CN203365311U - Spectral domain OCT (optical coherence tomography) full-scale imaging system based on mobile optical grating and spacial carrier frequency - Google Patents
Spectral domain OCT (optical coherence tomography) full-scale imaging system based on mobile optical grating and spacial carrier frequency Download PDFInfo
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Abstract
The utility model discloses a spectral domain OCT full-scale imaging system based on a mobile optical grating and spacial carrier frequency, which adopts the mobile optical grating to replace a reference reflecting mirror in traditional spectral domain OCT and introduces the spacial carrier frequency which doesn't require optical path modulation in the transverse scanning direction. Fourier transform is firstly performed on an interference spectrum signal obtained by detection in the transverse scanning direction, then, band-pass filtering with the spacial carrier frequency amount as a center is applied, inverse Fourier transform is performed on a filtering signal, and finally, Fourier transform is performed on the signal in the axial direction to obtain a full-scale OCT image after a mirror image of a sample is eliminated. According to the spectral domain OCT full-scale imaging system based on the mobile optical grating and spacial carrier frequency, the full-scale spectral domain OCT imaging can be obtained on the premise that any additional optical path difference is not introduced, and the sensitivity reduction caused by the optical path difference accumulated in a traditional spacial carrier frequency system is prevented.
Description
Technical field
The utility model relates to optical coherent chromatographic imaging (OCT) technology, relates in particular to a kind of movement-based grating space carrier frequency spectral coverage OCT gamut imaging system.
Background technology
Optical coherent chromatographic imaging (Optical Coherence Tomography, OCT) is a kind of non-intruding, non-contacting imaging technique, as a kind of brand-new, develop imaging technique rapidly, there is the series of advantages such as high-resolution, harmless, real time imagery.And spectral coverage OCT (Spectral domain OCT, SD-OCT) system than first generation OCT technology (Time domain OCT, TD-OCT), has clear superiority at aspects such as image taking speed, signal to noise ratio (S/N ratio) and sensitivity as second generation OCT technology.The greatest problem that at present the SD-OCT system exists is the mirror image that the complex conjugate item that produced by the real function Fourier transform causes.In actual applications, for fear of obscuring of mirror image and real image, generally testing sample is placed on to a side of zero optical path difference position, and near the highest zone of sensitivity often zero light path, therefore eliminate mirror image, imaging depth is doubled, realize the gamut imaging, always be the focus of SD-OCT research.
People have proposed the whole bag of tricks and have built the interference spectrum signal of plural form to eliminate the conjugation item.The method that obtains the earliest multiple interference spectrum signal is based on phase shift interference art (Phase Shifting Interferometry, PSI) theory.M.Wojtkowski, based on the PSI method, realizes five step transposition in the SD-OCT system, by amplitude and the phase information that calculates interference spectrum, thereby obtains multiple interference spectrum.And eliminate the most frequently used method of complex conjugate mirror image in current SD-OCT system, it is the linear B-M method proposed by Y.Yasuno.Linear B-M method can be thought the expansion of traditional transposition method, has more efficient data processing speed, can suppress the noise caused by dispersion transposition error simultaneously.But introduced transposition amount pi/2 between adjacent A-scan in linear B-M method, if the transversal scanning scope will add up more greatly a larger optical path difference.Because the sensitivity of the SD-OCT system increase along with imaging depth reduces, thus optical path difference of this accumulative total can cause last image transversely the direction of scanning signal to noise ratio (S/N ratio) descend.
Summary of the invention
The utility model, for the deficiencies in the prior art, has proposed a kind of movement-based grating space carrier frequency spectral coverage OCT gamut imaging system.
The purpose of this utility model is achieved by the following technical solution: the spectral coverage OCT gamut imaging system of movement-based grating space carrier frequency mainly comprises wideband light source, the 2x2 broadband optical fiber coupler, the 1x2 broadband optical fiber coupler, sample arm, reference arm, feeler arm; Sample arm comprises the first collimation lens, X-Y scanning galvanometer, the first convergent lens, sample; Reference arm comprises the second collimation lens, the first grating, the second convergent lens, the 3rd convergent lens, the second grating, the 3rd collimation lens, stepper motor; Feeler arm comprises the 4th collimation lens, the 3rd grating, the 4th convergent lens, high speed linear array CCD;
Described wideband light source is connected with an input end of 2x2 broadband optical fiber coupler, an output terminal of 2x2 broadband optical fiber coupler is connected with the first collimation lens, the X-Y scanning galvanometer is positioned on the emitting light path of the first collimation lens, the first convergent lens is positioned on the reflected light path of X-Y scanning galvanometer, the X-Y scanning galvanometer is positioned at the front focal plane of the first convergent lens, and sample is positioned at the back focal plane of the first convergent lens; Another output terminal of 2x2 broadband optical fiber coupler is connected with the second collimation lens; The first grating is fixed on stepper motor, be arranged in the emitting light path of the second collimation lens, the second convergent lens is positioned on the reflected light path of the first grating, the 3rd convergent lens is positioned at the emitting light path of the second convergent lens, the back focal plane of the front focal plane of the 3rd convergent lens and the second convergent lens overlaps, the second grating is positioned on the emitting light path of the 3rd convergent lens, and the 3rd collimation lens is positioned on the reflected light path of the second grating; Input end of 1x2 broadband optical fiber coupler and another input end of 2x2 broadband optical fiber coupler are connected, another input end of 1x2 broadband optical fiber coupler is connected with the 3rd collimation lens, and the output terminal of 1x2 broadband optical fiber coupler is connected with the 4th collimation lens; The 3rd grating is positioned on the emitting light path of the 4th collimation lens, and the 4th convergent lens is positioned on the emitting light path of the 3rd grating, and high speed linear array CCD is positioned on the back focal plane of the 4th convergent lens.
