CN206253396U - A kind of biochip automated cleaning system - Google Patents

Abstract

A kind of biochip automated cleaning system, lifting two-dimentional machinery arm including workbench, on the workbench and be connected to multiple unit servomotors of the workbench, also including be located on the workbench jointly incubation reaction unit, embathe unit, rinse unit and post-processing unit；Unit servomotor drives rotation as described in one respectively for first rotating disk, second rotating disk, the 3rd rotating disk, the 4th rotating disk；First rotating disk, second rotating disk are also associated with chip shaking device.Originally it is structurally consummate, easy to use utility model, forms one and efficiently, easily automate cleaning line, greatly improve operating efficiency, significantly reduce labor strength, cleaning performance is excellent.

Description

A kind of biochip automated cleaning system

Technical field

The utility model is related to biochip technology field, specifically a kind of biochip automated cleaning system.

Background technology

Biochip, also known as protein chip or genetic chip, they originate from DNA hybridization probe technique and semi-conductor industry The crystallization that technology is combined.The technology mean by a large amount of probe molecules be fixed on holder after with the DNA with fluorescence labeling or Other sample molecules are hybridized, by detecting the hybridization signal intensities of each probe molecule and then obtaining the quantity of sample molecule And sequence information.Current biochip is molded to be formed using transparent material, and upper and lower two unit pieces pressing is buckled, by layer of glass fiber Film is fixed on centre, and in biochemical reaction and processing procedure, biochip is needed by multiples such as incubation reaction, cleaning, fractionations Processing step, and in traditional operation in those steps, substantial amounts of manually operation is required to, pretend the uniformity of industry Difference, and the labour intensity of workman is very big, and general work efficiency is not also high, and input cost can be very big in the long run, with output It is not directly proportional.

Utility model content

Technical purpose of the present utility model is to provide a kind of biochip automated cleaning system, solves traditional operation certainly The problem that dynamicization low degree, inefficiency, labor strength are big, input cost is high.

Concrete technical scheme of the present utility model is as follows：A kind of biochip automated cleaning system, including workbench, set In the lifting two-dimentional machinery arm on the workbench and the multiple unit servomotors for being connected to the workbench, also including common Incubation reaction unit on the workbench, embathe unit, rinse unit and post-processing unit；The incubation reaction unit Chip Container including the first rotating disk, for fixing biochip and it is used to fix the chip on first rotating disk First fixed stop of Container；The unit that embathes is used to be put into and soak including the second rotating disk, on second rotating disk Wash the chip rinsing container of biochip, the second fixed stop for fixing the chip rinsing container and located at the work It is used to open or close the headstock gear of chip rinsing container on platform；The flushing unit includes the 3rd rotating disk, located at described the It is used to fix the 3rd fixed stop of biochip, the flushing framework for rinsing biochip and for installing on three rotating disks State the vertical reciprocating mechanism for rinsing framework and coordinating with the 3rd rotating disk；The post-processing unit include the 4th rotating disk, For inciting somebody to action on the 4th rotating disk for fixing the 4th fixed block plate of the chip Container, on the workbench Base separator and be used for biochip on the workbench that the chip Container with biochip separate The chip detachment apparatus that lower unit piece is separate；The chip Container includes accommodating base, the side on the accommodating base Along retaining wall and the biochip sticking department on the edge retaining wall, formed on the accommodating base and enclosed by the edge retaining wall Into biochip accommodation space；The biochip sticking department is including the locking seat on the edge retaining wall, located at institute State moving horizontally space and be placed in the movable block for moving horizontally spatially in locking seat；The movable block is provided with movement Reduction torsion spring, the locking seat is provided with the fluting positioned at the mobile reduction torsion spring both sides, the two of the mobile reduction torsion spring End is respectively equipped with the extension inserted in two flutings；The movable block tail end is also associated with shank of the key, the shank of the key end Lock nut is provided with, the space that moves horizontally is through to outside the locking seat, and the shank of the key stretches out the locking seat；Described first Unit servomotor drives rotation as described in one respectively for rotating disk, second rotating disk, the 3rd rotating disk, the 4th rotating disk； First rotating disk, second rotating disk are also associated with chip shaking device.

Preferably, the chip rinsing container is including box body, the box mouth located at the box body top, located at the box body The upper connection shaft seat positioned at the box mouth side is provided with moving block with the lid for being connected to the connection shaft seat, the lid, The moving block is provided with the rotating shaft being connected with the connection shaft seat, and the rotating shaft is provided with rotation reduction torsion spring, the rotation Reduction torsion spring is provided with two end extensions for inserting the moving block, the connection shaft seat respectively；The chip embathes appearance Device also includes that the cover lock portion of the box mouth opposite side and the cleaning on the box body are located on the box body to be used Hole group, the connection shaft seat is mutually in the offside on the box body with the cover lock portion；Cleaning hole group includes Washing lotion hand-hole, washing lotion tap and tray interior air pressure tap；The cover lock portion includes being connected to the box body Locking pedestal, the horizontal sliding space on the locking pedestal and the sliding shoe that is placed on the horizontal sliding space； Lock is additionally provided with the lid, the lock coordinates locking with the sliding shoe.The cover lock portion also includes being located at institute The space that is inserted vertically on locking pedestal is stated, the horizontal sliding space converges with the space intersection that is inserted vertically into, the slip Build end be located at it is described be inserted vertically into space, the lock can insert described be inserted vertically into space and the lock is provided with For the latch hooked with the sliding shoe head end bottom surface；The sliding shoe is provided with slip reduction torsion spring, the locking pedestal It is provided with positioned at the side fluting for sliding reduction torsion spring both sides, being respectively arranged at two ends with for reduction torsion spring of slip is inserted described in two Extension in the fluting of side；The sliding shoe front end is provided with for latching the inclined plane for pushing force for described；The sliding shoe Tail end is also associated with pull handle, and the pull handle end is provided with drawing cap, and the horizontal sliding space is through to outside the locking pedestal, The pull handle stretches out the locking pedestal.

Preferably, the headstock gear includes support body, the support body is provided with left plate and right plate, the left plate The cap-opening mechanism for opening cleaning container lid is provided with, the right plate is provided with the conjunction for closing cleaning container lid Lid mechanism；The cap-opening mechanism include uncapping with servomotor, be connected to it is described uncap with servomotor uncap with shaft coupling, Be connected to it is described uncap with shaft coupling uncap with screw mandrel, be connected to it is described uncap with screw mandrel uncap with walking seat and one end connection Uncapped with walking seat and the other end is connected with the uncapping with walking frame of lockaid gun in described；The lockaid gun includes unlocking framework and is located at Hollow aisle in the unlocking framework, the side block wall of the side of the close described right plate of the unlocking framework is provided with and institute State pull handle Ka Dao, the pull handle Ka Dao that hollow aisle communicates and the side block wall is divided into upside retaining wall and downside retaining wall；It is described The inner surface of upside retaining wall and/or the downside retaining wall from one end to the other end gradually in the unlocking framework with the side block wall Relative opposite side retaining wall is inclined；The closing mechanism includes closing lid servomotor, is connected to the closing lid servomotor Closing lid shaft coupling, be connected to the closing lid screw mandrel of the closing lid shaft coupling, be connected to the closing lid of the closing lid screw mandrel With walking seat and one end is connected to the closing lid with walking seat and the other end is connected with the closing lid of gland device with walking frame；The gland device bag Include and be connected to the closing lid mounting bracket and the pinch roller on the mounting bracket for walking frame.

Preferably, the 3rd rotating disk lower section is connected with Rotational Cylindrical, be provided with inside the Rotational Cylindrical rolling bearing and with The central shaft that the rolling bearing coordinates；The vertical reciprocating mechanism includes sequentially passing through the central shaft and the described 3rd The vertical guide rod of rotating disk and for making the vertical guide rod carry out vertical reciprocating vertical guide-bar driving mechanism；The flushing Framework includes being connected to first framework and the second framework of the vertical guide rod, and first framework is provided with first jet, institute State the second framework and be provided with second nozzle.

Preferably, the vertical guide-bar driving mechanism includes vertical guide rod stepper motor, is connected to and described leads vertically The vertical guide rod shaft coupling of bar stepper motor, the vertical guide rod screw mandrel for being connected to the vertical guide rod shaft coupling, company The Mobile base for being connected to the vertical guide rod screw mandrel and the fixed plate for being connected to the Mobile base, the vertical lower end of the guide rod connection In being provided with the linear bearing that coordinates with the vertical guide rod in the fixed plate, the central shaft；First framework includes connecting Be connected to the vertical guide rod be piercing in the 3rd rotating disk top base and the erecting bed on the base, described One nozzle is on the erecting bed；Second framework includes that being connected to the vertical guide rod is piercing in the 3rd rotating disk The support shaft on top, the top board of the support shaft is connected to, the column of the top board is connected to and is connected between the column Installation band, the second nozzle takes located at the installation, and the installation band is suspended in the 3rd rotating disk top.

