CN203154602U - Skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field - Google Patents
Skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field Download PDFInfo
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- CN203154602U CN203154602U CN 201320089161 CN201320089161U CN203154602U CN 203154602 U CN203154602 U CN 203154602U CN 201320089161 CN201320089161 CN 201320089161 CN 201320089161 U CN201320089161 U CN 201320089161U CN 203154602 U CN203154602 U CN 203154602U
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Abstract
A skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field comprises an ultrasonic transducer, an electrode plate, a laser diode, a medicine storage utensil patch, a gel sheet and a plastic shell for fixing the patch, wherein the ultrasonic transducer and the electrode plate are integrated into one body by an insulation adhesive and respectively used for outputting the ultrasonic mechanical energy and the electric field energy, four laser diodes are arranged on the periphery of the electrode plate to output the laser energy, patch fixation lug grooves in an interval of 90 degrees are arranged on the plastic shell and used for fixing the medicine storage utensil patch, the medicine storage utensil patch is an aluminum round concave object and provided with the gel sheet of the treatment medicine inside, and contacted with human body. The skin positioning transdermal delivery device is connected with a treatment instrument with functions of ultrasonic wave, electric field, electroporation and laser, and then the ultrasonic wave, electric field, electroporation and laser radiation ways are employed, thus the medicine is delivered to the part of the human body in need of treatment in the transdermal way. The geometric shape and dimension of the device are designed according to the case design, so as to conform to the principles of the human body engineering, thus the contact feeling of the device with human body is comfortable, the device is convenient and simple to use and maintain.
Description
Technical field
This utility model relates to a kind of acousto-optic electricity and helps skin location transdermal device.Needs can be injected the medicine of human body, utilize physical action processes such as ultrasound wave, electric field and laser irradiation, not have under traditional intramuscular injection situation, penetrate the position of achieving the goal effectively through skin.This utility model belongs to bioscience, general physics and electronic technology field.
Background technology
For a long time, in medical procedure, generally be external application or take medicine orally and injection injection to the method for patient's administration.Carry drug effect for needs by blood and reach the purpose of curing the disease, pill is swallowed and injection injection is a kind of effective method, and biological agent processes such as the blood circulation by human body, digestive system are brought drug effect into human body.But needs are given the topical of human body, as hyperosteogeny, myalgia etc., traditional administering mode is to paste or smearing ointment, namely stick plaster at the corresponding position of patient, allow medicine arrive the position that needs treatment through human body skin (percutaneous) naturally osmotic, the time efficient long, transdermal that medicine reaches the tissue position is not high.If introduce some physical actions, strengthen the effect of percutaneous dosing, will be very significant, can improve service efficiency, the raising therapeutic efficiency of medicine, alleviate the misery of sufferer.
Utilize physical actions such as ultrasound wave, electric field to realize the treatment existing research at home and abroad of percutaneous dosing, studied treatment problem (the Vesna. Zderic of the ultrasound wave administration of 20KHz as that people such as grade of Vincent, Shahram Vaezy, Roy W, et al.Ocular drug delivery using 20 KHz ultrasound[J]. Ultrasound in Medicine; Biology, 2002,28 (6): 823); The application of the ultrasound wave transdermal of the Zhou Wansong of General Hospital of Beijing Military Command is studied.(medicine penetrates the Clinical advances of therapy, the 1st phase of " applied acoustics " calendar year 2001, people such as the Chen Fang of Shanghai Institute of Pharmaceutical Industry have studied research (electroporation technology application in transdermal administration, the Chinese Journal of Pharmaceuticals of electroporation in clinical practice, 2004,35).
Along with the transdermal Study on Technology, utilize the medical product of these technology in China clinical practice to be arranged also, as the development and production of Henan three unrestrained medical Technew SA ultrasonic pulse electric conductance therapeutic instrument, this instrument mainly passes through ultrasound wave, medicine is entered in the body and performance is local and the whole body therapeutic effect through complete skin, functions such as disturbing electric and low frequency electricity has superposeed again simultaneously.Nanchang New Long March medical science and technology Development Co., Ltd has produced a kind of ultrasonic conductivity meter, this instrument can pass through high-end physical means such as electroporation, ultrasonic cavitation, between skin, tissue and cell, form specific artificial bio-membrane's passage, pass through the brute force driving effect of functions such as ultrasound wave convection current running, radiation pressure again, make medicine directly enter organ and the tissue of pathological changes along artificial bio-membrane's passage, and form high concentration in the part rapidly and soak into the district, promote that medicine turns round in cell, directly bring into play the therapeutical effect of medicine.Also there is Crinis Carbonisatus to understand relevant patent, Guo Yan Xiang patent of invention " a kind of ultrasound wave medicinal liquid permeameter " as the ShenYang, Liaoning Province city, the patent No.: 90103647, the Weng Chunxiao in Henan Province, Hu Yamei, Zheng Shuli etc. have invented a kind for the treatment of head of ultrasonic electric conductance transdermal delivery device, can be by ultrasound wave through the skin transdermal (patent No.: 00241525).
