CN206177971U - Collection detection device of fluid sample - Google Patents

Abstract

The utility model relates to a collection detection device of fluid sample for by the analyte in collecting liquid sample and detecting liquid sample, should collect detection device including collecting the chamber, should collect the chamber and enclose to close by bottom and lateral wall and form, the partial lateral wall of collecting the chamber is marginal bellied cardboard, it still includes sealing element to collect detection device, the sealing element lid closes sealed cardboard, forms sealed measuring chamber, one side of cardboard bottom has the introduction port, the introduction port makes to detect the chamber and collect the chamber and is linked together. The device simple structure can adopt blowing manufacturing process, and material cost is low, and, can detect when collecting the sample, can effectively prevent adulteration detection.

Description

A kind of collection and detection device of fluid sample

Technical field

The utility model belongs to medical diagnosis class article technical field, the collection detection of more particularly to a kind of fluid sample Device.

Background technology

Following background technology is used to help reader and understands the present invention, and is not construed as prior art.

At present, general public obtains that forbidden drug is more and more easier, thus forbidden drug use also more and more U.S. HHS's door investigation of 2003 finds that the ratio of drug abuse is up in the American of more than 12 years old 8.2%.With the development of economic society, the ratio of drug abuse gradually increases, and the medicament categories of abuse are also more and more.

Quick detection to Drug Abuses such as drugs typically collects liquid sample using detection means, then by correlation Technical staff's insertion detection strip simultaneously makes the part submergence of detection strip take out strip in the sample, after certain hour and read Testing result.However, in order to be fought with drugs and monitoring drug-taking problem, this test has become a mark when many Quasi-ordering, for example employ, go to school, physical culture, law enforcement etc., operated by amateur testing staff.It is therefore desirable to provide a kind of detection Device, it is to avoid testing staff touches the sample in open liquid collection and detection device, jeopardizes the health of testing staff.Together When, it is also desirable to the collection and detection device can stored samples, sample multiple in the case where there is objection to testing result to facilitate Inspection.Being additionally, since the test of drug abuse has turned into a standardization program, it is also desirable to which this device price is sufficiently minimized, can Meet the demand of large-scale use.

Further, since smoker has the motivation for concealing drug abuse or Drug Abuse, there is sample adulteration； Meanwhile, the substantially species of the medicine that person to be detected is used cannot be accurately estimated before detection, accordingly, it would be desirable to using an inspection Survey device and detect sample adulteration situation and the medicine that the possibility of multiple types is sucked as far as possible simultaneously in one-time detection.

But, existing detection means material cost is high, and assembling is complicated, price, it is impossible to meet the need of large-scale use Ask.

Utility model content

The utility model provides a kind of new collection and detection device, and the apparatus structure is simple, can be manufactured using blowing Technique, the cost of material is low；Further, it is possible to be detected while sample is collected, detection of adulterations can be effectively prevented.

The collection and detection device of a kind of fluid sample provided in the utility model, for collecting liquid sample and detecting liquid Analyte in body sample, wherein, the collection and detection device includes collecting chamber, and the collecting chamber is enclosed and formed by bottom and side wall； The portion outboard wall of the collecting chamber is the clamp of edge protuberance；Collection and detection device also includes potted component, the sealing unit Part covers sealing clamp, forms the test chamber of sealing；The side of the clamp bottom has injection port；The injection port makes detection Chamber is connected with collecting chamber.The edge protuberance of the clamp, makes clamp form groove-like structure.Clamp is used to lay testing element.

Some preferred embodiment in, the potted component be transparent sealing element.When potted component be it is transparent, can be with Clearly observe the detection state and testing result of the testing element in clamp.

Some preferred embodiment in, there is in clamp at least one raised line；The raised line forms one in clamp Or multiple draw-in grooves；The draw-in groove is used to receive testing element.More specifically, draw-in groove is equal in magnitude.

Some preferred embodiment in, on clamp also have gas channel.In one preferred embodiment, gas channel Away from the side of injection port on clamp.