Preferably, the base separator includes that base separates framework, the base separates framework includes two pieces of bottoms Seat separating side plate separates back plate, the base separating side plate and the base with the base of two pieces of base separating side plates of connection Separate back plate and be collectively forming base separation longitudinal space, the base separates longitudinal space includes upper base lead-in cavity and bottom Base reclaims chamber；The base separates and base guide bar is connected with back plate, the base separating side plate be provided with it is described on The base support that the base guiding channel being interlinked to the outside in portion's base lead-in cavity and the base guiding channel coordinate draw section and with it is described The biochip clamp system and base unlocking mechanism of base guiding channel cooperating, the guide bar are provided with guiding and slide Seat, installing arm is connected with the guiding slide, and the installing arm is provided with base mechanical gripper and for the biological core The clutch of piece clamp system force.

Preferably, the biochip clamp system includes the axle bed being located in the base separating side plate, inserts institute State in axle bed and by the upper base lead-in cavity through the base separating side plate movable axis, be articulated with the movable axis The active lever of the one end outside the base separating side plate, the biochip push rod for being connected to the active lever and fixation It is connected to the base separating side plate and the support shaft being articulated with the middle part of the active lever；The biochip push rod passes through institute State base guiding channel；The base guiding channel is provided with baffle plate, and the biochip push rod passes through the baffle plate, the life The reset spring offseted with the baffle plate is arranged with thing chip push rod；The clutch includes being fixedly connected on the installation Pushing tow main body on arm and it is used for the movable axis from the upper base lead-in cavity to described in the pushing tow main body The extrapolated pushing tow face of base separating side plate；The base unlocking mechanism includes being fixedly connected on the solution of the base separating side plate Lock framework and the hollow aisle in the unblock framework, the unblock framework is near the upper base lead-in cavity side Side wall is provided with the shank of the key Ka Dao, the shank of the key Ka Dao communicated with the hollow aisle and the side wall is divided into upper side wall and downside Wall；The inner surface of the upper side wall and/or the lower wall separates back plate one end near the base by away from the base Back plate one end is separated gradually to be inclined to hollow aisle；The upper side wall is additionally provided with the close described base relative to the lower wall Separate the extension of back plate side；The base support is drawn section and includes being located at institute respectively located at the base separating side plate inner surface State the epimere and hypomere of the upper and lower both sides of base guiding channel；The epimere is provided with the close described base relative to the hypomere Separate the lengthening section of back plate side, the lengthening section is provided with base and squeezes cuts somebody's hair；The installing arm is externally connected with haulage gear, institute State haulage gear including power for traction machine, be connected to the power for traction machine traction shaft coupling, be connected to it is described traction use The traction screw mandrel of shaft coupling, the connecting seat for being connected to the traction screw mandrel and one are connected to the connecting seat and other end It is connected to the transmission bridge of the installing arm.

Preferably, the chip detachment apparatus include transmission motor, are connected to the driving tooth of the transmission motor Wheel, for the driven gear with the driving gear synchronous axial system and it is connected the transmission of the driving gear and the driven gear Band；The chip detachment apparatus also include chip separator frame, are grabbed for biochip to be sent into the first of the chip separator frame Take mechanism and coordinate first grasping mechanism to be used to clamp the second grasping mechanism of unit piece on biochip and for will be raw The detachment means that lower unit piece is separate on thing chip, the detachment means and first grasping mechanism are commonly connected to the biography Dynamic band；After the chip separator frame includes that the chip of two pieces of chip separating side plates of two chips separating side plate and connection is separated Plate, the chip separation back plate together form chip and separates longitudinal space with the chip separating side plate, and the chip is separated Longitudinal space includes the upper core for first grasping mechanism, second grasping mechanism and the detachment means cooperating Piece lead-in cavity and the lower chips recovery chamber for housing unit piece on biochip.

Preferably, the detachment means include being connected to the drive link of the transmission belt, are connected to the drive link Connecting rod, the first transmission group driven by the drive link and the second transmission group driven by first transmission group；The company Extension bar is provided with driving cog；First transmission group include being respectively arranged on the first axle bed in two chip separating side plates, Insert two first axle beds and through the upper chip lead-in cavity first rotating shaft and be connected to the first rotating shaft two The first gear at end, one of them described first gear is connected with driving cog engagement；Second transmission group includes difference The second axle bed in two chip separating side plates, it is respectively implanted two second axle beds and stretches into the upper core Second rotating shaft of piece lead-in cavity, the chip sled block for being connected to the one end of second rotating shaft in the upper chip lead-in cavity With the second gear for being connected to the second rotating shaft other end, the engagement of the second gear and the first gear is connected；It is described The rotating shaft back-moving spring between second axle bed and the second gear is additionally provided with second rotating shaft；First crawl Mechanism includes chip mechanical gripper, the linking arm for being connected to the chip mechanical gripper and the transmission for driving the linking arm Arm, the transmission arm is connected to the transmission belt simultaneously；Second grasping mechanism includes being separated in back plate located at the chip Pedestal, be connected to the pull bar of the pedestal, be articulated with two pieces of the deflection respectively chip separating side plate of the pull bar head end Two poles and be hingedly connected to two two chips clamping plates of the pole；The chip clamping plate is slidably connected jointly leads Bar, the guide rod two ends are fixedly connected on the chip separating side plate, be arranged with the guide rod positioned at the chip clamping plate it Between clamping plate back-moving spring.

Preferably, the chip shaking device includes chassis and telophragma, the chassis is connected to the unit servo Motor and driven by the unit servomotor, the telophragma is located at the chassis and first rotating disk/described second turn Between disk, be provided with multiple the first connectors for supporting between the chassis and the telophragma, the telophragma with it is described Multiple is provided between first rotating disk/second rotating disk for supporting and makes eccentric turn of first rotating disk/second rotating disk The second dynamic connector, one of them described second connector is connected with lead agency；First connector includes being connected to The upper pedestal of the telophragma, it is connected to the lower base on the chassis and is connected between the upper pedestal and the lower base Breeze way；Second connector includes being fixedly connected on the upper axle bed of first rotating disk/second rotating disk, is fixedly connected In the lower axle bed and the rotor for being rotationally connected with the upper axle bed and the lower axle bed simultaneously of the telophragma；The rotor The upper connecting shaft being connected is rotated with the upper axle bed and located at the main body including main body block, located at the main body block upper surface Block lower surface and the lower connecting shaft being connected is rotated with the lower axle bed, the axial line of the upper connecting shaft and the lower connecting shaft Axial line is not on the same line；The lead agency includes the drive motor and the drive motor on the chassis The belt pulley of drive connection and the wheel shaft being connected with the belt pulley, the wheel shaft are consolidated with the lower connecting shaft of second connector Connect or be integrally formed calmly.

Technological merit of the present utility model is that the biochip automated cleaning system is structurally consummate, easy to use, Form one and efficiently, easily automate cleaning line, greatly improve operating efficiency, significantly reduce labor strength, clearly Wash excellent effect.

Brief description of the drawings

Fig. 1 is the overall structure diagram of the utility model embodiment；

Fig. 2 is the structural representation of the chip Container；

Fig. 3 is the structural representation of β in Fig. 2；

Fig. 4 is the structural representation of the chip shaking device；

Fig. 5 is the partial structural diagram of the chip shaking device；

Fig. 6 is the positive structure schematic of the chip rinsing container；

Fig. 7 is the structure schematic diagram of the chip rinsing container；

Fig. 8 is the partial structural diagram of the box body；

Fig. 9 is the structural representation of α parts in Fig. 6；

Figure 10 is a side-looking viewing angle constructions schematic diagram of the headstock gear；

Figure 11 is that the opposite side of the headstock gear regards viewing angle constructions schematic diagram；

Figure 12 is the partial structural diagram of the headstock gear；

Figure 13 is the cross-sectional view of the chip flusher；

Figure 14 is the structural representation at a side-looking visual angle of the base separator；

Figure 15 is the partial structural diagram of the base separator；

Figure 16 is the partial structural diagram of the base separator；

Figure 17 is a side-looking viewing angle constructions schematic diagram of the chip detachment apparatus；

Figure 18 is that the opposite side of the chip detachment apparatus regards viewing angle constructions schematic diagram；

Figure 19 is portion's partial structural diagram of the chip detachment apparatus；

