CN107894502A - A kind of detecting device integrated and its method - Google Patents
A kind of detecting device integrated and its method Download PDFInfo
- Publication number
- CN107894502A CN107894502A CN201711113868.2A CN201711113868A CN107894502A CN 107894502 A CN107894502 A CN 107894502A CN 201711113868 A CN201711113868 A CN 201711113868A CN 107894502 A CN107894502 A CN 107894502A
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- CN
- China
- Prior art keywords
- soft bottle
- connector
- plug
- reagent
- sampling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Abstract
The invention discloses a kind of detecting device integrated, including the first soft bottle, the second soft bottle, connector and reagent cup；The outlet end of the first soft bottle is connected with the inlet end of the second soft bottle by connector removable seal, and the inlet end of the outlet end and the reagent cup of the second soft bottle is detachably connected by connector；Also include sampler, the sampling end of the sampler is stretched into the described second soft bottle；The structure of the present invention is simple, it greatly simplify the chromatography testing process of complexity, can be also operable without professional inspection personnel, one device completes all operating processes, reduce consumptive material and cost of labor, ordinary people can detect in family to some conventional projects, be greatly facilitated the convenience of health examination, and social effect is very big.
Description
Technical field
The invention belongs to pattern detection care diagnostic field, more particularly to a kind of detecting device integrated and its method.
Background technology
Chromatography secretion analyte detection needs, reagent detection card, Sample dilution, medical face label, plastic flexible pipe, suction pipe etc.；
Common tertiary hospitals daily tens of sample at least at present, at most more than 500/day, any one step is all very big work
Amount, just take each person-portion reagent detection of drop bottle that 20 dilutions need to be added dropwise, first, being easy to countless Chu adds wrong amount, second, hand holds very much
Change hands sleepiness.Basic hospital is enumerated, basic hospital is not because having professional inspection personnel largely at village level clinic and community medicine machine
Structure does not all carry out conventional detection project, such as bacterium infection or virus infection, these basic detection projects are not all opened during fever
Exhibition, it is most of to be write a prescription with personal experience, big prescription is often resulted in, its reason is that testing reagent operation is excessively complicated, it is impossible to
Once completed inside one system, and easily cause sample contamination；
Existing chromatography detects secretion testing process：Clinical department collecting sample is put into flexible pipe → transport inspection
Section → clinical laboratory, which opens kit taking-up reagent component → opening dilution bottle cap → drop bottle drop 20 is dripped in plastic flexible pipe →, puts
Entering medical face label → mixing repeatedly →, the Sample dilution → instillation reagent mixed with plastic tube suction detects card → reaction 10
Minute → sentence read result.Whole whole testing processes need 1 hour.
The content of the invention
Goal of the invention：In order to overcome the deficiencies in the prior art, the present invention provide it is a kind of detecting device integrated and
Its method, chromatography testing process can be greatly simplified.
Technical scheme：To achieve the above object, it is of the invention a kind of detecting device integrated, including the first soft bottle, second
Soft bottle and reagent cup；The outlet end of the first soft bottle and the inlet end of the second soft bottle are detachably connected by the first connector
Connect, the inlet end of the outlet end and the reagent cup of the second soft bottle is detachably connected by the second connector；Also wrap
Sampler is included, the sampling end of the sampler is stretched into the described second soft bottle.
Further, first connector is ring body structurc, and the first connector both ends are socketed the first soft bottle respectively
Outlet end and the second soft bottle inlet end；
Also including the first plug-hole thing, the first plug-hole thing support is arranged in the range of the enclosing of first connector,
Described first plug-hole thing one end blocks first soft bottle of liquid outlet, and the other end connects the sampler.
Further, in addition to the second connector, the second connector are ring body structurc, the second connector two
End is socketed the outlet end of the second soft bottle and the inlet end of reagent cup respectively；
Also include the second plug-hole thing, the second plug-hole thing support is arranged in the range of the enclosing of the second connector；
One end of the second plug-hole thing blocks second soft bottle of liquid outlet.
Further, the socket of first connector and first soft bottle of outlet end is socketed using screw thread, the first plug-hole
Thing is connected by some first fixed columns and the first connector inwall support, the first plug-hole thing and the first connector inwall it
Between have can pass through the gap of liquid.
