CN206323949U - A kind of experiment mice metabolic cage for being used to collect sterile urine - Google Patents

A kind of experiment mice metabolic cage for being used to collect sterile urine Download PDF

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Publication number
CN206323949U
CN206323949U CN201621415457.XU CN201621415457U CN206323949U CN 206323949 U CN206323949 U CN 206323949U CN 201621415457 U CN201621415457 U CN 201621415457U CN 206323949 U CN206323949 U CN 206323949U
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China
Prior art keywords
urine
funnel
catheter
cage
separating device
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CN201621415457.XU
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Chinese (zh)
Inventor
周晨辰
王怡
薛澄
顾向晨
徐艳秋
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of TCM
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of TCM
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Abstract

The utility model is related to a kind of experiment mice metabolic cage for being used to collect sterile urine, including experimental cage, device for feeding, water supply device, urine and excrement separating device, support, the experimental cage includes sieve aperture, air-vent, device for feeding putting hole, water supply device putting hole, the urine and excrement separating device includes the first funnel, second funnel, catheter, first funnel includes the first sieve plate, second sieve plate, second funnel includes filter membrane, catheter, closure, first funnel, second funnel, catheter is detachably connected successively from top to bottom, the support is provided with standing groove, urine and excrement separating device is arranged in standing groove, experimental cage is arranged on urine and excrement separating device top.It the advantage is that, urine and excrement separating device and experimental cage can be effectively fixed with support;Urine and excrement separating device makes fecaluria separation thorough by two layers of sieve plate and one layer of filter membrane;Seal is good, it is to avoid urine is volatilized;Urine and excrement separating device is flowed into without swill or raffinate, it is to avoid pollution.

