CN204758608U - Detection apparatus for former content of half quantitative determination blood sample median calcitonin of colloidal gold method - Google Patents

Detection apparatus for former content of half quantitative determination blood sample median calcitonin of colloidal gold method Download PDF

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Publication number
CN204758608U
CN204758608U CN201520395627.1U CN201520395627U CN204758608U CN 204758608 U CN204758608 U CN 204758608U CN 201520395627 U CN201520395627 U CN 201520395627U CN 204758608 U CN204758608 U CN 204758608U
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China
Prior art keywords
test strips
pad
container
clamping device
colloidal gold
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Expired - Fee Related
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CN201520395627.1U
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Chinese (zh)
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宋晓峰
余强华
陈铎
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BEIJING JINHUAKE BIOLOGICAL TECHNOLOGY Co Ltd
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BEIJING JINHUAKE BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The utility model provides a detection apparatus for former content of half quantitative determination blood sample median calcitonin of colloidal gold method, which comprises an outer shell, the test paper strip, test paper strip clamping device, the colorimetric card, disposable quantitative blood taking needle, blood dilutes the container, set up the transparent window on the shell, set up test paper strip clamping device and colorimetric card among the shell cavity under the transparent window, the test paper strip is fixed to test paper strip clamping device centre gripping, be provided with disposable quantitative blood taking needle in the shell recess, disposable quantitative blood taking needle passes through pipe connection blood and dilutes the container, blood dilutes the container and passes through pipe connection weak solution container, blood dilutes the container and connects a liquid pipe one end, it is located test paper strip top to go out the liquid pipe other end, the test paper strip includes that appearance pad, spraying colloidal gold labelled antibody and colloid carbon labelled antibody's combination pad, peridium has former monoclonal antibody of calcitonin and goat -anti rabbit polyclonal antibody's nitrocellulose membranes, the board that absorbs water, backup pad and ka sai, and the patient can own ration gather fingertip blood, contrast measuring.