Further, the socket of the second connector and second soft bottle of outlet end is socketed using screw thread；Second plug-hole
Thing is connected by some second fixed columns and the second connector inwalls support, and in the second plug-hole thing and the second connector
Liquid can be passed through between wall.
Further, the sampler is quantitative capillary heparin tube, quantitative blood sampling stick, sampling cotton swab or excrement collector；
Capillary on the quantitative capillary heparin tube is sampling end, the sampling end contralateral side on quantitative capillary heparin tube
For connection end；
Sampling circle end on the quantitative sampling rod is sampling end, and the other end is connection end；Wherein sampling circle to be circular or
Oval sampling structure, and sample and be provided with breach or non-notch on circle；
The installation for quantifying blood sampling stick, the first plug-hole thing lower end being installed on using the connection end of face label or excrement collector
Kong Zhong.
Further, strip agent bin vertically is provided with the reagent cup, reagent strip, the reagent is filled with agent bin
Storehouse lower end is provided with reagent Hatch Opening, the sealing of agent bin upper end, has 1 millimeter of -10 milli between the reagent Hatch Opening and reagent cup bottom of a cup
Rice spacing, the observation window surface of the agent bin is plane or cambered surface, and the bottom of a cup of reagent cup is demountable structure.
Further, it is filled with dilution in the described first soft bottle.
Further, a kind of detecting device integrated method, it is specially：
Step 1, collector is removed, collector gathers sample to be detected, reinstalls collector, and device is vertically set
Put；
Step 2, the screw thread socket for unscrewing the first soft bottle and the first connector upwards, the first soft bottle is naturally slowly upper to be lifted, and is made
First plug-hole thing departs from first soft bottle of liquid outlet, and the dilution in the first soft bottle will not be from the presence of surface tension and negative pressure
Liquid outlet flows out, and now the first soft bottle of Manual press, forces the dilution in the first soft bottle to be extruded, and pass through the first connector stream
Enter in the second soft bottle；
Step 3, the second soft bottle is rocked, the sample on dilution and sampler in the second soft bottle is fully mixed, upwards
Unscrew the screw thread socket between the second soft bottle and the second connector, the second soft bottle is naturally slowly upper to be lifted, and departs from the second plug-hole thing
Second soft bottle of liquid outlet, the soft bottle of Manual press the first or the second, the liquid mixed in the second soft bottle is forced to instill reagent cup
In；
Step 4, after standing a period of time, observe the chromatography reaction of the reagent and reagent card in agent bin, and sentence read result.
Beneficial effect：The structure of the present invention is simple, greatly simplify the chromatography testing process of complexity, can be without specialty inspection
It is also operable to test personnel, a device completes all operating processes, and the content that a traditional hour could complete is foreshortened to
12 minutes or so, equipment cost is reduced, ordinary people can detect in family to some conventional projects, be greatly facilitated health
The convenience of physical examination, social effect are very big.
Brief description of the drawings
Accompanying drawing 1 is the schematic diagram of overall structure first of the invention；
Accompanying drawing 2 is the schematic diagram of overall structure second of the invention；
Accompanying drawing 3 is 12 mark partial structural diagrams of accompanying drawing 2；
Accompanying drawing 4 is 13 mark partial structural diagrams of accompanying drawing 2；
The plug-hole thing upward view of accompanying drawing 5 first.
Embodiment
The present invention is further described below in conjunction with the accompanying drawings.
It is a kind of detecting device integrated as shown in Fig. 1 to 5, including the first soft bottle 6, the second soft bottle 3 and reagent cup 2；First
Soft bottle 6 is the soft bottle of elasticity, is specially the materials such as flexible plastic, rubber, barras in the present embodiment, and bottle can pass through injection plus blowing
Mode realize；Fill dilution in first soft bottle 6, the first soft bottle 6 of pressing can make to fill dilution in the first soft bottle 6 from going out liquid
Mouth extrusion；The outlet end of the first soft bottle 6 and the inlet end of the second soft bottle 3 are detachably connected, the second soft bottle 3
The inlet end of outlet end and the reagent cup 2 is detachably connected；Also include sampler 4, the sampling end 15 of the sampler 4
Stretch into the described second soft bottle 3；By dilution, mixing and detection means integration, inspection process is simplified.