Description

A kind of experiment mice metabolic cage for being used to collect sterile urine
Technical field
The utility model is related to experiment apparatus technical field, specifically, is a kind of experiment for being used to collect sterile urine Mouse metabolism cage.
Background technology
Mouse is small, and growth and breeding is fast, and low cost, it is easy to control is used as medical experiment animal.The urine inspection of mouse Survey is a more crucial physical and chemical index.Therefore the urine for collecting mouse is a very crucial step.Separated with fecaluria The method that device directly collects animal metabolism product is Metabolic cage method.Metabolic cage is used for the urine for collecting experimental animal natural excrement And excrement, it is a kind of closed rearging cage to gather experimental animal excreta of particular design.Metabolic cage of laboratory mice is special Rearging cage for collecting experimental mouse excreta, for the internal metabolism of experimental mouse, provides pleasant for experimental mouse Living environment, can be quantified to experimental mouse drinking-water, diet, allow experimental mouse natural metabolism in metabolic cage, and metabolic cage divides The fecaluria that can make experimental mouse from device is separated, so as to carry out metabolism research of the various medicines in experimental mouse body.
Chinese utility model patent ZL201310335359.X discloses a kind of Simple mouse metabolism cage, this metabolic cage bag Include below raising area, metabolism area, metabolism area to be netted, under to connect and receive collector under funnel, funnel.This metabolic cage is simple in construction, It is with low cost, fecaluria separation can be carried out to a certain extent.But this metabolic cage need operating personnel by mouse from raise area Metabolism area is put into, it is necessary to which operating personnel's moment is paid close attention to;Not thoroughly, urine is easily mixed with excrement in collecting pipe for fecaluria separation;Entirely Device does not take in closing measure, collecting pipe that urine is volatile, causes urinary fractions change in concentration.
Chinese invention patent ZL201310631495.3 discloses a kind of rat metabolism cage, this metabolic cage include hook, Experimental cage, fecal collecting device, urine separation device, urine collecting device, the gentle PLC in day, urine separation device corner hangs over excrement The corner of collection device, urine collecting device is arranged on below urine separation device, and balance is arranged on below urine collecting device, and balance is controlled with PLC Device is connected.This metabolic cage is easy to move, automatic test experiments data.But this metabolic cage sealing is poor;It is solid using hook Determine experimental cage, make experimental cage unstable;The residue of water, food is not handled, these residues is mixed into fecaluria, causes Experimental data is inaccurate;Urine separation device hangs over fecal collecting device, structural instability, easily make fecaluria in fecal collecting device and Trickle down urine separation device contact position.
Therefore, need badly one kind can effectively fix metabolic cage, fecaluria separation thoroughly, seal is good, anhydrous or food The metabolic cage that residue is mixed into, and had not been reported at present on this metabolic cage.
The content of the invention
The purpose of this utility model is that there is provided a kind of experiment for being used to collect sterile urine for deficiency of the prior art Mouse metabolism cage.
To achieve the above object, the utility model is adopted the technical scheme that:
A kind of experiment mice metabolic cage for being used to collect sterile urine, including experimental cage, device for feeding, water supply device, excrement Separator, support are urinated, the experimental cage includes sieve aperture, air-vent, device for feeding putting hole, water supply device putting hole, described Urine and excrement separating device includes the first funnel, the second funnel, catheter, and first funnel includes the first sieve plate, the second sieve plate, institute Stating the second funnel includes filter membrane, catheter, closure, and first funnel, the second funnel, catheter successively may be used from top to bottom Dismounting connection, the support is provided with standing groove, and urine and excrement separating device is arranged in standing groove, and experimental cage is arranged on fecaluria separation dress Put top.
Further, the urine and excrement separating device is by hating liquid material to be made.
Further, the screen-aperture is more than the first hole diameter of sieve (perforated) plate, and the first hole diameter of sieve (perforated) plate is more than the second hole diameter of sieve (perforated) plate.
Further, first funnel, the second funnel are taper.
Further, the filter membrane is miillpore filter.
Further, the experiment mice metabolic cage also includes fixed dam, and the fixed dam two ends protrusion can block In internal stent, fixed dam is provided with catheter standing groove.
Further, the experiment mice metabolic cage also includes refrigerating plant, and the refrigerating plant is arranged on catheter Bottom, refrigerating plant is provided with catheter standing groove, holding chamber.
Further, the refrigerating plant is refrigerating box.
The utility model advantage is:
1st, urine and excrement separating device and experimental cage can be effectively fixed with support, prevents mouse when experimental cage is moved, made whole Device is rocked;
2nd, urine and excrement separating device makes fecaluria separation thorough by two layers of sieve plate and one layer of filter membrane;
3rd, seal is good, it is to avoid urine is volatilized;
4th, urine and excrement separating device is flowed into without swill or raffinate, it is to avoid pollution.
Brief description of the drawings
Accompanying drawing 1 is a kind of signal for being used to collect the experimental cage of the experiment mice metabolic cage of sterile urine of the present utility model Figure.
