CN205449605U - Cell slide processing machine - Google Patents

Cell slide processing machine Download PDF

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Publication number
CN205449605U
CN205449605U CN201620007762.9U CN201620007762U CN205449605U CN 205449605 U CN205449605 U CN 205449605U CN 201620007762 U CN201620007762 U CN 201620007762U CN 205449605 U CN205449605 U CN 205449605U
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China
Prior art keywords
cell chip
film
preparing machine
rotating disk
putting hole
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CN201620007762.9U
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Chinese (zh)
Inventor
夏炜
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Beijing Chengzhi Guanghui Technology Co Ltd
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Beijing Chengzhi Guanghui Technology Co Ltd
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Priority to CN201620007762.9U priority Critical patent/CN205449605U/en
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Abstract

The utility model discloses a cell slide processing machine, its technical scheme main points are: which comprises a base, be provided with the carousel on the base, the periphery of carousel is provided with a plurality of stationary blades, forms the draw -in groove between the adjacent stationary blade, be provided with dress liquid pelleter in the draw -in groove and construct, be provided with the first second of placing the hole and supplying the pipette to place that supplies the test tube to place on the stationary blade and place the hole, still be equipped with on the base and be used for snatching the moving mechanism that the pipette was absorb liquid and was removed. The utility model provides a current liquid -based thin -layer cell film -making device function problem single relatively.

