CN113796325A - Experimental mouse excrement collection device - Google Patents

Experimental mouse excrement collection device Download PDF

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Publication number
CN113796325A
CN113796325A CN202111107500.1A CN202111107500A CN113796325A CN 113796325 A CN113796325 A CN 113796325A CN 202111107500 A CN202111107500 A CN 202111107500A CN 113796325 A CN113796325 A CN 113796325A
Authority
CN
China
Prior art keywords
baffle
box body
mouse
feeding device
urine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202111107500.1A
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Chinese (zh)
Inventor
景晓源
刘欣安
王立平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Institute of Advanced Technology of CAS filed Critical Shenzhen Institute of Advanced Technology of CAS
Priority to CN202111107500.1A priority Critical patent/CN113796325A/en
Publication of CN113796325A publication Critical patent/CN113796325A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals
    • A01K1/031Cages for laboratory animals; Cages for measuring metabolism of animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/035Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
    • A01K1/0356Feeding or drinking devices associated with cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0038Devices for taking faeces samples; Faecal examination devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/007Devices for taking samples of body liquids for taking urine samples

Abstract

The invention relates to an experimental mouse excrement collecting device. An experimental mouse excrement collecting device comprises a box body, wherein a cover plate is arranged at the top of the box body, and three layers of baffles are arranged in the box body from top to bottom; the first layer of partition is horizontally arranged, and a space enclosed by the first layer of partition, the box body and the cover plate is a mouse placing area; the second baffle and the third baffle are sieve plates and used for preventing mouse excrement from falling down, the second baffle and the third baffle are obliquely arranged and can be drawn out from one side of the box body; a urine collecting funnel is arranged below the third partition, a urine collecting pipe is fixed below the funnel, and the urine collecting pipe is connected with the collecting bottle; a water feeding device and a feeding device are arranged on the outer side of the box body, a feeding trough is fixedly arranged in the mouse placing area, and a food outlet of the feeding device extends into the feeding trough; the water outlet of the water feeding device extends into the mouse placing area from the side wall of the box body. The invention can effectively separate the feces and urine of the mice.