Accompanying drawing 2 is a kind of showing for the first funnel for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model It is intended to.
Accompanying drawing 3 is a kind of showing for the first sieve plate for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model It is intended to.
Accompanying drawing 4 is a kind of showing for the second funnel for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model It is intended to.
Accompanying drawing 5 is a kind of signal for being used to collect the catheter of the experiment mice metabolic cage of sterile urine of the present utility model Figure.
Accompanying drawing 6 is a kind of signal for being used to collect the support of the experiment mice metabolic cage of sterile urine of the present utility model Figure.
Accompanying drawing 7 is a kind of showing for fixed dam for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model It is intended to.
Accompanying drawing 8 is a kind of device for feeding signal for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Figure.
Accompanying drawing 9 is a kind of water supply device signal for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Figure.
Accompanying drawing 10 is a kind of experimental cage assembling for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Schematic diagram.
Accompanying drawing 11 is a kind of fecaluria separation dress for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Put assembling schematic diagram
Accompanying drawing 12 is that a kind of support assembling for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model is shown It is intended to.
Accompanying drawing 13 is a kind of schematic diagram for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model.
Accompanying drawing 14 is another refrigerating plant for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Closure state schematic diagram.
Accompanying drawing 15 is another refrigerating plant for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Opening schematic diagram.
Accompanying drawing 16 is another support assembling for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Schematic diagram
Accompanying drawing 17 is another schematic diagram for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model.
Embodiment
The embodiment that the utility model is provided is elaborated below in conjunction with the accompanying drawings.
The reference and part being related in accompanying drawing are as follows:
1. the funnel of experimental cage 2. first
3. the catheter of the second funnel 4.
5. the fixed dam of support 6.
7. the water supply device of device for feeding 8.
9. refrigerating plant
11. the air-vent of sieve aperture 12.
13. the water supply device putting hole of device for feeding putting hole 14.
21. the sieve plate of the first sieve plate 22. second
31. the catheter of filter membrane 32.
33. closure
51. standing groove
61. catheter standing groove
71. the storage food food guid device of tank 72.
73. the feeding groove of feeding room 74.
81. the aqueduct of water tank 82.
83. raffinate collecting pipe
91. the holding chamber of catheter standing groove 92.
Embodiment 1
A kind of experiment mice metabolic cage for being used to collect sterile urine of the present utility model, including the separation of experimental cage 1, fecaluria Device, support 5, fixed dam 6, device for feeding 7, water supply device 8;Reference picture 1, the experimental cage 1 includes sieve aperture 11, air-vent 12nd, device for feeding putting hole 13, water supply device putting hole 14;Reference picture 2-5, the urine and excrement separating device include the first funnel 2, Second funnel 3, catheter 4, the urine and excrement separating device, which is, hates liquid material to be made, and first funnel 1 includes the first sieve plate 21st, the second sieve plate 22, second funnel 3 includes filter membrane 31, catheter 32, closure 33, first funnel 2, second Funnel 3, catheter 4 are detachably connected successively from top to bottom, and first funnel 2, the second funnel 3 are taper;Reference picture 6, The support 5 is provided with standing groove 51;With reference to 13, urine and excrement separating device is arranged on 51 in standing groove, and experimental cage 1 is arranged on fecaluria point From device top;Reference picture 8, device for feeding 7 eats tank 71, food guid device 72, feeding room 73, feeding groove 74 including storing up, storage food tank 71, Food guid device 72, feeding room 73 are sequentially connected from top to bottom, and feeding groove 74 is arranged in feeding room 73, the opening alignment of food guid device 72 Feeding groove 74;Reference picture 9, water supply device 8 includes water tank 81, aqueduct 82, raffinate collecting pipe 83, water tank 81, aqueduct 82nd, raffinate collecting pipe 83 is sequentially connected from top to bottom;Reference picture 7, the two ends of fixed dam 6 protrusion, may be stuck in inside support 5, Gu Determine baffle plate 6 and be additionally provided with catheter standing groove 61.
Reference picture 10-13, a kind of assembling for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Journey is as follows:Fixed dam 6 is stuck in inside support 5;First funnel 2, the second funnel 3, catheter 4 are connected successively from top to bottom Connect, catheter 4 is aligned and is placed in the catheter standing groove 61 of fixed dam 6, the standing groove 51 of support 5 blocks the first leakage Bucket 2;After device for feeding 7 and water supply device 8 are placed in experimental cage 1, whole experimental cage 1 is aligned and fecaluria separation is placed on Device top.