Description

Cell chip preparing machine
Technical field
This utility model relates to biomedicine field, and in particular, it relates to a kind of cell chip preparing machine.
Background technology
Fast development and the raising of the level of economic development along with pathology technique so that the application in pathological diagnosis, the especially preparation of cytopathology specimen of the second filial generation liquid-based cell sample manufacturing technology with decanter type liquid-based cell sample manufacturing technology as representative is more and more extensive.Compared with traditional manual smear technique, decanter type liquid-based cell sample manufacturing technology solves film-making background subtraction, cell distribution is uneven, lose the critical defects such as masculine principle, it is reported that, for the recall rate of cytology's positive sample (HISL+), use " U.S. surpasses cypress decanter type liquid-based cell sample manufacturing technology (LCT) " 64.4% can be improved than conventional manual method.
In prior art, the Chinese patent of Application No. 201520522044.0 discloses a kind of Thinprep pap test pelletizer, and it includes rotating centrifugal mechanism and the some Zhuan Ye producer agencies setting up separately on rotating centrifugal mechanism outer circumferential side;Described Zhuan Ye producer agency is hinged with rotating centrifugal mechanism, and jointed shaft is perpendicular to the line between Zhuan Ye producer agency center of gravity and rotating centrifugal mechanism rotary shaft;Described Zhuan Ye producer agency includes firm banking and is vertically plugged on the filter tube on firm banking top, the bottom of described firm banking is provided with horizontally extending slide insertion groove, and the top of firm banking is provided with the body insert port matched with filter tube lower end, described body insert port is connected with slide insertion groove, and described filter tube bottom is provided with cushion rubber.
During sectioning cells, generally require and first blood is centrifuged, difference according to all kinds of hemocyte proportions, utilize proportion cell separation liquid between certain two class cell to centrifugal blood, the hemocyte making certain weight proportion is distributed in different free bands according to corresponding density gradient, thus reaches the purpose separated.After releasing, need to draw by the waste liquid on upper strata, the most again the cell of lower floor is drawn out film-making.And above-mentioned Thinprep pap test pelletizer can only reach and the cell drawn out is directly being carried out film-making, centrifugal and film-making process cannot be carried out on the same device.
Utility model content
The deficiency existed for prior art, the purpose of this utility model is to provide a kind of cell chip preparing machine, and it can not only realize sectioning cells, additionally it is possible to realizes the centrifugal of blood.
For achieving the above object, this utility model provides following technical scheme: a kind of cell chip preparing machine, including pedestal, it is provided with rotating disk on described pedestal, the periphery of described rotating disk is provided with some stators, forms draw-in groove, be provided with Zhuan Ye producer agency in described draw-in groove between adjacent stator, it is provided with the first putting hole placed for test tube and the second putting hole placed for pipet on stator, described pedestal is additionally provided with the travel mechanism for capturing pipette, extract liquid movement.
By using technique scheme, blood is placed in vitro, then test tube is placed in the first putting hole, being then centrifuged for, after centrifugal end, travel mechanism moves crawl pipet and draws upper strata waste liquid in test tube, then the cell of bottom is drawn in second time action, the cell of absorption is put in Zhuan Ye producer agency, carry out film-making, this makes it possible to complete centrifugal and film-making the most simultaneously.
Preferably, described first putting hole and described second putting hole being radially arranged along described rotating disk, described first putting hole and described Zhuan Ye producer agency are arranged on same circumference, and described travel mechanism includes the radial slippage assembly moved radially along described rotating disk and the vertical sliding assembly vertically lifted.
By using technique scheme, radial slippage assembly can move the movement realizing pipet in radial directions diametrically, it is achieved its movement between pipettor and test tube, and vertical sliding assembly is capable of pipet and stretches into or remove test tube.
It is also preferred that the left described Zhuan Ye producer agency includes the substrate being rotationally connected with described draw-in groove inwall, on described substrate, revotating card is connected to film-making cylinder, is plugged with microscope slide between described film-making cylinder and described substrate.
By using technique scheme so that film-making cylinder can be arranged on substrate easily, and the cell in film-making cylinder can be laid immediately on microscope slide.
It is also preferred that the left described pedestal is provided with the grasping mechanism for capturing described film-making cylinder, described grasping mechanism includes translating assembly, lifting assembly and grabbing assembly.
