CN113712664A - Laser dot matrix intelligent skin physiotherapy instrument based on electric pore forming and intelligent skin physiotherapy method thereof - Google Patents
Laser dot matrix intelligent skin physiotherapy instrument based on electric pore forming and intelligent skin physiotherapy method thereof Download PDFInfo
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Abstract
The invention provides an intelligent laser dot matrix skin physiotherapy instrument based on electroporation, which comprises a physiotherapy probe with a dep area, a dot matrix laser area and a drug delivery area, a cable and a host, wherein the physiotherapy probe is provided with a shell, one end of the shell is a physiotherapy end, the other end of the shell is a cable leading-out end, the cable is connected with the host, so that the host computer can control the physiotherapy probe and carry out skin physiotherapy, the LRT who has realized dep and has produced carries out laser energy conduction, the wound drawback of having avoided traditional laser dot matrix, use intelligent image recognition model to carry out laser physiotherapy and realize the errorless of dot matrix laser to pathological change position, select percutaneous administration to give the extra skin maintenance efficiency on the laser physiotherapy basis, can freely select traditional dep or the independent physiotherapy scheme of laser dot matrix, or mix the physiotherapy mode, realize that the multiple customization of user's physiotherapy scheme is selected.
Description
Technical Field
The invention relates to a laser dot matrix skin physiotherapy instrument, in particular to a laser dot matrix intelligent skin physiotherapy instrument based on electric pore forming and an intelligent physiotherapy method thereof, and belongs to the field of skin physiotherapy instruments.
Background
Electroporation (dep) is a technique for skin care that is fast and efficient by simultaneous administration of high voltage pulses to the skin to create temporary reversible ion transport channels (LTRs) in the stratum corneum of the skin. The laser lattice is acted on the skin by high-energy pulse lattice laser to generate a linear micropore channel similar to the skin surface, so that photons can reach the dermis of the skin deeply, thermal solidification is generated around the hole to form a stable straight-through hole, heat energy is transferred around the straight-through hole to be used for subcutaneous pigments or blood vessels, color spots and abnormally distributed capillaries are decomposed, and the capillaries are dredged to achieve the effect of beautifying.
However, the direct hole generated by the lattice laser is a skin wound, needs to be self-repaired by skin cells, undergoes inflammation proliferation and remodeling stages, and is inevitably generated with side effects and poor repair in the three processes, and the LTR generated by the electric pore-forming belongs to a temporary ion hydrophilic channel, is restored by rearrangement of stratum corneum cells for a period of time after being opened, and belongs to a real non-invasive technology.
From the technical aspect, the dot matrix laser changes the emission mode through an image generator (CPG) to form various geometric patterns to act on the skin. However, the part of the skin surface needing repair can not be covered completely by simple geometric figures, and some healthy parts do not need physical therapy, but are usually also acted by laser micro-beams to generate coverage errors. So that the lattice laser can not be used for pertinently selecting the part needing physical therapy.
In the prior art, the penetration is promoted by introducing ultrasonic waves after dot matrix laser, but the combined technology only promotes the penetration of drugs and does not have the physical therapy effects of quickly removing freckles and decomposing melanin. Therefore, if the noninvasive property of dep can be utilized and the rapid thermal effect of the lattice laser is combined, on one hand, the rapid drug delivery can be realized, on the other hand, the pigmented spots in the skin can be efficiently eliminated, and the multiple effects of nourishing, treating and beautifying can be realized. Considering that the hole size of LTR (5-100 μm) and the hole size of lattice laser (typically about 120 μm) is the size of the latter covering the former, if the laser can be introduced into the LTR around the part needing therapy, on one hand, the thermal effect is generated, and simultaneously, the advantage of the temporary LTR can be utilized, the noninvasive closure recovery is realized, and the lattice laser is generated by selectively covering the part needing therapy, so that the true noninvasive intelligent skin therapy is realized.
Disclosure of Invention
In order to overcome the above disadvantages of the prior art, the present invention considers three aspects, the selective generation of the first electroporation hole, how to select the part needing physical therapy by the second lattice laser, and the improvement of the energy of the laser. And (3) a third administration process.
Therefore, the invention provides an intelligent laser dot matrix skin physiotherapy instrument based on electric pore forming, which comprises a physiotherapy probe, a cable and a host, wherein the physiotherapy probe is provided with a shell, one end of the shell is a physiotherapy end, the other end of the shell is a cable leading-out end, and the cable is connected with the host so that the host can control the physiotherapy probe to carry out skin physiotherapy.
