CN108627364A - A kind of medical agent detection device - Google Patents

A kind of medical agent detection device Download PDF

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Publication number
CN108627364A
CN108627364A CN201810897715.XA CN201810897715A CN108627364A CN 108627364 A CN108627364 A CN 108627364A CN 201810897715 A CN201810897715 A CN 201810897715A CN 108627364 A CN108627364 A CN 108627364A
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CN
China
Prior art keywords
liquid
bottle cap
plug
hole object
bottles
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CN201810897715.XA
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Chinese (zh)
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CN108627364B (en
Inventor
刘元
吴国荣
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Jiangsu Bao Bao Biological Technology Co Ltd
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Jiangsu Bao Bao Biological Technology Co Ltd
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Priority to CN201810897715.XA priority Critical patent/CN108627364B/en
Priority to PCT/CN2018/102902 priority patent/WO2020029343A1/en
Publication of CN108627364A publication Critical patent/CN108627364A/en
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Publication of CN108627364B publication Critical patent/CN108627364B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Hydrology & Water Resources (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of medical agent detection device, including sample collection stick and liquid bottles, the outlet end of the liquid bottles is removably connected with bottle cap;One end of the sample collection stick is sampling end, and the other end is connected with plug-hole object;The plug-hole object integration is detachably connected in bottle cap, and the plug-hole object surrounding can flow through liquid;The structure of the present invention is simpler compared with traditional agent detection devices, only needs three components, soft bottle can be used as dilution storage chamber can use again as mixing sample, simplify traditional three stage structure, simplify operating process;When bottle cap is tightened on the outlet end of the liquid bottles, the silica gel sealing pad on sealing surface described in sealing ring or seal ring seal top pressure, sealing performance more consolidates.