Description

Experimental mouse excrement collection device
Technical Field
The invention relates to an experimental mouse excrement collecting device.
Background
Urine detection of mice is a relatively key physicochemical index. Therefore, collecting urine from mice is a critical step. The method for directly collecting animal metabolites by using a feces-urine separation device is a metabolic cage method.
The Chinese utility model patent ZL201310335359.X discloses a simple mouse metabolism cage, and the metabolism cage comprises a feeding area and a metabolism area, wherein the lower part of the metabolism area is net-shaped, a funnel is connected downwards, and a collecting pipe is connected downwards. The metabolism cage has simple structure and low cost, and can separate excrement and urine to a certain extent. However, the metabolism cage needs operators to put the mice from the feeding area to the metabolism area, and the operators need to pay attention to the metabolism area all the time; the excrement and urine are not completely separated, and the urine in the collecting pipe is easily mixed with the excrement; the whole device does not adopt a sealing measure, and the urine in the collecting pipe is volatile, so that the concentration of the urine component is changed.
Disclosure of Invention
In order to make up the defects of the prior art, the invention provides a device for collecting the excrement of an experimental mouse, which can effectively separate the excrement and urine of the mouse.
The technical scheme for solving the problems is as follows:
an experimental mouse excrement collection device which is characterized in that:
the box body is provided with a cover plate at the top, and three layers of baffles are arranged in the box body from top to bottom;
the first layer of partition is horizontally arranged, and a space enclosed by the first layer of partition, the box body and the cover plate is a mouse placing area; the second baffle and the third baffle are sieve plates and used for preventing mouse excrement from falling down, the second baffle and the third baffle are obliquely arranged and can be drawn out from one side of the box body; a urine collecting funnel is arranged below the third partition, a urine collecting pipe is fixed below the funnel, and the urine collecting pipe is connected with the collecting bottle;
a water feeding device and a feeding device are arranged on the outer side of the box body, a feeding trough is fixedly arranged in the mouse placing area, and a food outlet of the feeding device extends into the feeding trough; the water outlet of the water feeding device extends into the mouse placing area from the side wall of the box body.
Furthermore, a slide way is arranged in the box body, and the second separating baffle and the third separating baffle are respectively put in or taken out through the slide way.
Furthermore, the second baffle and the third baffle are provided with handles, so that the second baffle and the third baffle can be conveniently drawn out of the box body.
Furthermore, the second baffle and the third baffle are provided with baffle plates on one side relative to the handle.
Furthermore, one side of the cover plate is hinged with the box body, a buckle is arranged on the side opposite to the hinged side of the cover plate, and the cover plate can be fixed with the box body through the buckle.
Furthermore, the water feeding device comprises a water bottle with scales and a water outlet pipe connected with the water bottle, the end part of the water outlet pipe is a water outlet nozzle, the water outlet nozzle comprises a ball, the diameter of the ball is smaller than that of the water outlet pipe, the side wall of the end part of the water outlet pipe is an arc surface, and the surface of the arc surface is completely attached to the surface of the water outlet pipe when the arc surface is in contact with the ball.
Furthermore, the feeding device is a funnel, and a food outlet at the lower part of the funnel extends into the food groove.
Furthermore, the side wall of the collecting bottle is provided with scale marks, the bottle mouth of the collecting bottle is provided with a rubber plug, and the middle part of the rubber plug is provided with an inlet.
Further, the surface of the urine collecting funnel is coated with lyophobic material.
Furthermore, the bottom of the box body is provided with a plurality of rollers, so that the box body is convenient to move.
The invention has the advantages that:
1) the mouse placing area is provided with the water feeding device and the feeding device, and is also integrated with the urine and excrement separating and collecting device, so that the mouse does not need to be transferred when the urine and the excrement are collected;
2) the second baffle and the third baffle can be extracted from the box body, so that the excrement on the baffles can be conveniently collected;
3) according to the invention, the second baffle and the third baffle are obliquely arranged, so that excrement falling on the baffles can roll down to the lower side of the baffles, and when urine of a mouse falls down, the excrement on the baffles can not absorb the urine, so that the urine can be completely collected;
4) the surface coating lyophobic material of urine collection funnel is favorable to the urine to be collected completely.
Drawings
FIG. 1 is a view showing the construction of an excreta collecting device for experimental mice according to the present invention;
FIG. 2 is a block diagram of the collection bottle of FIG. 1;
FIG. 3 is a block diagram of the water feeder of FIG. 1;
fig. 4 is a structural view of the second barrier of fig. 1.
In the figure: 1. the device comprises a box body, a cover plate, a first layer of baffle, a second layer of baffle, a third layer of baffle, a fourth layer of baffle, a fourth layer of baffle, a fourth layer, a baffle, a fourth layer, a fourth layer, a urine collecting funnel, a urine collecting tube, a urine collecting; 13. a baffle plate; 14. buckling; 15. a water bottle; 16. a water outlet pipe; 17. a water outlet nozzle; 18. a ball bearing; 19. a collection bottle; 20. a rubber plug; 21. and a roller.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention.
The invention provides an experimental mouse excrement collecting device which comprises a box body 1, wherein a cover plate 2 is arranged at the top of the box body 1, and three layers of baffles are arranged in the box body 1 from top to bottom; the first layer of barrier 3 is horizontally arranged, and the space enclosed by the first layer of barrier, the box body 1 and the cover plate 2 is a mouse placing area; the second separation baffle 4 and the third separation baffle 5 are sieve plates, the second separation baffle 4 and the third separation baffle 5 are used for preventing mouse excrement from falling down, the second separation baffle 4 and the third separation baffle 5 are obliquely arranged, and the second separation baffle 4 and the third separation baffle 5 can be drawn out from one side of the box body 1; the third separates and keeps off 5 below and sets up urine collection funnel 6, and the fixed urine collecting pipe 7 in urine collection funnel 6 below, urine collecting pipe 7 are connected with receiving flask 19.