By using technique scheme, it is possible to realize easily taking off film-making cylinder from substrate, first it is that translation assembly moves the top to film-making cylinder, then lifting assembly decline coordinates with film-making cylinder, and then, grabbing assembly captures film-making cylinder, lifting assembly lifting after having captured, then translation is return.
It is also preferred that the left described grabbing assembly includes capturing sleeve and being provided with the grippers for fastening with unclamp described film-making cylinder in the actuator driving described crawl sleeve to rotate, described crawl sleeve.
By using technique scheme, it is possible to conveniently coordinate with film-making cylinder, and realize capturing to it.
It is also preferred that the left described grippers is the annular air-pocket being arranged on described crawl sleeve lining.
By using technique scheme, it is possible to realize easily film-making cylinder being held tightly and unclamping, and, film-making cylinder will not be damaged by the flexibility of air bag.
It is also preferred that the left the outer rim of described pedestal is provided with annular fixing frame, described annular fixing frame is provided with some waste liquid cylinders.
By using technique scheme, it is possible to be easy to the collection of waste liquid, do not result in environmental pollution.
It is also preferred that the left be provided through the rotation slot of stator upper surface on the inwall of described draw-in groove, the side of described substrate is provided with the rotating shaft being rotationally connected with described rotation slot.
By using technique scheme, substrate can directly be set in draw-in groove from the top card of rotating disk, and it is easy for installation.
It is also preferred that the left described substrate is positioned at the quality that the quality of the one end inside rotating disk is positioned at one end of rotating disk outer rim more than described substrate.
By using technique scheme, it is not necessary to the auxiliary body additionally increasing other makes substrate be vertical state centrifugal rotation when, because after arrangement above, substrate can be automatically in vertical state under the distribution of sole mass.
It is also preferred that the left be provided with the fixed cover inserted for test tube in described first putting hole.
By using technique scheme, test tube can be fixed in fixed cover, and test tube is fixed more stable by fixed cover, so making centrifugal process more stable centrifugal when.
This utility model has an advantage that this utility model can realize moving liquid during realizing centrifugal and film-making by the cooperation of test tube, pipet and film-making cylinder on rotating disk, travel mechanism therein and grasping mechanism are capable of pipet and the crawl of film-making cylinder and movement, thus realize being centrifuged the automatization of film-making.
Accompanying drawing explanation
Fig. 1 is the top view of embodiment;
Fig. 2 is the side view of embodiment;
Fig. 3 is the axonometric drawing of embodiment;
Fig. 4 is the A portion enlarged diagram of Fig. 3;
Fig. 5 is the B portion enlarged diagram of Fig. 3;
Fig. 6 is the structural representation capturing sleeve in embodiment;
Fig. 7 is the partial structurtes schematic diagram of embodiment;
Fig. 8 is the partial exploded view of embodiment.
In figure: 1, rotating disk;11, stator;111, the first putting hole;1111, the first stopper slot;112, the second putting hole;12, draw-in groove;2, annular fixing frame;21, waste liquid cylinder;3, Zhuan Ye producer agency;31, substrate;311, rotating shaft;32, film-making cylinder;4, test tube;41, fixed cover;411, observation port;412, the first limited block;5, pipet;6, pedestal;7, travel mechanism;71, radial slippage assembly;72, vertical sliding assembly;8, grasping mechanism;81, translation assembly;82, lifting assembly;83, sleeve is captured;831, annular air-pocket;84, motor is driven;85, trachea.
Detailed description of the invention
The utility model is described in further detail below in conjunction with the accompanying drawings.
Embodiment: a kind of cell chip preparing machine, including pedestal 6, pedestal 6 is provided with rotating disk 1, and rotating disk 1 is driven it to rotate by motor.The periphery of rotating disk 1 is provided with some stators 11, some stator 11 circumferentially arrays, draw-in groove 12 is formed between adjacent stator 11, it is provided with Zhuan Ye producer agency 3 in draw-in groove 12, stator 11 is provided with the first putting hole 111 placed for test tube 4 and the second putting hole 112 placed for pipet 5.
Being provided with the fixed cover 41 inserted for test tube 4 in the first putting hole 111, this fixed cover 41 is consistent with the gabarit of test tube 4, and the internal diameter of fixed cover 41 is equal with the external diameter of test tube 4, and such test tube 4 will not rock in being placed on fixed cover 41.Wherein, fixed cover 41 and the first putting hole 111 grafting, and it is provided with the circumferential limit assembly that restriction fixed cover 41 circumferentially rotates between the two.This circumference limit assembly includes the first stopper slot 1111 being arranged on the first putting hole 111 inwall, first stopper slot 1111 is provided with two on the inwall of the first putting hole 111 and is symmetrical arranged, and the perisporium of fixed cover 41 is provided with and blocks, with the first stopper slot 1111, the first limited block 412 set.Further, fixed cover 41 is provided with the observation port 411 of the strip being vertically arranged.