The device of a key is the treatment probe in above equipment and the technology, just converts electric energy to corresponding energy, medicine is sent to the equipment of human body.In conventional device, come with some shortcomings, the one, the effect physical quantity of probe is single, and the employing ultrasound wave that has or ultrasound wave and electric field combination do not have the laser miscellaneous function; The 2nd, there is defective in the sonde configuration design, and coupling in use is not strong, is easy to generate deformation; The 3rd, when contacting with human body owing to off size reason, the phenomenon that comes off often appears.More than these deficiencies, greatly reduce the administering effect of probe.
The utility model content
This utility model is intended to overcome the deficiency of existing treatment probe, provides a kind of acousto-optic electricity to help skin location transdermal device.This device can use principle of human engineering and acoustics, optical theory with ultrasound wave, electroporation, electric field and four kinds of administering mode Combination application of laser, medicament is effectively permeated give the human body that needs treatment; Treatment probe (being the medicament paster) can be fixed and reduce the paster distortion, has overcome probe and has contacted bad, electrode easy deformation, medicament and the not strong shortcoming of body-coupled, convenient and reliable operation, transdermal efficient height with human body.
The technical scheme that its technical problem that solves this utility model adopts is:
A kind of acousto-optic electricity helps skin location transdermal device, and this device comprises: electrode slice, rubber washer, cabinet, laser circuit plate, drug storage ware paster, insulation rubberizing, ultrasonic transducer, laser diode; Electrode slice is bonding by insulation viscose glue and ultrasonic transducer, place the cabinet the inside, the one side of described electrode slice is fixed by the shell edge, edge at another side is placed with rubber washer, the circular laser circuit plate that 4 laser diodes are installed be pressed in rubber washer above, guarantee get along well circular laser circuit plate contact and be in free movement state of ultrasonic transducer, the position of 4 laser diodes be dispersed in electrode slice around, drug storage ware paster is fixed on the electrode slice and the electrode slice surface keeps excellent contact, and does not cover the laser diode light beam; The electric wire of described electrode slice, ultrasonic transducer and laser diode is drawn with therapeutic equipment by lead and is linked to each other.
In this utility model device, described electrode slice is to be made by the conducting metal disk, and 0.4mm is thick, diameter is 20-50mm.
In this utility model device, described rubber washer thickness diameter is 3mm, and the circle diameter is 41mm.
In this utility model device, have the hole that diameter is 25mm in the middle of the described circular laser circuit plate.
In this utility model device, edge, described cabinet front is provided with two fixedly ear grooves of 90 pasters of spending of being separated by.
In this utility model device, described paster is the thick 1mm of ear groove groove fixedly.
In this utility model device, described drug storage ware paster is a spill aluminum matter book sheet with conducting function, two pasters that its edge inserts the cabinet surface are fixedly in the ear groove, drug storage ware paster keeps physics to contact with electrode slice, is placed with the gel film that can immerse medicinal liquid in the drug storage ware paster.
In this utility model device, described spill aluminum matter book sheet thickness 0.9mm.
In this utility model device, described gel film is the pie type that netted silk material is made.
This utility model device is stained with the electrode slice that the conducting metal disk is made with ultrasonic transducer with the insulation viscose glue in the ambroin shell, make electrode slice as ultrasonic vibration unit, and output vibrating machine energy promotes and the contacted drug storage ware of electrode slice paster; Drug storage ware paster is a spill aluminum matter book sheet with conducting function, two pasters that its edge inserts the insulation crust surface are fixedly in the ear groove, thereby firmly keep physics to contact with metal electrode film, place the gel film that can immerse medicinal liquid in the drug storage ware paster, it contacts with human body skin; The mechanism of vibrating electrode sheet penetrates human body with medicament.The material of gel film, thickness and diameter are selected to be directed to human body to press close to skin part, make deformation can not occur and contact bad situation.Simultaneously and the contacted drug storage ware of electrode slice paster also be an electrode of electric field, this electrode is applied to human body with electroporation and two kinds of electrical stimulation signals of electric field of therapeutic equipment, improves the effect of administration.In addition, in the device the inside four laser diodes are installed, there is laser driver circuit board the inside, laser diode is sent continue or intermittent light beam, is transmitted on the skin by device (probe) shell, and assistant medicament is to the infiltration of human body.Two of designs are used for the fixedly ear groove of paster above the probe, not only make drug storage ware paster paste operation easy, and make drug storage ware paster and electrode slice keep favorable mechanical to contact with electrical property.