Also include the first connector 5, first connector 5 is ring body structurc, and the both ends of the first connector 5 cover respectively
Connect the outlet end of the first soft bottle 6 and the inlet end of the second soft bottle 3；First connector 5 plays sealing and easy-to-dismount work
With；Also include the first plug-hole thing 17, in the present embodiment, the first plug-hole thing 17 with silica gel or similar silica gel by doing sealing-plug material
Material is formed, and the first plug-hole thing 17, which supports, to be arranged in the range of the enclosing of first connector 5, the first plug-hole thing 17
One end blocks first soft bottle of liquid outlet 14, and the other end connects the sampler 4；Sample is diluted, operating process is simple, one
Completed in individual device without branching program, ensure that detection process not by external interference.
Also include the second connector 5.1, in the present embodiment, material is not particularly limited, can for example there are plastics, rubber,
The materials such as resin, second connector 5.1 are ring body structurc, and the both ends of the second connector 5.1 are socketed the second soft bottle 3 respectively
Outlet end and reagent cup 2 inlet end；
Also include the second plug-hole thing 94, the support of the second plug-hole thing 94 is arranged at enclosing for second connector 5.1
In the range of；One end of the second plug-hole thing 94 blocks the second soft liquid outlet of bottle 91.
The socket of the soft outlet end of bottle 6 of first connector 5 and first is socketed using screw thread, in the present embodiment：First
The soft outlet end of bottle 6 of connector 5 and first is provided with sealing ring component in thread bush termination process also on its screw thread, makes its hand
In the case of the dynamic socket that unscrews, the first soft bottle 6 and the external world are also to maintain sealing not on-state, ensure that and are socketed in screw thread
Under the premise of loosening, the first soft bottle 6 of extruding will not gas leakage；
First plug-hole thing 17 is connected by some first fixed columns 20 and the inwall of the first connector 5 support, and first is stifled
The gap 19 of liquid can be passed through by having between the inwall of 17 and first connector of hole thing 5.
The socket of the soft outlet end of bottle 3 of second connector 5.1 and second is socketed using screw thread；Second plug-hole thing 94 is logical
Some second fixed columns 92 are crossed to connect with the inwall of the second connector 5.1 support, and the second plug-hole thing 94 and the second connector
Sample Dilution can be mixed in advance by liquid, the second soft bottle between 5.1 inwalls, make the reagent chromatography detection of next step more accurate
Really.
The sampler 4 is quantitative capillary heparin tube, quantitative blood sampling stick and sampling cotton swab；
Capillary on the quantitative capillary heparin tube is sampling end 15, and the sampling end 15 on quantitative capillary heparin tube is right
Side is connection end；
Sampling circle end on the quantitative sampling rod is sampling end 15, and the other end is connection end；Wherein sampling circle is circle
Or oval sampling structure, and sample and be provided with breach or non-notch on circle；
The connection end of the quantitative capillary heparin tube or quantitative blood sampling stick is installed on the mounting hole of the lower end of the first plug-hole thing 17
In 18.
Strip agent bin 7 vertically is provided with the reagent cup 2, is filled with reagent strip in agent bin 7, under the agent bin 7
End is provided with reagent Hatch Opening, the sealing of the upper end of agent bin 7, has 1 millimeter -10 millimeters between the reagent Hatch Opening and the bottom of a cup 1 of reagent cup 2
Spacing, the observation window surface of the agent bin 7 is plane or cambered surface, and the bottom of a cup 1 of reagent cup 2 is demountable structure.
Dilution is filled with the first soft bottle 6.