Some preferred embodiment in, the gas channel include convex tendon in the raised side wall of clamp and clamp and Clamp base plate encloses the groove to be formed.

In some specific embodiments, the height of convex tendon is identical with clamp edge protuberance Sidewall Height.

In some specific embodiments, the potted component for sealing clamp equally seals the groove of gas channel, leads to air-flow Road forms sealing.

In some specific embodiments, the height of the height higher than raised line of convex tendon.That is to say, the height of raised line is less than card The height of plate edge protuberance.So, when liquid sample flows in clamp, liquid can cover raised line, be flowed in draw-in groove, But convex tendon can not be being covered, reach gas channel.Some preferred embodiment in, the gas channel by spacing hole with card The draw-in groove fluid of plate is connected；The spacing hole is located on convex tendon.

Some preferred embodiment in, the level height of the level height of spacing hole higher than injection port.Work as liquid sample After being entered in clamp by injection port from collecting chamber, liquid level reaches mouth at spacing hole, is formed in the test chamber of sealing The balance of gas and liquid, so that, liquid is not entered back into clamp cavity.

Some preferred embodiment in, spacing hole horizontal level highly be less than detecting element label pad lower edge.Test unit Part is in detection process, it is only necessary to sample application zone contact sample, and marked region because on carrier with detection Mark substance etc., directly can not contact with liquid, therefore, spacing hole is highly desirable below the lower edge of label pad at position, So as to ensure that liquid level will not have label pad.

Some preferred embodiment in, on gas channel also have steam vent；Steam vent is located on clamp base plate, with receipts Collection chamber is connected.

Some preferred embodiment in, the steam vent horizontal level be higher than spacing hole；The gas is in gas channel Spacing hole and steam vent between flow.

When the gas that liquid sample is entered in test chamber test chambers from collecting chamber by injection port passes through spacing hole, gas Circulation road and steam vent are discharged to collecting chamber, and with the rising of test chamber liquid level, liquid level is raised and floods spacing aperture, and gas cannot Exclude, test chamber reaches vapor liquid equilibrium, the gas on test chamber top prevents liquid sample from going successively to test chamber.

Some preferred embodiment in, between clamp and potted component, also including label card or a label paper.Mark Sign the position of card or label paper on clamp corresponding with the position of testing element, the relevant information for representing testing element, Help operator's recognition detection item.

Some preferred embodiment in, also including close collection chamber lid；After closed with covers collection chamber, entirely Device is in airtight conditions.

Beneficial effect

Collection and detection device simple structure of the invention, can be using blowing manufacturing process, and the cost of material is low.Device assembly Few, equipment step is few, and assembling process only needs to install test-strips and two, sealing detection chamber operation, saves installation time and artificial Cost.Operating procedure is few, after adding sample, starts detection without any operation, it is adaptable to which layman operates, and is also suitable Determined in the batch of extensive sample.Testing result is read soon, and sample detection is started after sample is added, and can rapidly provide inspection Result is surveyed, shortens the stand-by period.The incidence that sample adulteration causes detection to fail is reduced, because sample is once addition Test chamber can be initially entered, starts detection, generally, when subject not yet adds other materials, detection has started to, And because detection needs the amount of sample less, after adding a small amount of sample, air pressure prevents more samples from entering detection in test chamber Chamber, the diluent materials for then adding are less with the situation that testing element reacts, therefore, even if positive sample is mixing diluent There is larger possibility to be detected.

Brief description of the drawings

Fig. 1 is a kind of collection and detection device schematic diagram of the invention；

Fig. 2 is the decomposing schematic representation of collection and detection device of the invention；

Fig. 3 is another decomposing schematic representation of collection and detection device of the invention；

Fig. 4 is the schematic diagram of collection and detection device clamp of the invention；

Fig. 5 is the generalized section of collection and detection device of the invention；

Fig. 6 is another generalized section of collection and detection device of the invention.

