi Meikang Shengde Biotechnology Co., Ltd

Address before: 330000 the three or four tier of science and technology 2 building, electronic information industry park, Nanchang economic and Technological Development Zone, Nanchang, Jiangxi.

Applicant before: JIANGXI WEIRUI BIOTECHNOLOGY Co.,Ltd.