Secondly, the outer rim of pedestal 6 is provided with annular fixing frame 2, and annular fixing frame 2 is provided with some waste liquid cylinders 21, and its circumference array is arranged on annular fixing frame 2.
In the present embodiment, Zhuan Ye producer agency 3 includes the substrate 31 being rotationally connected with draw-in groove 12 inwall, and on substrate 31, revotating card is connected to film-making cylinder 32, is plugged with microscope slide between film-making cylinder 32 and substrate 31.Being provided through the rotation slot of stator 11 upper surface on the inwall of draw-in groove 12, the side of substrate 31 is provided with the rotating shaft 311 being rotationally connected with rotation slot.Substrate 31 is positioned at the quality that the quality of the one end inside rotating disk 1 is positioned at one end of rotating disk 1 outer rim more than substrate 31.In the present embodiment, because basic inner side has more a fin than outside, so its quality is more than the quality in outside, owing to mass difference is little, so rotating disk 1 is static when, substrate 31 is still able to keep balance, but after rotating disk 1 rotates, substrate 31 is subject to centrifugal forces, and the inner side of substrate 31 naturally can be toward sagging, so that substrate 31 presents vertical state.Or, Zhuan Ye producer agency 3 can disclose as shown in a kind of Thinprep pap test pelletizer such as the Chinese patent of Application No. 201520522044.0.
First putting hole the 111, second putting hole 112 and waste liquid cylinder 21 being radially arranged along rotating disk 1, first putting hole 111 is arranged on same circumference with Zhuan Ye producer agency 3, travel mechanism 7 includes that the radial slippage assembly 71 moved radially along rotating disk 1 and the vertical sliding assembly 72 vertically lifted, radial slippage assembly 71 and vertical sliding assembly 72 all can be combined with cylinder by slide rail.It is additionally provided with on pedestal 6 and draws the travel mechanism 7 of liquid movement and for capturing the grasping mechanism 8 of film-making cylinder 32 for capturing pipet 5, grasping mechanism 8 includes translating assembly 81, lifting assembly 82 and grabbing assembly, and translation assembly 81 and lifting assembly 82 all can be combined with cylinder by slide rail.Grabbing assembly includes capturing sleeve 83 and capturing, for driving, the driving motor 84 that sleeve 83 rotates, the grippers for fastening with unclamp film-making cylinder 32 it is provided with in capturing sleeve 83, grippers is to be arranged on the annular air-pocket 831 captured on sleeve 83 inwall, annular air-pocket 831 is connected to air pump by trachea 85, controls it by electromagnetic valve and opens and closes.Film-making cylinder 32 is captured by needs when, first capture sleeve 83 and carry out sheathed with film-making cylinder 32, then airbag aeration, hold film-making cylinder 32 tightly, then driving motor 84 to rotate makes crawl sleeve 83 rotate and drive film-making cylinder 32 to rotate, so film-making cylinder 32 just can depart from substrate 31, and then lifting assembly 82 realizes capturing the rising of sleeve 83.
nullBeing centrifuged of this cell chip preparing machine is as follows with the process of film-making: first taken to test tube 4 by blood,It is centrifuged,After being centrifuged,Travel mechanism 7 moves to the top of test tube 4,Then decline and coordinate with pipet 5,Pipet 5 is blocked,Then go up,Move to the top of waste liquid cylinder 21 again,Then decline,Waste liquid is thrown in waste liquid cylinder 21,Then go up,Move to the top of test tube 4 again,Then decline and draw cell,Then go up,Rotating disk 1 rotates afterwards,Film-making cylinder 32 is made to be positioned at the lower section of pipet 5,Then pipet 5 declines under the effect of travel mechanism 7,Then cell is infused in film-making cylinder 32,Then go up and exit,Then rotating disk 1 rotates,Substrate 31 under the effect that rotating disk 1 rotates in being vertically arranged,Cell can be laid on microscope slide during rotating,So can complete the film-making of cell.After film-making completes, rotating disk 1 stops operating, then grasping mechanism 8 is moved horizontally to the top of film-making cylinder 32 and declines, first capturing sleeve 83 and carry out sheathed with film-making cylinder 32, then annular air-pocket 831 is inflated, and holds film-making cylinder 32 tightly, then driving motor 84 to rotate makes crawl sleeve 83 rotate and drive film-making cylinder 32 to rotate, so film-making cylinder 32 just can depart from substrate 31, and then lifting assembly 82 realizes capturing the rising of sleeve 83, completes to take cylinder.
The above is only preferred implementation of the present utility model, and protection domain of the present utility model is not limited merely to above-described embodiment, and all technical schemes belonged under this utility model thinking belong to protection domain of the present utility model.It should be pointed out that, for those skilled in the art, without departing from the some improvements and modifications under this utility model principle premise, these improvements and modifications also should be regarded as protection domain of the present utility model.