Corresponding each toponym is numbered in figure to be respectively：The rotating disks of A10- first, the fixed stops of A101- first, B30- cores Piece separator frame, B301- chip separating side plates, B3011- slideways, the upper position blocks of B3012-, position block under B3013-, B3014- release links, B3015- back-moving springs, B3016- slideways, B302- chips separate back plate, and B303- chips separate foreboard, B304- connecting rods, B3041- drive links, B30411- driving cogs, the axle beds of B3042- first, B3043- first rotating shafts, B3044- One gear, the axle beds of B3045- second, the rotating shafts of B3046- second, B3047- chips sled block, B3048- second gears, B305- chips Mechanical gripper, B3051- linking arms, B3052- transmission arms, B3053- substrates, B3054- substrates, B3055- positive stops, B306- Pedestal, B3061- pull bars, B3062- poles, B3063- chip clamping plates, B3064- guide rods, B3065- springs, the guiding of B307- upper half Cell body, the upper reset baffle blocks of B3071-, B308- lower half guiding cell body, reset baffle block under B3081-；The rotating disks of B10- the 4th, B10- Four fixed stops, B20- bases separation framework, B201- base separating side plates, B2011- base guiding channels, B2012- axle beds, B2013- movable axis, B2014- active levers, B2015- biochip push rods, B2016- support shafts, B2017- unblock frameworks, The hollow aisle of B20171-, B20172- base shank of the key Ka Dao, B20173- upper side walls, B20174- lower walls, B2018- base supports Draw section, B20181- epimeres, B20182- hypomeres, B20183- bases are squeezed and cut somebody's hair, B202- bases separate back plate, B203- bases point From foreboard, B204- base guide bars, B2041- installing arms, B2042- base mechanical grippers, B2043- pushing tow main bodys, B2044- Pushing tow face, B2045- guiding slides, B205- power for traction machines, B2051- traction screw mandrels, B2052- traction connecting seats, B2053- is driven bridge；The rotating disks of C10- the 3rd, the fixed stops of C101- the 3rd, the vertical guide channel of C1011- biochips, C102- Osculum, C20- rotary units, C201- Rotational Cylindricals, C202- rolling bearings, C203- central shafts, C207- ring flanges, C30- is erected Straight to move back and forth unit, the vertical guide rod stepper motors of C301-, the vertical guide rod shaft couplings of C302-, the vertical guide rods of C303- are used Screw mandrel, C304- fixed plates, the vertical guide rods of C305-, C306- Mobile bases, C40- rinses unit, and C401- bases, C402- is installed Platform, C403- support shafts, C404- top boards, C405- columns, C406- installation bands, C407- first jets, C408- second nozzles, C50- supporting platens；The rotating disks of D10- second, the fixed stops of D101- second, D20- support bodys, D201- left plates, D202- right plates, D203- uncaps and uses servomotor, and D2031- uncaps and uses shaft coupling, and D2032- uncaps and uses screw mandrel, and D2033- uncaps with walking seat, D2034- uncaps with walking frame, D2035- unlocking frameworks, the hollow aisle of D20351-, D20352- pull handles Ka Dao, D20353- upside Wall, D20354- lower walls, D204- closing lid servomotors, D2041- closing lid shaft couplings, D2042- closing lid screw mandrels, D2043- closing lids incline installing plate with seat, D2044- closing lids is walked with frame, D2045- mounting brackets, D2046- pinch rollers, D2047- is walked, D2048- sides pushing block, D2049- pushes the ball side face；B1- houses base, b11- putting grooves, b2- edges retaining wall, b21- locking seats, B211- slots, b212- spacing preiections, b22- movable blocks, b221- masts, and b222- biochips compress end block, and b223- is biological Chip accepts inclined plane, b23- movement reduction torsion springs, b24- movement limited blocks, b3- biochips sealing heelpiece, b4- elasticity branch Support body, b5- metallic gaskets；D1- box bodys, d11- biochips importing holder, d12- rotary spacing blocks, d13- washing lotion hand-holes, D14- washing lotion taps, d15- tray interior air pressure taps, d2- lids, d21- moving blocks, d211- rotating shafts, d22- locks, D221- latches, d23- sealing rings, d24- biochip compact heaps, d3- connection shaft seats, d4- locking pedestals, d41- sides fluting, D5- sliding shoes, d51- slides reduction torsion spring, and d52- cylinders, d53- slides limited block, d54- inclined planes；E1- chassis, in the middle of e2- Disk, the connectors of e3- first, e31- upper pedestals, e32- lower bases, e33- breeze ways, the connectors of e4- second, the upper axle beds of e41-, Axle bed under e42-, e43- main body blocks, the upper connecting shafts of e431-, connecting shaft under e432-, e44- centrifugal-blocks, e5- drive motors, e51- Belt pulley, e52- wheel shafts.

Specific embodiment

Below in conjunction with accompanying drawing, by specific embodiment, the utility model is described in further detail：See Fig. 1, it is a kind of biological Chip automated cleaning system, including workbench, located at worktable lifting two-dimentional machinery arm and be connected to workbench multiple it is single First servomotor, also including the common incubation reaction unit being located on workbench, embathes unit, rinses unit and post-processes list Unit；Incubation reaction unit includes the first rotating disk A10, the chip Container for fixing biochip and located at the first rotating disk A10 Upper the first fixed stop A101 for being used for fixed chip Container；Unit is embathed including the second rotating disk D10, located at the second rotating disk It is used to be put into and embathe the chip rinsing container of biochip, the second fixed stop for fixed chip rinsing container on D10 D101 and it is used to open or close the headstock gear of chip rinsing container on workbench；Rinsing unit includes the 3rd rotating disk C10, on the 3rd rotating disk C10 be used for fix the 3rd fixed stop C101 of biochip, for rinsing rushing for biochip Wash framework C40 and for install rinse framework C40 and with the 3rd rotating disk C10 coordinate vertical reciprocating mechanism C30；Post processing Unit includes the 4th rotating disk B10, the 4th fixed block plate B101 on the 4th rotating disk B10 for fixed chip Container, sets Being used in the base separator for being used to separate chip Container with biochip on workbench and on workbench will be raw The chip detachment apparatus that lower unit piece is separate on thing chip；First fixed stop A101, the second fixed stop D101, the 3rd fix Block C101, the 4th fixed stop B101 each can be set multiple, and each self-forming fixed space can be set adjustment on each block The plunger of dynamics, for holding out against chip Container or chip rinsing container or biochip, plays a part of equivalent to fixture.

See Fig. 2, Fig. 3, chip Container includes accommodating base b1, the edge retaining wall b2 on accommodating base b1 and is located at Biochip sticking department on edge retaining wall b2, forms the accommodating sky of biochip surrounded by edge retaining wall b2 on accommodating base b1 Between, biochip sealing heelpiece b3 is provided with biochip accommodation space；Biochip sticking department is included located at edge retaining wall b2 On locking seat b21, moving horizontally space and be placed in the movable block b22 for moving horizontally spatially on locking seat b21；Move Motion block b22 is provided with mobile reduction torsion spring b23, and locking seat b21 is provided with the fluting positioned at mobile reduction torsion spring b23 both sides B211, mobile reduction torsion spring b23's is respectively arranged at two ends with the extension inserted in two fluting b211.Movable block b22 is provided with For the mast b221 being fixed by socket for mobile reduction torsion spring b23, can also be set on mast b221 prevents from moving reduction torsion spring The cap body of b23 abjections.The inwall of fluting b211 is provided with relative spacing preiection b212, is formed for prolonging between spacing preiection b212 The passageway that section long is inserted.Movable block b22 front ends are provided with biochip and compress end block b222, and the biochip that can be put into is pressed in life On thing chip sealing heelpiece b3.Biochip compresses end block b222 tops and is provided with biochip undertaking inclined plane b223, Neng Goujie Firmly towards biochip accommodation space decentralization biochip, while because the design on its inclined-plane receive movable block b22 is outside The thrust of the horizontal direction of release, movable block b22 is outwards pushed open with this, and movable block b22 passes through mobile reduction torsion spring b23 and resets Biochip is firmly fixed afterwards.Movable block b22 tail ends are also associated with shank of the key, and shank of the key end is provided with lock nut, moves horizontally Space is through to outside locking seat b21, and shank of the key stretches out locking seat b21.Movable block b22 tail ends can also connect mobile limited block b24, Shank of the key moves horizontally space and is through to outside locking seat b21 also cross limited block b24 is moved, and moves limited block b24 positions all the time Can offset in locking seat b21 outsides and with locking seat b21 outer surfaces, so as to limit the ultimate range that movable block b22 is moved inward, Avoid excessive interpolation and generation problem.

First rotating disk A10, the second rotating disk D10, the 3rd rotating disk C10, the 4th rotating disk B10 are driven by unit servomotor respectively Rotate；First rotating disk A10, the second rotating disk D10 are also associated with chip shaking device.Incubation reaction needs biochip in regulation temperature Carry out internal biochemical reaction under degree, it is necessary to stand and rock two states mutual cooperation, and cleaning afterwards be also required to rock with Biochip is allowed fully to be cleaned in cleaning container.