Description

A kind of medical agent detection device
Technical field
The invention belongs to reagent detection field more particularly to a kind of medical agent detection devices.
Background technology
Drop bottle is medical treatment consumptive materials, and using very extensive, but existing drop bottle, when feces collection is diluted and is loaded, liquid outlet is necessary Add bottle cap or liquid outlet channel to add at frangibility, existing Drop-bottle cap often because dismantle it is lower after put the due to of rolling on the table and look for not It arrives, can not restore after fractureing at another way frangibility, sample can not be retained, and hospital needs to retain sample after 3 days at ability Reason, so use inconvenience.
Intestinal cancer and gastric cancer are 5 big tumours before China, and China is because of annual dead 37.6 ten thousand people of intestinal cancer, because of mortality of gastric carcinoma 800,000 People, one of the main reasons for this is that early detection can not be early diagnosed, stool examination feces occult blood and stomach Helicobacter pylori antigen are The two indices of screening intestinal cancer and gastric cancer world health organisation recommendations, but the private medical center in China and 90% or more Hospital Physical Examination Inspection is abandoned in excrement detection, is acquired the main reason is that sample is bad, bad transport, is operated foul smelling smell, is inconvenient for operation, big portion People is unwilling that acquire excrement checks to hospital.Have become global problem.
Existing drop bottle is because being to dismantle drop bottle liquid outlet bottle cap or the liquid outlet that fractures from external frangibility from outside, and connect Detection cup needs liquid outlet being connected in detection cup, is rolled over from outside dismounting liquid outlet bottle cap and from external frangibility after connection Disconnected liquid outlet can not operate.It can not be from feces collection, mixing, sample-adding, detection integration.
Invention content
Goal of the invention:In order to overcome the deficiencies in the prior art, the present invention to provide a kind of simple in structure, good airproof performance A kind of medical agent detection device.
Technical solution:To achieve the above object, a kind of medical agent detection device of the invention, including sample collection stick and The outlet end of liquid bottles, the liquid bottles is removably connected with bottle cap;One end of the sample collection stick is sampling end, another End is connected with plug-hole object;The plug-hole object integration is detachably connected in bottle cap, and the plug-hole object surrounding can flow through liquid Body;
When bottle cap is tightened on the outlet end of the liquid bottles, the sealing of plug-hole object blocks the liquid outlet of liquid bottles, and sample The sampling end of acquisition rod stretches into the bottle chamber of the liquid bottles;
When the outlet end of liquid bottles is unscrewed, plug-hole object detaches bottle cap with the liquid outlet of liquid bottles, the liquid in liquid bottles Body passes through from plug-hole object surrounding.
Further, further include reagent reacting cup, the rim of a cup of the reagent reacting cup is integrated or is detachably connected described Bottle cap, from the plug-hole object surrounding by liquid flow into the reagent reacting cup.
Further, the bottom of the plug-hole object is provided with several pillars, and the gap between adjacent two pillar can pass through Liquid;
Block machine is provided in the bottle cap, the end of each pillar contacts face where the block machine, set in the block machine It is equipped with liquid-leaking nozzle, the liquid flowed out from the gap between adjacent two pillar is flowed by liquid-leaking nozzle in reagent reacting cup.
Further, the outlet end bottle mouth position protrusions of the liquid bottles are provided with sealing ring or sealing ring;The plug-hole object It is provided with silica gel sealing pad on the sealing surface of liquid bottles side, when bottle cap is tightened on the outlet end of the liquid bottles, Silica gel sealing pad on sealing surface described in sealing ring or seal ring seal top pressure.
Further, the liquid bottles are soft bottle.
Further, there is rib on the surrounding wall body on the plug-hole object or bottle cap inner wall, liquid is formed between consecutive web Body passes through slot.
Optionally, the bottle cap is that lower end may be provided with the dropping liquid bottle cap of liqiud outlet head, from the plug-hole object surrounding by Liquid is flowed out by bottle cap for lower end liqiud outlet head.
Advantageous effect:The present invention, which is applied to drop bottle, can solve drop bottle liquid outlet bottle cap and easily look for loseing to fracture at frangibility The problem of liquid outlet can not restore need to only unscrew after bottle cap (bottle cap is with liquid bottles without separating), squeeze soft bottle and liquid be added dropwise, It is added dropwise after the completion of liquid and tightens bottle cap, perfectly solve external liquid outlet bottle cap and easily look for and lose and to go out liquid at frangibility logical The problem of road can not restore.
Present invention can also apply to connecting detection cup, need to only unscrew after bottle cap (bottle cap is with liquid bottles without separating), The problem of detection cup can be flowed by squeezing soft bottle liquid, and the existing product solved well encounters.It is applied to feces occult blood and stomach is deep and remote Door pylori antigen fecal sample detection can make fecal sample acquisition, dilution, mixing, sample-adding, detection integration, and complete " locked in " operation, odorlessness.So be individual be in can screening intestinal cancer and gastric cancer people at highest risk, social effect it is great.
Description of the drawings
Attached drawing 1 is overall structure diagram when bottle cap lower end connects reagent reacting cup;
This patent integral demounting schematic diagram that attached drawing 2 is bottle cap when being dropping liquid bottle cap;
Attached drawing 3 is the dismounting schematic diagram of attached drawing 1;
Attached drawing 4 is fluid present invention bottle bottleneck partial structural diagram;
Attached drawing 5 splits structural schematic diagram for attached drawing 4;
Attached drawing 6 is acquisition rod structural schematic diagram;
Attached drawing 7 is reagent reacting cup structural schematic diagram.
Specific implementation mode
The present invention is further described below in conjunction with the accompanying drawings.
A kind of medical agent detection device as shown in attached drawing 1 to 7, including sample collection stick 2 and liquid bottles 1, the liquid The outlet end 1.1 of body bottle 1 is removably connected with bottle cap 3;One end of the sample collection stick 2 is sampling end 4, and the other end is connected with Plug-hole object 5;5 integration of the plug-hole object is detachably connected in bottle cap 3, and 5 surrounding of plug-hole object can flow through liquid;
