CN202459508U - Portable pumpless extracorporeal membrane oxygenator - Google Patents

Portable pumpless extracorporeal membrane oxygenator Download PDF

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Publication number
CN202459508U
CN202459508U CN2012200373361U CN201220037336U CN202459508U CN 202459508 U CN202459508 U CN 202459508U CN 2012200373361 U CN2012200373361 U CN 2012200373361U CN 201220037336 U CN201220037336 U CN 201220037336U CN 202459508 U CN202459508 U CN 202459508U
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CN
China
Prior art keywords
blood
hollow fiber
chamber
oxygenation chamber
inner shell
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Expired - Fee Related
Application number
CN2012200373361U
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Chinese (zh)
Inventor
周新民
周康
张致远
张智炜
刘承武
易定武
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Second Xiangya Hospital of Central South University
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Second Xiangya Hospital of Central South University
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Priority to CN2012200373361U priority Critical patent/CN202459508U/en
Application granted granted Critical
Publication of CN202459508U publication Critical patent/CN202459508U/en
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Abstract

The utility model relates to a portable pumpless extracorporeal membrane oxygenator. The portable pumpless extracorporeal membrane oxygenator comprises an oxygenation chamber which comprises an inner shell and an outer shell made of nontoxic high molecular materials. The inner and outer shells are adhered to each other in a locking manner so that a blood inlet groove communicated with a blood inlet is formed on one side of a square side surface of the oxygenation chamber and a blood outlet groove communicated with a blood outlet is formed on the other side. The inner shell is provided with a plurality of circular holes and internally provided with hollow fiber pipe membranes arranged in layers. Each layer of hollow fiber pipe membranes is formed by arranging single hollow fiber pipe in parallel. The hollow fiber pipe are separated at intervals by weaving wires. And adjacent hollow fiber pipe membranes are arranged in an interleaved mode by right-angles. Air inlet chambers are respectively arranged on two faces in the upper part of the oxygenation chamber and exhaust chambers are respectively arranged on two faces in the lower part. The air inlet chambers are separated from the exhaust chambers. Both ends of the hollow fiber pipe membranes are respectively communicated with the air inlet chamber and the exhaust chambers. The air inlet chambers are provided with air inlets connected with oxygen conduits. The exhaust chambers are provided with air outlets communicated with atmosphere.