See Fig. 4, Fig. 5, chip shaking device include chassis e1 and telophragma e2, chassis e1 be connected to unit servomotor and Driven by unit servomotor, telophragma e2 is located between chassis e1 and first the second rotating disks of rotating disk A10/ D10, and chassis e1 is with Be provided between disk e2 it is multiple for the first connector e3, telophragma e2 and first the second rotating disks of rotating disk A10/ D10 that support it Between be provided with multiple for supporting and making the second connector e4 of first rotating disk A10/ the second rotating disk D10 eccentric rotaries, one of them Second connector e4 is connected with lead agency, and chassis e1 is connected to unit servomotor and is driven by unit servomotor；First Connector e3 includes being connected to the upper pedestal e31 of telophragma e2, is connected to the lower base e32 of chassis e1 and is connected to upper pedestal Breeze way e33 between e31 and lower base e32, breeze way may be selected rubber, plastic or other material；Second connector e4 includes solid Surely the upper axle bed e41 that is connected to first the second rotating disks of rotating disk A10/ D10, the lower axle bed e42 for being fixedly connected on telophragma e2 and same When be rotationally connected with the rotor of axle bed e41 and lower axle bed e42；Rotor is including main body block e43, on main body block e43 Surface and with upper axle bed e41 rotate the upper connecting shaft e431 that be connected and located at main body block e43 lower surfaces and with lower axle bed e42 rotations The lower connecting shaft e432 of connection, the axial line of the axial line of upper connecting shaft e431 and lower connecting shaft e432 not on the same line, Main body block e43 can be a cylinder；Lead agency includes that drive motor e5 and drive motor the e5 transmission on the e1 of chassis connect The lower connecting shaft e432 of the belt pulley e51 for the connecing and wheel shaft e52 being connected with belt pulley e51, wheel shaft e52 and the second connector e4 consolidates Connect or be integrally formed calmly.Centrifugal-block e44, the center of gravity of centrifugal-block e44 and the center of gravity of main body block e43 are additionally provided with main body block e43 It is mutually misaligned.Centrifugal-block e44 is actual it can also be provided that the bigger main body block e43 of volume.Accompanying drawing middle belt pulley e51 and drive electricity The belt of the connection of machine e5 is omitted and is not drawn into.

In real work, servomotor drives first the second rotating disks of rotating disk A10/ D10, telophragma e2, chassis e1 to be constituted Integral-rotation, drive motor e5 drives wherein the second connector e3 actions, and remaining second connector e3 is driven, on rotor Eccentric structure is upper connecting shaft e431, lower connecting shaft e432 so that first the second rotating disks of rotating disk A10/ D10 is same in the horizontal direction When make a swing for certain amplitude so that the placement thing on first the second rotating disks of rotating disk A10/ D10 is waved, simulation Artificial rocking action.The presence of centrifugal-block e44 can cause that rotor is whole can have a centrifugal force in rotation process, to people For the simulation degree of rocking action is higher, centrifugal-block e44 generally need to only set one.

See Fig. 6, Fig. 7, Fig. 8, Fig. 9, chip rinsing container is including box body d1, the box mouth located at box body d1 tops, located at box Positioned at the connection shaft seat d3 and the lid d2 for being connected to connection shaft seat d3 of box mouth side on body d1, lid d2 is provided with moving block D21, moving block d21 are provided with the rotating shaft d211 being connected with connection shaft seat d3, and rotating shaft d211 is provided with rotation reduction torsion spring, rotate Reduction torsion spring is provided with insertion moving block d21, two end extensions of connection shaft seat d3 respectively, and rotating reduction torsion spring can make lid Body d2 automatic stabilisations when not covering are remained on, at the same box body d1 be provided with for moving block d21 coordinate and with this Limit the maximum rotary spacing block d12 for opening radius of lid d2；The sealing ring d23 matched with box mouth is additionally provided with lid d2, is protected The cleaning sealing of card box body d1；Biochip compact heap d24 is additionally provided with lid d2；Life is additionally provided with box body d1 internal side walls Thing chip imports holder d11, is capable of the position of auxiliary reception fixation biochip, and biochip imports holder d11 includes holder Body and the jig arm located at clipping base two ends, are provided with biochip and import space between jig arm.Chip rinsing container also includes being located at Positioned at the cover lock portion of box mouth opposite side and the hole group of the cleaning on box body d1, connection shaft seat d3 and lid on box body d1 Sticking department is mutually in the offside on box body d1；Cleaning includes washing lotion hand-hole d13, washing lotion tap d14 and box with hole group Body air pressure inside tap d15, can the existing apparatus such as external flow pump, flexible pipe, negative pressure pump.Cover lock portion includes being connected to box The locking pedestal d4 of body d1, the horizontal sliding space on locking pedestal d4 and the sliding shoe being placed on horizontal sliding space d5；Lock d22, lock d22 and sliding shoe d5 are additionally provided with lid d2 and coordinate locking.Cover lock portion is also included located at locking base Space is inserted vertically on seat d4, space is inserted vertically into and be may be selected, longitudinally through locking pedestal d4, to be easy to the lock on lid d2 D22 is accessible to insert.Horizontal sliding space converges with space intersection is inserted vertically into, and sliding shoe d5 head ends are located at and are inserted vertically into space In, lock d22 can be inserted and is inserted vertically into space and latch d22 and be provided with latch for being hooked with sliding shoe d5 head ends bottom surface d221；Lock d22 is inserted when being inserted vertically into space, and sliding shoe d5 is in normal static condition and sliding shoe d5 head ends gear is in lock Detain on the placing direction of d22, now pull out sliding shoe d5, stepped down to lock d22, while latch d22 to continue to put completely Enter to be inserted vertically into space, then sliding shoe d5 back push and sliding shoe d5 bottom surface and lock d22 latch d221 phases To conjunction, lock d22 is prevented to exit.Sliding shoe d5 is provided with slip reduction torsion spring d51, and locking pedestal d4 is provided with multiple positioned at sliding The side fluting d41 of position torsion spring d51 both sides, slides being respectively arranged at two ends with for reduction torsion spring d51 and inserts prolonging in two sides flutings d41 Stretch section；Sliding shoe d5 front ends are provided with the inclined plane d54 for pushing force for lock d22, due to the presence of inclined plane d54, lock Button d22 is inserted and inclined plane d54 can be pressed to when being inserted vertically into space, so as to produce the component of horizontal direction to sliding shoe d5 so that Sliding shoe d5 can be pressurized and exit automatic resigning.Sliding shoe d5 is provided with for for sliding the cylinder that reduction torsion spring d51 is fixed by socket D52, can be set the cap body of anti-sliding stop back-moving spring d51 abjections on cylinder d52；Sliding shoe d5 tail ends are also associated with pull handle, draw Pommel portion is provided with drawing cap, and horizontal sliding space is through to outside locking pedestal d4, and pull handle stretches out locking pedestal d4.Sliding shoe d5 tails End is also associated with sliding limited block d53, and pull handle is through to outside locking pedestal d4 also cross limited block d53, sliding space is slided Portion, slides limited block d53 and is always positioned at locking pedestal d4 outsides and can be offseted with locking pedestal d4 outer surfaces, so as to limit slip The ultimate range of block d5 slid inwards, it is to avoid excessive interpolation and produce problem.

See Figure 10, Figure 11, Figure 12, headstock gear includes that support body D20, support body D20 are provided with left plate D201 and right plate D202, left plate D201 are provided with the cap-opening mechanism for opening cleaning container lid d2, and right plate D202 is provided with for closing Close the closing mechanism of cleaning container lid d2；Cap-opening mechanism includes uncapping with servomotor D203, is connected to and uncaps with servo electricity Machine D203's uncaps with shaft coupling D2031, is connected to and uncaps with the uncapping with screw mandrel D2032 of shaft coupling D2031, be connected to and uncap With uncapping with walking a D2033 and one end is connected to and uncaps with walking a D2033 and the other end is connected with lockaid gun for screw mandrel D2032 Uncap with walking frame D2034；Lockaid gun includes the unlocking framework D2035 and hollow aisle D20351 in unlocking framework D2035, The side block wall of the side of the close right plate D202 of unlocking framework D2035 is provided with the pull handle card communicated with hollow aisle D20351 The side block wall is divided into upside retaining wall D20353 with downside retaining wall D20354 by road D20352, pull handle card road D20352；Upper side block The inner surface of wall D20353 and/or downside retaining wall D20354 from one end to the other end gradually on unlocking framework D2035 with the side The relative opposite side retaining wall of retaining wall is inclined；Closing mechanism includes closing lid servomotor D204, is connected to closing lid servomotor The closing lid shaft coupling D2041 of D204, the closing lid screw mandrel D2042 for being connected to closing lid shaft coupling D2041, be connected to closing lid use The closing lid of screw mandrel D2042 is with walking a D2043 and one end is connected to closing lid with walking a D2043 and the other end is connected with the conjunction of gland device Lid is with walking frame D2044；Gland device includes being connected to closing lid with the mounting bracket D2045 for walking frame D2044 and on mounting bracket D2045 Pinch roller D2046.Mounting bracket D2045 is provided with inclination installing plate D2047, pinch roller D2046 on inclination installing plate D2047. The side pushing block D2048 for lateral pushing tow cleaning container lid is additionally provided with mounting bracket D2045.Side pushing block D2048 is provided with side Push the ball face D2049.In some cases, the position of lid d2 inclination openings state is likely difficult to effectively be contacted with pinch roller D2046, this When side pushing block D2048 rotating disk can be coordinated to rotate laterally elapse to appropriate location lid d2, to enable pinch roller D2046 suitable Profit contact simultaneously pushes lid d2.