With background technology, compare, the beneficial effect the utlity model has is:
1, than general OCT system, the utility model can replace along the grating of grating face translation the level crossing in the reference arm with one, can introduce very easily the required phase velocity of the mirror image that disappears postpones, process and just can obtain the gamut OCT image without mirror image by simple filtering, imaging depth is doubled;
2,, than general linear B-M method, the utility model disappears when the required phase velocity of mirror image postpones in introducing, does not introduce any group velocity delay.In linear B-M method, introduced transposition amount pi/2 between adjacent A-Scan, if the transversal scanning scope will add up more greatly a larger optical path difference.Because the sensitivity of spectral coverage OCT (SD-OCT) the system increase along with imaging depth reduces, thus optical path difference of this accumulative total can cause last image transversely the direction of scanning signal to noise ratio (S/N ratio) descend.This method, when eliminating mirror image, can not cause because of the relation of sensitivity signal to noise ratio (S/N ratio) to descend, so image quality can not descend.
The accompanying drawing explanation
Fig. 1 is spectral domain optical coherence tomography system schematic diagram of the present utility model;
Fig. 2 is the spatial spectral distribution figure in data handling procedure described in the utility model;
Fig. 3 is reference arm part principle schematic in the utility model.
In figure: 1, wideband light source, 2, the 2x2 broadband optical fiber coupler, 3, collimation lens, 4, the X-Y scanning galvanometer, 5, convergent lens, 6, sample, 7, collimation lens, 8, grating, 9, convergent lens, 10, convergent lens, 11, grating, 12, collimation lens, 13,1x2 broadband optical fiber coupler, 14, collimation lens, 15, grating, 16, convergent lens, 17, high speed linear array CCD, 18, sample arm, 19, reference arm, 20, feeler arm, 21, stepper motor.
Specific embodiments
As shown in Figure 1, the utility model mainly comprises wideband light source 1,2x2 broadband optical fiber coupler 2,1x2 broadband optical fiber coupler 13, sample arm 18, reference arm 19, feeler arm 20.Sample arm comprises the first collimation lens 3, X-Y scanning galvanometer 4, the first convergent lenses 5, sample 6; Reference arm comprises the second collimation lens 7, the first grating 8, the second convergent lens 9, the three convergent lens 10, the second grating 11, the three collimation lenses 12, stepper motor 21; Feeler arm comprises the 4th collimation lens 14, the three grating 15, the four convergent lenses 16, high speed linear array CCD 17.
Wideband light source 1 is connected with an input end of 2x2 broadband optical fiber coupler 2, an output terminal of 2x2 broadband optical fiber coupler is connected with the first collimation lens 3, X-Y scanning galvanometer 4 is positioned on the emitting light path of the first collimation lens 3, the first convergent lens 5 is positioned on the reflected light path of X-Y scanning galvanometer 4, X-Y scanning galvanometer 4 is positioned at the front focal plane of the first convergent lens 5, and sample 6 is positioned at the back focal plane of the first convergent lens 5; Another output terminal of 2x2 broadband optical fiber coupler is connected with the second collimation lens 7; The first grating 8 is fixed on stepper motor 21, be arranged in the emitting light path of the second collimation lens 7, the second convergent lens 9 is positioned on the reflected light path of the first grating 8, the 3rd convergent lens 10 is positioned at the emitting light path of the second convergent lens 9, the back focal plane of the front focal plane of the 3rd convergent lens 10 and the second convergent lens 9 overlaps, the second grating 11 is positioned on the emitting light path of the 3rd convergent lens 10, and the 3rd collimation lens 12 is positioned on the reflected light path of the second grating; Input end of 1x2 broadband optical fiber coupler 13 and another input end of 2x2 broadband optical fiber coupler 2 are connected, another input end of 1x2 broadband optical fiber coupler 13 is connected with the 3rd collimation lens 12, and the output terminal of 1x2 broadband optical fiber coupler 13 is connected with the 4th collimation lens 14.The 3rd grating 15 is positioned on the emitting light path of the 4th collimation lens 14, and the 4th convergent lens 16 is positioned on the emitting light path of the 3rd grating 15, and high speed linear array CCD 17 is positioned on the back focal plane of the 4th convergent lens 16.