When bottle cap 3 is tightened on the outlet end 1.1 of the liquid bottles 1, the sealing of plug-hole object 5 blocks the liquid outlet of liquid bottles 1 12, and the sampling end 4 of sample collection stick 2 stretches into the bottle chamber 7 of the liquid bottles 1;Bottle cap 3 is screwed in the outlet end 1.1 of liquid bottles 1 Song Shi, plug-hole object 5 are detached with the liquid outlet 12 of liquid bottles 1, and the liquid in liquid bottles 1 passes through from 5 surrounding of plug-hole object.
The embodiment of the first product is as shown in Figure 1, further include reagent reacting cup 6, the rim of a cup one of the reagent reacting cup 6 Body is detachably connected the bottle cap 3, from 5 surrounding of plug-hole object by liquid flow into the reagent reacting cup 6;The The implementation of two kinds of products such as Fig. 2,3 lower end of bottle cap can also be not provided with reagent reacting cup 6 in the present embodiment, but under bottle cap 3 End is directly arranged liquid droping head, 5 surrounding of plug-hole object by liquid pass through the outflow of the liquid droping head 90 of 3 lower end of bottle cap;
The bottom of the plug-hole object 5 is provided with several pillars 11, and the gap 10 between adjacent two pillar 11 can pass through liquid Body;Block machine 20 is provided in the bottle cap 3, the end of each pillar 11 contacts the 20 place face of block machine, the block machine 20 On be provided with liquid-leaking nozzle 21, between adjacent two pillar 11 gap 10 flow out liquid pass through liquid-leaking nozzle 21 flow into reagent reaction In cup 6.
The 1.1 bottle mouth position protrusion of outlet end of the liquid bottles 1 is provided with sealing ring 9 or sealing ring;The plug-hole object 5 is close Silica gel sealing pad is provided on the sealing surface 5.1 of 1 side of liquid bottles, bottle cap 3 is tightened on the outlet end 1.1 of the liquid bottles 1 When, the silica gel sealing pad on sealing surface 5.1 described in sealing ring 9 or seal ring seal top pressure.
Liquid bottles 1 in the present embodiment are soft bottle, if since the dilution in the application fluids bottle 1 of atmospheric pressure does not flow out, Outflow can be forced by squeezing liquid bottles 1;It is evenly equipped with rib 15 on surrounding wall body on 3 inner wall of the plug-hole object 5 or bottle cap, Liquid is formed between consecutive web 15 by slot 13, which can flow through liquid by slot 13.
The operating process and portion of techniques progress of the present apparatus are as follows:
Application case when bottle cap 3 is dropping liquid bottle cap:
Such as Fig. 2,1 inner cavity of liquid bottles is precharged with diluent liquid, dismounting bottle cap 3 and liquid bottles 1, holds bottle cap 3, adopt at this time It is equivalent to and is connected on bottle cap 3 with stick 8, from sampling, sampling rod 8 is reentered into liquid bottles 1 after 8 collecting samples, tightens bottle Lid 8 makes bottle cap 8 be tightly connected with liquid bottles 1, and rocking liquid bottles 1 makes sample and dilution mixing, unclamps bottle cap 8 and liquid bottles 1 (bottle cap 8 does not detach with liquid bottles 1) squeezes liquid bottles 1, and liquid is by 5 surrounding cocurrent liqiud outlet head 90 of plug-hole object, required for being added drop-wise to Reagent on.
3 lower end of bottle cap connects application case when reagent reacting cup 6:
Bottle cap 3 is integrated with reagent reacting cup 6, and 1 inner cavity of liquid bottles is precharged with diluent liquid, dismantles bottle cap and liquid Bottle holds bottle cap, is connected to reaction cup on bottle cap using stick, sampling rod is put into liquid bottles after sampling rod collecting sample It is interior, bottle cap is tightened, bottle cap is made to be tightly connected with liquid bottles, rocking liquid bottles makes sample and dilution mixing, unclamps bottle cap and liquid Body bottle (bottle cap does not detach with liquid bottles) squeezes soft bottle, and liquid flows out liquid outlet by sampling rod surrounding, and it is anti-that liquid enters reagent It answers in cup 6.
Detailed process is as follows:
1 inner cavity of liquid bottles is pre-filled with diluent liquid in the present embodiment, and the present apparatus is vertically stood upside down, liquid bottles 1 are made Outlet end 1.1 upward, then screws the cap off a bottle 3, and then acquisition rod 2 is detached from liquid bottles 1 with bottle cap 3, is then adopted with sample collection stick 2 Collect blood or fecal specimens, after the sampling end 4 of sample collection stick 2 is stretched into again in liquid bottles 1, and tighten bottle cap 3 again, make The sealing of sealing surface 5.1 on plug-hole object 5 blocks the sealing ring 9 of 1 outlet end of liquid bottles, 1.1 bottle mouth position, then that the present apparatus is vertical Upright, the outlet end 1.1 for making liquid bottles 1 downward, fully shakes up liquid bottles 1, after standing a period of time, unclamps going out for liquid bottles 1 The threaded connection at liquid end 1.1 makes the sealing surface 5.1 on plug-hole object 5 be detached from the sealing ring 9 of 1 outlet end of liquid bottles, 1.1 bottle mouth position, And then the liquid in liquid bottles 1 is made to pass through from 5 surrounding of plug-hole object, and then it is anti-by the liquid-leaking nozzle 21 in block machine 20 to flow out to reagent It answers in cup 6, if the effect dilution due to atmospheric pressure does not flow out, outflow can be forced by squeezing liquid bottles 1;It is then allowed to stand 10 After or so minute, the chromatography reaction of the reagent and reagent card in reagent reacting cup 6, and sentence read result are observed.
As shown in fig. 7, being provided with partition board 6.3 in the reagent reacting cup 6 of the present embodiment along the longitudinal direction, partition board 6.3 will try Cavity in agent reaction cup 6 is divided into admission chamber 6.1 and test paper accommodating chamber 6.2,6.1 upper end of the admission chamber to be connected to liquid-leaking nozzle 21,6.1 lower end of the admission chamber is connected to 6.2 lower end of test paper accommodating chamber;Appearance can be filled in the test paper accommodating chamber 6.2 of the present embodiment Receive test paper, the sampled point of wherein test paper is arranged downward;The bottom 6.4 of the reagent reacting cup 6 of the present embodiment is detachable structure;This Sample liquid body is flowed into the lower end that test paper accommodating chamber 6.2 is flowed into behind the bottom of admission chamber 6.1 by liquid-leaking nozzle 21, and then is sent out with test paper Generating layer analysis reaction.
The above is only a preferred embodiment of the present invention, it should be pointed out that:For the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (7)

