CN206020428U - A kind of collection and detection device - Google Patents
A kind of collection and detection device Download PDFInfo
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- CN206020428U CN206020428U CN201620948262.5U CN201620948262U CN206020428U CN 206020428 U CN206020428 U CN 206020428U CN 201620948262 U CN201620948262 U CN 201620948262U CN 206020428 U CN206020428 U CN 206020428U
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Abstract
This utility model is related to a kind of collection and detection device, for collecting and detecting fluid sample, including housing the detection plate of testing element and collecting the urine cup of storage fluid sample, detection plate is fully inserted in urine cup, and between urine cup liquid communication, urine cup includes opening, diapire and side wall, includes contact surface on urine cup sidewall；The collection and detection device has collects position and test position, and collection and detection device is in when collecting position, by urine cup bottom wall supports collection and detection device；When collection and detection device is in test position, the testing element in collection and detection device, and detection plate is supported perpendicular to contact surface by the contact surface of urine cup sidewall.This utility model collection and detection device simple structure, using blowing manufacturing process, low cost of manufacture；Test is opened as needed can, the convenient determination detection time started；Using transversely arranged test strips, detection intracavity of the same area, more strips of can arranging, more projects can be tested simultaneously.
Description
Technical field
This utility model belongs to medical diagnosis class article technical field, and more particularly to one kind can quickly be collected and be detected
Whether the collection and detection device of one or more target analytes is contained in sample.
Background technology
Following background technology is used to help reader and understands this utility model, and is not construed as prior art.
The abuse problem of medicine or drugs has become increasingly serious social problem.U.S. Department of Health and Human Services's door
The investigation of 2003 finds that the ratio of Drug abuse is up to 8.2% in the American of more than 12 years old.With sending out for economic society
Exhibition, the ratio of drug dependence are gradually increased, and the medicament categories that abuses are also more and more.
Liquid sample is collected using detection means typically to the quick detection of the Drug Abuses such as drugs, then by correlation
Technical staff's insertion detection strip simultaneously makes a part of submergence of detection strip in the sample, takes out strip and read after certain time
Testing result.However, in order to fight with drugs and monitor drug problem, this test has become a mark when many
Quasi-ordering, for example employ, go to school, physical culture, law enforcement etc., operated by amateur testing staff.It is therefore desirable to provide a kind of detection
Device, it is to avoid operator touch the sample in open liquid collection and detection device, jeopardize the health of operator.With
When, it is also desirable to the collection and detection device can stored samples, with facilitate sample in the case where occurring objection to testing result multiple
Inspection.The test for being additionally, since drug dependence has become a standardization program, it is also desirable to which the price of detection means is sufficiently minimized, energy
Enough meet the demand of large-scale use.
Further, since smoker has the motivation for concealing drug abuse or Drug Abuse, there is sample adulteration；
Meanwhile, cannot accurately estimate the substantially species of the medicine used by person to be detected before detection, accordingly, it would be desirable to utilize an inspection
Surveying device, sample adulteration situation and the possibility of multiple types is sucked as far as possible medicine is simultaneously detected in one-time detection.
In some detection means existing, there is the lid that the test strips of multiple detection different pharmaceuticals are placed on detection means
On, after closeing the lid after fluid sample is collected, inverted device is realizing detecting.But the limited space of lid, the examination that can be accommodated
Paper slip quantity is also few, and therefore, the medicine that can be detected simultaneously in same sample is relatively fewer.Also, this detection means is needed
Will be in the simultaneously sealer sealing of integration testing element in lid, complex in manufacturing process, high cost.Meanwhile, these devices
Operationally also complex, the initial time of the inconvenient accurately interpretation detection of lay operators.
Utility model content
This utility model provides a kind of collection and detection device of new fluid sample, overcomes existing detection means
Problem, the device collect sample after only need overturn (toppling over) i.e. can achieve detection, both easy to operate and can quickly interpretation examine
The initial time of survey, meanwhile, the device of the structure can accommodate more testing elements, realize detection more simultaneously after primary sample
Many medicines, also, the device is simple and convenient in manufacturing process, greatlys save manufacturing cost.
First, a kind of collection and detection device for providing in this utility model, for collecting and detecting fluid sample, including receiving
The detection plate for holding testing element and the urine cup for collecting storage fluid sample, detection plate is fully inserted in urine cup, and with urine cup it
Between liquid communication, it is characterised in that urine cup includes opening, diapire and side wall, includes contact surface on urine cup sidewall；The collection
Detection means has collects position and test position, and collection and detection device is collected by urine cup bottom wall supports in when collecting position
Detection means；When collection and detection device is in test position, collection and detection device is supported by the contact surface of urine cup sidewall, and is detected
Testing element in plate is perpendicular to contact surface.
In this utility model, contact surface refer to for other faces or point contact to support device of the present utility model
One face, the contact surface can also include that at least three contact to support the device of utility model to connect with other faces or point
The face that contact is located, the face at contact point place or contact surface can support whole collection when needing as bottom surface
Detection means, and contact with that supporting surface for supporting detection means.
