CN205501300U - Cell separation enrichment device - Google Patents

Cell separation enrichment device Download PDF

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Publication number
CN205501300U
CN205501300U CN201620169825.0U CN201620169825U CN205501300U CN 205501300 U CN205501300 U CN 205501300U CN 201620169825 U CN201620169825 U CN 201620169825U CN 205501300 U CN205501300 U CN 205501300U
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CN
China
Prior art keywords
buckle
cell separation
filtrate pipe
enrichment device
filter
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Active
Application number
CN201620169825.0U
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Chinese (zh)
Inventor
方圣云
汪世琼
刘庆友
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Changzhou Zhibo Medical Equipment Co ltd
Original Assignee
Jiangsu Kangbo Medical Devices Co ltd
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Publication date
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Priority to CN201620169825.0U priority Critical patent/CN205501300U/en
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Abstract

The utility model discloses a cell separation enrichment device belongs to medical chemical examination and clinical examination analytical instrument class medical instrument field. The utility model discloses a cell separation enrichment device, including filtering funnel, filter element and filtrate pipe, but the upper end of filtering funnel's lower extreme and filtrate pipe through buckle mechanism split link together, the filter element is installed between filtering funnel and filtrate pipe, buckle mechanism is including the buckle of two relative settings of the flange of locating filtering funnel's cylinder bottom and the body upper end of locating the filtrate pipe, buckle and the mutual lock of flange, and the lower part of buckle is the integrative lever that is used for the unblock buckle that is connected with still. The utility model discloses a mode of membrane is got in the dismouting, has improved filtration membrane's change convenience to has simple structure, convenient operation, small, light in weight, advantage such as not fragile, but wide application in fields such as chemical analysis, bio -pharmaceuticals, sanitary inspection, environmental monitoring, water quality analysis, food and beverage and scientific research.