In real work, cleaning container is fixed on the second rotating disk D10, can be stopped when appropriate location is gone to, and is uncapped with watching Motor D203 startups are taken, is finally uncapped and can move to the second rotating disk D10 with walking frame D2034, drive the synchronous shiftings of unlocking framework D2035 It is dynamic, during the pull handle of cleaning container can snap in pull handle card road D20352 afterwards, the drawing cap of pull handle end can with upside retaining wall D20353, The inner surface of the inner surface laminating of downside retaining wall D20354, upside retaining wall D20353 and/or downside retaining wall D20354 by one end extremely The other end is gradually inclined to opposite side retaining wall relative with the side block wall on unlocking framework D2035, herein " one end is to another End " be by cleaning container direction or the second rotating disk D10 directions to support body D20 directions, with cause pull handle with pull handle Ka Dao In the relative motion of D20352, cap is drawn gradually to be drawn by the inclined inner surface of upside retaining wall D20353 and/or downside retaining wall D20354 Dynamic, pull handle is drawn out therewith so that sliding shoe d5 is no longer fixed with the lock d22 phases on lid d2, and lid d2 is immediately because rotating Reduction torsion spring and be in open mode；Then, biochip is put into cleaning container, closing lid is started with servomotor D204, Final closing lid can be moved with a D2043 is walked to the second rotating disk D10 directions, drive mounting bracket D2045 synchronizing movings, pinch roller D2046 The contact lid d2 back sides at a slant, and the lid d2 pressures that will gradually open are until cover.Uncap with walking frame D2034 and conjunction Lid can be made up of with frame D2044 is walked the connection of multiple connecting rods.

See that Figure 13, the 3rd fixed stop C101 are arranged to vertical block in pairs, between the 3rd fixed stop C101 Biochip placement space is formed, the 3rd fixed stop C101 is provided with the vertical guide channel C1011 of biochip, in order to give birth to Thing chip is accurately stably inserted, and biochip is placed between two the 3rd fixed stop C101 by card；3rd rotating disk C10 lower sections Rotational Cylindrical C201 is connected with, rolling bearing C202 and the central shaft coordinated with rolling bearing C202 are provided with inside Rotational Cylindrical C201 C203, central shaft C203 lower section are connected with ring flange C207, ring flange C207 and servomotor C205 and are located at supporting platen C50 On, the rolling bearing C202 outside central shaft C203 can use angular contact bearing；Vertical reciprocating mechanism C30 is included successively Through the vertical guide rod C305 of central shaft C203 and the 3rd rotating disk C10 and for making vertical guide rod C305 be moved back and forth vertically Vertical guide-bar driving mechanism；Rinsing framework C40 includes being connected to first framework and the second framework of vertical guide rod C305, first Framework is provided with first jet C407, and the second framework is provided with second nozzle C408.Vertical guide-bar driving mechanism includes leading vertically Bar stepper motor C301, the vertical guide rod shaft coupling C302 for being connected to vertical guide rod stepper motor C301, be connected to it is perpendicular The vertical guide rod screw mandrel C303 of straight guide rod shaft coupling C302, the Mobile base C306 for being connected to vertical guide rod screw mandrel C303 and The fixed plate C304 of Mobile base C306 is connected to, vertical guide rod C305 lower ends are connected to fixed plate C304, are set in central shaft C203 There is the linear bearing coordinated with vertical guide rod C305；First framework includes that being connected to vertical guide rod C305 is piercing in the 3rd rotating disk The base C401 on the top of C10 and the erecting bed C402 on base C401, first jet C407 are on erecting bed C402； Second framework include be connected to vertical guide rod C305 be piercing in the 3rd rotating disk C10 top support shaft C403, be connected to support The top board C404 of axle C403, the column C405 for being connected to top board C404 and the installation band C406 being connected between column C405, the Two nozzle C408 install band C406 and are suspended in the 3rd rotating disk C10 tops located at installing on band C406.First jet C407 and second Nozzle C408 can external delivery hose.Osculum C102 is additionally provided with 3rd rotating disk C10.Vertical guide rod C305 and support shaft Between C403, support shaft C403 and top board C404, between top board C404 and column C405, between column C405 and installation band C406 Each can be connected by screw bolts mode to be connected, realize being mutually permanently connected.Unit servomotor and Rotational Cylindrical C201 The 3rd rotating disk C10 is driven to rotate, it is vertical that vertical guide rod stepper motor C301 and vertical guide rod screw mandrel C303 drives Guide rod C305 carries out pumping for vertical direction；The vertically movable rotation with the 3rd rotating disk C10 of vertical guide rod C305 Motion is separate, is combined by above two motion, each position of biochip can by first jet C407 and Second nozzle C408 is rinsed, and realizing cleaning the Omnibearing automatic of biochip, and rinse unit to stop In the case of with pre-washing function, the effect to the centrifuge dripping of biochip is realized using turntable rotation.

See Figure 14, Figure 15, Figure 16, base separator includes that base separates framework B20, and base separates framework B20 to be included Two pieces of base separating side plate B201, bases of two pieces of base separating side plate B201 of connection separate back plate B202 and base separation foreboard B203, base separating side plate B201 and base separate back plate B202, base separation foreboard B203 and are collectively forming base and separate longitudinal direction Space, base separates longitudinal space includes that upper base lead-in cavity and lower base reclaim chamber；Upper base lead-in cavity and bottom Base reclaims chamber and can separate foreboard B203 by base to define, and base separates foreboard B203 and back plate B202 phases are separated with base Right, base separates foreboard B203 and separates back plate B202 less than base, and reclaim chamber equivalent to lower base separates foreboard by base B203, base separate back plate B202 and base separating side plate B201 and surround, and upper base lead-in cavity separates back plate by base B202 and base separating side plate B201 are surrounded, upper base lead-in cavity do not have base separate foreboard B203 stop and with extraneous phase It is logical；Base separates and base guide bar B204, base guide bar B204 from the extension of upper base lead-in cavity is connected with back plate B202 Back plate B202 is separated to exterior space, i.e. base guide bar B204 perpendicular to base to set, base separating side plate B201 is provided with The base support coordinated with the base guiding channel B2011 and base guiding channel B2011 being interlinked to the outside in upper base lead-in cavity is drawn Section B2018 and biochip clamp system and base unlocking mechanism with base guiding channel B2011 cooperatings, base guiding Bar B204 is provided with guiding slide B2045, and installing arm B2041 is connected with guiding slide B2045, and installing arm B2041 is provided with Base mechanical gripper B2042 and the clutch for being exerted a force to the tight mechanism of biological chip gripper.Base mechanical gripper B2042 will be housed Base b1 is grabbed and is sent to base support and draws on section B2018, is entered in upper base lead-in cavity along base guiding channel B2011, linkage Device can drive biochip clamp system to realize holding out against clamping to biochip.Installing arm B2041 is externally connected with haulage gear, Haulage gear include power for traction machine B205, be connected to power for traction machine B205 traction shaft coupling, be connected to traction join The traction screw mandrel B2051 of axle device, it is connected to the connecting seat B2052 of traction screw mandrel B2051 and one is connected to connecting seat B2052 and other end are connected to the transmission bridge B2053 of installing arm B2041.

Biochip clamp system includes the axle bed B2012 being located on base separating side plate B201, inserts in axle bed B2012 And by upper base lead-in cavity through base separating side plate B201 movable axis B2013, be articulated with movable axis B2013 the bottom of positioned at The active lever B2014 of the one end outside seat separating side plate B201, the biochip push rod B2015 for being connected to active lever B2014 With the support shaft B2016 for being fixedly connected on base separating side plate B201 and being articulated with the middle part of active lever B2014；Biochip top Bar B2015 passes through base guiding channel B2011；Base guiding channel B2011 is provided with baffle plate, and biochip push rod B2015 wears Baffle plate is crossed, the reset spring offseted with baffle plate is arranged with biochip push rod B2015；Movable axis B2013, active lever B2014, biochip push rod B2015, support shaft B2016 utilize lever principle, when movable axis B2013 outside side plate to acting, Active lever B2014 stress and the rotation of certain angle is done around support shaft B2016 so that biochip push rod B2015 Moved to upper base lead-in cavity in company with by base guiding channel B2011, and withstand the biochip being located therein.Support shaft B2016 can be fixed by being fixedly connected on fixed seat, the fixed plate etc. of base separating side plate B201.Clutch includes fixing The pushing tow main body B2043 that is connected on installing arm B2041 and be used on pushing tow main body B2043 by movable axis B2013 by Portion's base lead-in cavity is to base separating side plate B201 extrapolated pushing tow face B2044；Pushing tow face B2044 is contradicted to movable axis B2013 one ends, movable axis B2013 is pushed out, so that the lever principle of aforementioned biological chip clamp system comes into force.