The low-coherent light out from wideband light source 1, incide 2x2 broadband optical fiber coupler 2, after light splitting, one tunnel enters sample arm 18, through the first collimation lens 3, after X-Y scanning galvanometer 4, the first convergent lenses 5, be radiated on sample 6, the flashlight Yan Yuan road be reflected back through sample 6 is returned, through 2x2 broadband optical fiber coupler 2 to 1x2 broadband optical fiber coupler 13 places;
As shown in Figure 3, enter reference arm 19 from the another light beam of 2x2 broadband optical fiber coupler 2 outgoing, through the second collimation lens 7, be radiated on the first grating 8, the first grating 8 is fixed on stepper motor 21, stepper motor 21 is controlled by computer, with certain speed v, along the translation of grating face, introduces modulated carriers f
m, reference light is radiated on the second grating 11 after the first grating 8 light splitting are by the second convergent lens 9, the three convergent lenses 10, and diffraction light again is converged to again directional light and is entered the second collimation lens 12, then to 1x2 broadband optical fiber coupler 13 places;
Sample light and reference light meet at 1x2 broadband optical fiber coupler 13 places, and interfere, and interference light enters feeler arm 20, after the 4th collimation lens 14, are radiated on the 3rd grating 15.After grating beam splitting, the coloured light of different wave length focuses on the diverse location on high speed linear array CCD 17 through the 4th convergent lens 16, and 17 pairs of interference spectrums of high speed linear array CCD are gathered, and the spectral signal of collection finally imports computing machine into.To the advanced laterally Fourier transform of the interference spectrum collected, obtain space distribution as shown in Figure 2, because introduce modulated carriers f in computing machine
mcause, the spatial frequency spectrum of complex conjugate item and real image is separated, leach the real image part on the right by the filtering of windowing, then carry out inverse Fourier transform, just obtained the interference spectrum signal of plural form, this signal is carried out to Fourier transform more vertically, the sample structure pattern after the mirror image that just obtained disappearing.
Claims (1)
1. the spectral coverage OCT gamut imaging system of movement-based grating space carrier frequency, mainly comprise wideband light source, 2x2 broadband optical fiber coupler, 1x2 broadband optical fiber coupler, sample arm, reference arm, feeler arm; Sample arm comprises the first collimation lens, X-Y scanning galvanometer, the first convergent lens, sample; Reference arm comprises the second collimation lens, the first grating, the second convergent lens, the 3rd convergent lens, the second grating, the 3rd collimation lens, stepper motor; Feeler arm comprises the 4th collimation lens, the 3rd grating, the 4th convergent lens, high speed linear array CCD;
It is characterized in that: wideband light source is connected with an input end of 2x2 broadband optical fiber coupler, an output terminal of 2x2 broadband optical fiber coupler is connected with the first collimation lens, the X-Y scanning galvanometer is positioned on the emitting light path of the first collimation lens, the first convergent lens is positioned on the reflected light path of X-Y scanning galvanometer, the X-Y scanning galvanometer is positioned at the front focal plane of the first convergent lens, and sample is positioned at the back focal plane of the first convergent lens; Another output terminal of 2x2 broadband optical fiber coupler is connected with the second collimation lens; The first grating is fixed on stepper motor, be arranged in the emitting light path of the second collimation lens, the second convergent lens is positioned on the reflected light path of the first grating, the 3rd convergent lens is positioned at the emitting light path of the second convergent lens, the back focal plane of the front focal plane of the 3rd convergent lens and the second convergent lens overlaps, the second grating is positioned on the emitting light path of the 3rd convergent lens, and the 3rd collimation lens is positioned on the reflected light path of the second grating; Input end of 1x2 broadband optical fiber coupler and another input end of 2x2 broadband optical fiber coupler are connected, another input end of 1x2 broadband optical fiber coupler is connected with the 3rd collimation lens, and the output terminal of 1x2 broadband optical fiber coupler is connected with the 4th collimation lens; The 3rd grating is positioned on the emitting light path of the 4th collimation lens, and the 4th convergent lens is positioned on the emitting light path of the 3rd grating, and high speed linear array CCD is positioned on the back focal plane of the 4th convergent lens.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103267732A (en) * | 2013-05-21 | 2013-08-28 | 浙江大学 | Full-range imaging method and system based on mobile optical grating spatial carrier frequency spectral domain OCT (optical coherence tomography) |
| CN105852816A (en) * | 2016-05-16 | 2016-08-17 | 浙江大学 | Angle composite speckle denoising method and system for full-channel modulation encoding |
| CN107644798A (en) * | 2016-07-20 | 2018-01-30 | 中国科学院高能物理研究所 | Telescope imaging system and method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103267732A (en) * | 2013-05-21 | 2013-08-28 | 浙江大学 | Full-range imaging method and system based on mobile optical grating spatial carrier frequency spectral domain OCT (optical coherence tomography) |
| CN105852816A (en) * | 2016-05-16 | 2016-08-17 | 浙江大学 | Angle composite speckle denoising method and system for full-channel modulation encoding |
| CN107644798A (en) * | 2016-07-20 | 2018-01-30 | 中国科学院高能物理研究所 | Telescope imaging system and method |
| CN107644798B (en) * | 2016-07-20 | 2019-08-06 | 中国科学院高能物理研究所 | Telescope imaging system and method |
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