Description

Portable pump-free type ECMO
Technical field
This utility model relates to a kind of oxygenator that external breathing is supported, particularly a kind of portable pump-free type ECMO of being used for.
Background technology
The oxygenator that is used for external breathing support commonly used at present is for there being the pump type, and it mainly is made up of oxygenator, blood pump and heat exchanger three parts.Wherein blood pump is used to provide power, blood is extracted out from human body artery/vein, via the abundant oxygenate of oxygenator; Get into heat exchanger after getting rid of carbon dioxide; To remedy the thermal losses in the extracorporeal circulation process, re-enter afterwards in the human body, reach the purpose that venous blood is changed into arterial blood.There are some defectives in it in process of clinical application:
1, as the power source blood pump of package unit; No matter be centrifugal pump or roll extrusion blood pump; In use; All can cause the mechanical damage of certain degree to blood, long-time use can cause haemolysis, platelet activation, thrombosis etc., makes product service life and safety all reduce greatly;
2, can produce big pressure in the blood pump operation process, this just requires oxygenator and heat exchanger end socket interface section firm, otherwise can cause the danger of blood plasma seepage even pipeline or device disengagement;
3, blood pump can cause bigger heat loss in operation process, and long connection pipeline can increase the weight of heat loss, thereby need add with heat exchanger to remedy the thermal losses in the operation process.But heat exchanger itself can damage the blood of flowing through in it, influences product service life, also can increase priming volume;
4, heat exchanger needs to be connected with alternating temperature case, water pump, and needs blood pump that power is provided, whole external oxygenate supportive device complex structure, complex operation, produce and use cost all higher, largely limit its clinically widely-used.
Summary of the invention
Not enough to prior art; This utility model provides a kind of portable pump-free type ECMO, and it need not blood pump power is provided, and whole device resistance is little; Only rely on the arteriovenous pressure differential to get final product the effective blood flow of assurance device; Reach oxygenated blood, get rid of the purpose of carbon dioxide, support for the respiratory failure patient provides to breathe.
ForSolve the problems of the technologies described above; The technical scheme that this utility model adopted is: a kind of portable pump-free type ECMO; Include blood mouth, blood outlet, oxygenation chamber, inlet plenum and exhaust chamber, this oxygenation chamber is that two opposite faces are foursquare square body structure, and this oxygenation chamber comprises inner shell and the shell of being processed by non-toxic high molecular material; Between the inside and outside shell with the adhesion of clamping form; Thereby a side of two square sides of oxygenation chamber form with go into that the blood mouth communicates go into the blood groove, the hemorrhage groove that opposite side formation communicates with blood outlet, this inner shell is provided with a plurality of circular holes; Inner shell inside is provided with the doughnut periosteum that multilamellar is arranged; Every layer of doughnut periosteum is arranged in parallel by single hollow fiber conduit and layer, is separated with certain interval with braided wires between each hollow fiber conduit, and adjacent two layers doughnut periosteum is arranged with the mutual interleaved mode in right angle; The two sides, top of this oxygenation chamber is respectively equipped with inlet plenum; The two sides, bottom is respectively equipped with exhaust chamber; Isolate each other between inlet plenum and the exhaust chamber; The two ends of these hollow fiber conduits communicate with inlet plenum and exhaust chamber respectively, and this inlet plenum is provided with the air inlet that connects oxygen catheter, and this exhaust chamber is provided with the gas outlet with atmosphere.
Further being improved to of such scheme, this goes into the blood mouth, blood outlet is arranged on the oxygenation chamber bottom, and the both sides, top of oxygenation chamber are provided with the air vent that communicates with inner shell inside.
Further being improved to of such scheme, the shell that is positioned at square sides are that transparent non-toxic high molecular material is processed.
Compared with prior art, the utlity model has following advantage:
1, the gas exchange membrane area in the oxygenation chamber reaches more than 1.3 ㎡; Can guarantee oxygen, carbon dioxide efficiency of transmission; Simultaneously; Take cross one another fiber pipe arrangement mode in right angle and blood mode, reduce the resistance of this utility model, guarantee that the normal patient of cardiac function can drive blood entering oxygenator through the arteriovenous pressure differential and carry out oxygenate and discharge carbon dioxide blood along Clearance Flow between pipe.
2, this utility model does not need blood pump that circulation power is provided, and the external connecting pipe road is short, and the cycling hot loss reduces greatly, thereby need not connect heat exchanger and changing device, makes that whole apparatus structure is simple, is convenient to operation.
3, this utility model does not have blood pump and changing device, and the external connecting pipe road is short again, thereby its destruction to blood constituent is less, can reduce the activation of materials such as platelet, reduces the incidence rate of complication such as haemolysis, blood coagulation, helps long-time use.In addition, the priming volume of package unit also can significantly reduce.
4, this utility model is less to the resistance of blood; Transmembrane pressure is little; Rely on human body self arteriovenous pressure differential that power is provided, thereby in running, can not produce big pressure, effectively avoid the excessive potential risk that causes oxygenation chamber blood leakage and bloody path connector to be thrown off of pressure.
5, this utility model further can with go into blood, blood outlet is arranged on the oxygenation chamber bottom; Top also can be provided with air vent; Even the doughnut tracheal rupture takes place in running like this; Cause gas to get into blood, gas also can rise to upper air vent owing to density is less, produces aeroembolism and can not get into human body with blood.
Description of drawings
Fig. 1 is this utility model internal structure sketch map.
Fig. 2 is this utility model surface structure sketch map.
Fig. 3 is the gas flow sketch map.
The specific embodiment
Below in conjunction with accompanying drawing this utility model is done further to detail:
Referring to Fig. 1-Fig. 3, this utility model includes blood mouth 1, blood outlet 2, oxygenation chamber 8, inlet plenum 5 and exhaust chamber 6.This oxygenation chamber 8 is that two opposite faces are foursquare square body structure; And this oxygenation chamber 8 comprises inner shell 11 and the shell of being processed by non-toxic high molecular material 12; Inside and outside shell 11, between 12 with the adhesion of clamping form; Thereby square sides one side of oxygenation chamber 8 form with go into that blood mouth 1 communicates go into blood groove 13, the hemorrhage groove 14 that opposite side formation communicates with blood outlet 2, this inner shell 11 is provided with a plurality of circular hole (not shown); Inner shell 11 inside are provided with the doughnut periosteum that multilamellar is arranged; Every layer of doughnut periosteum is arranged in parallel by single hollow fiber conduit 9 and layer, and 9 of each hollow fiber conduits are separated with certain interval 15 with braided wires, and adjacent two layers doughnut periosteum is arranged with the mutual interleaved mode in right angle; The two sides, top of this oxygenation chamber 8 is respectively equipped with inlet plenum 5; The two sides, bottom is respectively equipped with exhaust chamber 6; Isolate each other between inlet plenum 5 and the exhaust chamber 6; The two ends of these hollow fiber conduits 9 communicate with inlet plenum 5 and exhaust chamber 6 respectively, and this inlet plenum 5 is provided with the air inlet 3 that connects oxygen catheter, and this exhaust chamber 6 is provided with the gas outlet 4 with atmosphere.
In the present embodiment; Go into blood mouth 1, blood outlet 2 is arranged on oxygenation chamber 8 bottoms; The both sides, top of oxygenation chamber 8 are provided with the air vent 7 that communicates with inner shell 11 inside, even the doughnut tracheal rupture takes place in running like this, cause gas to get into blood; Gas also can rise to upper air vent 7 owing to density is less, produces aeroembolism and can not get into human body with blood.
In the present embodiment, the shell 10 that is positioned at this utility model square sides is made for transparent non-toxic high molecular material, can observe blood flow changes to reach whether have bubble in it.
During clinical use, patient's arterial blood gets into and goes into blood groove 13 between inner shell 11 and the shell 12 by going into blood mouth 1 through the arterypuncture conduit, gets into hollow fiber conduit 9 gap 15 outward through the circular hole on the inner shell 11; Oxygen gets into inlet plenum 5 by air inlet 3, gets in each hollow fiber conduit 9 again, guarantees that like this blood flows outside hollow fiber conduit 9, and oxygen flows in hollow fiber conduit 9, avoids blood directly to contact with oxygen.Oxygen sees through hollow fiber conduit 9 and carries out gas exchange with blood; Blood and combination with oxygen be removing carbon dioxide side by side, and the mist after the exchange gets into exhaust chamber 5, and 4 enter atmosphere through the gas outlet; Blood gets into human veins, perfect aspect outer circulation through hemorrhage groove 14, blood outlet 2.In the operation process, the gas in the oxygenation chamber 8 can be discharged by the air vent 7 on top.Thus, under the portable ECMO support of pump-free type, accomplished the effect that extracorporeal circulation partly replaces the lungs function.