Furthermore, a dep area, a dot matrix laser area and a dosing area around or inside the dep area, which are arranged at the physical therapy end, are respectively communicated with one end of a dep cavity, a dot matrix laser cavity and a dosing cavity which are formed by dividing the shell;
a dep device is arranged in the dep cavity and used for acting on a part needing physical therapy through a dep area to generate LTR;
the dep device is provided with at least one three-dimensional dep probe protruding out of the dep area and used for adhering to the skin to perform electric pulse action, and preferably, the voltage parameter: the pulse frequency is 1-2.5Hz, and the pulse voltage is 25-200V;
the laser dot matrix module comprises a dot matrix control module with an n x m laser rectangular dot matrix or a multi-pixel circular laser dot matrix or a multi-pixel other regular geometric figure laser dot matrix, the dot matrix control module is electrically connected with the skin imaging device and is used for controlling the n x m laser dot matrix or the multi-pixel circular laser dot matrix or the multi-pixel other regular geometric figure laser dot matrix to act on a part needing physical therapy according to a skin surface image transmitted by the skin imaging device; optionally, n, m is selected between 7-200. Laser parameters: power: no more than 20W, laser working mode: including continuous mode, super-pulse mode, intermittent mode, pulse energy: 1mJ-100mJ, energy interval 1.5-2mJ, focal spot diameter: 50 μm to 1000 μm, pulse width: 0.1ms-10 ms
Optionally, the lattice control module includes an image acquisition module, an image processing module, and a lattice excitation module, wherein the image acquisition module is configured to acquire an image captured by the skin imaging device, the image processing module is configured to perform zoning on the acquired image, identify a part in which physical therapy is required, and generate a control signal, and the lattice excitation module controls a laser lattice or a multi-pixel circular laser lattice or other regular geometric laser lattices in an n × m laser lattice or nearby part that requires physical therapy according to the control signal to emit pulse laser to act on the part, so that the pulse laser at least partially acts on a skin stratum corneum and skin tissue below the skin stratum corneum through LTR to selectively perform physical therapy on the skin.
The image processing module comprises an image recognition unit and a control signal generation unit, the image recognition unit performs graying according to the acquired image, divides the grayed image into a plurality of areas to form a plurality of sub-images, recognizes that the area where the sub-image is located is used as a physical therapy area if the total gray value g in each sub-image is smaller than a preset value, the signal generation unit generates a control signal according to the physical therapy area in the grayed image only and sends out the control signal, and the control signal generation unit triggers the dot matrix excitation module to start according to the control signal of the physical therapy area where the control signal originates in the plurality of areas so as to excite the laser dot matrix where the physical therapy area is located to work to generate laser to act on the physical therapy area;
optionally, the preset value is an average value of total gray-scale values of corresponding grayed-out images of the acquired image of at least one healthy skin area of the detection subject, and the average value is any one of an arithmetic average value and a weighted average value. The at least one healthy skin area may be determined according to a physical therapist's advice and/or user's discretion.
It will be appreciated that complete coverage is achieved when a benign skin lesion such as a color spot is located completely within the sub-image region, and the total value of the grey scale is lower than when the same benign skin lesion is located partially within the sub-image region. And when the benign skin lesion is located in the plurality of sub-image regions, the gray value of each sub-image is smaller than a preset value, and all laser dot matrixes in the sub-image regions need to be excited to perform physical therapy on the regions in a targeted manner, so that the complete coverage of the benign skin lesion and the regions nearby the benign skin lesion is realized, and the accurate coverage of the benign skin lesion is realized on the whole.
In one embodiment, the image recognition unit further comprises an intelligent image recognition unit, wherein the intelligent image recognition unit establishes an artificial intelligence model according to the sub-image of the physiotherapy region of the grayed image and the control signal, the artificial intelligence model recognizes whether the control signal needs to be generated according to the sub-image, the artificial intelligence model comprises any one of a Convolutional Neural Network (CNN), a Support Vector Machine (SVM) and a generation countermeasure network (GAN), and the CNN can recognize a corresponding control signal code, namely 1 (generation) or 0 (non-generation), according to the sub-image, so as to recognize whether each sub-image needs to generate a corresponding control signal. The SVM belongs to a classification algorithm, and classifies a plurality of sub-images into a control signal code 1 or 0. And the GAN generates a pseudo gray-scale map according to the randomly generated gray-scale map and the preset value, judges whether the gray-scale map belongs to the control signal code 1 or 0 by utilizing a plurality of sub-images, and identifies a corresponding correct code when the pseudo gray-scale map is continuously corrected to be close to a plurality of real sub-images.
If the gray value of the sub-image is consistent with the position of the generated control signal identified by artificial intelligence, the former scheme is adopted, and if the gray value of the sub-image is not consistent with the position of the generated control signal identified by artificial intelligence, one algorithm of the algorithms is set by a user through a host in advance, and the latter algorithm is preferred.