Technical schematic diagram of the present utility model as shown in Figure 1.The electrode of ultrasonic transducer is connected with the ultrasound drive signals of therapeutic equipments, and the vibrational energy output face is linked to be a rigid unitary by insulation viscose glue 9 and electrode slice, thereby makes the electrode slice vibration.Electrode slice is that 0.4mm is thick, diameter is the metal disk of 20-50mm, electric field, the electroporation signal of it and therapeutic instrument are connected, act on human body skin by being placed on its surperficial aluminum matter drug storage ware paster 8 and the medicament that is adsorbed on the gel film 12, strengthen penetrating of medicament.The laser drive circuit of four laser diodes 11 and therapeutic instrument is connected, and sends to continue and the laser beam of 650nm intermittently.
The beneficial effects of the utility model are, have realized that ultrasound wave, electroporation, electric field and four kinds of modes of laser realize comprehensive transdermal, and transdermal is effective; Paster fixedly be a pretty troublesome operation, general operation is easy to generate distortion, this utility model adopts the design of ear groove, is easy to that paster is inserted the ear groove and keeps well contact with electrode slice, thereby use simple and conveniently, maintenance is simply; The geometry of probe (device) and size meet principle of human engineering according to the design of statistics case, contact comfortable with human body.
Description of drawings
Below in conjunction with drawings and Examples this utility model is further specified.
Fig. 1 acousto-optic electricity helps skin location transdermal schematic diagram of device;
Fig. 2 is the front schematic view of this utility model material object;
Fig. 3 is the schematic rear view of this utility model material object;
Fig. 4 is this utility model structure side view;
Fig. 5 is this utility model structure front view;
Fig. 6 is this utility model structure top view;
Fig. 7 is that this utility model is used legend;
Among the figure: 1-electrode slice, 2-rubber washer, 3-cabinet, 4-circuit board presser feet, 5-laser circuit plate, 6-lead, the 7-paster is the ear groove fixedly, the rubberizing of insulating of 8-drug storage ware paster, 9-, the 10-ultrasonic transducer, 11-laser diode, 12-gel film, 13-transdermal therapeutic instrument, 14-degree of tightness band, 15-when injected organism tissue position, 16-acousto-optic electricity helps skin location transdermal device, 17-probe.
The specific embodiment
This utility model acousto-optic electricity helps skin location transdermal device example structure shown in Fig. 4,5,6, and this device comprises: electrode slice 1, rubber washer 2, cabinet 3, laser circuit plate 5, drug storage ware paster 8, insulation rubberizing 9, ultrasonic transducer 10, laser diode 11; Electrode slice 1 is bonding by insulation viscose glue 9 and ultrasonic transducer 10, place cabinet 3 the insides, the one side of described electrode slice is fixed by the shell edge, placing the thickness diameter at the edge of another side is 3mm, the circle diameter is 41mm, the rubber washer 2 that elasticity is good does not influence the normal vibration of electrode slice energy; The circular laser circuit plate 5 that 4 laser diodes 11 are installed be pressed in rubber washer 2 above, have the hole that diameter is 25mm in the middle of the ring circuit plate, guarantee circular laser circuit plate 5 contacts of ultrasonic transducer 10 discord and be in free movement state, the position of 4 laser diodes be dispersed in electrode slice 1 around, drug storage ware paster 8 is fixed on the electrode slice 1 and the electrode slice surface keeps excellent contact, and does not cover the laser diode light beam; The electric wire of described electrode slice, ultrasonic transducer and laser diode is drawn with therapeutic equipment by lead 6 and is linked to each other.
Edge, cabinet 3 front is provided with two fixedly ear grooves 7 of 90 pasters of spending of being separated by, the thick 1mm of groove.Thickness be 0.9mm aluminum matter drug storage ware paster 8 the edge by be inserted into these two pasters fixedly ear groove 7 be fixed on the electrode slice 1 and and electrode slice surface maintenance excellent contact.Be placed with the gel film that can immerse medicinal liquid in the drug storage ware paster.