Description

A kind of cell separation and enrichment device
Technical field
This utility model relates to a kind of cell separation and enrichment device, more particularly, it relates to a kind of circulating tumor cell separation and concentration Device.
Background technology
Circulating tumor cell (circulating tumour cell, CTC) refer to because attack, come off, the inside and outside such as operation technique because of The sanguimotor tumor cell of entrance that element causes.The detection of CTC can be effectively applied to external early diagnosis, chemotherapeutics Rapid evaluation, individualized treatment includes that medicine, the detection of drug resistance, and the exploitation etc. of tumor novel drugs are sieved in Linchuan.At present, CTC Detection means is of a great variety, principle is different.But, owing to circulating tumor cell abundance in peripheral blood is extremely low, about 0.3~100 Individual/ml, differs 4-7 the order of magnitude with leukocyte, and how high efficiency, high-purity ground separate the focus of CTC always research.
Cell separation and enrichment device be circulating tumor cell detection important apparatus, it is desirable to cell separation and enrichment device have corrosion-resistant, The performance such as high temperature resistant and cold-resistant, and require that changeing of filter membrane is convenient and swift, such as, in blood cell filter process, blood The abnormal epithelial cell sample of required extraction can be transferred on filter membrane after filtering by liquid, and the dismounting of filter membrane is the most convenient fast Victory directly influences follow-up Inspection and analysis efficiency.
Summary of the invention
1. utility model to solve the technical problem that
The purpose of this utility model is to provide a kind of cell separation and enrichment device, uses the technical solution of the utility model, passes through Dismounting takes the mode of film, improves the replacing convenience of filter membrane, and has simple in construction, easy to operate, and volume is little, weight Amount is light, the advantage such as is hardly damaged, also can be widely used to chemical analysis, bio-pharmaceuticals, sanitary inspection, environmental monitoring, water quality The fields such as analysis, food and drink and scientific research.
2. technical scheme
For reaching above-mentioned purpose, the technical scheme that this utility model provides is:
A kind of cell separation and enrichment device of the present utility model, including filter funnel, filter element and filtrate pipe, described filtration The lower end of funnel is detachably linked together by snap device with the upper end of filtrate pipe, and described filter element is installed on filtration Between funnel and filtrate pipe.
Further, described snap device includes being located at the flange of the cylinder lower end of filter funnel and being located at the body of filtrate pipe Two buckles being oppositely arranged of upper end, described buckle mutually fastens with flange, and the bottom of described buckle is also connected with For unlocking the lever of buckle.
Further, the cylinder body bottom of described filter funnel is additionally provided with the locating slot for installing filter element.
Further, the side of described locating slot is additionally provided with the breach being easy to grip filter element.
Further, described filter element includes that pad, filter membrane and support ring, described filter membrane are located at pad and are propped up Between pushing out ring, described pad is provided close to the side of cylinder, and described support ring is provided close to the side of body.
Further, the material of described pad is silica gel, and the material of described support ring is PVC.
Further, described filter funnel is PC with the material of filtrate pipe.
3. beneficial effect
The technical scheme using this utility model to provide, compared with existing known technology, has the advantages that
(1) a kind of cell separation and enrichment device of the present utility model, buckle is passed through in the lower end of its filter funnel and the upper end of filtrate pipe Mechanism detachably links together, and filter element is installed between filter funnel and filtrate pipe, uses dismounting to take the mode of film, Improve the replacing convenience of filter membrane, use convenient;
(2) a kind of cell separation and enrichment device of the present utility model, its snap device includes being located at the cylinder lower end of filter funnel Flange and be located at two buckles being oppositely arranged of body upper end of filtrate pipe, buckle mutually fastens with flange, and the bottom of buckle is also It is connected with the lever for unlocking buckle, the simple in construction of snap device, easy to operate, by pressing operation handle Quickly realize the fractionation of filter funnel and filtrate pipe, convenient to use;
(3) a kind of cell separation and enrichment device of the present utility model, the cylinder body bottom of its filter funnel is additionally provided with for installing filtration The locating slot of element, makes filter element easier for installation;Filter element includes pad, filter membrane and support ring, and filter membrane sets Between pad and support ring, pad is provided close to the side of cylinder, and support ring is provided close to the side of body, and filter membrane clamps Sealing closely, in filter process, filter membrane is difficult to contraction distortion, it is ensured that filter effect is good;
(4) a kind of cell separation and enrichment device of the present utility model, the side of its locating slot is additionally provided with to be easy to grip filter element Breach, after arranging this breach, is very easy to the operation with tweezers gripping filter element, takes film more convenient;
(5) a kind of cell separation and enrichment device of the present utility model, its filter funnel is PC with the material of filtrate pipe, has The performances such as corrosion-resistant, high temperature resistant, cold-resistant and insulation;
(6) a kind of cell separation and enrichment device of the present utility model, has volume little, lightweight, the advantage such as is hardly damaged, can It is widely used in chemical analysis, bio-pharmaceuticals, sanitary inspection, environmental monitoring, water analysis, food and drink and scientific research etc. Field.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of cell separation and enrichment device of the present utility model;
Fig. 2 is the fractionation structural representation of a kind of cell separation and enrichment device of the present utility model;
Fig. 3 is the structural representation of the filter funnel in this utility model.
Label declaration in schematic diagram:
1, filter funnel;11, cylinder;12, locating slot;13, flange;14, breach;2, filter element;21, pad; 22, filter membrane;23, support ring;3, filtrate pipe;31, body;32, buckle;33, lever.
Detailed description of the invention
For further appreciating that content of the present utility model, in conjunction with the accompanying drawings and embodiments this utility model is described in detail.
Embodiment
Shown in Fig. 1, a kind of cell separation and enrichment device of the present embodiment, including filter funnel 1, filter element 2 and filter Liquid pipe 3, the lower end of filter funnel 1 is detachably linked together by snap device with the upper end of filtrate pipe 3, filter element 2 It is installed between filter funnel 1 and filtrate pipe 3.Injecting liquid in filter funnel 1, filtrate pipe 3 connects negative pressure device, liquid Body is flowed out by filtrate pipe 3 after filter element 2 filters, and the material in liquid is retained on filter element 2;By filter funnel 1 separates with filtrate pipe 3, can be pulled down by filter element 2, carries out next step operation, uses dismounting to take the mode of film, improves The replacing convenience of filter membrane, uses convenient.
As in figure 2 it is shown, the snap device in the present embodiment includes the flange 13 being located at cylinder 11 lower end of filter funnel 1 and sets In two buckles being oppositely arranged 32 of body 31 upper end of filtrate pipe 3, buckle 32 mutually fastens with flange 13, buckle 32 Bottom be also connected with the lever 33 for unlocking buckle 32;In order to make buckle 32 be more prone at lever 33 Open under pressing effect, buckle 32 can be had resilient connecting rod by one and be connected to the upper end of body 31, and can be On lever 33, anti-slip veins is set, it is simple to lever 33 operates with.The simple in construction of above-mentioned snap device, easy to operate, The fractionation of filter funnel 1 and filtrate pipe 3 can be quickly realized by pressing operation handle 33, convenient to use.Buckle 32 Top is additionally provided with chamfering, when filter funnel 1 assembles with filtrate pipe 3, filter funnel 1 and filtrate pipe 3 is pressed and can make card Button 32 fastens with flange 13.
Additionally, shown in hookup 2, in the present embodiment, be additionally provided with for installing filtering element bottom the cylinder 11 of filter funnel 1 The locating slot 12 of part 2, makes filter element 2 easier for installation;Further, the side at locating slot 12 is additionally provided with and is easy to gripping The breach 14 (as shown in Figure 3) of filter element 2, after using the design of this breach 14, is very easy to filter with tweezers gripping The operation of element 2, takes film more convenient.Filter element 2 includes pad 21, filter membrane 22 and support ring 23, filters Film 22 is located between pad 21 and support ring 23, and pad 21 is provided close to the side of cylinder 11, and support ring 23 is provided close to The side of body 31, filter membrane 22 pinch seal is tight, and in filter process, filter membrane 22 is difficult to contraction distortion, it is ensured that mistake Filter respond well.The material of above-mentioned pad 21 can be silica gel, and the material of support ring 23 can be PVC (polrvinyl chloride), mistake Filter funnel 1 can be all PC (Merlon) with the material of filtrate pipe 3, has the property such as corrosion-resistant, high temperature resistant, cold-resistant and insulation Energy.
A kind of cell separation and enrichment device of the present embodiment, can be used for weak erosive, corrosivity, low-temperature material etc. and filters, pass through Dismounting takes the mode of film, improves the replacing convenience of filter membrane, and has simple in construction, easy to operate, and volume is little, weight Amount is light, the advantage such as is hardly damaged, also can be widely used to chemical analysis, bio-pharmaceuticals, sanitary inspection, environmental monitoring, water quality The fields such as analysis, food and drink and scientific research.
Below being schematically described this utility model and embodiment thereof, this description does not has restricted, shown in accompanying drawing Be also one of embodiment of the present utility model, actual structure is not limited thereto.So, if this area is common Technical staff is enlightened by it, in the case of creating objective without departing from this utility model, without creatively designing and this technology Frame mode that scheme is similar and embodiment, all should belong to protection domain of the present utility model.