Description

The pick-up unit of Procalcitonin content in colloidal gold method semiquantitative determination blood sample
Technical field
The utility model relates to a kind of pick-up unit, and particularly the pick-up unit of Procalcitonin content in colloidal gold method semiquantitative determination blood sample, belongs to medical equipment field.
Background technology
Procalcitonin (PCT) is to Systemic bacterial Infect And Diagnose and discriminating, the judgement of result for the treatment of and prognosis is than C reactive protein (CRP) and the various inflammatory reaction factor (bacterial endotoxin, TNF-α, IL-2) more responsive, have more value for clinical application.On market, existing PCT external diagnosis reagent is very many, comprise multiple quantitative detecting reagent and qualitative detection reagent, quantitative detecting reagent is in the majority with chemoluminescence method, euzymelinked immunosorbent assay (ELISA), these method complicated operations, and mostly be detection serum sample, therefore need the reviewer of specialty just can operate, be difficult to realize patient and test oneself.Qualitative detection reagent mostly is colloidal gold method, this method is easy and simple to handle, result can be judged by naked eyes, but because patient cannot self-precise acquisition finger tip blood or venous blood, and PCT content number directly affect the judgement of doctor and patient to conditions of patients, therefore this rough method is qualitatively only applicable to examination, and is not suitable for patient home and tests oneself or hospital examines soon, the PD situation of patient cannot being given, providing reference accurately the need of taking microbiotic.
Utility model content
The technical problems to be solved in the utility model is to overcome the deficiencies in the prior art, provides the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample, and patient oneself can be facilitated to detect.
For solving the problems of the technologies described above, the basic conception of the utility model employing technical scheme is:
A pick-up unit for Procalcitonin content in colloidal gold method semiquantitative determination blood sample, comprises shell, test strips, test strips clamping device, colorimetric card, disposable quantitative blood taking needle, hemodilution container.Shell is provided with transparency window, transparency window can folding, test strips clamping device and colorimetric card is respectively arranged with in shell inner cavity under transparency window, test strips gripping apparatus grips fixes test strips, test strips and colorimetric card are arranged side by side, test strips clamping device is connected to enclosure, case surface is provided with groove, disposable quantitative blood taking needle is provided with in groove, disposable quantitative blood taking needle is by tubes connection hemodilution container, hemodilution container is by tubes connection diluent container, hemodilution container connects eluate conduit one end, the eluate conduit other end is positioned at above test strips, test strips comprises loading pad, the pad of spraying colloidal gold labeled monoclonal antibody and colloidal-carbon labelled antibody, be coated with the nitrocellulose filter of Procalcitonin monoclonal antibody and goat-anti rabbit polyclonal antibody, water sucting plate, back up pad and jam, loading pad, pad, nitrocellulose filter, water sucting plate is all positioned in back up pad, loading pad, pad is positioned at nitrocellulose filter one end, part loading pad is overlapped on part pad, part pad is overlapped on nitrocellulose filter, water sucting plate is positioned at the nitrocellulose filter other end and part is overlapped on nitrocellulose filter, nitrocellulose filter is provided with detection line and nature controlling line, arrange and outward extending jam in back up pad both sides, jam and the clamping of test strips clamping device.
Further, test strips clamping device comprises base plate and symmetrically arranged two trough rims on base plate, place test strips in the semi-open groove that the base plate of two trough rims and test strips clamping device is formed, the jam that two trough rims are provided with gap and test strips is connected.
Further, transparency window one end is connected by axle with shell.
Further, the conduit between hemodilution container and diluent container is provided with valve, eluate conduit is provided with valve, hemodilution container connects syringe.
Further, each vitta of colorimetric card is all located at same plane.
The pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination of the utility model blood sample, be configured with disposable quantitative blood taking needle, patient can oneself quantitative collection finger tip blood, quantitative blood taking needle is furnished with quantitative whole blood dilution, directly oneself can complete collection and the dilution of sample in the family, other equipment is not needed to assist, after Sample Dilution is complete, drip appropriate sample in test strips, wait for three minutes just observable testing result, according to the quality-control product testing result of variable concentrations, correspondence is provided with the colorimetric card of Product checking result, it is 0.2ng/ml that this colorimetric card accurately gives PCT concentration when using this detection paper respectively, 0.5ng/ml, 2ng/ml, the colour band color of nature controlling line and detection line during 10ng/ml, thus provide PCT and be less than 0.2ng/ml, 0.2ng/ml ~ 0.5ng/ml, 0.5ng/ml ~ 2ng/ml, 2ng/ml ~ 10ng/ml, be greater than the situation of 10ng/ml five concentration ranges, therefore patient can detect by oneself the contents level learning Procalcitonin in health blood sample, thus to the medication of patient to select to provide guidance.And test strips and colorimetric card are all arranged in the enclosure, and observed by transparency window, prevent pollution.The transparency window that shell is arranged can folding, thus can take out the test strips clamping device of support test strips and then change test strips, and the jam in test strips can prevent test strips from dropping.The utility model can detect whole blood, serum or plasma sample, and patient oneself can be realized can detect in the family, by detection line and the supporting colorimetric card of product are contrasted and can carry out sxemiquantitative judgement to the PCT content in sample, the concentration ranges that sxemiquantitative judges, between 0.2ng/ml ~ 10ng/ml, can meet the needs that family tests oneself.
Accompanying drawing explanation
Fig. 1 is the structural representation of the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination of the utility model blood sample;
Fig. 2 is the structural representation of test strips.
Fig. 3 is the reference significance table of PCT content in blood.
1, shell 2, transparency window 3, test strips 4, colorimetric card 5, quantitatively blood taking needle 31, loading pad 32, pad 33, nitrocellulose filter 34, water sucting plate 35, back up pad 36, jam.