A kind of application method of experiment mice metabolic cage for collecting sterile urine of the present utility model is as follows:Toward storage food Accommodating food and water in tank 71, water tank 81, mouse is placed in experimental cage 1;When mouse is drained, due to sieve aperture 11 Aperture is as big as possible in the case of not escaped for guarantee mouse, therefore excrement, urine can be fallen from experimental cage 1 completely;First Small many in the aperture of the aperture ratio sieve aperture 11 of sieve plate 21 so that the excrement fallen is largely retained by the first sieve plate 21;Some The smaller excrement of grain is fallen on the second sieve plate 22 by the first sieve plate 21, due to the first sieve plate of aperture ratio 21 of the second sieve plate 22 more It is small, therefore, remaining excrement can be retained;After some turn into powdered excrement by the second sieve plate 22, due in the second funnel 3 Provided with filter membrane 31, because filter membrane 31 is miillpore filter, it can stop that excrement drops down onto catheter 4 under continuing completely;Due to whole Urine and excrement separating device is by hating liquid material to be made, therefore, when urine is fallen from experimental cage 1, is filled without fecaluria separation is attached to Inside is put, the second funnel 3 is flow to from the first funnel 2, then catheter 4, closure 33 are flow to from the second funnel 3 by catheter 32 Effect place urine evaporation;Last catheter 4 collects the urine entirely without excrement.
Embodiment 2
A kind of experiment mice metabolic cage for being used to collect sterile urine of the present utility model, including the separation of experimental cage 1, fecaluria Device, support 5, device for feeding 7, water supply device 8, refrigerating plant 9, reference picture 1, the experimental cage 1 include sieve aperture 11, air-vent 12nd, device for feeding putting hole 13, water supply device putting hole 14;Reference picture 2-5, the urine and excrement separating device include the first funnel 2, Second funnel 3, catheter 4, the urine and excrement separating device, which is, hates liquid material to be made, and first funnel 1 includes the first sieve plate 21st, the second sieve plate 22, second funnel 3 includes filter membrane 31, catheter 32, closure 33, first funnel 2, second Funnel 3, catheter 4 are detachably connected successively from top to bottom, and first funnel 2, the second funnel 3 are taper;Reference picture 6, The support 5 is provided with standing groove 51;With reference to 13, urine and excrement separating device is arranged on 51 in standing groove, and experimental cage 1 is arranged on fecaluria point From device top;Reference picture 8, device for feeding 7 eats tank 71, food guid device 72, feeding room 73, feeding groove 74 including storing up, storage food tank 71, Food guid device 72, feeding room 73 are sequentially connected from top to bottom, and feeding groove 74 is arranged in feeding room 73, the opening alignment of food guid device 72 Feeding groove 74;Reference picture 9, water supply device 8 includes water tank 81, aqueduct 82, raffinate collecting pipe 83, water tank 81, aqueduct 82nd, raffinate collecting pipe 83 is sequentially connected from top to bottom;Reference picture 14-15, refrigerating plant 9 be refrigerating box, including catheter place Groove 91, holding chamber 92.
Reference picture 10,16-17, a kind of assembling for being used to collect the experiment mice metabolic cage of sterile urine of the present utility model Process is as follows:Ice bag is placed in toward holding chamber 92, refrigerating plant 9 is stuck in inside support 5;By the first funnel 2, the second funnel 3, Catheter 4 is sequentially connected from top to bottom, and catheter 4 is aligned and is placed in the catheter standing groove 91 of refrigerating plant 9, support 5 standing groove 51 blocks the first funnel 2;After device for feeding 7 and water supply device 8 are placed in experimental cage 1, by whole experimental cage 1 is aligned and is placed on urine and excrement separating device top.
A kind of application method of experiment mice metabolic cage for collecting sterile urine of the present utility model is as follows:Toward storage food Accommodating food and water in tank 71, water tank 81, mouse is placed in experimental cage 1;When mouse is drained, due to sieve aperture 11 Aperture is as big as possible in the case of not escaped for guarantee mouse, therefore excrement, urine can be fallen from experimental cage 1 completely;First Small many in the aperture of the aperture ratio sieve aperture 11 of sieve plate 21 so that the excrement fallen is largely retained by the first sieve plate 21;Some The smaller excrement of grain is fallen on the second sieve plate 22 by the first sieve plate 21, due to the first sieve plate of aperture ratio 21 of the second sieve plate 22 more It is small, therefore, remaining excrement can be retained;After some turn into powdered excrement by the second sieve plate 22, due in the second funnel 3 Provided with filter membrane 31, because filter membrane 31 is miillpore filter, it can stop that excrement drops down onto catheter 4 under continuing completely;Due to whole Urine and excrement separating device is by hating liquid material to be made, therefore, when urine is fallen from experimental cage 1, is filled without fecaluria separation is attached to Inside is put, the second funnel 3 is flow to from the first funnel 2, then catheter 4, closure 33 are flow to from the second funnel 3 by catheter 32 Effect be to prevent urine evaporation;The effect of refrigerating plant 9 is to reduce urine evaporation and reduction bacteria breed;Last catheter 4 Collect the urine entirely without excrement.
A kind of advantage of experiment mice metabolic cage for collecting sterile urine of the present utility model is can have with support The fixed urine and excrement separating device of effect and experimental cage, prevent that mouse from, when experimental cage is moved, rock whole device;Urine and excrement separating device By two layers of sieve plate and one layer of filter membrane, make fecaluria separation thorough;Seal is good, it is to avoid urine is volatilized;It is residual without food Slag or raffinate flow into urine and excrement separating device, it is to avoid pollution.
The above is only preferred embodiment of the present utility model, it is noted that for the common skill of the art Art personnel, on the premise of the utility model method is not departed from, can also make some improvement and supplement, and these improve and supplemented Also it should be regarded as protection domain of the present utility model.