Reference：

Collection and detection device 100, collecting chamber 110, test chamber 120, lid 130, clamp 140, raised line 141, gas channel (groove) 142, convex tendon 143, spacing hole 144, draw-in groove 145, injection port 146, clamp edge protuberance 147, steam vent 148, clamp Base plate 149, potted component 150, label card 160, testing element 200

Specific embodiment

Structure of the present invention or these technical terms for being used are described further below.

Detection

" detection " represents chemical examination or tests a kind of material or material whether there is, such as, but be not limited to this, chemicals Matter, organic compound, inorganic compound, metabolism product, medicine or drug metabolite, organic organization or organic organization Metabolin, nucleic acid, protein or polymer.In addition, detection represents the quantity of test substances or material.Furtherly, chemical examination is gone back Represent immune detection, chemical detection, enzyme detection etc..

Testing element (test strips)200

Testing element of the present utility model is applied to for test strips, the horizontal effluent examination that the test strips can be known as Agent bar, the concrete structure and Cleaning Principle of these reagent strips are in the prior art skills known to persons skilled in the art Art.Common reagent strip, as shown in Figure 2 including sample application zone, marked region, detection zone and suction zone, sample connects Included sample pad by region, marked region includes label pad, and suction zone can include adsorptive pads, and detection zone is located at detection film On.Include that the necessary chemical substance containing analyte can be detected whether in detection zone, after detection terminates, can be in detection Occur the detection line and control line that represent result on region.General conventional detection reagent bar is nitrocellulose membrane reagent Bar, i.e. detection zone include nitrocellulose filter (NC films), and specific binding molecule is fixed on nitrocellulose filter to show inspection The end of survey, can also be CAM or nylon membrane etc..The width of usual test strips between 3mm-6mm, one In specific embodiment, the width of test strips is 4mm.

The type of analyte

The example that can be used in the analyte of stable detection of the present invention promotees including (but not only including) human chorionic Gonadal hormone (hCG), lutropin (LH), ovarioestrogen (FSH), hepatitis C virus (HCV), hepatitis B (HBV), hepatitis B The medicine of surface antigen, AIDS virus and any abuse.Analyte can be detected in any liquid or liquefied sample Arrive, for example urine, saliva, blood, blood plasma or serum.The example of other analytes also has the acid of flesh ammonia acid anhydride, bilirubin, nitrous Hydrochlorate, protein (nonspecific), blood, leucocyte, blood sugar, heavy metal and toxin, bacterial component is (for example, particular type Bacterium special protein and sugar, such as colon bacillus 0157:H7, staphylococcus aureus, salmonella, aerogenesis pod Film clostridium, campylobacter, listeria monocytogenes, V. parahaemolyticus, or wax bacillus).Any other suitable side The analyte for flowing test form can be detected with the present apparatus.

The type of sample

Any kind of sample can be tested with device of the invention, including body fluid is (for example, urine and other bodies Liquid, and clinical sample).Fluid sample may originate from solid or semisolid sample, including excrement, biological tissue and food Sample.These solids and semisolid samples can be transformed into fluid sample by any suitable method, such as in one kind Mix in appropriate liquid, stamp broken, macerate, be incubated, dissolving or enzymolysis solid sample (for example, water, phosphate buffer or Other buffer solutions)." biological sample " includes the sample of the animal, plant and food that are derived from living, also including urine, saliva, blood With blood constituent, cerebrospinal fluid, vaginal swab, seminal fluid, excrement, sweat, secretion, tissue, organ, tumour, tissue and organ It is the conditioned media of culture, cell culture and there, either people or animal.Foodstuff samples include finished food Thing composition and last product, meat, cheese, wine, milk and drinking water.Plant sample include be derived from any plant, plant tissue, The sample of the conditioned media of plant cell cultures and there." environmental sample " is that those are derived from the sample of environment (for example, lake water The sample of sample or other water bodys, sewage sample, pedotheque, groundwater sample, seawater sample, the sample of runoff water). The waste of sewage and correlation can also be included in environmental sample.

In the following detailed description, the subsidiary reference word of legend is a part here, and it is illustrating this Utility model can the mode of actable specific concrete scheme illustrate.We are not precluded from the utility model and can also carry out it Its concrete scheme and change structure of the present utility model in the case of without prejudice to use scope of the present utility model.