Preferably, the control signal generating unit includes a microprocessor or a single chip microcomputer. The areas are n x m multi-pixel matrix areas or multi-pixel circular laser dot matrixes or multi-pixel other regular geometric figures.
Optionally, the skin imaging device is disposed in the lattice laser region or the other end of the lattice laser cavity opposite to the lattice laser region, or between the lattice laser region and the other end of the lattice laser cavity, together with the n × m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice, and the skin imaging device is located at the geometric center of the n × m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice.
Preferably, the skin imaging device comprises a camera, preferably a high definition pinhole camera, and an illumination unit for illuminating the site.
Preferably, at least one of the dep region, the lattice laser region, and the administration region around the dep region is formed of a transparent material as at least a part of the housing, and more preferably, the lattice laser region is formed of a transparent material.
The drug delivery cavity is internally provided with a drug delivery device used for delivering drug to the LTR and/or the LTR subjected to the laser dot matrix; preferably, the dep cavity and the administration cavity are arranged adjacently and hermetically, and the periphery of the three-dimensional dep probe is provided with an administration hole communicated with the administration device, so that the medicament permeates the skin through the administration hole and the LTR and/or the LTR acted by the laser lattice to perform physiotherapy.
The cable comprises a first power line connected with the dep device, a first signal line for controlling the working of the dep device, a second power line connected with the laser dot matrix module and the skin imaging device, a second signal line for controlling the working of the laser dot matrix module and the skin imaging device, a third power line connected with the drug delivery device and a third signal line for controlling the working of the drug delivery device, wherein the first power line and the third power line are respectively combined into a first cable and a third cable in a shielding mode from the first signal line and the third signal line, and the first cable and the third cable are respectively and independently three cables.
The host comprises a display screen, three cable interfaces used for connecting a first cable and a third cable, and a processor used for controlling the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, parameter setting of the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device and physical therapy data acquisition and analysis of the dep device, the laser dot matrix module, the skin imaging device and the drug delivery device, so that intelligent skin physical therapy is realized. The physical therapy data comprises images collected by the skin imaging device, user information and skin general profiles of each physical therapy, and physical therapy process data (including dep, laser dot matrix, use conditions of each drug administration device, and the parameters). Wherein said parameters are well known to the skilled person, such as voltage parameters, laser parameters, and the type of administration, speed, mode of administration, continuous or pulsed form, and corresponding parameters.
Preferably, the main body further includes a moving bracket having a function of conveniently moving the main body. Specifically, the mobile stand has a plurality of casters.
The invention also provides an intelligent skin physiotherapy method of the laser dot matrix intelligent skin physiotherapy instrument based on the electric pore forming, which is characterized in that the method uses the laser dot matrix intelligent skin physiotherapy instrument based on the electric pore forming, and comprises the following steps:
(1) selecting a mode of the needed physical therapy: the system comprises an individual dep physiotherapy mode, an individual laser dot matrix physiotherapy mode and a laser dot matrix mixed physiotherapy mode based on electroporation, wherein when the individual dep physiotherapy mode and the individual laser dot matrix physiotherapy mode are selected, the host is used for individually selecting the corresponding physiotherapy mode and using the physiotherapy probe to perform corresponding physiotherapy, the individual dep physiotherapy mode is matched with a drug delivery device to deliver drug during or after a specified first time under the action of an electric pulse with set parameters, and the individual laser dot matrix physiotherapy mode completes physiotherapy within a specified second time or controls the drug delivery device to deliver drug during or after the specified second time according to the action of the laser pulse with the set laser parameters; if the laser lattice mixed physiotherapy mode based on the electric pore forming is adopted, entering the step (2); the first and second time is 1min-1 h.
(2) Firstly dep is carried out at a first time to generate LRT, then laser dot matrix is used for acting on an area acted by the dep at a second time, the skin imaging device shoots an image of the area acted by the dep, the laser dot matrix module carries out selective physiotherapy on the area acted by the dep, and then step (3) is carried out selectively according to skin conditions; preferably, the laser lattice is selected according to the desired laser parameters to be used, which are selected such that no or no through holes through the dermis are created.
It will be appreciated that when selecting laser parameters that do not produce through holes, at least a portion of the laser beam is delivered to deeper skin layers by converting energy into heat in the LRT formed in the benign lesion and its vicinity, producing a therapeutic effect that breaks down the benign lesion, and does not produce a perforating effect on the skin, such that the LRT substantially restores the original state of the skin by reversibly self-closing in a short period of time, and an additional therapeutic effect if administered simultaneously before self-closing.