Base unlocking mechanism includes being fixedly connected on the unblock framework B2017 of base separating side plate B201 and located at unblock frame The side wall of hollow aisle B20171 in body B2017, unblock framework B2017 near upper base lead-in cavity side is provided with The side wall is divided into upper side wall B20173 with by the shank of the key card road B20172 that empty aisle B20171 is communicated, shank of the key card road B20172 Side wall B20174；The inner surface of upper side wall B20173 and/or lower wall B20174 separates back plate B202 one end extremely by away from base Back plate B202 one end is separated near base gradually to be inclined to hollow aisle B20171；So cause that shank of the key is snapping in shank of the key Ka Dao After B20172, due to upper side wall B20173, the presence of the inclined inner surface of lower wall B20174, accommodating base b1 is got over to base point From back plate B202 movements, shank of the key is just pulled outward, and final shank of the key is thoroughly drawn together with the movable block b22 that press against biochip Go out, do not relock biochip, biochip is clamped by biochip clamp system, accommodating base b1 is then separated.Upper side wall The close base that B20173 is additionally provided with relative to lower wall B20174 separates the extension of back plate B202 sides；In accommodating base b1 Shank of the key when being fully withdrawn, will not be blocked because of lower wall B20174, can then enable entirely to house base b1 smoothly Fall into lower base reclaim chamber in.Base support is drawn section B2018 and includes being located at respectively located at base separating side plate B201 inner surfaces The epimere B20181 and hypomere B20182 of the upper and lower both sides of base guiding channel B2011；Epimere B20181 is provided with relative to hypomere The close base of B20182 separates the lengthening section of back plate B202 sides, and lengthening section is provided with base and squeezes the B20183 that cuts somebody's hair；Squeeze and cut somebody's hair B2018 touches accommodating base b1 and extrudes it force, accommodating base b1 is smoothly taken off and falls into lower base time In receipts chamber.

See Figure 17, Figure 18, Figure 19, chip detachment apparatus include transmission motor, are connected to the driving tooth of transmission motor Wheel, for the driven gear with driving gear synchronous axial system and it is connected the transmission belt of driving gear and driven gear；Chip is separated Device also includes chip separator frame B30, the first grasping mechanism for biochip to be sent into chip separator frame and cooperation first Grasping mechanism is used to clamp the second grasping mechanism of unit piece on biochip and for lower unit piece on biochip to be separated Detachment means, detachment means and the first grasping mechanism are commonly connected to transmission belt；Chip separator frame B30 includes two chips point Back plate B302 is separated with the chip of connection two chips separating side plate B301 from side plate B301, chip separates back plate B302 and chip Separating side plate B301 together form chip and separate longitudinal space, and chip separates longitudinal space to be included for the first grasping mechanism, the The upper chip lead-in cavity and the bottom for housing unit piece on biochip of two grasping mechanisms and detachment means cooperating Chip reclaims chamber.It is also associated with separating the relative chips of back plate B302 with chip between chip separating side plate B301 and separates foreboard B303, upper chip lead-in cavity and lower chips reclaim chamber can be by being connected to two pieces of side plate B301 and relative with back plate B302 Foreboard B303 is bound.Detachment means include being connected to the drive link B304 of transmission belt, being connected to the connection of drive link B304 Bar B3041, the first transmission group driven by drive link B304 and the second transmission group driven by the first transmission group；Connecting rod B3041 is provided with driving cog B30411；First transmission group includes the first axle being respectively arranged on two chip separating side plate B301 Seat B3042, insert two the first axle bed B3042 and through upper chip lead-in cavity first rotating shaft B3043 and be connected to first First gear B3044, one of first gear B3044 and driving cog the B30411 engagement at rotating shaft B3043 two ends are connected, namely First rotating shaft B3043 is provided with two first gears through the two ends of two chip separating side plate B301 and first rotating shaft B3043 B3044；Second transmission group includes the second axle bed B3045 being respectively arranged on two chip separating side plate B301, is respectively implanted two Individual second axle bed B3045 simultaneously stretches into the second rotating shaft B3046 of upper chip lead-in cavity, is connected to the second rotating shaft B3046 positioned at upper The chip sled block B3047 and the second gear for being connected to the second rotating shaft B3046 other ends of the one end in portion's chip lead-in cavity B3048, second gear B3048 and first gear B3044 engagement are connected, namely the second rotating shaft B3046 is provided with 2, and each second Rotating shaft B3046 one end is stretched into upper chip lead-in cavity through a chip separating side plate B301, also just there is 2 chip sled blocks B3047 pries open the upper lower unit piece of biochip simultaneously in the right and left simultaneously；It is additionally provided with positioned at second on second rotating shaft B3046 Rotating shaft back-moving spring B30461 between axle bed B3045 and second gear B3048；Second rotating shaft B3046 leads positioned at upper chip Draw the one end outside chamber and be additionally provided with push handle B3049, push handle B3049 is provided with multi-directional ball B30491；Set on chip separating side plate B301 There is shifting chute B3011, mobile bar B30111 is interspersed with shifting chute B3011, mobile bar B30111 is provided with and is connected with transmission belt The two ends of band swing arm B30114, mobile bar B30111 be connected with transfer arm B30112, be connected with transfer arm B30112 for The compressing tablet B30113 of top pressure multi-directional ball B30491.

First grasping mechanism includes chip mechanical gripper B305, is connected to the linking arm B3051 of chip mechanical gripper B305 With the transmission arm B3052 for driving linking arm B3051, transmission arm B3052 is connected to transmission belt simultaneously；Transmission arm B3052 with Anti- excessive lead agency is provided between linking arm B3051, prevents that excessive lead agency includes being connected to the substrate of linking arm B3051 B3053 and one end are connected to substrate B3053 and the other end is connected to the extension spring B3054 of transmission arm B3052；Chip separating side plate B301 is provided with the positive stop B3055 for stopping substrate B3053, implies that when chip mechanical gripper B3052 is by biochip After directing in place, stop continuing directing action by the conflict of substrate B3053 and positive stop B3055, and extension spring B3054 can be after It is continuous to be elongated to allow transmission arm B3052 to continue with conveyor belt motion, because before transmission belt is now still to continue to move to drive The drive link B304 that states, band swing arm B30114 complete the action of their institutional affiliations.

Second grasping mechanism includes the pull bar for being located at the chip pedestal B306 separated on back plate B302, being connected to pedestal B306 B3061, the two pole B3062 and difference that are partial to two chips separating side plate B301 respectively that are articulated with pull bar B3061 head ends It is articulated with two two chips clamping plate B3063 of pole B3062；Chip clamping plate B3063 slidably connects guide rod B3064 jointly, Guide rod B3064 two ends are fixedly connected on chip separating side plate B301, be arranged with guide rod B3064 positioned at chip clamping plate B3063 it Between clamping plate back-moving spring B3065, chip clamping plate B3063 can make move toward one another along guide rod B3064, be connected outside pull bar B3061 There are pulling machinery, such as cylinder device.The side being located in upper base lead-in cavity on chip separating side plate B301 is provided with mutually Independent upper half guiding cell body B307 and lower half guiding cell body B308, upper half guiding cell body B307 is total to lower half guiding cell body B308 With chip guiding conduit is formed, upper half guiding cell body B307 is connected with the upper reset baffle block passed outside chip separating side plate B301 B3071, lower half guiding cell body B308 is connected with the lower reset baffle block B3081 passed outside chip separating side plate B301；Chip is separated Surface on side plate B301 positioned at the outer side of upper base lead-in cavity is provided with the upper positioning gear above upper reset baffle block B3071 The block B3012 and lower position block B3013 below lower reset baffle block B3081, upper position block B3012, upper reset baffle block B3071, lower reset baffle block B3081, lower position block B3013 wear jointly be connected to release link B3014, upper position block B3012, under Position block B3013 is fixedly connected with release link B3014 respectively, upper reset baffle block B3071, lower reset baffle block B3081 respectively with Release link B3014 is slidably connected；Be arranged with release link B3014 positioned at upper reset baffle block B3071 and upper position block B3012 it Between and the back-moving spring B3015 between lower reset baffle block B3081 and lower position block B3013.Upper reset baffle block B3071 And lower reset baffle block B3081 can be slided along release link B3014, so as to realize upper half guiding cell body B307 and lower half guiding cell body The move toward one another of B308, can make chip guide conduit wide up and down while be adaptively relatively distant from when biochip is pried open Degree becomes big.

During real work, transmission belt drive chip mechanical gripper B305 by biochip along chip guiding conduit be sent into In upper chip lead-in cavity；Before biochip will stop in place, transmission belt drives compressing tablet B30113 top pressure multi-directional balls B30491, so that push handle B3049 drives the second rotating shaft B3046 and opened together with second gear B3048 and chip sled block B3047 Beginning stretches into action, until in stretching into the spaced slot in biochip side portion structure；Then transmission belt drives the first transmission group again, First transmission group drives the second transmission group, finally causes that chip sled block B3047 starts to rotate, and pries open action；Then biological core The upper lower unit piece of piece is separated by chip sled block B3047, and lower unit piece can pass through chip guide channel by chip mechanical gripper B305 Road is directed away, and upper unit piece by chip clamping plate B3063 unclamp, fall into lower chips reclaim chamber in.

Be decomposed into after being loaded the complicated applied technical procedure of biochip in incubation reaction, cleaning container by whole system Embathe, comprehensive flushing, unload accommodating base b1, the automatic sub- mistake for prying open lower unit piece on biochip, centrifuge dripping automatically Journey, using lift two-dimentional machinery arm in incubation reaction unit, embathe unit, rinse unit, shift biological between post-processing unit Chip and accommodating base b1, realize the concurrent job or chained job between unit.