Claims (10)

1. a cell chip preparing machine, including pedestal, it is provided with rotating disk on described pedestal, the periphery of described rotating disk is provided with some stators, draw-in groove is formed between adjacent stator, Zhuan Ye producer agency it is provided with in described draw-in groove, it is characterised in that: it is provided with the first putting hole placed for test tube and the second putting hole placed for pipet on stator, described pedestal is additionally provided with the travel mechanism for capturing pipette, extract liquid movement.
Cell chip preparing machine the most according to claim 1, it is characterized in that: described first putting hole and described second putting hole being radially arranged along described rotating disk, described first putting hole and described Zhuan Ye producer agency are arranged on same circumference, and described travel mechanism includes the radial slippage assembly moved radially along described rotating disk and the vertical sliding assembly vertically lifted.
Cell chip preparing machine the most according to claim 1, it is characterised in that: described Zhuan Ye producer agency includes the substrate being rotationally connected with described draw-in groove inwall, and on described substrate, revotating card is connected to film-making cylinder, is plugged with microscope slide between described film-making cylinder and described substrate.
Cell chip preparing machine the most according to claim 3, it is characterised in that: described pedestal is provided with the grasping mechanism for capturing described film-making cylinder, and described grasping mechanism includes translating assembly, lifting assembly and grabbing assembly.
Cell chip preparing machine the most according to claim 4, it is characterised in that: described grabbing assembly includes capturing sleeve and being provided with the grippers for fastening with unclamp described film-making cylinder in the actuator driving described crawl sleeve to rotate, described crawl sleeve.
Cell chip preparing machine the most according to claim 5, it is characterised in that: described grippers is the annular air-pocket being arranged on described crawl sleeve lining.
Cell chip preparing machine the most according to claim 1, it is characterised in that: the outer rim of described pedestal is provided with annular fixing frame, and described annular fixing frame is provided with some waste liquid cylinders.
Cell chip preparing machine the most according to claim 3, it is characterised in that: being provided through the rotation slot of stator upper surface on the inwall of described draw-in groove, the side of described substrate is provided with the rotating shaft being rotationally connected with described rotation slot.
Cell chip preparing machine the most according to claim 8, it is characterised in that: described substrate is positioned at the quality that the quality of the one end inside rotating disk is positioned at one end of rotating disk outer rim more than described substrate.
Cell chip preparing machine the most according to claim 1, it is characterised in that: it is provided with the fixed cover inserted for test tube in described first putting hole.
CN201620007762.9U 2016-01-04 2016-01-04 Cell slide processing machine Active CN205449605U (en)

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Application Number Priority Date Filing Date Title
CN201620007762.9U CN205449605U (en) 2016-01-04 2016-01-04 Cell slide processing machine

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Application Number Priority Date Filing Date Title
CN201620007762.9U CN205449605U (en) 2016-01-04 2016-01-04 Cell slide processing machine

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108931414A (en) * 2017-05-23 2018-12-04 北京诚智光辉科技有限公司 Sectioning cells dye all-in-one machine
CN112284850A (en) * 2020-10-22 2021-01-29 四川大学华西医院 Intelligent analysis front-end processing equipment after gastroenterology biopsy
CN112881120A (en) * 2021-01-14 2021-06-01 杭州海世嘉生物科技有限公司 Auxiliary device for cell slide and centrifugation method

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108931414A (en) * 2017-05-23 2018-12-04 北京诚智光辉科技有限公司 Sectioning cells dye all-in-one machine
CN108931414B (en) * 2017-05-23 2020-09-18 北京诚智光辉科技有限公司 Cell film-making dyeing all-in-one
CN112284850A (en) * 2020-10-22 2021-01-29 四川大学华西医院 Intelligent analysis front-end processing equipment after gastroenterology biopsy
CN112881120A (en) * 2021-01-14 2021-06-01 杭州海世嘉生物科技有限公司 Auxiliary device for cell slide and centrifugation method
CN112881120B (en) * 2021-01-14 2024-01-26 杭州海世嘉生物科技有限公司 Auxiliary device for cell tabletting and centrifugation method

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