(3) And the drug delivery device for controlling the selected parameters delivers the drug to the skin area subjected to dep and laser dot matrix physiotherapy for a third specified time to finish physiotherapy, wherein the third time is 0.1-10 min.
Preferably, after the hybrid physiotherapy mode is selected, the physiotherapy instrument prohibits the actuation of the drug delivery device during dep and spot laser actions.
In one embodiment, after dep generation LRT at the first time, the step (2-1) of using the laser lattice to perform the dep acting region at the second time is further included: penetrating the photosensitizer to the action area for a fourth time through the administration device, and applying physiological saline or medical alcohol to the action area through the administration device to clean residual photosensitizer, so that the fluorescent agent penetrating into the LRT can be captured by a fluorescence image shot by the skin imaging device, and a control signal is generated by calculating the total gray value of the collected image area, gray level and sub-image gray level or identifying the control signal by adopting the artificial intelligence model aiming at the gray level image. Thus, the LRT falling within the sub-image area can be selectively irradiated with the pulsed laser light, so that at least part of the pulsed laser light can enter the LRT. The fourth time is 3-20s, the photosensitizer is phytochrome, preferably, the phytochrome is chlorophyll.
The invention also provides a non-transitory storage medium, in which a computer readable program executable by the processor to implement the above-mentioned laser lattice intelligent skin physical therapy method based on electroporation is stored.
Advantageous effects
(a) Realizes the laser energy conduction of LRT generated by dep, avoids the trauma defect of the traditional laser dot matrix,
(b) the intelligent image recognition model is used for carrying out laser physical therapy aiming at the lesion part to realize the error-free coverage of the dot matrix laser,
(c) selects the additional skin care efficacy of the transdermal drug delivery on the basis of laser physical therapy,
(d) the traditional dep or laser dot matrix single physical therapy scheme or the mixed physical therapy mode can be freely selected, and various customized selections of the physical therapy scheme of the user are realized.
Drawings
FIG. 1 shows an embodiment of the intelligent skin physiotherapy equipment based on laser lattice of electric pore-forming,
fig. 2, one embodiment of the structure of the physio-probe of the present invention,
FIG. 3 is a schematic diagram of a 6 x 17 pixel skin image acquired by graying of the present invention,
FIG. 4 is a graph showing the comparative effects before (a) and after (b) on the face of the subject before and after the mixed treatment mode,
wherein reference numeral 1 is based on the intelligent skin physiotherapy equipment of laser dot matrix of electricity porogenesis, 2dep district, 3 dot matrix laser areas, 4 dosing areas, 57 x 16 laser rectangle dot matrix control module, 6 cameras, 7 lighting unit, 8 image acquisition modules, 9 image processing modules, 10 first cables, 11 second cables, 12 third cables, 13 movable support, 14 truckles, 21dep chamber, 31 dot matrix laser cavity, 41 dosing chambers, 211 three-dimensional dep probe, 411 dosing holes.
Detailed Description
Example 1
Fig. 1 shows a laser lattice intelligent skin physiotherapy instrument 1 based on electric pore-forming according to this embodiment, which includes a physiotherapy probe 1-0, a first cable 10, a second cable 11, and a cable combination of a third cable 12, and a host 1-1, wherein the physiotherapy probe 1-0 has a housing, one end of the housing is a physiotherapy end, the other end is a cable combination leading-out end, and the first cable 10, the second cable 11, and the third cable 12 are connected with the host 1-1, so that the host 1-1 can control the physiotherapy probe to perform skin physiotherapy.
As shown in fig. 2, the therapy end has a dep region 2, a dot matrix laser region 3 and an administration region 4 inside the dep region 2, which are respectively communicated with one end of a dep cavity 21, a dot matrix laser cavity 31 and an administration cavity 41 which are divided in the shell; the lattice laser area 3 is formed of transparent organic glass.
A dep device is arranged in the dep cavity 21 and is used for acting on a part needing physical therapy through a dep area 2 to generate LTR as shown in figure 3;
the dep device is provided with four three-dimensional dep probes 211 protruding out of the dep area 2 and used for being attached to the skin to perform electric pulse action, and the voltage parameters are as follows: the pulse frequency is 2Hz, and the pulse voltage is 100V;
the laser dot matrix module and the skin imaging device are installed in the dot matrix laser cavity 31, wherein the laser dot matrix module comprises a 7 x 16 laser rectangular dot matrix control module 5, the skin imaging device further comprises a camera 6 and an illuminating unit 7 used for illuminating the part, and the camera 6 is a high-definition pinhole camera.