Claims (7)

1. a cell separation and enrichment device, it is characterised in that: include filter funnel (1), filter element (2) and filtrate pipe (3), the lower end of described filter funnel (1) is detachably linked together by snap device with the upper end of filtrate pipe (3), Described filter element (2) is installed between filter funnel (1) and filtrate pipe (3).
A kind of cell separation and enrichment device the most according to claim 1, it is characterised in that: described snap device includes setting In filter funnel (1) cylinder (11) lower end flange (13) and be located at filtrate pipe (3) body (31) upper end two The individual buckle (32) being oppositely arranged, described buckle (32) mutually fastens with flange (13), under described buckle (32) Portion is also connected with the lever (33) for unlocking buckle (32).
A kind of cell separation and enrichment device the most according to claim 2, it is characterised in that: described filter funnel (1) Cylinder (11) bottom be additionally provided with the locating slot (12) for installing filter element (2).
A kind of cell separation and enrichment device the most according to claim 3, it is characterised in that: described locating slot (12) Side is additionally provided with the breach (14) being easy to grip filter element (2).
5. according to a kind of cell separation and enrichment device described in Claims 2 or 3 or 4, it is characterised in that: described mistake filtering element Part (2) includes that pad (21), filter membrane (22) and support ring (23), described filter membrane (22) are located at pad (21) And between support ring (23), described pad (21) is provided close to the side of cylinder (11), described support ring (23) It is provided close to the side of body (31).
A kind of cell separation and enrichment device the most according to claim 5, it is characterised in that: the material of described pad (21) Matter is silica gel, and the material of described support ring (23) is PVC.
A kind of cell separation and enrichment device the most according to claim 6, it is characterised in that: described filter funnel (1) It is PC with the material of filtrate pipe (3).
CN201620169825.0U 2016-03-04 2016-03-04 Cell separation enrichment device Active CN205501300U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620169825.0U CN205501300U (en) 2016-03-04 2016-03-04 Cell separation enrichment device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620169825.0U CN205501300U (en) 2016-03-04 2016-03-04 Cell separation enrichment device

Publications (1)

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CN205501300U true CN205501300U (en) 2016-08-24

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107917835A (en) * 2017-12-30 2018-04-17 广州阳普医疗科技股份有限公司 A kind of blood-taking device for screening circulating tumor cell
CN110669637A (en) * 2019-09-29 2020-01-10 北京大学 Fungal spore separation device based on microporous filter membrane, system and separation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107917835A (en) * 2017-12-30 2018-04-17 广州阳普医疗科技股份有限公司 A kind of blood-taking device for screening circulating tumor cell
CN110669637A (en) * 2019-09-29 2020-01-10 北京大学 Fungal spore separation device based on microporous filter membrane, system and separation method thereof

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CP03 Change of name, title or address

Address after: 213012 No. 2188 Longcheng Road, bell tower area, Jiangsu, Changzhou

Patentee after: Changzhou Zhibo Medical Equipment Co.,Ltd.

Address before: 213000 2188 Longcheng Road, Zhong Lou District, Changzhou, Jiangsu

Patentee before: JIANGSU KANGBO MEDICAL DEVICES Co.,Ltd.

CP03 Change of name, title or address