A water feeding device 8 and a feeding device 9 are arranged on the outer side of the box body 1, a feeding trough 11 is fixedly arranged in the mouse placing area, and a food outlet 10 of the feeding device 9 extends into the feeding trough 11; the water outlet of the water feeding device 8 extends into the mouse placing area from the side wall of the box body 1.
The mouse placing area is provided with the water feeding device 8 and the feeding device 9, and is also integrated with the urine and excrement separating and collecting device, so that the mouse does not need to be transferred when the urine and the excrement are collected. The feeding means 8 and 9 can be arranged on either side of the housing 1.
According to the invention, the second partition 4 and the third partition 5 are obliquely arranged, so that excrement falling on the partitions can roll to the lower side of the partitions, and when urine of a mouse falls, the excrement on the partitions cannot absorb and influence the urine to fall into the urine collecting funnel 6, so that complete collection of the urine is facilitated.
In a preferred embodiment of the present invention, a slide way is provided in the box body 1, and the second barrier 4 and the third barrier 5 are respectively put in or drawn out through the slide way.
The sizes of the sieve pores on the second baffle 4 and the third baffle 5 can be the same or different, and excrement can be prevented from falling off; when the aperture of the third baffle 5 is different from that of the second baffle 4, the diameter of the sieve pore on the third baffle is smaller than that of the sieve pore on the second baffle.
When extracting mouse excrement and urine, separate the second and keep off 4 and take out, press from both sides the mouse excrement and urine with tweezers, the third separates and keeps off 5 motionless, even the mouse is discharged excrement and urine this moment, also only can drop on the third separates and keeps off 5, also need not worry that excrement and urine falls into in urine collection funnel 6. And (3) collecting the excrement on the second separation block 4, sending the second separation block 4 into the original position along the slide way, if the excrement falls on the third separation block 5, drawing out the third separation block 5, and clamping the excrement of the mouse by using tweezers.
The box body 1 of the present invention may be made of a transparent material, or may be made of a mesh material. The water feeding device 8 and the feeding device 9 can be fixed on the side wall of the box body 1 through a mounting frame.
In a preferred embodiment of the present invention, the second partition 4 and the third partition 5 are provided with handles 12, which are convenient for an operator to grasp with hands to pull out the second partition from the box 1.
In a preferred embodiment of the present invention, the second barrier 4 and the third barrier 5 are provided with a baffle 13 on a side opposite to the handle 12. The baffle 13 blocks and collects the feces falling from the second and third partitions 4 and 5.
As a preferred embodiment of the invention, one side of the cover plate 2 is hinged with the box body 1, and the side opposite to the hinged side is provided with a buckle 14, and the cover plate 2 can be fixed with the box body 1 through the buckle 14. When the mouse is transferred, the operator unlocks the buckle 14 and turns over the cover plate 2.
As a preferred embodiment of the invention, the water feeding device 8 comprises a water bottle 15 with scales and a water outlet pipe 16 connected with the water bottle, the water outlet pipe 16 is an inclined bent pipe, the end part of the water outlet pipe 16 is a water outlet nozzle 17, the water outlet nozzle 17 comprises a ball 18, the diameter of the ball 18 is smaller than that of the water outlet pipe 16, the side wall of the end part of the water outlet pipe 16 is an arc surface, and the surface of the arc surface is completely attached when the arc surface is contacted with the ball 18.
When the mouse drinks water, lick ball 18, overcome the gravity and the water resistance of ball 18, ball 18 moves upwards, and water flows out, and when not drinking water, ball 18 rolls down by the dead weight, and ball 18 blocks rivers with 16 tip lateral walls laminating of outlet pipe.
In a preferred embodiment of the present invention, the feeding device 9 is a funnel structure, and the food outlet 10 at the lower part of the feeding device 9 extends into the food groove 11.
The upper portion opening of feeding device 9 is put into with food to operating personnel ration, and food landing downwards, when food piles up in trough 11, and food is the landing no longer, and the mouse is eaten the food in trough 11 after, and food just can follow out-of-stock mouth 10 and flow out, when avoiding food too much, the mouse spills food on first layer separates and keeps off 3.
As a preferred embodiment of the invention, the side wall of the collecting bottle 19 is provided with scale marks, so that the urine volume of the mouse can be conveniently recorded; the bottleneck department of receiving bottle 19 is equipped with rubber buffer 20, and rubber buffer 20 middle part is equipped with the entry, and urine collecting pipe 7 stretches into rubber buffer 20 middle part and is equipped with in the entry, plays sealed effect, and rubber buffer 20 prevents that the urine from volatilizing.
As a preferred embodiment of the invention, the surface of the urine collection funnel 6 is coated with lyophobic material, so that urine is prevented from being retained on the surface of the urine collection funnel 6, the loss of urine is reduced, and the urine is accurately collected. The edge of the urine collection funnel 6 is fixed to the inner wall of the housing 1 and the collection bottle 19 can be fixed by fixing means.
As a preferred embodiment of the present invention, the bottom of the box body 1 is provided with a plurality of rollers 21, which facilitate the movement of the collecting device by the operator.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent structures or equivalent flow transformations made by using the contents of the specification and the drawings, or applied directly or indirectly to other related systems, are included in the scope of the present invention.