The camera 6 is arranged together with the 7 x 16 rectangular array of laser light at the other end of the matrix laser cavity opposite to the matrix laser area 3, and the camera 6 is in the center position of the 7 x 16 rectangular array of laser light (as shown in fig. 2).
The dot matrix control module 5 is electrically connected with the skin imaging device and is used for controlling the 7 x 16 laser rectangular dot matrix to act on an area needing physical therapy according to a skin surface image (shown in figure 3) transmitted by the skin imaging device; laser parameters: power: 15W, laser working mode: including continuous mode, super-pulse mode, intermittent mode, pulse energy: 8mJ focal spot diameter: 120um, pulse width: 1 ms.
The dot matrix control module 5 comprises an image acquisition module 8, an image processing module 9 and a dot matrix excitation module (not shown), wherein the image acquisition module 8 is used for acquiring images shot by the camera 6, the image processing module 9 is used for dividing the acquired images, identifying parts in the parts which need physical therapy and generating control signals, and the dot matrix excitation module controls laser dot matrixes in the parts which need physical therapy and 7 x 16 laser dot matrixes near the parts to emit pulse laser to act on the parts according to the control signals, so that the pulse laser at least partially acts on skin cuticle and skin tissues below the skin cuticle through LTR to selectively perform physical therapy on the skin.
The image processing module 9 comprises an image recognition unit and a control signal generation unit (not shown), said image recognition unit grays the acquired image, divides the grayed image into a plurality of regions to form a plurality of sub-images (as shown in figure 3), and identifying if g of the total gray level value g in each sub-image is less than the arithmetic mean of the total gray level values of the corresponding grayed images of the images acquired by the at least one healthy skin area, the area where the sub-image is located is taken as a physical therapy area, the signal generating unit generates the control signal only according to the physical therapy area in the grayed image, and sends out a control signal, the control signal generating unit triggers the dot matrix excitation module to start according to the coordinates of the physical therapy region from which the control signal originates in the plurality of regions, thereby exciting the laser lattice where the physical therapy area is located to work to generate laser to act on the physical therapy area. The control signal generating unit is a single chip microcomputer.
A drug delivery device is arranged in the drug delivery cavity 41 and is used for delivering drug to the LTR and the LTR subjected to the laser dot matrix; the dep cavity 21 and the administration cavity 41 are arranged in a mutually sealed mode (not shown), and the middle parts of the four three-dimensional dep probes 211 are provided with an administration hole 411 communicated with the administration device, so that the medicament can permeate the skin through the administration hole by means of LTR and LTR under the action of laser lattice for physiotherapy.
The host 1 comprises a display screen 1-1-1, three cable interfaces for connecting a first cable 10, a second cable 11 and a third cable 12, and a processor (not shown) for controlling the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, parameter setting of the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, the three devices, and acquisition and analysis of physical therapy data to realize intelligent skin physical therapy.
The physical therapy data comprises images collected by the skin imaging device, user information and skin general profiles of each physical therapy, physical therapy process data including dep, laser dot matrix, use conditions of each drug administration device, and the parameters.
The main body 1-1 further includes a moving stand 13 having a function of conveniently moving the main body. The mobile carriage 13 has four castors 14.
Example 2
The present embodiment is different from embodiment 1 in terms of image processing, wherein the image recognition unit includes an intelligent image recognition unit (not shown), the intelligent image recognition unit establishes an artificial intelligence model according to a sub-image of a therapy region of the grayed image and the control signal, the artificial intelligence model recognizes whether a control signal needs to be generated according to the sub-image, the artificial intelligence model includes a convolutional neural network CNN, and the CNN can recognize a corresponding control signal code, i.e., 1 (generated) or 0 (not generated), according to the sub-image, so as to recognize whether each sub-image needs to generate a corresponding control signal.
As shown in fig. 3, in the captured image subjected to the grayscale image of the dep selection process, A, B, C, D four kinds of the color patches occupying different numbers (4, 2, 1, and 3, respectively) of sub-images, and the cases of the plurality of LRT distributions distributed in the vicinity of the color patches and in the non-color-patch sub-images are exemplarily given. Because LRT is temporarily reversible and self-closed, when the dot matrix laser intelligently identifies 10 sub-image areas in four color spots according to an image by adopting a CNN model to generate a control signal and excites a corresponding dot matrix to generate laser pulse with set parameters, a laser part can enter the LRT to generate heat accumulation and transmit the heat accumulation to deep skin to decompose the color spots, the LRT can continue to pass through the inner layer of the skin deeply according to different laser parameter adjustments, more effective decomposition is generated, and simultaneously, because other sub-image areas have no laser pulse effect, the LRT and the LRT in the color spot areas are administrated together to further maintain the skin, so that an additional physical therapy effect is achieved.