Some preferred embodiment in, collection and detection device collect sample after, by collect position be turned to up to detecting position
Put, carry out the detection of sample.Wherein, it can topple over or overturn 45 °～135 ° to overturn or topple over, 60 °～120 °, 75 °～
105 °, 80 °～100 °, or 85 °, 90 °, 95 °.Further, it is also possible to any suitable angle, the angle only needs full
When position is collected, liquid sample will not overflow or flow to test chamber foot；In the state of detection, fluid specimen collection detection means
Can keep stable under the support of contact point, fluid sample can flow into test chamber from collecting chamber.
In some embodiments, the detection plate is connected to the side in contact point face.
In the embodiment being more highly preferred to, detect that the testing element of intracavity also runs through diapire and receipts both perpendicular to collecting chamber
The axis of Ji Kou.That is, when testing element is detected after the collection and detection device is toppled over, testing element is perpendicular in liquid
The state of plane, so as to ensure that liquid sample reaches the other end by one end of testing element, realizes horizontal mobility to complete to detect.
That is, in a preferred embodiment, when collection and detection device is in collection position, detecting that the testing element level of intracavity is put down
Row is arranged in detection intracavity.Likewise, testing element is for collecting chamber, it is horizontally arranged on the wall of collecting chamber side, so as to
More testing elements can be arranged, makes the realization of detection means disposably detect multiple different drug detection.
Some preferred embodiment in, one end of the nearly urine cup opening of detection plate has allows liquid to be flowed into detection from urine cup
The injection port of plate and gas is allowed to be flowed into the gas channel of urine cup from detection plate.
In some embodiments being more highly preferred to, air inlet that gas channel includes being connected with detection plate internal cavity,
The steam vent being connected with urine cup internal cavity, and connect the excessive liter passage of the air-flow of air inlet and steam vent.
In some embodiments, the position of the sample application zone of testing element, injection port and air inlet is neighbouring to be contacted
Face.So, after device is overturn to test position, bottom surface of the contact surface as device, sample application zone, injection port and air inlet
Kong Yin is at the bottom of device adjacent to contact surface.
That is, the injection port and gas channel (air inlet mainly on passage) in detection plate is close to urinate
The position of cup opening, in such manner, it is possible to make collection and detection device when position is collected, injection port and gas channel (air inlet) are located at
At collection and detection device higher position, the sample in urine cup will not touch injection port, so as to liquid between urine cup and detection plate
It is not attached to lead to.And in the case of the neighbouring contact surface in the position of the sample application zone of testing element, injection port and air inlet,
When collection and detection device is in test position, injection port and gas channel be then located at collection and detection device compared with bottom position at, so as to
Urine cup inner sample liquid can be made to be exchanged to detection plate by injection port, there is liquid sample engaged test first the very first time
The sample application zone of element, tested element is obtained realizes detection；Also, the gas in detection plate can pass through gas channel
It is discharged in urine cup.
In some embodiments, when collection and detection device is located at inspection positions, unit is not higher than tested in injection port position
The position of the sample application zone of part；Air inlet hole site is higher than injection port position, and air inlet hole site is less than testing element labelling
The position in region.The height of air inlet may decide that liquid sample enter the amount of liquid of detection plate number, that is, can
To control the height of fluid level in detection plate.In the detection, it is undesirable that liquid sample is touched on testing element except sample connects
By the region outside region, therefore, the highly desirable position positioned at marked region of the air inlet.
In other embodiments, the collection and detection device also includes the lid for covering and sealing urine cup.Lid is covered
And after sealing urine cup, the state of the urine cup and detection plate of collection and detection device in a sealing is made, so as to for urine cup and inspection
Fluid exchange between drafting board provides condition.
Some preferred embodiment in, when detection means is in test position, the position of steam vent is higher than air inlet
Position.The position of steam vent can be such that gas in detection plate is smoothly expelled in urine cup higher than the position of air inlet.
In some specific embodiments, draw-in groove in the detection plate, is provided with, described gas channel is in draw-in groove.
Air inlet and steam vent are respectively positioned on draw-in groove.
Now, detection plate is not directly connected with urine cup, and detection plate is connected with urine cup by draw-in groove, detection plate endogenous cause of ill liquid
Enter and expellant gas are overflow by the air-flow that the air inlet on draw-in groove is entered in draw-in groove and rise passage, reach the aerofluxuss on draw-in groove
Hole, is discharged gas outside test chamber by steam vent, reaches and collect intracavity.
In some specific embodiments, the size of air inlet between 0.5-1mm, liquid reach air inlet position after, by
In surface tension of liquid phenomenon air inlet by liquid seal so that the gas and liquid in detection plate reaches balance so that
Liquid is maintained at the height of air inlet, and the testing element so as to ensure that in detection plate can be absorbed and be sufficiently used for detection
Sample, will not affect testing result again because amount of liquid is excessive.
Some preferred embodiment in, urinate cup sidewall and there is at least one section side wall in cambered surface indent, collect detection dress
Put in test position when, the side wall in cambered surface indent be contact surface.
In the sidewall sections of the sidewall design cambered surface indent of urine cup, on the one hand, the holding arc of the cambered surface indent and operator
Degree connects, and is conducive to operator to hold collection and detection device；On the other hand, the design of the larger depression of interior recess, can reduce urine
The volume of cup, under conditions of same volume samples collecting amount, with higher liquid level, when upset urine cup starts to test, energy
Enough samples for ensureing to have abundant volume enter test chamber, reduce because experimenter mismatches the situation of caused detection failure.