Embodiment
As shown in Figure 1, the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample, comprises shell, test strips, test strips clamping device, colorimetric card, disposable quantitative blood taking needle, hemodilution container.
Shell is provided with transparency window, transparency window can folding, transparency window one end is connected by axle with shell, test strips clamping device and colorimetric card is respectively arranged with in shell inner cavity under transparency window, test strips gripping apparatus grips fixes test strips, test strips and colorimetric card are arranged side by side, and test strips clamping device is connected to enclosure.Each vitta of colorimetric card is all located at same plane.
Case surface is provided with groove, disposable quantitative blood taking needle is provided with in groove, disposable quantitative blood taking needle is by tubes connection hemodilution container, hemodilution container is by tubes connection diluent container, hemodilution container connects eluate conduit one end, and the eluate conduit other end is positioned at above test strips.Conduit between hemodilution container and diluent container is provided with valve, eluate conduit is provided with valve, hemodilution container connects syringe.
Test strips comprises loading pad, spraying colloidal gold labeled monoclonal antibody and the pad of colloidal-carbon labelled antibody, the nitrocellulose filter being coated with Procalcitonin monoclonal antibody and goat-anti rabbit polyclonal antibody, water sucting plate, back up pad and jam,
Loading pad, pad, nitrocellulose filter, water sucting plate are all positioned in back up pad, loading pad, pad are positioned at nitrocellulose filter one end, part loading pad is overlapped on part pad, part pad is overlapped on nitrocellulose filter, water sucting plate is positioned at the nitrocellulose filter other end and part is overlapped on nitrocellulose filter, nitrocellulose filter is provided with detection line and nature controlling line, arranges and outward extending jam, jam and the clamping of test strips clamping device in back up pad both sides.
Test strips clamping device comprises base plate and symmetrically arranged two trough rims on base plate, and place test strips in the semi-open groove that the base plate of two trough rims and test strips clamping device is formed, the jam that two trough rims are provided with gap and test strips is connected.
Can prevent colorimetric card from losing in the enclosure due to colorimetric card or pollute.
As shown in Figure 2, test strips comprises loading pad, the nitrocellulose filter of spraying colloidal gold labeled monoclonal antibody and the pad of colloidal-carbon labelled antibody, Procalcitonin monoclonal antibody and goat-anti rabbit polyclonal antibody, water sucting plate, back up pad and jam.
Loading pad, pad, nitrocellulose filter, water sucting plate are all positioned in back up pad, loading pad, pad are positioned at nitrocellulose filter one end, part loading pad is overlapped on part pad, part pad is overlapped on nitrocellulose filter, water sucting plate is positioned at the nitrocellulose filter other end and part is overlapped on nitrocellulose filter, nitrocellulose filter is provided with detection line and nature controlling line, arranges in back up pad bottom and jam, jam and the clamping of test strips clamping device to downward-extension.
Case surface is provided with groove, disposable quantitative blood taking needle is provided with in groove, disposable quantitative blood taking needle is by tubes connection hemodilution container, hemodilution container is by tubes connection diluent container, hemodilution container connects eluate conduit one end, and the eluate conduit other end is positioned at above test strips.Conduit between hemodilution container and diluent container is provided with valve, eluate conduit is provided with valve, hemodilution container connects syringe.During blood sampling, extract quantitative blood by being delivered to hemodilution container, quantitative dilution is extracted to hemodilution container again by syringe, after hemodilution is completed, close the supravasal valve between hemodilution container and diluent container, open the valve on eluate conduit, the blood utilizing syringe to push dilute in right amount to the loading pad of test strips, and carries out contrast detection according to the detection line that nitrocellulose filter is arranged and nature controlling line and colorimetric card.
And carry out self-inspection reference according to the data in Fig. 3.
The pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination of the utility model blood sample, be configured with disposable quantitative blood taking needle, patient can oneself quantitative collection finger tip blood, quantitative blood taking needle is furnished with quantitative whole blood dilution, directly oneself can complete collection and the dilution of sample in the family, other equipment is not needed to assist, after Sample Dilution is complete, drip appropriate sample in test strips, wait for three minutes just observable testing result, according to the quality-control product testing result of variable concentrations, correspondence is provided with the colorimetric card of Product checking result, it is 0.2ng/ml that this colorimetric card accurately gives PCT concentration when using this detection paper respectively, 0.5ng/ml, 2ng/ml, the colour band color of nature controlling line and detection line during 10ng/ml, thus provide PCT and be less than 0.2ng/ml, 0.2ng/ml ~ 0.5ng/ml, 0.5ng/ml ~ 2ng/ml, 2ng/ml ~ 10ng/ml, be greater than the situation of 10ng/ml five concentration ranges, therefore patient can detect by oneself the contents level learning Procalcitonin in health blood sample, thus to the medication of patient to select to provide guidance.And test strips and colorimetric card are all arranged in the enclosure, and observed by transparency window, prevent pollution.The transparency window that shell is arranged can folding, thus can take out the test strips clamping device of support test strips and then change test strips, and the jam in test strips can prevent test strips from dropping.The utility model can detect whole blood, serum or plasma sample, and patient oneself can be realized can detect in the family, by detection line and the supporting colorimetric card of product are contrasted and can carry out sxemiquantitative judgement to the PCT content in sample, the concentration ranges that sxemiquantitative judges, between 0.2ng/ml ~ 10ng/ml, can meet the needs that family tests oneself.
Embodiment in above-described embodiment can combine further or replace; and embodiment is only be described preferred embodiment of the present utility model; not design of the present utility model and scope are limited; under the prerequisite not departing from the utility model design philosophy; the various changes and modifications that in this area, professional and technical personnel makes the technical solution of the utility model, all belong to protection domain of the present utility model.