Shown in Figure 7, be this utility model application examples.The medicament that doctor formula is left is injected into 12 li of gel films, and gel film is to make the pie type with the netted silk material that can contact with skin safe, has the adsorptive liquid function, is placed on drug storage ware paster (8) lining.Then with paster fixedly ear groove 7 insertions of drug storage ware paster 8 edges facing to probe (this utility model device), then whole probe is attached to the when injected organism tissue position 15 that human body needs the transdermal treatment, generally be that 17 pairings of two probes are used simultaneously during use, because probe and human body do not have absorption affinity, in order to prevent that probe from coming off, need probe be fixed on therapentic part with medical proof fabric, special circumstances need rubber-like degree of tightness band 14 that these two probes are tied up lightly on human body (as arm), probe is contacted well with human body skin, the connecting line 6 of will popping one's head at last is inserted on the plug of transdermal therapeutic instrument 13, and instrument energising beginning is to the human body transdermal.
Claims (9)
1. an acousto-optic electricity helps skin location transdermal device, it is characterized in that this device comprises: electrode slice (1), rubber washer (2), cabinet (3), laser circuit plate (5), drug storage ware paster (8), insulation rubberizing (9), ultrasonic transducer (10), laser diode (11); Electrode slice (1) is bonding by insulation viscose glue (9) and ultrasonic transducer (10), place cabinet (3) the inside, the one side of described electrode slice is fixed by the shell edge, be placed with rubber washer (2) at the edge of another side, the circular laser circuit plate (5) that 4 laser diodes (11) are installed be pressed in rubber washer (2) above, guarantee ultrasonic transducer (10) the circular laser circuit plate of discord (5) contact and be in free movement state, the position of 4 laser diodes be dispersed in electrode slice (1) around, drug storage ware paster (8) is fixed in electrode slice (1) upward and the electrode slice surface keeps excellent contact, and does not cover the laser diode light beam; The electric wire of described electrode slice, ultrasonic transducer and laser diode is drawn with therapeutic equipment by lead (6) and is linked to each other.
2. acousto-optic electricity according to claim 1 helps skin location transdermal device, it is characterized in that described electrode slice is to be made by the conducting metal disk, and 0.4mm is thick, diameter is 20-50mm.
3. acousto-optic electricity according to claim 1 helps skin location transdermal device, it is characterized in that described rubber washer (2) thickness diameter is 3mm, and the circle diameter is 41mm.
4. acousto-optic electricity according to claim 1 helps skin location transdermal device, it is characterized in that, has the hole that diameter is 25mm in the middle of the described circular laser circuit plate (5).
5. acousto-optic electricity according to claim 1 helps skin location transdermal device, it is characterized in that, cabinet (3) edge, front is provided with two fixedly ear grooves (7) of 90 pasters of spending of being separated by.
6. acousto-optic electricity according to claim 5 helps skin location transdermal device, it is characterized in that described paster is the thick 1mm of ear groove (7) groove fixedly.
7. acousto-optic electricity according to claim 1 helps skin location transdermal device, it is characterized in that, described drug storage ware paster (8) is a spill aluminum matter book sheet with conducting function, two pasters that its edge inserts cabinet (3) surface are fixedly in the ear groove (7), drug storage ware paster keeps physics to contact with electrode slice, and drug storage ware paster (8) lining is placed with the gel film (12) that can immerse medicinal liquid.
8. acousto-optic electricity according to claim 7 helps skin location transdermal device, it is characterized in that described spill aluminum matter book sheet, thickness 0.9mm.