In some embodiments being more highly preferred to, urinate cup sidewall have at least one section in plane side wall and at least one section be in
The side wall of cambered surface indent；When collection and detection device is in test position, the side wall of cambered surface indent is supported as contact surface collects inspection
Device is surveyed, flat sidewall is perpendicular to horizontal plane.
In some embodiments, detection plate is located at flat sidewall.But detection plate is not limited at flat sidewall, as long as energy
Enough satisfactions install testing element.Herein, detection plate is arranged on the side-walls in plane, is conducive to disposing as much as possible
Test strip, is also convenient for liquid sample in detection plate flows, facilitate each test strip can under conditions of roughly the same with sample
This haptoreaction, is conducive to testing conditions control.On the other hand, test chamber is set in the side-walls in plane, compared to curved surface,
Testing result can be observed more easily, be conducive to accurate interpretation testing result.
In some highly preferred embodiments, urine cup sidewall is with the side wall that a section is in plane, one section in cambered surface indent
Side wall and one section of side wall in cambered surface evagination, three sections of side walls are sequentially connected and connect, enclose to form whole urine cup sidewall；Detection plate position
At the inner chamber body of flat sidewall, the side wall in cambered surface indent is contact surface.The cambered surface of sunken inside and outer protrusion is taken with hand and is held
The shape of state fits, and conveniently takes.
Be connected with detection plate planar outer walls be connected to cambered surface indent side wall side, after detection means overturns, arc
The side wall of face indent becomes the bottom of detection means, supports detection means, and is located at the flat of the side of the side wall of cambered surface indent
Surface side wall is still in side wall-like state, and the outer wall of the cambered surface indent perpendicular to bottom, so that the liquid for collecting intracavity is led to
Cross injection port and enter the test chamber being connected at flat sidewall, realize detection.
Some preferred embodiment in, urine cup sidewall on include at least one be recessed；Depression is located at what contact surface was located
In face or contact surface to face in.
When operator holds this utility model device, check testing element for convenience, generally hold with detection plate this
Other sidewall sections of one flat sidewall, wherein, including the contact surface being connected with flat sidewall, and another place's phase of flat sidewall
Side wall even, this another place side wall are located at the opposite of contact surface, that is to say, that contact surface is connected to opposite respectively with contact surface
It is connected on the both sides of flat sidewall.And, in order to stably hold device, the depression for accommodating that finger is placed can be set at hand griping position.
Namely of the present utility model at least one is recessed, and the depression is may be located on contact surface, it is also possible to positioned at the opposition of contact surface
On face, depression also can be equipped with respectively on contact surface and opposite.
Some preferred embodiment in, detection plate be inserted into urine cup in plane side wall and the depression between.
Beneficial effect
Collection and detection device simple structure of the present utility model, can adopt blowing manufacturing process, low cost of manufacture；Can
Open test as needed, the convenient determination detection time started, determine the optimal result viewing time；Vertical compared to traditional
The test strips of arrangement, the application adopt transversely arranged test strips, detection intracavity of the same area, more examinations of can arranging
Bar, can test more projects simultaneously.
Description of the drawings
For a kind of collection and detection device schematic diagram of the present utility model, (collection and detection device is located at when collecting position Fig. 1
Schematic diagram)；
Fig. 2 is that (collection and detection device is located at and detects test chamber generalized section in collection and detection device of the present utility model
Schematic diagram during position)；
Fig. 3 is the decomposing schematic representation of collection and detection device of the present utility model；
Fig. 4 is the front schematic view of detection plate lower plate of the present utility model；
Fig. 5 is the back side (reverse side) schematic diagram of detection plate lower plate of the present utility model.
Reference：
Collection and detection device 800, collecting chamber, urine cup 100, test chamber, detection plate 200, testing element, test strips 300 are received
Collection bottom of chamber wall 110, collecting chamber side wall 120, the collection port 130 of collecting chamber, face (cambered surface concave side wall, contact that contact point is located
Face) 121, the face (flat sidewall) 122 that test chamber is located, the side wall 123 of cambered surface evagination, test chamber one end 204, test chamber is another
End 203, injection port 210, gas channel air inlet 220, draw-in groove (gas channel) 230, steam vent 240, testing element groove
260, detection plate upper plate 201, detection plate lower plate 202, detection plate lower plate front 2021, back 2022 under detection plate, after draw-in groove
Plate 231, depression 124, the sample application zone 301 of testing element, the marked region 302 of testing element, lid 400
Specific embodiment
The structure that below this utility model is related to or these technical terms for being used are described further.
Detection
" detection " represents chemical examination or tests a kind of material or material whether there is, such as, but be not limited to this, chemicals
Matter, organic compound, inorganic compound, metabolism product, medicine or drug metabolite, organic organization or organic organization
Metabolite, nucleic acid, protein or polymer.In addition, detection represents the quantity of test substances or material.Furtherly, chemical examination is gone back
Represent immune detection, chemical detection, enzyme detection etc..