Claims (5)

1. the pick-up unit of Procalcitonin content in colloidal gold method semiquantitative determination blood sample, is characterized in that: comprise shell, test strips, test strips clamping device, colorimetric card, disposable quantitative blood taking needle, hemodilution container,
Shell is provided with transparency window, and transparency window can folding, is respectively arranged with test strips clamping device and colorimetric card in the shell inner cavity under transparency window, test strips gripping apparatus grips fixes test strips, test strips and colorimetric card are arranged side by side, and test strips clamping device is connected to enclosure
Case surface is provided with groove, disposable quantitative blood taking needle is provided with in groove, disposable quantitative blood taking needle is by tubes connection hemodilution container, hemodilution container is by tubes connection diluent container, hemodilution container connects eluate conduit one end, and the eluate conduit other end is positioned at above test strips;
Test strips comprises loading pad, spraying colloidal gold labeled monoclonal antibody and the pad of colloidal-carbon labelled antibody, the nitrocellulose filter being coated with Procalcitonin monoclonal antibody and goat-anti rabbit polyclonal antibody, water sucting plate, back up pad and jam,
Loading pad, pad, nitrocellulose filter, water sucting plate are all positioned in back up pad, loading pad, pad are positioned at nitrocellulose filter one end, part loading pad is overlapped on part pad, part pad is overlapped on nitrocellulose filter, water sucting plate is positioned at the nitrocellulose filter other end and part is overlapped on nitrocellulose filter, nitrocellulose filter is provided with detection line and nature controlling line, arranges and outward extending jam, jam and the clamping of test strips clamping device in back up pad both sides.
2. the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample according to claim 1, it is characterized in that: test strips clamping device comprises base plate and symmetrically arranged two trough rims on base plate, place test strips in the semi-open groove that the base plate of two trough rims and test strips clamping device is formed, the jam that two trough rims are provided with gap and test strips is connected.
3. the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample according to claim 1, is characterized in that: transparency window one end is connected by axle with shell.
4. the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample according to claim 1, it is characterized in that: the conduit between hemodilution container and diluent container is provided with valve, eluate conduit is provided with valve, and hemodilution container connects syringe.
5. the pick-up unit of Procalcitonin content in a kind of colloidal gold method semiquantitative determination blood sample according to claim 1, is characterized in that: each vitta of colorimetric card is all located at same plane.
CN201520395627.1U 2015-06-10 2015-06-10 Detection apparatus for former content of half quantitative determination blood sample median calcitonin of colloidal gold method Expired - Fee Related CN204758608U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105954507A (en) * 2016-04-26 2016-09-21 北京言必信科技有限公司 ELISA kit
CN106053796A (en) * 2016-07-15 2016-10-26 陶少强 Detecting system and detecting method for PCT chromatography
CN106370851A (en) * 2016-12-03 2017-02-01 百奥森(江苏)食品安全科技有限公司 Quick ketamine test device for porcine pseudorabies antibody
CN106525837A (en) * 2016-12-07 2017-03-22 无锡艾科瑞思产品设计与研究有限公司 Natamycin determination method and natamycin determination card
CN106680478A (en) * 2017-02-24 2017-05-17 成都微瑞生物科技有限公司 Gold labeled detection system and method based on cloud platform
CN107860908A (en) * 2017-11-07 2018-03-30 兰赫(上海)生物科技有限公司 Biochemical detection kit for detection and analysis
CN109100505A (en) * 2018-08-22 2018-12-28 宁波奥丞生物科技有限公司 A kind of immunofluorescent reagent box of quantitative detection blood vessel endothelium marker CD105
CN111380724A (en) * 2020-04-24 2020-07-07 万华普曼生物工程有限公司 Body fluid sample collecting and inspecting device

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105954507A (en) * 2016-04-26 2016-09-21 北京言必信科技有限公司 ELISA kit
CN106053796A (en) * 2016-07-15 2016-10-26 陶少强 Detecting system and detecting method for PCT chromatography
CN106053796B (en) * 2016-07-15 2017-09-29 陶少强 A kind of detecting system and detection method chromatographed for PCT
CN106370851A (en) * 2016-12-03 2017-02-01 百奥森(江苏)食品安全科技有限公司 Quick ketamine test device for porcine pseudorabies antibody
CN106525837A (en) * 2016-12-07 2017-03-22 无锡艾科瑞思产品设计与研究有限公司 Natamycin determination method and natamycin determination card
CN106680478A (en) * 2017-02-24 2017-05-17 成都微瑞生物科技有限公司 Gold labeled detection system and method based on cloud platform
CN107860908A (en) * 2017-11-07 2018-03-30 兰赫(上海)生物科技有限公司 Biochemical detection kit for detection and analysis
CN109100505A (en) * 2018-08-22 2018-12-28 宁波奥丞生物科技有限公司 A kind of immunofluorescent reagent box of quantitative detection blood vessel endothelium marker CD105
CN111380724A (en) * 2020-04-24 2020-07-07 万华普曼生物工程有限公司 Body fluid sample collecting and inspecting device
CN111380724B (en) * 2020-04-24 2023-08-25 万华普曼生物工程有限公司 Body fluid sample sampling and detecting device

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Granted publication date: 20151111