Example 3
The physical therapy mode comprises the following steps: the system comprises an individual dep physiotherapy mode, an individual laser dot matrix physiotherapy mode and a laser dot matrix mixed physiotherapy mode based on electroporation, wherein when the individual dep physiotherapy mode and the individual laser dot matrix physiotherapy mode are selected, the host is used for individually selecting the corresponding physiotherapy mode and using the physiotherapy probe to perform corresponding physiotherapy, the individual dep physiotherapy mode is matched with a drug delivery device to deliver drug during or after a specified first time under the action of an electric pulse with set parameters, and the individual laser dot matrix physiotherapy mode completes physiotherapy within a specified second time or controls the drug delivery device to deliver drug during or after the specified second time according to the action of the laser pulse with the set laser parameters; if the laser lattice mixed physiotherapy mode based on the electric pore forming is adopted, entering the step (2); the first and second time is 1min-1 h.
(2) Firstly dep is carried out to generate LRT, then laser dot matrix is used for acting on an area acted by the dep, the skin imaging device shoots an image of the area acted by the dep, the laser dot matrix module carries out selective physical therapy on the area acted by the dep, and then the step (3) is selectively carried out according to skin conditions; preferably, the laser lattice is selected according to the desired laser parameters to be used, which are selected such that no or no through holes through the dermis are created.
It will be appreciated that when selecting laser parameters that do not produce through holes, at least a portion of the laser beam is delivered to deeper skin layers by converting energy into heat in the LRT formed in the benign lesion and its vicinity, producing a therapeutic effect that breaks down the benign lesion, and does not produce a perforating effect on the skin, such that the LRT substantially restores the original state of the skin by reversibly self-closing in a short period of time, and an additional therapeutic effect if administered simultaneously before self-closing.
(3) And the drug delivery device for controlling the selected parameters delivers the drug to the skin area subjected to dep and laser dot matrix physiotherapy for a third specified time to finish physiotherapy, wherein the third time is 0.1-10 min.
Example 4
The utility model provides a laser dot matrix intelligence skin physiotherapy physical therapy method based on electric pore hole which characterized in that, the method uses the laser dot matrix intelligence skin physiotherapy equipment based on electric pore hole of embodiment 3, includes:
(1) selecting a mode of the needed physical therapy: clicking and selecting the laser dot matrix mixing physiotherapy mode based on the electroporation on the screen 1-1-1 of the host machine 1-1, and then entering the step (2);
(2) firstly dep is carried out for 5min to generate LRT, then 20min laser dot matrix is used for acting on the region acted by the dep, the camera 6 shoots the image of the region acted by the dep, the laser dot matrix module 5 carries out selective physical therapy on the region acted by the dep, and then the step (3) is carried out according to skin conditions; the laser lattice is selected to be the laser parameter which does not generate a large amount of straight-through holes which are directly connected to the dermis according to the laser parameter which is selected to be used according to the requirement, namely the pulse energy is adjusted in 1-5mJ, and the working mode of the laser is the super-pulse mode.
(3) And controlling the selected parameters to perform the water replenishing and whitening prescription permeation on the skin area subjected to dep and laser dot matrix physiotherapy for a third specified time to complete physiotherapy, wherein the third time is 0.5 min.
Fig. 4(a) and 4(b) are comparison results of facial skin before and after (24 days) the treatment of the subject using the mixed treatment regimen, and it can be seen that the results are effective in removing freckles and whitening.
Example 5
The embodiment further comprises a step (2-1) before the dep acting region is performed for 20min by using the laser lattice after dep at the first time of 5min is performed to generate LRT on the basis of the embodiment 4: 20s of chlorophyll alcohol solution permeates into the action area through the drug delivery device, and then medical alcohol is applied to the drug delivery device for cleaning for 10-20s, so that plant pigment permeating into the LRT can be captured by a fluorescence image shot by a skin imaging device, and the total value of the image division, the gray scale and the sub-image gray scale acquired by the camera 6 is calculated to generate a control signal, or the control signal is identified by adopting a CNN model aiming at the gray scale image, so that the pulse laser only irradiates in the sub-image area with the LRT.
Claims (15)
1. The utility model provides a laser dot matrix intelligence skin physiotherapy equipment based on electricity hole is made, a serial communication port, including physiotherapy probe, cable and host computer, wherein the physiotherapy probe has the shell, shell one end is the physiotherapy end, and the other end is drawn forth the end for the cable, the cable is connected with the host computer to make the host computer can control the physiotherapy probe and carry out skin physiotherapy.