Antibody
" antibody " refers to immunoglobulin, either natural or some or all of synthesis.This term is also wrapped
Include the derivant for wherein keeping the antibody of binding ability, also include any containing binding domain homologue with immunoglobulin or
The largely protein of homologous binding domain.These protein are derived from natural materials, it is also possible to part or
All synthesize.A kind of antibody is probably monoclonal or polyclone.A kind of antibody is probably any immunoglobulin
A member in type, including the immunoglobulin class of any mankind：IgG, IgM, IgA, IgD, IgG and IgE." antibody fragment "
It is derivant or a part less than total length of antibody of antibody.Antibody fragment can retain at least one full length antibody
The notable site of binding ability.The example of antibody fragment includes Fab, Fab', F (ab')2, scFv, Fv, dsFv dimer, and Fd
Fragment, but not only include the above.
Test strips
Apply to the horizontal effluent reagent strip that test strips of the present utility model can be known as, the tool of these reagent strips
Body structure and Cleaning Principle are technology known to persons skilled in the art in the prior art.Common reagent strip, including
Sample application zone, marked region, detection zone and suction zone, including detecting whether containing analyte in detection zone
, after detection terminates, can there is detection line 241 and the control line for representing result in detection zone in the necessary chemical substance of matter
242.General conventional detectable bar includes nitrocellulose filter (NC for nitrocellulose assay strip, i.e. detection zone
Film), specific binding molecule is fixed on nitrocellulose filter to show the end of detection, can also be cellulose acetate membrane or Buddhist nun
Imperial film etc..The width of usual test strips is between 3mm-6mm.
The type of analyte
The example that can be used in the analyte of this utility model stable detection includes (but not only including) human chorionic
Film promoting sexual gland hormone (hCG), lutropin (LH), ovarioestrogen (FSH), hepatitis C virus (HCV), hepatitis B virus (HBV),
The medicine of hepatitis B surface antigen, HIV (human immunodeficiency virus) and any abuse.Analyte can be in any liquid or liquefied sample
Detect, for example urine, saliva, blood, blood plasma or serum.The example of other analytes also has flesh ammonia acid anhydride sour, bilirubin,
Nitrite, protein (nonspecific), blood, leukocyte, blood glucose, heavy metal and toxin, bacterial component are (for example, specific
The special protein of the antibacterial of type and sugar, such as colon bacillus 0157:H7, staphylococcus aureuses, Salmonella are produced
Gas capsular clostridium, Campylobacter, listeria monocytogenes, V. parahaemolyticus, or wax bacillus cereuss).Any other is suitable
The analyte for closing lateral flow test format can be detected with this device.
The type of sample
Any kind of sample can be tested with device of the present utility model, including body fluid (for example, urine and its
Its body fluid, and clinical sample).Fluid sample may originate from solid or semisolid sample, including excrement, biological tissue and
Foodstuff samples.These solids and semisolid sample fluid sample can be transformed into by any suitable method, for example exist
Mix in a kind of appropriate liquid, stamp broken, soaking, incubation, dissolving or enzymolysis solid sample (for example, water, phosphate buffer
Or other buffer)." biological sample " includes the sample from animal living, plant and food, also include urine, saliva,
Blood and blood constituent, cerebrospinal fluid, vaginal swab, seminal fluid, feces, perspiration, secretions, tissue, organ, tumor, tissue and device
The conditioned media of the culture of official, cell culture and there, either people or animal.Foodstuff samples include processed
Composition of food and last product, meat, cheese, wine, milk and drinking water.Plant sample is included from any plant, plant
The sample of the conditioned media of tissue, plant cell cultures and there." environmental sample " is the sample (example that those are derived from environment
Such as, the sample of lake water sample or other water bodys, sewage sample, pedotheque, groundwater sample, seawater sample, runoff water
Sample).The waste of sewage and correlation can also be included in environmental sample.
In the following detailed description, the subsidiary reference word of legend is a part here, and it is illustrating this
Utility model can actable specific concrete scheme mode illustrating.We are not precluded from this utility model and can also carry out which
Its concrete scheme and changing structure of the present utility model without prejudice to use range of the present utility model in the case of.
As depicted in figs. 1 and 2, it is that collection and detection device 800 of the invention mainly includes collecting chamber 100 and test chamber
200, and the lid 400 of sealing collecting chamber.Collecting chamber 100 is used for collecting and storing fluid sample, and test chamber 200 is sealed for one
The cavity for closing, for housing testing element 300, being capable of liquid communication between the test chamber 200 and collecting chamber 100.Work as liquid
After being collected in collecting chamber 100, lid 400 is covered and seals the collection port 130 of collecting chamber, makes the liquid in collecting chamber 100
Polluted without being leaked to outside collection and detection device 800 by sealing, while making collecting chamber 100 and the test chamber 200 of connection
The space of a sealing is formed, facilitates follow-up detection to operate.