As shown in figure 1, the collection and detection device 100 of the fluid sample that the utility model is provided, mainly includes collecting chamber 110 Body and the body of test chamber 120 and cover and seal the lid 130 of the two cavitys.Wherein, a part for the body of test chamber 120 is fixed On the body of collecting chamber 110.

Specifically, as shown in Fig. 2 collecting chamber 110 has bottom and side wall to enclose a cavity with one end open, For admitting fluid sample at the opening of cavity.The collecting chamber 110 has the lid 130 supporting with opening, lid 130 on opening After covering at the opening of collecting chamber 110, collecting chamber 110 is closed and sealed.Equally as shown in Figures 2 and 3, the side wall of collecting chamber 110 Predominantly cylinder-like structure, but the side wall of part is the shape structure of clamp 140 wherein, and the four sides edge of the clamp 140 is respectively provided with Outside raised 147, form the side wall of clamp 140, so that clamp 140 forms a big groove type.

The clamp 140 of the groove type is a part for test chamber 120, for disposing testing element.In some embodiments, card There are one or more raised lines 141, some are more specifically in embodiment on the base plate of plate 140, with six raised lines 141；These , by one or more draw-in grooves 145 of the separated place of clamp 140, some are more specifically in embodiment for raised line 141, with seven draw-in grooves 145, These draw-in grooves 145 are used to place and fix testing element, and in a specific embodiment, draw-in groove 145 is used to place detection Test strips.In some preferred modes, the spacing of draw-in groove 145 is identical, and its spacing size is identical with the width of test strips or slightly larger In the width of test strips.

Potted component 150 is coated with clamp 140, the potted component 150 is used to be connect with four edge side walls of clamp 140 Sealing is touched and is formed, so that clamp 140 forms seal cavity a --- body of test chamber 120 of closing.In some embodiments, Potted component 150 is made up of transparent material, so conveniently observes the testing element on clamp 140.Some specific realities Apply in example, potted component 150 is the PVC, PP or transparent plastics etc. of transparent material.

Testing element on clamp 140 needs to touch liquid sample, can just be detected, therefore, on clamp 140 With an opening --- injection port 146, the injection port 146 makes collecting chamber 110 be connected with the cavity formation in clamp 140.More Specifically, injection port 146 makes collecting chamber 110 form fluid connection with the draw-in groove 145 on clamp 140.Some specific embodiments In, in order to realize the sample application zone for making liquid sample release testing element as early as possible, and generally testing element erects placement In clamp 140, sample application zone is located at the bottom of testing element, namely at the bottom of clamp 140, therefore, sample introduction Mouth 146 is located at the bottom position of collecting chamber 110 and clamp 140.Additionally, injection port 146 is located at the bottom of collecting chamber 110, moreover it is possible to Enough realize that sample one enters in the draw-in groove 145 of clamp 140 simultaneously at once after entering in collecting chamber 110, detected as early as possible.One In specific embodiment, injection port 146 is located at the bottom side of clamp 140.

The test chamber 120 of sealing is formed because of potted component 150 and clamp 140, after sample enters test chamber 120, it is necessary to By the portion gas discharge in test chamber 120, to keep the air pressure of test chamber 120.Therefore, it is additionally provided with gas on clamp 140 Gas in the clamp 140 of sealing can be discharged and be transported in collecting chamber 110 by circulation road 142, the gas channel 142.Such as Shown in Fig. 5 and Fig. 6, gas channel 142 be one sealing cavity, concrete structure be have on clamp 140 formed groove 142 with And cover and the potted component 150 of sealed groove 142 is constituted.As shown in Figure 2 and Figure 4, the groove 142 has the side wall of clamp 140 convex Play the 147, bottom of clamp 140 and the convex tendon in clamp 140 143 is enclosed and formed.Wherein, the height of convex tendon 143 and the side of clamp 140 Wall height of projection is identical.