2. The intelligent skin physiotherapy instrument of claim 1, wherein the physiotherapy end has a dep region, a dot matrix laser region and a dosing region around or inside the dep region respectively communicated with one end of a dep cavity, a dot matrix laser cavity and a dosing cavity formed by segmentation in the housing;
a dep device is arranged in the dep cavity and used for acting on a part needing physical therapy through a dep area to generate LTR;
the dep device is provided with at least one three-dimensional dep probe protruding out of the dep area and used for being attached to the skin to perform electric pulse action, and the voltage parameters are as follows: the pulse frequency is 1-2.5Hz, and the pulse voltage is 25-200V;
the laser dot matrix module comprises a dot matrix control module with an n x m laser rectangular dot matrix or a multi-pixel circular laser dot matrix or a multi-pixel other regular geometric figure laser dot matrix, the dot matrix control module is electrically connected with the skin imaging device and is used for controlling the n x m laser dot matrix or the multi-pixel circular laser dot matrix or the multi-pixel other regular geometric figure laser dot matrix to act on a part needing physical therapy according to a skin surface image transmitted by the skin imaging device; wherein n and m are selected from 7 to 200, and the laser parameters are as follows: power: no more than 20W, laser working mode: including continuous mode, super-pulse mode, intermittent mode, pulse energy: 1mJ-100mJ, energy interval 1.5-2mJ, focal spot diameter: 50 μm to 1000 μm, pulse width: 0.1ms-10 ms;
the drug delivery cavity is internally provided with a drug delivery device used for delivering drug to the LTR and/or the LTR subjected to the laser dot matrix; the dep cavity and the dosing cavity are arranged adjacent to each other in a sealing mode, and the periphery of the three-dimensional dep probe is provided with a dosing hole communicated with the dosing device, so that the medicament can permeate the skin through the dosing hole and the LTR and/or LTR under the action of laser dot matrix for physiotherapy;
the cable comprises a first power line connected with the dep device, a first signal line for controlling the working of the dep device, a second power line connected with the laser dot matrix module and the skin imaging device, a second signal line for controlling the working of the laser dot matrix module and the skin imaging device, a third power line connected with the drug delivery device and a third signal line for controlling the working of the drug delivery device, wherein the first power line, the second power line, the third power line and the third signal line are respectively shielded and combined into a first cable, a second cable and a third cable, and the first cable, the second cable and the third cable are respectively independent into three cables;
the host comprises a display screen, three cable interfaces for connecting a first cable and a third cable, and a processor for controlling the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, parameter setting of the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device and physical therapy data acquisition and analysis of the dep device, the laser dot matrix module, the skin imaging device and the drug delivery device to realize intelligent skin physical therapy; the main frame further comprises a movable support which is provided with a plurality of casters and facilitates the movement of the main body.
3. The intelligent skin physiotherapy instrument of claim 2, wherein the dot matrix control module comprises an image acquisition module, an image processing module, and a dot matrix excitation module, wherein,
the image acquisition module is used for acquiring the image shot by the skin imaging device,
the image processing module is used for dividing the collected image, identifying the part which needs physical therapy and generating a control signal,
the lattice excitation module controls the laser lattice in the n x m laser lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice which is positioned at and/or near the part needing physical therapy according to the control signal to emit pulse laser to act on the part, so that the pulse laser at least partially acts on the skin stratum corneum and the skin tissue below the skin stratum corneum through LTR to selectively perform physical therapy on the skin.
4. The intelligent skin physiotherapy instrument of claim 3, wherein the image processing module comprises an image recognition unit and a control signal generation unit,
the image identification unit is used for carrying out graying according to the acquired image, dividing the grayed image into a plurality of areas to form a plurality of sub-images, identifying that the area where the sub-image is located is used as a physical therapy area if the total gray value g in each sub-image is smaller than a preset value, the signal generation unit is used for generating a control signal according to the physical therapy area in the grayed image only, and sending out the control signal, and the control signal generation unit is used for triggering the dot matrix excitation module to start according to the control signal of the physical therapy area where the control signal originates in the plurality of areas, so that the laser dot matrix where the physical therapy area is located is excited to work to generate laser to act on the physical therapy area;
the preset value is the average value of the total gray values of the corresponding grayed images of the acquired images of at least one healthy skin area of the detection object, the average value is any one of an arithmetic average value and a weighted average value, and the at least one healthy skin area is determined according to the recommendation of a physical therapy doctor and/or the self-selection of a user.