Claims (3)

1. a portable pump-free type ECMO includes blood mouth, blood outlet, oxygenation chamber, inlet plenum and exhaust chamber, it is characterized in that; This oxygenation chamber is that two opposite faces are foursquare square body structure; And this oxygenation chamber comprises inner shell and the shell of being processed by non-toxic high molecular material, between the inside and outside shell with the adhesion of clamping form, thereby a side of two square sides of oxygenation chamber form with go into that the blood mouth communicates go into the blood groove; Opposite side forms the hemorrhage groove that communicates with blood outlet; This inner shell is provided with a plurality of circular holes, and inner shell inside is provided with the doughnut periosteum that multilamellar is arranged, and every layer of doughnut periosteum is arranged in parallel by single hollow fiber conduit and layer; Be separated with certain interval with braided wires between each hollow fiber conduit, and adjacent two layers doughnut periosteum is arranged with the mutual interleaved mode in right angle; The two sides, top of this oxygenation chamber is respectively equipped with inlet plenum; The two sides, bottom is respectively equipped with exhaust chamber; Isolate each other between inlet plenum and the exhaust chamber; The two ends of these hollow fiber conduits communicate with inlet plenum and exhaust chamber respectively, and this inlet plenum is provided with the air inlet that connects oxygen catheter, and this exhaust chamber is provided with the gas outlet with atmosphere.
2. portable pump-free type ECMO according to claim 1 is characterized in that this goes into the blood mouth, blood outlet is arranged on the oxygenation chamber bottom, and the both sides, top of oxygenation chamber are provided with the air vent that communicates with inner shell inside.
3. portable pump-free type ECMO according to claim 1 is characterized in that, the shell that is positioned at square sides is that transparent non-toxic high molecular material is processed.
CN2012200373361U 2012-02-07 2012-02-07 Portable pumpless extracorporeal membrane oxygenator Expired - Fee Related CN202459508U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012200373361U CN202459508U (en) 2012-02-07 2012-02-07 Portable pumpless extracorporeal membrane oxygenator