A kind of detecting device integrated method, it is specially：
Step 1, collector is removed, collector gathers sample to be detected, reinstalls collector, and device is vertically set
Put；
Step 2, the screw thread socket for unscrewing the first soft connector 5 of bottle 6 and first upwards, the first soft bottle 6 is naturally slowly upper to be lifted,
The first plug-hole thing 17 is set to depart from first soft bottle of liquid outlet 14, effect of the dilution in the first soft bottle 6 in surface tension and negative pressure
Under will not be flowed out from liquid outlet, now the soft bottle 6 of Manual press first, forces the dilution in the first soft bottle 6 to be extruded, and passes through
One connector 5 is flowed into the second soft bottle 3；
Step 3, the second soft bottle 3 is rocked, the sample on dilution and sampler 4 in the second soft bottle 3 is fully mixed, to
On unscrew screw thread socket between the second soft connector 5.1 of bottle 3 and second, the slowly upper lift naturally of the second soft bottle 3, make the second plug-hole
Thing 94 departs from second soft bottle of liquid outlet 91, the manual first or second soft bottle 3, forces the liquid mixed the drop in the second soft bottle 3
Enter in reagent cup 2；
Step 4, after standing a period of time, the chromatography reaction of the reagent and reagent card in agent bin is observed, dilution is from examination
Agent bar bottom chromatography completes antigen-antibody reaction up, according to different several minutes of the rear sentence read results of project.
Described above is only the preferred embodiment of the present invention, it should be pointed out that：For the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (9)
- It is 1. a kind of detecting device integrated, it is characterised in that：Including the first soft bottle (6), the second soft bottle (3) and reagent cup (2)；Institute The outlet end and the inlet end of the second soft bottle (3) for stating the first soft bottle (6) are detachably connected by the first connector (5), institute The connector of inlet end second (5.1) for stating the outlet end and the reagent cup (2) of the second soft bottle (3) is detachably connected；Also Including sampler (4), the sampling end (15) of the sampler (4) is stretched into the described second soft bottle (3).
- 2. one kind according to claim 1 is detecting device integrated, first connector (5) is ring body structurc, described First connector (5) both ends are socketed the outlet end of the first soft bottle (6) and the inlet end of the second soft bottle (3) respectively；Also include the first plug-hole thing (17), the first plug-hole thing (17) support is arranged at enclosing for the first connector (5) In the range of, described first plug-hole thing (17) one end blocks first soft bottle of liquid outlet (14), and the other end connects the sampler (4).
- 3. one kind according to claim 1 is detecting device integrated, it is characterised in that：Second connector (5.1) is Ring body structurc, the second connector (5.1) both ends are socketed the second outlet end of soft bottle (3) and entering for reagent cup (2) respectively Liquid mouth end；Also include the second plug-hole thing (94), the second plug-hole thing (94) support is arranged at enclosing for the second connector (5.1) In the range of conjunction；One end of the second plug-hole thing (94) blocks the second soft bottle (91) liquid outlet.
- 4. one kind according to claim 2 is detecting device integrated, it is characterised in that：First connector (5) and the The socket of one soft bottle (6) outlet end is socketed using screw thread, and the first plug-hole thing (17) passes through some first fixed columns (20) and institute The support connection of the first connector (5) inwall is stated, liquid can be passed through by having between the first plug-hole thing (17) and the first connector (5) inwall The gap (19) of body.
- 5. one kind according to claim 3 is detecting device integrated, it is characterised in that：Second connector (5.1) with The socket of second soft bottle (3) outlet end is socketed using screw thread；Second plug-hole thing (94) by some second fixed columns (92) with Second connector (5.1) the inwall support connection, and can lead between the second plug-hole thing (94) and the second connector (5.1) inwall Cross liquid.
- 6. one kind according to claim 1 or 2 is detecting device integrated, it is characterised in that：The sampler (4) is quantitative Capillary heparin tube, quantitative blood sampling stick, sampling cotton swab and excrement collector；Capillary on the quantitative capillary heparin tube is sampling end (15), and the sampling end (15) on quantitative capillary heparin tube is right Side is connection end；Sampling circle end on the quantitative sampling rod is sampling end (15), and the other end is connection end；Wherein sampling circle to be circular or Oval sampling structure, and sample and be provided with breach or non-notch on circle；The quantitative capillary heparin tube, quantitative blood sampling stick, signed using face, the connection end of excrement collector is installed on the first plug-hole thing (17) in the mounting hole (18) of lower end.
- 7. one kind according to claim 1 is detecting device integrated, it is characterised in that：Vertically set in the reagent cup (2) There is strip agent bin (7), reagent strip is filled with agent bin (7), agent bin (7) lower end is provided with reagent Hatch Opening, agent bin (7) upper end seals, and has 1 millimeter of -10 millimeters of spacing, the agent bin between the reagent Hatch Opening and reagent cup (2) bottom of a cup (1) (7) observation window surface is plane or cambered surface, and the bottom of a cup (1) of reagent cup (2) is demountable structure.