On the collection and detection device 800, with collection position (Fig. 1) and test position (Fig. 2).Collection and detection device
800 in when collecting position, and the diapire 110 of collecting chamber is contacted with supporting surface (placing the plane of collection and detection device 800), that is, receive
The diapire 110 in collection chamber is used for supporting the collection and detection device 800；When collection and detection device 800 is located at the collection position, inspection is collected
Survey device 800 to collect and stored samples.When collection and detection device 800 is located at test position, collection and detection device 800 passes through
On collecting chamber side wall 120, supporting, specifically, there is on collecting chamber side wall 120 one includes at least three at least three contact points
The face 121 that individual contact point is formed, the face 121 are used for supporting the collection and detection device 800 during test position；Collection and detection device
800 be located at test position when, collection and detection device 800 start detect sample.In one specific embodiment, as shown in figure 1, receiving
Collection detection means 800 is located at collects position, is used as the bottom of collection and detection device 800 and is put by the diapire 110 of collecting chamber
The supporting surface contact of collection and detection device 800 is put, whole collection and detection device 800 is supported；And in Fig. 2, collection and detection device
800 are in test position, and a part for collecting chamber side wall 120 supports whole collection as the bottom of collection and detection device 800
Detection means 800, now, the face 121 that at least three contact points are located is located on collecting chamber side wall 120, and is detected as collecting
The bottom of device 800 supports whole collection and detection device 800.
Collection and detection device 800 can reach test position by upset by position is collected, and that is to say collection detection dress
The bottom that supports for putting 800 is changed into a face 121 of collecting chamber side wall from collecting chamber diapire 110, specifically, can pass through to receive
Collection detection means 800 overturns certain angle to realize.In the present embodiment, according to collecting chamber and the structure of test chamber, Ke Yitong
Cross to turn over collection and detection device 800 and turn 90 degrees, the support bottom surface of collection and detection device 800 is transformed to by collecting chamber diapire 110
A part for the side wall 120 of collecting chamber, reverses direction can be located at according to this face 121 of the collecting chamber side wall for supporting and receive
The which side in collection chamber 100 needs to overturn the supporting surface with three contact points to the bottom of collection and detection device 800 adjusting
Portion.
In use, collection and detection device 800 is first located at and collects position, collect liquid sample, collect detection dress
After the completion of putting 800 collection samples, collection and detection device 800 is turned to up to test position by position is collected, the inspection of sample is carried out
Survey.In collection and detection device of the present invention 800, collection and detection device 800 is turned over and is turn 90 degrees.In the upset of collection and detection device 800
During, the liquid in collecting chamber 100 flows because of the conversion of 800 position of collection and detection device, and by collecting chamber 100 and inspection
That surveys the connection of chamber 200 is partially into test chamber 200, and engaged test element 300, and testing element 300 is detected to sample.
In some preferred embodiments, test chamber 200 is connected to the side wall 120 of collecting chamber, more specifically, test chamber 200
It is connected to the side in contact point place face 121.So, when collection and detection device 800 is located at test position, i.e. collecting chamber side wall
At least three contact point place faces 121 as 800 bottom of collection and detection device when, test chamber 200 and be located at test chamber 200 in
Testing element 300 perpendicular to bottom (namely perpendicular at least three contact point place faces 121), meanwhile, in test chamber 200
Testing element 300 is also perpendicularly to the fluid level of the liquid sample in collecting chamber 100, so as to ensure that sample can smoothly enter inspection
Chamber 200 is surveyed, is contacted with the testing element 300 of intracavity and is completed to detect.More excellent, testing element 300 is also both perpendicular to collection
Chamber 100 is through diapire 110 and the axis of collection port 130.More specifically, when collection and detection device 800 is located at and collects position, survey
Examination element 300 is horizontally arranged in test chamber 200, and is horizontally arranged on 100 side wall of collecting chamber (shown in Fig. 3)；Work as collection
When detection means 800 is turned to test position, testing element 300 is vertical row relative to 800 bottom 121 of collection and detection device
Row, as shown in Figure 2.
More specifically in embodiment, in order to ensure that sample sequentially flows through testing element 300, detection, testing element is realized
The face 121 that is located adjacent at least three contact points of sample application zone 301.Namely collection and detection device 800 is in detecting position
When putting, the sample application zone 301 of testing element is located at the bottom of testing element 300, to ensure sample application zone 301 at first
Touch liquid sample.
In the collection and detection device 800 of the present invention, test chamber 200 is located on collecting chamber side wall 120, test chamber one end 203
The diapire 110 of neighbouring collecting chamber, collection port 130 of the test chamber other end 204 adjacent to collecting chamber.Wherein, test chamber is neighbouring collects
One end 204 of mouth includes allowing liquid to be flowed into the injection port 210 of test chamber 200 from collecting chamber 100 and allow gas from test chamber stream
Enter to collecting chamber gas channel 230.Injection port 210 makes liquid communication between collecting chamber 100 and test chamber 200, is collecting inspection
During survey device 800 is overturn to test position by collection position, the liquid sample in collecting chamber 100 passes through injection port 210
Enter in test chamber 200.And gas channel 230 is then used for what discharge was extruded because of the entrance of liquid sample in test chamber 200
Gas.Therefore, when collection and detection device 800 is located at test position, in order to ensure that sample smoothly enters test chamber 200, air-flow
The position of passage 230 needs the position higher than injection port 210.