Claims (10)

1. a kind of biochip automated cleaning system, including workbench, located at the worktable lifting two-dimentional machinery arm and company It is connected to multiple unit servomotors of the workbench, it is characterised in that：Also include the incubation jointly on the workbench Reaction member, embathe unit, rinse unit and post-processing unit；

The incubation reaction unit includes the first rotating disk（A10）, chip Container for fixing biochip and located at described First rotating disk（A10）Upper the first fixed stop for being used to fix the chip Container（A101）；

The unit that embathes includes the second rotating disk（D10）, located at second rotating disk（D10）It is upper to be used to be put into and embathe biological core The chip rinsing container of piece, the second fixed stop for fixing the chip rinsing container（D101）With located at the workbench The upper headstock gear for being used to open or close chip rinsing container；

The flushing unit includes the 3rd rotating disk（C10）, located at the 3rd rotating disk（C10）It is upper to be used to fixing the of biochip Three fixed stops（C101）, flushing framework for rinsing biochip（C40）With for installing the flushing framework（C40）And With the 3rd rotating disk（C10）The vertical reciprocating mechanism for coordinating（C30）；

The post-processing unit includes the 4th rotating disk（B10）, located at the 4th rotating disk（B10）It is upper to be used to fix the chip appearance Put the 4th fixed block plate of device（B101）, be used on the workbench to separate the chip Container with biochip Base separator and the chip detachment apparatus on the workbench for lower unit piece on biochip to be separate；

The chip Container includes accommodating base（b1）, located at the accommodating base（b1）On edge retaining wall（b2）Be located at The edge retaining wall（b2）On biochip sticking department, the accommodating base（b1）Upper formation is by the edge retaining wall（b2）Enclose Into biochip accommodation space；The biochip sticking department includes being located at the edge retaining wall（b2）On locking seat （b21）, located at the locking seat（b21）On move horizontally space and be placed in the movable block for moving horizontally spatially （b22）；The movable block（b22）It is provided with mobile reduction torsion spring（b23）, the locking seat（b21）It is provided with positioned at the shifting Dynamic reduction torsion spring（b23）The fluting of both sides（b211）, the mobile reduction torsion spring（b23）Be respectively arranged at two ends with and insert two institutes State fluting（b211）In extension；The movable block（b22）Tail end is also associated with shank of the key, and the shank of the key end is provided with lock nut, The space that moves horizontally is through to the locking seat（b21）Outside, the shank of the key stretches out the locking seat（b21）；

First rotating disk（A10）, second rotating disk（D10）, the 3rd rotating disk（C10）, the 4th rotating disk（B10）Point Unit servomotor drives and rotates not as described in one；First rotating disk（A10）, second rotating disk（D10）It is also associated with core Piece shaking device.

2. a kind of biochip automated cleaning system according to claim 1, it is characterised in that：The chip embathes appearance Device includes box body（d1）, located at the box body（d1）The box mouth on top, located at the box body（d1）It is upper to be located at the box mouth side Connection shaft seat（d3）Be connected to the connection shaft seat（d3）Lid（d2）, the lid（d2）It is provided with moving block （d21）, the moving block（d21）It is provided with and the connection shaft seat（d3）The rotating shaft of connection（d211）, the rotating shaft（d211） Rotation reduction torsion spring is provided with, the rotation reduction torsion spring is provided with and insert respectively the moving block（d21）, the connection shaft seat （d3）Two end extensions；The chip rinsing container also includes being located at the box body（d1）It is upper another positioned at the box mouth The cover lock portion of side and located at the box body（d1）On cleaning hole group, the connection shaft seat（d3）With the cover lock Portion is mutually in the box body（d1）On offside；The cleaning includes washing lotion hand-hole with hole group（d13）, washing lotion tap （d14）And tray interior air pressure tap（d15）；The cover lock portion includes being connected to the box body（d1）Locking base Seat（d4）, located at the locking pedestal（d4）On horizontal sliding space and the sliding shoe that is placed on the horizontal sliding space （d5）；The lid（d2）On be additionally provided with lock（d22）, the lock（d22）With the sliding shoe（d5）Coordinate locking；

The cover lock portion also includes being located at the locking pedestal（d4）On be inserted vertically into space, the horizontal sliding space Converged with the space intersection that is inserted vertically into, the sliding shoe（d5）Head end is inserted vertically into space described in being located at, the lock （d22）Described being inserted vertically into space and the lock can be inserted（d22）Be provided with for the sliding shoe（d5）Head end bottom The latch that face is hooked（d221）；

The sliding shoe（d5）It is provided with slip reduction torsion spring（d51）, the locking pedestal（d4）It is provided with and is resetted positioned at slip Torsion spring（d51）The side fluting of both sides（d41）, the slip reduction torsion spring（d51）Be respectively arranged at two ends with and insert two sides Fluting（d41）In extension；The sliding shoe（d5）Front end is provided with for supplying the lock（d22）Push the inclined plane of force （d54）；The sliding shoe（d5）Tail end is also associated with pull handle, and the pull handle end is provided with drawing cap, and the horizontal sliding space is passed through Wear to the locking pedestal（d4）Outside, the pull handle stretches out the locking pedestal（d4）.

3. a kind of biochip automated cleaning system according to claim 2, it is characterised in that：The headstock gear bag Include support body（D20）, the support body（D20）It is provided with left plate（D201）And right plate（D202）, the left plate（D201）On It is provided with for opening cleaning container lid（d2）Cap-opening mechanism, the right plate（D202）It is provided with for closing cleaning container Lid（d2）Closing mechanism；

The cap-opening mechanism includes uncapping using servomotor（D203）, be connected to described uncapping and use servomotor（D203）Uncap Use shaft coupling（D2031）, be connected to described uncapping and use shaft coupling（D2031）Uncap and use screw mandrel（D2032）, be connected to described opening Lid screw mandrel（D2032）Uncap with walking seat（D2033）Described uncapping with walking seat is connected to one end（D2033）And the other end connects It is connected to uncapping with walking frame for lockaid gun（D2034）；The lockaid gun includes unlocking framework（D2035）With located at the unlocking framework （D2035）Interior hollow aisle（D20351）, the unlocking framework（D2035）Close described right plate（D202）Side Side block wall is provided with and the hollow aisle（D20351）The pull handle Ka Dao for communicating（D20352）, the pull handle Ka Dao（D20352） The side block wall is divided into upside retaining wall（D20353）With downside retaining wall（D20354）；The upside retaining wall（D20353）And/or The downside retaining wall（D20354）Inner surface from one end to the other end gradually to the unlocking framework（D2035）The upper and side block The relative opposite side retaining wall of wall is inclined；

The closing mechanism includes closing lid servomotor（D204）, be connected to the closing lid servomotor（D204）Closing lid Use shaft coupling（D2041）, be connected to the closing lid shaft coupling（D2041）Closing lid screw mandrel（D2042）, be connected to the conjunction Lid screw mandrel（D2042）Closing lid with walking seat（D2043）The closing lid is connected to walking seat with one end（D2043）And the other end connects The closing lid of gland device is connected to walking frame（D2044）；

The gland device includes being connected to the closing lid with walking frame（D2044）Mounting bracket（D2045）With located at the mounting bracket （D2045）On pinch roller（D2046）.

4. a kind of biochip automated cleaning system according to claim 1, it is characterised in that：3rd rotating disk （C10）Lower section is connected with Rotational Cylindrical（C201）, the Rotational Cylindrical（C201）Inside is provided with rolling bearing（C202）And with described turn Dynamic bearing（C202）The central shaft of cooperation（C203）；The vertical reciprocating mechanism（C30）Including sequentially passing through the center Axle（C203）And the 3rd rotating disk（C10）Vertical guide rod（C305）With for making the vertical guide rod（C305）Carry out vertically Reciprocating vertical guide-bar driving mechanism；The flushing framework（C40）Including being connected to the vertical guide rod（C305） One framework and the second framework, first framework are provided with first jet（C407）, second framework is provided with second nozzle （C408）.

5. a kind of biochip automated cleaning system according to claim 4, it is characterised in that：The vertical guide rod drives Motivation structure includes vertical guide rod stepper motor（C301）, be connected to the vertical guide rod stepper motor（C301）Vertically lead Bar shaft coupling（C302）, be connected to the vertical guide rod shaft coupling（C302）Vertical guide rod screw mandrel（C303）, connection In the vertical guide rod screw mandrel（C303）Mobile base（C306）Be connected to the Mobile base（C306）Fixed plate （C304）, the vertical guide rod（C305）Lower end is connected to the fixed plate（C304）, the central shaft（C203）Inside be provided with The vertical guide rod（C305）The linear bearing of cooperation；

First framework includes being connected to the vertical guide rod（C305）It is piercing in the 3rd rotating disk（C10）Top bottom Seat（C401）With located at the base（C401）On erecting bed（C402）, the first jet（C407）Located at the erecting bed （C402）On；

Second framework includes being connected to the vertical guide rod（C305）It is piercing in the 3rd rotating disk（C10）Top branch Support axle（C403）, be connected to the support shaft（C403）Top board（C404）, be connected to the top board（C404）Column （C405）Be connected to the column（C405）Between installation band（C406）, the second nozzle（C408）Located at the installation Band（C406）On, the installation band（C406）It is suspended in the 3rd rotating disk（C10）Top.