- 8. one kind according to claim 1 is detecting device integrated, it is characterised in that：Filled in the first soft bottle (6) There is dilution.
- A kind of 9. detecting device integrated method, it is characterised in that：Step 1, collector is removed, collector gathers sample to be detected, reinstalls collector, and make device vertically arranged；Step 2, the screw thread for unscrewing the first soft bottle (6) and the first connector (5) upwards are socketed, on the first soft bottle (6) is naturally slow Lift, the first plug-hole thing (17) is set to depart from first soft bottle of liquid outlet (14), the dilution in the first soft bottle (6) is in surface tension and negative It will not be flowed out in the presence of pressure from liquid outlet, now the first soft bottle of Manual press (6), force the dilution in the first soft bottle (6) Extrusion, and flowed into by the first connector (5) in the second soft bottle (3)；Step 3, the second soft bottle (3) is rocked, the sample on dilution and sampler (4) in the second soft bottle (3) is fully mixed, Unscrew the screw thread socket between the second soft bottle (3) and the second connector (5.1) upwards, the second soft bottle (3) is naturally slowly upper to lift, and makes Second plug-hole thing (94) departs from second soft bottle of liquid outlet (91), the soft bottle of Manual press the first or the second (3), forces the second soft bottle (3) liquid mixed in is instilled in reagent cup (2)；Step 4, after standing a period of time, observe the chromatography reaction of the reagent and reagent card in agent bin, and sentence read result.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711113868.2A CN107894502B (en) | 2017-11-13 | 2017-11-13 | Integrated detection device and method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711113868.2A CN107894502B (en) | 2017-11-13 | 2017-11-13 | Integrated detection device and method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107894502A true CN107894502A (en) | 2018-04-10 |
| CN107894502B CN107894502B (en) | 2020-07-24 |
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ID=61805209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711113868.2A Active CN107894502B (en) | 2017-11-13 | 2017-11-13 | Integrated detection device and method thereof |
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| Country | Link |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108627364A (en) * | 2018-08-08 | 2018-10-09 | 江苏宝卫士生物科技有限公司 | A kind of medical agent detection device |
| CN113167797A (en) * | 2018-11-27 | 2021-07-23 | 韩国帕克特生物科技有限公司 | Tuberculosis diagnosis method and apparatus therefor |
| CN113791210A (en) * | 2021-09-17 | 2021-12-14 | 石家庄洹众生物科技有限公司 | Reagent strip and device for simultaneously detecting matrix metalloproteinase-8 and interleukin-6 and application thereof |
| WO2023102382A1 (en) * | 2021-11-30 | 2023-06-08 | Emed Labs, Llc | Lateral flow test kits |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103154735A (en) * | 2009-05-11 | 2013-06-12 | 连接Dx股份有限公司 | Methods and compositions for analyte detection |
-
2017
- 2017-11-13 CN CN201711113868.2A patent/CN107894502B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103154735A (en) * | 2009-05-11 | 2013-06-12 | 连接Dx股份有限公司 | Methods and compositions for analyte detection |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108627364A (en) * | 2018-08-08 | 2018-10-09 | 江苏宝卫士生物科技有限公司 | A kind of medical agent detection device |
| WO2020029343A1 (en) * | 2018-08-08 | 2020-02-13 | 江苏宝卫士生物科技有限公司 | Medical reagent detecting device |
| CN113167797A (en) * | 2018-11-27 | 2021-07-23 | 韩国帕克特生物科技有限公司 | Tuberculosis diagnosis method and apparatus therefor |
| EP3889608A4 (en) * | 2018-11-27 | 2022-09-07 | Boditech Med Inc. | Tuberculosis diagnosis method and apparatus therefor |
| CN113791210A (en) * | 2021-09-17 | 2021-12-14 | 石家庄洹众生物科技有限公司 | Reagent strip and device for simultaneously detecting matrix metalloproteinase-8 and interleukin-6 and application thereof |
| WO2023102382A1 (en) * | 2021-11-30 | 2023-06-08 | Emed Labs, Llc | Lateral flow test kits |
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| Publication number | Publication date |
|---|---|
| CN107894502B (en) | 2020-07-24 |
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