In some embodiments, gas channel 230 is overflow to rise passage and be connected to the excessive passage that rises of the air-flow by an air-flow and (is schemed
In fail to illustrate) air inlet 220 at two ends and air vent 240 constitute.In order to ensure that the gas channel 230 can be realized discharging inspection
The gas in chamber 200 is surveyed, when collection and detection device 800 is located at test position, the position of steam vent 240 is higher than air inlet 220
Position.In one specific embodiment, air inlet 220 is located at the bottom of gas channel 230, and steam vent 240 is located at gas channel
230 top.
In practical operation, the sample for entering test chamber 200 needs the sample application zone of engaged test element 300 first
301, and only contact with sample application zone 301, just can guarantee that the realization of the detection of collection and detection device 800.In the present invention,
The height that sample enters test chamber 200 is adjusted by the position of injection port 210 and the position of gas channel 230, makes liquid
The level control of body sample is in the sample application zone 301 of testing element.Specifically, when collection and detection device 800 is located at inspection
When location puts place, 210 position of injection port is not higher than the position of the sample application zone 301 of testing element；The air inlet of gas channel
220 position of hole is higher than 210 position of injection port, and 220 position of air inlet of gas channel is less than testing element marked region 302
Position.Liquid sample in collection and detection device 800 by collecting during position is turned to up to test position, collecting chamber 100
Put and change, the liquid sample in collecting chamber 100 occurs change in location therewith, liquid flows to the contact in 130 direction of collection port
The face 121 that point is located, so as to flow into injection port 210 simultaneously adjacent to collection port 130 and contact point place face 121, by sample introduction
Mouth 210 enters test chamber 200, reaches at the sample application zone 301 of the testing element 300 being located in test chamber 200 (because of sample introduction
210 positions of mouth are not higher than 301 position of sample application zone), meanwhile, the gas of test chamber 200 is extruded, edge because liquid is entered
The gas channel 230 being in communication with the outside is discharged outside test chamber 200.Specifically, pass through air inlet after the gas of test chamber 200 is extruded
Hole 220 enters the excessive liter passage of air-flow, overflows to rise in passage in air-flow and flow to up to steam vent 240, then is discharged by steam vent 240 whole
Individual gas channel 230, namely be discharged to outside test chamber 200.When collection and detection device 800 is totally turned over to test position,
Liquid sample goes successively to test chamber 200, until liquid level of the liquid sample in test chamber 200 reaches entering for gas channel
When at 220 position of pore, the liquid seal air inlet 220 makes not connect between gas channel 230 and test chamber 200, test chamber
200 are sealed, and the gas and liquid in test chamber 200 reaches poised state, and the liquid in collecting chamber 100 does not enter back into test chamber
200, so as to the liquid level in test chamber 200 is identical with the position height of air inlet 220, positioned at the marked region of testing element
302 lower section, i.e. the sample application zone 301 of only testing element 300 being capable of contact liq sample.
The collecting chamber side wall 120 of the collection and detection device 800 of the present invention includes at least one section side wall in cambered surface indent
121, at least three contact points for supporting are located at the side wall 121 in cambered surface indent, therefore, collection and detection device 800
When being in test position, the side wall 121 of the cambered surface indent supports collection and detection device 800.Or, collecting chamber side wall 120 is also
Including at least one section side wall 122 in plane, the side wall 122 of the plane is used for accommodating or connecting detection chamber 200.And, more
In preferred embodiment, collecting chamber side wall 120 include at least one section side wall 121 in cambered surface indent and at least one section be in plane
Side wall 122, described flat sidewall 122 are connected with the side wall 121 of cambered surface indent.Wherein, test chamber 200 is located at the side wall of plane
At 122, at least three contact points are located on the side wall 121 in cambered surface indent；When collection and detection device 800 is in test position
When, the side wall 121 of cambered surface indent supports collection and detection device 800 as bottom.
In a specific embodiment in the present invention, detection means 800 by one end open urine cup 100 as collection
Chamber, and test chamber is made up of detection plate 200, the insertion of detection plate 200 urine cup 100 is interior and is fixed on the medial wall of urine cup 100.Such as
Shown in Fig. 3,200 points of detection plate is detection upper plate 201 and detection lower plate 202, and there is in detection lower plate 202 multiple receiving to test unit
The groove 260 of part 300, testing element 300 are placed in groove 260, and then detection upper plate 201 is covered and sealing detection lower plate
202 cavitys 200 for forming sealing, after the insertion urine cup 100 of detection plate 200, testing element 300 is laterally positioned in urine cup sidewall 120
On, namely testing element 300 is perpendicular to the axial direction of urine cup 100, also, testing element 300 is used for support perpendicular to urine cup 100
Contact surface 121.
In some embodiments, testing element 300 is the reagent paper for realizing analyte detection in sample using horizontal mobility
Bar.The test strips include sample application zone 301, marked region 302, detection zone and suction zones successively by bottom to top
Domain.
Make that urine cup 100 is connected with detection plate 200 is to be close to the sample introduction at urine cup opening 130 positioned at detection lower plate 102
Mouthfuls 210, as shown in Fig. 2 the injection port 210 is also located at the bottom of detection plate 200 simultaneously, be close to urine cup for support contact surface
121, its position is not higher than the sample application zone 301 of test strips.Also there is draw-in groove 230, the draw-in groove in the top of injection port 210
230 are used for discharging the gas in detection plate 200.