1. a kind of medical agent detection device, it is characterised in that:Including sample collection stick (2) and liquid bottles (1), the liquid bottles (1) outlet end (1.1) is removably connected with bottle cap (3);One end of the sample collection stick (2) is sampling end (4), the other end It is connected with plug-hole object (5);Plug-hole object (5) integration is detachably connected in bottle cap (3), and the plug-hole object (5) four Week can flow through liquid;
When bottle cap (3) is tightened on the outlet end (1.1) of the liquid bottles (1), plug-hole object (5) sealing blocks liquid bottles (1) Liquid outlet (12), and the sampling end (4) of sample collection stick (2) stretches into the bottle chamber (7) of the liquid bottles (1);
Bottle cap (3) is when the outlet end (1.1) of liquid bottles (1) is unscrewed, the liquid outlet (12) of plug-hole object (5) and liquid bottles (1) It detaches, the liquid in liquid bottles (1) passes through from plug-hole object (5) surrounding.
2. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:Further include reagent reacting cup (6), The rim of a cup integration of the reagent reacting cup (6) is detachably connected the bottle cap (3), passes through from plug-hole object (5) surrounding Liquid flow into the reagent reacting cup (6).
3. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:The bottom of the plug-hole object (5) Several pillars (11) are provided with, the gap (10) between adjacent struts (11) can pass through liquid;
Block machine (20) is provided in the bottle cap (3), the end of each pillar (11) contacts face where the block machine (20), institute It states and is provided with liquid-leaking nozzle (21) in block machine (20), the liquid flowed out from the gap (10) between adjacent two pillar (11) passes through leakage Hole (21) flows into reagent reacting cup (6).
4. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:The liquid bottles (1) go out liquid End (1.1) bottle mouth position protrusion is provided with sealing ring (9) or sealing ring;Sealing of the plug-hole object (5) close to liquid bottles (1) side Silica gel sealing pad is provided on face (5.1), when bottle cap (3) is tightened on the outlet end (1.1) of the liquid bottles (1), sealing ring (9) or the silica gel sealing pad on sealing surface (5.1) described in seal ring seal top pressure.
5. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:The liquid bottles (1) are soft bottle.
6. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:The plug-hole object (5) or bottle cap (3) there is rib (15) on the surrounding wall body on inner wall, forming liquid between consecutive web (15) passes through slot (13).
7. according to a kind of medical agent detection device shown in claim 1, it is characterised in that:The bottle cap (3) is that lower end can Be provided with the dropping liquid bottle cap of liqiud outlet head (90), from plug-hole object (5) surrounding by liquid be by bottle cap (3) under bring out liquid Head (90) outflow.
CN201810897715.XA 2018-08-08 2018-08-08 Medical reagent detection device Active CN108627364B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201810897715.XA CN108627364B (en) 2018-08-08 2018-08-08 Medical reagent detection device
PCT/CN2018/102902 WO2020029343A1 (en) 2018-08-08 2018-08-29 Medical reagent detecting device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810897715.XA CN108627364B (en) 2018-08-08 2018-08-08 Medical reagent detection device