In order that the gas in clamp 140 can enter in gas channel 142, there is spacing hole 144 on convex tendon 143, Gas in clamp 140 enters gas channel 142 by spacing hole 144.At the spacing hole 144 gas can be made to circulate, its The effect that also restricted liquid sample enters in clamp 140, therefore, should be because the body of test chamber 120 in clamp 140 be sealing , liquid sample enters test chamber 120 by injection port 146, and compressing gas is discharged from spacing hole 144, when liquid reaches spacing After at hole 144, formation is also sealed, and now the gas and liquid in cavity reach balance, and liquid does not just enter back into test chamber 120 It is interior, namely do not enter back into clamp 140.The horizontal level of spacing hole 144 is just critically important, can be by the position of spacing hole 144 The liquid level of the liquid that control liquid enters in clamp 140.In some embodiments, the position of spacing hole 144 first is higher than The position of injection port 146, to ensure that enough liquid is detected into clamp 140 is interior；Secondly, the position of spacing hole 144 needs To be less than at the lower edge position of the label pad of testing element, in case liquid directly contacts label pad and influences testing result.One In a little specific embodiments, spacing hole 144 can either discharge gas, the liquid-tight envelope of formation in need, pore size 0.5-2mm it Between.In some specific embodiments, the size of spacing hole 144 is 0.5mm, 0.8mm, 1mm, 1.2mm, 1.5mm, 1.8mm and 2mm。

Gas in gas channel 142 also needs to be discharged, and just can guarantee that the unimpeded of gas channel 142, and one specific In embodiment, there is steam vent 148 at the top of gas channel 142, the steam vent 148 makes gas channel 142 and collecting chamber 110 It is connected.As shown in fig. 6, the steam vent 148 is located on the base plate of clamp 140.In some specific embodiments, steam vent 148 Horizontal level is higher than spacing hole 144；Gas flows between the spacing hole 144 and steam vent 148 of gas channel 142.That is to say Gas enters gas channel 142 from spacing hole 144, from the effluent stream passage 142 of steam vent 148.

In some embodiments, the utility model device 100 also includes label card 160, and the label card 160 is located at potted component Between 150 and clamp 140, it is covered in test strips 200.

Claims (10)

1. a kind of collection and detection device of fluid sample, for collecting liquid sample and detecting analyte in liquid sample, its It is characterised by, the collection and detection device includes collecting chamber, the collecting chamber is enclosed and formed by bottom and side wall；The portion of the collecting chamber Outer side wall is the clamp of edge protuberance；Collection and detection device also includes potted component, and the potted component covers sealing clamp, Form the test chamber of sealing；The side of the clamp bottom has injection port；The injection port makes test chamber be connected with collecting chamber It is logical.

2. collection and detection device according to claim 1, it is characterised in that there is at least one raised line in clamp；It is described Raised line forms at least one draw-in groove in clamp；The draw-in groove is used to receive testing element.

3. collection and detection device according to claim 1, it is characterised in that also there is gas channel on clamp.

4. collection and detection device according to claim 3, it is characterised in that the gas channel includes the raised side of clamp Convex tendon and clamp base plate in wall and clamp enclose the groove to be formed.

5. collection and detection device according to claim 4, it is characterised in that the gas channel passes through spacing hole and clamp Draw-in groove be connected；The spacing hole is located on convex tendon.

6. collection and detection device according to claim 5, it is characterised in that the level height of spacing hole is higher than injection port Level height.

7. collection and detection device according to claim 5, it is characterised in that spacing hole horizontal level is highly less than detection unit Part label pad lower edge.

8. the collection and detection device according to claim 3 or 4, it is characterised in that also there is steam vent on gas channel；Row Stomata is located on clamp, is connected with collecting chamber.

9. collection and detection device according to claim 8, it is characterised in that the steam vent horizontal level is higher than spacing Hole；The gas flows between the spacing hole and steam vent of gas channel.

10. collection and detection device according to claim 1, it is characterised in that also including closing the lid of collection chamber；Lid After son closing collection chamber, whole device is in airtight conditions.