In one specific embodiment, as shown in figure 4, the draw-in groove 230 is by being arranged on detection plate lower plate front 2021
Bossing is formed with 231 fixing seal of draw-in groove back plate.Draw-in groove 230 is located at detection plate lower plate with test strips 300 in same direction
202 adjacent to one end of urine cup opening 130 (collection port of collecting chamber).230 bottom of draw-in groove (one end of neighbouring injection port 210) has
Air inlet 220, air inlet 220 make the hollow space (air-flow overflows and rises passage, not shown in figure) of draw-in groove be connected with detection plate 200
Logical, in a specific embodiment, air inlet is located at the front of draw-in groove, namely the front 2021 of detection plate, as shown in Figure 4.Card
230 top of groove has steam vent 240, and therefore, the position of steam vent 240 is higher than 220 position of air inlet；The steam vent 240 is preferred
The back side positioned at draw-in groove 230, as shown in figure 5, namely positioned at detection lower plate 202 the back side 2022；Certainly, other embodiments
In, steam vent 240 can also be located at the side wall of draw-in groove 230, and be communicated to side wall of detection plate 200 etc..Steam vent 240 and inspection
Drafting board 200 is outer to be connected, and more specifically, the steam vent 240 is connected with urine cup 100 (collecting chamber), positioned at hollow bulb in draw-in groove 230
The gas for dividing is discharged in urine cup 100 by steam vent 240.After liquid enters detection plate 200, the air in detection plate 200
Entered in the hollow space of draw-in groove 230 by air inlet 220, after 230 hollow space of draw-in groove is flowed through, reach steam vent 240, led to
Cross steam vent 240 to be discharged in urine cup 100.
More specifically, include one section of side wall in plane, 122, one section of side wall in cambered surface indent on urine cup sidewall 120
121 and one section of side wall 123 in cambered surface evagination, this three sections of side walls are sequentially connected and connect, and enclose whole urine cup sidewall 120.Inspection
Drafting board 200 is inserted into inner chamber at the side wall 122 of plane, and the cambered surface of the side wall 123 of the side wall 121 and evagination of indent is taken with hand and held
The shape of state fits, and conveniently takes.
In collection and detection device of the present invention 800, including at least one depression on collecting chamber side wall 100, described at least one
Individual depression is located on another connected side wall different from the described side wall in cambered surface indent being connected with flat sidewall 122.Or
Person, collects including at least two depressions in test chamber 100, and at least one depression is located on the side wall in cambered surface indent, at least
There is a depression to be located on another connected side wall different from the described side wall in cambered surface indent being connected with flat sidewall.Specifically
To in the embodiment of urine cup, on urine cup sidewall 120, include two depressions 124；Two depressions 124 are located at 200 institute of detection plate respectively
In the both sides of flat sidewall 122, more specifically, a depression 124 is located on concave side wall 121, neighbouring concave side wall 121 with
122 junction of flat sidewall, another depression 124 are located on convex side wall 123, adjacent plane side wall 122 and convex side wall 123
Junction.The depression 124 for being respectively in 200 plane both sides of detection plate is used for the thumb and forefinger of placement operation person, also, recessed
Falling into 124 and bayonet socket also being formed in urine cup medial wall, be just fixed position detection plate 200 in the inner, detection plate 200 is installed more
Stable.
In some preferred modes, at side depression 124 wherein, can multiple depressions be set thereunder again, be used
Other fingers in placement operation person.
In some improved embodiments, the more analytes in order to realize same sample are disposably detected, Ke Yi
Two-sided (front and reverse side are shown as 200 front of detection plate and install test strips in Fig. 3) engaging test strips are set in detection plate 200,
A dividing plate is set in detection plate, test strips is placed in the positive and negative of dividing plate, on the positive and negative of dividing plate is covered respectively
Plate 201 and lower plate 202, in detection plate 200,210 fluid connection of injection port is to upper plate 201 and the sample of the test strips of lower plate 201
Acceptance region 301, or injection port 210 is respectively provided with upper and lower 201,202 corresponding position of plate of detection plate.Now, draw-in groove 230
(gas channel) can be opened on upper plate 210 and lower plate 202 respectively, it is also possible to which draw-in groove 230 is provided separately within dividing plate；With
Upper type is not intended to limit, and arranges in the way of draw-in groove 230 can realize the function of discharging the air of detection plate；And aerofluxuss
Hole 240 can be opened in the side wall of draw-in groove 230 or the front of draw-in groove, reverse side etc..
In other improved specific embodiments, in order to place more test strips 300, the side wall 120 of urine cup is provided with
The side wall 122 of two planes, is specifically as follows plane 122, concave surface 121, plane 122 and convex surface 123 and is sequentially connected, enclose urine
The side wall 120 of cup.More possible medicines can be examined by 122 position of side wall of two planes equal grafting detection plate 200 simultaneously
Survey.