9. acousto-optic electricity according to claim 7 helps skin location transdermal device, it is characterized in that the pie type that described gel film (12) is made for netted silk material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320089161 CN203154602U (en) | 2013-02-27 | 2013-02-27 | Skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320089161 CN203154602U (en) | 2013-02-27 | 2013-02-27 | Skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field |
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| Publication Number | Publication Date |
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| CN203154602U true CN203154602U (en) | 2013-08-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201320089161 Expired - Lifetime CN203154602U (en) | 2013-02-27 | 2013-02-27 | Skin positioning transdermal delivery device assisted by ultrasonic wave, laser and electric field |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139427A (en) * | 2016-08-05 | 2016-11-23 | 广州市艾生维医药科技有限公司 | The fixing patch of ultrasonic therapeutic |
| CN107334489A (en) * | 2017-08-15 | 2017-11-10 | 安隽医疗科技(南京)有限公司 | A kind of ultrasonic coupling paster |
| CN108211106A (en) * | 2018-01-16 | 2018-06-29 | 南京医科大学 | A kind of ultrasonic medicinal adjuvant therapy device |
| CN108744259A (en) * | 2018-06-19 | 2018-11-06 | 南京奥珂森电子有限公司 | Ultrasonic conductance fixes patch |
| CN109011130A (en) * | 2018-05-29 | 2018-12-18 | 上海大学 | A kind of percutaneous photoelectricity driving ion medicine conveying device based on nanoneedle |
| CN111467666A (en) * | 2020-03-20 | 2020-07-31 | 西安交通大学第二附属医院 | Ultrasonic medicine feeding device |
| CN112089975A (en) * | 2020-04-26 | 2020-12-18 | 未来穿戴技术有限公司 | Massage assembly for massage apparatus and massage apparatus |
| CN112654300A (en) * | 2018-09-04 | 2021-04-13 | 皇家飞利浦有限公司 | Support unit for medical imaging element |
| CN112933390A (en) * | 2021-01-19 | 2021-06-11 | 温州市中西医结合医院 | Ultrasonic medicine introducing therapeutic apparatus for tonsil |
| CN113546314A (en) * | 2020-04-26 | 2021-10-26 | 未来穿戴技术有限公司 | Neck massager, massage head for neck massager and conductive gel assembly of massage head |
| CN113546313A (en) * | 2020-04-26 | 2021-10-26 | 未来穿戴技术有限公司 | Neck massager, massage head assembly for neck massager and gel sleeve of massage head assembly |
| CN113712664A (en) * | 2021-08-23 | 2021-11-30 | 围美健康科技有限公司 | Laser dot matrix intelligent skin physiotherapy instrument based on electric pore forming and intelligent skin physiotherapy method thereof |
-
2013
- 2013-02-27 CN CN 201320089161 patent/CN203154602U/en not_active Expired - Lifetime
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139427B (en) * | 2016-08-05 | 2019-03-19 | 广州市艾生维医药科技有限公司 | The fixed patch of ultrasonic therapy |
| CN106139427A (en) * | 2016-08-05 | 2016-11-23 | 广州市艾生维医药科技有限公司 | The fixing patch of ultrasonic therapeutic |
| CN107334489A (en) * | 2017-08-15 | 2017-11-10 | 安隽医疗科技(南京)有限公司 | A kind of ultrasonic coupling paster |
| CN108211106A (en) * | 2018-01-16 | 2018-06-29 | 南京医科大学 | A kind of ultrasonic medicinal adjuvant therapy device |
| CN109011130A (en) * | 2018-05-29 | 2018-12-18 | 上海大学 | A kind of percutaneous photoelectricity driving ion medicine conveying device based on nanoneedle |
| CN108744259A (en) * | 2018-06-19 | 2018-11-06 | 南京奥珂森电子有限公司 | Ultrasonic conductance fixes patch |
| CN112654300A (en) * | 2018-09-04 | 2021-04-13 | 皇家飞利浦有限公司 | Support unit for medical imaging element |
| CN111467666A (en) * | 2020-03-20 | 2020-07-31 | 西安交通大学第二附属医院 | Ultrasonic medicine feeding device |
| CN112089975A (en) * | 2020-04-26 | 2020-12-18 | 未来穿戴技术有限公司 | Massage assembly for massage apparatus and massage apparatus |
| CN113546314A (en) * | 2020-04-26 | 2021-10-26 | 未来穿戴技术有限公司 | Neck massager, massage head for neck massager and conductive gel assembly of massage head |
| CN113546313A (en) * | 2020-04-26 | 2021-10-26 | 未来穿戴技术有限公司 | Neck massager, massage head assembly for neck massager and gel sleeve of massage head assembly |
| CN112933390A (en) * | 2021-01-19 | 2021-06-11 | 温州市中西医结合医院 | Ultrasonic medicine introducing therapeutic apparatus for tonsil |
| CN113712664A (en) * | 2021-08-23 | 2021-11-30 | 围美健康科技有限公司 | Laser dot matrix intelligent skin physiotherapy instrument based on electric pore forming and intelligent skin physiotherapy method thereof |
| CN113712664B (en) * | 2021-08-23 | 2022-07-29 | 围美健康科技有限公司 | Laser dot matrix intelligent skin physiotherapy instrument based on electric hole forming |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130828 |