5. The intelligent skin physiotherapy instrument of claim 4, wherein the image recognition unit comprises an intelligent image recognition unit, the intelligent image recognition unit establishes an artificial intelligence model according to the sub-image of the physiotherapy area of the grayed image and the control signal, the artificial intelligence model recognizes whether the control signal needs to be generated according to the sub-image, the artificial intelligence model comprises any one of a Convolutional Neural Network (CNN), a Support Vector Machine (SVM) and a generation countermeasure network (GAN), so that the corresponding control signal code (1 or 0) can be recognized according to the sub-image, and whether the corresponding control signal needs to be generated for each sub-image is recognized.
6. The intelligent skin physiotherapy apparatus according to claim 5, wherein if the gray level value of the sub-image is consistent with the generated control signal position recognized by the artificial intelligence, the former scheme is adopted, and if not, one of the algorithms of the confidence acquisition is set by the user through the host in advance.
7. The intelligent skin physiotherapy instrument of any one of claims 4-6, wherein the control signal generation unit comprises a microprocessor or a single chip microcomputer, and the plurality of regions are n x m multi-pixel matrix regions or multi-pixel circular laser dot matrix or multi-pixel other regular geometric figures.
8. The intelligent skin physiotherapy instrument of claim 7, wherein the skin imaging device is disposed with the n x m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice at the other end of the lattice laser area or the lattice laser cavity opposite to the lattice laser area, or therebetween, and is at the geometric center position of the n x m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice, the skin imaging device comprising a camera and an illumination unit for illuminating the site.
9. The intelligent skin physiotherapy apparatus of claim 8, wherein said camera is a high-definition pinhole camera, and at least one of said dep region, dot matrix laser region, and dosing region around said dep region is formed of a transparent material as at least a portion of said housing.
10. An intelligent skin physiotherapy method based on laser lattice of electric pore-creating, characterized in that the method uses the skin physiotherapy instrument as claimed in any one of claims 2-9, comprising:
(1) selecting a mode of the needed physical therapy: the system comprises an individual dep physiotherapy mode, an individual laser dot matrix physiotherapy mode and a laser dot matrix mixed physiotherapy mode based on electroporation, wherein when the individual dep physiotherapy mode and the individual laser dot matrix physiotherapy mode are selected, the host is used for individually selecting the corresponding physiotherapy mode and using the physiotherapy probe to perform corresponding physiotherapy, the individual dep physiotherapy mode is matched with a drug delivery device to deliver drug during or after a specified first time under the action of an electric pulse with set parameters, and the individual laser dot matrix physiotherapy mode completes physiotherapy within a specified second time or controls the drug delivery device to deliver drug during or after the specified second time according to the action of the laser pulse with the set laser parameters; if the laser lattice mixed physiotherapy mode based on the electric pore forming is adopted, entering the step (2); the first and second time is 1min-1 h;
(2) firstly dep is carried out at a first time to generate LRT, then laser dot matrix is used for acting on an area acted by the dep at a second time, the skin imaging device shoots an image of the area acted by the dep, the laser dot matrix module carries out selective physiotherapy on the area acted by the dep, and then step (3) is carried out selectively according to skin conditions; the laser lattice is selected as the laser parameter which can not or can not generate a straight-through hole which is directly connected with the dermis according to the requirement;
(3) and the drug delivery device for controlling the selected parameters delivers the drug to the skin area subjected to dep and laser dot matrix physiotherapy for a third specified time to finish physiotherapy, wherein the third time is 0.1-10 min.
11. The intelligent skin treatment method according to claim 10, wherein after dep generation LRT for the first time is performed in step (2), before performing the region acting on dep for the second time using the laser lattice, further comprising step (2-1): penetrating the photosensitizer to the acting area through the administration device for the fourth time, and applying physiological saline or medical alcohol to the acting area through the administration device to clean residual photosensitizer, so that the fluorescent agent penetrating into the LRT can be captured by a fluorescence image shot by the skin imaging device, and a control signal is generated by calculating the total gray value of the collected image through division, graying and sub-image gray value, or the control signal is identified by adopting the artificial intelligence model aiming at the grayed image, therefore, the LRT falling in the sub-image area can be selectively irradiated by the pulse laser, and at least part of the pulse laser can enter the LRT.
12. The intelligent skin treatment method according to claim 11, wherein the fourth time is 3-20s and the photosensitizer is a plant pigment.
13. The intelligent skin treatment method according to claim 12, wherein the phytochrome is chlorophyll.
14. The intelligent skin treatment method according to any one of claims 10-13, wherein after the hybrid treatment mode is selected, the physiotherapy instrument is disabled from activating the drug delivery device during dep and spot laser actions.
15. A non-transitory storage medium having stored therein a computer readable program executable by the processor of any one of claims 2-9 to implement the electroporation-based laser lattice smart skin treatment method of any one of claims 10-14.
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