In other embodiments, the position relationship for urinating the plane 122, concave surface 121 and convex surface 123 of cup sidewall 120 can be with root
According to needing to arrange, such as along counterclockwise, side wall 120 is sequentially plane 122, concave surface 121 and convex surface 123, is relatively suitable for the right side
Hand-held hold.And clockwise, side wall 120 is sequentially plane 122, convex surface 123 and concave surface 121, suitable left hand is taken and is held.
In some embodiments, urine cup 100 and detection plate 200 are made by transparent material, to facilitate the collection of observation sample
Reading of situation and testing result etc..
Specifically used method with regard to the present embodiment urine cup 100 is described below.
Detection plate 200 with multiple test strips for contacting different analytes respectively is inserted in the plane of urine cup 100
At side wall 122, detection plate 200 is connected with draw-in groove 230 by injection port 210 with urine cup 100.
First, whole urine cup device 800 is placed on supporting surface, now, on supporting surface, i.e., the bottom 110 of urine cup is located at
Urine cup device 800 is located at collects position (Fig. 1), opens the lid 400 on urine cup opening 130, collects liquid sample (by urine cup
Opening 130 adds sample), such as urine.
Secondly, (height of the liquid level of general sample less than the 2/3 of urine cup, and sample after the completion of sample collection
Liquid level be not less than urine cup height 1/3), covering lid 400 seals urine cup 100.
3rd, urine cup device 800 is overturn, the concave side wall 121 of urine cup sidewall is turned at supporting surface, as urine cup
The bottom of device 800, i.e. urine cup device 800 are overturn to test position (Fig. 2).
4th, in inspection positions, urine cup 100, liquid sample enters detection plate 200, the sample of sample contact test strips
Detect sample in acceptance region 301, test strips 300.
5th, the testing result in test strips 300 is read, completes to detect.
Claims (12)
1. a kind of collection and detection device, for collecting and detecting fluid sample, including housing detection plate and the collection of testing element
The urine cup of storage fluid sample, detection plate is fully inserted in urine cup, and liquid communication between urine cup, it is characterised in that
Urine cup includes opening, diapire and side wall, includes contact surface on urine cup sidewall；The collection and detection device has collects position and inspection
Location is put, and collection and detection device is in when collecting position, by urine cup bottom wall supports collection and detection device；Collection and detection device is in
During test position, the testing element in collection and detection device, and detection plate is supported perpendicular to contact by the contact surface of urine cup sidewall
Face.
2. collection and detection device according to claim 1, it is characterised in that one end of the nearly urine cup opening of detection plate has to be allowed
Liquid is flowed into the injection port of detection plate from urine cup and allows gas to be flowed into the gas channel of urine cup from detection plate.
3. collection and detection device according to claim 2, it is characterised in that, gas channel includes and detection plate internal cavity
The steam vent that the air inlet being connected is connected with urine cup internal cavity, and connect the excessive liter of the air-flow of air inlet and steam vent
Passage.
4. collection and detection device according to claim 3, it is characterised in that the sample application zone of testing element, sample introduction
The neighbouring contact surface in the position of mouth and air inlet.
5. collection and detection device according to claim 3, it is characterised in that when collection and detection device is located at inspection positions
When, injection port position is not higher than the position of the sample application zone of testing element；Air inlet hole site is higher than injection port position, and enters
Position of the pore position less than testing element marked region.
6. collection and detection device according to claim 1, it is characterised in that the collection and detection device also includes covering simultaneously
The lid of sealing urine cup.
7. collection and detection device according to claim 3, it is characterised in that when detection means is in test position, row
Position of the position of pore higher than air inlet.
8. collection and detection device according to claim 1, it is characterised in that urine cup sidewall have at least one section in cambered surface in
Recessed side wall, when collection and detection device is in test position, the side wall in cambered surface indent is contact surface.
9. collection and detection device according to claim 7, it is characterised in that urine cup sidewall has at least a section in plane
Side wall and at least one section side wall in cambered surface indent；When collection and detection device is in test position, the side wall conduct of cambered surface indent
Contact surface supports collection and detection device, and flat sidewall is perpendicular to horizontal plane.
10. collection and detection device according to claim 1, it is characterised in that urine cup sidewall has one section of side in plane
Wall, one section of side wall and one section of side wall in cambered surface evagination in cambered surface indent, three sections of side walls are sequentially connected and connect, enclose to be formed entirely
Urine cup sidewall；Detection plate is located at the inner chamber body of flat sidewall, and the side wall in cambered surface indent is contact surface.
11. collection and detection devices according to claim 9 or 10, it is characterised in that include at least one on urine cup sidewall
Depression；Depression be located at contact surface be located face in or contact surface to face in.
12. collection and detection devices according to claim 11, it is characterised in that, detection plate is inserted into side of the urine cup in plane
Between wall and the depression.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620948262.5U CN206020428U (en) | 2016-08-26 | 2016-08-26 | A kind of collection and detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201620948262.5U CN206020428U (en) | 2016-08-26 | 2016-08-26 | A kind of collection and detection device |
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| CN206020428U true CN206020428U (en) | 2017-03-15 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI646330B (en) * | 2017-10-20 | 2019-01-01 | 威剛科技股份有限公司 | Liquid detection |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI646330B (en) * | 2017-10-20 | 2019-01-01 | 威剛科技股份有限公司 | Liquid detection |
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