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CN108627364A true CN108627364A (en) 2018-10-09
CN108627364B CN108627364B (en) 2024-06-07

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WO (1) WO2020029343A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020029343A1 (en) * 2018-08-08 2020-02-13 江苏宝卫士生物科技有限公司 Medical reagent detecting device
CN112316997A (en) * 2020-11-23 2021-02-05 蔡竹 Combined sample collection and detection device and sampling tube and detection tube thereof
CN114778210A (en) * 2022-06-24 2022-07-22 国家海洋技术中心 Water storage tank, multi-point automatic water sampling device and method

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US20090005705A1 (en) * 2007-06-28 2009-01-01 John Wan Fecal Specimen Collector
CN205826330U (en) * 2016-06-30 2016-12-21 益思美诠生物科技(上海)有限公司 Integral type fecal specimens collecting and detecting device
CN107894502A (en) * 2017-11-13 2018-04-10 江苏宝卫士生物科技有限公司 A kind of detecting device integrated and its method
CN207541079U (en) * 2017-12-14 2018-06-26 江苏宝卫士生物科技有限公司 A kind of reagent bottle for medical test penetrates through switch
CN207541084U (en) * 2017-11-13 2018-06-26 江苏宝卫士生物科技有限公司 A kind of liquid supply structure of medicine detection
CN207636605U (en) * 2017-11-13 2018-07-20 江苏宝卫士生物科技有限公司 A kind of filtering perforation switch for medicine detection

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US10369572B2 (en) * 2015-07-31 2019-08-06 Point Of Care Diagnostics, Llc Reagent dispensing apparatus
CN206161341U (en) * 2016-10-31 2017-05-10 江苏景润医疗器械有限公司 Excrement collecting device
CN108627364B (en) * 2018-08-08 2024-06-07 江苏宝卫士生物科技有限公司 Medical reagent detection device
CN208476578U (en) * 2018-08-08 2019-02-05 江苏宝卫士生物科技有限公司 A kind of medical agent detection device

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US20090005705A1 (en) * 2007-06-28 2009-01-01 John Wan Fecal Specimen Collector
CN205826330U (en) * 2016-06-30 2016-12-21 益思美诠生物科技(上海)有限公司 Integral type fecal specimens collecting and detecting device
CN107894502A (en) * 2017-11-13 2018-04-10 江苏宝卫士生物科技有限公司 A kind of detecting device integrated and its method
CN207541084U (en) * 2017-11-13 2018-06-26 江苏宝卫士生物科技有限公司 A kind of liquid supply structure of medicine detection
CN207636605U (en) * 2017-11-13 2018-07-20 江苏宝卫士生物科技有限公司 A kind of filtering perforation switch for medicine detection
CN207541079U (en) * 2017-12-14 2018-06-26 江苏宝卫士生物科技有限公司 A kind of reagent bottle for medical test penetrates through switch

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020029343A1 (en) * 2018-08-08 2020-02-13 江苏宝卫士生物科技有限公司 Medical reagent detecting device
CN112316997A (en) * 2020-11-23 2021-02-05 蔡竹 Combined sample collection and detection device and sampling tube and detection tube thereof
CN114778210A (en) * 2022-06-24 2022-07-22 国家海洋技术中心 Water storage tank, multi-point automatic water sampling device and method

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