6. a kind of biochip automated cleaning system according to claim 1, it is characterised in that：The base separates dress Put and separate framework including base（B20）, the base separation framework（B20）Including two pieces of base separating side plates（B201）And connection Two pieces of base separating side plates（B201）Base separate back plate（B202）, the base separating side plate（B201）And the bottom Seat separates back plate（B202）It is collectively forming base and separates longitudinal space, the base separates longitudinal space and guided including upper base Chamber and lower base reclaim chamber；The base separates back plate（B202）On be connected with base guide bar（B204）, the base point From side plate（B201）The base guiding channel for being provided with and being interlinked to the outside in the upper base lead-in cavity（B2011）With the bottom Seat guiding channel（B2011）The base support of cooperation draws section（B2018）And with the base guiding channel（B2011）Cooperating Biochip clamp system and base unlocking mechanism, the guide bar（B204）It is provided with guiding slide（B2045）, the guiding Slide（B2045）On be connected with installing arm（B2041）, the installing arm（B2041）It is provided with base mechanical gripper（B2042）With For the clutch exerted a force to the biochip clamp system.

7. a kind of biochip automated cleaning system according to claim 6, it is characterised in that：The biochip folder Tight mechanism includes being located at the base separating side plate（B201）On axle bed（B2012）, insert the axle bed（B2012）In and by The upper base lead-in cavity passes through the base separating side plate（B201）Movable axis（B2013）, be articulated with the movable axis （B2013）Positioned at the base separating side plate（B201）The active lever of outer one end（B2014）, be connected to the movable bar Bar（B2014）Biochip push rod（B2015）Be fixedly connected on the base separating side plate（B201）And be articulated with described Active lever（B2014）The support shaft at middle part（B2016）；The biochip push rod（B2015）It is logical through base guiding Road（B2011）；The base guiding channel（B2011）It is provided with baffle plate, the biochip push rod（B2015）Through the gear Plate, the biochip push rod（B2015）On be arranged with the reset spring offseted with the baffle plate；

The clutch includes being fixedly connected on the installing arm（B2041）On pushing tow main body（B2043）With located at the top Push away main body（B2043）It is upper to be used for the movable axis（B2013）From the upper base lead-in cavity to the base separating side plate （B201）Extrapolated pushing tow face（B2044）；

The base unlocking mechanism includes being fixedly connected on the base separating side plate（B201）Unblock framework（B2017）With set In the unblock framework（B2017）Interior hollow aisle（B20171）, the unblock framework（B2017）Near the upper base The side wall of lead-in cavity side is provided with and the hollow aisle（B20171）The shank of the key Ka Dao for communicating（B20172）, the shank of the key card Road（B20172）The side wall is divided into upper side wall（B20173）With lower wall（B20174）；The upper side wall（B20173）With/ Or the lower wall（B20174）Inner surface by away from the base separate back plate（B202）One end is near the base point From back plate（B202）One end is gradually to hollow aisle（B20171）Incline；The upper side wall（B20173）It is additionally provided with relative to described Lower wall（B20174）Close described base separate back plate（B202）The extension of side；

The base support draws section（B2018）Including located at the base separating side plate（B201）Inner surface respectively be located at the bottom Seat guiding channel（B2011）The epimere of upper and lower both sides（B20181）And hypomere（B20182）；The epimere（B20181）It is provided with phase For the hypomere（B20182）Close described base separate back plate（B202）The lengthening section of side, the lengthening section is provided with Base is squeezed and cut somebody's hair（B20183）；

The installing arm（B2041）Haulage gear is externally connected with, the haulage gear includes power for traction machine（B205）, be connected to The power for traction machine（B205）Traction shaft coupling, be connected to the traction screw mandrel of the traction shaft coupling（B2051）、 It is connected to the traction screw mandrel（B2051）Connecting seat（B2052）The connecting seat is connected to one（B2052）And it is another Head is connected to the installing arm（B2041）Transmission bridge（B2053）.

8. a kind of biochip automated cleaning system according to claim 1, it is characterised in that：The chip separates dress Put including transmission motor, be connected to the transmission motor driving gear, for the driving gear synchronous axial system The transmission belt of driven gear and the connection driving gear and the driven gear；The chip detachment apparatus are also including chip point From frame（B30）, the first grasping mechanism for biochip to be sent into the chip separator frame and coordinate first gripper Structure is used to clamp the second grasping mechanism of unit piece on biochip and the fractionation for lower unit piece on biochip to be separate Mechanism, the detachment means and first grasping mechanism are commonly connected to the transmission belt；The chip separator frame（B30）Bag Include two chips separating side plate（B301）With two pieces of chip separating side plates of connection（B301）Chip separate back plate（B302）, The chip separates back plate（B302）With the chip separating side plate（B301）Together form chip and separate longitudinal space, it is described Chip separates longitudinal space to be included for first grasping mechanism, second grasping mechanism and the detachment means cooperating Upper chip lead-in cavity and for house unit piece on biochip lower chips reclaim chamber.

9. a kind of biochip automated cleaning system according to claim 8, it is characterised in that：The detachment means bag Include the drive link for being connected to the transmission belt（B304）, be connected to the drive link（B304）Connecting rod（B3041）, by described Drive link（B304）The first transmission group for driving and the second transmission group driven by first transmission group；The connecting rod （B3041）It is provided with driving cog（B30411）；

First transmission group includes being respectively arranged on two chip separating side plates（B301）On the first axle bed（B3042）、 Insert two first axle beds（B3042）And through the first rotating shaft of the upper chip lead-in cavity（B3043）Be connected to The first rotating shaft（B3043）The first gear at two ends（B3044）, one of them described first gear（B3044）With the biography Dynamic tooth（B30411）Engagement connection；

Second transmission group includes being respectively arranged on two chip separating side plates（B301）On the second axle bed（B3045）、 It is respectively implanted two second axle beds（B3045）And stretch into the second rotating shaft of the upper chip lead-in cavity（B3046）, connection In second rotating shaft（B3046）The chip sled block of the one end in the upper chip lead-in cavity（B3047）Be connected to Second rotating shaft（B3046）The second gear of the other end（B3048）, the second gear（B3048）With the first gear （B3044）Engagement connection；Second rotating shaft（B3046）On be additionally provided with positioned at second axle bed（B3045）With described second Gear（B3048）Between rotating shaft back-moving spring（B30461）；

First grasping mechanism includes chip mechanical gripper（B305）, be connected to the chip mechanical gripper（B305）Connection Arm（B3051）With for driving the linking arm（B3051）Transmission arm（B3052）, the transmission arm（B3052）Connect simultaneously In the transmission belt；

Second grasping mechanism includes separating back plate located at the chip（B302）On pedestal（B306）, be connected to the base Seat（B306）Pull bar（B3061）, be articulated with the pull bar（B3061）Two pieces of the deflection respectively chip separating side plate of head end （B301）Two poles（B3062）Be hingedly connected to two poles（B3062）Two chips clamping plate（B3063）； The chip clamping plate（B3063）Guide rod is slidably connected jointly（B3064）, the guide rod（B3064）Two ends are fixedly connected on institute State chip separating side plate（B301）, the guide rod（B3064）On be arranged with positioned at the chip clamping plate（B3063）Between clamping plate Back-moving spring（B3065）.

10. a kind of biochip automated cleaning system according to claim 1, it is characterised in that：The chip rocks Device includes chassis（e1）And telophragma（e2）, the chassis（e1）It is connected to the unit servomotor and is watched by the unit Take motor drive, the telophragma（e2）Positioned at the chassis（e1）With first rotating disk（A10）/ second rotating disk （D10）Between, the chassis（e1）With the telophragma（e2）Between be provided with multiple the first connectors for supporting（e3）, institute State telophragma（e2）With first rotating disk（A10）/ second rotating disk（D10）Between be provided with and multiple for supporting and make described First rotating disk（A10）/ second rotating disk（D10）Second connector of eccentric rotary（e4）, one of them described second connection Part（e4）It is connected with lead agency；

First connector（e3）Including being connected to the telophragma（e2）Upper pedestal（e31）, be connected to the chassis （e1）Lower base（e32）Be connected to the upper pedestal（e31）With the lower base（e32）Between breeze way（e33）；

Second connector（e4）Including being fixedly connected on first rotating disk（A10）/ the second rotating disk（D10）Upper axle bed （e41）, be fixedly connected on the telophragma（e2）Lower axle bed（e42）With simultaneously be rotationally connected with the upper axle bed（e41）And The lower axle bed（e42）Rotor；The rotor includes main body block（e43）, located at the main body block（e43）Upper surface and With the upper axle bed（e41）Rotate the upper connecting shaft of connection（e431）With located at the main body block（e43）Lower surface and with it is described Lower axle bed（e42）Rotate the lower connecting shaft of connection（e432）, the upper connecting shaft（e431）Axial line and the lower connecting shaft （e432）Axial line not on the same line；

The lead agency includes being located at the chassis（e1）On drive motor（e5）With the drive motor（e5）Transmission connects The belt pulley for connecing（e51）And with the belt pulley（e51）The wheel shaft of connection（e52）, the wheel shaft（e52）It is connected with described second Part（e4）Lower connecting shaft（e432）It is fixedly connected or is integrally formed.