Claims (8)

1. a kind of experiment mice metabolic cage for being used to collect sterile urine, it is characterised in that including experimental cage, device for feeding, feed Water installations, urine and excrement separating device, support, the experimental cage include sieve aperture, air-vent, device for feeding putting hole, water supply device and put Put hole, the urine and excrement separating device includes the first funnel, the second funnel, catheter, first funnel includes the first sieve plate, the Two sieve plates, second funnel includes filter membrane, catheter, closure, and first funnel, the second funnel, catheter are from upper It is detachably connected successively under, the support is provided with standing groove, urine and excrement separating device is arranged in standing groove, and experimental cage is arranged on Urine and excrement separating device top.
2. metabolic cage according to claim 1, it is characterised in that the urine and excrement separating device is made by hating liquid material.
3. metabolic cage according to claim 1, it is characterised in that the screen-aperture is more than the first hole diameter of sieve (perforated) plate, first Hole diameter of sieve (perforated) plate is more than the second hole diameter of sieve (perforated) plate.
4. metabolic cage according to claim 1, it is characterised in that first funnel, the second funnel are taper.
5. metabolic cage according to claim 1, it is characterised in that the filter membrane is miillpore filter.
6. according to any described metabolic cages of claim 1-5, it is characterised in that also including fixed dam, the fixed dam Two ends are protruded, and can be stuck in internal stent, and fixed dam is provided with catheter standing groove.
7. according to any described metabolic cages of claim 1-5, it is characterised in that also including refrigerating plant, the refrigerating plant Catheter bottom is arranged on, refrigerating plant is provided with catheter standing groove, holding chamber.
8. metabolic cage according to claim 7, it is characterised in that the refrigerating plant is refrigerating box.
CN201621415457.XU 2016-12-22 2016-12-22 A kind of experiment mice metabolic cage for being used to collect sterile urine Active CN206323949U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112586372A (en) * 2020-12-25 2021-04-02 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 Mouse metabolism cage
CN113796325A (en) * 2021-09-22 2021-12-17 中国科学院深圳先进技术研究院 Experimental mouse excrement collection device
CN115119759A (en) * 2022-05-24 2022-09-30 温州医科大学 Independent ventilation sealing cage
WO2023044611A1 (en) * 2021-09-22 2023-03-30 中国科学院深圳先进技术研究院 Laboratory mouse excrement collecting device

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112586372A (en) * 2020-12-25 2021-04-02 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 Mouse metabolism cage
CN113796325A (en) * 2021-09-22 2021-12-17 中国科学院深圳先进技术研究院 Experimental mouse excrement collection device
WO2023044611A1 (en) * 2021-09-22 2023-03-30 中国科学院深圳先进技术研究院 Laboratory mouse excrement collecting device
CN115119759A (en) * 2022-05-24 2022-09-30 温州医科大学 Independent ventilation sealing cage
CN115119759B (en) * 2022-05-24 2023-05-30 温州医科大学 Independent ventilation sealing cage

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