Claims (10)

1. An experimental mice excrement collection device which characterized in that:
the box body (1) is provided with a cover plate (2) at the top, and three layers of baffles are arranged in the box body (1) from top to bottom;
the first layer of baffles (3) is horizontally arranged, and the space enclosed by the baffles, the box body (1) and the cover plate (2) is a mouse placing area; the second separation baffle (4) and the third separation baffle (5) are sieve plates, the second separation baffle (4) and the third separation baffle (5) are used for preventing the excrement of the mouse from falling down, the second separation baffle (4) and the third separation baffle (5) are obliquely arranged, and the second separation baffle (4) and the third separation baffle (5) can be drawn out from one side of the box body (1); a urine collecting funnel (6) is arranged below the third partition (5), a urine collecting pipe (7) is fixed below the urine collecting funnel (6), and the urine collecting pipe (7) is connected with a collecting bottle (19);
a water feeding device (8) and a feeding device (9) are arranged on the outer side of the box body (1), a feeding trough (11) is fixedly arranged in the mouse placing area, and a food outlet (10) of the feeding device (9) extends into the feeding trough (11); the water outlet of the water feeding device (8) extends into the mouse placing area from the side wall of the box body (1).
2. The laboratory mouse excrement collection device according to claim 1, wherein:
the box body (1) is internally provided with a slideway, and the second baffle (4) and the third baffle (5) are respectively put in or taken out through the slideway.
3. The laboratory mouse excrement collection device according to claim 2, wherein:
the second separating baffle (4) and the third separating baffle (5) are respectively provided with a handle (12), so that the second separating baffle and the third separating baffle can be conveniently drawn out from the box body (1).
4. The laboratory mouse excrement collection device according to claim 3, wherein:
baffle plates (13) are arranged on one sides, relative to the handle (12), of the second separation baffle (4) and the third separation baffle (5).
5. The laboratory mouse excrement collecting device according to any one of claims 1 to 4, wherein:
one side of the cover plate (2) is hinged with the box body (1), a buckle (14) is arranged on the side opposite to the hinged side of the cover plate, and the cover plate (2) can be fixed with the box body (1) through the buckle (14).
6. The laboratory mouse excrement collection device according to claim 5, wherein:
the water feeding device (8) comprises a water bottle (15) with scales and a water outlet pipe (16) connected with the water bottle, the end part of the water outlet pipe (16) is provided with a water outlet nozzle (17), the water outlet nozzle (17) comprises a ball (18), the diameter of the ball (18) is smaller than that of the water outlet pipe (16), the side wall of the end part of the water outlet pipe (16) is an arc surface, and the surface of the arc surface is completely attached to the surface of the ball (18) when the arc surface is contacted with the ball.
7. The laboratory mouse excrement collection device according to claim 6, wherein:
the feeding device (9) is of a funnel structure, and a food outlet (10) at the lower part of the feeding device (9) extends into the food groove (11).
8. The laboratory mouse excrement collection device according to claim 7, wherein:
be equipped with the scale mark on the lateral wall of receiving flask (19), the bottleneck department of receiving flask (19) is equipped with rubber buffer (20), and rubber buffer (20) middle part is equipped with the entry.
9. The laboratory mouse excrement collection device according to claim 8, wherein:
the surface of the urine collecting funnel (6) is coated with lyophobic material.
10. The laboratory mouse excrement collection device according to claim 9, wherein:
the bottom of box (1) is equipped with a plurality of gyro wheels (21), conveniently removes.
CN202111107500.1A 2021-09-22 2021-09-22 Experimental mouse excrement collection device Pending CN113796325A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111107500.1A CN113796325A (en) 2021-09-22 2021-09-22 Experimental mouse excrement collection device

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Application Number Priority Date Filing Date Title
CN202111107500.1A CN113796325A (en) 2021-09-22 2021-09-22 Experimental mouse excrement collection device

Publications (1)

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CN113796325A true CN113796325A (en) 2021-12-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114711826A (en) * 2022-02-21 2022-07-08 四川大学华西医院 Stool sampling device
CN116250490A (en) * 2023-05-09 2023-06-13 潍坊医学院 Multi-module large/mouse metabolism cage compatible with IVC system

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114711826A (en) * 2022-02-21 2022-07-08 四川大学华西医院 Stool sampling device
CN116250490A (en) * 2023-05-09 2023-06-13 潍坊医学院 Multi-module large/mouse metabolism cage compatible with IVC system

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Application publication date: 20211217

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