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Application Number Priority Date Filing Date Title
CN2012200373361U CN202459508U (en) 2012-02-07 2012-02-07 Portable pumpless extracorporeal membrane oxygenator

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105377404A (en) * 2013-05-17 2016-03-02 诺瓦朗公司 Oxygenator module, oxygenator and production method
CN105396187A (en) * 2015-12-29 2016-03-16 中国科学院苏州生物医学工程技术研究所 Extra corporeal membrane oxygenation device
CN107281571A (en) * 2016-04-05 2017-10-24 裴嘉阳 A kind of membrane type oxygen exchange device
CN107583120A (en) * 2017-09-20 2018-01-16 中南大学湘雅二医院 A kind of plasma exchange dialysis adsorption system
CN109224165A (en) * 2018-11-27 2019-01-18 江苏美思康医疗科技有限公司 A kind of membrane oxygenator of the integrated centrifugal pump with alternating temperature
US10610629B2 (en) 2015-05-07 2020-04-07 Novalung Gmbh Device with inlet portion for treating a biological liquid
CN111744065A (en) * 2020-06-29 2020-10-09 东莞科威医疗器械有限公司 Oxycoated silk membrane, oxygenating part and oxygenator for ECMO
CN111992053A (en) * 2020-08-17 2020-11-27 杭州科百特科技有限公司 Gas exchange membrane, preparation method thereof and gas exchange assembly
US11541157B2 (en) 2019-06-18 2023-01-03 Michigan Critical Care Consultants, Inc. Membrane oxygenator with gas exchange fiber lumen access based on fiber effective length
CN116271306A (en) * 2023-05-24 2023-06-23 北京清瀚医疗科技有限公司 Polygonal artificial membrane lung for in-vitro carbon dioxide removal and preparation method thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105377404A (en) * 2013-05-17 2016-03-02 诺瓦朗公司 Oxygenator module, oxygenator and production method
US10286137B2 (en) 2013-05-17 2019-05-14 Novalung Gmbh Oxygenator module, oxygenator and production method
US10610629B2 (en) 2015-05-07 2020-04-07 Novalung Gmbh Device with inlet portion for treating a biological liquid
CN105396187A (en) * 2015-12-29 2016-03-16 中国科学院苏州生物医学工程技术研究所 Extra corporeal membrane oxygenation device
CN107281571A (en) * 2016-04-05 2017-10-24 裴嘉阳 A kind of membrane type oxygen exchange device
CN107583120A (en) * 2017-09-20 2018-01-16 中南大学湘雅二医院 A kind of plasma exchange dialysis adsorption system
CN109224165A (en) * 2018-11-27 2019-01-18 江苏美思康医疗科技有限公司 A kind of membrane oxygenator of the integrated centrifugal pump with alternating temperature
US11541157B2 (en) 2019-06-18 2023-01-03 Michigan Critical Care Consultants, Inc. Membrane oxygenator with gas exchange fiber lumen access based on fiber effective length
CN111744065A (en) * 2020-06-29 2020-10-09 东莞科威医疗器械有限公司 Oxycoated silk membrane, oxygenating part and oxygenator for ECMO
CN111992053A (en) * 2020-08-17 2020-11-27 杭州科百特科技有限公司 Gas exchange membrane, preparation method thereof and gas exchange assembly
CN116271306A (en) * 2023-05-24 2023-06-23 北京清瀚医疗科技有限公司 Polygonal artificial membrane lung for in-vitro carbon dioxide removal and preparation method thereof
CN116271306B (en) * 2023-05-24 2024-03-12 北京清瀚医疗科技有限公司 Polygonal artificial membrane lung for in-vitro carbon dioxide removal and preparation method thereof

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20121003

Termination date: 20190207

CF01 Termination of patent right due to non-payment of annual fee